2024

Russell MD, Abdelhamid Ahmed AH, Feng Z, Shonka DC Jr, Karcioglu AS, Iwata AJ, Kyriazidis N, Siddiqui SH, Athni TS, Park JC, Wirth LJ, Zafereo ME, Randolph GW. Recovery of Recurrent Laryngeal Nerve Function With Neoadjuvant Treatment: Neural Characterization. Laryngoscope. 2024 Jan 24. doi: 10.1002/lary.31304. Epub ahead of print. PMID: 38264976.

Russell M, Gild ML, Wirth LJ, Robinson B, Karcioglu AS, Iwata A, Athni TS, Abdelhamid Ahmed AH, Randolph GW. Neoadjuvant therapy to improve resectability of advanced thyroid cancer: A real-world experience. Head Neck. 2024 Mar 15. doi: 10.1002/hed.27735. Epub ahead of print. PMID: 38488238.

Sumpio BJ, Dallas A, Berger AG, Li Z, Wang E, Mezghani I, Contreras M, Theocharidis G, Ilves H, Hammond PT, Johnston B, Veves A. Use of therapeutic RNAs to accelerate wound healing in diabetic rabbit wounds. Adv Wound Care (New Rochelle). 2024 Jan 6. doi: 10.1089/wound.2023.0056. Epub ahead of print. PMID: 38183631.

Eweje F, Walsh ML, Ahmad K, Ibrahim V, Alrefai A, Chen J, Chaikof EL. Protein-based nanoparticles for therapeutic nucleic acid delivery. Biomaterials. 2024 Mar;305:122464. doi: 10.1016/j.biomaterials.2023.122464. Epub 2024 Jan 2. PMID: 38181574.

Wamhoff EC, Ronsard L, Feldman J, Knappe GA, Hauser BM, Romanov A, Case JB, Sanapala S, Lam EC, Denis KJS, Boucau J, Barczak AK, Balazs AB, Diamond MS, Schmidt AG, Lingwood D, Bathe M. Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds. Nat Commun. 2024 Jan 30;15(1):795. doi: 10.1038/s41467-024-44869-0. PMID: 38291019; PMCID: PMC10828404.

Hauser BM, Sangesland M, Lam EC, St Denis KJ, Sheehan ML, Vu ML, Cheng AH, Sordilla S, Lamson DT, Almawi AW, Balazs AB, Lingwood D, Schmidt AG. Heterologous Sarbecovirus Receptor Binding Domains as Scaffolds for SARS-CoV-2 Receptor Binding Motif Presentation. ACS Infect Dis. 2024 Jan 28. doi: 10.1021/acsinfecdis.3c00483. Epub ahead of print. PMID: 38281136.

Gupta S, Hoffman SE, Mehta NH, Hauser B, Altshuler M, Bernstock JD, Smith TR, Arnaout O, Laws ER. Elevated risk of recurrence and retreatment for silent pituitary adenomas. Pituitary. 2024 Feb 12. doi: 10.1007/s11102-024-01382-3. Epub ahead of print. PMID: 38345720.

Gupta S, Hoffman SE, Mehta NH, Hauser B, Altshuler M, Bernstock JD, Smith TR, Arnaout O, Laws ER. Elevated risk of recurrence and retreatment for silent pituitary adenomas. Pituitary. 2024 Feb 12. doi: 10.1007/s11102-024-01382-3. Epub ahead of print. PMID: 38345720.

Zeng K, Brewster R, Kang JB, Tkachenko E, Brooks E, Bhatt AS, Fodor AA, Andermann TM. Acute Steroid-Refractory Gastrointestinal Graft-Versus-Host Disease Is Not Associated With Significant Differences in Gut Taxonomic Composition Compared to Steroid-Sensitive Gastrointestinal Graft-Versus-Host Disease Immediately Before Onset of Disease. Transplant Cell Ther. 2024 Feb;30(2):237.e1-237.e9. doi: 10.1016/j.jtct.2023.11.006. Epub 2023 Nov 7. PMID: 37944820; PMCID: PMC10872415.

Wehrli M, Guinn S, Birocchi F, Kuo A, Sun Y, Larson RC, Almazan AJ, Scarfò I, Bouffard AA, Bailey SR, Anekal PV, Montero Lopis P, Nieman LT, Song Y, Xu KH, Berger TR, Kann MC, Leick MB, Silva H, Salas-Benito D, Kienka T, Grauwet K, Armstrong TD, Zhang R, Zhu Q, Fu J, Schmidts A, Korell F, Jan M, Choi BD, Liss AS, Boland GM, Ting DT, Burkhart RA, Jenkins RW, Zheng L, Jaffee EM, Zimmerman JW, Maus MV. Mesothelin CAR T-cells secreting anti-FAP/anti-CD3 molecules efficiently target pancreatic adenocarcinoma and its stroma. Clin Cancer Res. 2024 Feb 23. doi: 10.1158/1078-0432.CCR-23-3841. Epub ahead of print. PMID: 38393682.

Kincaid JWR, Rimmington D, Tadross JA, Cimino I, Zvetkova I, Kaser A, Richards P, Patel S, O'Rahilly S, Coll AP. The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15. Sci Rep. 2024 Jan 22;14(1):1899. doi: 10.1038/s41598-024-51866-2. PMID: 38253650; PMCID: PMC10803367.

Kline MC, Kissler SM, Whittles LK, Barnett ML, Grad YH. Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States. Clin Infect Dis. 2024 Feb 19:ciae083. doi: 10.1093/cid/ciae083. Epub ahead of print. PMID: 38373257.

Lagattuta KA, Park HL, Rumker L, Ishigaki K, Nathan A, Raychaudhuri S. The genetic basis of autoimmunity seen through the lens of T cell functional traits. Nat Commun. 2024 Feb 8;15(1):1204. doi: 10.1038/s41467-024-45170-w. PMID: 38331990; PMCID: PMC10853555.

Lai J, Demirbas D, Kim J, Jeffries AM, Tolles A, Park J, Chittenden TW, Buckley PG, Yu TW, Lodato MA, Lee EA. ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia. Cell Rep. 2024 Jan 23;43(1):113622. doi: 10.1016/j.celrep.2023.113622. Epub 2023 Dec 29. PMID: 38159274; PMCID: PMC10908398.

Lawton RI, Sabatini BL, Hochbaum DR. Longevity, demographic characteristics, and socio-economic status are linked to triiodothyronine levels in the general population. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2308652121. doi: 10.1073/pnas.2308652121. Epub 2024 Jan 4. PMID: 38175866; PMCID: PMC10786306.

Lawton RI, Stanford FC. The Role of Racism in Childhood Obesity. Curr Obes Rep. 2024 Jan 3. doi: 10.1007/s13679-023-00538-9. Epub ahead of print. PMID: 38172479.

Levine ZC, Sene A, Mkandawire W, Deme AB, Ndiaye T, Sy M, Gaye A, Diedhiou Y, Mbaye AM, Ndiaye IM, Gomis J, Ndiop M, Sene D, Faye Paye M, MacInnis BL, Schaffner SF, Park DJ, Badiane AS, Colubri A, Ndiaye M, Sy N, Sabeti PC, Ndiaye D, Siddle KJ. Investigating the etiologies of non-malarial febrile illness in Senegal using metagenomic sequencing. Nat Commun. 2024 Jan 25;15(1):747. doi: 10.1038/s41467-024-44800-7. PMID: 38272885; PMCID: PMC10810818.

Saberi SA, Moore S, Li S, Mather RV, Daniels MB, Shahani A, Barreveld A, Griswold T, McGuire P, Connery HS. Systemized approach to equipping medical students with naloxone: a student-driven initiative to combat the opioid crisis. BMC Med Educ. 2024 Mar 6;24(1):241. doi: 10.1186/s12909-024-05221-8. PMID: 38448949; PMCID: PMC10916177.

Laane CLE, Dijkmans AL, Messinger CJ, Wijffels MME, Bhashyam AR, Chen NC. Cause of Extensor Pollicis Longus Ruptures After Distal Radius Fracture Fixation Using a Volar Plate. Hand (N Y). 2024 Feb 29:15589447241233763. doi: 10.1177/15589447241233763. Epub ahead of print. PMID: 38420781.

Zorrilla-Vaca A, Grant MC, Law M, Messinger CJ, Pelosi P, Varelmann D. Dexmedetomidine improves pulmonary outcomes in thoracic surgery under one-lung ventilation: A meta-analysis. J Clin Anesth. 2024 May;93:111345. doi: 10.1016/j.jclinane.2023.111345. Epub 2023 Nov 20. PMID: 37988813.

Li Y, Choudhary MC, Regan J, Boucau J, Nathan A, Speidel T, Liew MY, Edelstein GE, Kawano Y, Uddin R, Deo R, Marino C, Getz MA, Reynolds Z, Barry M, Gilbert RF, Tien D, Sagar S, Vyas TD, Flynn JP, Hammond SP, Novack LA, Choi B, Cernadas M, Wallace ZS, Sparks JA, Vyas JM, Seaman MS, Gaiha GD, Siedner MJ, Barczak AK, Lemieux JE, Li JZ. SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency. Sci Transl Med. 2024 Jan 24;16(731):eadk1599. doi: 10.1126/scitranslmed.adk1599. Epub 2024 Jan 24. PMID: 38266109.

Welch NL, Zhu M, Hua C, Weller J, Mirhashemi ME, Nguyen TG, Mantena S, Bauer MR, Shaw BM, Ackerman CM, Thakku SG, Tse MW, Kehe J, Uwera MM, Eversley JS, Bielwaski DA, McGrath G, Braidt J, Johnson J, Cerrato F, Moreno GK, Krasilnikova LA, Petros BA, Gionet GL, King E, Huard RC, Jalbert SK, Cleary ML, Fitzgerald NA, Gabriel SB, Gallagher GR, Smole SC, Madoff LC, Brown CM, Keller MW, Wilson MM, Kirby MK, Barnes JR, Park DJ, Siddle KJ, Happi CT, Hung DT, Springer M, MacInnis BL, Lemieux JE, Rosenberg E, Branda JA, Blainey PC, Sabeti PC, Myhrvold C. Author Correction: Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants. Nat Med. 2024 Jan;30(1):307. doi: 10.1038/s41591-023-02684-y. Erratum for: Nat Med. 2022 May;28(5):1083-1094. PMID: 37946059; PMCID: PMC10803257.

Zhou I*, Plana D*, Palmer AC. Tumor-Specific Activity of Precision Medicines in the NCI-MATCH Trial. Clin Cancer Res. 2024 Feb 16;30(4):786-792. doi: 10.1158/1078-0432.CCR-23-0983. PMID: 38109210; PMCID: PMC10922532.

Lagattuta KA, Park HL, Rumker L, Ishigaki K, Nathan A, Raychaudhuri S. The genetic basis of autoimmunity seen through the lens of T cell functional traits. Nat Commun. 2024 Feb 8;15(1):1204. doi: 10.1038/s41467-024-45170-w. PMID: 38331990; PMCID: PMC10853555.

2023

Castrillon C, Simoni L, van den Broek T, van der Poel C, Akama-Garren EH, Ma M, Carroll MC. Complex subsets but redundant clonality after B cells egress from spontaneous germinal centers. Elife. 2023 Jun 21;12:e81012. doi: 10.7554/eLife.81012. PMID: 37341394; PMCID: PMC10351918.

Akama-Garren EH, Miller P, Carroll TM, Tellier M, Sutendra G, Buti L, Zaborowska J, Goldin RD, Slee E, Szele FG, Murphy S, Lu X. Regulation of immunological tolerance by the p53-inhibitor iASPP. Cell Death Dis. 2023 Feb 6;14(2):84. doi: 10.1038/s41419-023-05567-9. PMID: 36746936; PMCID: PMC9902554.

Miller P, Akama-Garren EH, Owen RP, Demetriou C, Carroll TM, Slee E, Al Moussawi K, Ellis M, Goldin R, O'Neill E, Lu X. p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer. Cell Death Differ. 2023 Jun 3. doi: 10.1038/s41418-023-01168-3. Epub ahead of print. PMID: 37270580.

Akula SK, Chen AY, Neil JE, Shao DD, Mo A, Hylton NK, DiTroia S, Ganesh VS, Smith RS, O'Kane K, Yeh RC, Marciano JH, Kirkham S, Kenny CJ, Song JHT, Al Saffar M, Millan F, Harris DJ, Murphy AV, Klemp KC, Braddock SR, Brand H, Wong I, Talkowski ME, O'Donnell-Luria A, Lai A, Hill RS, Mochida GH, Doan RN, Barkovich AJ, Yang E, Amrom D, Andermann E, Poduri A, Walsh CA; Polymicrogyria Genetics Research Network. Exome Sequencing and the Identification of New Genes and Shared Mechanisms in Polymicrogyria. JAMA Neurol. 2023 Sep 1;80(9):980-988. doi: 10.1001/jamaneurol.2023.2363. PMID: 37486637; PMCID: PMC10366952.

