HMS Virology

Publications

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2019


Barnett KC, Coronas-Serna JM, Zhou W, Ernandes MJ, Cao A, Kranzusch PJ, Kagan JC. Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Cell. 2019 Mar 7;176(6):1432-1446.e11. doi: 10.1016/j.cell.2019.01.049. Epub 2019 Feb 28. PMID: 30827685  read article


Park DE, Cheng J, Berrios C, Montero J, Cortés-Cros M, Ferretti S, Arora R, Tillgren ML, Gokhale PC, DeCaprio JA. Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1027-1032. doi: 10.1073/pnas.1818798116. Epub 2018 Dec 31. PMID: 30598450 PMCID: PMC6338866 [Available on 2019-07-15] read article


Fischinger S, Boudreau CM, Butler AL, Streeck H, Alter G. Sex differences in vaccine-induced humoral immunity. Semin Immunopathol. 2019 Mar;41(2):239-249. doi: 10.1007/s00281-018-0726-5. Epub 2018 Dec 13. PMID: 30547182 PMCID: PMC6373179 read article


Boudreau CM, Alter G. Extra-Neutralizing FcR-Mediated Antibody Functions for a Universal Influenza Vaccine. 18 March 2019 | https://doi.org/10.3389/fimmu.2019.00440


Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, Shields JL, Lavine CL, Ghantous F, Rist M, Bayne MG, Neubauer GH, McMahan K, Peng H, Chéneau C, Jones JJ, Zeng J, Ochsenbauer C, Nkolola JP, Stephenson KE, Chen B, Gnanakaran S, Bonsignori M, Williams LD, Haynes BF, Doria-Rose N, Mascola JR, Montefiori DC, Barouch DH, Korber B. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host Microbe. 2019 Jan 9;25(1):59-72.e8. doi: 10.1016/j.chom.2018.12.001. PMID: 30629920 PMCID: PMC6331341 read article


Juillard F, De León Vázquez E, Tan M, Li S, Kaye KM. Kaposi's Sarcoma-Associated Herpesvirus LANA-Adjacent Regions with Distinct Functions in Episome Segregation or Maintenance. J Virol. 2019 Mar 5;93(6). pii: e02158-18. doi: 10.1128/JVI.02158-18. Print 2019 Mar 15. PMID: 30626680 PMCID: PMC6401465 [Available on 2019-09-05] read article


Eaglesham JB, Pan Y, Kupper TS, Kranzusch PJ. Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling. Nature. 2019 Feb;566(7743):259-263. doi: 10.1038/s41586-019-0928-6. Epub 2019 Feb 6. PMID: 30728498 read article


Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ. Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature. 2019 Mar;567(7747):194-199. doi: 10.1038/s41586-019-0953-5. Epub 2019 Feb 20. PMID: 30787435 read article


Barnett KC, Coronas-Serna JM, Zhou W, Ernandes MJ, Cao A, Kranzusch PJ, Kagan JC.Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Cell. 2019 Mar 7;176(6):1432-1446.e11. doi: 10.1016/j.cell.2019.01.049. Epub 2019 Feb 28. PMID: 30827685 read article


Piantadosi A, Freije CA, Gosmann C, Ye S, Park D, Schaffner SF, Tully DC, Allen TM, Dong KL Sabeti PC, Kwon DS. Metagenomic Sequencing of HIV-1 in the Blood and Female Genital Tract Reveals Little Quasispecies Diversity during Acute Infection. J Virol. 2019 Jan 4;93(2). pii: e00804-18. doi: 10.1128/JVI.00804-18. Print 2019 Jan 15. PMID: 30381486 PMCID: PMC6321908 read article


Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Nikić-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB 3rd, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W. Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. Nature. 2019 Apr;568(7752):415-419. doi: 10.1038/s41586-019-1101-y. Epub 2019 Apr 10. PMID: 30971821 read article


Gardner MR, Fetzer I, Kattenhorn LM, Davis-Gardner ME, Zhou AS, Alfant B, Weber JA, Kondur HR, Martinez-Navio JM, Fuchs SP, Desrosiers RC, Gao G, Lifson JD, Farzan M. Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies. Mol Ther. 2019 Mar 6;27(3):650-660. doi: 10.1016/j.ymthe.2019.01.004. Epub 2019 Jan 12. PMID: 30704961 PMCID: PMC6403482 [Available on 2020-03-06] read article


Fetzer I, Davis-Gardner ME, Gardner MR, Alfant B, Weber JA, Prasad NR, Zhou AS, Farzan M. A Coreceptor-Mimetic Peptide Enhances the Potency of V3-Glycan Antibodies. J Virol. 2019 Feb 19;93(5). pii: e01653-18. doi: 10.1128/JVI.01653-18. Print 2019 Mar 1. PMID: 30541842 PMCID: PMC6384058 [Available on 2019-08-19] read article


Carey CM, Govande AA, Cooper JM, Hartley MK, Kranzusch PJ, Elde NC. Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates. Cell Host Microbe. 2019 Feb 13;25(2):336-343.e4. doi: 10.1016/j.chom.2019.01.001. Epub 2019 Jan 31. PMID: 30713099 read article


Lim MY, Paulo JA, Gygi SP. Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model. read article


Metsky HC, Siddle KJ, Gladden-Young A, Qu J, Yang DK, Brehio P, Goldfarb A, Piantadosi A, Wohl S, Carter A, Lin AE, Barnes KG, Tully DC, Corleis B, Hennigan S, Barbosa-Lima G, Vieira YR, Paul LM, Tan AL, Garcia KF, Parham LA, Odia I, Eromon P, Folarin OA, Goba A; Viral Hemorrhagic Fever Consortium, Simon-Lorière E, Hensley L, Balmaseda A, Harris E, Kwon DS,, Allen TM, Runstadler JA, Smole S, Bozza FA, Souza TML, Isern S, Michael SF, Lorenzana I, Gehrke L, Bosch I, Ebel G, Grant DS, Happi CT, Park DJ, Gnirke A, Sabeti PC, Matranga CB. Capturing sequence diversity in metagenomes with comprehensive and scalable probe design. Nat Biotechnol. 2019 Feb;37(2):160-168. doi: 10.1038/s41587-018-0006-x. Epub 2019 Feb 4. PMID: 30718881 read article


Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ. Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature. 2019 Mar;567(7747):194-199. doi: 10.1038/s41586-019-0953-5. Epub 2019 Feb 20. PMID: 30787435 read article


Vong M, Manny AR, Smith KL, Gao W, Nibert ML. Beta vulgaris mitovirus 1 in diverse cultivars of beet and chard. Virus Res. 2019 Mar 8;265:80-87. doi: 10.1016/j.virusres.2019.02.008. [Epub ahead of print] PMID: 30853586  read article


Pan D, Li G, Morris-Love J, Qi S, Feng L, Mertens ME, Jurak I, Knipe DM, Coen DM. Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs. MBio. 2019 Feb 12;10(1). pii: e02856-18. doi: 10.1128/mBio.02856-18. PMID: 30755517 PMCID: PMC6372804 read article


Orzalli MH. Human Skin Explants Recapitulate Key Features of HSV-1 Infections. J Invest Dermatol. 2019 Mar;139(3):519-521. doi: 10.1016/j.jid.2018.09.015. PMID: 30797319 read article


de Oliveira Mann CC, Orzalli MH, King DS, Kagan JC, Lee ASY, Kranzusch PJ. Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation. Cell Rep. 2019 Apr 23;27(4):1165-1175.e5. doi: 10.1016/j.celrep.2019.03.098. PMID: 31018131 read article


Pyle JD, Whelan SPJ. RNA ligands activate the Machupo virus polymerase and guide promoter usage. Submitted to the National Academy of Sciences of the USA.


Schade AE, Oser MG, Nicholson HE, DeCaprio JA. Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB. Oncogene. 2019 Mar 4. doi: 10.1038/s41388-019-0767-9. [Epub ahead of print] PMID: 30833638 read article


Watanabe A, McCarthy KR, Kuraoka M, Schmidt AG, Adachi Y, Onodera T, Tonouchi K, Caradonna TM, Bajic G, Song S, McGee CE, Sempowski GD, Feng F, Urick P, Kepler TB, Takahashi Y, Harrison SC, Kelsoe G. Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 2019 May 16;177(5):1124-1135.e16. doi: 10.1016/j.cell.2019.03.048. PMID: 31100267 read article


Bajic G, van der Poel CE, Kuraoka M, Schmidt AG, Carroll MC, Kelsoe G, Harrison SC. Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. Sci Rep. 2019 Mar 5;9(1):3492. doi: 10.1038/s41598-019-40175-8. PMID: 30837606 PMCID: PMC6401307 read article


Schmidt AG, Lee K, Yang PL, Harrison SC. Correction: Small-molecule inhibitors of dengue-virus entry. PLoS Pathog. 2019 Jan 31;15(1):e1007553. doi: 10.1371/journal.ppat.1007553. eCollection 2019 Jan. PMID: 30703168 PMCID: PMC6355023 read article


Watanabe A, Su KY, Kuraoka M, Yang G, Reynolds AE, Schmidt AG, Harrison SC, Haynes BF, St Clair EW, Kelsoe G. Self-tolerance curtails the B cell repertoire to microbial epitopes. JCI Insight. 2019 May 16;4(10). pii: 122551. doi: 10.1172/jci.insight.122551. eCollection 2019 May 16. PMID: 31092727 read article


Usmani SM, Murooka TT, Deruaz M, Koh WH, Sharaf RR, Di Pilato M, Power KA, Lopez P, Hnatiuk R, Vrbanac VD, Tager AM, Allen TM, Luster AD, Mempel TR. HIV-1 Balances the Fitness Costs and Benefits of Disrupting the Host Cell Actin Cytoskeleton Early after Mucosal Transmission. Cell Host Microbe. 2019 Jan 9;25(1):73-86.e5. doi: 10.1016/j.chom.2018.12.008. PMID: 30629922 read article


Einkauf KB, Lee GQ, Gao C, Sharaf R, Sun X, Hua S, Chen SM, Jiang C, Lian X, Chowdhury FZ, Rosenberg ES, Chun TW, Li JZ, Yu XG, Lichterfeld M. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest. 2019 Mar 1;129(3):988-998. doi: 10.1172/JCI124291. Epub 2019 Jan 28. PMID: 30688658 PMCID: PMC6391088 [Available on 2019-06-01] read article


Jiang C, Trudeau SJ, Cheong TC, Guo R, Teng M, Wang LW, Wang Z, Pighi C, Gautier-Courteille C, Ma Y, Jiang S, Wang C, Zhao B, Paillard L, Doench JG, Chiarle R, Gewurz BE. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation.Cell Rep. 2019 Jul 30;28(5):1307-1322.e8. doi: 10.1016/j.celrep.2019.06.079. PMID: 31365872  read article


Wang LW, Shen H, Nobre L, Ersing I, Paulo JA, Trudeau S, Wang Z, Smith NA, Ma Y, Reinstadler B, Nomburg J, Sommermann T, Cahir-McFarland E, Gygi SP, Mootha VK, Weekes MP, Gewurz BE. Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation. Cell Metab. 2019 Jun 27. pii: S1550-4131(19)30306-7. doi: 10.1016/j.cmet.2019.06.003. [Epub ahead of print] PMID:31257153  read article


Wang LW, Wang Z, Ersing I, Nobre L, Guo R, Jiang S, Trudeau S, Zhao B, Weekes MP, Gewurz BE. Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival. PLoS Pathog. 2019 Sep 13;15(9):e1008030. PMID: 31518366

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2018


Bentley P, Tan MJA, McBride AA, White EA, Howley PM. The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA. J Virol. 2018 Jul 17;92(15). pii: e00356-18. doi: 10.1128/JVI.00356-18. Print 2018 Aug 1. PMID: 29848583 PMCID: PMC6052296 read article


Abbink P, Kirilova M, Boyd M, Mercado N, Li Z, Nityanandam R, Nanayakkara O, Peterson R, Larocca RA, Aid M, Tartaglia L, Mutetwa T, Blass E, Jetton D, Maxfield LF, Borducchi EN, Badamchi-Zadeh A, Handley S, Zhao G, Virgin HW, Havenga MJ, Barouch DH. Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors. J Virol. 2018 Feb 26;92(6). pii: e01924-17. doi: 10.1128/JVI.01924-17. Print 2018 Mar 15. PMID: 29298888 PMCID: PMC5827402 read article


Blass E, Aid M, Martinot AJ, Larocca RA, Kang ZH, Badamchi-Zadeh A, Penaloza-MacMaster P, Reeves RK, Barouch DH. Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018 May 14;92(11). pii: e02103-17. doi: 10.1128/JVI.02103-17. Print 2018 Jun 1. PMID: 29514912 PMCID: PMC5952142 read article


Badamchi-Zadeh A, Moynihan KD, Larocca RA, Aid M, Provine NM, Iampietro MJ, Kinnear E, Penaloza-MacMaster P, Abbink P, Blass E, Tregoning JS, Irvine DJ, Barouch DH. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. J Immunol. 2018 Nov 1;201(9):2744-2752. doi: 10.4049/jimmunol.1800885. Epub 2018 Sep 24. PMID: 30249811 PMCID: PMC6196294  read article


Modjarrad K, Lin L, George SL, Stephenson KE, Eckels KH, De La Barrera RA, Jarman RG, Sondergaard E, Tennant J, Ansel JL, Mills K, Koren M, Robb ML, Barrett J, Thompson J, Kosel AE, Dawson P, Hale A, Tan CS, Walsh SR, Meyer KE, Brien J, Crowell TA, Blazevic A, Mosby K, Larocca RA, Abbink P, Boyd M, Bricault CA, Seaman MS, Basil A, Walsh M, Tonwe V, Hoft DF, Thomas SJ, Barouch DH, Michael NL. Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials. Lancet. 2018 Feb 10;391(10120):563-571. doi: 10.1016/S0140-6736(17)33106-9. Epub 2017 Dec 5. PMID: 29217375 PMCID: PMC5884730 read article


Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH. Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors. J Virol. 2018 May 14;92(11). pii: e00159-18. doi: 10.1128/JVI.00159-18. Print 2018 Jun 1. PMID: 29563285 PMCID: PMC5952169 read article


Badamchi-Zadeh A, Tartaglia LJ, Abbink P, Bricault CA, Liu PT, Boyd M, Kirilova M, Mercado NB, Nanayakkara OS, Vrbanac VD, Tager AM, Larocca RA, Seaman MS, Barouch DH. Therapeutic Efficacy of Vectored PGT121 Gene Delivery in HIV-1-Infected Humanized Mice. J Virol. 2018 Mar 14;92(7). pii: e01925-17. doi: 10.1128/JVI.01925-17. Print 2018 Apr 1. PMID: 29321310 PMCID: PMC5972893 read article


Bricault CA, Kovacs JM, Badamchi-Zadeh A, McKee K, Shields JL, Gunn BM, Neubauer GH, Ghantous F, Jennings J, Gillis L, Perry J, Nkolola JP, Alter G, Chen B, Stephenson KE, Doria-Rose N, Mascola JR, Seaman MS, Barouch DH. Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs. J Virol. 2018 Jun 13;92(13). pii: e00369-18. doi: 10.1128/JVI.00369-18. Print 2018 Jul 1. PMID: 29643249 PMCID: PMC6002713 read article


Kang ZH, Bricault CA, Borducchi EN, Stephenson KE, Seaman MS, Pau M, Schuitemaker H, van Manen D, Wegmann F, Barouch DH. Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys. J Virol. 2018 Jul 17;92(15). pii: e00537-18. doi: 10.1128/JVI.00537-18. Print 2018 Aug 1. PMID: 29793950 PMCID: PMC6052297 read article


Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, LaBranche CC, van Gils MJ, Bricault CA, Barouch DH, Crotty S, Silvestri G, Kasturi S, Pulendran B, Wilson IA, Montefiori DC, Sanders RW, Ward AB, Moore JP. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. PLoS Pathog. 2018 Feb 23;14(2):e1006913. doi: 10.1371/journal.ppat.1006913. eCollection 2018 Feb. PMID: 29474444 PMCID: PMC5841823 read article


Cabral JM, Oh HS, Knipe DM. ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress. Elife. 2018 Nov 22;7. pii: e40228. doi: 10.7554/eLife.40228. PMID: 30465651 PMCID: PMC6307862 read article


Chiang JJ, Sparrer KMJ, van Gent M, Lässig C, Huang T, Osterrieder N, Hopfner KP, Gack MU. Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity. Nat Immunol. 2018 Jan;19(1):53-62. doi: 10.1038/s41590-017-0005-y. Epub 2017 Nov 27. PMID: 29180807 PMCID: PMC5815369  read article


Sanchez JG, Sparrer KMJ, Chiang C, Reis RA, Chiang JJ, Zurenski MA, Wan Y, Gack MU, Pornillos O. TRIM25 Binds RNA to Modulate Cellular Anti-viral Defense. J Mol Biol. 2018 Dec 7;430(24):5280-5293. doi: 10.1016/j.jmb.2018.10.003. Epub 2018 Oct 17. PMID: 30342007 PMCID: PMC6289755 [Available on 2019-12-07] read article


D'Cruz AA, Kershaw NJ, Hayman TJ, Linossi EM, Chiang JJ, Wang MK, Dagley LF, Kolesnik TB, Zhang JG, Masters SL, Griffin MDW, Gack MU, Murphy JM, Nicola NA, Babon JJ, Nicholson SE. Identification of a second binding site on the TRIM25 B30.2 domain. Biochem J. 2018 Jan 23;475(2):429-440. doi: 10.1042/BCJ20170427. PMID: 29259080 PMCID: PMC6200327 read article


de Wispelaere M, Lian W, Potisopon S, Li PC, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, Yang P. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chem Biol. 2018 Aug 16;25(8):1006-1016.e8. doi: 10.1016/j.chembiol.2018.05.011. Epub 2018 Jun 21. PMID: 29937406 PMCID: PMC6097893 [Available on 2019-08-16] read article


Chen W, Dev J, Mezhyrova J, Pan L, Piai A, Chou JJ. The Unusual Transmembrane Partition of the Hexameric Channel of the Hepatitis C Virus. Structure. 2018 Apr 3;26(4):627-634.e4. doi: 10.1016/j.str.2018.02.011. Epub 2018 Mar 15. PMID: 29551287 PMCID: PMC5884736 read article


Dudek AM, Pillay S, Puschnik AS, Nagamine CM, Cheng F, Qiu J, Carette JE, Vandenberghe LH. An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor. J Virol. 2018 Mar 14;92(7). pii: e02213-17. doi: 10.1128/JVI.02213-17. Print 2018 Apr 1. PMID: 29343568 PMCID: PMC5972900 read article


Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A, Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I, Gehrke L, Zhang F, Sabeti PC. Field-deployable viral diagnostics using CRISPR-Cas13. Science. 2018 Apr 27;360(6387):444-448. doi: 10.1126/science.aas8836. PMID: 29700266 PMCID: PMC6197056  read article


Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC. STING-dependent translation inhibition restricts RNA virus replication. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2058-E2067. doi: 10.1073/pnas.1716937115. Epub 2018 Feb 12. PMID: 29440426 PMCID: PMC5834695 read article


Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A, Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I, Gehrke L, Zhang F, Sabeti PC. Field-deployable viral diagnostics using CRISPR-Cas13. Science. 2018 Apr 27;360(6387):444-448. doi: 10.1126/science.aas8836. PMID: 29700266 PMCID: PMC6197056 read article


Siddle KJ, Eromon P, Barnes KG, Mehta S, Oguzie JU, Odia I, Schaffner SF, Winnicki SM, Shah RR, Qu J, Wohl S, Brehio P, Iruolagbe C, Aiyepada J, Uyigue E, Akhilomen P, Okonofua G, Ye S, Kayode T, Ajogbasile F, Uwanibe J, Gaye A, Momoh M, Chak B, Kotliar D, Carter A, Gladden-Young A, Freije CA, Omoregie O, Osiemi B, Muoebonam EB, Airende M, Enigbe R, Ebo B, Nosamiefan I, Oluniyi P, Nekoui M, Ogbaini-Emovon E, Garry RF, Andersen KG, Park DJ, Yozwiak NL, Akpede G, Ihekweazu C, Tomori O, Okogbenin S, Folarin OA, Okokhere PO, MacInnis BL, Sabeti PC, Happi CT. Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018. N Engl J Med. 2018 Nov 1;379(18):1745-1753. doi: 10.1056/NEJMoa1804498. Epub 2018 Oct 17. PMID: 30332564 PMCID: PMC6181183 read article


Frost TC, Gewurz BE. Epigenetic crossroads of the Epstein-Barr virus B-cell relationship. Curr Opin Virol. 2018 Oct;32:15-23. doi: 10.1016/j.coviro.2018.08.012. Epub 2018 Sep 15. PMID: 30227386 PMCID: PMC6263794 [Available on 2019-10-01] read article


Peters C, Paget M, Tshilenge KT, Saha D, Antoszczyk S, Baars A, Frost T, Martuza RL, Wakimoto H, Rabkin SD. Restriction of Replication of Oncolytic Herpes Simplex Virus with a Deletion of γ34.5 in Glioblastoma Stem-Like Cells. J Virol. 2018 Jul 17;92(15). pii: e00246-18. doi: 10.1128/JVI.00246-18. Print 2018 Aug 1. PMID: 29793956 PMCID: PMC6052301 read article


Yang E, Gardner MR, Zhou AS, Farzan M, Arvin AM, Oliver SL. HIV-1 inhibitory properties of eCD4-Igmim2 determined using an Env-mediated membrane fusion assay. PLoS One. 2018 Oct 25;13(10):e0206365. doi: 10.1371/journal.pone.0206365. eCollection 2018. PMID: 30359435 PMCID: PMC6201953 read article


Otsuka Y, Schmitt K, Quinlan BD, Gardner MR, Alfant B, Reich A, Farzan M, Choe H. Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies. PLoS Pathog. 2018 Aug 20;14(8):e1007238. doi: 10.1371/journal.ppat.1007238. eCollection 2018 Aug. PMID: 30125330 PMCID: PMC6117093 read article


Mou H, Zhong G, Gardner MR, Wang H, Wang YW, Cheng D, Farzan M. Conditional Regulation of Gene Expression by Ligand-Induced Occlusion of a MicroRNA Target Sequence. Mol Ther. 2018 May 2;26(5):1277-1286. doi: 10.1016/j.ymthe.2018.02.021. Epub 2018 Feb 27. PMID: 29567311 PMCID: PMC5993935 read article


Fetzer I, Gardner MR, Davis-Gardner ME, Prasad NR, Alfant B, Weber JA, Farzan M. eCD4-Ig Variants That More Potently Neutralize HIV-1.J Virol. 2018 May 29;92(12). pii: e02011-17. doi: 10.1128/JVI.02011-17. Print 2018 Jun 15. PMID: 29593050 PMCID: PMC5974481 read article


Gebre M, Nomburg JL, Gewurz BE. CRISPR-Cas9 Genetic Analysis of Virus-Host Interactions. Viruses. 2018 Jan 30;10(2). pii: E55. doi: 10.3390/v10020055. PMID: 29385696 PMCID: PMC5850362 read article


Anahtar, MN, Gootenberg, DB, Mitchell, CM, Kwon, DS. Cervicovaginal Microbiota and Reproductive Health: The Virtue of Simplicity. Cell Host Microbe. 2018 Feb 14;23(2):159-168. doi: 10.1016/j.chom.2018.01.013. PMID: 29447695 read article


Ita S, Hill AK, Lam EC, Dufort FJ, Yang X, Newman R, Leviyang S, Fofana IB, Johnson WE. High-Resolution Sequencing of Viral Populations during Early Simian Immunodeficiency Virus Infection Reveals Evolutionary Strategies for Rapid Escape from Emerging Env-Specific Antibody Responses. J Virol. 2018 Mar 14;92(7). pii: e01574-17. doi: 10.1128/JVI.01574-17. Print 2018 Apr 1. PMID: 29343575 PMCID: PMC5972902  read article


Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH. Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors. J Virol. 2018 May 14;92(11). pii: e00159-18. doi: 10.1128/JVI.00159-18. Print 2018 Jun 1. PMID: 29563285 PMCID: PMC5952169 read article


Badamchi-Zadeh A, Moynihan KD, Larocca RA, Aid M, Provine NM, Iampietro MJ, Kinnear E, Penaloza-MacMaster P, Abbink P, Blass E, Tregoning JS, Irvine DJ, Barouch DH. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. J Immunol. 2018 Nov 1;201(9):2744-2752. doi: 10.4049/jimmunol.1800885. Epub 2018 Sep 24. PMID: 30249811 PMCID: PMC6196294  read article


Ita S, Hill AK, Lam EC, Dufort FJ, Yang X, Newman R, Leviyang S, Fofana IB, Johnson WE. High-Resolution Sequencing of Viral Populations during Early Simian Immunodeficiency Virus Infection Reveals Evolutionary Strategies for Rapid Escape from Emerging Env-Specific Antibody Responses. J Virol. 2018 Mar 14;92(7). pii: e01574-17. doi: 10.1128/JVI.01574-17. Print 2018 Apr 1. PMID: 29343575 PMCID: PMC5972902 read article


Welles HC, Jennewein MF, Mason RD, Narpala S, Wang L, Cheng C, Zhang Y, Todd JP, Lifson JD, Balazs AB, Alter G, McDermott AB, Mascola JR, Roederer M. Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge. PLoS Pathog. 2018 Dec 5;14(12):e1007395. doi: 10.1371/journal.ppat.1007395. eCollection 2018 Dec. PMID: 30517201 PMCID: PMC6296672 read article


Jennewein MF, Butler AL, Alter G. Neonate-omics: Charting the Unknown Immune Response in Early Life. Cell. 2018 Aug 23;174(5):1051-1053. doi: 10.1016/j.cell.2018.08.001. PMID: 30142343 read article


Jennewein MF, Goldfarb I, Dolatshahi S, Cosgrove C, Noelette FJ, et al. Fc glycan-mediated regulation of placental antibody transfer. Cell Press 2018.


Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH. Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors. J Virol. 2018 May 14;92(11). pii: e00159-18. doi: 10.1128/JVI.00159-18. Print 2018 Jun 1. PMID: 29563285 PMCID: PMC5952169 read article


Kang ZH, Bricault CA, Borducchi EN, Stephenson KE, Seaman MS, Pau M, Schuitemaker H, van Manen D, Wegmann F, Barouch DH. Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys. J Virol. 2018 Jul 17;92(15). pii: e00537-18. doi: 10.1128/JVI.00537-18. Print 2018 Aug 1. PMID: 29793950 PMCID: PMC6052297 read article


Blass E, Aid M, Martinot AJ, Larocca RA, Kang ZH, Badamchi-Zadeh A, Penaloza-MacMaster P, Reeves RK, Barouch DH. Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection. J Virol. 2018 May 14;92(11). pii: e02103-17. doi: 10.1128/JVI.02103-17. Print 2018 Jun 1. PMID: 29514912 PMCID: PMC5952142 read article


Lawler JL, Mukherjee P, Coen DM. Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3'-to-5' Direction and Is Dependent on the 3'-to-5' Exonuclease Active Site. J Virol. 2018 Feb 12;92(5). pii: e01813-17. doi: 10.1128/JVI.01813-17. Print 2018 Mar 1. PMID: 29237844 PMCID: PMC5809741 read article


Lawler JL, Coen DM. HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression. J Gen Virol. 2018 Oct;99(10):1432-1437. doi: 10.1099/jgv.0.001138. Epub 2018 Sep 3. PMID: 30176164 read article


Lee JS, Raja P, Pan D, Pesola JM, Coen DM, Knipe DM. CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection. MBio. 2018 Feb 6;9(1). pii: e02372-17. doi: 10.1128/mBio.02372-17. PMID: 29437926 PMCID: PMC5801469 read article


Boisen ML, Hartnett JN, Shaffer JG, Goba A, Momoh M, Sandi JD, Fullah M, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Koval AP, Cross RW, Barnes KG, Lachenauer AE, Lin AE, Nekoui M, Kotliar D, Winnicki SM, Siddle KJ, Gbakie M, Fonnie M, Koroma VJ, Kanneh L, Kulakosky PC, Hastie KM, Wilson RB, Andersen KG, Folarin OO, Happi CT, Sabeti PC, Geisbert TW, Saphire EO, Khan SH, Grant DS, Schieffelin JS, Branco LM, Garry RF. Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever. Sci Rep. 2018 Apr 12;8(1):5939. doi: 10.1038/s41598-018-24246-w. PMID: 29651117 PMCID: PMC5897328 read article


Whitney JB, Lim SY, Osuna CE, Kublin JL, Chen E, Yoon G, Liu PT, Abbink P, Borducci EN, Hill A, Lewis MG, Geleziunas R, Robb ML, Michael NL, Barouch DH. Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy. Nat Commun. 2018 Dec 21;9(1):5429. doi: 10.1038/s41467-018-07881-9. PMID: 30575753 PMCID: PMC6303321 read article


Badamchi-Zadeh A, Tartaglia LJ, Abbink P, Bricault CA, Liu PT, Boyd M, Kirilova M, Mercado NB, Nanayakkara OS, Vrbanac VD, Tager AM, Larocca RA, Seaman MS, Barouch DH. Therapeutic Efficacy of Vectored PGT121 Gene Delivery in HIV-1-Infected Humanized Mice. J Virol. 2018 Mar 14;92(7). pii: e01925-17. doi: 10.1128/JVI.01925-17. Print 2018 Apr 1. PMID: 29321310 PMCID: PMC5972893 read article


Boesch AW, Kappel JH, Mahan AE, Chu TH, Crowley AR, Osei-Owusu NY, Alter G, Ackerman ME. Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands. Biotechnol Bioeng. 2018 May;115(5):1265-1278. doi: 10.1002/bit.26545. Epub 2018 Feb 1. PMID: 29315477 PMCID: PMC5906797 read article


Alter G, Dowell KG, Brown EP, Suscovich TJ, Mikhailova A, Mahan AE, Walker BD, Nimmerjahn F, Bailey-Kellogg C, Ackerman ME. High-resolution definition of humoral immune response correlates of effective immunity against HIV. Mol Syst Biol. 2018 Mar 26;14(3):e7881. doi: 10.15252/msb.20177881. PMID: 29581149 PMCID: PMC5868198 read article


Nibert ML, Manny AR, Debat HJ, Firth AE, Bertini L, Caruso C. A barnavirus sequence mined from a transcriptome of the Antarctic pearlwort Colobanthus quitensis. Arch Virol. 2018 Jul;163(7):1921-1926. doi: 10.1007/s00705-018-3794-x. Epub 2018 Mar 7. PMID: 29516246 PMCID: PMC5999160 read article


Meyers JM, Grace M, Uberoi A, Lambert PF, Munger K. Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses. Front Microbiol. 2018 Mar 8;9:389. doi: 10.3389/fmicb.2018.00389. eCollection 2018. PMID: 29568286 PMCID: PMC5852067 read article


Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC. STING-dependent translation inhibition restricts RNA virus replication. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2058-E2067. doi: 10.1073/pnas.1716937115. Epub 2018 Feb 12. PMID: 29440426 PMCID: PMC5834695 read article


Gebre M, Nomburg JL, Gewurz BE. CRISPR-Cas9 Genetic Analysis of Virus-Host Interactions. Viruses. 2018 Jan 30;10(2). pii: E55. doi: 10.3390/v10020055. PMID: 29385696 PMCID: PMC5850362 read article


Merkl PE, Orzalli MH, Knipe DM. Mechanisms of Host IFI16, PML, and Daxx Protein Restriction of Herpes Simplex Virus 1 Replication. J Virol. 2018 Apr 27;92(10). pii: e00057-18. doi: 10.1128/JVI.00057-18. Print 2018 May 15. PMID: 29491153 PMCID: PMC5923075 read article


Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC. An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Mol Cell. 2018 Sep 6;71(5):825-840.e6. doi: 10.1016/j.molcel.2018.07.009. Epub 2018 Aug 9. PMID: 30100266 PMCID: PMC6411291 [Available on 2019-09-06] read article


Peters C, Paget M, Tshilenge KT, Saha D, Antoszczyk S, Baars A, Frost T, Martuza RL, Wakimoto H, Rabkin SD. Restriction of γ34.5-deleted oncolytic herpes simplex virus replication in glioblastoma stem-like cells. J Virol. 2018 May 23. pii: JVI.00246-18. doi: 10.1128/JVI.00246-18 PMID: 29793956 PMCID: PMC6052301
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Saha D, Wakimoto H, Peters CW, Antoszczyk SJ, Rabkin SD, Martuza RL. Combinatorial Effects of VEGFR Kinase Inhibitor Axitinib and Oncolytic Virotherapy in Mouse and Human Glioblastoma Stem-Like Cell Models. Clin Cancer Res. 2018 Jul 15;24(14):3409-3422. doi: 10.1158/1078-0432.CCR-17-1717. Epub 2018 Mar 29. PMID: 29599413 PMCID: PMC6050085 [Available on 2019-07-15] read article


Robinson-McCarthy LR, McCarthy KR, Raaben M, Piccinotti S, Nieuwenhuis J, Stubbs SH, Bakkers MJG, Whelan SPJ. Reconstruction of the cell entry pathway of an extinct virus. PLoS Pathog. 2018 Aug 6;14(8):e1007123. doi: 10.1371/journal.ppat.1007123. eCollection 2018 Aug. PMID: 30080900 PMCID: PMC6095630 read article


Iampietro MJ, Larocca RA, Provine NM, Abbink P, Kang ZH, Bricault CA, Barouch DH. Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors. J Virol. 2018 May 14;92(11). pii: e00159-18. doi: 10.1128/JVI.00159-18. Print 2018 Jun 1. PMID: 29563285 PMCID: PMC5952169 read article


Badamchi-Zadeh A, Moynihan KD, Larocca RA, Aid M, Provine NM, Iampietro MJ, Kinnear E, Penaloza-MacMaster P, Abbink P, Blass E, Tregoning JS, Irvine DJ, Barouch DH. Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy. J Immunol. 2018 Nov 1;201(9):2744-2752. doi: 10.4049/jimmunol.1800885. Epub 2018 Sep 24. PMID: 30249811 PMCID: PMC6196294  read article


Otsuka Y, Schmitt K, Quinlan BD, Gardner MR, Alfant B, Reich A, Farzan M, Choe H. Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies. PLoS Pathog. 2018 Aug 20;14(8):e1007238. doi: 10.1371/journal.ppat.1007238. eCollection 2018 Aug. PMID: 30125330 PMCID: PMC6117093 read article


Raymond DD, Bajic G, Ferdman J, Suphaphiphat P, Settembre EC, Moody MA, Schmidt AG, Harrison SC. Raymond DD, Bajic G, Ferdman J, Suphaphiphat P, Settembre EC, Moody MA, Schmidt AG, Harrison SC. Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):168-173. doi: 10.1073/pnas.1715471115. Epub 2017 Dec 18. PMID: 29255041 PMCID: PMC5776812 read article


McCarthy KR, Watanabe A, Kuraoka M, Do KT, McGee CE, Sempowski GD, Kepler TB, Schmidt AG, Kelsoe G, Harrison SC. Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 2018 Jan 16;48(1):174-184.e9. doi: 10.1016/j.immuni.2017.12.009. PMID: 29343437 PMCID: PMC5810956 read article


Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 Nov 5;218(12):1954-1963. doi: 10.1093/infdis/jiy479. PMID: 30085241 PMCID: PMC6217727 read article


Strongin Z, Sharaf R, VanBelzen DJ, Jacobson JM, Connick E, Volberding P, Skiest DJ, Gandhi RT, Kuritzkes DR, O'Doherty U, Li JZ. Effect of Short-Term Antiretroviral Therapy Interruption on Levels of Integrated HIV DNA. J Virol. 2018 May 29;92(12). pii: e00285-18. doi: 10.1128/JVI.00285-18. Print 2018 Jun 15.PMID: 29593048 PMCID: PMC5974505 read article


Sharaf R, Lee GQ, Sun X, Etemad B, Aboukhater LM, Hu Z, Brumme ZL, Aga E, Bosch RJ, Wen Y, Namazi G, Gao C, Acosta EP, Gandhi RT, Jacobson JM, Skiest D, Margolis DM, Mitsuyasu R, Volberding P, Connick E, Kuritzkes DR, Lederman MM, Yu XG, Lichterfeld M, Li JZ. HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest. 2018 Aug 31;128(9):4074-4085. doi: 10.1172/JCI120549. Epub 2018 Aug 20. PMID: 30024859 PMCID: PMC6118642 read article


Bentley P, Tan MJA, McBride AA, White EA, Howley PM. The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA. J Virol. 2018 Jul 17;92(15). pii: e00356-18. doi: 10.1128/JVI.00356-18. Print 2018 Aug 1. PMID: 29848583 PMCID: PMC6052296 read article


Tarnita RM, Wilkie AR, DeCaprio JA. Contribution of DNA Replication to the FAM111A-Mediated Simian Virus 40 Host Range Phenotype. J Virol. 2018 Dec 10;93(1). pii: e01330-18. doi: 10.1128/JVI.01330-18. Print 2019 Jan 1. PMID: 30333173 PMCID: PMC6288344 read article


Wang LW, Trudeau SJ, Wang C, Gerdt C, Jiang S, Zhao B, Gewurz BE. Modulating Gene Expression in Epstein-Barr Virus (EBV)-Positive B Cell Lines with CRISPRa and CRISPRi. Curr Protoc Mol Biol. 2018 Jan 16;121:31.13.1-31.13.18. doi: 10.1002/cpmb.50. PMID: 29337370 PMCID: PMC5774230 read article


Jiang S, Wang LW, Walsh MJ, Trudeau SJ, Gerdt C, Zhao B, Gewurz BE. CRISPR/Cas9-Mediated Genome Editing in Epstein-Barr Virus-Transformed Lymphoblastoid B-Cell Lines. Curr Protoc Mol Biol. 2018 Jan 16;121:31.12.1-31.12.23. doi: 10.1002/cpmb.51. PMID: 29337376 read article


Wang MK, Ren T, Liu H, Lim SY, Lee K, Honko A, Zhou H, Dyall J, Hensley L, Gartin AK, Cunningham JM. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 Sep 28;14(9):e1007322. doi: 10.1371/journal.ppat.1007322. eCollection 2018 Sep. PMID: 30265711 PMCID: PMC6179309 read article


Liu H, Tian Y, Lee K, Krishnan P, Wang MK, Whelan S, Mevers E, Soloveva V, Dedic B, Liu X, Cunningham JM. Identification of Potent Ebola Virus Entry Inhibitors with Suitable Properties for in Vivo Studies. J Med Chem. 2018 Jul 3. doi: 10.1021/acs.jmedchem.8b00704. [Epub ahead of print] PMID: 29920098 read article


Wilkie AR, Sharma M, Pesola JM, Ericsson M, Fernandez R, Coen DM. A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress. J Virol. 2018 Feb 26;92(6). pii: e01849-17. doi: 10.1128/JVI.01849-17. Print 2018 Mar 15. PMID: 29298889 PMCID: PMC5827399 read article


Wu S, Liu QQ1, Gu W1, Ni SN1, Shi X1, Zhu ZY1 A Retrospective Analysis of Patients with Short Stature in the South of China between 2007 and 2015. Biomed Res Int. 2018 Dec 20;2018:5732694. doi: 10.1155/2018/5732694. eCollection 2018. PMID: 30671461 PMCID: PMC6317125  read article


Gumber S, Amancha PK, Yen PJ, Villinger F, Gabuzda D, Byrareddy SN. In vivo characterization of macrophage-tropic simian immunodeficiency virus molecular clones in rhesus macaques. J Neurovirol. 2018 Aug;24(4):411-419. doi: 10.1007/s13365-018-0628-2. Epub 2018 Mar 28. PMID: 29594984 PMCID: PMC6105460 [Available on 2019-08-01] read article


top

2017


Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, Brown M, Howley PM, Padi M, Washburn MP, DeCaprio JA. Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. PLoS Pathog. 2017 Oct 13;13(10):e1006668. doi: 10.1371/journal.ppat.1006668. eCollection 2017 Oct. PMID: 29028833 PMCID: PMC5640240 read article


Aid M, Abbink P, Larocca RA, Boyd M, Nityanandam R, Nanayakkara O, Martinot AJ, Moseley ET, Blass E, Borducchi EN, Chandrashekar A, Brinkman AL, Molloy K, Jetton D, Tartaglia LJ, Liu J, Best K, Perelson AS, De La Barrera RA, Lewis MG, Barouch DH. Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys. Cell. 2017 May 4;169(4):610-620.e14. doi: 10.1016/j.cell.2017.04.008. Epub 2017 Apr 27. PMID: 28457610 PMCID: PMC5426912 read article


Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH. Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens. Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26. PMID: 27899229 PMCID: PMC5147735 read article


Piai A, Dev J, Fu Q, Chou JJ. Stability and Water Accessibility of the Trimeric Membrane Anchors of the HIV-1 Envelope Spikes. J Am Chem Soc. 2017 Dec 27;139(51):18432-18435. doi: 10.1021/jacs.7b09352. Epub 2017 Dec 4. PMID: 29193965 PMCID: PMC5831154 read article


Franz KM, Kagan JC. Innate Immune Receptors as Competitive Determinants of Cell Fate. Mol Cell. 2017 Jun 15;66(6):750-760. doi: 10.1016/j.molcel.2017.05.009. PMID: 28622520 PMCID: PMC5503483 read article


Metsky HC, Matranga CB, Wohl S, Schaffner SF, Freije CA, Winnicki SM, West K, Qu J, Baniecki ML, Gladden-Young A, Lin AE, Tomkins-Tinch CH, Ye SH, Park DJ, Luo CY, Barnes KG, Shah RR, Chak B, Barbosa-Lima G, Delatorre E, Vieira YR, Paul LM, Tan AL, Barcellona CM, Porcelli MC, Vasquez C, Cannons AC, Cone MR, Hogan KN, Kopp EW, Anzinger JJ, Garcia KF, Parham LA, Ramírez RMG, Montoya MCM, Rojas DP, Brown CM, Hennigan S, Sabina B, Scotland S, Gangavarapu K, Grubaugh ND, Oliveira G, Robles-Sikisaka R, Rambaut A, Gehrke L, Smole S, Halloran ME, Villar L, Mattar S, Lorenzana I, Cerbino-Neto J, Valim C, Degrave W, Bozza PT, Gnirke A, Andersen KG, Isern S, Michael SF, Bozza FA,, Souza TML, Bosch I, Yozwiak NL, MacInnis BL, Sabeti PC. Zika virus evolution and spread in the Americas. Nature. 2017 Jun 15;546(7658):411-415. doi: 10.1038/nature22402. Epub 2017 May 24. PMID: 28538734 PMCID: PMC5563848  read article


Grubaugh ND, Ladner JT, Kraemer MUG, Dudas G, Tan AL, Gangavarapu K, Wiley MR, White S, Thézé J, Magnani DM, Prieto K, Reyes D, Bingham AM, Paul LM, Robles-Sikisaka R, Oliveira G, Pronty D, Barcellona CM, Metsky HC, Baniecki ML, Barnes KG, Chak B, Freije CA, Gladden-Young A, Gnirke A, Luo C, MacInnis B, Matranga CB, Park DJ, Qu J, Schaffner SF, Tomkins-Tinch C, West KL, Winnicki SM, Wohl S, Yozwiak NL, Quick J, Fauver JR, Khan K, Brent SE, Reiner RC Jr, Lichtenberger PN, Ricciardi MJ, Bailey VK, Watkins DI, Cone MR, Kopp EW th, Hogan KN, Cannons AC, Jean R, Monaghan AJ, Garry RF, Loman NJ, Faria NR, Porcelli MC, Vasquez C, Nagle ER, Cummings DAT, Stanek D, Rambaut A, Sanchez-Lockhart M, Sabeti PC, Gillis LD, Michael SF, Bedford T, Pybus OG, Isern S, Palacios G, Andersen KG. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. Nature. 2017 Jun 15;546(7658):401-405. doi: 10.1038/nature22400. Epub 2017 May 24. PMID: 28538723 PMCID: PMC5536180  read article


Gootenberg JS, Abudayyeh OO, Lee JW, Essletzbichler P, Dy AJ, Joung J, Verdine V, Donghia N, Daringer NM, Freije CA, Myhrvold C, Bhattacharyya RP, Livny J, Regev A, Koonin EV, Hung DT, Sabeti PC, Collins JJ, Zhang F. Nucleic acid detection with CRISPR-Cas13a/C2c2. Science. 2017 Apr 28;356(6336):438-442. doi: 10.1126/science.aam9321. Epub 2017 Apr 13. PMID: 28408723 PMCID: PMC5526198  read article


Fellinger CH, Gardner MR, Bailey CC, Farzan M. Simian Immunodeficiency Virus SIVmac239, but Not SIVmac316, Binds and Utilizes Human CD4 More Efficiently than Rhesus CD4. J Virol. 2017 Aug 24;91(18). pii: e00847-17. doi: 10.1128/JVI.00847-17. Print 2017 Sep 15. PMID: 28679752 PMCID: PMC5571245 read article


Davis-Gardner ME, Gardner MR, Alfant B, Farzan M. eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients. PLoS Pathog. 2017 Dec 18;13(12):e1006786. doi: 10.1371/journal.ppat.1006786. eCollection 2017 Dec. PMID: 29253851 PMCID: PMC5749896 read article


Gardner MR, Farzan M. Engineering antibody-like inhibitors to prevent and treat HIV-1 infection. Curr Opin HIV AIDS. 2017 May;12(3):294-301. doi: 10.1097/COH.0000000000000367. PMID: 28422793 PMCID: PMC5389584  read article


Gootenberg DB, Paer JM, Luévano JM, Kwon DS. HIV-associated changes in the enteric microbial community: potential role in loss of homeostasis and development of systemic inflammation. Curr Opin Infect Dis. 2017 Feb;30(1):31-43. doi: 10.1097/QCO.0000000000000341. PMID: 27922852 PMCID: PMC5325247 read article


Harden ME, Prasad N, Griffiths A, Munger K. Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins. MBio. 2017 Jan 3;8(1). pii: e02170-16. doi: 10.1128/mBio.02170-16. PMID: 28049151 PMCID: PMC5210503 read article


Harden ME, Munger K. Human papillomavirus molecular biology. Mutat Res Rev Mutat Res. 2017 Apr - Jun;772:3-12. doi: 10.1016/j.mrrev.2016.07.002. Epub 2016 Jul 5. PMID: 28528688 PMCID: PMC5500221 read article


Harden ME, Munger K. Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles. Virology. 2017 Aug;508:63-69. doi: 10.1016/j.virol.2017.05.005. Epub 2017 May 10. PMID: 28500882 PMCID: PMC5506845 read article


Harden ME, Munger K. Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins. Virology. 2017 Jul;507:192-198. doi: 10.1016/j.virol.2017.04.022. Epub 2017 Apr 24. PMID: 28448850 PMCID: PMC5499708 read article


Leviyang S, Griva I, Ita S, Johnson WE. A penalized regression approach to haplotype reconstruction of viral populations arising in early HIV/SIV infection. Bioinformatics. 2017 Aug 15;33(16):2455-2463. doi: 10.1093/bioinformatics/btx187. PMID: 28379346 PMCID: PMC5870767 read article


Ita S, Agostinho MR, Sullivan K, Yub Han S, Akleh R, Johnson WE, Fofana IBF. Analysis of SIVmac Envelope-Specific Antibodies Selected Through Phage Display. AIDS Res Hum Retroviruses. 2017 Aug;33(8):869-879. doi: 10.1089/AID.2016.0247. Epub 2017 Feb 16. PMID: 28075174 PMCID: PMC5749048 read article


Jennewein MF, Alter G. The Immunoregulatory Roles of Antibody Glycosylation. Trends Immunol. 2017 May;38(5):358-372. doi: 10.1016/j.it.2017.02.004. Epub 2017 Apr 3. PMID: 28385520 read article


Jennewein MF, Abu-Raya B, Jiang Y, Alter G, Marchant A. Transfer of maternal immunity and programming of the newborn immune system. Semin Immunopathol. 2017 Nov;39(6):605-613. doi: 10.1007/s00281-017-0653-x. Epub 2017 Oct 2. PMID: 28971246 read article


Jiang S, Zhou H, Liang J, Gerdt C, Wang C, Ke L, Schmidt SCS, Narita Y, Ma Y, Wang S, Colson T, Gewurz B, Li G, Kieff E, Zhao B. The Epstein-Barr Virus Regulome in Lymphoblastoid Cells. Cell Host Microbe. 2017 Oct 11;22(4):561-573.e4. doi: 10.1016/j.chom.2017.09.001. PMID: 29024646 PMCID: PMC5662195 read article


Wang W, Zhou J, Halambage UD, Jurado KA, Jamin AV, Wang Y, Engelman AN, Aiken C. Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein. J Virol. 2017 Apr 13;91(9). pii: e02155-16. doi: 10.1128/JVI.02155-16. Print 2017 May 1. PMID: 28202766 PMCID: PMC5391466 read article


Kim IS, Jenni S, Stanifer ML, Roth E, Whelan SP, van Oijen AM, Harrison SC. Mechanism of membrane fusion induced by vesicular stomatitis virus G protein. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E28-E36. doi: 10.1073/pnas.1618883114. Epub 2016 Dec 14. PMID: 27974607 PMCID: PMC5224367 read article


Knipe DM, Raja P, Lee J. Viral gene products actively promote latent infection by epigenetic silencing mechanisms. Curr Opin Virol. 2017 Apr;23:68-74. doi: 10.1016/j.coviro.2017.03.010. Epub 2017 Apr 14. PMID: 28415052 PMCID: PMC5475406 read article


Lim MY, O'Brien J, Paulo JA, Gygi SP. Improved Method for Determining Absolute Phosphorylation Stoichiometry Using Bayesian Statistics and Isobaric Labeling. Journal of Proteome Research. 2017 Nov 3;16(11):4217-4226. doi: 10.1021/acs.jproteome.7b00571. read article


Barnes KG, Kindrachuk J, Lin AE, Wohl S, Qu J, Tostenson SD, Dorman WR, Busby M, Siddle KJ, Luo CY, Matranga CB, Davey RT, Sabeti PC, Chertow DS. Evidence of Ebola Virus Replication and High Concentration in Semen of a Patient During Recovery. Clin Infect Dis. 2017 Oct 15;65(8):1400-1403. doi: 10.1093/cid/cix518. PMID: 28582513 PMCID: PMC5850519 read article


Metsky HC, Matranga CB, Wohl S, Schaffner SF, Freije CA, Winnicki SM, West K, Qu J, Baniecki ML, Gladden-Young A, Lin AE, Tomkins-Tinch CH, Ye SH, Park DJ, Luo CY, Barnes KG, Shah RR, Chak B, Barbosa-Lima G, Delatorre E, Vieira YR, Paul LM, Tan AL, Barcellona CM, Porcelli MC, Vasquez C, Cannons AC, Cone MR, Hogan KN, Kopp EW, Anzinger JJ, Garcia KF, Parham LA, Ramírez RMG, Montoya MCM, Rojas DP, Brown CM, Hennigan S, Sabina B, Scotland S, Gangavarapu K, Grubaugh ND, Oliveira G, Robles-Sikisaka R, Rambaut A, Gehrke L, Smole S, Halloran ME, Villar L, Mattar S, Lorenzana I, Cerbino-Neto J, Valim C, Degrave W, Bozza PT, Gnirke A, Andersen KG, Isern S, Michael SF, Bozza FA, Souza TML, Bosch I, Yozwiak NL, MacInnis BL, Sabeti PC. Zika virus evolution and spread in the Americas. Nature. 2017 Jun 15;546(7658):411-415. doi: 10.1038/nature22402. Epub 2017 May 24. PMID: 28538734 PMCID: PMC5563848 read article


Julg B, Liu PT, Wagh K, Fischer WM, Abbink P, Mercado NB, Whitney JB, Nkolola JP, McMahan K, Tartaglia LJ, Borducchi EN, Khatiwada S, Kamath M, LeSuer JA, Seaman MS, Schmidt SD, Mascola JR, Burton DR, Korber BT, Barouch DH. Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail. Sci Transl Med. 2017 Sep 20;9(408). pii: eaao4235. doi: 10.1126/scitranslmed.aao4235. PMID: 28931655 PMCID: PMC5747528 read article


Brown EP, Dowell KG, Boesch AW, Normandin E, Mahan AE, Chu T, Barouch DH, Bailey-Kellogg C, Alter G, Ackerman ME. Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles. J Immunol Methods. 2017 Apr;443:33-44. doi: 10.1016/j.jim.2017.01.010. Epub 2017 Feb 3. PMID: 28163018 PMCID: PMC5333794 read article


Madani N, Princiotto AM, Zhao C, Jahanbakhshsefidi F, Mertens M, Herschhorn A, Melillo B, Smith AB 3rd, Sodroski J. Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds. J Virol. 2017 Jan 18;91(3). pii: e01880-16. doi: 10.1128/JVI.01880-16. Print 2017 Feb 1. PMID: 27881646 PMCID: PMC5244334 read article


Kurt-Jones EA, Orzalli MH, Knipe DM. Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease. Adv Anat Embryol Cell Biol. 2017;223:49-75. doi: 10.1007/978-3-319-53168-7_3. PMID: 28528439 read article


Orzalli MH, Kagan JC. Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection. Trends Cell Biol. 2017 Nov;27(11):800-809. doi: 10.1016/j.tcb.2017.05.007. Epub 2017 Jun 19. PMID: 28642032 PMCID: PMC5653411 read article


Ning J, Wakimoto H, Peters C, Martuza RL, Rabkin SD. Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma. J Natl Cancer Inst. 2017 Mar 1;109(3):1-13. doi: 10.1093/jnci/djw229. PMID: 28376211 PMCID: PMC6059185 read article


Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH. Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens. Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26. PMID: 27899229 PMCID: PMC5147735 read article


Pyle JD, Keeling PJ, Nibert ML. Amalga-like virus infecting Antonospora locustae, a microsporidian pathogen of grasshoppers, plus related viruses associated with other arthropods. Virus Res. 2017 Apr 2;233:95-104. doi: 10.1016/j.virusres.2017.02.015. Epub 2017 Mar 4. PMID: 28267607 PMCID: PMC5489755 read article


Rahmberg AR, Rajakumar PA, Billingsley JM, Johnson RP. Dynamic Modulation of Expression of Lentiviral Restriction Factors in Primary CD4+ T Cells following Simian Immunodeficiency Virus Infection. J Virol. 2017 Mar 13;91(7). pii: e02189-16. doi: 10.1128/JVI.02189-16. Print 2017 Apr 1. PMID: 28100613 PMCID: PMC5355611 read article


Liu Y, Pan J, Jenni S, Raymond DD, Caradonna T, Do KT, Schmidt AG, Harrison SC, Grigorieff N. CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. J Mol Biol. 2017 Jun 16;429(12):1829-1839. doi: 10.1016/j.jmb.2017.05.011. Epub 2017 May 12. PMID: 28506635 PMCID: PMC5535819 read article


Sharaf RR, Li JZ. The Alphabet Soup of HIV Reservoir Markers. Curr HIV/AIDS Rep. 2017 Apr;14(2):72-81. doi: 10.1007/s11904-017-0355-y. PMID: 28401492 PMCID: PMC5519144 read article


Groppelli E, Levy HC, Sun E, Strauss M, Nicol C, Gold S, Zhuang X, Tuthill TJ, Hogle JM, Rowlands DJ. Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes. PLoS Pathog. 2017 Feb 6;13(2):e1006197. doi: 10.1371/journal.ppat.1006197. eCollection 2017 Feb. PMID: 28166307 PMCID: PMC5325612 read article


Thorpe LM, Spangle JM, Ohlson CE, Cheng H, Roberts TM, Cantley LC, Zhao JJ. PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7095-7100. doi: 10.1073/pnas.1704706114. Epub 2017 Jun 19. PMID: 28630349 PMCID: PMC5502636 read article


Ersing I, Nobre L, Wang LW, Soday L, Ma Y, Paulo JA, Narita Y, Ashbaugh CW, Jiang C, Grayson NE, Kieff E, Gygi SP, Weekes MP, Gewurz BE. A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells. Cell Rep. 2017 May 16;19(7):1479-1493. doi: 10.1016/j.celrep.2017.04.062. PMID: 28514666 PMCID: PMC5446956 read article


Wang LW, Jiang S, Gewurz BE. Epstein-Barr Virus LMP1-Mediated Oncogenicity. J Virol. 2017 Oct 13;91(21). pii: e01718-16. doi: 10.1128/JVI.01718-16. Print 2017 Nov 1. PMID: 28835489 PMCID: PMC5640852 read article


Wang MK, Lim SY, Lee SM, Cunningham JM. Biochemical Basis for Increased Activity of Ebola Glycoprotein in the 2013-16 Epidemic. Cell Host Microbe. 2017 Mar 8;21(3):367-375. doi: 10.1016/j.chom.2017.02.002. Epub 2017 Feb 23. PMID: 28238624 PMCID: PMC5735838 read article


Wang X, Moazed D. DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation. Science. 2017 Mar 16. pii: eaaj2114. doi: 10.1126/science.aaj2114. PMID: 28302794 read article


Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, Brown M, Howley PM, Padi M, Washburn MP, DeCaprio JA. Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. PLoS Pathog. 2017 Oct 13;13(10):e1006668. doi: 10.1371/journal.ppat.1006668. eCollection 2017 Oct. PMID: 29028833 PMCID: PMC5640240 read article


top

2016


Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA. Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation. PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat.1006020. eCollection 2016 Nov. PMID: 27880818 PMCID: PMC5120958 read article


Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt. Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26. PMID: 27237051 PMCID: PMC4912424 read article


Larocca RA, Provine NM, Aid M, Iampietro MJ, Borducchi EN, Badamchi-Zadeh A, Abbink P, Ng'ang'a D, Bricault CA, Blass E, Penaloza-MacMaster P, Stephenson KE, Barouch DH. Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function. Sci Immunol. 2016 Nov;1(5). pii: eaaf7643. doi: 10.1126/sciimmunol.aaf7643. Epub 2016 Nov 4. read article


Wheeler LA, Trifonova RT, Vrbanac V, Barteneva NS, Liu X, Bollman B, Onofrey L, Mulik S, Ranjbar S, Luster AD, Tager AM, Lieberman J. TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice. Cell Rep. 2016 May 24;15(8):1715-27. doi: 10.1016/j.celrep.2016.04.048. Epub 2016 May 12. PMID: 27184854 PMCID: PMC4881429 read article


Choudhury R, Bonacci T, Arceci A, Lahiri D, Mills CA, Kernan JL, Branigan TB, DeCaprio JA, Burke DJ, Emanuele MJ. APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry. Cell Rep. 2016 Sep 20;16(12):3359-72. doi: 10.1016/j.celrep.2016.08.058. PMID: 27653696  read article


Larocca RA, Abbink P, Peron JP, Zanotto PM, Iampietro MJ, Badamchi-Zadeh A, Boyd M, Ng'ang'a D, Kirilova M, Nityanandam R, Mercado NB, Li Z, Moseley ET, Bricault CA, Borducchi EN, Giglio PB, Jetton D, Neubauer G, Nkolola JP, Maxfield LF, De La Barrera RA, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH. Vaccine protection against Zika virus from Brazil. Nature. 2016 Aug 25;536(7617):474-8. Epub 2016 Jun 28. PMID: 27355570 PMCID: PMC5003703 read article


Abbink P, Larocca RA, De La Barrera RA, Bricault CA, Moseley ET, Boyd M, Kirilova M, Li Z, Ng'ang'a D, Nanayakkara O, Nityanandam R, Mercado NB, Borducchi EN, Agarwal A, Brinkman AL, Cabral C, Chandrashekar A, Giglio PB, Jetton D, Jimenez J, Lee BC, Mojta S, Molloy K, Shetty M, Neubauer GH, Stephenson KE, Peron JP, Zanotto PM, Misamore J, Finneyfrock B, Lewis MG, Alter G, Modjarrad K, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH. Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys. Science. 2016 Sep 9;353(6304):1129-32. doi: 10.1126/science.aah6157. Epub 2016 Aug 4. PMID: 27492477 PMCID: PMC5237380 read article


Stephenson KE, Neubauer GH, Bricault CA, Shields J, Bayne M, Reimer U, Pawlowski N, Knaute T, Zerweck J, Seaman MS, Rosenberg ES, Barouch DH. Antibody Responses After Analytic Treatment Interruption in Human Immunodeficiency Virus-1-Infected Individuals on Early Initiated Antiretroviral Therapy. Open Forum Infect Dis. 2016 May 19;3(2):ofw100. doi: 10.1093/ofid/ofw100. eCollection 2016 Apr. PMID: 27419172 PMCID: PMC4943535 read article


Larocca RA, Provine NM, Aid M, Iampietro MJ, Borducchi EN, Badamchi-Zadeh A, Abbink P, Ng'ang'a D, Bricault CA, Blass E, Penaloza-MacMaster P, Stephenson KE, Barouch DH. Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function. Sci Immunol. 2016 Nov;1(5). pii: eaaf7643. doi: 10.1126/sciimmunol.aaf7643. Epub 2016 Nov 4. PMID: 28239679 PMCID: PMC5322800  read article


Provine NM, Badamchi-Zadeh A, Bricault CA, Penaloza-MacMaster P, Larocca RA, Borducchi EN, Seaman MS, Barouch DH. Transient CD4+ T Cell Depletion Results in Delayed Development of Functional Vaccine-Elicited Antibody Responses. J Virol. 2016 Apr 14;90(9):4278-4288. doi: 10.1128/JVI.00039-16. Print 2016 May. PMID: 26865713 PMCID: PMC4836333 read article


Clark MJ, Miduturu C, Schmidt AG, Zhu X, Pitts JD, Wang J, Potisopon S, Zhang J, Wojciechowski A, Hann Chu JJ, Gray NS, Yang PL. GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein. Cell Chem Biol. 2016 Apr 21;23(4):443-52. doi: 10.1016/j.chembiol.2016.03.010. PMID: 27105280 PMCID: PMC4865888 read article


Maier KE, Jangra RK, Shieh KR, Cureton DK, Xiao H, Snapp EL, Whelan SP, Chandran K, Levy M. A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry. Mol Ther Nucleic Acids. 2016 May 24;5:e321. doi: 10.1038/mtna.2016.32. PMID: 27219515  read article


Chou YY, Cuevas C, Carocci M, Stubbs SH, Ma M, Cureton DK, Chao L, Evesson F, He K, Yang PL, Whelan SP, Ross SR, Kirchhausen T, Gaudin R. Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol. 2016 Apr 14;90(9):4494-4510. doi: 10.1128/JVI.00103-16. Print 2016 May. PMID: 26912630 PMCID: PMC4836360  read article


Dev J, Park D, Fu Q, Chen J, Ha HJ, Ghantous F, Herrmann T, Chang W, Liu Z, Frey G, Seaman MS, Chen B, Chou JJ. Structural basis for membrane anchoring of HIV-1 envelope spike. Science. 2016 Jul 8;353(6295):172-5. doi: 10.1126/science.aaf7066. Epub 2016 Jun 23. PMID: 27338706 PMCID: PMC5085267  read article


Zhao L, Wang S, Du L, Dev J, Zhou L, Liu Z, Chou JJ, OuYang B. Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride. Protein Cell. 2016 Apr;7(4):300-4. doi: 10.1007/s13238-016-0256-7. No abstract available. PMID: 26951497 PMCID: 26951497 read article


Piai A, Fu Q, Dev J, Chou JJ. Optimal Bicelle Size q for Solution NMR Studies of the Protein Transmembrane Partition. Chemistry. 2017 Jan 26;23(6):1361-1367. doi: 10.1002/chem.201604206. Epub 2016 Dec 22. PMID: 27747952 PMCID: PMC5272838 read article


Durbin AF, Wang C, Marcotrigiano J, Gehrke L. RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling. MBio. 2016 Sep 20;7(5). pii: e00833-16. doi: 10.1128/mBio.00833-16. PMID: 27651356 PMCID: PMC5030355 read article


Raymond DD, Stewart SM, Lee J, Ferdman J, Bajic G, Do KT, Ernandes MJ, Suphaphiphat P, Settembre EC, Dormitzer PR, Del Giudice G, Finco O, Kang TH,Ippolito GC, Georgiou G, Kepler TB, Haynes BF, Moody MA, Liao HX, Schmidt AG, Harrison SC. Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nat Med. 2016 Dec;22(12):1465-1469. doi: 10.1038/nm.4223. Epub 2016 Nov 7. PMID: 27820604 PMCID: PMC5485662 read article


Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, Lemmin TM, Leung S, Louder MK, McDaniel JR, Narpala S, Pancera M, Stuckey J, Wu X, Yang Y, Zhang B, Zhou T; NISC Comparative Sequencing Program, Mullikin JC, Baxa U, Georgiou G, McDermott AB, Bonsignori M, Haynes BF, Moore PL, Morris L, Lee KK, Shapiro L, Mascola JR, Kwong PD. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat Struct Mol Biol. 2016 Jan;23(1):81-90. doi: 10.1038/nsmb.3144. Epub 2015 Dec 21. PMID: 26689967 PMCID: PMC4833398 read article


Gardner MR, Fellinger CH, Prasad NR, Zhou AS, Kondur HR, Joshi VR, Quinlan BD, Farzan M. CD4-Induced Antibodies Promote Association of the HIV-1 Envelope Glycoprotein with CD4-Binding Site Antibodies. J Virol. 2016 Aug 12;90(17):7822-32. doi: 10.1128/JVI.00803-16. Print 2016 Sep 1. PMID: 27334589 PMCID: PMC4988152 read article


Monaco CL, Gootenberg DB, Zhao G, Handley SA, Ghebremichael MS, Lim ES, Lankowski A, Baldridge MT, Wilen CB, Flagg M, Norman JM, Keller BC, Luévano JM, Wang D, Boum Y, Martin JN, Hunt PW, Bangsberg DR, Siedner MJ, Kwon DS, Virgin HW. Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome. Cell Host Microbe. 2016 Mar 9;19(3):311-22. doi: 10.1016/j.chom.2016.02.011. PMID: 26962942 PMCID: PMC4821831  read article


Larocca RA, Abbink P, Peron JP, Zanotto PM, Iampietro MJ, Badamchi-Zadeh A, Boyd M, Ng'ang'a D, Kirilova M, Nityanandam R, Mercado NB, Li Z, Moseley ET, Bricault CA, Borducchi EN, Giglio PB, Jetton D, Neubauer G, Nkolola JP, Maxfield LF, De La Barrera RA, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH. Vaccine protection against Zika virus from Brazil. Nature. 2016 Aug 25;536(7617):474-8. PMID: 27355570 PMCID: PMC5003703 read article


Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim M, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH. Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens. Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26. PMID: 27899229 PMCID: PMC5147735 read article


Larocca RA, Provine NM, Aid M, Iampietro MJ, Borducchi EN, Badamchi-Zadeh A, Abbink P, Ng'ang'a D, Bricault CA, Blass E, Penaloza-MacMaster P, Stephenson KE, Barouch DH. Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function. Sci Immunol. 2016 Nov;1(5). pii: eaaf7643. doi: 10.1126/sciimmunol.aaf7643. Epub 2016 Nov 4. PMID: 28239679 PMCID: PMC5322800 read article


Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, Alter G. Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. PLoS Pathog. 2016 Jun 2;12(6):e1005694. doi: 10.1371/journal.ppat.1005694. eCollection 2016 Jun. PMID: 27253391 PMCID: PMC4890747 read article


Raja P, Lee JS, Pan D, Pesola JM, Coen DM, Knipe DM. A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin. MBio. 2016 May 17;7(3). pii: e00633-16. doi: 10.1128/mBio.00633-16. PMID: 27190217 PMCID: PMC4895110 read article


Lee JS, Raja P, Knipe DM. Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection. MBio. 2016 Jan 12;7(1):e02007-15. doi: 10.1128/mBio.02007-15. PMID: 26758183 PMCID: PMC4725016 read article


Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA. Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation. PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat.1006020. eCollection 2016 Nov 23. PMID: 27880818 PMCID: PMC5120958 read article


Penaloza MacMaster P, Shields JL, Alayo QA, Cabral C, Jimenez J, Mondesir J, Chandrashekar A, Cabral JM, Lim MY, Iampietro MJ, Provine NM, Bricault CA, Seaman M, Orlinger K, Aspoeck A, Fuhrmann G, Lilja AE, Monath T, Mangeat B, Pinschewer DD, Barouch DH. Development of novel replication-defective lymphocytic choriomeningitis virus vectors expressing SIV antigens. Vaccine. 2017 Jan 3;35(1):1-9. doi: 10.1016/j.vaccine.2016.11.063. Epub 2016 Nov 26. read article


Lu LL, Chung AW, Rosebrock TR, Ghebremichael M, Yu WH, Grace PS, Schoen MK, Tafesse F, Martin C, Leung V, Mahan AE, Sips M, Kumar MP, Tedesco J, Robinson H, Tkachenko E, Draghi M, Freedberg KJ, Streeck H, Suscovich TJ, Lauffenburger DA, Restrepo BI, Day C, Fortune SM, Alter G. A Functional Role for Antibodies in Tuberculosis. Cell. 2016 Oct 6;167(2):433-443.e14. doi: 10.1016/j.cell.2016.08.072. Epub 2016 Sep 22. PMID: 27667685 PMCID: PMC5526202 read article


Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, Alter G. Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. PLoS Pathog. 2016 Mar 16;12(3):e1005456. doi: 10.1371/journal.ppat.1005456. eCollection 2016 Mar. PMID: 26982805 PMCID: PMC4794126 read article


Mahan AE, Jennewein MF, Suscovich T, Dionne K, Tedesco J, Chung AW, Streeck H, Pau M, Schuitemaker H, Francis D, Fast P, Laufer D, Walker BD, Baden L, Barouch DH, Alter G. Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. PLoS Pathog. 2016 Jun 2;12(6):e1005694. doi: 10.1371/journal.ppat.1005694. eCollection 2016 Jun. PMID: 27253391 PMCID: PMC4890747 read article


Sarkar A, Hou HW, Mahan AE, Han J, Alter G. Multiplexed Affinity-Based Separation of Proteins and Cells Using Inertial Microfluidics. Sci Rep. 2016 Mar 30;6:23589. doi: 10.1038/srep23589. PMID: 27026280 PMCID: PMC4812309 read article


Barnett BE, Staupe RP, Odorizzi PM, Palko O, Tomov VT, Mahan AE, Gunn B, Chen D, Paley MA, Alter G, Reiner SL, Lauer GM, Teijaro JR, Wherry EJ. Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection. J Immunol. 2016 Aug 15;197(4):1017-22. doi: 10.4049/jimmunol.1500368. Epub 2016 Jul 18. PMID: 27430722 PMCID: PMC4975981 read article


McCarthy KR, Johnson WE, Kirmaier A. Phylogeny and History of the Lost SIV from Crab-Eating Macaques: SIVmfa. PLoS One. 2016 Jul 14;11(7):e0159281. doi: 10.1371/journal.pone.0159281. eCollection 2016. PMID: 27415779 PMCID: PMC4944941 read article


Orzalli MH, Broekema NM, Knipe DM. Relative Contributions of Herpes Simplex Virus 1 ICP0 and vhs to Loss of Cellular IFI16 Vary in Different Human Cell Types. J Virol. 2016 Aug 26;90(18):8351-9. doi: 10.1128/JVI.00939-16. Print 2016 Sep 15. PMID: 27412599 PMCID: PMC5008076 read article


Orzalli MH, Kagan JC. A one-protein signaling pathway in the innate immune system. Sci Immunol. 2016 Aug 19;1(2):eaah6184. doi: 10.1126/sciimmunol.aah6184. Epub 2016 Aug 19. PMID: 28783697 read article


Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA. Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation. PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat. 1006020.


Piccinotti S, Whelan SP. Rabies Internalizes into Primary Peripheral Neurons via Clathrin Coated Pits and Requires Fusion at the Cell Body. PLoS Pathog. 2016 Jul 27;12(7):e1005753. doi: 10.1371/journal.ppat.1005753. eCollection 2016 Jul. PMID: 27463226 PMCID: PMC4963122 read article


Provine NM, Larocca RA, Aid M, Penaloza-MacMaster P, Badamchi-Zadeh A, Borducchi EN, Yates KB, Abbink P, Kirilova M, Ng'ang'a D, Bramson J, Haining WN, Barouch DH. Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells. J Immunol. 2016 Sep 1;197(5):1809-22. doi: 10.4049/jimmunol.1600591. Epub 2016 Jul 22. PMID: 27448585 PMCID: PMC4991249  read article


Penaloza-MacMaster P, Alayo QA, Ra J, Provine NM, Larocca R, Lee B, Barouch DH. Inhibitory receptor expression on memory CD8 T cells following Ad vector immunization. Vaccine. 2016 Sep 22;34(41):4955-4963. doi: 10.1016/j.vaccine.2016.08.048. Epub 2016 Aug 24. PMID: 27566899 PMCID: PMC5038157 read article


Larocca RA, Provine NM, Aid M, Iampietro MJ, Borducchi EN, Badamchi-Zadeh A, Abbink P, Ng'ang'a D, Bricault CA, Blass E, Penaloza-MacMaster P, Stephenson KE, Barouch DH. Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function. Sci Immunol. 2016 Nov;1(5). pii: eaaf7643. doi: 10.1126/sciimmunol.aaf7643. Epub 2016 Nov 4. PMID: 28239679 PMCID: PMC5322800 read article


Provine NM, Badamchi-Zadeh A, Bricault CA, Penaloza-MacMaster P, Larocca RA, Borducchi EN, Seaman MS, Barouch DH. Transient CD4+ T Cell Depletion Results in Delayed Development of Functional Vaccine-Elicited Antibody Responses. J Virol. 2016 Apr 14;90(9):4278-4288. doi: 10.1128/JVI.00039-16. Print 2016 May. PMID: 26865713 PMCID: PMC4836333 read article


Nibert ML, Pyle JD, Firth AE. A +1 ribosomal frameshifting motif prevalent among plant amalgaviruses. Virology. 2016 Nov;498:201-208. doi: 10.1016/j.virol.2016.07.002. Epub 2016 Sep 4. PMID: 27596539 PMCID: PMC5052127 read article


Gardner MR, Fellinger CH, Prasad NR, Zhou AS, Kondur HR, Joshi VR, Quinlan BD, Farzan M. CD4-Induced Antibodies Promote Association of the HIV-1 Envelope Glycoprotein with CD4-Binding Site Antibodies. J Virol. 2016 Aug 12;90(17):7822-32. doi: 10.1128/JVI.00803-16. Print 2016 Sep 1. PMID: 27334589 PMCID: PMC4988152 read article


Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Cottle L, Zhang XC, Makhema J, Mills LA, Panchia R, Faesen S, Eron J, Gallant J, Havlir D, Swindells S, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano DD, Essex M, Hudelson SE, Redd AD, Fleming TR; HPTN 052 Study Team. Antiretroviral Therapy for the Prevention of HIV-1 Transmission. N Engl J Med. 2016 Sep 1;375(9):830-9. doi: 10.1056/NEJMoa1600693. Epub 2016 Jul 18. PMID: 27424812 PMCID: PMC5049503  read article


Robinson LR, Whelan SP. Infectious Entry Pathway Mediated by the Human Endogenous Retrovirus K Envelope Protein. J Virol. 2016 Jan 20;90(7):3640-9. doi: 10.1128/JVI.03136-15. PMID: 26792739 PMCID: PMC4794671 read article


Russo BC, Stamm LM, Raaben M, Kim CM, Kahoud E, Robinson LR, Bose S, Queiroz AL, Herrera BB, Baxt LA, Mor-Vaknin N, Fu Y, Molina G, Markovitz DM, Whelan SP, Goldberg MB. Intermediate filaments enable pathogen docking to trigger type 3 effector translocation. Nat Microbiol. 2016 Mar 7;1:16025. doi: 10.1038/nmicrobiol.2016.25. PMID: 27572444 PMCID: PMC5006386 read article


Kuraoka M, Schmidt AG, Nojima T, Feng F, Watanabe A, Kitamura D, Harrison SC, Kepler TB, Kelsoe G. Complex Antigens Drive Permissive Clonal Selection in Germinal Centers. Immunity. 2016 Mar 15;44(3):542-552. doi: 10.1016/j.immuni.2016.02.010. Epub 2016 Mar 3. PMID: 26948373 PMCID: PMC4794380  read article


Raymond DD, Stewart SM, Lee J, Ferdman J, Bajic G, Do KT, Ernandes MJ, Suphaphiphat P, Settembre EC, Dormitzer PR, Del Giudice G, Finco O, Kang TH, Ippolito GC, Georgiou G, Kepler TB, Haynes BF, Moody MA, Liao HX, Schmidt AG, Harrison SC. Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nat Med. 2016 Dec;22(12):1465-1469. doi: 10.1038/nm.4223. Epub 2016 Nov 7. read article


Sharaf R, Mempel TR, Murooka TT. Visualizing the Behavior of HIV-Infected T Cells In Vivo Using Multiphoton Intravital Microscopy. Methods Mol Biol. 2016;1354:189-201. doi: 10.1007/978-1-4939-3046-3_13. PMID: 26714713  read article


Soh TK, Whelan SP. Correction for Soh and Whelan, Tracking the Fate of Genetically Distinct Vesicular Stomatitis Virus Matrix Proteins Highlights the Role for Late Domains in Assembly. J Virol. 2016 May 27;90(12):5847. doi: 10.1128/JVI.00633-16. Print 2016 Jun 15. PMID: 27234347 PMCID: PMC4886790 read article


Yuzugullu H, Von T, Thorpe LM, Walker SR, Roberts TM, Frank DA, Zhao JJ. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016 Sep 20;2:16030. doi: 10.1038/celldisc.2016.30. eCollection 2016. PMID: 27672444 PMCID: PMC5029543 read article


Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM. Getting to and through the inner nuclear membrane during herpesvirus nuclear egress. Curr Opin Cell Biol. 2017 Jun;46:9-16. doi: 10.1016/j.ceb.2016.12.007. Epub 2017 Jan 10. PMID: 28086162 PMCID: PMC5503802 read article


Wilkie AR, Lawler JL, Coen DM. A Role for Nuclear F-Actin Induction in Human Cytomegalovirus Nuclear Egress. MBio. 2016 Aug 23;7(4). pii: e01254-16. doi: 10.1128/mBio.01254-16. PMID: 27555312 PMCID: PMC4999551
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top

2015


Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18. PMID: 25707797 PMCID: PMC4352131 read article


Penaloza-MacMaster P, Provine NM, Blass E, Barouch DH. CD4 T Cell Depletion Substantially Augments the Rescue Potential of PD-L1 Blockade for Deeply Exhausted CD8 T Cells. J Immunol. 2015 Aug 1;195(3):1054-63. doi: 10.4049/jimmunol.1403237. Epub 2015 Jun 26. PMID: 26116499 PMCID: PMC4505958
 read article


Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH. Antigen-specific NK cell memory in rhesus macaques. Nat Immunol. 2015 Sep;16(9):927-32. doi: 10.1038/ni.3227. Epub 2015 Jul 20. PMID: 26193080
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Abbink P, Maxfield LF, Ng'ang'a D, Borducchi EN, Iampietro MJ, Bricault CA, Teigler JE, Blackmore S, Parenteau L, Wagh K, Handley SA, Zhao G, Virgin HW, Korber B, Barouch DH. Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors. J Virol. 2015 Feb;89(3):1512-22. doi: 10.1128/JVI.02950-14. Epub 2014 Nov 19. PMID: 25410856 PMCID: PMC4300752  read article


Bricault CA, Kovacs JM, Nkolola JP, Yusim K, Giorgi EE, Shields JL, Perry J, Lavine CL, Cheung A, Ellingson-Strouss K, Rademeyer C, Gray GE, Williamson C, Stamatatos L, Seaman MS, Korber BT, Chen B, Barouch DH. A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component. J Virol. 2015 Mar;89(5):2507-19. doi: 10.1128/JVI.03331-14. Epub 2014 Dec 24. PMID: 25540368 PMCID: PMC4325749 read article


Conwell, SE, White, AE, Harper, JW, Knipe, DM. Identification of TRIM27 as a Novel Degradation Target of Herpes Simplex Virus 1 ICP0. J Virol. 2015 Jan;89(1):220-9. doi: 10.1128/JVI.02635-14. Epub 2014 Oct 15.PMID: 25320289 PMCID: PMC4301158  read article


Davis ME, Gack MU. Ubiquitination in the antiviral immune response. Virology. 2015 May;479-480:52-65. doi: 10.1016/j.virol.2015.02.033. Epub 2015 Mar 7. PMID: 25753787 PMCID: PMC4774549  read article


Dev J, Brüschweiler S, Ouyang B, Chou JJ. Transverse relaxation dispersion of the p7 membrane channel from hepatitis C virus reveals conformational breathing. J Biomol NMR. 2015 Apr;61(3-4):369-78. doi: 10.1007/s10858-015-9912-0. Epub 2015 Feb 28. PMID: 25724842 PMCID: 25724842 read article


Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS,Louder MK, McKee K, O'Dell S, Schmidt SD, Tran L, Yang Z, Druz A, Luongo TS, Moquin S, Srivatsan S, Yang Y, Zhang B, Zheng A, Pancera M,Kirys T, Georgiev IS, Gindin T, Peng HP, Yang AS; NISC Comparative Sequencing Program, Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF, Casazza JP, Connors M, Corti D, Lanzavecchia A, Sattentau QJ, Weiss RA, West AP Jr, Bjorkman PJ, Scheid JF, Nussenzweig MC, Shapiro L, Mascola JR, Kwong PD. Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell. 2015 Jun 4;161(6):1280-92. doi: 10.1016/j.cell.2015.05.007. Epub 2015 May 21. PMID: 26004070 PMCID: PMC4683157
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Doria-Rose NA, Bhiman JN, Roark RS, Schramm CA, Gorman J, Chuang GY, Pancera M, Cale EM, Ernandes MJ, Louder MK, Asokan M, Bailer RT, Druz A, Fraschilla IR, Garrett NJ, Jarosinski M, Lynch RM, McKee K, O'Dell S, Pegu A, Schmidt SD, Staupe RP, Sutton MS, Wang K, Wibmer CK, Haynes BF, Abdool-Karim S, Shapiro L, Kwong PD, Moore PL, Morris L, Mascola JR. New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency. J Virol. 2015 Oct 14;90(1):76-91. doi: 10.1128/JVI.01791-15. Print 2016 Jan 1. PMID: 26468542 PMCID: PMC4702551 read article


Chow J, Franz KM, Kagan JC. PRRs are watching you: Localization of innate sensing and signaling regulators. Virology. 2015 May;479-480:104-9. doi: 10.1016/j.virol.2015.02.051. Epub 2015 Mar 20. PMID: 25800355 PMCID: PMC4424080 read article


Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M.AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18. PMID: 25707797 PMCID: PMC4352131 read article


von Bredow B, Arias JF, Heyer LN, Gardner MR, Farzan M, Rakasz EG, Evans DT. Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity. J Virol. 2015 Oct;89(20):10648-55. doi: 10.1128/JVI.01911-15. Epub 2015 Aug 12. PMID: 26269175 PMCID: PMC4580155 read article


Cao Y, Sarria I, Fehlhaber KE, Kamasawa N, Orlandi C, James KN, Hazen JL, Gardner MR, Farzan M, Lee A, Baker S, Baldwin K, Sampath AP, Martemyanov KA. Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision. Neuron. 2015 Sep 23;87(6):1248-1260. doi: 10.1016/j.neuron.2015.09.002. PMID: 26402607 PMCID: PMC4583715 read article


Herrman M, Mühe J, Quink C, Wang F. Epstein-Barr Virus gp350 Can Functionally Replace the Rhesus Lymphocryptovirus Major Membrane Glycoprotein and Does Not Restrict Infection of Rhesus Macaques. J Virol. 2015 Nov 11;90(3):1222-30. doi: 10.1128/JVI.02531-15. Print 2016 Feb 1. PMID: 26559839 PMCID: PMC4719629 read article


Schmidt SC, Jiang S, Zhou H, Willox B, Holthaus AM, Kharchenko PV, Johannsen
EC, Kieff E, Zhao B. Epstein-Barr virus nuclear antigen 3A partially coincides
with EBNA3C genome-wide and is tethered to DNA through BATF complexes. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):554-9. doi: 10.1073/pnas.1422580112. Epub 2014 Dec 24. PubMed PMID: 25540416; PubMed Central PMCID: PMC4299249.
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Zhou H, Schmidt SC, Jiang S, Willox B, Bernhardt K, Liang J, Johannsen EC,
Kharchenko P, Gewurz BE, Kieff E, Zhao B. Epstein-Barr virus oncoprotein
super-enhancers control B cell growth. Cell Host Microbe. 2015 Feb
11;17(2):205-16. doi: 10.1016/j.chom.2014.12.013. Epub 2015 Jan 29. PubMed PMID:
25639793.
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Fontana J, Jurado KA, Cheng N, Ly NL, Fuchs JR, Gorelick RJ, Engelman AN, Steven AC. Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation. J Virol. 2015 Oct;89(19):9765-80. doi: 10.1128/JVI.01522-15. Epub 2015 Jul 15. PMID: 26178982 PMCID: PMC4577894 read article


Knipe DM, Raja P, Lee JS. Clues to mechanisms of herpesviral latent infection and potential cures. Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):11993-4. doi: 10.1073/pnas.1516224112. Epub 2015 Sep 21. PMID: 26392531 PMCID: PMC4593103  read article


Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H. Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9010-5. doi: 10.1073/pnas.1511140112. Epub 2015 Jul 6. PMID: 26150520 PMCID: PMC4517201 read article


