 | Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
 | Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
 | My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
 | lymphocyte activation and immune response |
| |
 | Vascular and Cell Biology of Inflammation and Wound Healing |
| |
 | Development of immunotherapies to target cancer. |
| |
 | T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
 | Mouse models of anti-tumor immunity |
| |
 | Molecular mechanisms of antigen presentation |
| |
 | The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
 | Function of Genes Associated with Autoimmune Disease |
| |
 | Cytotoxic Lymphocytes |
| |
 | Molecular aspects of immune recognition |
| |
 | The molecular mechanism of immunity to fungal pathogens. |
| |
 | Immune control of HIV and implications for vaccine development |
| |
 | Mechanisms of Antigen Presentation and Cellular Immunology |
| |
 | Innate Immune Signaling During Inflammation |
| |
 | The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
 | Molecular genetic, biochemical and genomic analysis of mechanisms underlying lymphocyte development, antigen receptor gene rearrangements, and oncogenic chromosomal translocations. |
| |
 | Examining the interplay of inflammation and glycosylation |
| |
 | Induction and Regulation of Antigen-specific T Cell Responses |
| |
 | Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
 | T-Lymphocyte Recognition |
| |
 | Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Development of immunotherapies to target cancer. |
| |
 | NKT and Other Immune Cell Subsets in Anti-Tumor and Anti-Viral Immunity |
| |
 | Cytotoxic T Lymphocytes |
| |
 | Pattern recognition by the B cell receptor, vaccine development |
| |
 | T-cell differentiation, tolerance and autoimmunity |
| |
 | Genetically-modified T cells as immunotherapy for cancer |
| |
 | Elucidate the molecular basis of neutrophil function in autoimmune disease and understand endothelial dependent permeability |
| |
 | Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
 | Molecular Biology of V(D)J Recombination |
| |
 | Assembly and Function of pre-B Cell-fate and B Lymphocyte Antigen Receptors |
| |
| Molecular aspects of immune recognition |
| |
 | Topics in Transplantation Biology |
| |
 | Immunology of Pregnancy, Tolerance and Multiple Sclerosis |
| |
 | Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
 | T cell Biology and Cancer Immunology |
| |
 | Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
 | Innate and adaptive immune inflammation in allergic and asthmatic models |
| |
| lymphocyte activation and immune response |
| |
 | The role of cysteinyl leukotrienes and nucleotide receptors in control of pulmonary allergic immunity |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
 | Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
 | The study of human tissue resident T cells |
| |
 | Studies on Glycosylation and Adaptive Immunity |
| |
| Molecular mechanisms of antigen presentation |
| |
 | Molecular Basis of Immunodeficiencies; Immunological and molecular basis of Atopic dermatitis |
| |
 | The Role of Cysteinyl Leukotrienes and their Receptors in Pulmonary Inflammation and Fibrosis |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
 | Biology and Function of Immunoreceptors |
| |
 | Lung host defense against inhaled pathogens, allergens and pollutants |
| |
 | Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
 | CD4+ T Cell Tolerance |
| |
 | Regulation of immune sensitization and tolerance in allergy |
| |
 | Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
| |
 | Cellular and Molecular Mechanisms of Eosinophil and Other Leukocyte Involvement in Allergic Flammation |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
 | Chronic and Inflammatory Pain, Neuronal Survival and Regeneration |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
 | Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
 | Molecular determinants of T cell phenotypes in cancer |
| |
| Examining the interplay of inflammation and glycosylation |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
 | Systems Immunology of Tolerance and Autoimmunity |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| T-Lymphocyte Recognition |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
 | Trafficking of antigen in lymph nodes |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
 | Immunoregulation |
| |
 | The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
 | Epigenomic regulation of innate immunity |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
 | Mechanisms of Autoimmune Disease |
| |
 | Immunopathogenesis and regulation of immune response in EAE |
| |
| Function of Genes Associated with Autoimmune Disease |
| |
 | Regulation of Autoimmune T Cell Responses |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Elucidate the molecular basis of neutrophil function in autoimmune disease and understand endothelial dependent permeability |
| |
 | Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