Dias CM, Issac B, Sun L, Lukowicz A, Talukdar M, Akula SK, Miller MB, Walsh K, Rockowitz S, Walsh CA. Glial dysregulation in the human brain in fragile X-associated tremor/ataxia syndrome. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2300052120. doi: 10.1073/pnas.2300052120. Epub 2023 May 30. PMID: 37252957; PMCID: PMC10265985.

Akula SK, Marciano JH, Lim Y, Exposito-Alonso D, Hylton NK, Hwang GH, Neil JE, Dominado N, Bunton-Stasyshyn RK, Song JHT, Talukdar M, Schmid A, Teboul L, Mo A, Shin T, Finander B, Beck SG, Yeh RC, Otani A, Qian X, DeGennaro EM, Alkuraya FS, Maddirevula S, Cascino GD, Giannini C; Undiagnosed Diseases Network; Burrage LC, Rosenfield JA, Ketkar S, Clark GD, Bacino C, Lewis RA, Segal RA, Bazan JF, Smith KA, Golden JA, Cho G, Walsh CA. TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2209964120. doi: 10.1073/pnas.2209964120. Epub 2023 Jan 20. PMID: 36669111; PMCID: PMC9942790.

Allbritton-King JD, García-Cardeña G. Endothelial cell dysfunction in cardiac disease: driver or consequence? Front Cell Dev Biol. 2023 Oct 25;11:1278166. doi: 10.3389/fcell.2023.1278166. PMID: 37965580; PMCID: PMC10642230.

Allbritton-King JD, Maity J, Patel A, Colbert RA, Navid F, Bhattacharyya T. VEGF Secretion Drives Bone Formation in Classical MAP2K1+ Melorheostosis. J Bone Miner Res. 2023 Sep 22. doi: 10.1002/jbmr.4915. Epub ahead of print. PMID: 37737377.

Patel A, Allbritton-King JD, Paul S, Bhattacharyya T. Bone health is improving over time: data from Framingham cohorts. Arch Osteoporos. 2023 Sep 16;18(1):119. doi: 10.1007/s11657-023-01327-6. PMID: 37715080.

Athni TS, Barmettler S. Hypogammaglobulinemia, late-onset neutropenia, and infections following rituximab. Ann Allergy Asthma Immunol. 2023 Jan 24:S1081-1206(23)00042-X. doi: 10.1016/j.anai.2023.01.018. Epub ahead of print. PMID: 36706910.

Hauser BM, Gupta S, Athni TS, Segar DJ, Uppaluri R, Arnaout O. Endoscopic endonasal transclival approach for a ventral brainstem epidermoid cyst: illustrative case. J Neurosurg Case Lessons. 2023 Mar 27;5(13):CASE22538. doi: 10.3171/CASE22538. PMID: 37014021.

Chiang S, Yu SE, Athni TS, Bergmark RW, Maxfield AZ, Roditi RE, Buchheit KM, Lundberg M, Mitchell MB, Lee SE. Not just snot: local inflammatory profiles in patients with aspirin-exacerbated respiratory disease differ from patients with aspirin-tolerant chronic rhinosinusitis. Int Forum Allergy Rhinol. 2023 Jun 16. doi: 10.1002/alr.23216. Epub ahead of print. PMID: 37325975.

Yu SE, Athni TS, Mitchell MB, Zhou X, Chiang S, Lee SE. The Impact of Ambient and Wildfire Air Pollution on Rhinosinusitis and Olfactory Dysfunction. Curr Allergy Asthma Rep. 2023 Dec;23(12):665-673. doi: 10.1007/s11882-023-01110-0. Epub 2023 Dec 4. PMID: 38047993.

Talasila S, Teichner EM, Subtirelu RC, Xiang DH, Ayubcha C, Werner T, Alavi A, Revheim ME. The Role of FDG-PET in the Evaluation of Hidradenitis Suppurativa: A Systematic Review. J Clin Med. 2023 Aug 24;12(17):5491. doi: 10.3390/jcm12175491. PMID: 37685556; PMCID: PMC10488012.

Hameed R, Bahadur AR, Singh SB, Sher J, Todua M, Moradi LM, Bastakoti S, Arslan M, Ajmal H, Lee GY, Ayubcha C, Werner TJ, Alavi A, Revheim ME. Neurological and Psychiatric Manifestations of Long COVID-19 and Their [18F]FDG PET Findings: A Review. Diagnostics (Basel). 2023 Jul 12;13(14):2353. doi: 10.3390/diagnostics13142353. PMID: 37510097; PMCID: PMC10378471.

Ayubcha C, Singh SB, Patel KH, Rahmim A, Hasan J, Liu L, Werner T, Alavi A. Machine learning in the positron emission tomography imaging of Alzheimer's disease. Nucl Med Commun. 2023 Sep 1;44(9):751-766. doi: 10.1097/MNM.0000000000001723. Epub 2023 Jul 3. PMID: 37395538.

Ayubcha C, Amanullah A, Patel KH, Teichner E, Gokhale S, Marquez-Valenzuela U, Werner TJ, Alavi A. Stroke and molecular imaging: a focus on FDG-PET. Am J Nucl Med Mol Imaging. 2023 Apr 25;13(2):51-63. PMID: 37214267; PMCID: PMC10193198.

Mamidi RS, Ayubcha C, Rigney G, Kirschner J, Gerke O, Werner TJ, Tebas P, Alavi A, Revheim ME. A prospective 18 F-fluorodeoxyglucose positron emission tomography/computed tomography study of the neurometabolic effects in cocaine use and HIV infection. AIDS. 2023 May 1;37(6):905-912. doi: 10.1097/QAD.0000000000003485. Epub 2023 Jan 19. PMID: 36727840; PMCID: PMC10090338.

Deiss-Yehiely E, Cárcamo-Oyarce G, Berger AG, Ribbeck K, Hammond PT. pH-Responsive, Charge-Reversing Layer-by-Layer Nanoparticle Surfaces Enhance Biofilm Penetration and Eradication. ACS Biomater Sci Eng. 2023 Aug 14;9(8):4794-4804. doi: 10.1021/acsbiomaterials.3c00481. Epub 2023 Jun 30. PMID: 37390118.

Berger AG, Deiss-Yehiely E, Vo C, McCoy MG, Almofty S, Feinberg MW, Hammond PT. Electrostatically assembled wound dressings deliver pro-angiogenic anti-miRs preferentially to endothelial cells. Biomaterials. 2023 Sep;300:122188. doi: 10.1016/j.biomaterials.2023.122188. Epub 2023 Jun 12. PMID: 37329684; PMCID: PMC10424785.

Lee DH, Jin Q, Shi N, Wang F, Bever AM, Liang L, Hu FB, Song M, Zeleznik OA, Zhang X, Joshi A, Wu K, Jeon JY, Meyerhardt JA, Chan AT, Eliassen AH, Clish C, Clinton SK, Giovannucci EL, Li J, Tabung FK. The metabolic potential of inflammatory and insulinaemic dietary patterns and risk of type 2 diabetes. Diabetologia. 2024 Jan;67(1):88-101. doi: 10.1007/s00125-023-06021-3. Epub 2023 Oct 11. PMID: 37816982.

Lee DH, Jin Q, Shi N, Wang F, Bever AM, Li J, Liang L, Hu FB, Song M, Zeleznik OA, Zhang X, Joshi A, Wu K, Jeon JY, Meyerhardt JA, Chan AT, Eliassen AH, Clish CB, Clinton SK, Giovannucci EL, Tabung FK. Dietary Inflammatory and Insulinemic Potentials, Plasma Metabolome and Risk of Colorectal Cancer. Metabolites. 2023 Jun 12;13(6):744. doi: 10.3390/metabo13060744. PMID: 37367904; PMCID: PMC10304271.

Bever AM, Song M. Early-life exposures and adulthood cancer risk: A life course perspective. J Natl Cancer Inst. 2023 Jan 10;115(1):4-7. doi: 10.1093/jnci/djac193. PMID: 36214630; PMCID: PMC9830471.

Tang A, Ertel KA, Keen R, Beyer L, Eckert N, Mita C, Pintro K, Okuzono SS, Yazawa A, Slopen N. Parent-child separation and cardiometabolic outcomes and risk factors in adulthood: A systematic review. Psychoneuroendocrinology. 2023 Jun;152:106084. doi: 10.1016/j.psyneuen.2023.106084. Epub 2023 Mar 15. PMID: 36996574; PMCID: PMC10565792.

Ni P, Mayo H, Fernández-Del Castillo C, Elamin S, Brown DR, Mino-Kenudson M, Krishnan K, Casey B, Lafaro K, Lennon AM, Afghani E, Hernandez-Barco YG. Impact of preoperative endoscopic procedures on adverse event rates after surgical resection for main-duct and mixed-type intraductal papillary mucinous neoplasms (IPMNs). Pancreatology. 2023 Nov 14:S1424-3903(23)01844-6. doi: 10.1016/j.pan.2023.11.007. Epub ahead of print. PMID: 37981524.

Mielko Z, Zhang Y, Sahay H, Liu Y, Schaich MA, Schnable B, Morrison AM, Burdinski D, Adar S, Pufall M, Van Houten B, Gordân R, Afek A. UV irradiation remodels the specificity landscape of transcription factors. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2217422120. doi: 10.1073/pnas.2217422120. Epub 2023 Mar 8. PMID: 36888663; PMCID: PMC10089200.

Wuo MG, Dugan AE, Halim M, Hauser BM, Feldman J, Caradonna TM, Zhang S, Pepi LE, Atyeo C, Fischinger S, Alter G, Garcia-Beltran WF, Azadi P, Hung D, Schmidt AG, Kiessling LL. Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2. ACS Cent Sci. 2023 May 10;9(5):947-956. doi: 10.1021/acscentsci.2c01471. PMID: 37252360; PMCID: PMC10214521.

Nanishi E, Borriello F, Seo HS, O'Meara TR, McGrath ME, Saito Y, Chen J, Diray-Arce J, Song K, Xu AZ, Barman S, Menon M, Dong D, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Baden LR, Ernst RK, Dillen C, Yu J, Chang A, Hilgers L, Platenburg PP, Dhe-Paganon S, Barouch DH, Ozonoff A, Zanoni I, Frieman MB, Dowling DJ, Levy O. Publisher Correction: Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ Vaccines. 2023 Mar 3;8(1):30. doi: 10.1038/s41541-023-00634-w. Erratum for: NPJ Vaccines. 2023 Feb 14;8(1):18. PMID: 36869134; PMCID: PMC9982769.

Nanishi E, Borriello F, Seo HS, O'Meara TR, McGrath ME, Saito Y, Chen J, Diray-Arce J, Song K, Xu AZ, Barman S, Menon M, Dong D, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Baden LR, Ernst RK, Dillen C, Yu J, Chang A, Hilgers L, Platenburg PP, Dhe-Paganon S, Barouch DH, Ozonoff A, Zanoni I, Frieman MB, Dowling DJ, Levy O. Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice. NPJ Vaccines. 2023 Feb 14;8(1):18. doi: 10.1038/s41541-023-00610-4. Erratum in: NPJ Vaccines. 2023 Mar 3;8(1):30. PMID: 36788219; PMCID: PMC9927065.

Yang L, Caradonna TM, Schmidt AG, Chakraborty AK. Mechanisms that promote the evolution of cross-reactive antibodies upon vaccination with designed influenza immunogens. Cell Rep. 2023 Mar 28;42(3):112160. doi: 10.1016/j.celrep.2023.112160. Epub 2023 Mar 2. PMID: 36867533; PMCID: PMC10184763.

Zhang H, Nabel CS, Li D, O'Connor RÍ, Crosby CR, Chang SM, Hao Y, Stanley R, Sahu S, Levin DS, Chen T, Tang S, Huang HY, Meynardie M, Stephens J, Sherman F, Chafitz A, Costelloe N, Rodrigues DA, Fogarty H, Kiernan MG, Cronin F, Papadopoulos E, Ploszaj M, Weerasekara V, Deng J, Kiely P, Bardeesy N, Vander Heiden MG, Chonghaile TN, Dowling CM, Wong KK. Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC. J Thorac Oncol. 2023 Jul;18(7):882-895. doi: 10.1016/j.jtho.2023.03.014. Epub 2023 Mar 22. PMID: 36958689; PMCID: PMC10332301.

