BBS Faculty Member - Olivier Pourquie

Olivier Pourquie

Department of Genetics

Brigham and Women's Hospital
Building for Transformative Medicine, Room 8-8032
60 Fenwood Road
Boston, MA 02115
Tel: 617-525-4815

We are interested in the development of the vertebrate musculo-skeletal axis. Using chicken and mouse embryos as model systems, we combine developmental biology and genomic approaches to study patterning and differentiation of the precursors of muscles and vertebrae. While most of this work has been carried out in vivo, we are now developing protocols to recapitulate these early developmental processes in vitro using mouse and human embryonic or reprogrammed stem cells. We are also turning to translational approaches, using our understanding of the early development to produce cells of the muscle and vertebral lineages in vitro from pluripotent cells to study human diseases of the musculo-skeletal axis and for cell therapy approaches.

Last Update: 12/7/2016


For a complete listing of publications click here.



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