At a time when the world faces numerous public health crises, scientists at the New England Primate Research Center (NEPRC) are extending the boundaries of research, making discoveries that will lead to better diagnosis, prevention, and treatment of human disease.

Historically, nonhuman primate research has played a key role in the development of new medical treatment and prevention strategies. Biological similarities between humans and nonhuman primates provide unique opportunities to advance the control of infectious disease, cancer, and neurological disorders. Through research on nonhuman primates, the incidence and devastating consequences of poliomyelitis, smallpox, measles, and hepatitis B have declined dramatically.

In the 21st century, we face formidable new challenges. Newly emerging viruses, drug-resistant pathogens, aggressive cancers, drug addiction, and neurological disorders have frustrated effective treatment and are testing the mettle of clinicians and scientists.

Investigators in the Center's Divisions of Comparative Pathology, Immunology, Microbiology, Tumor Virology, and Primate Medicine are studying the mechanisms of immune destruction in AIDS, the development of AIDS vaccines, and the pathogenesis of viral-induced cancers. Their colleagues in the Divisions of Behavioral Biology and Neurochemistry are breaking new ground in our understanding and treatment of drug addiction, neuropsychiatric disorders, and Parkinson's disease.

Multidisciplinary collaboration has been the cornerstone of NEPRC's success. Working closely with biomedical researchers from around the world, scientists at NEPRC have made significant contributions to the development and practical use of nonhuman primate models of human disease.

NEPRC scientists have developed the most widely used animal model of AIDS and were the first to demonstrate that vaccine protection against AIDS is possible. The Center's earlier research on the addictive properties of nicotine helped set the stage for the landmark Surgeon General's report on smoking and health. Recent development of novel agents for brain imaging is paving the way for improved diagnosis and treatment of Parkinson's disease.

On this site you will learn more about the Center's diverse research programs and its exciting opportunities for collaboration and training.