Chen L, McWilliams JM. Chief Residency-More Than Just Teaching and Scheduling-Reply. JAMA Intern Med. 2023 Sep 1;183(9):1031-1032. doi: 10.1001/jamainternmed.2023.2676. PMID: 37399031.

Chen L, McWilliams JM. Performance on Patient Experience Measures of Former Chief Medical Residents as Physician Exemplars Chosen by the Profession. JAMA Intern Med. 2023 Apr 1;183(4):350-359. doi: 10.1001/jamainternmed.2023.0025. PMID: 36848122; PMCID: PMC9972239.

Gordon S, Whitman A, Sugar S, Chen L, Peters C, De Lew N, Sommers BD. Medicaid After Pregnancy: State-Level Implications of Extending Postpartum Coverage (2023 Update). (Issue Brief No. HP2023-10). Office of the Assistant Secretary for Planning and Evaluation, U.S. Department of Health and Human Services. April 2023. https://aspe.hhs.gov/reports/extending-medicaid-postpartum-coverage-2023-update

Chen MZ, Tolchin DW. A stakeholder-engaged approach to disability in medical education. Med Educ. 2023 Nov;57(11):1139. doi: 10.1111/medu.15227. Epub 2023 Sep 14. PMID: 37709344.

Cheng YC, Perpetuini P, Murcko L, Hirayama M, Morgan K, Marincola M, Bonfante EA, Bergamo ETP, Ewers R. Fiber-reinforced composite full-arch prosthetic reconstructions supported by three standard, short or extra-short implants: a two-center retrospective study. Clin Oral Investig. 2023 Aug;27(8):4191-4203. doi: 10.1007/s00784-023-05035-w. Epub 2023 May 4. PMID: 37140762.

Ramanan D, Chowdhary K, Candéias SM, Sassone-Corsi M, Gelineau A, Mathis D, Benoist C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2311566120. doi: 10.1073/pnas.2311566120. Epub 2023 Dec 8. PMID: 38064511; PMCID: PMC10723124.

Leon J, Chowdhary K, Zhang W, Ramirez RN, André I, Hur S, Mathis D, Benoist C. Mutations from patients with IPEX ported to mice reveal different patterns of FoxP3 and Treg dysfunction. Cell Rep. 2023 Aug 29;42(8):113018. doi: 10.1016/j.celrep.2023.113018. Epub 2023 Aug 21. PMID: 37605532; PMCID: PMC10565790.

Ramanan D, Pratama A, Zhu Y, Venezia O, Sassone-Corsi M, Chowdhary K, Galván-Peña S, Sefik E, Brown C, Gélineau A, Mathis D, Benoist C. Regulatory T cells in the face of the intestinal microbiota. Nat Rev Immunol. 2023 Nov;23(11):749-762. doi: 10.1038/s41577-023-00890-w. Epub 2023 Jun 14. PMID: 37316560.

Chowdhary K, Benoist C. A variegated model of transcription factor function in the immune system. Trends Immunol. 2023 Jul;44(7):530-541. doi: 10.1016/j.it.2023.05.001. Epub 2023 May 29. PMID: 37258360; PMCID: PMC10332489.

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Blitz SE, Hoffman SE, Stippler M, Huntoon K. Differential Time-To-Promotion Trajectories Among Female and Male Neurosurgeons Contribute to Gender Disparities in Academic Rank Achievement. World Neurosurg. 2023 Dec 21;183:157-163. doi: 10.1016/j.wneu.2023.12.081. Epub ahead of print. PMID: 38135149.

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Kamath T, Macosko EZ. Insights into Neurodegeneration in Parkinson's Disease from Single-Cell and Spatial Genomics. Mov Disord. 2023 Apr;38(4):518-525. doi: 10.1002/mds.29374. Epub 2023 Mar 7. PMID: 36881930.

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Maury EA, Walsh CA, Kahle KT. Neurosurgery elucidates somatic mutations. Science. 2023 Dec 22;382(6677):1360-1362. doi: 10.1126/science.adj2244. Epub 2023 Dec 21. PMID: 38127765.

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McNamara SL, Seo BR, Freedman BR, Roloson EB, Alvarez JT, O'Neill CT, Vandenburgh HH, Walsh CJ, Mooney DJ. Anti-inflammatory therapy enables robot-actuated regeneration of aged muscle. Sci Robot. 2023 Mar 22;8(76):eadd9369. doi: 10.1126/scirobotics.add9369. Epub 2023 Mar 22. PMID: 36947599; PMCID: PMC10328427.

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Ehwi RJ, Oti-Sarpong K, Burgess G, Lenhard J, Meng E. Modular Homes as a New Form of Accommodation to Tackle Homelessness: A Case Study From Cambridge, England. Hum Ecol Interdiscip J. 2023;51(2):323-336. doi: 10.1007/s10745-023-00404-1. Epub 2023 Apr 12. PMID: 37122817; PMCID: PMC10090745.

Lenhard J, Margetts M, Meng E. Of not passing: homelessness, addiction, mental health and care during COVID-19. Med Humanit. 2023 Mar;49(1):55-63. doi: 10.1136/medhum-2021-012367. Epub 2022 Jul 12. PMID: 35820777; PMCID: PMC9985758.

Messinger CJ, Madenci AL, Wanis KN. Addressing the longitudinal components of surgical treatments. Eur J Epidemiol. 2023 Oct;38(10):1019-1023. doi: 10.1007/s10654-023-01045-w. Epub 2023 Sep 4. PMID: 37667140.

Michelson DA, Zuo C, Verzi M, Benoist C, Mathis D. Hnf4 activates mimetic-cell enhancers to recapitulate gut and liver development within the thymus. J Exp Med. 2023 Oct 2;220(10):e20230461. doi: 10.1084/jem.20230461. Epub 2023 Jul 3. PMID: 37399024; PMCID: PMC10318407.

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Pinho-Ribeiro FA, Deng L, Neel DV, Erdogan O, Basu H, Yang D, Choi S, Walker AJ, Carneiro-Nascimento S, He K, Wu G, Stevens B, Doran KS, Levy D, Chiu IM. Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature. 2023 Mar 1. doi: 10.1038/s41586-023-05753-x. Epub ahead of print. PMID: 36859544.

Neel DV, Ma C, Collins NB, Hornick JL, Demetri GD, Shulman DS. Derivation and validation of a risk classification tree for patients with synovial sarcoma. Cancer Med. 2023 Jan;12(1):170-178. doi: 10.1002/cam4.4909. Epub 2022 Jun 7. PMID: 35670308; PMCID: PMC9844650.

Nety SP, Altae-Tran H, Kannan S, Demircioglu FE, Faure G, Hirano S, Mears K, Zhang Y, Macrae RK, Zhang F. The Transposon-Encoded Protein TnpB Processes Its Own mRNA into ωRNA for Guided Nuclease Activity. CRISPR J. 2023 Jun;6(3):232-242. doi: 10.1089/crispr.2023.0015. PubMed PMID: 37272862; PubMed Central PMCID: PMC10278001.

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Ramappa S, Anderson A, Jung J, Chu R, Cummings KK, Patterson G, Okada NJ, Green SA. An Observed Assessment of Sensory Responsivity in Autism Spectrum Disorders: Associations with Diagnosis, Age, and Parent Report. J Autism Dev Disord. 2023 Oct;53(10):3860-3872. doi: 10.1007/s10803-022-05653-5. Epub 2022 Aug 4. PMID: 35927515; PMCID: PMC9898461.

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Overhage L, Hailu R, Busch AB, Mehrotra A, Michelson KA, Huskamp HA. Trends in Acute Care Use for Mental Health Conditions Among Youth During the COVID-19 Pandemic. JAMA Psychiatry. 2023 Sep 1;80(9):924-932. doi: 10.1001/jamapsychiatry.2023.2195. PMID: 37436733; PMCID: PMC10339224.

Pany MJ, McWilliams JM. Physician-Peer Relationships and Patient Experiences With Specialist Care. JAMA Intern Med. 2023 Feb 1;183(2):124-132. doi: 10.1001/jamainternmed.2022.6007. PMID: 36595288; PMCID: PMC9857606.

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Phadnis VV, Snider J, Varadharajan V, Ramachandiran I, Deik AA, Lai ZW, Kunchok T, Eaton EN, Sebastiany C, Lyakisheva A, Vaccaro KD, Allen J, Yao Z, Wong V, Geng B, Weiskopf K, Clish CB, Brown JM, Stagljar I, Weinberg RA, Henry WS. MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis. Cell Rep. 2023 Sep 26;42(9):113023. doi: 10.1016/j.celrep.2023.113023. Epub 2023 Sep 8. PMID: 37691145.

Pierson L, Verguet S. When should global health actors prioritise more uncertain interventions? Lancet Glob Health. 2023 Apr;11(4):e615-e622. doi: 10.1016/S2214-109X(23)00055-4. PMID: 36925181; PMCID: PMC10060118.

Pierson L, Tsai B. Misaligned AI constitutes a growing public health threat. BMJ. 2023 Jun 12;381:1340. doi: 10.1136/bmj.p1340. PMID: 37308217.

Hwangbo H, Patterson SC, Dai A, Plana D, Palmer AC. Additivity predicts the efficacy of most approved combination therapies for advanced cancer. Nat Cancer. 2023 Dec;4(12):1693-1704. doi: 10.1038/s43018-023-00667-z. Epub 2023 Nov 16. PMID: 37974028.

Kazmierski M, Welch M, Kim S, McIntosh C, Rey-McIntyre K, Huang SH, Patel T, Tadic T, Milosevic M, Liu FF, Ryczkowski A, Kazmierska J, Ye Z, Plana D, Aerts HJWL, Kann BH, Bratman SV, Hope AJ, Haibe-Kains B. Multi-institutional Prognostic Modeling in Head and Neck Cancer: Evaluating Impact and Generalizability of Deep Learning and Radiomics. Cancer Res Commun. 2023 Jun 29;3(6):1140-1151. doi: 10.1158/2767-9764.CRC-22-0152. PMID: 37397861; PMCID: PMC10309070.

Peterson JS, Plana D, Bitterman DS, Johnson SB, Aerts HJWL, Kann BH. Growth in eligibility criteria content and failure to accrue among National Cancer Institute (NCI)-affiliated clinical trials. Cancer Med. 2023 Feb;12(4):4715-4724. doi: 10.1002/cam4.5276. Epub 2022 Nov 18. PMID: 36398619; PMCID: PMC9972031.

Fox DB, Ebright RY, Hong X, Russell HC, Guo H, LaSalle TJ, Wittner BS, Poux N, Vuille JA, Toner M, Hacohen N, Boland GM, Sen DR, Sullivan RJ, Maheswaran S, Haber DA. Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade. NPJ Precis Oncol. 2023 Mar 2;7(1):25. doi: 10.1038/s41698-023-00362-3. PMID: 36864091; PMCID: PMC9981575.

Kwolek DG, Gerstberger S, Tait S, Qiu JM. Ovarian, Uterine, and Vulvovaginal Cancers: Screening, Treatment Overview, and Prognosis. Med Clin North Am. 2023 Mar;107(2):329-355. doi: 10.1016/j.mcna.2022.10.016. Epub 2023 Jan 2. PMID: 36759101.

Rao A, Kim J, Kamineni M, Pang M, Lie W, Dreyer KJ, Succi MD. Evaluating GPT as an Adjunct for Radiologic Decision Making: GPT-4 Versus GPT-3.5 in a Breast Imaging Pilot. J Am Coll Radiol. 2023 Jun 21:S1546-1440(23)00394-0. doi: 10.1016/j.jacr.2023.05.003. Epub ahead of print. PMID: 37356806

Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Luo Y, Sakaue S, Raychaudhuri S. Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution. Nat Genet. 2023 Dec;55(12):2255-2268. doi: 10.1038/s41588-023-01586-6. Epub 2023 Nov 30. PMID: 38036787; PMCID: PMC10787945.

Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter JC, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Cell Metab. 2023 May 2;35(5):887-905.e11. doi: 10.1016/j.cmet.2023.03.018. Epub 2023 Apr 18. PMID: 37075753.

Sedlak JC, Yilmaz ÖH, Roper J. Metabolism and Colorectal Cancer. Annu Rev Pathol. 2023 Jan 24;18:467-492. doi: 10.1146/annurev-pathmechdis-031521-041113. Epub 2022 Nov 2. PMID: 36323004; PMCID: PMC9877174.

Fourman MS, Siraj L, Duvall J, Ramsey DC, De La Garza Ramos R, Hadzipasic M, Connolly I, Williamson T, Shankar GM, Schoenfeld A, Yassari R, Massaad E, Shin JH. Can We Use Artificial Intelligence Cluster Analysis to Identify Patients with Metastatic Breast Cancer to the Spine at Highest Risk of Postoperative Adverse Events? World Neurosurg. 2023 Feb 18:S1878-8750(23)00213-9. doi: 10.1016/j.wneu.2023.02.064. Epub ahead of print. PMID: 36805503.