 | Tissue immunoregulation in inflammation and cancer |
| |
| Molecular Biology of V(D)J Recombination |
| |
| Molecular aspects of immune recognition |
| |
 | Rheumatic Diseases |
| |
 | Regulation of T-cell Mediated Immune Response |
| |
 | Signal Transduction, Host-Microbial Interactions and Immunology |
| |
 | We are interested in immune tolerance, particularly in settings of autoimmunity and transplantation. |
| |
| Immunology of Pregnancy, Tolerance and Multiple Sclerosis |
| |
 | Molecular Aspects of Lymphocyte Interactions |
| |
 | Immune Cell Signaling, Gene Transcription and Tissue Injury in Lupus |
| |
| Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
| |
 | Basic and Clinical Mechanisms of Autoimmunity |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| T cell Biology and Cancer Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
| Molecular determinants of T cell phenotypes in cancer |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
 | T and B Cell Lymphomas, Chromosomal Translocations and Cancer Immunology |
| |
| Development of immunotherapies to target cancer. |
| |
 | Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
 | Immune Regulation of Early Cancer Development |
| |
| Mouse models of anti-tumor immunity |
| |
 | Molecular pathogenesis of high-risk T-cell acute lymphoblastic leukemia |
| |
 | Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
 | Lipid signaling in immunity and inflammatory disease |
| |
| Genetically-modified T cells as immunotherapy for cancer |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Molecular aspects of immune recognition |
| |
 | Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| T cell Biology and Cancer Immunology |
| |
| Innate Immune Signaling During Inflammation |
| |
| lymphocyte activation and immune response |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Studies on Glycosylation and Adaptive Immunity |
| |
| Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
 | Immune Mechanisms in Cardiovascular Disease |
| |
 | Signal transduction in innate immunity |
| |
 | Cell Biology, Biochemistry, and Immunology of Leukocyte-endothelial Adhesion |
| |
| Elucidate the molecular basis of neutrophil function in autoimmune disease and understand endothelial dependent permeability |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
 | Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
 | Molecular Basis of Cell Adhesion and Migration |
| |
 | Biology and Function of Tissue-Specific Stem Cells |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Molecular pathogenesis of high-risk T-cell acute lymphoblastic leukemia |
| |
| Mechanisms of Autoimmune Disease |
| |
 | Molecular Biology of Epstein Barr Virus Infection and Transformation of B Lymphocytes |
| |
| Cytotoxic T Lymphocytes |
| |
| Signal transduction in innate immunity |
| |
| Cytotoxic Lymphocytes |
| |
| Assembly and Function of pre-B Cell-fate and B Lymphocyte Antigen Receptors |
| |
| Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
 | Engineering Immunity to dissect host-pathogen interactions |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
 | Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Mechanisms of Autoimmune Disease |
| |
| Signal transduction in innate immunity |
| |
| Cell Biology, Biochemistry, and Immunology of Leukocyte-endothelial Adhesion |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Molecular aspects of immune recognition |
| |
 | Control of Leukocyte Trafficking and the Immune Response By Chemokines and Other Cytokines |
| |
| Molecular Basis of Cell Adhesion and Migration |
| |
| Biology and Function of Tissue-Specific Stem Cells |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Engineering Immunity to dissect host-pathogen interactions |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
 | Molecular and signaling pathways regulating T cell immunity and T cell anergy |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| The study of human tissue resident T cells |
| |
| Development of immunotherapies to target cancer. |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Mouse models of anti-tumor immunity |
| |
| Molecular Basis of Immunodeficiencies; Immunological and molecular basis of Atopic dermatitis |
| |
 | Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Mechanisms of Autoimmune Disease |
| |
| Immunopathogenesis and regulation of immune response in EAE |
| |
 | Immunopathogenesis of JC virus-associated brain diseases |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Regulation of immune sensitization and tolerance in allergy |
| |
| Assembly and Function of pre-B Cell-fate and B Lymphocyte Antigen Receptors |
| |
| Topics in Transplantation Biology |
| |
| Rheumatic Diseases |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Molecular genetic, biochemical and genomic analysis of mechanisms underlying lymphocyte development, antigen receptor gene rearrangements, and oncogenic chromosomal translocations. |
| |