Kugelman JR, Sanchez-Lockhart M, Andersen KG, Gire S, Park DJ, Sealfon R, Lin AE, Wohl S, Sabeti PC, Kuhn JH, Palacios GF. Evaluation of the potential impact of Ebola virus genomic drift on the efficacy of sequence-based candidate therapeutics. MBio. 2015 Jan 20;6(1). pii: e02227-14. doi: 10.1128/mBio.02227-14. PMID: 25604787 PMCID: PMC4313914 read article


Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF, Sabeti PC. Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone. Cell. 2015 Jun 18;161(7):1516-26. doi: 10.1016/j.cell.2015.06.007. PMID: 26091036 PMCID: PMC4503805 read article


Andersen KG, Shapiro BJ, Matranga CB, Sealfon R, Lin AE, Moses LM, Folarin OA, Goba A, Odia I, Ehiane PE, Momoh M, England EM, Winnicki S, Branco LM, Gire SK, Phelan E, Tariyal R, Tewhey R, Omoniwa O, Fullah M, Fonnie R, Fonnie M, Kanneh L, Jalloh S, Gbakie M, Saffa S, Karbo K, Gladden AD, Qu J, Stremlau M, Nekoui M, Finucane HK, Tabrizi S, Vitti JJ, Birren B, Fitzgerald M, McCowan C, Ireland A, Berlin AM, Bochicchio J, Tazon-Vega B, Lennon NJ, Ryan EM, Bjornson Z, Milner DA Jr, Lukens AK, Broodie N, Rowland M, Heinrich M, Akdag M, Schieffelin JS, Levy D, Akpan H, Bausch DG, Rubins K, McCormick JB, Lander ES, Günther S, Hensley L, Okogbenin S; Viral Hemorrhagic Fever Consortium., Schaffner SF, Okokhere PO, Khan SH, Grant DS, Akpede GO, Asogun DA, Gnirke A, Levin JZ, Happi CT, Garry RF, Sabeti PC. Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus. Cell. 2015 Aug 13;162(4):738-50. doi: 10.1016/j.cell.2015.07.020. PMID: 26276630 PMCID: PMC4537774 read article


Chung AW, Kumar MP, Arnold KB, Yu WH, Schoen MK, Dunphy LJ, Suscovich TJ, Frahm N, Linde C, Mahan AE, Hoffner M, Streeck H, Ackerman ME, McElrath MJ, Schuitemaker H, Pau MG, Baden LR, Kim JH, Michael NL, Barouch DH, Lauffenburger DA, Alter G. Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology. Cell. 2015 Nov 5;163(4):988-98. doi: 10.1016/j.cell.2015.10.027. PMID: 26544943 PMCID: PMC5490491 read article


Brown EP, Normandin E, Osei-Owusu NY, Mahan AE, Chan YN, Lai JI, Vaccari M, Rao M, Franchini G, Alter G, Ackerman ME. Microscale purification of antigen-specific antibodies. J Immunol Methods. 2015 Oct;425:27-36. doi: 10.1016/j.jim.2015.06.005. Epub 2015 Jun 12. PMID: 26078040 PMCID: PMC4604017 read article


Mahan AE, Tedesco J, Dionne K, Baruah K, Cheng HD, De Jager PL, Barouch DH, Suscovich T, Ackerman M, Crispin M, Alter G. A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis. J Immunol Methods. 2015 Feb;417:34-44. doi: 10.1016/j.jim.2014.12.004. Epub 2014 Dec 15. PMID: 25523925 PMCID: PMC5054724 read article


McCarthy KR, Kirmaier A, Autissier P, Johnson WE. Evolutionary and Functional Analysis of Old World Primate TRIM5 Reveals the Ancient Emergence of Primate Lentiviruses and Convergent Evolution Targeting a Conserved Capsid Interface. PLoS Pathog. 2015 Aug 20;11(8):e1005085. doi: 10.1371/journal.ppat.1005085. eCollection 2015 Aug. PMID: 26291613 PMCID: PMC4546234 read article


Mefford ME, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5. Virology. 2015 Jul;481:210-22. doi: 10.1016/j.virol.2015.01.032. Epub 2015 Mar 20. PMID: 25797607 PMCID: PMC4437837  read article


Orzalli MH, Broekema NM, Diner BA, Hancks DC, Elde NC, Cristea IM, Knipe DM. cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1773-81. doi: 10.1073/pnas.1424637112. Epub 2015 Mar 23. PMID: 25831530 PMCID: PMC4394261 read article


Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, Barouch DH. Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection. Science. 2015 Jan 16;347(6219):278-82. doi: 10.1126/science.aaa2148. PMID: 25593185 PMCID: PMC4382081 read article


Penaloza-MacMaster P, Provine NM, Blass E, Barouch DH. CD4 T Cell Depletion Substantially Augments the Rescue Potential of PD-L1 Blockade for Deeply Exhausted CD8 T Cells. J Immunol. 2015 Aug 1;195(3):1054-63. doi: 10.4049/jimmunol.1403237. Epub 2015 Jun 26. PMID: 26116499 PMCID: PMC4505958 read article


Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 2015 Mar 5;519(7541):87-91. doi: 10.1038/nature14264. Epub 2015 Feb 18. PMID: 25707797 PMCID: PMC4352131 read article


Schafer JL, Ries M, Guha N, Connole M, Colantonio AD, Wiertz EJ, Wilson NA, Kaur A, Evans DT. Suppression of a Natural Killer Cell Response by Simian Immunodeficiency Virus Peptides. PLoS Pathog. 2015 Sep 2;11(9):e1005145. doi: 10.1371/journal.ppat.1005145. eCollection 2015 Sep. PMID: 26333068 PMCID: PMC4557930 read article


Hölzemer A, Thobakgale CF, Jimenez Cruz CA, Garcia-Beltran WF, Carlson JM, van Teijlingen NH, Mann JK, Jaggernath M, Kang SG, Körner C, Chung AW, Schafer JL, Evans DT, Alter G, Walker BD, Goulder PJ, Carrington M, Hartmann P, Pertel T, Zhou R, Ndung'u T, Altfeld M. Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa. PLoS Med. 2015 Nov 17;12(11):e1001900; discussion e1001900. doi: 10.1371/journal.pmed.1001900. eCollection 2015 Nov. PMID: 26575988 PMCID: PMC4648589 read article


Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, von Andrian UH, Barouch DH. Antigen-specific NK cell memory in rhesus macaques. Nat Immunol. 2015 Sep;16(9):927-32. doi: 10.1038/ni.3227. Epub 2015 Jul 20. PMID: 26193080 PMCID: PMC4545390 read article


Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Correction: Sequential conformational rearrangements in flavivirus membrane fusion. Elife. 2015 May 18;4. doi: 10.7554/eLife.08656. PMID: 25984968 PMCID: PMC4434378 read article


Schmidt AG, Therkelsen MD, Stewart S, Kepler TB, Liao HX, Moody MA, Haynes BF, Harrison SC. Viral receptor-binding site antibodies with diverse germline origins. Cell. 2015 May 21;161(5):1026-1034. doi: 10.1016/j.cell.2015.04.028. Epub 2015 May 7. PMID: 25959776 PMCID: PMC4441819 read article


Schmidt AG, Do KT, McCarthy KR, Kepler TB, Liao HX, Moody MA, Haynes BF, Harrison SC. Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site. Cell Rep. 2015 Dec 29;13(12):2842-50. doi: 10.1016/j.celrep.2015.11.063. Epub 2015 Dec 17. PMID: 26711348 PMCID: PMC4698027 read article


Xu H, Schmidt AG, O'Donnell T, Therkelsen MD, Kepler TB, Moody MA, Haynes BF, Liao HX, Harrison SC, Shaw DE. Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage. Proteins. 2015 Apr;83(4):771-80. doi: 10.1002/prot.24745. Epub 2015 Feb 28. PMID: 25524709 PMCID: PMC4368477 read article


Murooka TT, Sharaf RR, Mempel TR. Large Syncytia in Lymph Nodes Induced by CCR5-Tropic HIV-1. AIDS Res Hum Retroviruses. 2015 May;31(5):471-2. doi: 10.1089/aid.2014.0378. Epub 2015 Apr 2. PMID: 25835064 PMCID: PMC4426294 read article


Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F. HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell Responses. J Virol. 2015 Dec 9;90(5):2208-20. doi: 10.1128/JVI.02278-15. PMID: 26656715 PMCID: PMC4810720 read article


Soh TK, Whelan SP. Tracking the Fate of Genetically Distinct Vesicular Stomatitis Virus Matrix Proteins Highlights the Role for Late Domains in Assembly. J Virol. 2015 Dec;89(23):11750-60. doi: 10.1128/JVI.01371-15. Epub 2015 Sep 2. PMID: 26339059 PMCID: PMC4645316 read article


Penaloza-MacMaster P, Barber DL, Wherry EJ, Provine NM, Teigler JE, Parenteau L, Blackmore S, Borducchi EN, Larocca RA, Yates KB, Shen H, Haining WN, Sommerstein R, Pinschewer DD, Ahmed R, Barouch DH. Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection. Science. 2015 Jan 16;347(6219):278-82. doi: 10.1126/science.aaa2148. PMID: 25593185 PMCID: PMC4382081 read article


Abbink P, Maxfield LF, Ng'ang'a D, Borducchi EN, Iampietro MJ, Bricault CA, Teigler JE, Blackmore S, Parenteau L, Wagh K, Handley SA, Zhao G, Virgin HW, Korber B, Barouch DH. Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors. J Virol. 2015 Feb;89(3):1512-22. doi: 10.1128/JVI.02950-14. Epub 2014 Nov 19. PMID: 25410856 PMCID: PMC4300752 read article


Thorpe LM, Yuzugullu H, Zhao JJ. PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting. Nat Rev Cancer. 2015 Jan;15(1):7-24. doi: 10.1038/nrc3860. PMID: 25533673 PMCID: PMC4384662 read article


Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, Clayton LK, Bronson R, Roberts TM, Gritsman K, Zhao JJ. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nat Commun. 2015 Oct 7;6:8501. doi: 10.1038/ncomms9501. PMID: 26442967 PMCID: PMC4598950 read article


top

2014


Li Q, Zeng M, Duan L, Voss JE, Smith AJ, Pambuccian S, Shang L, Wietgrefe S, Southern PJ, Reilly CS, Skinner PJ, Zupancic ML, Carlis JV, Piatak M Jr, Waterman D, Reeves RK, Masek-Hammerman K, Derdeyn CA, Alpert MD, Evans DT, Kohler H, Müller S, Robinson J, Lifson JD, Burton DR, Johnson RP, Haase AT. Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry. J Immunol. 2014 Sep 15;193(6):3113-25. doi: 10.4049/jimmunol.1400820. Epub 2014 Aug 18. PMID: 25135832 PMCID: PMC4157131  read article


Li SS, Gilbert PB, Tomaras GD, Kijak G, Ferrari G, Thomas R, Pyo CW, Zolla-Pazner S, Montefiori D, Liao HX, Nabel G, Pinter A, Evans DT, Gottardo R, Dai JY, Janes H, Morris D, Fong Y, Edlefsen PT, Li F, Frahm N, Alpert MD, Prentice H, Rerks-Ngarm S, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Robb ML, O'Connell RJ, Haynes BF, Michael NL, Kim JH, McElrath MJ, Geraghty DE. FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial. J Clin Invest. 2014 Sep;124(9):3879-90. doi: 10.1172/JCI75539. Epub 2014 Aug 8. PMID: 25105367 PMCID: PMC4151214 read article


Nkolola JP, Bricault CA, Cheung A, Shields J, Perry J, Kovacs JM, Giorgi E, van Winsen M, Apetri A, Brinkman-van der Linden EC, Chen B, Korber B, Seaman MS, Barouch DH. Characterization and immunogenicity of a novel mosaic M HIV-1 gp140 trimer. J Virol. 2014 Sep 1;88(17):9538-52. doi: 10.1128/JVI.01739-14. Epub 2014 Jun 25. PMID: 24965452 PMCID: PMC4136343 read article


Yan Z, Bryant KF, Gregory SM, Angelova M, Dreyfus DH, Zhao XZ, Coen DM, Burke TR Jr, Knipe DM. HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesviruses. MBio. 2014 Jul 1;5(4):e01318-14. doi: 10.1128/mBio.01318-14. PMID: 24987091 PMCID: PMC4161245  read article


Davis ME, Wang MK, Rennick LJ, Full F, Gableske S, Mesman AW, Gringhuis SI, Geijtenbeek TB, Duprex WP, Gack MU. Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5. Cell Host Microbe. 2014 Jul 9;16(1):19-30. doi: 10.1016/j.chom.2014.06.007 PMID: 25011105 PMCID: PMC4120867 read article


Mesman AW, Zijlstra-Willems EM, Kaptein TM, de Swart RL, Davis ME, Ludlow M, Duprex WP, Gack MU, Gringhuis SI, Geijtenbeek TB. Measles virus suppresses RIG-I-like receptor activation in dendritic cells via DC-SIGN-mediated inhibition of PP1 phosphatases. Cell Host Microbe. 2014 Jul 9;16(1):31-42. doi: 10.1016/j.chom.2014.06.008. PMID: 25011106 PMCID: PMC4159752 read article


Chiang JJ, Davis ME, Gack MU. Regulation of RIG-I-like receptor signaling by host and viral proteins. Cytokine Growth Factor Rev. 2014 Oct;25(5):491-505. doi: 10.1016/j.cytogfr.2014.06.005. Epub 2014 Jun 21. PMID: 25023063 read article


Davis ME, Wang MK, Rennick LJ, Full F, Gableske S, Mesman AW, Gringhuis SI, Geijtenbeek TB, Duprex WP, Gack MU. Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5. Cell Host Microbe. 2014 Jul 9;16(1):19-30. doi: 10.1016/j.chom.2014.06.007. PMID: 25011105 PMCID: PMC4120867 read article


Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MU. The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25. Sci Signal. 2014 Jan 7;7(307):ra3. doi: 10.1126/scisignal.2004577. PMID: 24399297 PMCID: PMC4008495  read article


De León Vázquez E, Juillard F, Rosner B, Kaye KM. A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistence. Virology. 2014 Jan 5;448:344-55. doi: 10.1016/j.virol.2013.10.026. Epub 2013 Nov 12. PMID: 24314665 PMCID: PMC3857964  read article


Sun Q, Tsurimoto T, Juillard F, Li L, Li S, De León Vázquez E, Chen S, Kaye K. Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11816-21. doi: 10.1073/pnas.1404219111. Epub 2014 Jul 28. PMID: 25071216 PMCID: PMC4136584 read article


Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin AF, Boulant S, Gehrke L, Cossart P, Kagan JC. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014 Aug;15(8):717-26. doi: 10.1038/ni.2915. PMID: 24952503 PMCID: PMC4106986 read article


Ellis LC, Koralnik IJ. JC virus nucleotides 376-396 are critical for VP1 capsid protein expression. J Neurovirol. 2015 Dec;21(6):671-8. doi: 10.1007/s13365-014-0278-y. Epub 2014 Aug 21. PMID: 25142442 PMCID: PMC4336641 read article


Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, Druz A, Garrett NJ, Hoi KH, Kong R, Louder MK, Longo NS, McKee K, Nonyane M, O'Dell S, Roark RS, Rudicell RS, Schmidt SD, Sheward DJ, Soto C, Wibmer CK, Yang Y, Zhang Z; NISC Comparative Sequencing Program, Mullikin JC, Binley JM, Sanders RW, Wilson IA, Moore JP, Ward AB, Georgiou G, Williamson C, Abdool Karim SS, Morris L, Kwong PD, Shapiro L, Mascola JR. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 2014 May 1;509(7498):55-62. doi: 10.1038/nature13036. Epub 2014 Mar 2. PMID: 24590074 PMCID: PMC4395007 read article


Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin AF, Boulant S, Gehrke L, Cossart P, Kagan JC. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014 Aug;15(8):717-26. doi: 10.1038/ni.2915. PMID: 24952503 PMCID: PMC4106986 read article


Franz KM, Kagan JC. Finding a needle in a haystack of needles - a productive hunt for interferon stimulated genes with antiviral activity. Immunol Cell Biol. 2014 Mar;92(3):205-7. doi: 10.1038/icb.2013.108. Epub 2014 Jan 14. PMID: 24418815 PMCID: PMC3960321 read article


Quinlan BD, Joshi VR, Gardner MR, Ebrahimi KH, Farzan M. A double-mimetic peptide efficiently neutralizes HIV-1 by bridging the CD4- and coreceptor-binding sites of gp120. J Virol. 2014 Mar;88(6):3353-8. doi: 10.1128/JVI.03800-13. Epub 2014 Jan 3. PMID: 24390333 PMCID: PMC3957931 read article


Guth CA, Sodroski J. Contribution of PDZD8 to stabilization of the human immunodeficiency virus type 1 capsid. J Virol. 2014 May;88(9):4612-23. doi: 10.1128/JVI.02945-13. Epub 2014 Feb 19. PMID: 24554657 PMCID: PMC3993830 read article


Bailey CC, Zhong G, Huang IC, Farzan M. IFITM-Family Proteins: The Cell's First Line of Antiviral Defense. Annu Rev Virol. 2014 Nov 1;1:261-283. PMID: 25599080 PMCID: PMC4295558
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Williams DE, Wu WL, Grotefend CR, Radic V, Chung C, Chung YH, Farzan M, Huang IC. IFITM3 polymorphism rs12252-C restricts influenza A viruses. PLoS One. 2014 Oct 14;9(10):e110096. doi: 10.1371/journal.pone.0110096. eCollection 2014.PMID: 25314048 PMCID: PMC4196997
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Warren CJ, Griffin LM, Little AS, Huang IC, Farzan M, Pyeon D. The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS One. 2014 May 14;9(5):e96579. doi: 10.1371/journal.pone.0096579. eCollection 2014. PMID: 24827144 PMCID: PMC4020762 read article


Abbink P, Maxfield LF, Ng'ang'a D, Borducchi EN, Iampietro MJ, Bricault CA, Teigler JE, Blackmore S, Parenteau L, Wagh K, Handley SA, Zhao G, Virgin HW, Korber B, Barouch DH. Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors. J Virol. 2015 Feb;89(3):1512-22. doi: 10.1128/JVI.02950-14. Epub 2014 Nov 19. PMID: 25410856 PMCID: PMC4300752 read article


Jiang S, Willox B, Zhou H, Holthaus AM, Wang A, Shi TT, Maruo S, Kharchenko PV, Johannsen EC, Kieff E, Zhao B. Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):421-6. doi: 10.1073/pnas.1321704111. Epub 2013 Dec 16. PMID: 24344258 PMCID: PMC3890834 read article


Zhao B, Barrera LA, Ersing I, Willox B, Schmidt SC, Greenfeld H, Zhou H, Mollo
SB, Shi TT, Takasaki K,
Jiang S, Cahir-McFarland E, Kellis M, Bulyk ML, Kieff E,
Gewurz BE. The NF-κB genomic landscape in lymphoblastoid B cells. Cell Rep. 2014
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Li M, Jurado KA, Lin S, Engelman A, Craigie R. Engineered hyperactive integrase for concerted HIV-1 DNA integration. PLoS One. 2014 Aug 13;9(8):e105078. doi: 10.1371/journal.pone.0105078. eCollection 2014. PMID: 25119883 PMCID: PMC4132020 read article


Slaughter A, Jurado KA, Deng N, Feng L, Kessl JJ, Shkriabai N, Larue RC, Fadel HJ, Patel PA, Jena N, Fuchs JR, Poeschla E, Levy RM, Engelman A, Kvaratskhelia M. The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase. Retrovirology. 2014 Nov 25;11:100. doi: 10.1186/s12977-014-0100-1. PMID: 25421939 PMCID: PMC4251946 read article


Li H, Stephenson KE, Kang ZH, Lavine CL, Seaman MS, Barouch DH. Common features of mucosal and peripheral antibody responses elicited by candidate HIV-1 vaccines in rhesus monkeys. J Virol. 2014 Nov;88(22):13510-5. doi: 10.1128/JVI.02095-14. Epub 2014 Sep 10. PMID: 25210178 PMCID: PMC4249108 read article


Penaloza-MacMaster P, Teigler JE, Obeng RC, Kang ZH, Provine NM, Parenteau L, Blackmore S, Ra J, Borducchi EN, Barouch DH. Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens. J Virol. 2014 Jun;88(11):6243-54. doi: 10.1128/JVI.00406-14. Epub 2014 Mar 19. PMID: 24648461 PMCID: PMC4093883 read article


Gelev V, Zabolotny JM, Lange M, Hiromura M, Yoo SW, Orlando JS, Kushnir A, Horikoshi N, Paquet E, Bachvarov D, Schaffer PA, Usheva A. A new paradigm for transcription factor TFIIB functionality. Sci Rep. 2014 Jan 20;4:3664. doi: 10.1038/srep03664. PMID: 24441171 PMCID: PMC3895905  read article


Lee AS, Burdeinick-Kerr R, Whelan SP. A genome-wide small interfering RNA screen identifies host factors required for vesicular stomatitis virus infection. J Virol. 2014 Aug;88(15):8355-60. doi: 10.1128/JVI.00642-14. Epub 2014 May 14. PMID: 24829348 PMCID: PMC4135952 read article


Lee AS, Burdeinick-Kerr R, Whelan SP. A genome-wide small interfering RNA screen identifies host factors required for vesicular stomatitis virus infection. J Virol. 2014 Aug;88(15):8355-60. doi: 10.1128/JVI.00642-14. Epub 2014 May 14. PMID: 24829348 PMCID: PMC4135952 https://www.ncbi.nlm.nih.gov/pubmed/24829348 read article


Hill JM, Quenelle DC, Cardin RD, Vogel JL, Clement C, Bravo FJ, Foster TP, Bosch-Marce M, Raja P, Lee JS, Bernstein DI, Krause PR, Knipe DM, Kristie TM. Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes. Sci Transl Med. 2014 Dec 3;6(265):265ra169. doi: 10.1126/scitranslmed.3010643. PMID: 25473037 PMCID: PMC4416407 read article


Coote P, Leigh KE, Yu TY, Khaneja N, Wagner G, Arthanari H. A new broadband homonuclear mixing pulse for NMR with low applied power. J Chem Phys. 2014 Jul 14;141(2):024201. doi: 10.1063/1.4885853. PMID: 25028012 PMCID: PMC4104837 read article


Chung AW, Ghebremichael M, Robinson H, Brown E, Choi I, Lane S, Dugast AS, Schoen MK, Rolland M, Suscovich TJ, Mahan AE, Liao L, Streeck H, Andrews C, Rerks-Ngarm S, Nitayaphan S, de Souza MS, Kaewkungwal J, Pitisuttithum P, Francis D, Michael NL, Kim JH, Bailey-Kellogg C, Ackerman ME, Alter G. Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines. Sci Transl Med. 2014 Mar 19;6(228):228ra38. doi: 10.1126/scitranslmed.3007736. PMID: 24648341  read article


Matreyek KA, Wang W, Serrao E, Singh PK, Levin HL, Engelman A. Host and viral determinants for MxB restriction of HIV-1 infection. Retrovirology. 2014 Oct 25;11:90. doi: 10.1186/s12977-014-0090-z. PMID: 25348155 PMCID: PMC4213484 read article


Fribourgh JL, Nguyen HC, Matreyek KA, Alvarez FJD, Summers BJ, Dewdney TG, Aiken C, Zhang P, Engelman A, Xiong Y. Structural insight into HIV-1 restriction by MxB. Cell Host Microbe. 2014 Nov 12;16(5):627-638. doi: 10.1016/j.chom.2014.09.021. Epub 2014 Oct 9. PMID: 25312384 PMCID: PMC4252739 read article


McCarthy KR, Johnson WE. Plastic proteins and monkey blocks: how lentiviruses evolved to replicate in the presence of primate restriction factors. PLoS Pathog. 2014 Apr 17;10(4):e1004017. doi: 10.1371/journal.ppat.1004017. eCollection 2014. PMID: 24743473 PMCID: PMC3990706 read article


Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D. Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 2014 Jun;458-459:53-68. doi: 10.1016/j.virol.2014.03.024. Epub 2014 May 8. PMID: 24928039 PMCID: PMC4112485 read article


Orzalli MH, Knipe DM. Cellular sensing of viral DNA and viral evasion mechanisms. Annu Rev Microbiol. 2014;68:477-92. doi: 10.1146/annurev-micro-091313-103409. Epub 2014 Jun 16. PMID: 25002095 PMCID: PMC4348004 read article


Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC. A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 2014 Feb 13;156(4):705-16. doi: 10.1016/j.cell.2014.01.019. PMID: 24529375 PMCID: PMC3951743 read article


Maertens GN, Cook NJ, Wang W, Hare S, Gupta SS, Öztop I, Lee K, Pye VE, Cosnefroy O, Snijders AP, KewalRamani VN, Fassati A, Engelman A, Cherepanov P. Structural basis for nuclear import of splicing factors by human Transportin 3. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2728-33. doi: 10.1073/pnas.1320755111. Epub 2014 Jan 21. PMID: 24449914 PMCID: PMC3932936 read article


Provine NM, Larocca RA, Penaloza-MacMaster P, Borducchi EN, McNally A, Parenteau LR, Kaufman DR, Barouch DH. Longitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses. J Immunol. 2014 Jun 1;192(11):5214-25. doi: 10.4049/jimmunol.1302806. Epub 2014 Apr 28. PMID: 24778441 PMCID: PMC4025612 read article


Penaloza-MacMaster P, Teigler JE, Obeng RC, Kang ZH, Provine NM, Parenteau L, Blackmore S, Ra J, Borducchi EN, Barouch DH. Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens. J Virol. 2014 Jun;88(11):6243-54. doi: 10.1128/JVI.00406-14. Epub 2014 Mar 19. PMID: 24648461 PMCID: PMC4093883 read article


Teigler JE, Penaloza-MacMaster P, Obeng R, Provine NM, Larocca RA, Borducchi EN, Barouch DH. Hexon hypervariable region-modified adenovirus type 5 (Ad5) vectors display reduced hepatotoxicity but induce T lymphocyte phenotypes similar to Ad5 vectors. Clin Vaccine Immunol. 2014 Aug;21(8):1137-44. doi: 10.1128/CVI.00207-14. Epub 2014 Jun 18. PMID: 24943382 PMCID: PMC4135912 read article


Quinlan BD, Joshi VR, Gardner MR, Ebrahimi KH, Farzan M. A double-mimetic peptide efficiently neutralizes HIV-1 by bridging the CD4- and coreceptor-binding sites of gp120. J Virol. 2014 Mar;88(6):3353-8. doi: 10.1128/JVI.03800-13. Epub 2014 Jan 3. PMID: 24390333 PMCID: PMC3957931 read article


French CA, Rahman S, Walsh EM, Kühnle S, Grayson AR, Lemieux ME, Grunfeld N, Rubin BP, Antonescu CR, Zhang S, Venkatramani R, Dal Cin P, Howley PM. NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism. Cancer Discov. 2014 Aug;4(8):928-41. doi: 10.1158/2159-8290.CD-14-0014. Epub 2014 May 29. PMID: 24875858 PMCID: PMC4125436 read article


van Teijlingen NH, Hölzemer A, Körner C, García-Beltrán WF, Schafer JL, Fadda L, Suscovich TJ, Brander C, Carrington M, Evans DT, van Baarle D, Altfeld M. Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function. AIDS. 2014 Jun 19;28(10):1399-408. doi: 10.1097/QAD.0000000000000284. PMID: 24785948 PMCID: PMC4453925 read article


Schafer JL, Colantonio AD, Neidermyer WJ, Dudley DM, Connole M, O'Connor DH, Evans DT. KIR3DL01 recognition of Bw4 ligands in the rhesus macaque: maintenance of Bw4 specificity since the divergence of apes and Old World monkeys. J Immunol. 2014 Feb 15;192(4):1907-17. doi: 10.4049/jimmunol.1302883. Epub 2014 Jan 22. PMID: 24453246 PMCID: PMC4162532  read article


Chao LH, Klein DE, Schmidt AG, Peña JM, Harrison SC. Sequential conformational rearrangements in flavivirus membrane fusion. Elife. 2014 Dec 5;3:e04389. doi: 10.7554/eLife.04389. PMID: 25479384 PMCID: PMC4293572 read article


Fera D, Schmidt AG, Haynes BF, Gao F, Liao HX, Kepler TB, Harrison SC. Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10275-80. doi: 10.1073/pnas.1409954111. Epub 2014 Jun 30. PMID: 24982157 PMCID: PMC4104889  read article


Pereyra F, Heckerman D, Carlson JM, Kadie C, Soghoian DZ, Karel D, Goldenthal A, Davis OB, DeZiel CE, Lin T, Peng J, Piechocka A, Carrington M, Walker BD. HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes. J Virol. 2014 Nov;88(22):12937-48. doi: 10.1128/JVI.01004-14. Epub 2014 Aug 27. PMID: 25165115 PMCID: PMC4249072 read article