Duvall JB, Massaad E, Siraj L, Kiapour A, Connolly I, Hadzipasic M, Elsamadicy AA, Williamson T, Shankar GM, Schoenfeld AJ, Fourman MS, Shin JH. Assessment of Spinal Metastases Surgery Risk Stratification Tools in Breast Cancer by Molecular Subtype. Neurosurgery. 2023 Jan 1;92(1):83-91. doi: 10.1227/neu.0000000000002180. Epub 2022 Oct 28. PMID: 36305664; PMCID: PMC10158884.

Dias CM, Issac B, Sun L, Lukowicz A, Talukdar M, Akula SK, Miller MB, Walsh K, Rockowitz S, Walsh CA. Glial dysregulation in the human brain in fragile X-associated tremor/ataxia syndrome. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2300052120. doi: 10.1073/pnas.2300052120. Epub 2023 May 30. PMID: 37252957; PMCID: PMC10265985.

Akula SK, Marciano JH, Lim Y, Exposito-Alonso D, Hylton NK, Hwang GH, Neil JE, Dominado N, Bunton-Stasyshyn RK, Song JHT, Talukdar M, Schmid A, Teboul L, Mo A, Shin T, Finander B, Beck SG, Yeh RC, Otani A, Qian X, DeGennaro EM, Alkuraya FS, Maddirevula S, Cascino GD, Giannini C; Undiagnosed Diseases Network; Burrage LC, Rosenfield JA, Ketkar S, Clark GD, Bacino C, Lewis RA, Segal RA, Bazan JF, Smith KA, Golden JA, Cho G, Walsh CA. TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2209964120. doi: 10.1073/pnas.2209964120. Epub 2023 Jan 20. PMID: 36669111; PMCID: PMC9942790.

Toker JS, Wilson JH, Dahal A, Oshotse CO, Williams DL, Kamineni M, Cha J. Wearing the White Coat on the Web: An M1 Perspective. JCO Oncol Pract. 2023 Sep;19(9):828-829. doi: 10.1200/OP.23.00163. Epub 2023 Jun 19. PMID: 37335968.

Toker J, Iorgulescu JB, Ling AL, Villa GR, Gadet JAMA, Parida L, Getz G, Wu CJ, Reardon DA, Chiocca EA, Mineo M. Clinical Importance of the lncRNA NEAT1 in Cancer Patients Treated with Immune Checkpoint Inhibitors. Clin Cancer Res. 2023 Jun 13;29(12):2226-2238. doi: 10.1158/1078-0432.CCR-22-3714. PMID: 37053197; PMCID: PMC10330151.

Agénor M, Unger ES, McConnell MA, Brown C, Rosenthal MB, Haneuse S, Bowen DJ, Austin SB. Affordable Care Act state Medicaid expansion and human papillomavirus vaccination among adolescent and young adult US women: A national study. Health Serv Res. 2023 Jan 12. doi: 10.1111/1475-6773.14133. Epub ahead of print. PMID: 36632778.

Vigue D, Rooney M, Nowakowski-Sims E, Woods S. Trauma informed weight lifting: considerations for coaches, trainers and gym environments. Front Psychol. 2023 Jul 20;14:1224594. doi: 10.3389/fpsyg.2023.1224594. PMID: 37546487; PMCID: PMC10400004.

Eva Nowakowski-Sims, Mariah Rooney, Dana Vigue, Savannah Woods, A grounded theory of weight lifting as a healing strategy for trauma, Mental Health and Physical Activity, Volume 25, 2023, 100521, ISSN 1755-2966,
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Rosa-Caldwell ME, Mortreux M, Wadhwa A, Kaiser UB, Sung DM, Bouxsein ML, Rutkove SB. Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats. J Appl Physiol (1985). 2023 Jun 1;134(6):1438-1449. doi: 10.1152/japplphysiol.00023.2023. Epub 2023 Apr 27. PMID: 37102698; PMCID: PMC10228673.

Hanč P, Messou MA, Wang Y, von Andrian UH. Control of myeloid cell functions by nociceptors. Front Immunol. 2023 Mar 17;14:1127571. doi: 10.3389/fimmu.2023.1127571. PMID: 37006298; PMCID: PMC10064072.

Hanč P, Gonzalez RJ, Mazo IB, Wang Y, Lambert T, Ortiz G, Miller EW, von Andrian UH. Multimodal control of dendritic cell functions by nociceptors. Science. 2023 Mar 31;379(6639):eabm5658. doi: 10.1126/science.abm5658. Epub 2023 Mar 31. PMID: 36996219.

Weiner DJ*, Nadig A*, Jagadeesh KA, Dey KK, Neale BM, Robinson EB, Karczewski KJ, O'Connor LJ. Polygenic architecture of rare coding variation across 394,783 exomes. Nature. 2023 Feb 8. doi: 10.1038/s41586-022-05684-z. Epub ahead of print. PMID: 36755099.

Hanna BS, Yaghi OK, Langston PK, Mathis D. The potential for Treg-enhancing therapies in tissue, in particular skeletal muscle, regeneration. Clin Exp Immunol. 2023 Mar 16;211(2):138-148. doi: 10.1093/cei/uxac076. PMID: 35972909; PMCID: PMC10019136.

Gordon KS, Kyung T, Perez CR, Holec PV, Ramos A, Zhang AQ, Agarwal Y, Liu Y, Koch CE, Starchenko A, Joughin BA, Lauffenburger DA, Irvine DJ, Hemann MT, Birnbaum ME. Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains. Nat Biomed Eng. 2023 Apr;7(4):599-602. doi: 10.1038/s41551-023-01006-4. Erratum for: Nat Biomed Eng. 2022 Jul;6(7):855-866. PMID: 36737667.

2022

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Akama-Garren EH, Carroll MC. Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion. J Immunol. 2022 May 15;208(10):2403-2424. doi: 10.4049/jimmunol.2200098. Epub 2022 Apr 27. PMID: 35477687; PMCID: PMC9254690.

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Allbritton-King JD, Elrod JK, Rosenberg PS, Bhattacharyya T. Reverse engineering the FRAX algorithm: Clinical insights and systematic analysis of fracture risk. Bone. 2022 Jun;159:116376. doi: 10.1016/j.bone.2022.116376. Epub 2022 Feb 28. PMID: 35240349; PMCID: PMC9035136.

Anderson JR, Li J, Springer TA, Brown A. Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange. Blood. 2022 Sep 22;140(12):1419-1430. doi: 10.1182/blood.2022016467. PMID: 35776905.

Borja AJ, Saini J, Raynor WY, Ayubcha C, Werner TJ, Alavi A, Revheim ME, Nagaraj C. Role of Molecular Imaging with PET/MR Imaging in the Diagnosis and Management of Brain Tumors. PET Clin. 2022 Jul;17(3):431-451. doi: 10.1016/j.cpet.2022.03.002. Epub 2022 May 31. PMID: 35662494.

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Howard MT, Wang S, Berger AG, Martin JR, Jalili-Firoozinezhad S, Padera RF, Hammond PT. Sustained release of BMP-2 using self-assembled layer-by-layer film-coated implants enhances bone regeneration over burst release. Biomaterials. 2022 Sep;288:121721. doi: 10.1016/j.biomaterials.2022.121721. Epub 2022 Aug 10. PMID: 35981926.

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Bever AM, Song M. Early life exposures and adulthood cancer risk: a life course perspective. J Natl Cancer Inst. 2022 Oct 10:djac193. doi: 10.1093/jnci/djac193. Epub ahead of print. PMID: 36214630.

Cote DJ, Bever AM, Chiu YH, Sandoval-Insausti H, Smith-Warner SA, Chavarro JE, Stampfer MJ. Pesticide Residue Intake From Fruit and Vegetable Consumption and Risk of Glioma. Am J Epidemiol. 2022 Mar 24;191(5):825-833. doi: 10.1093/aje/kwac007. PMID: 35029641; PMCID: PMC9430420.

Bever AM, Hang D, He X, Joshi AD, Ding M, Wu K, Chan AT, Giovannucci EL, Song M. Genetic Obesity Variants and Risk of Conventional Adenomas and Serrated Polyps. Dig Dis Sci. 2022 Aug;67(8):4078-4085. doi: 10.1007/s10620-021-07193-x. Epub 2021 Aug 17. PMID: 34403030; PMCID: PMC9255950.

Yirga A, Beyer L, Patt E, Tolchin D. Including disability in the equity and diversity conversation: Honing advocacy skills through curriculum development. Journal of the HMS Academy 2(3). March 2022.

Hauser BM, Sangesland M, St Denis KJ, Lam EC, Case JB, Windsor IW, Feldman J, Caradonna TM, Kannegieter T, Diamond MS, Balazs AB, Lingwood D, Schmidt AG. Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. Cell Rep. 2022 Mar 22;38(12):110561. doi: 10.1016/j.celrep.2022.110561. Epub 2022 Mar 7. PMID: 35303475; PMCID: PMC8898741.

Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, Prevost-Reilly A, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Sage PT, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Sci Transl Med. 2022 Jan 26;14(629):eabj5305. doi: 10.1126/scitranslmed.abj5305. Epub 2022 Jan 26. PMID: 34783582.

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Branham DK, Finegold K, Chen L, Sorbero M, Euller R, Elliott MN, Sommers BD. Trends in Missing Race and Ethnicity Information After Imputation in HealthCare.gov Marketplace Enrollment Data, 2015-2021. JAMA Netw Open. 2022 Jun 1;5(6):e2216715. doi: 10.1001/jamanetworkopen.2022.16715. PMID: 35687340; PMCID: PMC9187953.

Rokicki S, Steenland MW, Geiger CK, Gourevitch RA, Chen L, Martin MW, Cohen JL. Trends in postpartum mental health care before and during COVID-19. Health Serv Res. 2022 Aug 19:10.1111/1475-6773.14051. doi: 10.1111/1475-6773.14051. Epub ahead of print. PMID: 36059179; PMCID: PMC9539265.

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Chang SM, Vander Heiden MG. Inhibiting GLUTtony in cancer. Cell Chem Biol. 2022 Mar 17;29(3):353-355. doi: 10.1016/j.chembiol.2022.03.004. PMID: 35303439.

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Ramirez RN, Chowdhary K, Leon J, Mathis D, Benoist C. FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression. Sci Immunol. 2022 Jan 14;7(67):eabj9836. doi: 10.1126/sciimmunol.abj9836. Epub 2022 Jan 14. PMID: 35030035; PMCID: PMC9059705.

Leon J, Michelson DA, Olejnik J, Chowdhary K, Oh HS, Hume AJ, Galván-Peña S, Zhu Y, Chen F, Vijaykumar B, Yang L, Crestani E, Yonker LM, Knipe DM, Mühlberger E, Benoist C. A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2116853118. doi: 10.1073/pnas.2116853118. PMID: 34969849; PMCID: PMC8740714.

Clark LE, Clark SA, Lin C, Liu J, Coscia A, Nabel KG, Yang P, Neel DV, Lee H, Brusic V, Stryapunina I, Plante KS, Ahmed AA, Catteruccia F, Young-Pearse TL, Chiu IM, Llopis PM, Weaver SC, Abraham J. VLDLR and ApoER2 are receptors for multiple alphaviruses. Nature. 2022 Feb;602(7897):475-480. doi: 10.1038/s41586-021-04326-0. Epub 2021 Dec 20. PMID: 34929721; PMCID: PMC8808280.

Nabel KG, Clark SA, Shankar S, Pan J, Clark LE, Yang P, Coscia A, McKay LGA, Varnum HH, Brusic V, Tolan NV, Zhou G, Desjardins M, Turbett SE, Kanjilal S, Sherman AC, Dighe A, LaRocque RC, Ryan ET, Tylek C, Cohen-Solal JF, Darcy AT, Tavella D, Clabbers A, Fan Y, Griffiths A, Correia IR, Seagal J, Baden LR, Charles RC, Abraham J. Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science. 2022 Jan 21;375(6578):eabl6251. doi: 10.1126/science.abl6251. Epub 2022 Jan 21. PMID: 34855508.

Cote DJ, Bever AM, Chiu YH, Sandoval-Insausti H, Smith-Warner SA, Chavarro JE, Stampfer MJ. Pesticide Residue Intake From Fruit and Vegetable Consumption and Risk of Glioma. Am J Epidemiol. 2022 Mar 24;191(5):825-833. doi: 10.1093/aje/kwac007. PMID: 35029641; PMCID: PMC9430420.