| Engineering Immunity to dissect host-pathogen interactions |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Immune Regulation of Early Cancer Development |
| |
 | Tumor Necrosis Factor-Alpha Gene Regulation in the Immunopathogenesis of AIDS and TB |
| |
 | Macrophage biology, macrophage activation and metabolism, immunometabolism |
| |
 | Bacteria, Immune cells and Neurodevelopment |
| |
| Epigenomic regulation of innate immunity |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
 | Toll-like Receptors and Innate Immunity |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Mechanisms of Autoimmune Disease |
| |
| Immunopathogenesis and regulation of immune response in EAE |
| |
| Regulation of Autoimmune T Cell Responses |
| |
| Immune Mechanisms in Cardiovascular Disease |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Molecular aspects of immune recognition |
| |
| Control of Leukocyte Trafficking and the Immune Response By Chemokines and Other Cytokines |
| |
| Topics in Transplantation Biology |
| |
 | Neural-Immune Interactions During Development and Disease; Synapse development |
| |
 | Innate leukocytes in acute and chronic inflammation |
| |
| Biology and Function of Tissue-Specific Stem Cells |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
 | Structural and Cellular Biology of Innate Immunity |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| Molecular genetic, biochemical and genomic analysis of mechanisms underlying lymphocyte development, antigen receptor gene rearrangements, and oncogenic chromosomal translocations. |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
| Molecular pathogenesis of high-risk T-cell acute lymphoblastic leukemia |
| |
| Cytotoxic T Lymphocytes |
| |
 | Genetic Models of Leukemogenesis |
| |
| Signal transduction in innate immunity |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
 | Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Topics in Transplantation Biology |
| |
 | Stem Cells and the Stem Cell Niche |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
 | Gene regulation in normal and leukemic stem cells |
| |
| Biology and Function of Tissue-Specific Stem Cells |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Development of immunotherapies to target cancer. |
| |
| Tumor Necrosis Factor-Alpha Gene Regulation in the Immunopathogenesis of AIDS and TB |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Molecular aspects of immune recognition |
| |
| Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
| Topics in Transplantation Biology |
| |
| Immunology of Pregnancy, Tolerance and Multiple Sclerosis |
| |
| T cell Biology and Cancer Immunology |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Molecular determinants of T cell phenotypes in cancer |
| |
| Examining the interplay of inflammation and glycosylation |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| Molecular and signaling pathways regulating T cell immunity and T cell anergy |
| |
| T-Lymphocyte Recognition |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Trafficking of antigen in lymph nodes |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Studies on Glycosylation and Adaptive Immunity |
| |
| Mouse models of anti-tumor immunity |
| |
| Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
| Epigenomic regulation of innate immunity |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Mechanisms of Autoimmune Disease |
| |
| Immunopathogenesis and regulation of immune response in EAE |
| |
| Function of Genes Associated with Autoimmune Disease |
| |
| Regulation of Autoimmune T Cell Responses |
| |
 | Bacterial pathogens and innate immunity |
| |
| Cytotoxic T Lymphocytes |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Regulation of immune sensitization and tolerance in allergy |
| |
| Molecular Biology of V(D)J Recombination |
| |
| Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Molecular aspects of immune recognition |
| |
| Topics in Transplantation Biology |
| |
| Regulation of T-cell Mediated Immune Response |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| We are interested in immune tolerance, particularly in settings of autoimmunity and transplantation. |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| Chronic and Inflammatory Pain, Neuronal Survival and Regeneration |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Engineering Immunity to dissect host-pathogen interactions |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| lymphocyte activation and immune response |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Trafficking of antigen in lymph nodes |
| |
 | Immunity to bacterial enteropathogens: modulation by host and microbial factors |
| |
| The study of human tissue resident T cells |
| |
| Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
| NKT and Other Immune Cell Subsets in Anti-Tumor and Anti-Viral Immunity |
| |
 | Interplay between the innate immune system and gut microbial communities |
| |
 | Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
 | Crystallography, electron microscopy, biochemical assays, cellular assays |
| |
| Epigenomic regulation of innate immunity |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Toll-like Receptors and Innate Immunity |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Biology and Function of Immunoreceptors |
| |
| Lung host defense against inhaled pathogens, allergens and pollutants |
| |
| Immunopathogenesis of JC virus-associated brain diseases |
| |
| Bacterial pathogens and innate immunity |
| |
| Cytotoxic T Lymphocytes |
| |
| Signal transduction in innate immunity |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
 | Biology and Chemistry of Complement Problems |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Molecular aspects of immune recognition |
| |
| Regulation of T-cell Mediated Immune Response |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
 | T-Lymphocyte Responses to Bacterial Pathogens |
| |
| Immunology of Pregnancy, Tolerance and Multiple Sclerosis |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
 | Molecular Mechanisms of Leukocyte Trafficking |
| |
| The molecular mechanism of immunity to fungal pathogens. |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Immune control of HIV and implications for vaccine development |
| |
| Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
| |
| Cellular and Molecular Mechanisms of Eosinophil and Other Leukocyte Involvement in Allergic Flammation |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Innate Immune Signaling During Inflammation |
| |
| Molecular genetic, biochemical and genomic analysis of mechanisms underlying lymphocyte development, antigen receptor gene rearrangements, and oncogenic chromosomal translocations. |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| Development of immunotherapies to target cancer. |
| |
| Molecular Basis of Immunodeficiencies; Immunological and molecular basis of Atopic dermatitis |
| |
| Immunopathogenesis of JC virus-associated brain diseases |
| |
| Cytotoxic T Lymphocytes |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| Stem Cells and the Stem Cell Niche |
| |
 | Pathogenesis of Human Retroviruses |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Immune control of HIV and implications for vaccine development |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
 | Cytotoxic Lymphocytes |
| |
| Examining the interplay of inflammation and glycosylation |
| |
| Innate and adaptive immune inflammation in allergic and asthmatic models |
| |
| lymphocyte activation and immune response |
| |
| The role of cysteinyl leukotrienes and nucleotide receptors in control of pulmonary allergic immunity |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Trafficking of antigen in lymph nodes |
| |
| Immunity to bacterial enteropathogens: modulation by host and microbial factors |
| |
| The study of human tissue resident T cells |
| |
| Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Studies on Glycosylation and Adaptive Immunity |
| |
| Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
| Lipid signaling in immunity and inflammatory disease |
| |
| Macrophage biology, macrophage activation and metabolism, immunometabolism |
| |
| The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
| Bacteria, Immune cells and Neurodevelopment |
| |
| Crystallography, electron microscopy, biochemical assays, cellular assays |
| |
| Epigenomic regulation of innate immunity |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Toll-like Receptors and Innate Immunity |
| |
| The Role of Cysteinyl Leukotrienes and their Receptors in Pulmonary Inflammation and Fibrosis |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Mechanisms of Autoimmune Disease |
| |
| Lung host defense against inhaled pathogens, allergens and pollutants |
| |
| Immunopathogenesis of JC virus-associated brain diseases |
| |
 | The cell and molecular biology of vesicular transport and a novel mechanism of innate immunity unique to the polarized epithelial cells that line mucosal surfaces |
| |
| Bacterial pathogens and innate immunity |
| |
| Immune Mechanisms in Cardiovascular Disease |
| |
| Signal transduction in innate immunity |
| |
| Cell Biology, Biochemistry, and Immunology of Leukocyte-endothelial Adhesion |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Elucidate the molecular basis of neutrophil function in autoimmune disease and understand endothelial dependent permeability |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| CD4+ T Cell Tolerance |
| |
| Biology and Chemistry of Complement Problems |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Molecular aspects of immune recognition |
| |
| Control of Leukocyte Trafficking and the Immune Response By Chemokines and Other Cytokines |
| |