Gaiha GD, McKim KJ, Woods M, Pertel T, Rohrbach J, Barteneva N, Chin CR, Liu D, Soghoian DZ, Cesa K, Wilton S, Waring MT, Chicoine A, Doering T, Wherry EJ, Kaufmann DE, Lichterfeld M, Brass AL, Walker BD. Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis. Immunity. 2014 Dec 18;41(6):1001-12. doi: 10.1016/j.immuni.2014.12.011. Epub 2014 Dec 8. PMID: 25526311 PMCID: PMC4312487  read article


Jae LT, Raaben M, Herbert AS, Kuehne AI, Wirchnianski AS, Soh TK, Stubbs SH, Janssen H, Damme M, Saftig P, Whelan SP, Dye JM, Brummelkamp TR. Virus entry. Lassa virus entry requires a trigger-induced receptor switch. Science. 2014 Jun 27;344(6191):1506-10. doi: 10.1126/science.1252480. PMID: 24970085 PMCID: PMC4239993  read article


Teigler JE, Kagan JC, Barouch DH. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol. 2014 Sep;88(18):10354-63. doi: 10.1128/JVI.00936-14. Epub 2014 Jul 2. PMID: 24991003 PMCID: PMC4178875 read article


Penaloza-MacMaster P, Teigler JE, Obeng RC, Kang ZH, Provine NM, Parenteau L, Blackmore S, Ra J, Borducchi EN, Barouch DH. Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens. J Virol. 2014 Jun;88(11):6243-54. doi: 10.1128/JVI.00406-14. Epub 2014 Mar 19. PMID: 24648461 PMCID: PMC4093883 read article


Teigler JE, Penaloza-MacMaster P, Obeng R, Provine NM, Larocca RA, Borducchi EN, Barouch DH. Hexon hypervariable region-modified adenovirus type 5 (Ad5) vectors display reduced hepatotoxicity but induce T lymphocyte phenotypes similar to Ad5 vectors. Clin Vaccine Immunol. 2014 Aug;21(8):1137-44. doi: 10.1128/CVI.00207-14. Epub 2014 Jun 18.PMID: 24943382 PMCID: PMC4135912 read article


Teigler JE, Phogat S, Franchini G, Hirsch VM, Michael NL, Barouch DH. The canarypox virus vector ALVAC induces distinct cytokine responses compared to the vaccinia virus-based vectors MVA and NYVAC in rhesus monkeys. J Virol. 2014 Feb;88(3):1809-14. doi: 10.1128/JVI.02386-13. Epub 2013 Nov 20. PMID: 24257612 PMCID: PMC3911591 read article


Csibi A, Lee G, Yoon SO, Tong H, Ilter D, Elia I, Fendt SM, Roberts TM, Blenis J. The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation. Curr Biol. 2014 Oct 6;24(19):2274-80. doi: 10.1016/j.cub.2014.08.007. Epub 2014 Sep 11. PMID: 25220053 PMCID: PMC4190129 read article


Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D. Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission. J Virol. 2014 May;88(9):5014-28. doi: 10.1128/JVI.02785-13. Epub 2014 Feb 19. PMID: 24554659 PMCID: PMC3993815 read article


Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D. Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 2014 Jun;458-459:53-68. doi: 10.1016/j.virol.2014.03.024. Epub 2014 May 8. PMID: 24928039 PMCID: PMC4112485 read article


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2013


Berrios C, Jung J, Primi B, Wang M, Pedamallu C, Duke F, Marcelus C, Cheng J, Garcea RL, Meyerson M, DeCaprio JA. Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors. J Virol. 2015 Jan;89(1):857-62. doi: 10.1128/JVI.02328-14. Epub 2014 Oct 15. PMID: 25320321 PMCID: PMC4301141 read article


Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM. Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4492-501. doi: 10.1073/pnas.1316194110. Epub 2013 Nov 6. PMID: 24198334 PMCID: PMC3839728 read article


Lee K, Ren T, Côté M, Gholamreza B, Misasi J, Bruchez A, Cunningham J. Inhibition of Ebola Virus Infection: Identification of Niemann-Pick C1 as the Target by Optimization of a Chemical Probe. ACS Med Chem Lett. 2013 Feb 14;4(2):239-243. Epub 2012 Dec 19. PMID: 23526644 PMCID: PMC3601783 read article


Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM. Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4492-501. doi: 10.1073/pnas.1316194110. Epub 2013 Nov 6. PMID: 24198334 PMCID: PMC3839728 read article


OuYang B, Xie S, Berardi MJ, Zhao X, Dev J, Yu W, Sun B, Chou JJ. Unusual architecture of the p7 channel from hepatitis C virus. Nature. 2013 Jun 27;498(7455):521-5. doi: 10.1038/nature12283. Epub 2013 Jun 5. PMID: 23739335 PMCID: 23739335 read article


Quinlan BD, Gardner MR, Joshi VR, Chiang JJ, Farzan M. Direct expression and validation of phage-selected pepti de variants in mammalian cells. J Biol Chem. 2013 Jun 28;288(26):18803-10. doi: 10.1074/jbc.M113.452839. Epub 2013 May 10. PMID: 23667257 PMCID: PMC3696656 read article


Bailey CC, Kondur HR, Huang IC, Farzan M. Interferon-induced transmembrane protein 3 is a type II transmembrane protein. J Biol Chem. 2013 Nov 8;288(45):32184-93. doi: 10.1074/jbc.M113.514356. Epub 2013 Sep 25. PMID: 24067232 PMCID:PMC3820858
 read article


Mudhasani R, Tran JP, Retterer C, Radoshitzky SR, Kota KP, Altamura LA, Smith JM, Packard BZ, Kuhn JH, Costantino J, Garrison AR, Schmaljohn CS, Huang IC, Farzan M, Bavari S. IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus. J Virol. 2013 Aug;87(15):8451-64. doi: 10.1128/JVI.03382-12. Epub 2013 May 29. PMID: 23720721 PMCID: PMC3719792 read article


Brudner M, Karpel M, Lear C, Chen L, Yantosca LM, Scully C, Sarraju A, Sokolovska A, Zariffard MR, Eisen DP, Mungall BA, Kotton DN, Omari A, Huang IC, Farzan M, Takahashi K, Stuart L, Stahl GL, Ezekowitz AB, Spear GT, Olinger GG, Schmidt EV, Michelow IC. Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. PLoS One. 2013;8(4):e60838. doi: 10.1371/journal.pone.0060838. Epub 2013 Apr 2. PMID: 23573288 PMCID:PMC3614905
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Portal D, Zhou H, Zhao B, Kharchenko PV, Lowry E, Wong L, Quackenbush J, Holloway D, Jiang S, Lu Y, Kieff E. Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18537-42. doi: 10.1073/pnas.1317608110. Epub 2013 Oct 28. PMID: 24167291 PMCID: PMC3832032 read article


Jurado KA, Engelman A. Multimodal mechanism of action of allosteric HIV-1 integrase inhibitors. Expert Rev Mol Med. 2013 Nov 26;15:e14. doi: 10.1017/erm.2013.15. PMID: 24274067 PMCID: PMC3919682 read article


Jurado KA, Wang H, Slaughter A, Feng L, Kessl JJ, Koh Y, Wang W, Ballandras-Colas A, Patel PA, Fuchs JR, Kvaratskhelia M, Engelman A. Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8690-5. doi: 10.1073/pnas.1300703110. Epub 2013 Apr 22. PMID: 23610442 PMCID: PMC3666754 read article


Morin B, Kranzusch PJ, Rahmeh AA, Whelan SP. The polymerase of negative-stranded RNA viruses. Curr Opin Virol. 2013 Apr;3(2):103-10. doi: 10.1016/j.coviro.2013.03.008. Epub 2013 Apr 18. PMID: 23602472 PMCID: PMC4159711 read article


Lee AS, Burdeinick-Kerr R, Whelan SP. A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAs. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):324-9. doi: 10.1073/pnas.1216454109. Epub 2012 Nov 19. PMID: 23169626 PMCID: PMC3538191 read article


Mosammaparast N, Kim H, Laurent B, Zhao Y, Lim HJ, Majid MC, Dango S, Luo Y, Hempel K, Sowa ME, Gygi SP, Steen H, Harper JW, Yankner B, Shi Y. The histone demethylase LSD1/KDM1A promotes the DNA damage response. J Cell Biol. 2013 Nov 11;203(3):457-70. doi: 10.1083/jcb.201302092. PMID: 24217620 PMCID: PMC3824007 read article


Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y. The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Mol Cell Biol. 2013 Nov;33(21):4166-80. doi: 10.1128/MCB.00689-13. Epub 2013 Aug 26. PMID: 23979597 PMCID: PMC3811896 read article


Tan MK, Lim HJ, Bennett EJ, Shi Y, Harper JW. Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. Mol Cell. 2013 Oct 10;52(1):9-24. doi: 10.1016/j.molcel.2013.08.018. Epub 2013 Sep 12. PMID: 24035498 PMCID: PMC3981468 read article


Sciaranghella G, Tong N, Mahan AE, Suscovich TJ, Alter G. Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection. AIDS. 2013 Jan 14;27(2):175-80. doi: 10.1097/QAD.0b013e32835bd1f0. PMID: 23135171 PMCID: PMC3729211 read article


Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies. PLoS Pathog. 2013 Nov;9(11):e1003754. doi: 10.1371/journal.ppat.1003754. Epub 2013 Nov 21. PMID: 24278016 PMCID: PMC3836729 read article


Matreyek KA, Engelman A. Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes. Viruses. 2013 Oct 7;5(10):2483-511. doi: 10.3390/v5102483. PMID: 24103892 PMCID: PMC3814599 read article


Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A. Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration. J Virol. 2013 Jan;87(1):648-58. doi: 10.1128/JVI.01148-12. Epub 2012 Oct 24. PMID: 23097450 PMCID: PMC3536403 read article


Matreyek KA, Yücel SS, Li X, Engelman A. Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity. PLoS Pathog. 2013;9(10):e1003693. doi: 10.1371/journal.ppat.1003693. Epub 2013 Oct 10. PMID: 24130490 PMCID: PMC3795039 read article


McCarthy KR, Schmidt AG, Kirmaier A, Wyand AL, Newman RM, Johnson WE. Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity. PLoS Pathog. 2013 May;9(5):e1003352. doi: 10.1371/journal.ppat.1003352. Epub 2013 May 9. PMID: 23675300 PMCID: PMC3649984 read article


Krupp A, McCarthy KR, Ooms M, Letko M, Morgan JS, Simon V, Johnson WE. APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host. PLoS Pathog. 2013;9(10):e1003641. doi: 10.1371/journal.ppat.1003641. Epub 2013 Oct 3. PMID: 24098115 PMCID: PMC3789815 read article


Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol. 2013 Feb;14(2):179-85. doi: 10.1038/ni.2509. Epub 2012 Dec 23. PMID: 23263557 PMCID: PMC3838897 read article


Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM. Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4492-501. doi: 10.1073/pnas.1316194110. Epub 2013 Nov 6. PMID: 24198334 PMCID: PMC3839728 read article


Shah VB, Shi J, Hout DR, Oztop I, Krishnan L, Ahn J, Shotwell MS, Engelman A, Aiken C. The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating. J Virol. 2013 Jan;87(1):422-32. doi: 10.1128/JVI.07177-11. Epub 2012 Oct 24. PMID: 23097435 PMCID: PMC3536424 read article


Piccinotti S, Kirchhausen T, Whelan SP. Uptake of rabies virus into epithelial cells by clathrin-mediated endocytosis depends upon actin. J Virol. 2013 Nov;87(21):11637-47. doi: 10.1128/JVI.01648-13. Epub 2013 Aug 21. PMID: 23966407 PMCID: PMC3807345 read article


Penaloza-MacMaster P, Provine NM, Ra J, Borducchi EN, McNally A, Simmons NL, Iampietro MJ, Barouch DH. Alternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectors. J Virol. 2013 Feb;87(3):1373-84. doi: 10.1128/JVI.02058-12. Epub 2012 Nov 14. PMID: 23152535 PMCID: PMC3554181 read article


Im EJ, Borducchi EN, Provine NM, McNally AG, Li S, Frankel FR, Barouch DH. An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice. J Virol. 2013 Apr;87(8):4751-5. doi: 10.1128/JVI.03085-12. Epub 2013 Feb 6. PMID: 23388715 PMCID: PMC3624386 read article


Quinlan BD, Gardner MR, Joshi VR, Chiang JJ, Farzan M. Direct expression and validation of phage-selected peptide variants in mammalian cells. J Biol Chem. 2013 Jun 28;288(26):18803-10. doi: 10.1074/jbc.M113.452839. Epub 2013 May 10. PMID: 23667257 PMCID: PMC3696656 read article


Mudhasani R, Tran JP, Retterer C, Radoshitzky SR, Kota KP, Altamura LA, Smith JM, Packard BZ, Kuhn JH, Costantino J, Garrison AR, Schmaljohn CS, Huang IC, Farzan M, Bavari S. IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus. J Virol. 2013 Aug;87(15):8451-64. doi: 10.1128/JVI.03382-12. Epub 2013 May 29. PMID: 23720721 PMCID: PMC3719792  read article


Rahmberg AR, Neidermyer WJ Jr, Breed MW, Alvarez X, Midkiff CC, Piatak M Jr, Lifson JD, Evans DT. Tetherin upregulation in simian immunodeficiency virus-infected macaques. J Virol. 2013 Dec;87(24):13917-21. doi: 10.1128/JVI.01757-13. Epub 2013 Oct 9. PMID: 24109219 PMCID: PMC3838227  read article


Schmidt AG, Xu H, Khan AR, O'Donnell T, Khurana S, King LR, Manischewitz J, Golding H, Suphaphiphat P, Carfi A, Settembre EC, Dormitzer PR, Kepler TB, Zhang R, Moody MA, Haynes BF, Liao HX, Shaw DE, Harrison SC. Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):264-9. doi: 10.1073/pnas.1218256109. Epub 2012 Nov 21. PMID: 23175789 PMCID: PMC3538208  read article


Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, Sette A, Carrington M, Streeck H. Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control. PMID: 23793098 read article


Spangle JM, Münger K. The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species. PLoS Pathog. 2013 Mar;9(3):e1003237. doi: 10.1371/journal.ppat.1003237. Epub 2013 Mar 14. PMID: 23516367 PMCID: PMC3597533 read article


Meyers JM, Spangle JM, Münger K. The human papillomavirus type 8 E6 protein interferes with NOTCH activation during keratinocyte differentiation. J Virol. 2013 Apr;87(8):4762-7. doi: 10.1128/JVI.02527-12. Epub 2013 Jan 30. PMID: 23365452 PMCID: PMC3624394 read article


He J, Sun E, Bujny MV, Kim D, Davidson MW, Zhuang X. Dual Function of CD81 in Influenza Virus Uncoating and Budding. PLoS Pathog. 2013;9(10):e1003701. doi: 10.1371/journal.ppat.1003701. Epub 2013 Oct 10. PMID: 24130495 PMCID:PMC3795033 read article


Sun E, He J, Zhuang X. Dissecting the role of COPI complexes on influenza virus infection. J Virol. 2013 Mar;87(5):2673-85. doi: 10.1128/JVI.02277-12. Epub 2012 Dec 19. PMID: 23255804 PMCID: PMC3571408 read article


Sun E, He J, Zhuang X. Live cell imaging of viral entry. Curr Opin Virol. 2013 Feb;3(1):34-43. doi: 10.1016/j.coviro.2013.01.005. Epub 2013 Feb 7. PMID: 23395264 PMCID: PMC3587724 read article


Vaughan JC, Dempsey GT, Sun E, Zhuang X. Phosphine-quenching of cyanine dyes as a versatile tool for fluorescent microscopy. J Am Chem Soc. 2013 Jan 30;135(4):1197-200. doi: 10.1021/ja3105279. Epub 2013 Jan 17. PMID: 23311875 PMCID: PMC3624894 read article


Tan MK, Lim HJ, Bennett EJ, Shi Y, Harper JW. Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. Mol Cell. 2013 Oct 10;52(1):9-24. doi: 10.1016/j.molcel.2013.08.018. Epub 2013 Sep 12. PMID: 24035498 PMCID: PMC3981468 read article


Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y. The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Mol Cell Biol. 2013 Nov;33(21):4166-80. doi: 10.1128/MCB.00689-13. Epub 2013 Aug 26. PMID: 23979597 PMCID: PMC3811896 read article


Munger K, Gwin TK, McLaughlin-Drubin ME. p16 in HPV-associated cancers. Oncotarget. 2013 Nov;4(11):1864-5. PMID:24192550 PMCID: PMC3875753 read article


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2012


Mukerji J, Olivieri KC, Misra V, Agopian KA, Gabuzda D. Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation. Retrovirology. 2012 Jun 22;9:33. doi: 10.1186/1742-4690-9-33. PMID: 22534017 PMCID: PMC3382630 read article


Alpert MD, Harvey JD, Lauer WA, Reeves RK, Piatak M Jr, Carville A, Mansfield KG, Lifson JD, Li W, Desrosiers RC, Johnson RP, Evans DT. ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge. PLoS Pathog. 2012;8(8):e1002890. doi: 10.1371/journal.ppat.1002890. Epub 2012 Aug 23. PMID: 22927823 PMCID: PMC3426556 read article


Alpert MD, Heyer LN, Williams DE, Harvey JD, Greenough T, Allhorn M, Evans DT. A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays. J Virol. 2012 Nov;86(22):12039-52. doi: 10.1128/JVI.01650-12. Epub 2012 Aug 29. PMID: 22933282 PMCID: PMC3486484  read article


Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL, Adelmant G, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J, Marto JA, Hill DE, Cusick ME, Vidal M, Florens L, Washburn MP, Litovchick L, DeCaprio JA. Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog. 2012;8(10):e1002949. doi: 10.1371/journal.ppat.1002949. Epub 2012 Oct 18. PMID:23093934 PMCID:PMC3475652 read article


Cureton DK, Burdeinick-Kerr R, Whelan SP. Genetic inactivation of COPI coatomer separately inhibits vesicular stomatitis virus entry and gene expression. J Virol. 2012 Jan;86(2):655-66. doi: 10.1128/JVI.05810-11. Epub 2011 Nov 9. PMID: 22072764 PMCID: PMC3255828  read article


Chiang JJ, Gardner MR, Quinlan BD, Dorfman T, Choe H, Farzan M. Enhanced recognition and neutralization of HIV-1 by antibody-derived CCR5-mimetic peptide variants. J Virol. 2012 Nov;86(22):12417-21. doi: 10.1128/JVI.00967-12. Epub 2012 Aug 29. PMID: 22933279 PMCID: PMC3486504 read article


Bailey CC, Huang IC, Kam C, Farzan M. Ifitm3 limits the severity of acute influenza in mice. PLoS Pathog. 2012 Sep;8(9):e1002909. doi: 10.1371/journal.ppat.1002909. Epub 2012 Sep 6. PMID: 22969429 PMCID: PMC3435252 read article


Chan YK, Huang IC, Farzan M. IFITM proteins restrict antibody-dependent enhancement of dengue virus infection. PLoS One. 2012;7(3):e34508. doi: 10.1371/journal.pone.0034508. Epub 2012 Mar 30. PMID: 22479637 PMCID:PMC3316688 read article


Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, Kvaratskhelia M, Hughes SH, Engelman A. HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Res. 2012 Dec;40(22):11518-30. doi: 10.1093/nar/gks913. Epub 2012 Oct 5. PMID: 23042676 PMCID: PMC3526291 read article


Kranzusch PJ, Whelan SP. Architecture and regulation of negative-strand viral enzymatic machinery. RNA Biol. 2012 Jul;9(7):941-8. doi: 10.4161/rna.20345. Epub 2012 Jul 1. PMID: 22767259 PMCID: PMC3495737  read article


Matreyek KA, Oztop I, Freed EO, Engelman A. Viral latency and potential eradication of HIV-1. Expert Rev Anti Infect Ther. 2012 Aug;10(8):855-7. doi: 10.1586/eri.12.68. PMID: 23030323 PMCID: PMC3573755 read article


Mukerji J, Olivieri KC, Misra V, Agopian KA, Gabuzda D. Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation. Retrovirology. 2012 Jun 22;9:33. doi: 10.1186/1742-4690-9-33. PMID: 22534017 PMCID: PMC3382630 read article


Orzalli MH, DeLuca NA, Knipe DM. Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):E3008-17. doi: 10.1073/pnas.1211302109. Epub 2012 Oct 1.PMID: 23027953 PMCID: PMC3497734 read article


Martínez-Noël G, Galligan JT, Sowa ME, Arndt V, Overton TM, Harper JW, Howley PM. Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Mol Cell Biol. 2012 Aug;32(15):3095-106. doi: 10.1128/MCB.00201-12. Epub 2012 May 29. PMID: 22645313 PMCID: PMC3434508 read article


Matreyek KA, Oztop I, Freed EO, Engelman A. Viral latency and potential eradication of HIV-1. Expert Rev Anti Infect Ther. 2012 Aug;10(8):855-7. doi: 10.1586/eri.12.68. PMID: 23030323 PMCID: PMC3573755 read article


Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN. Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection. J Virol. 2012 Apr;86(8):4708-14. doi: 10.1128/JVI.05887-11. Epub 2012 Feb 1. PMID: 22301145 PMCID: PMC3318671 read article


Soghoian DZ, Jessen H, Flanders M, Sierra-Davidson K, Cutler S, Pertel T, Ranasinghe S, Lindqvist M, Davis I, Lane K, Rychert J, Rosenberg ES, Piechocka-Trocha A, Brass AL, Brenchley JM, Walker BD, Streeck H. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci Transl Med. 2012 Feb 29;4(123):123ra25. doi: 10.1126/scitranslmed.3003165. PMID: 22378925 PMCID: PMC3918726 read article


Lindqvist M, van Lunzen J, Soghoian DZ, Kuhl BD, Ranasinghe S, Kranias G, Flanders MD, Cutler S, Yudanin N, Muller MI, Davis I, Farber D, Hartjen P, Haag F, Alter G, Schulze zur Wiesch J, Streeck H. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest. 2012 Sep 4;122(9):3271-80. doi: 10.1172/JCI64314. Epub 2012 Aug 27. PMID: 22922259 PMCID: PMC3428098 read article


Ranasinghe S, Flanders M, Cutler S, Soghoian DZ, Ghebremichael M, Davis I, Lindqvist M, Pereyra F, Walker BD, Heckerman D, Streeck H. HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome. J Virol. 2012 Jan;86(1):277-83. doi: 10.1128/JVI.05577-11. Epub 2011 Oct 26. PMID: 22031937 PMCID: PMC3255877 read article


Spangle JM, Ghosh-Choudhury N, Münger K. Activation of cap-dependent translation by mucosal human papillomavirus E6 proteins is dependent on the integrity of the LXXLL binding motif. J Virol. 2012 Jul;86(14):7466-72. doi: 10.1128/JVI.00487-12. Epub 2012 May 2. PMID: 22553330 PMCID: PMC3416298 read article


Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature. 2012 Jul 26;487(7408):491-5. doi: 10.1038/nature11288. PMID: 22810586 PMCID: PMC3408847 read article


Harper JW, Tan MK. Understanding cullin-RING E3 biology through proteomics-based substrate identification. Mol Cell Proteomics. 2012 Dec;11(12):1541-50. doi: 10.1074/mcp.R112.021154. Epub 2012 Sep 7. PMID: 22962057 PMCID: PMC3518111 read article


White EA, Kramer RE, Tan MJ, Hayes SD, Harper JW, Howley PM. Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity. J Virol. 2012 Dec;86(24):13174-86. doi: 10.1128/JVI.02172-12. Epub 2012 Sep 26. PMID: 23015706 PMCID: PMC3503137 read article


White EA, Sowa ME, Tan MJ, Jeudy S, Hayes SD, Santha S, Münger K, Harper JW, Howley PM. Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):E260-7. doi: 10.1073/pnas.1116776109. Epub 2012 Jan 9. PMID: 22232672 PMCID: PMC3277141 read article


Tan MJ, White EA, Sowa ME, Harper JW, Aster JC, Howley PM. Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):E1473-80. doi: 10.1073/pnas.1205991109. Epub 2012 Apr 30. PMID: 22547818 PMCID: PMC3384212 read article


Li H, Rhee EG, Masek-Hammerman K, Teigler JE, Abbink P, Barouch DH. Adenovirus serotype 26 utilizes CD46 as a primary cellular receptor and only transiently activates T lymphocytes following vaccination of rhesus monkeys. J Virol. 2012 Oct;86(19):10862-5. doi: 10.1128/JVI.00928-12. Epub 2012 Jul 18. PMID: 22811531 PMCID: PMC3457266 read article


Teigler JE, Iampietro MJ, Barouch DH. Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeys. J Virol. 2012 Sep;86(18):9590-8. doi: 10.1128/JVI.00740-12. Epub 2012 Jul 11. PMID: 22787208 PMCID: PMC3446581  read article


Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL, Adelmant G, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J, Marto JA, Hill DE, Cusick ME, Vidal M, Florens L, Washburn MP, Litovchick L, DeCaprio JA. Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog. 2012;8(10):e1002949. doi: 10.1371/journal.ppat.1002949. Epub 2012 Oct 18. PMID: 23093934 PMCID: PMC3475652 read article


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2011


Moldt B, Schultz N, Dunlop DC, Alpert MD, Harvey JD, Evans DT, Poignard P, Hessell AJ, Burton DR. A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV. J Virol. 2011 Oct;85(20):10572-81. Epub 2011 Aug 17. PMID: 21849450 PMCID: PMC3187489 read article


Aoki ST, Trask SD, Coulson BS, Greenberg HB, Dormitzer PR, Harrison SC. Cross-linking of rotavirus outer capsid protein VP7 by antibodies or disulfides inhibits viral entry. J Virol. 2011 Oct;85(20):10509-17. Epub 2011 Aug 17. PMID: 21849465 PMCID: PMC3187514 read article


Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. Nature. 2011 Aug 24;477(7364):344-8. doi: 10.1038/nature10380. PMID: 21866101 PMCID: PMC3230319 read article


Stanifer ML, Cureton DK, Whelan SP. A recombinant vesicular stomatitis virus bearing a lethal mutation in the glycoprotein gene uncovers a second site suppressor that restores fusion. J Virol. 2011 Aug;85(16):8105-15. doi: 10.1128/JVI.00735-11. Epub 2011 Jun 15. PMID: 21680501 PMCID: PMC3147994  read article


Kasprowicz VO, Mitchell JE, Chetty S, Govender P, Huang KH, Fletcher HA, Webster DP, Brown S, Kasmar A, Millington K, Day CL, Mkhwanazi N, McClurg C, Chonco F, Lalvani A, Walker BD, Ndung'u T, Klenerman P. A molecular assay for sensitive detection of pathogen-specific T-cells. PLoS One. 2011;6(8):e20606. doi: 10.1371/journal.pone.0020606. Epub 2011 Aug 11. PMID: 21853018 PMCID: PMC3154901 read article


De León Vázquez E, Kaye KM. The internal Kaposi's sarcoma-associated herpesvirus LANA regions exert a critical role on episome persistence. J Virol. 2011 Aug;85(15):7622-33. doi: 10.1128/JVI.00304-11. Epub 2011 May 18. PMID: 21593163 PMCID: PMC3147901  read article


De León Vázquez E, Kaye KM. Rapid and quantitative assessment of KSHV LANA-mediated DNA replication. Arch Virol. 2011 Aug;156(8):1323-33. doi: 10.1007/s00705-011-0985-0. Epub 2011 Apr 7. PMID: 21472413 PMCID: PMC3145832 read article


Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF,Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U, Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell. 2011 Nov 11;147(4):853-67. doi: 10.1016/j.cell.2011.10.022. PMID: 22078882 PMCID: PMC3809888 read article


Li X, Yeung DF, Fiegen AM, Sodroski J. Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins. J Biol Chem. 2011 Aug 12;286(32):27959-70. Epub 2011 Jun 16. PMID: 21680743 PMCID: PMC3151041 read article


Gomila RC, Martin GW, Gehrke L. NF90 binds the dengue virus RNA 3' terminus and is a positive regulator of dengue virus replication. PLoS One. 2011 Feb 28;6(2):e16687. doi: 10.1371/journal.pone.0016687. PMID: 21386893 PMCID: PMC3046124 read article


Huang IC, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, Longobardi LE, Boltz D, Kuhn JH, Elledge SJ, Bavari S, Denison MR, Choe H, Farzan M. Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011 Jan 6;7(1):e1001258. doi: 10.1371/journal.ppat.1001258. PMID: 21253575 PMCID: PMC3017121 read article