Dannenberg PH, Kang J, Martino N, Kashiparekh A, Forward S, Wu J, Liapis AC, Wang J, Yun SH. Laser particle activated cell sorting in microfluidics. Lab Chip. 2022 Jun 14;22(12):2343-2351. doi: 10.1039/d2lc00235c. PMID: 35621381; PMCID: PMC9195882.

Miller AB, Davis SH, Mulder LA, Winer JP, Issa OM, Cardeli E, Ellis BH. Leveraging community-based mental health services to reduce inequities for children and families living in United States who have experienced migration-related trauma. Psychol Trauma. 2022 Oct 27. doi: 10.1037/tra0001392. Epub ahead of print. PMID: 36301293.

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Drosu N, Giovannoni G, Lechner-Scott J, Hawkes C, Yeh A, Levy M. EBV as the "gluten of MS" hypothesis provides a rationale for trialing antiviral therapies. Mult Scler Relat Disord. 2022 Aug;64:104007. doi: 10.1016/j.msard.2022.104007. Epub 2022 Jul 1. PMID: 35803161.

Chamzas* C., F. Eweje*, L. E. Kavraki, and E. L. Chaikof. 2022. Human Health and Equity in an Age of Robotics and Intelligent Machines. NAM Perspectives. Commentary, National Academy of Medicine, Washington, DC. https://doi.org/10.31478/202203b.

Whitman MC, Gilette NM, Bell JL, Kim SA, Tischfield M, Engle EC. TWIST1, a gene associated with Saethre-Chotzen syndrome, regulates extraocular muscle organization in mouse. Dev Biol. 2022 Oct;490:126-133. doi: 10.1016/j.ydbio.2022.07.010. Epub 2022 Aug 6. PMID: 35944701.

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Hoffman SE*, Hauser BM*, Zaki MM, Gupta S, Chua M, Bernstock JD, Khawaja AM, Smith TR, Zaidi HA. Spinal level and cord involvement in the prediction of sepsis development after vertebral fracture repair for traumatic spinal injury. J Neurosurg Spine. 2022 Feb 4:1-7. doi: 10.3171/2021.12.SPINE21423. Epub ahead of print. PMID: 35120317.

Amraei R, Xia C, Olejnik J, White MR, Napoleon MA, Lotfollahzadeh S, Hauser BM, Schmidt AG, Chitalia V, Mühlberger E, Costello CE, Rahimi N. Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2113874119. doi: 10.1073/pnas.2113874119. PMID: 35078919.

Garcia-Beltran WF, St Denis KJ, Hoelzemer A, Lam EC, Nitido AD, Sheehan ML, Berrios C, Ofoman O, Chang CC, Hauser BM, Feldman J, Roederer AL, Gregory DJ, Poznansky MC, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant. Cell. 2022 Feb 3;185(3):457-466.e4. doi: 10.1016/j.cell.2021.12.033. Epub 2022 Jan 6. PMID: 34995482; PMCID: PMC8733787.

Hauser BM, Sangesland M, St Denis KJ, Lam EC, Case JB, Windsor IW, Feldman J, Caradonna TM, Kannegieter T, Diamond MS, Balazs AB, Lingwood D, Schmidt AG. Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. Cell Rep. 2022 Mar 22;38(12):110561. doi: 10.1016/j.celrep.2022.110561. Epub 2022 Mar 7. PMID: 35303475; PMCID: PMC8898741.

Tan CS, Collier AY, Yu J, Liu J, Chandrashekar A, McMahan K, Jacob-Dolan C, He X, Roy V, Hauser BM, Munt JE, Mallory ML, Mattocks M, Powers JM, Meganck RM, Rowe M, Hemond R, Bondzie EA, Jaegle KH, Baric RS, Schmidt AG, Alter G, Le Gars M, Sadoff J, Barouch DH. Durability of Heterologous and Homologous COVID-19 Vaccine Boosts. JAMA Netw Open. 2022 Aug 1;5(8):e2226335. doi: 10.1001/jamanetworkopen.2022.26335. PMID: 35947380; PMCID: PMC9366542.

Rosenberg A, Jayaram A, Still M, Hauser B, Dworkin M, Faktor K, Petroze R. Global Surgery Opportunities for General Surgery Residents: Are We Making Progress? J Surg Res. 2022 Nov;279:436-441. doi: 10.1016/j.jss.2022.06.043. Epub 2022 Jul 13. PMID: 35841812.

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Hauser BM, McNulty J, Zaki MM, Gupta S, Cote DJ, Bernstock JD, Lu Y, Chi JH, Groff MW, Khawaja AM, Smith TR, Zaidi HA. Predictors of thoracic and lumbar spine injuries in patients with TBI: A nationwide analysis. Injury. 2022 Mar;53(3):1087-1093. doi: 10.1016/j.injury.2021.09.060. Epub 2021 Oct 2. PMID: 34625238; PMCID: PMC8863622.

Hauser BM, Sangesland M, Lam EC, Feldman J, Balazs AB, Lingwood D, Schmidt AG. Humoral responses to the SARS-CoV-2 spike and receptor binding domain in context of pre-existing immunity confer broad sarbecovirus neutralization. Front Immunol. 2022 Aug 4;13:902260. doi: 10.3389/fimmu.2022.902260. PMID: 35990628; PMCID: PMC9386501.

Tas JMJ, Koo JH, Lin YC, Xie Z, Steichen JM, Jackson AM, Hauser BM, Wang X, Cottrell CA, Torres JL, Warner JE, Kirsch KH, Weldon SR, Groschel B, Nogal B, Ozorowski G, Bangaru S, Phelps N, Adachi Y, Eskandarzadeh S, Kubitz M, Burton DR, Lingwood D, Schmidt AG, Nair U, Ward AB, Schief WR, Batista FD. Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses. Immunity. 2022 Oct 11;55(10):1856-1871.e6. doi: 10.1016/j.immuni.2022.07.020. Epub 2022 Aug 4. PMID: 35987201; PMCID: PMC9350677.

Hauser BM, Feldman J, Sangesland M, Ronsard L, St Denis KJ, Sheehan ML, Cao Y, Boucau J, Windsor IW, Cheng AH, Vu ML, Cardoso MR, Kannegieter T, Balazs AB, Lingwood D, Garcia-Beltran WF, Schmidt AG. Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design. Cell Rep Med. 2022 Dec 20;3(12):100834. doi: 10.1016/j.xcrm.2022.100834. Epub 2022 Nov 15. PMID: 36423634; PMCID: PMC9663748.

Rosu ME, Lexmond P, Bestebroer TM, Hauser BM, Smith DJ, Herfst S, Fouchier RAM. Substitutions near the HA receptor binding site explain the origin and major antigenic change of the B/Victoria and B/Yamagata lineages. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2211616119. doi: 10.1073/pnas.2211616119. Epub 2022 Oct 10. PMID: 36215486; PMCID: PMC9586307.

Stark N, Hayirli T, Bhanja A, Kerrissey M, Hardy J, Peabody CR. Unprecedented Training: Experience of Residents During the COVID-19 Pandemic. Ann Emerg Med. 2022 May;79(5):488-494. doi: 10.1016/j.annemergmed.2022.01.022. Epub 2022 Jan 24. PMID: 35277294; PMCID: PMC8784436.

Alidina S, Sydlowski MM, Ahearn O, Andualem BG, Barash D, Bari S, Barringer E, Bekele A, Beyene AD, Burssa DG, Derbew M, Drown L, Gulilat D, Gultie TK, Hayirli TC, Meara JG, Staffa SJ, Workineh SE, Zanial N, Zeleke ZB, Mengistu AE, Ashengo TA. Implementing surgical mentorship in a resource-constrained context: a mixed methods assessment of the experiences of mentees, mentors, and leaders, and lessons learned. BMC Med Educ. 2022 Aug 31;22(1):653. doi: 10.1186/s12909-022-03691-2. PMID: 36045356; PMCID: PMC9434847.

Kerrissey MJ, Hayirli TC, Bhanja A, Stark N, Hardy J, Peabody CR. How psychological safety and feeling heard relate to burnout and adaptation amid uncertainty. Health Care Manage Rev. 2022 Oct-Dec 01;47(4):308-316. doi: 10.1097/HMR.0000000000000338. Epub 2022 Feb 17. PMID: 35135989; PMCID: PMC9422764.

Bhanja A, Hayirli T, Stark N, Hardy J, Peabody CR, Kerrissey M. Team and leadership factors and their relationship to burnout in emergency medicine during COVID-19: A 3-wave cross-sectional study. J Am Coll Emerg Physicians Open. 2022 Jun 30;3(4):e12761. doi: 10.1002/emp2.12761. PMID: 35782348; PMCID: PMC9245504.

Hayirli TC, Warinner CB. Hospital Characteristics Associated with the Availability of Interventional Radiology Facilities and Services. Radiology. 2022 Dec 6:221189. doi: 10.1148/radiol.221189. Epub ahead of print. PMID: 36472535.

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Guo JA, Alshalalfa M, Kim DY, Hoffman HI, Shiau C, Su J, Hwang WL, Mahal BA. DNA repair and immune checkpoint blockade response. Cancer Genet. 2022 Jun;264-265:1-4. doi: 10.1016/j.cancergen.2022.02.007. Epub 2022 Feb 24. PMID: 35245846.

Bernstock JD, Hoffman SE, Kappel AD, Valdes PA, Essayed W, Klinger NV, Kang KD, Totsch SK, Olsen HE, Schlappi CW, Filipski K, Gessler FA, Baird L, Filbin MG, Hashizume R, Becher OJ, Friedman GK. Immunotherapy approaches for the treatment of diffuse midline gliomas. Oncoimmunology. 2022 Sep 26;11(1):2124058. doi: 10.1080/2162402X.2022.2124058. PMID: 36185807; PMCID: PMC9519005

Hoffman SE, Vega RA, Stippler M. Teaching through the screen: a toolbox for creating a virtual neurosurgical subinternship program. Neurosurg Focus. 2022 Aug;53(2):E7. doi: 10.3171/2022.5.FOCUS22171. PMID: 35916089.

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Xiao T, Langston PK, Muñoz-Rojas AR, Jayewickreme T, Lazar MA, Benoist C, Mathis D. Tregs in visceral adipose tissue up-regulate circadian-clock expression to promote fitness and enforce a diurnal rhythm of lipolysis. Sci Immunol. 2022 Sep 30;7(75):eabl7641. doi: 10.1126/sciimmunol.abl7641. Epub 2022 Sep 30. PMID: 36179011.

Jang A, Petrova B, Cheong TC, Zawadzki ME, Jones JK, Culhane AJ, Shipley FB, Chiarle R, Wong ET, Kanarek N, Lehtinen MK. Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy. Neuron. 2022 Oct 19;110(20):3288-3301.e8. doi: 10.1016/j.neuron.2022.08.009. Epub 2022 Sep 6. PMID: 36070751; PMCID: PMC9588748.

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Kamath T, Abdulraouf A, Burris SJ, Langlieb J, Gazestani V, Nadaf NM, Balderrama K, Vanderburg C, Macosko EZ. Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson's disease. Nat Neurosci. 2022 May;25(5):588-595. doi: 10.1038/s41593-022-01061-1. Epub 2022 May 5. PMID: 35513515; PMCID: PMC9076534.

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Kong E, Shepard M, McIntyre A. Turnover in Zero-Premium Status Among Health Insurance Marketplace Plans Available to Low-Income Enrollees. JAMA Health Forum. 2022 Apr 22;3(4):e220674. doi: 10.1001/jamahealthforum.2022.0674. Erratum in: JAMA Health Forum. 2022 May 27;3(5):e221616. PMID: 35977318; PMCID: PMC9034407

Hsia K, Kong E. Characterizing the Reaction of Doctors to COVID-19 on Twitter. J Quant Descr Digit Media. 2022;2:10.51685/jqd.2022.012. doi: 10.51685/jqd.2022.012. PMID: 35542174; PMCID: PMC9082619.

Ji Y, Kong E. US Hospital Characteristics Associated With Price Transparency Regulation Compliance. JAMA Health Forum. 2022 Jun 24;3(6):e221702. doi: 10.1001/jamahealthforum.2022.1702. PMID: 35977242; PMCID: PMC9233236.

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Kim J, Huang AY, Johnson SL, Lai J, Isacco L, Jeffries AM, Miller MB, Lodato MA, Walsh CA, Lee EA. Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders. Nat Commun. 2022 Oct 7;13(1):5918. doi: 10.1038/s41467-022-33642-w. PMID: 36207339; PMCID: PMC9546902.

Bourseguin J, Cheng W, Talbot E, Hardy L, Lai J, Jeffries AM, Lodato MA, Lee EA, Khoronenkova SV. Persistent DNA damage associated with ATM kinase deficiency promotes microglial dysfunction. Nucleic Acids Res. 2022 Mar 21;50(5):2700-2718. doi: 10.1093/nar/gkac104. PMID: 35212385; PMCID: PMC8934660.