| Rheumatic Diseases |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| Molecular Basis of Cell Adhesion and Migration |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| The molecular mechanism of immunity to fungal pathogens. |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Cellular and Molecular Mechanisms of Eosinophil and Other Leukocyte Involvement in Allergic Flammation |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Chronic and Inflammatory Pain, Neuronal Survival and Regeneration |
| |
| Structural and Cellular Biology of Innate Immunity |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Innate Immune Signaling During Inflammation |
| |
| Innate and adaptive immune inflammation in allergic and asthmatic models |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Trafficking of antigen in lymph nodes |
| |
| Immunity to bacterial enteropathogens: modulation by host and microbial factors |
| |
| Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
| NKT and Other Immune Cell Subsets in Anti-Tumor and Anti-Viral Immunity |
| |
| Interplay between the innate immune system and gut microbial communities |
| |
| Molecular Basis of Immunodeficiencies; Immunological and molecular basis of Atopic dermatitis |
| |
| Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| Lipid signaling in immunity and inflammatory disease |
| |
| Macrophage biology, macrophage activation and metabolism, immunometabolism |
| |
| The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
| Crystallography, electron microscopy, biochemical assays, cellular assays |
| |
| Epigenomic regulation of innate immunity |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Toll-like Receptors and Innate Immunity |
| |
| The Role of Cysteinyl Leukotrienes and their Receptors in Pulmonary Inflammation and Fibrosis |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Mechanisms of Autoimmune Disease |
| |
| Lung host defense against inhaled pathogens, allergens and pollutants |
| |
| The cell and molecular biology of vesicular transport and a novel mechanism of innate immunity unique to the polarized epithelial cells that line mucosal surfaces |
| |
| Bacterial pathogens and innate immunity |
| |
| Cytotoxic T Lymphocytes |
| |
| Signal transduction in innate immunity |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Elucidate the molecular basis of neutrophil function in autoimmune disease and understand endothelial dependent permeability |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Cytotoxic Lymphocytes |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Control of Leukocyte Trafficking and the Immune Response By Chemokines and Other Cytokines |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| Pathogenesis of Human Retroviruses |
| |
| Neural-Immune Interactions During Development and Disease; Synapse development |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
| The molecular mechanism of immunity to fungal pathogens. |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Immune control of HIV and implications for vaccine development |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| Chronic and Inflammatory Pain, Neuronal Survival and Regeneration |
| |
| Structural and Cellular Biology of Innate Immunity |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
| lymphocyte activation and immune response |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| Molecular and signaling pathways regulating T cell immunity and T cell anergy |
| |
| T-Lymphocyte Recognition |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Mouse models of anti-tumor immunity |
| |
| Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Toll-like Receptors and Innate Immunity |
| |
| Immunopathogenesis and regulation of immune response in EAE |
| |
| Function of Genes Associated with Autoimmune Disease |
| |
| Immunopathogenesis of JC virus-associated brain diseases |
| |
| Immune Mechanisms in Cardiovascular Disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Genetically-modified T cells as immunotherapy for cancer |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
| Assembly and Function of pre-B Cell-fate and B Lymphocyte Antigen Receptors |
| |
| Molecular aspects of immune recognition |
| |
| Topics in Transplantation Biology |
| |
 | Molecular Biology of Receptor Transduction in the Immune System |
| |
| Regulation of T-cell Mediated Immune Response |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| Immunology of Pregnancy, Tolerance and Multiple Sclerosis |
| |
| Immune Cell Signaling, Gene Transcription and Tissue Injury in Lupus |
| |
| Molecular Mechanisms of Leukocyte Trafficking |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| T cell Biology and Cancer Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| Engineering Immunity to dissect host-pathogen interactions |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| The role of cysteinyl leukotrienes and nucleotide receptors in control of pulmonary allergic immunity |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| Immunity to bacterial enteropathogens: modulation by host and microbial factors |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Molecular mechanisms of antigen presentation |
