Publications
For a complete listing of publications click here.
PiN Faculty Member - Amar Sahay, PhD
Amar Sahay, PhD Associate Professor of Psychiatry Center for Regenerative Medicine, Harvard Stem Cell Institute 185 Cambridge Street, CPZN-Room 4242 Boston, MA 02114 Tel: 617-643-4371 Fax: 617-724-2662 Email: asahay@mgh.harvard.edu Visit my lab page here. |
The incidence and complexity of mental illnesses and cognitive impairments associated with ageing and Alzheimer’s disease underscores the need to develop novel treatments. Our mission is to generate fundamental insights into the contributions of circuit- and plasticity mechanisms in the dentate gyrus (DG)-CA3 circuit in hippocampal memory processing and modulation of mood. By integrating cellular, circuit, systems and behavioral interrogation of DG-CA3 functions and adult hippocampal neurogenesis, we aspire to rejuvenate and re-engineer hippocampal circuitry to optimize circuit performance and memory processing. We predict that this strategy will edify strategies to treat PTSD, Alzheimer’s disease, social memory disorders and age-related cognitive decline.
Last Update: 9/16/2020