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Gazal S, Weissbrod O, Hormozdiari F, Dey KK, Nasser J, Jagadeesh KA, Weiner DJ, Shi H, Fulco CP, O'Connor LJ, Pasaniuc B, Engreitz JM, Price AL. Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity. Nat Genet. 2022 Jun;54(6):827-836. doi: 10.1038/s41588-022-01087-y. Epub 2022 Jun 6. PMID: 35668300.

Weiner DJ, Gazal S, Robinson EB, O'Connor LJ. Partitioning gene-mediated disease heritability without eQTLs. Am J Hum Genet. 2022 Mar 3;109(3):405-416. doi: 10.1016/j.ajhg.2022.01.010. Epub 2022 Feb 9. PMID: 35143757; PMCID: PMC8948166.

Weiner DJ, Ling E, Erdin S, Tai DJC, Yadav R, Grove J, Fu JM, Nadig A, Carey CE, Baya N, Bybjerg-Grauholm J; iPSYCH Consortium; ASD Working Group of the Psychiatric Genomics Consortium; ADHD Working Group of the Psychiatric Genomics Consortium; Berretta S, Macosko EZ, Sebat J, O'Connor LJ, Hougaard DM, Børglum AD, Talkowski ME, McCarroll SA, Robinson EB. Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p. Nat Genet. 2022 Nov;54(11):1630-1639. doi: 10.1038/s41588-022-01203-y. Epub 2022 Oct 24. PMID: 36280734; PMCID: PMC9649437.

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Winter CC, He Z, Jacobi A. Axon Regeneration: A Subcellular Extension in Multiple Dimensions. Cold Spring Harb Perspect Biol. 2022 Mar 1;14(3):a040923. doi: 10.1101/cshperspect.a040923. PMID: 34518340; PMCID: PMC8886981.

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Zawadzki M, Lehtinen MK. Young cerebrospinal fluid improves memory in old mice. Nature. 2022 May;605(7910):428-429. doi: 10.1038/d41586-022-00860-7. PMID: 35546616.

Jang A, Petrova B, Cheong TC, Zawadzki ME, Jones JK, Culhane AJ, Shipley FB, Chiarle R, Wong ET, Kanarek N, Lehtinen MK. Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy. Neuron. 2022 Oct 19;110(20):3288-3301.e8. doi: 10.1016/j.neuron.2022.08.009. Epub 2022 Sep 6. PMID: 36070751; PMCID: PMC9588748.

Gordon KS, Kyung T, Perez CR, Holec PV, Ramos A, Zhang AQ, Agarwal Y, Liu Y, Koch CE, Starchenko A, Joughin BA, Lauffenburger DA, Irvine DJ, Hemann MT, Birnbaum ME. Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains. Nat Biomed Eng. 2022 Jul;6(7):855-866. doi: 10.1038/s41551-022-00896-0. Epub 2022 Jun 16. PMID: 35710755.

Perez-Sanchez C, Barbera Betancourt A, Lyons PA, Zhang Z, Suo C, Lee JC, McKinney EF, Modis LK, Ellson C, Smith KGC. miR-374a-5p regulates inflammatory genes and monocyte function in patients with inflammatory bowel disease. J Exp Med. 2022 May 2;219(5):e20211366. doi: 10.1084/jem.20211366. Epub 2022 Apr 1. PMID: 35363256; PMCID: PMC8980842.

Zhang ZZ, Hashemi DA, Kroshinsky D. Disseminated Lyme disease with a herpetiform center. JAAD Case Rep. 2022 Mar 12;29:46-47. doi: 10.1016/j.jdcr.2022.02.034. PMID: 36193244; PMCID: PMC9525727.

Naranbhai V, Nathan A, Kaseke C, Berrios C, Khatri A, Choi S, Getz MA, Tano-Menka R, Ofoman O, Gayton A, Senjobe F, Zhao Z, St Denis KJ, Lam EC, Carrington M, Garcia-Beltran WF, Balazs AB, Walker BD, Iafrate AJ, Gaiha GD. T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals. Cell. 2022 Mar 31;185(7):1259. doi: 10.1016/j.cell.2022.03.022. Erratum for: Cell. 2022 Mar 17;185(6):1041-1051.e6. PMID: 35364034; PMCID: PMC8969090.

Naranbhai V, Nathan A, Kaseke C, Berrios C, Khatri A, Choi S, Getz MA, Tano-Menka R, Ofoman O, Gayton A, Senjobe F, Zhao Z, St Denis KJ, Lam EC, Carrington M, Garcia-Beltran WF, Balazs AB, Walker BD, Iafrate AJ, Gaiha GD. T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals. Cell. 2022 Mar 17;185(6):1041-1051.e6. doi: 10.1016/j.cell.2022.01.029. Epub 2022 Feb 3. Erratum in: Cell. 2022 Mar 31;185(7):1259. PMID: 35202566; PMCID: PMC8810349.

Chakladar J, Diomino A, Li WT, Tsai JC, Krishnan AR, Zou AE, Kharidia K, Baig FA, Householder S, Kuo SZ, Chandrasekar S, Chang EY, Ongkeko WM. Medical student's perception of the COVID-19 pandemic effect on their education and well-being: a cross-sectional survey in the United States. BMC Med Educ. 2022 Mar 5;22(1):149. doi: 10.1186/s12909-022-03197-x. PMID: 35248030; PMCID: PMC8897763.

Pfirschke C, Zilionis R, Engblom C, Messemaker M, Zou AE, Rickelt S, Gort-Freitas NA, Lin Y, Bill R, Siwicki M, Gungabeesoon J, Sprachman MM, Marquard AN, Rodell CB, Cuccarese MF, Quintana J, Ahmed MS, Kohler RH, Savova V, Weissleder R, Klein AM, Pittet MJ. Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells. Cancer Immunol Res. 2022 Jan;10(1):40-55. doi: 10.1158/2326-6066.CIR-21-0326. Epub 2021 Dec 1. PMID: 34795032.

Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C. The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma. Mol Cell. 2022 May 5;82(9):1737-1750.e8. doi: 10.1016/j.molcel.2022.03.019. Epub 2022 Apr 6. PMID: 35390276.

2021

Agarwal R, Paulo JA, Toepfer CN, Ewoldt JK, Sundaram S, Chopra A, Zhang Q, Gorham J, DePalma SR, Chen CS, Gygi SP, Seidman CE, Seidman JG. Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation. Circ Res. 2021 Sep 17;129(7):751-766. doi: 10.1161/CIRCRESAHA.120.317076. Epub 2021 Aug 18. PMID: 34405687.

Ahuja Y, Kim N, Liang L, Cai T, Dahal K, Seyok T, Lin C, Finan S, Liao K, Savovoa G, Chitnis T, Cai T, Xia Z. Leveraging electronic health records data to predict multiple sclerosis disease activity. Ann Clin Transl Neurol. 2021 Apr;8(4):800-810. doi: 10.1002/acn3.51324. Epub 2021 Feb 24. PMID: 33626237; PMCID: PMC8045951.

Akama-Garren EH, Li JX. Unbiased identification of clinical characteristics predictive of COVID-19 severity. Clin Exp Med. 2021 Jun 5:1–13. doi: 10.1007/s10238-021-00730-y. Epub ahead of print. PMID: 34089403; PMCID: PMC8178667.

Akama-Garren EH, Shah SA, Zinzuwadia AN, Bartuska A, Hashimoto M, Chu JT, Kruse GR, Cohen MJ. Outcomes of a Student-Led Telemedicine Clinic in Response to COVID-19. J Ambul Care Manage. 2021 Jul-Sep 01;44(3):197-206. doi: 10.1097/JAC.0000000000000380. PMID: 34016847; PMCID: PMC8148224.

Akama-Garren EH, Li JX. Prior immunosuppressive therapy is associated with mortality in COVID-19 patients: A retrospective study of 835 patients. J Med Virol. 2021 May 27. doi: 10.1002/jmv.27105. Epub ahead of print. PMID: 34042195.

Akama-Garren EH, Morris ZS, Sikora AG, Weichselbaum R, Schoenfeld JD. Prospective Clinical Investigation of the Efficacy of Combination Radiation Therapy With Immune Checkpoint Inhibition. Int J Radiat Oncol Biol Phys. 2021 Aug 16:S0360-3016(21)02648-1. doi: 10.1016/j.ijrobp.2021.08.009. Epub ahead of print. PMID: 34411638.

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Wagner A, Wang C, Fessler J, DeTomaso D, Avila-Pacheco J, Kaminski J, Zaghouani S, Christian E, Thakore P, Schellhaass B, Akama-Garren E, Pierce K, Singh V, Ron-Harel N, Douglas VP, Bod L, Schnell A, Puleston D, Sobel RA, Haigis M, Pearce EL, Soleimani M, Clish C, Regev A, Kuchroo VK, Yosef N. Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell. 2021 Aug 5;184(16):4168-4185.e21. doi: 10.1016/j.cell.2021.05.045. Epub 2021 Jul 2. PubMed PMID: 34216539.

Qian JM, Akama-Garren E, Shin J, Gunasti L, Bang A, Pike LRG, Grassberger C, Schoenfeld JD. Dosimetric Modeling of Lymphopenia in Patients With Metastatic Cancer Receiving Palliative Radiation and PD-1 Immune Checkpoint Inhibitors. Adv Radiat Oncol. 2021 Dec 24;7(2):100880. doi: 10.1016/j.adro.2021.100880. PMID: 35097241; PMCID: PMC8783121.

Akama-Garren EH, van den Broek T, Simoni L, Castrillon C, van der Poel CE, Carroll MC. Follicular T cells are clonally and transcriptionally distinct in B cell-driven mouse autoimmune disease. Nat Commun. 2021 Nov 18;12(1):6687. doi: 10.1038/s41467-021-27035-8. PMID: 34795279; PMCID: PMC8602266.

Smith RS, Florio M, Akula SK, Neil JE, Wang Y, Hill RS, Goldman M, Mullally CD, Reed N, Bello-Espinosa L, Flores-Sarnat L, Monteiro FP, Erasmo CB, Pinto E Vairo F, Morava E, Barkovich AJ, Gonzalez-Heydrich J, Brownstein CA, McCarroll SA, Walsh CA. Early role for a Na+,K+-ATPase (ATP1A3) in brain development. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25). doi: 10.1073/pnas.2023333118. PubMed PMID: 34161264; PubMed Central PMCID: PMC8237684.

Ebrahimi-Fakhari D, Alecu JE, Ziegler M, Geisel G, Jordan C, D'Amore A, Yeh RC, Akula SK, Saffari A, Prabhu SP, Sahin M, Yang E; International AP-4-HSP Registry and Natural History Study. Systematic Analysis of Brain MRI Findings in Adaptor Protein Complex 4-Associated Hereditary Spastic Paraplegia. Neurology. 2021 Sep 20:10.1212/WNL.0000000000012836. doi: 10.1212/WNL.0000000000012836. Epub ahead of print. PMID: 34544818.

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Choudhery S, Brown AJ, Akusobi C, Rubin EJ, Sassetti CM, Ioerger TR. Modeling Site-Specific Nucleotide Biases Affecting Himar1 Transposon Insertion Frequencies in TnSeq Data Sets. mSystems. 2021 Oct 26;6(5):e0087621. doi: 10.1128/mSystems.00876-21. Epub 2021 Oct 19. PMID: 34665010; PMCID: PMC8525568.

Rubin EJ, Baden LR, Del Rio C, Akusobi C, Morrissey S. Audio Interview: Delivering Covid-19 Vaccines to Minority Communities. N Engl J Med. 2021 Apr 1;384(13):e60. doi: 10.1056/NEJMe2105496. PMID: 33789019.

Alkaitis MS, Agrawal MN, Riely GJ, Razavi P, Sontag D. Automated NLP Extraction of Clinical Rationale for Treatment Discontinuation in Breast Cancer. JCO Clin Cancer Inform. 2021 May;5:550-560. doi: 10.1200/CCI.20.00139. PMID: 33989016.

Gui M, Farley H, Anujan P, Anderson JR, Maxwell DW, Whitchurch JB, Botsch JJ, Qiu T, Meleppattu S, Singh SK, Zhang Q, Thompson J, Lucas JS, Bingle CD, Norris DP, Roy S, Brown A. De novo identification of mammalian ciliary motility proteins using cryo-EM. Cell. 2021 Nov 11;184(23):5791-5806.e19. doi: 10.1016/j.cell.2021.10.007. Epub 2021 Oct 28. PMID: 34715025.