| |
| Interplay between the innate immune system and gut microbial communities |
| |
| Molecular Basis of Immunodeficiencies; Immunological and molecular basis of Atopic dermatitis |
| |
| Macrophage biology, macrophage activation and metabolism, immunometabolism |
| |
| The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
| Bacteria, Immune cells and Neurodevelopment |
| |
| Toll-like Receptors and Innate Immunity |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| The cell and molecular biology of vesicular transport and a novel mechanism of innate immunity unique to the polarized epithelial cells that line mucosal surfaces |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Regulation of immune sensitization and tolerance in allergy |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Immune control of HIV and implications for vaccine development |
| |
| Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Innate Immune Signaling During Inflammation |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Examining the interplay of inflammation and glycosylation |
| |
| Innate and adaptive immune inflammation in allergic and asthmatic models |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Immunity to bacterial enteropathogens: modulation by host and microbial factors |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Interplay between the innate immune system and gut microbial communities |
| |
| Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
| Lipid signaling in immunity and inflammatory disease |
| |
| The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
| Toll-like Receptors and Innate Immunity |
| |
| The Role of Cysteinyl Leukotrienes and their Receptors in Pulmonary Inflammation and Fibrosis |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Mechanisms of Autoimmune Disease |
| |
| Lung host defense against inhaled pathogens, allergens and pollutants |
| |
| Bacterial pathogens and innate immunity |
| |
| Signal transduction in innate immunity |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Molecular aspects of immune recognition |
| |
| Control of Leukocyte Trafficking and the Immune Response By Chemokines and Other Cytokines |
| |
| Regulation of T-cell Mediated Immune Response |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| Neural-Immune Interactions During Development and Disease; Synapse development |
| |
| Gene regulation in normal and leukemic stem cells |
| |
| Molecular Mechanisms of Leukocyte Trafficking |
| |
| The molecular mechanism of immunity to fungal pathogens. |
| |
| Cell Adhesion in Vascular Biology and Innate Immunity |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Immune Regulation of Early Cancer Development |
| |
| Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
| Toll-like Receptors and Innate Immunity |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Cytotoxic T Lymphocytes |
| |
| Topics in Transplantation Biology |
| |
| Immunology of Pregnancy, Tolerance and Multiple Sclerosis |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| T cell Biology and Cancer Immunology |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| T-Lymphocyte Recognition |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| NKT and Other Immune Cell Subsets in Anti-Tumor and Anti-Viral Immunity |
| |
| Mechanisms of Autoimmune Disease |
| |
| Immunopathogenesis of JC virus-associated brain diseases |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Molecular Mechanisms of Leukocyte Trafficking |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Molecular genetic, biochemical and genomic analysis of mechanisms underlying lymphocyte development, antigen receptor gene rearrangements, and oncogenic chromosomal translocations. |
| |
 | The Role of Notch Signaling in Lymphoid Neoplasia |
| |
| lymphocyte activation and immune response |
| |
| Molecular and signaling pathways regulating T cell immunity and T cell anergy |
| |
| The role of cysteinyl leukotrienes and nucleotide receptors in control of pulmonary allergic immunity |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
| Tumor Necrosis Factor-Alpha Gene Regulation in the Immunopathogenesis of AIDS and TB |
| |
| Molecular pathogenesis of high-risk T-cell acute lymphoblastic leukemia |
| |
| Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| Novel adhesion and palmitoylation mechanisms for regulating the tumor microenvironment |
| |
| Lipid signaling in immunity and inflammatory disease |
| |
| The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
| Crystallography, electron microscopy, biochemical assays, cellular assays |
| |
| Epigenomic regulation of innate immunity |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| Toll-like Receptors and Innate Immunity |
| |
| Molecular Biology of Epstein Barr Virus Infection and Transformation of B Lymphocytes |
| |
| The cell and molecular biology of vesicular transport and a novel mechanism of innate immunity unique to the polarized epithelial cells that line mucosal surfaces |