Ivanovic T, Boulant S, Ehrlich M, Demidenko AA, Arnold MM, Kirchhausen T, Nibert ML. Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking. Traffic. 2011 Sep;12(9):1179-95. doi: 10.1111/j.1600-0854.2011.01233.x. Epub 2011 Jul 7. PMID: 21736684 PMCID: PMC3575638 read article


Kingston D, Chang H, Ensser A, Lee HR, Lee J, Lee SH, Jung JU, Cho NH. Inhibition of retromer activity by herpesvirus saimiri tip leads to CD4 downregulation and efficient T cell transformation. J Virol. 2011 Oct;85(20):10627-38. Epub 2011 Aug 17. PMID: 21849449 PMCID: PMC3187508 read article


Kranzusch PJ, Whelan SP. Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19743-8. Epub 2011 Nov 21. PMID: 22106304 PMCID: PMC3241799 read article


Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature. 2011 Aug 24;477(7364):340-3. doi: 10.1038/nature10348. PMID: 21866103 PMCID: PMC3175325 read article


Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH. Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. J Virol. 2011 Sep;85(17):8502-13. Epub 2011 Jun 22. PMID: 21697477 PMCID: PMC3165852 read article


Mostafa HH1, Thompson TW, Kushnir AS, Haenchen SD, Bayless AM, Hilliard JG, Link MA, Pitcher LA, Loveday E, Schaffer PA, Davido DJ. Herpes simplex virus 1 ICP0 phosphorylation site mutants are attenuated for viral replication and impaired for explant-induced reactivation. J Virol. 2011 Dec;85(23):12631-7. doi: 10.1128/JVI.05661-11. Epub 2011 Sep 21. PMID: 21937654 PMCID: PMC3209388  read article


Tan MK, Lim HJ, Harper JW. SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. Mol Cell Biol. 2011 Sep;31(18):3687-99. doi: 10.1128/MCB.05746-11. Epub 2011 Jul 18. PMID: 21768309 PMCID: PMC3165736  read article


Mostafa HH, Thompson TW, Kushnir AS, Haenchen SD, Bayless AM, Hilliard JG, Link MA, Pitcher LA, Loveday E, Schaffer PA, Davido DJ. Herpes simplex virus 1 ICP0 phosphorylation site mutants are attenuated for viral replication and impaired for explant-induced reactivation. J Virol. 2011 Dec;85(23):12631-7. doi: 10.1128/JVI.05661-11. Epub 2011 Sep 21. PMID: 21937654 PMCID: PMC3209388  read article


Koh Y, Matreyek KA, Engelman A. Differential sensitivities of retroviruses to integrase strand transfer inhibitors. J Virol. 2011 Apr;85(7):3677-82. doi: 10.1128/JVI.02541-10. Epub 2011 Jan 26. PMID: 21270168 PMCID: PMC3067883 read article


Matreyek KA, Engelman A. The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid. J Virol. 2011 Aug;85(15):7818-27. doi: 10.1128/JVI.00325-11. Epub 2011 May 18. PMID: 21593146 PMCID: PMC3147902 read article


Olivieri KC, Mukerji J, Gabuzda D. Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2. Retrovirology. 2011 Aug 5;8:64. doi: 10.1186/1742-4690-8-64. PMID: 21819585 PMCID: PMC3169461 read article


Colantonio AD, Bimber BN, Neidermyer WJ Jr, Reeves RK, Alter G, Altfeld M, Johnson RP, Carrington M, O'Connor DH, Evans DT. KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif. PLoS Pathog. 2011 Mar;7(3):e1001316. doi: 10.1371/journal.ppat.1001316. Epub 2011 Mar 10. PMID: 21423672 PMCID: PMC3053351 read article


Chiang JJ, Gardner MR, Quinlan BD, Dorfman T, Choe H, Farzan M. A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein. J Virol. 2011 Aug;85(15):7563-71. doi: 10.1128/JVI.00630-11. Epub 2011 May 25. PMID: 21613393 PMCID: PMC3147930 read article


Choe H, Jemielity S, Abraham J, Radoshitzky SR, Farzan M. Transferrin receptor 1 in the zoonosis and pathogenesis of New World hemorrhagic fever arenaviruses. Curr Opin Microbiol. 2011 Aug;14(4):476-82. doi: 10.1016/j.mib.2011.07.014. Epub 2011 Jul 30. PMID: 21807555 PMCID: PMC3159852 read article


Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH. Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. J Virol. 2011 Sep;85(17):8502-13. doi: 10.1128/JVI.02600-10. Epub 2011 Jun 22. PMID: 21697477 PMCID: PMC3165852  read article


Huang IC, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, Longobardi LE, Boltz D, Kuhn JH, Elledge SJ, Bavari S, Denison MR, Choe H, Farzan M. Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011 Jan 6;7(1):e1001258. doi: 10.1371/journal.ppat.1001258. PMID: 21253575 PMCID: PMC3017121  read article


Rahman S, Sowa ME, Ottinger M, Smith JA, Shi Y, Harper JW, Howley PM. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3. Mol Cell Biol. 2011 Jul;31(13):2641-52. doi: 10.1128/MCB.01341-10. Epub 2011 May 9. PMID: 21555454 PMCID: PMC3133372 read article


Silva LA, Strang BL, Lin EW, Kamil JP, Coen DM. Sites and roles of phosphorylation of the human cytomegalovirus DNA polymerase subunit UL44. Virology. 2011 Sep 1;417(2):268-80. doi: 10.1016/j.virol.2011.06.008. Epub 2011 Jul 23. PMID: 21784501 PMCID: PMC3434964  read article


Chevalier MF, Jülg B, Pyo A, Flanders M, Ranasinghe S, Soghoian DZ, Kwon DS, Rychert J, Lian J, Muller MI, Cutler S, McAndrew E, Jessen H, Pereyra F, Rosenberg ES, Altfeld M, Walker BD, Streeck H. HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function. J Virol. 2011 Jan;85(2):733-41. doi: 10.1128/JVI.02030-10. Epub 2010 Nov 3. PMID: 21047960 PMCID: PMC3020027 read article


Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W. mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030. PMID: 22017875 PMCID: PMC3229299 read article


Tan MK, Lim HJ, Harper JW. SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. Mol Cell Biol. 2011 Sep;31(18):3687-99. doi: 10.1128/MCB.05746-11. Epub 2011 Jul 18. PMID: 21768309 PMCID: PMC3165736 read article


Aoki ST, Trask SD, Coulson BS, Greenberg HB, Dormitzer PR, Harrison SC. Cross-linking of rotavirus outer capsid protein VP7 by antibodies or disulfides inhibits viral entry. J Virol. 2011 Oct;85(20):10509-17. doi: 10.1128/JVI.00234-11. Epub 2011 Aug 17. PMID: 21849465 PMCID: PMC3187514  read article


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2010


Olivieri KC1, Agopian KA, Mukerji J, Gabuzda D. Evidence for adaptive evolution at the divergence between lymphoid and brain HIV-1 nef genes. AIDS Res Hum Retroviruses. 2010 Apr;26(4):495-500. doi: 10.1089/aid.2009.0257. PMID: 20377428 PMCID: PMC2933169  read article


Alpert MD, Rahmberg AR, Neidermyer W, Ng SK, Carville A, Camp JV, Wilson RL, Piatak M Jr, Mansfield KG, Li W, Miller CJ, Lifson JD, Kozlowski PA, Evans DT. Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challenge. J Virol. 2010 Oct;84(20):10748-64. Epub 2010 Aug 11. PMID: 20702641 PMCID: PMC2950576 read article


Miller CL, Arnold MM, Broering TJ, Hastings CE, Nibert ML. Localization of mammalian orthoreovirus proteins to cytoplasmic factory-like structures via nonoverlapping regions of microNS. J Virol. 2010 Jan;84(2):867-82. Epub 2009 Nov 4. PMID: 19889754 PMCID: PMC2798337 read article


Rowley CF, Boutwell CL, Lee EJ, MacLeod IJ, Ribaudo HJ, Essex M, Lockman S. Ultrasensitive detection of minor drug-resistant variants for HIV after nevirapine exposure using allele-specific PCR: clinical significance. AIDS Res Hum Retroviruses. 2010 Mar;26(3):293-300. doi: 10.1089/aid.2009.0082. PMID: 20334564 PMCID: PMC2864062 read article


Cureton DK, Massol RH, Whelan SP, Kirchhausen T. The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis. PLoS Pathog. 2010 Sep 30;6(9):e1001127. doi: 10.1371/journal.ppat.1001127. PMID: 20941355 PMCID: PMC2947997  read article


Heinrich BS, Cureton DK, Rahmeh AA, Whelan SP. Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions. PLoS Pathog. 2010 Jun 24;6(6):e1000958. doi: 10.1371/journal.ppat.1000958. PMID: 20585632 PMCID: PMC2891829  read article


Tan CS, Ellis LC, Wüthrich C, Ngo L, Broge TA Jr, Saint-Aubyn J, Miller JS, Koralnik IJ. JC virus latency in the brain and extraneural organs of patients with and without progressive multifocal leukoencephalopathy. J Virol. 2010 Sep;84(18):9200-9. Epub 2010 Jul 7. PubMed PMID: 20610709; PubMed Central PMCID: PMC2937633. read article


Johnson KE, Knipe DM. Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation. Virology. 2010 Jan 5;396(1):21-9. Epub 2009 Oct 31. PMID: 19879619 PMCID: PMC2787861 read article


Kim IS, Trask SD, Babyonyshev M, Dormitzer PR, Harrison SC. Effect of mutations in VP5 hydrophobic loops on rotavirus cell entry. J Virol. 2010 Jun;84(12):6200-7. Epub 2010 Apr 7. PMID: 20375171 PMCID: PMC2876642 read article


Rahmeh AA, Schenk AD, Danek EI, Kranzusch PJ, Liang B, Walz T, Whelan SP. Molecular architecture of the vesicular stomatitis virus RNA polymerase. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20075-80. Epub 2010 Nov 1. PMID: 21041632 PMCID: PMC2993402 read article


Kranzusch PJ, Schenk AD, Rahmeh AA, Radoshitzky SR, Bavari S, Walz T, Whelan SP. Assembly of a functional Machupo virus polymerase complex. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20069-74. Epub 2010 Oct 26. PMID: 20978208 PMCID: PMC2993349 read article


Liu W, Li Y, Learn GH, Rudicell RS, Robertson JD, Keele BF, Ndjango JB, Sanz CM, Morgan DB, Locatelli S, Gonder MK, Kranzusch PJ, Walsh PD, Delaporte E, Mpoudi-Ngole E, Georgiev AV, Muller MN, Shaw GM, Peeters M, Sharp PM, Rayner JC, Hahn BH. Origin of the human malaria parasite Plasmodium falciparum in gorillas. Nature. 2010 Sep 23;467(7314):420-5. PMID: 20864995 PMCID: PMC2997044 read article


Radoshitzky SR, Dong L, Chi X, Clester JC, Retterer C, Spurgers K, Kuhn JH, Sandwick S, Ruthel G, Kota K, Boltz D, Warren T, Kranzusch PJ, Whelan SP, Bavari S. Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin. J Virol. 2010 Oct;84(20):10569-80. Epub 2010 Aug 4. PMID: 20686043 PMCID: PMC2950602 read article


Neel C, Etienne L, Li Y, Takehisa J, Rudicell RS, Bass IN, Moudindo J, Mebenga A, Esteban A, Van Heuverswyn F, Liegeois F, Kranzusch PJ, Walsh PD, Sanz CM, Morgan DB, Ndjango JB, Plantier JC, Locatelli S, Gonder MK, Leendertz FH, Boesch C, Todd A, Delaporte E, Mpoudi-Ngole E, Hahn BH, Peeters M. Molecular epidemiology of simian immunodeficiency virus infection in wild-living gorillas. J Virol. 2010 Feb;84(3):1464-76. Epub 2009 Nov 11. PMID: 19906908 PMCID: PMC2812320 read article


Kushnir AS, Davido DJ, Schaffer PA. Role of nuclear factor Y in stress-induced activation of the herpes simplex virus type 1 ICP0 promoter. J Virol. 2010 Jan;84(1):188-200. doi: 10.1128/JVI.01377-09. PMID: 19828605 PMCID: PMC2798407  read article


Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC. Peroxisomes are signaling platforms for antiviral innate immunity. Cell. 2010 May 14;141(4):668-81. doi: 10.1016/j.cell.2010.04.018. Epub 2010 May 6. PMID: 20451243 PMCID: PMC3670185 read article


Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 2010 Jul 22;466(7305):503-7. doi: 10.1038/nature09261. Epub 2010 Jul 11. PMID: 20622853 PMCID: PMC3072215 read article


Manuel ER, Yeh WW, Balachandran H, Clarke RH, Lifton MA, Letvin NL. Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral control. J Virol. 2010 Dec;84(24):12782-9. Epub 2010 Sep 29. PMID: 20881040 PMCID: PMC3004339 read article


Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A. The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase. J Virol. 2010 Jan;84(1):397-406. doi: 10.1128/JVI.01899-09. Epub 2009 Oct 21. PMID: 19846519 PMCID: PMC2798409 read article


Holman AG, Mefford ME, O'Connor N, Gabuzda D. HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites. AIDS Res Ther. 2010 Dec 14;7:43. PMID: 21156070 PMCID: PMC3018377 read article


Moldovan GL, Madhavan MV, Mirchandani KD, McCaffrey RM, Vinciguerra P, D'Andrea AD. DNA polymerase POLN participates in cross-link repair and homologous recombination. Mol Cell Biol. 2010 Feb;30(4):1088-96. doi: 10.1128/MCB.01124-09. Epub 2009 Dec 7. PMID: 19995904 PMCID: PMC2815579  read article


Olivieri KC, Agopian KA, Mukerji J, Gabuzda D. Evidence for adaptive evolution at the divergence between lymphoid and brain HIV-1 nef genes. AIDS Res Hum Retroviruses. 2010 Apr;26(4):495-500. doi: 10.1089/aid.2009.0257. PMID: 20377428 PMCID: PMC2933169 read article


Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman DR, Coffin JM, Hughes SH, Unutmaz D, Engelman A, KewalRamani VN. Flexible use of nuclear import pathways by HIV-1. Cell Host Microbe. 2010 Mar 18;7(3):221-33. doi: 10.1016/j.chom.2010.02.007. PMID: 20227665 PMCID: PMC2841689 read article


Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A. The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase. J Virol. 2010 Jan;84(1):397-406. doi: 10.1128/JVI.01899-09. Epub 2009 Oct 21. PMID: 19846519 PMCID: PMC2798409 read article


Rogers TF, Lim SY, Sundsvold TJ, Chan T, Hsu A, Letvin NL. Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death. Virol J. 2010 Apr 26;7:79. PMID: 20416115 PMCID: PMC2874537 read article


Lim SY, Rogers T, Chan T, Whitney JB, Kim J, Sodroski J, Letvin NL. TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys. PLoS Pathog. 2010 Jan 22;6(1):e1000738. PMID: 20107597 PMCID: PMC2809762 read article


Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of flavivirus entry derived from the E protein stem. J Virol. 2010 Dec;84(24):12549-54. Epub 2010 Sep 29. PMID: 20881042 PMCID: PMC3004314 read article


Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late-stage fusion intermediate. PLoS Pathog. 2010 Apr 8;6(4):e1000851. PMID: 20386713 PMCID: PMC2851732 read article


Silva LA, Loregian A, Pari GS, Strang BL, Coen DM. The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication. J Virol. 2010 Nov;84(21):11563-8. doi: 10.1128/JVI.01033-10. Epub 2010 Aug 25. PMID: 20739543 PMCID: PMC2953201  read article


Soghoian DZ, Streeck H. Cytolytic CD4(+) T cells in viral immunity. Expert Rev Vaccines. 2010 Dec;9(12):1453-63. doi: 10.1586/erv.10.132. PMID: 21105780 PMCID: PMC3033049 read article


Spangle JM, Münger K. The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. J Virol. 2010 Sep;84(18):9398-407. doi: 10.1128/JVI.00974-10. Epub 2010 Jul 14. PMID: 20631133 PMCID: PMC2937655  read article


Shao RX, Zhang L, Peng LF, Sun E, Chung WJ, Jang JY, Tsai WL, Hyppolite G, Chung RT. Suppressor of cytokine signaling 3 suppresses Hepatitis C Virus replication in an mTOR-dependent manner. J Virol. 2010 Jun;84(12):6060-9. doi: 10.1128/JVI.02484-09. Epub 2010 Apr 7. PMID: 20375166 PMCID: PMC2876663 read article


Kim IS, Trask SD, Babyonyshev M, Dormitzer PR, Harrison SC. Effect of mutations in VP5 hydrophobic loops on rotavirus cell entry. J Virol. 2010 Jun;84(12):6200-7. doi: 10.1128/JVI.02461-09. Epub 2010 Apr 7. PMID: 20375171 PMCID: PMC2876642  read article


Trask SD, Kim IS, Harrison SC, Dormitzer PR. A rotavirus spike protein conformational intermediate binds lipid bilayers. J Virol. 2010 Feb;84(4):1764-70. doi: 10.1128/JVI.01682-09. Epub 2009 Dec 9. PMID: 20007281 PMCID: PMC2812363  read article


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2009


Aoki ST, Settembre EC, Trask SD, Greenberg HB, Harrison SC, Dormitzer PR. Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science. 2009 Jun 12;324(5933):1444-7. PMID: 19520960 PMCID: PMC2995306 read article


Chen JZ, Settembre EC, Aoki ST, Zhang X, Bellamy AR, Dormitzer PR, Harrison SC, Grigorieff N. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10644-8. Epub 2009 Jun 1. PMID: 19487668 PMCID: PMC2689313 read article


Boutwell CL, Rowley CF, Essex M. Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein. J Virol. 2009 Mar;83(6):2460-8. doi: 10.1128/JVI.01970-08. Epub 2008 Dec 24. PMID: 19109381 PMCID: PMC2648284 read article


Bowman JJ, Schaffer PA. Origin of expression of the herpes simplex virus type 1 protein U(S)1.5. J Virol. 2009 Sep;83(18):9183-94. Epub 2009 Jul 1. PMID: 19570862 PMCID: PMC2738232 read article


Bowman JJ, Orlando JS, Davido DJ, Kushnir AS, Schaffer PA. Transient expression of herpes simplex virus type 1 ICP22 represses viral promoter activity and complements the replication of an ICP22 null virus. J Virol. 2009 Sep;83(17):8733-43. Epub 2009 Jun 17. PMID: 19535441 PMCID: PMC2738139 read article


Mackay LK, Long HM, Brooks JM, Taylor GS, Leung CS, Chen A, Wang F, Rickinson AB. T cell detection of a B-cell tropic virus infection: newly-synthesised versus mature viral proteins as antigen sources for CD4 and CD8 epitope display. PLoS Pathog. 2009 Dec;5(12):e1000699. doi: 10.1371/journal.ppat.1000699. Epub 2009 Dec 18. PMID: 20019813 PMCID: PMC2788701  read article


Cureton DK, Massol RH, Saffarian S, Kirchhausen TL, Whelan SP. Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization. PLoS Pathog. 2009 Apr;5(4):e1000394. doi: 10.1371/journal.ppat.1000394. Epub 2009 Apr 24. PMID: 19390604 PMCID: PMC2667253  read article


Ramduth D, Day CL, Thobakgale CF, Mkhwanazi NP, de Pierres C, Reddy S, van der Stok M, Mncube Z, Nair K, Moodley ES, Kaufmann DE, Streeck H, Coovadia HM, Kiepiela P, Goulder PJ, Walker BD. Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection. PLoS One. 2009;4(4):e5013. doi: 10.1371/journal.pone.0005013. Epub 2009 Apr 7. PMID: 19352428 PMCID: PMC2661367  read article


Kelley-Clarke B, De León Vázquez E, Slain K, Barbera AJ, Kaye KM. Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence. J Virol. 2009 May;83(9):4326-37. doi: 10.1128/JVI.02395-08. Epub 2009 Feb 18. PMID: 19225000 PMCID: PMC2668501 read article


Dunfee RL, Thomas ER, Gabuzda D. Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12. Retrovirology. 2009 Jul 20;6:69. doi: 10.1186/1742-4690-6-69. PMID: 19619305 PMCID: PMC2717910 read article


Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d. J Biol Chem. 2009 Dec 4;284(49):33800-6. Epub 2009 Oct 15. PMID: 19833737 PMCID: PMC2797149 read article


Brass AL1, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ. The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell. 2009 Dec 24;139(7):1243-54. doi: 10.1016/j.cell.2009.12.017. PMID: 20064371 PMCID: PMC2824905 read article


Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe. 2009 May 8;5(5):439-49. doi: 10.1016/j.chom.2009.04.006. PMID: 19454348 PMCID: PMC2737813 read article


Rozenblatt-Rosen O1, Nagaike T, Francis JM, Kaneko S, Glatt KA, Hughes CM, LaFramboise T, Manley JL, Meyerson M. The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):755-60. doi: 10.1073/pnas.0812023106. Epub 2009 Jan 9. PMID: 19136632 PMCID: PMC2615665 read article


Zhang L, Agosto MA, Ivanovic T, King DS, Nibert ML, Harrison SC. Requirements for the formation of membrane pores by the reovirus myristoylated micro1N peptide. J Virol. 2009 Jul;83(14):7004-14. doi: 10.1128/JVI.00377-09. Epub 2009 May 13. PMID:
19439475 PMCID: PMC2704788
 read article


Gredmark-Russ S, Isaacson MK, Kattenhorn L, Cheung EJ, Watson N, Ploegh HL. A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection. J Virol. 2009 Oct;83(20):10644-52. doi: 10.1128/JVI.01017-09. Epub 2009 Aug 12. PMID: 19706716 PMCID: PMC2753118  read article


Kelley-Clarke B, De Leon-Vazquez E, Slain K, Barbera AJ, Kaye KM. Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence. J Virol. 2009 May;83(9):4326-37. doi: 10.1128/JVI.02395-08. Epub 2009 Feb 18. PMID: 19225000 PMCID: PMC2668501 read article


Trask SD, Kim IS, Harrison SC, Dormitzer PR. A rotavirus spike protein conformational intermediate binds lipid bilayers. J Virol. 2010 Feb;84(4):1764-70. Epub 2009 Dec 9. PMID: 20007281 PMCID: PMC2812363 read article


Rahmeh AA, Li J, Kranzusch PJ, Whelan SP. Ribose 2'-O methylation of the vesicular stomatitis virus mRNA cap precedes and facilitates subsequent guanine-N-7 methylation by the large polymerase protein. J Virol. 2009 Nov;83(21):11043-50. Epub 2009 Aug 26. PMID: 19710136 PMCID: PMC2772757.  read article


Bowman JJ, Orlando JS, Davido DJ, Kushnir AS, Schaffer PA. Transient expression of herpes simplex virus type 1 ICP22 represses viral promoter activity and complements the replication of an ICP22 null virus. J Virol. 2009 Sep;83(17):8733-43. doi: 10.1128/JVI.00810-09. Epub 2009 Jun 17. PMID: 19535441 PMCID: PMC2738139  read article


Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, Chowdhury D, Dykxhoorn DM, Tsai P, Hofmann O, Becker KG, Gorospe M, Hide W, Lieberman J. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell. 2009 Sep 11;35(5):610-25. doi: 10.1016/j.molcel.2009.08.020. PMID: 19748357 PMCID: PMC2757794  read article


Manuel ER, Yeh WW, Seaman MS, Furr K, Lifton MA, Hulot SL, Autissier P, Letvin NL. Dominant CD8+ T-lymphocyte responses suppress expansion of vaccine-elicited subdominant T lymphocytes in rhesus monkeys challenged with pathogenic simian-human immunodeficiency virus. J Virol. 2009 Oct;83(19):10028-35. Epub 2009 Jul 29. PMID: 19641002 PMCID: PMC2748023 read article


Hulot SL, Seaman MS, Sen P, Autissier PA, Manuel ER, Letvin NL. Diverse cross-reactive potential and Vbeta gene usage of an epitope-specific cytotoxic T-lymphocyte population in monkeys immunized with diverse human immunodeficiency virus type 1 Env immunogens. J Virol. 2009 Oct;83(19):9803-12. Epub 2009 Jul 29. PMID: 19640988 PMCID: PMC2748000 read article


Haim H, Si Z, Madani N, Wang L, Courter JR, Princiotto A, Kassa A, DeGrace M, McGee-Estrada K, Mefford M, Gabuzda D, Smith AB 3rd, Sodroski J. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathog. 2009 Apr;5(4):e1000360. Epub 2009 Apr 3. PMID: 19343205 PMCID: PMC2655723 read article


Alam SM, Morelli M, Dennison SM, Liao HX, Zhang R, Xia SM, Rits-Volloch S, Sun L, Harrison SC, Haynes BF, Chen B. Role of HIV membrane in neutralization by two broadly neutralizing antibodies. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20234-9. doi: 10.1073/pnas.0908713106. Epub 2009 Nov 11. PMID: 19906992 PMCID: PMC2787149 read article


Engelman A, Oztop I, Vandegraaff N, Raghavendra NK. Quantitative analysis of HIV-1 preintegration complexes. Methods. 2009 Apr;47(4):283-90. doi: 10.1016/j.ymeth.2009.02.005. Epub 2009 Feb 20. PMID: 19233280 PMCID: PMC2673482 read article


Abraham J, Kwong JA, Albariño CG, Lu JG, Radoshitzky SR, Salazar-Bravo J, Farzan M, Spiropoulou CF, Choe H. Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses. PLoS Pathog. 2009 Apr;5(4):e1000358. doi: 10.1371/journal.ppat.1000358. Epub 2009 Apr 3. PMID: 19343214 PMCID: PMC2658809  read article


Strang BL, Sinigalia E, Silva LA, Coen DM, Loregian A. Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84. J Virol. 2009 Aug;83(15):7581-9. doi: 10.1128/JVI.00663-09. Epub 2009 May 20. PMID: 19457994 PMCID: PMC2708651  read article


Hamirally S, Kamil JP, Ndassa-Colday YM, Lin AJ, Jahng WJ, Baek MC, Noton S, Silva LA, Simpson-Holley M, Knipe DM, Golan DE, Marto JA, Coen DM. Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress. PLoS Pathog. 2009 Jan;5(1):e1000275. doi: 10.1371/journal.ppat.1000275. Epub 2009 Jan 23. PMID: 19165338 PMCID: PMC2625439  read article


Zhou X, Spangle JM, Münger K. Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: is autophagy an "Achilles' heel" of human cancers? Autophagy. 2009 May;5(4):578-9. Epub 2009 May 6. PMID: 19333004 read article


Medoff BD, Seung E, Hong S, Thomas SY, Sandall BP, Duffield JS, Kuperman DA, Erle DJ, Luster AD. CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J Immunol. 2009 Jan 1;182(1):623-35. PMID: 19109196 PMCID: PMC2718444 read article


Aoki ST, Settembre EC, Trask SD, Greenberg HB, Harrison SC, Dormitzer PR. Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science. 2009 Jun 12;324(5933):1444-7. doi: 10.1126/science.1170481. PMID: 19520960 PMCID: PMC2995306  read article


Uzri D, Gehrke L. Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities. J Virol. 2009 May;83(9):4174-84. Epub 2009 Feb 18. PMID: 19224987 PMCID: PMC2668486 read article


Falbo KB, Alabert C, Katou Y, Wu S, Han J, Wehr T, Xiao J, He X, Zhang Z, Shi Y, Shirahige K, Pasero P, Shen X. Involvement of a chromatin remodeling complex in damage tolerance during DNA replication. Nat Struct Mol Biol. 2009 Nov;16(11):1167-72. doi: 10.1038/nsmb.1686. Epub 2009 Oct 25. PMID: 19855395 PMCID: PMC2974178  read article


Wu S, Hu YC, Liu H, Shi Y. Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis. Mol Cell Biol. 2009 Dec;29(23):6245-56. doi: 10.1128/MCB.00679-09. Epub 2009 Sep 28. PMID: 19786570 PMCID: PMC2786691  read article


Yoder JD, Trask SD, Vo TP, Binka M, Feng N, Harrison SC, Greenberg HB, Dormitzer PR. VP5* rearranges when rotavirus uncoats. J Virol. 2009 Nov;83(21):11372-7. doi: 10.1128/JVI.01228-09. Epub 2009 Aug 19. PMID: 19692464 PMCID: PMC2772785  read article


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2008


Arnold MM, Murray KE, Nibert ML. Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein mu NS during reovirus infection. Virology. 2008 Jun 5;375(2):412-23. Epub 2008 Apr 18. PMID: 18374384 PMCID: PMC2486453 read article