Rigney G, Ayubcha C, Werner TJ, Alavi A. An Update on the State of Tau Radiotracer Development: a Brief Review. Mol Imaging Biol. 2021 May 13. doi: 10.1007/s11307-021-01612-1. Epub ahead of print. PMID: 33987775.

Ayubcha C, Moghbel M, Borja AJ, Newberg A, Werner TJ, Alavi A, Revheim ME. Tau Imaging in Head Injury. PET Clin. 2021 Apr;16(2):249-260. doi: 10.1016/j.cpet.2020.12.009. PMID: 33648666.

Borja AJ, Hancin EC, Raynor WY, Ayubcha C, Detchou DK, Werner TJ, Revheim ME, Alavi A. A Critical Review of PET Tracers Used for Brain Tumor Imaging. PET Clin. 2021 Apr;16(2):219-231. doi: 10.1016/j.cpet.2020.12.004. Epub 2021 Feb 13. PMID: 33589386.

Arani LS, Zirakchian Zadeh M, Saboury B, Revheim ME, Øestergaard B, Borja AJ, Samadi Samarin D, Mehdizadeh Seraj S, Kalbush E, Ayubcha C, Morris MA, Werner TJ, Abildgaard N, Høilund-Carlsen PF, Alavi A. Assessment of atherosclerosis in multiple myeloma and smoldering myeloma patients using 18F- sodium fluoride PET/CT. J Nucl Cardiol. 2021 Jan 3. doi: 10.1007/s12350-020-02446-0. Epub ahead of print. PMID: 33389640.

Ayubcha C, Raynor WY, Borja AJ, Seraj SM, Rojulpote C, Werner TJ, Revheim ME, Rajapakse CS, Alavi A. Magnetic resonance imaging-based partial volume-corrected 18F-sodium fluoride positron emission tomography in the femoral neck. Nucl Med Commun. 2021 Apr 1;42(4):416-420. doi: 10.1097/MNM.0000000000001344. PMID: 33306627.

Ayubcha C, Pouladvand P, Ayubcha S. A Quasi-Experimental Study of Medicaid Expansion and Urban Mortality in the American Northeast. Front Public Health. 2021 Nov 17;9:707907. doi: 10.3389/fpubh.2021.707907. PMID: 34869142; PMCID: PMC8637894.

Ayubcha C, Rigney G, Borja AJ, Werner T, Alavi A. Tau-PET imaging as a molecular modality for Alzheimer's disease. Am J Nucl Med Mol Imaging. 2021 Oct 15;11(5):374-386. PMID: 34754608; PMCID: PMC8569333.

Bent EH, Millán-Barea LR, Zhuang I, Goulet DR, Fröse J, Hemann MT. Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy. Nat Commun. 2021 Oct 28;12(1):6218. doi: 10.1038/s41467-021-26407-4. PMID: 34711820; PMCID: PMC8553783.

Martin JR, Howard MT, Wang S, Berger AG, Hammond PT. Oxidation-Responsive, Tunable Growth Factor Delivery from Polyelectrolyte-Coated Implants. Adv Healthc Mater. 2021 May;10(9):e2001941. doi: 10.1002/adhm.202001941. Epub 2021 Mar 18. PMID: 33738985.

Chou JJ*, Berger AG*, Jalili-Firoozinezhad S, Hammond PT. A design approach for layer-by-layer surface-mediated siRNA delivery. Acta Biomater. 2021 Sep 1:S1742-7061(21)00575-4. doi: 10.1016/j.actbio.2021.08.042. Epub ahead of print. PMID: 34481054.

Zeleznik OA, Balasubramanian R, Ren Y, Tobias DK, Rosner BA, Peng C, Bever AM, Frueh L, Jeanfavre S, Avila-Pacheco J, Clish CB, Mora S, Hu FB, Eliassen AH. Branched-Chain Amino Acids and Risk of Breast Cancer. JNCI Cancer Spectr. 2021 Jul 2;5(5):pkab059. doi: 10.1093/jncics/pkab059. PMID: 34585062; PMCID: PMC8460878.

Bever AM, Hang D, He X, Joshi AD, Ding M, Wu K, Chan AT, Giovannucci EL, Song M. Genetic Obesity Variants and Risk of Conventional Adenomas and Serrated Polyps. Dig Dis Sci. 2021 Aug 17. doi: 10.1007/s10620-021-07193-x. Epub ahead of print. PMID: 34403030.

Bever AM, Cassidy A, Rimm EB, Stampfer MJ, Cote DJ. A prospective study of dietary flavonoid intake and risk of glioma in US men and women. Am J Clin Nutr. 2021 Oct 4;114(4):1314-1327. doi: 10.1093/ajcn/nqab178. PMID: 34113960; PMCID: PMC8488865.

Kragel EA, Beyer LN. Communicating About COVID-19 Through Art: Paving the Way for Inclusion. Acad Med. 2021 Jun 1;96(6):784. doi: 10.1097/ACM.0000000000003945. PMID: 33496436; PMCID: PMC8140640.

Botelho A. The Insights of Radical Science in the CRISPR Gene-Editing Era: A History of Science for the People and the Cambridge Recombinant DNA Controversy. Sci Cult (Lond). 2021;30(1):74-103. doi: 10.1080/09505431.2019.1623190. Epub 2019 Jun 7. PMID: 34239225; PMCID: PMC8259112.

Brinkmann R, Podolsky SH. The 'personal equation' as observer bias, and proposed methods to contain it in Anglo-American medicine. J R Soc Med. 2021 Oct;114(10):480-484. doi: 10.1177/01410768211049968. PMID: 34672818; PMCID: PMC8543575.

Garcia-Beltran WF, Lam EC, Astudillo MG, Yang D, Miller TE, Feldman J, Hauser BM, Caradonna TM, Clayton KL, Nitido AD, Murali MR, Alter G, Charles RC, Dighe A, Branda JA, Lennerz JK, Lingwood D, Schmidt AG, Iafrate AJ, Balazs AB. COVID-19-neutralizing antibodies predict disease severity and survival. Cell. 2021 Jan 21;184(2):476-488.e11. doi: 10.1016/j.cell.2020.12.015. Epub 2020 Dec 15. PMID: 33412089; PMCID: PMC7837114.

Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Rapid generation of potent antibodies by autonomous hypermutation in yeast. Nat Chem Biol. 2021 Jun 24. doi: 10.1038/s41589-021-00832-4. Epub ahead of print. PMID: 34168368.

Amraei R, Yin W, Napoleon MA, Suder EL, Berrigan J, Zhao Q, Olejnik J, Chandler KB, Xia C, Feldman J, Hauser BM, Caradonna TM, Schmidt AG, Gummuluru S, Mühlberger E, Chitalia V, Costello CE, Rahimi N. CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2. ACS Cent Sci. 2021 Jul 28;7(7):1156-1165. doi: 10.1021/acscentsci.0c01537. Epub 2021 Jun 30. PMID: 34341769; PMCID: PMC8265543.

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Hayirli TC, Stark N, Bhanja A, Hardy J, Peabody CR, Kerrissey MJ. Masked and distanced: a qualitative study of how personal protective equipment and distancing affect teamwork in emergency care. Int J Qual Health Care. 2021 Apr 28;33(2):mzab069. doi: 10.1093/intqhc/mzab069. PMID: 33864362; PMCID: PMC8083305.

Hayirli TC, Meara JG, Barash D, Chirangi B, Hellar A, Kenemo B, Kissima I, Maongezi S, Reynolds C, Samky H, Ulisubisya M, Varallo JE, Warinner CB, Alidina S, Kapologwe NA. Development and content validation of the Safe Surgery Organizational Readiness Tool: A quality improvement study. Int J Surg. 2021 May;89:105944. doi: 10.1016/j.ijsu.2021.105944. Epub 2021 Apr 14. PMID: 33862259.

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Hayirli T, Anderson B. 10 minutes with Dr. Brian Anderson, Chief Digital Health Physician at the MITRE Corporation, Massachusetts, USA. BMJ Leader 2021;5:219-220.

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Hauser BM*, Hoffman SE* Gupta S, Zaki MM, Xu E, Chua M, Bernstock JD, Khawaja A, Smith TR, Proctor MR, Zaidi HA. Association of venous thromboembolism following pediatric traumatic spinal injuries with injury severity and longer hospital stays. J Neurosurg Spine. 2021 Sep 17:1-7. doi: 10.3171/2021.3.SPINE201981. Epub ahead of print. PMID: 34534962.

Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Bi WL. A Molecularly Integrated Grade for Meningioma. Neuro Oncol. 2021 Sep 11:noab213. doi: 10.1093/neuonc/noab213. Epub ahead of print. PMID: 34508644.

Hoffman SE, Gupta S, Huang K, Klinger N, Lu Y. Three-dimensional Navigation-guided, Prone, Single-position, Lateral Lumbar Interbody Fusion Technique. J Vis Exp. 2021 Jul 15;(173). doi: 10.3791/62662. PMID: 34338679.

Bernstock JD, Hoffman SE, Chen JA, Gupta S, Kappel AD, Smith TR, Chiocca EA. The Current Landscape of Oncolytic Herpes Simplex Viruses as Novel Therapies for Brain Malignancies. Viruses. 2021 Jun 17;13(6):1158. doi: 10.3390/v13061158. PMID: 34204248; PMCID: PMC8234451.

Bi WL, Nayak L, Meredith DM, Driver J, Du Z, Hoffman S, Li Y, Lee EQ, Beroukhim R, Rinne M, McFaline-Figueroa R, Chukwueke U, McCluskey C, Gaffey S, Cherniack AD, Stefanik J, Doherty L, Taubert C, Cifrino M, LaFrankie D, Graillon T, Wen PY, Ligon KL, Al-Mefty O, Huang RY, Muzikansky A, Chiocca EA, Santagata S, Dunn IF, Reardon DA. Activity of PD-1 blockade with Nivolumab among patients with recurrent atypical/anaplastic meningioma: Phase II trial results. Neuro Oncol. 2021 May 20:noab118. doi: 10.1093/neuonc/noab118. Epub ahead of print. PMID: 34015129.

Feng R, Hoffman SE, Wagner K, Ullman JS, Stippler M, Germano IM. Women Neurosurgeons in Academic and Other Leadership Positions in the United States. World Neurosurg. 2021 Mar;147:80-88. doi: 10.1016/j.wneu.2020.12.069. Epub 2020 Dec 21. PMID: 33358734.

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Smati H, Cohen PA, Nagda DV, Saravanan Y, Kalugin PN, Li CY, Ranker LR. Risk Factors for Hospitalization Among Patients with COVID-19 at a Community Ambulatory Clinic in Massachusetts During the Initial Pandemic Surge. J Immigr Minor Health. 2021 Oct;23(5):1110-1115. doi: 10.1007/s10903-021-01189-5. Epub 2021 Mar 26. PMID: 33772419; PMCID: PMC7996715.

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Kang JB, Nathan A, Weinand K, Zhang F, Millard N, Rumker L, Moody DB, Korsunsky I, Raychaudhuri S. Efficient and precise single-cell reference atlas mapping with Symphony. Nat Commun. 2021 Oct 7;12(1):5890. doi: 10.1038/s41467-021-25957-x. PMID: 34620862.

Reshef YA, Rumker L, Kang JB, Nathan A, Korsunsky I, Asgari S, Murray MB, Moody DB, Raychaudhuri S. Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics. Nat Biotechnol. 2021 Oct 21. doi: 10.1038/s41587-021-01066-4. Epub ahead of print. PMID: 34675423.

Millard N, Korsunsky I, Weinand K, Fonseka CY, Nathan A, Kang JB, Raychaudhuri S. Maximizing statistical power to detect differentially abundant cell states with scPOST. Cell Rep Methods. 2021 Nov 16;1(8):100120. doi: 10.1016/j.crmeth.2021.100120. Epub 2021 Nov 22. PMID: 35005693; PMCID: PMC8740883

Burger ML, Cruz AM, Crossland GE, Gaglia G, Ritch CC, Blatt SE, Bhutkar A, Canner D, Kienka T, Tavana SZ, Barandiaran AL, Garmilla A, Schenkel JM, Hillman M, de Los Rios Kobara I, Li A, Jaeger AM, Hwang WL, Westcott PMK, Manos MP, Holovatska MM, Hodi FS, Regev A, Santagata S, Jacks T. Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors. Cell. 2021 Sep 16;184(19):4996-5014.e26. doi: 10.1016/j.cell.2021.08.020. PMID: 34534464; PMCID: PMC8522630.

Zhang Y, Guo R, Kim SH, Shah H, Zhang S, Liang JH, Fang Y, Gentili M, Leary CNO, Elledge SJ, Hung DT, Mootha VK, Gewurz BE. SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nat Commun. 2021 Mar 15;12(1):1676. doi: 10.1038/s41467-021-21903-z. PMID: 33723254; PMCID: PMC7960988.

