BBS Faculty Member - Richard Lee

Richard Lee

Department of Stem Cell and Regenerative Biology

Harvard Stem Cell Institute
Sherman Fairchild Building, Room 159
7 Divinity Avenue
Cambridge, MA 02138
Tel: 617-496-5394
Lab Members: 7 postdoctoral fellows, 2 graduate students
Visit my lab page here.

My research laboratory is a part of the Brigham Regenerative Medicine Center, a research program I direct. My laboratory’s approach is to understand important problems at a molecular level, design solutions in the laboratory and then demonstrate the effectiveness of these solutions in vivo. We are particularly interested in using lessons from developmental biology to design solutions for regenerative medicine. Ongoing projects in the laboratory include studies of cardiac regeneration, diabetes, aging and heart failure. I enjoy my role as a mentor for graduate students, research fellows and physician scientists who wish to pursue questions in molecular medicine.

Last Update: 7/27/2016


For a complete listing of publications click here.



Patwari P, Emilsson V, Schadt EE, Chutkow WA, Lee S, Marsili A, Zhang Y, Dobrin R, Cohen DE, Larsen PR, Zavacki AM, Fong LG, Young SG, Lee RT. The Arrestin Domain Containing 3 (ARRDC3) Protein Regulates Body Mass and Energy Expenditure. Cell Metabolism 2011;14:1-13.

Steinhauser ML, Bailey A, Senyo SE, Guillermier C, Perlstein TS, Gould AP, Lee RT, Lechene CP. Quantitating subcellular metabolism with multi-isotope imaging mass spectrometry.
Nature 2012;481:516-9.

Senyo SE, Steinhauser ML, Pizzimenti CL, Yang VK, Cai L, Wang M, Wu TD, Guerquin-Kern JL, Lechene CP, Lee RT. Mammalian Heart Renewal by Preexisting Cardiomyocytes.
Nature 2012; 2012; 493:433-6.

Growth Differentiation Factor 11 is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy. Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall’Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ*, Lee RT*.
Cell 2013;153:828-39.. *Drs. Lee and Wagers co-supervised the project.

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