David Sinclair, A.O., Ph.D.
David A. Sinclair, A.O., Ph.D. is a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is best known for his work on understanding why we age and how to slow its effects. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995. He worked as a postdoctoral researcher at M.I.T. with Dr. Leonard Guarente where he co discovered a cause of aging for yeast as well as the role of Sir2 in epigenetic changes driven by genome instability. More information →
Bruce A. Yankner, M.D., Ph.D.
Bruce A. Yankner, M.D., Ph.D. is Professor of Genetics and Neurology at Harvard Medical School, Director of the Harvard Neurodegeneration Training Program, and Co-Director of the Paul F. Glenn Center for Biology of Aging Research. Dr. Yankner graduated from Princeton University, received his M.D. and Ph.D. from Stanford University, and did a residency at Massachusetts General Hospital. His work has contributed to understanding pathogenic mechanisms in Alzheimer’s disease, Down’s syndrome and Parkinson’s disease, beginning with the initial observation that amyloid beta protein is a toxic molecule, and later with investigations into the roles of presenilin proteins, notch and wnt in neuronal signaling and pathology. More information →
Marcia Haigis, Ph.D.
Marcia C. Haigis, Ph.D. is an Associate Professor in the Department of Cell Biology at Harvard Medical School and a member of the Paul F. Glenn Center for Biology of Aging Research. Dr. Haigis received her Ph.D. in Biochemistry from the University of Wisconsin in 2002 studying protein chemistry. She performed postdoctoral research at MIT in 2006 where she made fundamental discoveries connecting sirtuin function to mitochondrial metabolism. Dr. Haigis joined the Harvard faculty as an Assistant Professor in 2006. More information →
Amy J. Wagers, Ph.D.
Amy Wagers is the Forst Family Professor of Stem Cell and Regenerative Biology at Harvard University, Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center, an HHMI Early Career Scientist, and a member of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School. Dr. Wagers received her Ph.D. in Immunology and Microbial Pathogenesis from Northwestern University, and completed postdoctoral training in stem cell biology at Stanford University. More information →