Rowley CF, Boutwell CL, Lockman S, Essex M. Improvement in allele-specific PCR assay with the use of polymorphism-specific primers for the analysis of minor variant drug resistance in HIV-1 subtype C. J Virol Methods. 2008 Apr;149(1):69-75. doi: 10.1016/j.jviromet.2008.01.005. Epub 2008 Mar 4. PMID: 18295909 PMCID: PMC2927209 read article


Brockman MA, Knipe DM. Herpes simplex virus as a tool to define the role of complement in the immune response to peripheral infection. Vaccine. 2008 Dec 30;26 Suppl 8:I94-9. PMID: 19388172 PMCID: PMC2742331  read article


Bryant KF, Macari ER, Malik N, Boyce M, Yuan J, Coen DM. ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells. Virology. 2008 Sep 30;379(2):197-204. doi: 10.1016/j.virol.2008.06.028. Epub 2008 Aug 6. PMID: 18684481 PMCID: PMC2665023  read article


Bryant KF, Coen DM. Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript. J Virol. 2008 Jan;82(1):77-85. Epub 2007 Oct 24. PMID: 17959669 PMCID: PMC2224361  read article


Day CL, Mkhwanazi N, Reddy S, Mncube Z, van der Stok M, Klenerman P, Walker BD. Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons. J Infect Dis. 2008 Apr 1;197(7):990-9. doi: 10.1086/529048. PMID: 18419535 read article


Ramduth D, Thobakgale CF, Mkhwanazi NP, De Pierres C, Reddy S, van der Stok M, Mncube Z, Mphatswe W, Blanckenberg N, Cengimbo A, Prendergast A, Tudor-Williams G, Dong K, Jeena P, Coovadia HM, Day CL, Kiepiela P, Goulder PJ, Walker BD. Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants. AIDS Res Hum Retroviruses. 2008 Feb;24(2):265-70. doi: 10.1089/aid.2007.0096. PMID: 18284325 read article


Ngumbela KC, Day CL, Mncube Z, Nair K, Ramduth D, Thobakgale C, Moodley E, Reddy S, de Pierres C, Mkhwanazi N, Bishop K, van der Stok M, Ismail N, Honeyborne I, Crawford H, Kavanagh DG, Rousseau C, Nickle D, Mullins J, Heckerman D, Korber B, Coovadia H, Kiepiela P, Goulder PJ, Walker BD. Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure. AIDS Res Hum Retroviruses. 2008 Jan;24(1):72-82. doi: 10.1089/aid.2007.0124. PMID: 18275350 read article


Erlandson KJ, Or E, Osborne AR, Rapoport TA. Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. J Biol Chem. 2008 Jun 6;283(23):15709-15. Epub 2008 Mar 21. PMID: 18359943 PMCID: PMC2409214 read article


Erlandson KJ, Miller SB, Nam Y, Osborne AR, Zimmer J, Rapoport TA. A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 2008 Oct 16;455(7215):984-7. PMID: 18923526


Fontaine-Rodriguez EC, Knipe DM. Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs. J Virol. 2008 Apr;82(7):3538-45. Epub 2008 Jan 23. PMID: 18216091 PMCID: PMC2268449 read article


Gomila RC, Gehrke L. Biochemical approaches for characterizing RNA-protein complexes in preparation for high resolution structure analysis. Methods Mol Biol. 2008;451:279-91. doi: 10.1007/978-1-59745-102-4_20. PMID: 18370263 read article


Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses. Clin Vaccine Immunol. 2008 Apr;15(4):691-6. Epub 2008 Feb 13. PMID: 18272665 PMCID: PMC2292663 read article


Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, van Rooijen N, Hovav AH, Letvin NL. CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses. Blood. 2008 Dec 1;112(12):4585-90. Epub 2008 Sep 10. PMID: 18784371 PMCID: PMC2597129 read article


He X, Fan HY, Garlick JD, Kingston RE. Diverse regulation of SNF2h chromatin remodeling by noncatalytic subunits. Biochemistry. 2008 Jul 8;47(27):7025-33. doi: 10.1021/bi702304p. Epub 2008 Jun 14. PMID: 18553938 read article


Huang IC, Li W, Sui J, Marasco W, Choe H, Farzan M. Influenza A virus neuraminidase limits viral superinfection. J Virol. 2008 May;82(10):4834-43. doi: 10.1128/JVI.00079-08. Epub 2008 Mar 5. PMID: 18321971 PMCID: PMC2346733 read article


Agosto MA, Myers KS, Ivanovic T, Nibert ML. A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10571-6. doi: 10.1073/pnas.0802039105. Epub 2008 Jul 24. PMID: 18653761 PMCID: PMC2492467 read article


Ivanovic T, Agosto MA, Zhang L, Chandran K, Harrison SC, Nibert ML. Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. EMBO J. 2008 Apr 23;27(8):1289-98. doi: 10.1038/emboj.2008.60. Epub 2008 Mar 27. PMID: 18369316 PMCID: PMC2367403  read article


Johnson KE, Song B, Knipe DM. Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. Virology. 2008 May 10;374(2):487-94. Epub 2008 Feb 14. PMID: 18279905 PMCID: PMC2638114 read article


Kuhn JH. (Co-editor and Contributor Kranzusch PJ pg 349). Filoviruses, A compendium of 40 years of epidemiological, clinical, and laboratory studies, Arch. Virol. Suppl. 20, 12-360. (2008) PMID: 18637412 read article


Laird ME, Igarashi T, Martin MA, Desrosiers RC. Importance of the V1/V2 loop region of simian-human immunodeficiency virus envelope glycoprotein gp120 in determining the strain specificity of the neutralizing antibody response. J Virol. 2008 Nov;82(22):11054-65. doi: 10.1128/JVI.01341-08. Epub 2008 Sep 3. PMID: 18768967 PMCID: PMC2573292  read article


Radoshitzky SR, Kuhn JH, Spiropoulou CF, Albariño CG, Nguyen DP, Salazar-Bravo J, Dorfman T, Lee AS, Wang E, Ross SR, Choe H, Farzan M. Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2664-9. Epub 2008 Feb 11. PMID: 18268337 PMCID: PMC2268193 read article


Mefford ME, Gorry PR, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues. AIDS Res Hum Retroviruses. 2008 Sep;24(9):1215-20. PMID: 18788913 PMCID: PMC2801411 read article


Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS One. 2008 Jun 25;3(6):e2516. PMID: 18575590 PMCID: PMC2424175 read article


Mirchandani KD, McCaffrey RM, D'Andrea AD. The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. DNA Repair (Amst). 2008 Jun 1;7(6):902-11. doi: 10.1016/j.dnarep.2008.03.001. Epub 2008 Apr 29. PMID: 18448394 PMCID: PMC2715953  read article


Li J, Rahmeh A, Morelli M, Whelan SP. A conserved motif in region v of the large polymerase proteins of nonsegmented negative-sense RNA viruses that is essential for mRNA capping. J Virol. 2008 Jan;82(2):775-84. Epub 2007 Nov 14. PMID: 18003731 PMCID: PMC2224588 read article


Agosto MA, Myers KS, Ivanovic T, Nibert ML. A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10571-6. doi: 10.1073/pnas.0802039105. Epub 2008 Jul 24. PMID: 18653761 PMCID: PMC2492467 read article


Nguyen CL, Münger K. Direct association of the HPV16 E7 oncoprotein with cyclin A/CDK2 and cyclin E/CDK2 complexes. Virology. 2008 Oct 10;380(1):21-5. Epub 2008 Aug 21. PMID: 18718623PMCID: PMC2574417 read article


Nguyen CL, McLaughlin-Drubin ME, Münger K. Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Res. 2008 Nov 1;68(21):8715-22. PMID: 18974113 PMCID: PMC2597155 read article


Nguyen CL, Münger K. Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1. J Virol. 2009 Feb;83(4):1700-7. Epub 2008 Dec 3. PMID: 19052088 PMCID: PMC2643759 read article


Diaz-Griffero F, Perron M, McGee-Estrada K, Hanna R, Maillard PV, Trono D, Sodroski J. A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus. Virology. 2008 Sep 1;378(2):233-42. doi: 10.1016/j.virol.2008.05.008. Epub 2008 Jun 30. PMID: 18586294 PMCID: PMC2597210  read article


Radoshitzky SR, Kuhn JH, Spiropoulou CF, Albariño CG, Nguyen DP, Salazar-Bravo J, Dorfman T, Lee AS, Wang E, Ross SR, Choe H, Farzan M. Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2664-9. doi: 10.1073/pnas.0709254105. Epub 2008 Feb 11. PMID: 18268337 PMCID: PMC2268193  read article


Campanella GS, Tager AM, El Khoury JK, Thomas SY, Abrazinski TA, Manice LA, Colvin RA, Luster AD. Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4814-9. doi: 10.1073/pnas.0801544105. Epub 2008 Mar 17. PMID: 18347328 PMCID: PMC2290783 read article


Medoff BD, Thomas SY, Luster AD. T cell trafficking in allergic asthma: the ins and outs. Annu Rev Immunol. 2008;26:205-32. doi: 10.1146/annurev.immunol.26.021607.090312. PMID: 18304002


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2007


Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, Clapham PR, Wolinsky SM, Crowe SM, Gabuzda D. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 2007 May 25;362(1):163-78. Epub 2007 Jan 18. PMID: 17239419 PMCID: PMC1973138  read article


Agopian K, Wei BL, Garcia JV, Gabuzda D. CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable. Virology. 2007 Feb 5;358(1):119-35. Epub 2006 Sep 18. PMID: 16979207 PMCID: PMC1995023  read article


Carvalho J, Arnold MM, Nibert ML. Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2. Virology. 2007 Aug 1;364(2):301-16. Epub 2007 Apr 23. PMID: 17451769 PMCID: PMC2486448 read article


Miller CL, Arnold MM, Broering TJ, Eichwald C, Kim J, Dinoso JB, Nibert ML. Virus-derived platforms for visualizing protein associations inside cells. Mol Cell Proteomics. 2007 Jun;6(6):1027-38. Epub 2007 Mar 5. PMID: 17339631


Boutwell CL, Essex M. Identification of HLA class I-associated amino acid polymorphisms in the HIV-1C proteome. AIDS Res Hum Retroviruses. 2007 Jan;23(1):165-74. PMID: 17263647 read article


Watanabe D, Brockman MA, Ndung'u T, Mathews L, Lucas WT, Murphy CG, Felber BK, Pavlakis GN, Deluca NA, Knipe DM. Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector. Virology. 2007 Jan 20;357(2):186-98. Epub 2006 Sep 22. PMID: 16996101  read article


Day CL, Kiepiela P, Leslie AJ, van der Stok M, Nair K, Ismail N, Honeyborne I, Crawford H, Coovadia HM, Goulder PJ, Walker BD, Klenerman P. Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection. J Virol. 2007 Jan;81(1):434-8. Epub 2006 Oct 18. PMID: 17050606 PMCID: PMC1797250 read article


Sterjovski J, Churchill MJ, Ellett A, Gray LR, Roche MJ, Dunfee RL, Purcell DF, Saksena N, Wang B, Sonza S, Wesselingh SL, Karlsson I, Fenyo EM, Gabuzda D, Cunningham AL, Gorry PR. Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS. Retrovirology. 2007 Dec 12;4:89. PMID: 18076768 PMCID: PMC2225424 read article


Dunfee RL, Thomas ER, Wang J, Kunstman K, Wolinsky SM, Gabuzda D. Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia. Virology. 2007 Oct 10;367(1):222-34. Epub 2007 Jun 27. PMID: 17599380 PMCID: PMC2201988
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Thomas ER, Dunfee RL, Stanton J, Bogdan D, Kunstman K, Wolinsky SM, Gabuzda D. High frequency of defective vpu compared with tat and rev genes in brain from patients with HIV type 1-associated dementia. AIDS Res Hum Retroviruses. 2007 Apr;23(4):575-80. PMID: 17451348
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Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, Clapham PR, Wolinsky SM, Crowe SM, Gabuzda D. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 2007 May 25;362(1):163-78. Epub 2007 Jan 18. PMID: 17239419 PMCID: PMC1973138
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Thomas ER, Dunfee RL, Stanton J, Bogdan D, Taylor J, Kunstman K, Bell JE, Wolinsky SM, Gabuzda D. Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion. Virology. 2007 Mar 30;360(1):105-19. Epub 2006 Nov 7. PMID: 17084877 PMCID: PMC1890014 read article


Saparov SM, Erlandson K, Cannon K, Schaletzky J, Schulman S, Rapoport TA, Pohl P. Determining the conductance of the SecY protein translocation channel for small molecules. Mol Cell. 2007 May 25;26(4):501-9. PMID: 17531809


Li W, Schulman S, Boyd D, Erlandson K, Beckwith J, Rapoport TA. The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Mol Cell. 2007 May 25;26(4):511-21. PMID: 17531810


Greenland JR, Letvin NL. Chemical adjuvants for plasmid DNA vaccines. Vaccine. 2007 May 10;25(19):3731-41. Epub 2007 Feb 20. Review. PMID: 17350735 read article


Greenland JR, Geiben R, Ghosh S, Pastor WA, Letvin NL. Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis. J Immunol. 2007 May 1;178(9):5652-8. PMID: 17442948 PMCID: PMC2262927 read article


Qin L, Greenland JR, Moriya C, Cayabyab MJ, Letvin NL. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo. J Virol. 2007 Oct;81(19):10606-13. Epub 2007 Jul 25. PMID: 17652387 PMCID: PMC2045443 read article


Li W, Sui J, Huang IC, Kuhn JH, Radoshitzky SR, Marasco WA, Choe H, Farzan M. The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2. Virology. 2007 Oct 25;367(2):367-74. Epub 2007 Jul 12. PMID: 17631932 PMCID: PMC2693060 read article


Ivanovic T, Agosto MA, Chandran K, Nibert ML. A role for molecular chaperone Hsc70 in reovirus outer capsid disassembly. J Biol Chem. 2007 Apr 20;282(16):12210-9. Epub 2007 Feb 6. PMID: 17284448 PMCID: PMC4822165 read article


Jarosinski K, Kattenhorn L, Kaufer B, Ploegh H, Osterrieder N. A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20025-30. Epub 2007 Dec 4. PMID: 18056809 PMCID: PMC2148416 read article


Schlieker C, Weihofen WA, Frijns E, Kattenhorn LM, Gaudet R, Ploegh HL. Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes. Mol Cell. 2007 Mar 9;25(5):677-87. PMID: 17349955 read article


Kelley-Clarke B, Ballestas ME, Srinivasan V, Barbera AJ, Komatsu T, Harris TA, Kazanjian M, Kaye KM. Determination of Kaposi's sarcoma-associated herpesvirus C-terminal latency-associated nuclear antigen residues mediating chromosome association and DNA binding. J Virol. 2007 Apr;81(8):4348-56. Epub 2007 Feb 7. PMID: 17287261 PMCID: PMC1866165 read article


Kelley-Clarke B, Ballestas ME, Komatsu T, Kaye KM. Kaposi's sarcoma herpesvirus C-terminal LANA concentrates at pericentromeric and peri-telomeric regions of a subset of mitotic chromosomes. Virology. 2007 Jan 20;357(2):149-57. Epub 2006 Sep 18. PMID: 16979209  read article


Balliet JW, Kushnir AS, Schaffer PA. Construction and characterization of a herpes simplex virus type I recombinant expressing green fluorescent protein: acute phase replication and reactivation in mice. Virology. 2007 May 10;361(2):372-83. Epub 2007 Jan 17. PMID: 17207829 PMCID: PMC1975764  read article


Laird ME, Desrosiers RC. Infectivity and neutralization of simian immunodeficiency virus with FLAG epitope insertion in gp120 variable loops. J Virol. 2007 Oct;81(20):10838-48. Epub 2007 Aug 8. PMID: 17686865 PMCID: PMC2045528


Link MA, Schaffer PA. Herpes simplex virus type 1 C-terminal variants of the origin binding protein (OBP), OBPC-1 and OBPC-2, cooperatively regulate viral DNA levels in vitro, and OBPC-2 affects mortality in mice. J Virol. 2007 Oct;81(19):10699-711. Epub 2007 Jul 18. PMID: 17634223 PMCID: PMC2045454  read article


Sen P, Charini WA, Subbramanian RA, Manuel ER, Kuroda MJ, Autissier PA, Letvin NL. Clonal focusing of epitope-specific CD8+ T lymphocytes in rhesus monkeys following vaccination and simian-human immunodeficiency virus challenge. J Virol. 2008 Jan;82(2):805-16. Epub 2007 Oct 31. PMID: 17977967 PMCID: PMC2224610 read article


Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, Clapham PR, Wolinsky SM, Crowe SM, Gabuzda D. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 2007 May 25;362(1):163-78. Epub 2007 Jan 18. PMID: 17239419 PMCID: PMC1973138 read article


Melroe GT, Silva L, Schaffer PA, Knipe DM. Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. Virology. 2007 Apr 10;360(2):305-21. Epub 2006 Nov 28. PMID: 17126870 PMCID: PMC1976290 read article


Nguyen CL, Eichwald C, Nibert ML, Münger K. Human papillomavirus type 16 E7 oncoprotein associates with the centrosomal component gamma-tubulin. J Virol. 2007 Dec;81(24):13533-43. Epub 2007 Oct 3. PMID: 17913829 PMCID: PMC2168839 read article


Diaz-Griffero F, Kar A, Perron M, Xiang SH, Javanbakht H, Li X, Sodroski J. Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain. J Virol. 2007 Oct;81(19):10362-78. Epub 2007 Jul 11. PMID: 17626085 PMCID: PMC2045480  read article


Ulm JW, Perron M, Sodroski J, C Mulligan R. Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction. Virology. 2007 Jul 5;363(2):245-55. Epub 2007 Mar 6. PMID: 17343889  read article


Perron MJ, Stremlau M, Lee M, Javanbakht H, Song B, Sodroski J. The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid. J Virol. 2007 Mar;81(5):2138-48. Epub 2006 Nov 29. PMID: 17135314 PMCID: PMC1865943  read article


Kuhn JH, Li W, Radoshitzky SR, Choe H, Farzan M. Severe acute respiratory syndrome coronavirus entry as a target of antiviral therapies. Antivir Ther. 2007;12(4 Pt B):639-50. PMID: 17944271  read article


Li W, Sui J, Huang IC, Kuhn JH, Radoshitzky SR, Marasco WA, Choe H, Farzan M. The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2. Virology. 2007 Oct 25;367(2):367-74. Epub 2007 Jul 12. PMID: 17631932 PMCID: PMC2693060 read article


Radoshitzky SR, Abraham J, Spiropoulou CF, Kuhn JH, Nguyen D, Li W, Nagel J, Schmidt PJ, Nunberg JH, Andrews NC, Farzan M, Choe H. Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature. 2007 Mar 1;446(7131):92-6. Epub 2007 Feb 7. PMID: 17287727 PMCID: PMC3197705  read article


Redd AD, Avalos A, Essex M. Infection of hematopoietic progenitor cells by HIV-1 subtype C, and its association with anemia in southern Africa. Blood. 2007 Nov 1;110(9):3143-9. Epub 2007 Aug 10. PMID: 17693583 PMCID: PMC2200905  read article


Redd AD, Avalos A, Phiri K, Essex M. Effects of HIV type 1 infection on hematopoiesis in Botswana. AIDS Res Hum Retroviruses. 2007 Aug;23(8):996-1003. PMID: 17725416  read article


Skaar JR, Florens L, Tsutsumi T, Arai T, Tron A, Swanson SK, Washburn MP, DeCaprio JA. PARC and CUL7 form atypical cullin RING ligase complexes. Cancer Res. 2007 Mar 1;67(5):2006-14. PMID: 17332328  read article


Smith JG, Cunningham JM. Receptor-induced thiolate couples Env activation to retrovirus fusion and infection. PLoS Pathog. 2007 Dec 21;3(12):e198. PubMed PMID: 18260686; PubMed Central PMCID: PMC2151085.


Bihl F, Narayan M, Chisholm JV 3rd, Henry LM, Suscovich TJ, Brown EE, Welzel TM, Kaufmann DE, Zaman TM, Dollard S, Martin JN, Wang F, Scadden DT, Kaye KM, Brander C. Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes. J Virol. 2007 May;81(9):4904-8. Epub 2007 Feb 28. PMID: 17329344 PMCID: PMC1900166 read article


Dodson AW, Taylor TJ, Knipe DM, Coen DM. Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach. Virology. 2007 Sep 30;366(2):340-8. Epub 2007 Jun 1.PMID: 17544048 PMCID: PMC2099250 read article


Thomas SY, Banerji A, Medoff BD, Lilly CM, Luster AD. Multiple chemokine receptors, including CCR6 and CXCR3, regulate antigen-induced T cell homing to the human asthmatic airway. J Immunol. 2007 Aug 1;179(3):1901-12. PMID: 17641057


Marcotte LL, Wass AB, Gohara DW, Pathak HB, Arnold JJ, Filman DJ, Cameron CE, Hogle JM. Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. J Virol. 2007 Apr;81(7):3583-96. Epub 2007 Jan 24. PMID: 17251299 PMCID: PMC1866080  read article


Wu S, Shi Y, Mulligan P, Gay F, Landry J, Liu H, Lu J, Qi HH, Wang W, Nickoloff JA, Wu C, Shi Y. A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat Struct Mol Biol. 2007 Dec;14(12):1165-72. Epub 2007 Nov 18. PMID: 18026119 PMCID: PMC2754171  read article


Cai Y, Jin J, Yao T, Gottschalk AJ, Swanson SK, Wu S, Shi Y, Washburn MP, Florens L, Conaway RC, Conaway JW. YY1 functions with INO80 to activate transcription. Nat Struct Mol Biol. 2007 Sep;14(9):872-4. Epub 2007 Aug 26. PMID: 17721549  read article


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2006


Agopian K, Wei BL, Garcia JV, Gabuzda D. A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. J Virol. 2006 Mar;80(6):3050-61. PMID: 16501114 PMCID: PMC1395437  read article


Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM. Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. J Biol Chem. 2006 Feb 24;281(8):5224-32. Epub 2005 Dec 20. PMID: 16371349 read article


Brockman MA, Verschoor A, Zhu J, Carroll MC, Knipe DM. Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells. J Virol. 2006 Jul;80(14):7111-7. PMID: 16809316 PMCID: PMC1489035  read article


Chen A, Zhao B, Kieff E, Aster JC, Wang F. EBNA-3B- and EBNA-3C-regulated cellular genes in Epstein-Barr virus-immortalized lymphoblastoid cell lines. J Virol. 2006 Oct;80(20):10139-50. PMID: 17005691 PMCID: PMC1617319  read article


Zhao B, Maruo S, Cooper A, R Chase M, Johannsen E, Kieff E, Cahir-McFarland E. RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1900-5. Epub 2006 Jan 30. PMID: 16446431 PMCID: PMC1413661. read article


Leslie A, Price DA, Mkhize P, Bishop K, Rathod A, Day C, Crawford H, Honeyborne I, Asher TE, Luzzi G, Edwards A, Rousseau CM, Mullins JI, Tudor-Williams G, Novelli V, Brander C, Douek DC, Kiepiela P, Walker BD, Goulder PJ. Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. J Immunol. 2006 Oct 1;177(7):4699-708. PMID: 16982909 read article


Wherry EJ, Day CL, Draenert R, Miller JD, Kiepiela P, Woodberry T, Brander C, Addo M, Klenerman P, Ahmed R, Walker BD. HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory. Virology. 2006 Sep 30;353(2):366-73. Epub 2006 Jul 24. PMID: 16860834 read article


Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006 Sep 21;443(7109):350-4. Epub 2006 Aug 20. PMID: 16921384  read article


Honeyborne I, Rathod A, Buchli R, Ramduth D, Moodley E, Rathnavalu P, Chetty S, Day C, Brander C, Hildebrand W, Walker BD, Kiepiela P, Goulder PJ. Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa. J Immunol. 2006 Apr 15;176(8):4699-705. PMID: 16585563  read article


Dunfee RL, Thomas ER, Gorry PR, Wang J, Taylor J, Kunstman K, Wolinsky SM, Gabuzda D. The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15160-5. Epub 2006 Oct 2. PMID: 17015824 PMCID: PMC1586182
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Dunfee R, Thomas ER, Gorry PR, Wang J, Ancuta P, Gabuzda D. Mechanisms of HIV-1 neurotropism. Curr HIV Res. 2006 Jul;4(3):267-78. PMID: 16842080  read article


He X, Fan HY, Narlikar GJ, Kingston RE. Human ACF1 alters the remodeling strategy of SNF2h. J Biol Chem. 2006 Sep 29;281(39):28636-47. Epub 2006 Jul 29. PMID: 16877760
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Huang IC, Bosch BJ, Li W, Farzan M, Rottier PM, Choe H. SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry. Adv Exp Med Biol. 2006;581:335-8. PMID: 17037556  read article


Li W, Wong SK, Li F, Kuhn JH, Huang IC, Choe H, Farzan M. Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions. J Virol. 2006 May;80(9):4211-9. PMID: 16611880 PMCID: PMC1472041 read article


Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H. SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem. 2006 Feb 10;281(6):3198-203. Epub 2005 Dec 8. PMID: 16339146
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MacConaill LE, Hughes CM, Rozenblatt-Rosen O, Nannepaga S, Meyerson M. Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583. Mol Cancer Res. 2006 Oct;4(10):793-801. PMID: 17050672  read article


Agosto MA, Ivanovic T, Nibert ML. Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16496-501. Epub 2006 Oct 19. PMID: 17053074 PMCID: PMC1637610 read article


Wang J, Loveland AN, Kattenhorn LM, Ploegh HL, Gibson W. High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: mutant viruses altered in its active-site cysteine or histidine are viable. J Virol. 2006 Jun;80(12):6003-12. PMID: 16731939 PMCID: PMC1472576 read article


Barbera AJ, Chodaparambil JV, Kelley-Clarke B, Luger K, Kaye KM. Kaposi's sarcoma-associated herpesvirus LANA hitches a ride on the chromosome. Cell Cycle. 2006 May;5(10):1048-52. Epub 2006 May 15. PMID: 16721045 read article


Barbera AJ, Chodaparambil JV, Kelley-Clarke B, Joukov V, Walter JC, Luger K, Kaye KM. The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science. 2006 Feb 10;311(5762):856-61. PMID:16469929 read article


Cho NH, Kingston D, Chang H, Kwon EK, Kim JM, Lee JH, Chu H, Choi MS, Kim IS, Jung JU. Association of herpesvirus saimiri tip with lipid raft is essential for downregulation of T-cell receptor and CD4 coreceptor. J Virol. 2006 Jan;80(1):108-18. PMID: 16352535 PMCID: PMC1317525 read article


Orlando JS, Balliet JW, Kushnir AS, Astor TL, Kosz-Vnenchak M, Rice SA, Knipe DM, Schaffer PA. ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions. J Virol. 2006 Oct;80(19):9381-90. PMID: 16973544 PMCID: PMC1617265  read article


LaBonte ML, McKay PF, Letvin NL. Evidence of NK cell dysfunction in SIV-infected rhesus monkeys: impairment of cytokine secretion and NKG2C/C2 expression. Eur J Immunol. 2006 Sep;36(9):2424-33. PMID: 16906533


Manuel ER, Charini WA, Sen P, Peyerl FW, Kuroda MJ, Schmitz JE, Autissier P, Sheeter DA, Torbett BE, Letvin NL. Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses. J Virol. 2006 Dec;80(24):12032-40. Epub 2006 Oct 11. PMID: 17035327 PMCID: PMC1676269 read article


Mirchandani KD, D'Andrea AD. The Fanconi anemia/BRCA pathway: a coordinator of cross-link repair. Exp Cell Res. 2006 Aug 15;312(14):2647-53. Epub 2006 Jun 21. PMID: 16859679  read article


Huang TT, Nijman SM, Mirchandani KD, Galardy PJ, Cohn MA, Haas W, Gygi SP, Ploegh HL, Bernards R, D'Andrea AD. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat Cell Biol. 2006 Apr;8(4):339-47. Epub 2006 Mar 12. PMID: 16531995  read article


Javanbakht H, An P, Gold B, Petersen DC, O'Huigin C, Nelson GW, O'Brien SJ, Kirk GD, Detels R, Buchbinder S, Donfield S, Shulenin S, Song B, Perron MJ, Stremlau M, Sodroski J, Dean M, Winkler C. Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection. Virology. 2006 Oct 10;354(1):15-27. Epub 2006 Aug 2. PMID: 16887163  read article


Li X, Li Y, Stremlau M, Yuan W, Song B, Perron M, Sodroski J. Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains. J Virol. 2006 Jul;80(13):6198-206. PMID: 16775307 PMCID: PMC1488960  read article