| |
| Signal transduction in innate immunity |
| |
| Elucidate the molecular basis of neutrophil function in autoimmune disease and understand endothelial dependent permeability |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| Biology and Chemistry of Complement Problems |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Molecular aspects of immune recognition |
| |
| Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
 | Chemical biology and genome biology: relating genetic variation in humans to the efficacy of small-molecule drugs |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Immune control of HIV and implications for vaccine development |
| |
| Structural and Cellular Biology of Innate Immunity |
| |
| T cell Biology and Cancer Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Innate Immune Signaling During Inflammation |
| |
| Immune surveillance of tissue-resident stem cells and cancer stem cells |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Molecular determinants of T cell phenotypes in cancer |
| |
| The Role of Notch Signaling in Lymphoid Neoplasia |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| Molecular and signaling pathways regulating T cell immunity and T cell anergy |
| |
| T-Lymphocyte Recognition |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| T and B Cell Lymphomas, Chromosomal Translocations and Cancer Immunology |
| |
| The study of human tissue resident T cells |
| |
| Development of immunotherapies to target cancer. |
| |
| Cell death, cytopenia and immunosuppression triggered by pathogen recognition |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Immune Regulation of Early Cancer Development |
| |
| Studies on Glycosylation and Adaptive Immunity |
| |
| Mouse models of anti-tumor immunity |
| |
| NKT and Other Immune Cell Subsets in Anti-Tumor and Anti-Viral Immunity |
| |
| Molecular Basis of Immunodeficiencies; Immunological and molecular basis of Atopic dermatitis |
| |
| Molecular pathogenesis of high-risk T-cell acute lymphoblastic leukemia |
| |
| Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
| Lipid signaling in immunity and inflammatory disease |
| |
 | Regulation of T Lymphocyte Activation and Differentiation |
| |
| Bacteria, Immune cells and Neurodevelopment |
| |
| Cellular ATP release ad purinergic signaling in immune cell regulation |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Mechanisms of Autoimmune Disease |
| |
| Immunopathogenesis and regulation of immune response in EAE |
| |
| Function of Genes Associated with Autoimmune Disease |
| |
| Immunopathogenesis of JC virus-associated brain diseases |
| |
| Regulation of Autoimmune T Cell Responses |
| |
| Immune Mechanisms in Cardiovascular Disease |
| |
| Cytotoxic T Lymphocytes |
| |
| Cell Biology, Biochemistry, and Immunology of Leukocyte-endothelial Adhesion |
| |
| Chemokine and lipid chemoattractants in immune cell trafficking in normal physiology and disease |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Genetically-modified T cells as immunotherapy for cancer |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Cytotoxic Lymphocytes |
| |
| CD4+ T Cell Tolerance |
| |
 | The biology of microRNAs and their dysregulation in cancers |
| |
| Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Molecular aspects of immune recognition |
| |
| Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
| Topics in Transplantation Biology |
| |
| Molecular Biology of Receptor Transduction in the Immune System |
| |
| Regulation of T-cell Mediated Immune Response |
| |
| Signal Transduction, Host-Microbial Interactions and Immunology |
| |
| We are interested in immune tolerance, particularly in settings of autoimmunity and transplantation. |
| |
| Molecular Aspects of Lymphocyte Interactions |
| |
| Immune Cell Signaling, Gene Transcription and Tissue Injury in Lupus |
| |
| Molecular Mechanisms of Leukocyte Trafficking |
| |
| Basic and Clinical Mechanisms of Autoimmunity |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| T cell Biology and Cancer Immunology |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Innate Immune Signaling During Inflammation |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Induction and Regulation of Antigen-specific T Cell Responses |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
| Molecular and signaling pathways regulating T cell immunity and T cell anergy |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Vascular and Cell Biology of Inflammation and Wound Healing |
| |
| Trafficking of antigen in lymph nodes |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| The study of human tissue resident T cells |
| |
| T cell sensitization and immunoregulation in ocular allo- and autoimmunity |
| |
| Mouse models of anti-tumor immunity |
| |
| Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Mechanisms of Autoimmune Disease |
| |
| Immunopathogenesis and regulation of immune response in EAE |
