Our senior faculty, all of whom hold academic appointments at Harvard Medical School, serve on numerous advisory boards for governmental agencies, private foundations, and biotechnology organizations. Their scientific accomplishments have been recognized by national awards and leadership positions in professional societies and scientific journals. The Center also maintains active affiliations with over 200 scientists nationwide through its Collaborative and Affiliated Scientist Programs.

RONALD C. DESROSIERS, Ph.D., Professor of Microbiology and Molecular Genetics, Harvard Medical School, is Director of NERPRC and Chair of the Division of Microbiology. His research focuses on simian retroviruses and herpesviruses, molecular mechanisms of viral pathogenicity, and AIDS vaccine development.

ROGER D. SPEALMAN, Ph.D., Professor of Psychobiology in the Department of Psychiatry, Harvard Medical School, is Associate Director for Scientific Affairs and Chair of the Division of Behavioral Biology. His research focuses on the biological basis and treatment of drug addiction, neuropsychiatric disorders, and neurodegenerative disease.

BERTHA K. MADRAS, Ph.D., Professor of Psychobiology in the Department of Psychiatry, Harvard Medical School, is Chair of the Division of Neurochemistry. Her research focuses on diagnostic imaging and medications development for, and neurochemical mechanisms of, dopamine-related brain disorders, including Parkinson's disease, cocaine addiction, and attention deficit-hyperactivity disorder.

KEITH G. MANSFIELD, D.V.M., D.A.C.V.P., Associate Director for Resource and Collaborative Affairs and Assistant Professor of Pathology, Harvard Medical School, is Chair of the Division of Primate Resources. His research focuses on opportunistic infections and intestinal dysfunction in simian AIDS.

R. PAUL JOHNSON, M.D., Associate Professor of Medicine, Harvard Medical School, is Chair of the Division of Immunology. His research focuses on T lymphocyte responses to HIV and SIV, protective immunity in the SIV-rhesus macaque model, and development of gene therapy for AIDS.

SHAWN P. O'NEIL, D.V.M., Ph.D., Assistant Professor of Pathology, Harvard Medical School, is Chair of the Division of Comparative Pathology. His research focuses on the pathogenesis and treatment of HIV and SIV encephalitis, the mechanisms involved in the mucosal transmission of HIV and SIV, and the protective adaptations that prevent the natural reservoir hosts of SIV from developing simian AIDS.

JAMES K. ROWLETT, Ph.D., Assistant Professor of Psychobiology in the Department of Psychiatry, Harvard Medical School, supervises the Behavioral Pharmacology Laboratory of the Division of Behavioral Biology. His research focuses on the behavioral and biological basis of drug addiction and the development of pharmacotherapies to treat addiction and anxiety disorders.

MICHAEL R. FARZAN, Ph.D., is Assistant Professor in the Department of Microbiology and Molecular Genetics, Harvard Medical School. The Farzan laboratory is interested in (1) the role of the coreceptors in HIV-1 and SIV entry (1) the process by which other enveloped viruses, including the SARS coronavirus , filoviruses, and flaviviruses. enter their respective target cells, (2) the development and use of mass spectrometry as a tool for analyzing antibody and T-cell responses to HIV-1 and SIV.

AMITINDER KAUR, M.D. is Assistant Professor of Medicine, Harvard Medical School in the Division of Immunology. Her research focuses on the immunology of cytomegalovirus and other herpesvirus infections in simian AIDS, mechanisms of protection against AIDS in natural hosts of the simian immunodeficiency virus, and immune responses induced by AIDS vaccines.

WEI-DONG YAO, Ph.D. is Assistant Professor of Psychiatry, in the Department of Psychiatry, Harvard Medical School. His research focuses on the molecular and synaptic mechanisms of drug addiction, neuropsychiatric, and neurodegenerative disorders.

GREGORY M. MILLER, Ph.D., Assistant Professor in the Department of Psychiatry, Harvard Medical School, is Acting Chair of the Division of Neuroscience. His research focuses on natural modeling of human polygenetic disorders in rhesus monkeys through the identification of functional parallels in the neurogenetics, neurobiology and immunobiology shared with humans.

DAVID T. EVANS, Ph.D., is Assistant Professor in the Department of Microbiology and Molecular Genetics, Harvard Medical School. His research focuses on novel AIDS vaccine approaches, viral pathogenesis and mechanisms of immune evasion using simian immunodeficiency virus (SIV) infection of rhesus macaques as an animal model. SIV causes AIDS in infected macaques with a course of disease progression that closely resembles HIV infection of humans. SIV infection of macaques is therefore a valuable model for AIDS vaccine development and for studies of lentiviral pathogenesis.

WELKIN JOHNSON , Ph.D., is Assistant Professor in the Department of Microbiology and Molecular Genetics, Harvard Medical School. His research interests include: mechanisms of antibody-mediated neutralization, and resistance to antibody-mediated neutralization, of AIDS viruses SIV and HIV; the role of intracellular immunity factors in restricting viral replication; the impact of host genetic factors on the outcome of viral infections.

SUSAN V. WESTMORELAND , V.M.D., D.A.C.V.P., Assistant Professor of Pathology, Harvard Medical School, is Chief of Service Pathology in the Division of Comparative Pathology. Her research focuses on HIV/SIV neuropathogenesis, Pediatric encephalitis, and mechanisms of neuronal dysfunction and repair.

ANGELA A. L. CARVILLE , B.V.M.S, Chief of Primate Medicine. Her research interests are opportunistic infections and cardiac abnormalities in the Simian Immunodeficiency virus infected rhesus macaque model.