Perron MJ, Stremlau M, Sodroski J. Two surface-exposed elements of the B30.2/SPRY domain as potency determinants of N-tropic murine leukemia virus restriction by human TRIM5alpha. J Virol. 2006 Jun;80(11):5631-6. PMID: 16699044 PMCID: PMC1472168  read article


Si Z, Vandegraaff N, O'huigin C, Song B, Yuan W, Xu C, Perron M, Li X, Marasco WA, Engelman A, Dean M, Sodroski J. Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7454-9. Epub 2006 Apr 28. PMID: 16648259 PMCID: PMC1464360  read article


Stremlau M, Song B, Javanbakht H, Perron M, Sodroski J. Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1. Virology. 2006 Jul 20;351(1):112-20. Epub 2006 Apr 27. PMID: 16643975 read article


Stremlau M, Perron M, Lee M, Li Y, Song B, Javanbakht H, Diaz-Griffero F, Anderson DJ, Sundquist WI, Sodroski J. Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5514-9. Epub 2006 Mar 15. MID: 16540544 PMCID: PMC1459386  read article


Poulin DL, DeCaprio JA. Is there a role for SV40 in human cancer? J Clin Oncol. 2006 Sep 10;24(26):4356-65. PMID: 16963733


Poulin DL, DeCaprio JA. The carboxyl-terminal domain of large T antigen rescues SV40 host range activity in trans independent of acetylation. Virology. 2006 May 25;349(1):212-21. Epub 2006 Feb 28. PMID: 16510165


Kuhn JH, Radoshitzky SR, Guth AC, Warfield KL, Li W, Vincent MJ, Towner JS, Nichol ST, Bavari S, Choe H, Aman MJ, Farzan M. Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor. J Biol Chem. 2006 Jun 9;281(23):15951-8. Epub 2006 Apr 4. PMID: 16595665 read article


Khan IA, Thomas SY, Moretto MM, Lee FS, Islam SA, Combe C, Schwartzman JD, Luster AD. CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection. PLoS Pathog. 2006 Jun;2(6):e49. Epub 2006 Jun 9. PMID: 16789839 PMCID: PMC1475660  read article


Thomas SY, Lilly CM, Luster AD. Invariant natural killer T cells in bronchial asthma. N Engl J Med. 2006 Jun 15;354(24):2613-6; author reply 2613-6. PMID: 16775244


Mikhak Z, Fleming CM, Medoff BD, Thomas SY, Tager AM, Campanella GS, Luster AD. STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells. J Immunol. 2006 Apr 15;176(8):4959-67. PMID: 16585592


Islam SA, Thomas SY, Hess C, Medoff BD, Means TK, Brander C, Lilly CM, Tager AM, Luster AD. The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans. Blood. 2006 Jan 15;107(2):444-53. Epub 2005 Sep 22. PMID: 16179368 PMCID: PMC1490027  read article


Affar el B, Gay F, Shi Y, Liu H, Huarte M, Wu S, Collins T, Li E, Shi Y. Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression. Mol Cell Biol. 2006 May;26(9):3565-81. PMID: 16611997 PMCID: PMC1447422  read article


Yoder JD, Dormitzer PR. Alternative intermolecular contacts underlie the rotavirus VP5* two- to three-fold rearrangement. EMBO J. 2006 Apr 5;25(7):1559-68. Epub 2006 Mar 2. PMID: 16511559 PMCID: PMC1440311  read article


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2005


Broering TJ, Arnold MM, Miller CL, Hurt JA, Joyce PL, Nibert ML. Carboxyl-proximal regions of reovirus nonstructural protein muNS necessary and sufficient for forming factory-like inclusions. J Virol. 2005 May;79(10):6194-206. PMID: 15858004 PMCID: PMC1091696 read article


Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM. Binding of herpes simplex virus-1 US11 to specific RNA sequences. Nucleic Acids Res. 2005 Oct 24;33(19):6090-100. Print 2005. PMID: 16246910 PMCID: PMC1266072  read article


Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress Science. 2005 Feb 11;307(5711):935-9. PMID: 15705855  read article


Chen A, Divisconte M, Jiang X, Quink C, Wang F. Epstein-Barr virus with the latent infection nuclear antigen 3B completely deleted is still competent for B-cell growth transformation in vitro. J Virol. 2005 Apr;79(7):4506-9. PMID: 15767450 PMCID: PMC1061580  read article


Maruo S, Johannsen E, Illanes D, Cooper A, Zhao B, Kieff E. Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical. J Virol. 2005 Aug;79(16):10171-9. PMID: 16051810 PMCID: PMC1182629. read article


Schott DH, Cureton DK, Whelan SP, Hunter CP. An antiviral role for the RNA interference machinery in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18420-4. Epub 2005 Dec 9. PMID: 16339901 PMCID: PMC1317933  read article


Ramduth D, Chetty P, Mngquandaniso NC, Nene N, Harlow JD, Honeyborne I, Ntumba N, Gappoo S, Henry C, Jeena P, Addo MM, Altfeld M, Brander C, Day C, Coovadia H, Kiepiela P, Goulder P, Walker B. Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses. J Infect Dis. 2005 Nov 1;192(9):1588-96. Epub 2005 Sep 30 .PMID: 16206073 read article


Lauer GM, Lucas M, Timm J, Ouchi K, Kim AY, Day CL, Schulze Zur Wiesch J, Paranhos-Baccala G, Sheridan I, Casson DR, Reiser M, Gandhi RT, Li B, Allen TM, Chung RT, Klenerman P, Walker BD. Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy. J Virol. 2005 Oct;79(20):12979-88. PMID: 16189000 PMCID: PMC1235828 read article


Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol. 2005 Sep 15;175(6):3603-13. PMID: 16148104 read article


Li J, Fontaine-Rodriguez EC, Whelan SP. Amino acid residues within conserved domain VI of the vesicular stomatitis virus large polymerase protein essential for mRNA cap methyltransferase activity. J Virol. 2005 Nov;79(21):13373-84. PMID: 16227259 PMCID: PMC1262600 read article


Greenland JR, Liu H, Berry D, Anderson DG, Kim WK, Irvine DJ, Langer R, Letvin NL. Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Mol Ther. 2005 Jul;12(1):164-70. PMID: 15963932 read article


Hershberger KL, Kurian J, Korber BT, Letvin NL. Killer cell immunoglobulin-like receptors (KIR) of the African-origin sabaeus monkey: evidence for recombination events in the evolution of KIR. Eur J Immunol. 2005 Mar;35(3):922-35. PMID: 15714591


Li W, Zhang C, Sui J, Kuhn JH, Moore MJ, Luo S, Wong SK, Huang IC, Xu K, Vasilieva N, Murakami A, He Y, Marasco WA, Guan Y, Choe H, Farzan M. Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J. 2005 Apr 20;24(8):1634-43. Epub 2005 Mar 24. PMID: 15791205 PMCID: PMC1142572
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Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK. Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14659-64. Epub 2005 Sep 29. PMID: 16195383 PMCID: PMC1253549 read article


Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):749-54. Epub 2005 Jan 7. PMID: 15640349 PMCID: PMC545577
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Rozenblatt-Rosen O, Hughes CM, Nannepaga SJ, Shanmugam KS, Copeland TD, Guszczynski T, Resau JH, Meyerson M. The parafibromin tumor suppressor protein is part of a human Paf1 complex. Mol Cell Biol. 2005 Jan;25(2):612-20. PMID: 15632063 PMCID: PMC543415 read article


Jackson SS, Ilyinskii P, Philippon V, Gritz L, Yafal AG, Zinnack K, Beaudry KR, Manson KH, Lifton MA, Kuroda MJ, Letvin NL, Mazzara GP, Panicali DL. Role of genes that modulate host immune responses in the immunogenicity and pathogenicity of vaccinia virus. J Virol. 2005 May;79(10):6554-9. PubMed PMID: 15858042; PubMed Central PMCID: PMC1091706.


Jackson SS, Schmitz JE, Kuroda MJ, McKay PF, Sumida SM, Martin KL, Yu F, Lifton MA, Gorgone DA, Letvin NL. Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes. Immunology. 2005 Dec;116(4):443-53. PubMed PMID: 16313358; PubMed Central PMCID: PMC1802447.


Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM. Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16055-9. Epub 2005 Oct 24. PMID: 16247011 PMCID: PMC1266038 read article


Schlieker C, Korbel GA, Kattenhorn LM, Ploegh HL. A deubiquitinating activity is conserved in the large tegument protein of the herpesviridae. J Virol. 2005 Dec;79(24):15582-5. PMID: 16306630 PMCID: PMC1316044
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Kattenhorn LM, Korbel GA, Kessler BM, Spooner E, Ploegh HL. A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae. Mol Cell. 2005 Aug 19;19(4):547-57. PMID: 16109378  read article


Chang H, Gwack Y, Kingston D, Souvlis J, Liang X, Means RE, Cesarman E, Hutt-Fletcher L, Jung JU. Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA. J Virol. 2005 Apr;79(8):4651-63. PMID: 15795251 PMCID: PMC1069543 read article


Feng H, Zhang D, Palliser D, Zhu P, Cai S, Schlesinger A, Maliszewski L, Lieberman J. Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. J Immunol. 2005 Jul 1;175(1):421-32. PMID: 15972676  read article


Lee SK, Dykxhoorn DM, Kumar P, Ranjbar S, Song E, Maliszewski LE, François-Bongarçon V, Goldfeld A, Swamy NM, Lieberman J, Shankar P. Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood. 2005 Aug 1;106(3):818-26. Epub 2005 Apr 14. PMID: 15831707 PMCID: PMC1895148  read article


LaVail JH, Tauscher AN, Hicks JW, Harrabi O, Melroe GT, Knipe DM. Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons. J Virol. 2005 Sep;79(17):11142-50. PMID: 16103165 PMCID: PMC1193612  read article


Song B, Javanbakht H, Perron M, Park DH, Stremlau M, Sodroski J. Retrovirus restriction by TRIM5alpha variants from Old World and New World primates. J Virol. 2005 Apr;79(7):3930-7. PMID: 15767395 PMCID: PMC1061569  read article


Stremlau M, Perron M, Welikala S, Sodroski J. Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction. J Virol. 2005 Mar;79(5):3139-45 PMID: 15709033 PMCID: PMC548447  read article


Song B, Diaz-Griffero F, Park DH, Rogers T, Stremlau M, Sodroski J. TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity. Virology. 2005 Dec 20;343(2):201-11. Epub 2005 Sep 22. PMID: 16183097


Skaar JR, Arai T, DeCaprio JA. Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development. Mol Cell Biol. 2005 Jul;25(13):5579-89. PMID: 15964813 PMCID: PMC1156978  read article


Woodberry T, Suscovich TJ, Henry LM, Davis JK, Frahm N, Walker BD, Scadden DT, Wang F, Brander C. Differential targeting and shifts in the immunodominance of Epstein-Barr virus--specific CD8 and CD4 T cell responses during acute and persistent infection. J Infect Dis. 2005 Nov 1;192(9):1513-24. Epub 2005 Sep 26. PMID: 16206065


Woodberry T, Suscovich TJ, Henry LM, Martin JN, Dollard S, O'Connor PG, Davis JK, Osmond D, Lee TH, Kedes DH, Khatri A, Lee J, Walker BD, Scadden DT, Brander C. Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins. J Infect Dis. 2005 Aug 15;192(4):622-9. Epub 2005 Jul 15. PMID: 16028131


Olesky M, McNamee EE, Zhou C, Taylor TJ, Knipe DM. Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins. Virology. 2005 Jan 5;331(1):94-105. PMID: 15582656


Medoff BD, Thomas SY, Banerji A, Wain JC, Zhang H, Lilly CM, Ginns LC, Luster AD. Pathogenic T-cell recruitment into the airway in human disease. Ann N Y Acad Sci. 2005 Dec;1062:220-41. PMID: 16461804


Bromley SK, Thomas SY, Luster AD. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat Immunol. 2005 Sep;6(9):895-901. Epub 2005 Aug 14. PMID: 16116469


Medoff BD, Seung E, Wain JC, Means TK, Campanella GS, Islam SA, Thomas SY, Ginns LC, Grabie N, Lichtman AH, Tager AM, Luster AD. BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation. J Exp Med. 2005 Jul 4;202(1):97-110. PMID: 15998790 PMCID: PMC2212891 read article


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2004


Loregian A, Appleton BA, Hogle JM, Coen DM. Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit. J Virol. 2004 Sep;78(17):9084-92. PMID: 15308704 PMCID: PMC506919  read article


Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM. The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer. Mol Cell. 2004 Jul 23;15(2):233-44. PMID: 15260974 read article


Loregian A, Appleton BA, Hogle JM, Coen DM. Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44. J Virol. 2004 Jan;78(1):158-67. PMID: 14671097 PMCID: PMC303418 read article


Yin P, Keirstead ND, Broering TJ, Arnold MM, Parker JS, Nibert ML, Coombs KM. Comparisons of the M1 genome segments and encoded mu2 proteins of different reovirus isolates. Virol J. 2004 Sep 23;1:6. PMID: 15507160 PMCID: PMC524354 read article


Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, Bronson R, Arnold MM, Knipe DM, Finberg RW. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1315-20. Epub 2004 Jan 22. PMID: 14739339 PMCID: PMC337050 read article


Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, Rathnavalu P, Moore C, Pfafferott KJ, Hilton L, Zimbwa P, Moore S, Allen T, Brander C, Addo MM, Altfeld M, James I, Mallal S, Bunce M, Barber LD, Szinger J, Day C, Klenerman P, Mullins J, Korber B, Coovadia HM, Walker BD, Goulder PJ. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature. 2004 Dec 9;432(7018):769-75. PMID 15592417 read article


Lauer GM, Barnes E, Lucas M, Timm J, Ouchi K, Kim AY, Day CL, Robbins GK, Casson DR, Reiser M, Dusheiko G, Allen TM, Chung RT, Walker BD, Klenerman P. High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. Gastroenterology. 2004 Sep;127(3):924-36. PMID: 15362047 read article


Fontaine-Rodriguez EC, Taylor TJ, Olesky M, Knipe DM. Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. Virology. 2004 Dec 20;330(2):487-92. PMID: 15567442 read article


Hughes CM, Rozenblatt-Rosen O, Milne TA, Copeland TD, Levine SS, Lee JC, Hayes DN, Shanmugam KS, Bhattacharjee A, Biondi CA, Kay GF, Hayward NK, Hess JL, Meyerson M. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol Cell. 2004 Feb 27;13(4):587-97. PMID:
14992727
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Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, Lee JC, Hughes CM, Shanmugam KS, Bhattacharjee A, Meyerson M, Collins FS. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1892-7. Epub 2004 Feb 9. PMID: 14769924 PMCID: PMC357023 read article


Seaman MS, Peyerl FW, Jackson SS, Lifton MA, Gorgone DA, Schmitz JE, Letvin NL. Subsets of memory cytotoxic T lymphocytes elicited by vaccination influence the efficiency of secondary expansion in vivo. J Virol. 2004 Jan;78(1):206-15. PubMed PMID: 14671102; PubMed Central PMCID: PMC303428.


Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol. 2004 Mar;78(6):2666-73. PubMed PMID: 14990686; PubMed Central PMCID: PMC353774.


McKay PF, Barouch DH, Santra S, Sumida SM, Jackson SS, Gorgone DA, Lifton MA, Letvin NL. Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses. Eur J Immunol. 2004 Apr;34(4):1011-20. PubMed PMID: 15048711.


Sumida SM, McKay PF, Truitt DM, Kishko MG, Arthur JC, Seaman MS, Jackson SS, Gorgone DA, Lifton MA, Letvin NL, Barouch DH. Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines. J Clin Invest. 2004 Nov;114(9):1334-42. PubMed PMID: 15520866; PubMed Central PMCID: PMC524232.


Peacock JW, Nordone SK, Jackson SS, Liao HX, Letvin NL, Yafal AG, Gritz L, Mazzara GP, Haynes BF, Staats HF. Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting. J Virol. 2004 Dec;78(23):13163-72. PubMed PMID: 15542668; PubMed Central PMCID: PMC524967.


Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol. 2004 Mar;78(6):2666-73. PubMed PMID: 14990686; PubMed Central PMCID: PMC353774.


Kattenhorn LM, Mills R, Wagner M, Lomsadze A, Makeev V, Borodovsky M, Ploegh HL, Kessler BM. Identification of proteins associated with murine cytomegalovirus virions. J Virol. 2004 Oct;78(20):11187-97. PMID: 15452238 PMCID: PMC521832
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Komatsu T, Ballestas ME, Barbera AJ, Kelley-Clarke B, Kaye KM. KSHV LANA1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA binding, replication, and episome persistence. Virology. 2004 Feb 20;319(2):225-36. PMID: 14980483 read article


Labonte ML, Letvin NL. Variable NKG2 expression in the peripheral blood lymphocytes of rhesus monkeys. Clin Exp Immunol. 2004 Nov;138(2):205-12. PMID: 15498028 PMCID: PMC1809222 read article


LaBonte ML, Choi EI, Letvin NL. Molecular determinants regulating the pairing of NKG2 molecules with CD94 for cell surface heterodimer expression. J Immunol. 2004 Jun 1;172(11):6902-12. PMID: 15153509


Melroe GT, DeLuca NA, Knipe DM. Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J Virol. 2004 Aug;78(16):8411-20. PMID: 15280450 PMCID: PMC479070 read article


Helander A, Miller CL, Myers KS, Neutra MR, Nibert ML. Protective immunoglobulin A and G antibodies bind to overlapping intersubunit epitopes in the head domain of type 1 reovirus adhesin sigma1. J Virol. 2004 Oct;78(19):10695-705. PMID: 15367636 PMCID: PMC516417 read article


Münger K, Baldwin A, Edwards KM, Hayakawa H, Nguyen CL, Owens M, Grace M, Huh K. Mechanisms of human papillomavirus-induced oncogenesis. J Virol. 2004 Nov;78(21):11451-60. Review. PMID: 15479788 PMCID: PMC523272 read article


Perron MJ, Stremlau M, Song B, Ulm W, Mulligan RC, Sodroski J. TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11827-32. Epub 2004 Jul 27. PMID: 15280539 PMCID: PMC511059  read article


Owens CM, Song B, Perron MJ, Yang PC, Stremlau M, Sodroski J. Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid. J Virol. 2004 May;78(10):5423-37. PMID: 15113921 PMCID: PMC400345  read article


Stremlau M, Owens CM, Perron MJ, Kiessling M, Autissier P, Sodroski J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature. 2004 Feb 26;427(6977):848-53. PMID: 14985764  read article


Poulin DL, Kung AL, DeCaprio JA. p53 targets simian virus 40 large T antigen for acetylation by CBP. J Virol. 2004 Aug;78(15):8245-53. PMID: 15254196 PMCID: PMC446111 read article


Buchmann AM, Skaar JR, DeCaprio JA. Activation of a DNA damage checkpoint response in a TAF1-defective cell line. Mol Cell Biol. 2004 Jun;24(12):5332-9. PMID: 15169897 PMCID: PMC419897  read article


Smith JG, Mothes W, Blacklow SC, Cunningham JM. The mature avian leucosis virus subgroup A envelope glycoprotein is metastable, and refolding induced by the synergistic effects of receptor binding and low pH is coupled to infection. J Virol. 2004 Feb;78(3):1403-10. PubMed PMID: 14722295; PubMed Central PMCID: PMC321377.


Suscovich TJ, Paulose-Murphy M, Harlow JD, Chen Y, Thomas SY, Mellott TJ, Walker BD, Scadden DT, Zeichner S, Brander C. Defective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles. Leuk Lymphoma. 2004 Jun;45(6):1223-38. PMID: 15360006


Fontaine-Rodriguez EC, Taylor TJ, Olesky M, Knipe DM. Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. Virology. 2004 Dec 20;330(2):487-92. PMID: 15567442


Taylor TJ, Knipe DM. Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. J Virol. 2004 Jun;78(11):5856-66. PMID: 15140983 PMCID: PMC415816 read article


Hess C, Altfeld M, Thomas SY, Addo MM, Rosenberg ES, Allen TM, Draenert R, Eldrige RL, van Lunzen J, Stellbrink HJ, Walker BD, Luster AD. HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication. Lancet. 2004 Mar 13;363(9412):863-6. PMID: 15031033


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2003


Miller CL, Broering TJ, Parker JS, Arnold MM, Nibert ML. Reovirus sigma NS protein localizes to inclusions through an association requiring the mu NS amino terminus. J Virol. 2003 Apr;77(8):4566-76. PMID: 12663763 PMCID: PMC152138 read article


Verschoor A, Brockman MA, Gadjeva M, Knipe DM, Carroll MC. Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection. J Immunol. 2003 Nov 15;171(10):5363-71. PMID: 14607939  read article


Maruo S, Johannsen E, Illanes D, Cooper A, Kieff E. Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth. J Virol. 2003 Oct;77(19):10437-47. PMID: 12970429 PMCID: PMC228516 read article


Cooper A, Johannsen E, Maruo S, Cahir-McFarland E, Illanes D, Davidson D, Kieff E. EBNA3A association with RBP-Jkappa down-regulates c-myc and Epstein-Barr virus-transformed lymphoblast growth. J Virol. 2003 Jan;77(2):999-1010. PMID: 12502816 PMCID: PMC140836. read article


Day CL, Walker BD. Progress in defining CD4 helper cell responses in chronic viral infections. J Exp Med. 2003 Dec 15;198(12):1773-7. PMID: 14676292 PMCID: PMC2194149  read article


Day CL, Seth NP, Lucas M, Appel H, Gauthier L, Lauer GM, Robbins GK, Szczepiorkowski ZM, Casson DR, Chung RT, Bell S, Harcourt G, Walker BD, Klenerman P, Wucherpfennig KW. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest. 2003 Sep;112(6):831-42. PMID: 12975468 PMCID: PMC193667 read article


Somsouk M, Lauer GM, Casson D, Terella A, Day CL, Walker BD, Chung RT. Spontaneous resolution of chronic hepatitis C virus disease after withdrawal of immunosuppression. Gastroenterology. 2003 Jun;124(7):1946-9. PMID: 12806627 read article


Fan HY, He X, Kingston RE, Narlikar GJ. Distinct strategies to make nucleosomal DNA accessible. Mol Cell. 2003 May;11(5):1311-22. PMID: 12769854


Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA, Lifton MA, Chakrabarti BK, Xu L, Nabel GJ, Letvin NL. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol. 2003 Aug;77(16):8729-35. PubMed PMID: 12885892; PubMed Central PMCID: PMC167238.


Arai T, Kasper JS, Skaar JR, Ali SH, Takahashi C, DeCaprio JA. Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9855-60. Epub 2003 Aug 6. PMID: 12904573 PMCID: PMC187864  read article


Thomas SM, Zeng Q, Dyer KF, Suscovich TJ, Kanter PM, Whalen JD, Watkins SF, Grandis JR. Tissue distribution of liposome-mediated epidermal growth factor receptor antisense gene therapy. Cancer Gene Ther. 2003 Jul;10(7):518-28. PMID: 12833132


Taylor TJ, McNamee EE, Day C, Knipe DM. Herpes simplex virus replication compartments can form by coalescence of smaller compartments. Virology. 2003 May 10;309(2):232-47. PMID: 12758171


Taylor TJ, Knipe DM. C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization. Virology. 2003 May 10;309(2):219-31. PMID: 12758170


Thomas SY, Hou R, Boyson JE, Means TK, Hess C, Olson DP, Strominger JL, Brenner MB, Gumperz JE, Wilson SB, Luster AD. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. J Immunol. 2003 Sep 1;171(5):2571-80. PMID: 12928408


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2002


Gadjeva M, Verschoor A, Brockman MA, Jezak H, Shen LM, Knipe DM, Carroll MC. Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice. J Immunol. 2002 Nov 15;169(10):5489-95. PMID: 12421924  read article


Brockman MA, Knipe DM. Herpes simplex virus vectors elicit durable immune responses in the presence of preexisting host immunity. J Virol. 2002 Apr;76(8):3678-87. PMID: 11907207 PMCID: PMC136066  read article


Taylor TJ, Brockman MA, McNamee EE, Knipe DM. Herpes simplex virus. Front Biosci. 2002 Mar 1;7:d752-64. PMID: 11861220 read article


Lauer GM, Ouchi K, Chung RT, Nguyen TN, Day CL, Purkis DR, Reiser M, Kim AY, Lucas M, Klenerman P, Walker BD. Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities. J Virol. 2002 Jun;76(12):6104-13. PMID: 12021343 PMCID: PMC136241 read article


Lauer GM, Nguyen TN, Day CL, Robbins GK, Flynn T, McGowan K, Rosenberg ES, Lucas M, Klenerman P, Chung RT, Walker BD. Human immunodeficiency virus type 1-hepatitis C virus coinfection: intraindividual comparison of cellular immune responses against two persistent viruses. J Virol. 2002 Mar;76(6):2817-26. PMID: 11861849 PMCID: PMC135971 read article


Barouch DH, Santra S, Tenner-Racz K, Racz P, Kuroda MJ, Schmitz JE, Jackson SS, Lifton MA, Freed DC, Perry HC, Davies ME, Shiver JW, Letvin NL. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. J Immunol. 2002 Jan 15;168(2):562-8. PubMed PMID: 11777947.


Taylor TJ, Brockman MA, McNamee EE, Knipe DM. Herpes simplex virus. Front Biosci. 2002 Mar 1;7:d752-64. PMID: 11861220


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2001


Verschoor A, Brockman MA, Knipe DM, Carroll MC. Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection. J Immunol. 2001 Sep 1;167(5):2446-51. PMID: 11509581  read article


Day CL, Shea AK, Altfeld MA, Olson DP, Buchbinder SP, Hecht FM, Rosenberg ES, Walker BD, Kalams SA. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J Virol. 2001 Jul;75(14):6279-91. PMID: 11413294 PMCID: PMC114350  read article


LaBonte ML, Hershberger KL, Korber B, Letvin NL. The KIR and CD94/NKG2 families of molecules in the rhesus monkey. Immunol Rev. 2001 Oct;183:25-40. PMID: 11782245


Hershberger KL, Shyam R, Miura A, Letvin NL. Diversity of the killer cell Ig-like receptors of rhesus monkeys. J Immunol. 2001 Apr 1;166(7):4380-90. PMID: 11254692


Staats HF, Bradney CP, Gwinn WM, Jackson SS, Sempowski GD, Liao HX, Letvin NL, Haynes BF. Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization. J Immunol. 2001 Nov 1;167(9):5386-94. PubMed PMID: 11673557.


LaBonte ML, Hershberger KL, Korber B, Letvin NL. The KIR and CD94/NKG2 families of molecules in the rhesus monkey. Immunol Rev. 2001 Oct;183:25-40. PMID: 11782245


Brander C, O'Connor P, Suscovich T, Jones NG, Lee Y, Kedes D, Ganem D, Martin J, Osmond D, Southwood S, Sette A, Walker BD, Scadden DT. Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein. J Infect Dis. 2001 Jul 15;184(2):119-26. Epub 2001 Jun 18. PMID: 11424007


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2000


Da Costa X, Kramer MF, Zhu J, Brockman MA, Knipe DM. Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2. J Virol. 2000 Sep;74(17):7963-71. PMID: 10933704 PMCID: PMC112327  read article


Etemad-Moghadam B, Sun Y, Nicholson EK, Fernandes M, Liou K, Gomila R, Lee J, Sodroski J. Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo. J Virol. 2000 May;74(9):4433-40. PMID: 10756060 PMCID: PMC111962 read article


Santra S, Barouch DH, Jackson SS, Kuroda MJ, Schmitz JE, Lifton MA, Sharpe AH, Letvin NL. Functional equivalency of B7-1 and B7-2 for costimulating plasmid DNA vaccine-elicited CTL responses. J Immunol. 2000 Dec 15;165(12):6791-5. PubMed PMID: 11120800.


LaBonte ML, Levy DB, Letvin NL. Characterization of rhesus monkey CD94/NKG2 family members and identification of novel transmembrane-deleted forms of NKG2-A, B, C, and D. Immunogenetics. 2000 May;51(6):496-9. PMID: 10866118


Brander C, Suscovich T, Lee Y, Nguyen PT, O'Connor P, Seebach J, Jones NG, van Gorder M, Walker BD, Scadden DT. Impaired CTL recognition of cells latently infected with Kaposi's sarcoma-associated herpes virus. J Immunol. 2000 Aug 15;165(4):2077-83. PMID: 10925292


Jones CA, Taylor TJ, Knipe DM. Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model. Virology. 2000 Dec 5;278(1):137-50. PMID: 11112490


McNamee EE, Taylor TJ, Knipe DM. A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: effects on DNA replication and late gene expression. J Virol. 2000 Nov;74(21):10122-31. PMID: 11024141 PMCID: PMC102051 read article


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