| |
| Function of Genes Associated with Autoimmune Disease |
| |
| Regulation of Autoimmune T Cell Responses |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| CD4+ T Cell Tolerance |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Regulation of immune sensitization and tolerance in allergy |
| |
| Responses mediated by innate and adaptive immune cells in cancer and other inflammatory disorders |
| |
| Molecular aspects of immune recognition |
| |
| Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
| Topics in Transplantation Biology |
| |
| Regulation of T-cell Mediated Immune Response |
| |
| We are interested in immune tolerance, particularly in settings of autoimmunity and transplantation. |
| |
| Innate leukocytes in acute and chronic inflammation |
| |
| Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Mechanisms of Antigen Presentation and Cellular Immunology |
| |
| T cell Biology and Cancer Immunology |
| |
| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
| |
| Molecular genetic, biochemical and genomic analysis of mechanisms underlying lymphocyte development, antigen receptor gene rearrangements, and oncogenic chromosomal translocations. |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| The Role of Notch Signaling in Lymphoid Neoplasia |
| |
| Systems Immunology of Tolerance and Autoimmunity |
| |
| Development and function of T cells, their subsets and distinctive markers |
| |
| Mechanisms of peripheral tolerance and their breakdown in allergic and autoimmune diseases |
| |
| Tumor Necrosis Factor-Alpha Gene Regulation in the Immunopathogenesis of AIDS and TB |
| |
| Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
| Lipid signaling in immunity and inflammatory disease |
| |
| Regulation of T Lymphocyte Activation and Differentiation |
| |
| Macrophage biology, macrophage activation and metabolism, immunometabolism |
| |
| The Role of the Transcription Factor NF-kB in Regulating Innate Inflammatory Responses |
| |
| Epigenomic regulation of innate immunity |
| |
| Toll-like Receptors and Innate Immunity |
| |
| Molecular Biology of Epstein Barr Virus Infection and Transformation of B Lymphocytes |
| |
| Immune Mechanisms in Cardiovascular Disease |
| |
| Cytotoxic T Lymphocytes |
| |
| T-cell differentiation, tolerance and autoimmunity |
| |
| Understanding the mechanisms of pathogen-sensing by the innate immune system |
| |
| The biology of microRNAs and their dysregulation in cancers |
| |
| Tissue immunoregulation in inflammation and cancer |
| |
| Gene regulation in normal and leukemic stem cells |
| |
| Lymphocyte development, antibody diversity and host: microbe interactions |
| |
| Chronic and Inflammatory Pain, Neuronal Survival and Regeneration |
| |
| Systems approaches to innate and adaptive immunity; Functional genomics of complex disease genetics |
| |
| The Human Major Histocompatibility Complex, Immune Function, and Disease |
| |
| Our lab studies unique properties of adaptive tissue specific immunity as related to tumor immune surveillance, vaccine development, and host-barrier defense. |
| |
| Engineering Immunity to dissect host-pathogen interactions |
| |
| My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. |
| |
| lymphocyte activation and immune response |
| |
| Microbial-epithelial-immune cell interactions in mucosal tissues |
| |
| T-Lymphocyte Recognition |
| |
| T and B Cell Lymphomas, Chromosomal Translocations and Cancer Immunology |
| |
 | Neuro-immune mechanisms of pain and inflammation |
| |
| The study of human tissue resident T cells |
| |
| NKT and Other Immune Cell Subsets in Anti-Tumor and Anti-Viral Immunity |
| |
| Dendritic Cells and the Initiation of Immune Reponses; Genetic Analysis using Genome-Wide Mammalian RNAi Libraries |
| |
| Our goal is to understand how functional memory T cells are formed, and why protective T cell immunity fails to develop against chronic viral infection and cancer. |
| |
| The interaction of bacteria, both commensal and pathogenic, with the immune system |
| |
| Pattern recognition by the B cell receptor, vaccine development |
| |
| Immune Cell Interactions Controlling T Cell Effector Function |
| |
| Human T cell Antigen Receptor; Human Lymphocyte Differentiation Antigens; TCR; Thymic Development; Protective Immunity; HIV-I; T cell vaccines |
| |
| Pathogenesis of Human Retroviruses |
| |
| T-Lymphocyte Responses to Bacterial Pathogens |
| |
| Immune control of HIV and implications for vaccine development |
| |
| Study of the influence of initial bacterial colonization on the development of the mucosal immune system. |
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| T cell Biology and Cancer Immunology |
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| Biology of Histocompatibility Systems in Man and Experimental Animals; Immunology of Aging |
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| Innate Immune Signaling During Inflammation |
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