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LATEST NEWS
Lab pioneers new approach to RNAi screen data-sharing
August 10, 2008 - The recent explosion of genetic screens fostered by a process called RNA interference (RNAi) imbues scientists with new responsibilities when it comes to sharing information. One HMS lab has risen to the challenge. continue reading >
Researchers halt spread of HIV with RNAi
August 7, 2008 - Using a novel method to deliver small molecules called siRNAs into T cells, researchers dramatically suppressed HIV in the first-ever animal model that mirrors progression of the disease in humans. The siRNAs knocked down three key genes and kept the infection from spreading in mice containing human immune cells infected with the virus. continue reading >
XDR-TB can be cured, study finds
August 7, 2008 - Extensively drug-resistant tuberculosis (XDR-TB) no longer has to be a death sentence. A recent study shows XDR-TB can be cured in HIV-negative patients through individualized outpatient treatment, even in countries with limited resources and a heavy burden of TB. continue reading >
Being a control freak aids dividing cells
July 28, 2008 - A dividing cell tags more than 14,000 different sites on its proteins with phosphate, a molecule that typically serves as a signal for a variety of biological processes. This preponderance of signals—more than twice the number identified by past studies—suggests that the cell may become a control freak during the division process, regulating each of its parts, no matter how obscure. continue
reading >
Biology enters “The Matrix” through new computer
language
July 22, 2008 - A new computer language
for modeling biological phenomenon can “think” like cells and
molecular mechanisms think, thereby simulating the dynamics of biological
phenomenon. Through incorporating basic principles of engineering,
the new language, called Little b, surpasses current biological
modeling software in that it goes beyond simply representing
biological information. It allows biologists to create programs
that can reason about biological knowledge and thereby help
overcome the barrier of complexity. continue
reading >
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