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Tothova Z, Valton AL, Gorelov RA, Vallurupalli M, Krill-Burger JM, Holmes A, Landers CC, Haydu JE, Malolepsza E, Hartigan C, Donahue M, Popova KD, Koochaki S, Venev SV, Rivera J, Chen E, Lage K, Schenone M, D'Andrea AD, Carr SA, Morgan EA, Dekker J, Ebert BL. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. JCI Insight. 2021 Feb 8;6(3):e142149. doi: 10.1172/jci.insight.142149. PMID: 33351783; PMCID: PMC7934867.

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Kotliar D, Colubri A. Sciviewer enables interactive visual interrogation of single-cell RNA-Seq data from the python programming environment. Bioinformatics. 2021 Oct 2:btab689. doi: 10.1093/bioinformatics/btab689. Epub ahead of print. PMID: 34601589

Tan CL*, Kuchroo JR*, Sage PT, Liang D, Francisco LM, Buck J, Thaker YR, Zhang Q, McArdel SL, Juneja VR, Lee SJ, Lovitch SB, Lian C, Murphy GF, Blazar BR, Vignali DAA, Freeman GJ, Sharpe AH. PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance. J Exp Med. 2021 Jan 4;218(1):e20182232. doi: 10.1084/jem.20182232. PMID: 33045061; PMCID: PMC7543091.

Kuchroo JR, Hafler DA, Sharpe AH, Lucca LE. The double-edged sword: Harnessing PD-1 blockade in tumor and autoimmunity. Sci Immunol. 2021 Nov 5;6(65):eabf4034. doi: 10.1126/sciimmunol.abf4034. Epub 2021 Nov 5. PMID: 34739340.

Thompson LL, Krasnow NA, Chang MS, Yoon J, Li EB, Polyakov NJ, Molina GE, Said JT, Huang K, Kuchroo JR, Hinton AN, Reynolds KL, Chen ST. Patterns of Cutaneous and Noncutaneous Immune-Related Adverse Events Among Patients With Advanced Cancer. JAMA Dermatol. 2021 May 1;157(5):577-582. doi: 10.1001/jamadermatol.2021.0326. PMID: 33760001; PMCID: PMC7992016.

Thompson LL, Chang MS, Polyakov NJ, Blum AE, Josephs N, Krasnow NA, Yoon J, Li EB, Molina GE, Said JT, Huang K, Kuchroo JR, Hinton AN, Chen ST. Prognostic significance of cutaneous immune-related adverse events in patients with melanoma and other cancers on immune checkpoint inhibitors. J Am Acad Dermatol. 2021 Mar 17:S0190-9622(21)00563-6. doi: 10.1016/j.jaad.2021.03.024. Epub ahead of print. PMID: 33722547.

Pauken KE, Shahid O, Lagattuta KA, Mahuron KM, Luber JM, Lowe MM, Huang L, Delaney C, Long JM, Fung ME, Newcomer K, Tsai KK, Chow M, Guinn S, Kuchroo JR, Burke KP, Schenkel JM, Rosenblum MD, Daud AI, Sharpe AH, Singer M. Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment. J Exp Med. 2021 Apr 5;218(4):e20200920. doi: 10.1084/jem.20200920. PMID: 33651880; PMCID: PMC7933992.

Ryu S, Martino N, Kwok SJJ, Bernstein L, Yun SH. Label-free histological imaging of tissues using Brillouin light scattering contrast. Biomed Opt Express. 2021 Feb 17;12(3):1437-1448. doi: 10.1364/BOE.414474. PMID: 33796364; PMCID: PMC7984781.

Lagattuta KA, Nigrovic PA. Estrogen-Driven Changes in Immunoglobulin G Fc Glycosylation. Exp Suppl. 2021;112:341-361. doi: 10.1007/978-3-030-76912-3_11. PMID: 34687016.

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Lee SJ, Lodder B, Chen Y, Patriarchi T, Tian L, Sabatini BL. Cell-type-specific asynchronous modulation of PKA by dopamine in learning. Nature. 2021 Feb;590(7846):451-456. doi: 10.1038/s41586-020-03050-5. Epub 2020 Dec 23. PMID: 33361810; PMCID: PMC7889726.

Lenehan PJ, Cirella A, Uchida AM, Crowley SJ, Sharova T, Boland G, Dougan M, Dougan SK, Heckler M. Type 2 immunity is maintained during cancer-associated adipose tissue wasting. Immunother Adv. 2021 Jun 2;1(1):ltab011. doi: 10.1093/immadv/ltab011. PMID: 34291232; PMCID: PMC8286632.

Uchida AM, Lenehan PJ, Vimalathas P, Miller KC, Valencia-Yang M, Qiang L, Canha LA, Ali LR, Dougan M, Garber JJ, Dougan SK. Tissue eosinophils express the IL-33 receptor ST2 and type 2 cytokines in patients with eosinophilic esophagitis. Allergy. 2021 Oct 6. doi: 10.1111/all.15127. Epub ahead of print. PMID: 34614218.

Ganesh R, Pawlowski CF, O'Horo JC, Arndt LL, Arndt RF, Bell SJ, Bierle DM, Borgen MD, Hanson SN, Heyliger A, Larsen JJ, Lenehan PJ, Orenstein R, Puranik A, Speicher LL, Tulledge-Scheitel SM, Venkatakrishnan AJ, Wilker CG, Badley AD, Razonable RR. Intravenous bamlanivimab use associates with reduced hospitalization in high-risk patients with mild to moderate COVID-19. J Clin Invest. 2021 Oct 1;131(19):e151697. doi: 10.1172/JCI151697. PMID: 34411003; PMCID: PMC8483756.

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Liu R, Paz M, Siraj L, Boyd T, Salamone S, Lite TV, Leung KM, Chirinos JD, Shang HH, Townsend MJ, Rho J, Ni P, Ranganath K, Violante AD, Zhao Z, Silvernale C, Ahmad I, Krasnow NA, Barnett ES, Harisinghani M, Kuo B, Black KE, Staller K. Feeding intolerance in critically ill patients with COVID-19. Clin Nutr. 2021 Mar 29:S0261-5614(21)00180-1. doi: 10.1016/j.clnu.2021.03.033. Epub ahead of print. PMID: 33934924; PMCID: PMC8007186

Alhazmi N, Carroll SH, Kawasaki K, Woronowicz KC, Hallett SA, Macias Trevino C, Li EB, Baron R, Gori F, Yelick PC, Harris MP, Liao EC. Synergistic roles of Wnt modulators R-spondin2 and R-spondin3 in craniofacial morphogenesis and dental development. Sci Rep. 2021 Mar 12;11(1):5871. doi: 10.1038/s41598-021-85415-y. PMID: 33712657; PMCID: PMC7954795.

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Liu R, Paz M, Siraj L, Boyd T, Salamone S, Lite TV, Leung KM, Chirinos JD, Shang HH, Townsend MJ, Rho J, Ni P, Ranganath K, Violante AD, Zhao Z, Silvernale C, Ahmad I, Krasnow NA, Barnett ES, Harisinghani M, Kuo B, Black KE, Staller K. Feeding intolerance in critically ill patients with COVID-19. Clin Nutr. 2021 Mar 29:S0261-5614(21)00180-1. doi: 10.1016/j.clnu.2021.03.033. Epub ahead of print. PMID: 33934924; PMCID: PMC8007186

Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Sci Transl Med. 2021 Feb 17;13(581):eabd8636. doi: 10.1126/scitranslmed.abd8636. PMID: 33597266; PMCID: PMC8130008.

Beaulieu-Laroche L, Brown NJ, Hansen M, Toloza EHS, Sharma J, Williams ZM, Frosch MP, Cosgrove GR, Cash SS, Harnett MT. Allometric rules for mammalian cortical layer 5 neuron biophysics. Nature. 2021 Dec;600(7888):274-278. doi: 10.1038/s41586-021-04072-3. Epub 2021 Nov 10. PMID: 34759318; PMCID: PMC8665137.

Unger ES, Grabowski DC, Chen J, Berkman L. Association Between New-Onset Medicaid Home Care and Family Caregivers’ Health. JAMA health forum. 2021 September; 2(9):doi:10.1001/jamahealthforum.2021.2671. NIHMSID: NIHMS1784118.

Genadry KC, Shrock C, O'Shea D, Vatsa R, Shah AS, Gise R, Lipsett SC. Traumatic Hyphema. J Emerg Med. 2021 Dec;61(6):740-741. doi: 10.1016/j.jemermed.2021.07.041. Epub 2021 Sep 11. PMID: 34518051.

Lagomarsino VN, Pearse RV 2nd, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, Fancher SB, He A, Merchant JP, Duong DM, Martinez H, Zhou M, Bah F, Vicent MA, Stricker JMS, Xu J, Dammer EB, Levey AI, Chibnik LB, Menon V, Seyfried NT, De Jager PL, Noggle S, Selkoe DJ, Bennett DA, Young-Pearse TL. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron. 2021 Nov 3;109(21):3402-3420.e9. doi: 10.1016/j.neuron.2021.08.003. Epub 2021 Sep 1. PMID: 34473944; PMCID: PMC8571042.

Smith RS, Florio M, Akula SK, Neil JE, Wang Y, Hill RS, Goldman M, Mullally CD, Reed N, Bello-Espinosa L, Flores-Sarnat L, Monteiro FP, Erasmo CB, Pinto E Vairo F, Morava E, Barkovich AJ, Gonzalez-Heydrich J, Brownstein CA, McCarroll SA, Walsh CA. Early role for a Na+,K+-ATPase (ATP1A3) in brain development. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2023333118. doi: 10.1073/pnas.2023333118. PMID: 34161264; PMCID: PMC8237684.

Wartak A, Kelada AK, Leon Alarcon PA, Bablouzian AL, Ahsen OO, Gregg AL, Wei Y, Bollavaram K, Sheil CJ, Farewell E, VanTol S, Smith R, Grahmann P, Baillargeon AR, Gardecki JA, Tearney GJ. Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy. Biomed Opt Express. 2021 Jun 21;12(7):4308-4323. doi: 10.1364/BOE.422453. PMID: 34457416; PMCID: PMC8367220.

Yates KB, Tonnerre P, Martin GE, Gerdemann U, Al Abosy R, Comstock DE, Weiss SA, Wolski D, Tully DC, Chung RT, Allen TM, Kim AY, Fidler S, Fox J, Frater J, Lauer GM, Haining WN, Sen DR. Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans. Nat Immunol. 2021 Aug;22(8):1020-1029. doi: 10.1038/s41590-021-00979-1. Epub 2021 Jul 26. PMID: 34312547.

Collier JL, Weiss SA, Pauken KE, Sen DR, Sharpe AH. Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity. Nat Immunol. 2021 Jul;22(7):809-819. doi: 10.1038/s41590-021-00949-7. Epub 2021 Jun 17. PMID: 34140679; PMCID: PMC9197228.

Petrova B, Warren A, Vital NY, Culhane AJ, Maynard AG, Wong A, Kanarek N. Redox Metabolism Measurement in Mammalian Cells and Tissues by LC-MS. Metabolites. 2021 May 13;11(5):313. doi: 10.3390/metabo11050313. PMID: 34068241; PMCID: PMC8153172.

Yan Y, Ramanan D, Rozenberg M, McGovern K, Rastelli D, Vijaykumar B, Yaghi O, Voisin T, Mosaheb M, Chiu I, Itzkovitz S, Rao M, Mathis D, Benoist C. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. Immunity. 2021 Mar 9;54(3):499-513.e5. doi: 10.1016/j.immuni.2021.02.002. PMID: 33691135; PMCID: PMC8133394.

Zhang ZZ, Zhang Y, He T, Sweeney CL, Baris S, Karakoc-Aydiner E, Yao Y, Ertem D, Matthews HF, Gonzaga-Jauregui C, Malech HL, Su HC, Ozen A, Smith KGC, Lenardo MJ. Homozygous IL37 mutation associated with infantile inflammatory bowel disease. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2009217118. doi: 10.1073/pnas.2009217118. PMID: 33674380. PMCID: PMC7958356.

Zhang Z, Ortega D, Rush A, Blankenship LR, Cheng ZJ, Moore RE, Tran MLN, Sandoval LG, Aboulhosn K, Watanabe S, Cortez KS, Perlman DH, Semmelhack MF, Miller Conrad LC. Antibiotic Adjuvant Activity Revealed in a Photoaffinity Approach to Determine the Molecular Target of Antipyocyanin Compounds. ACS Infect Dis. 2021 Feb 15. doi: 10.1021/acsinfecdis.0c00160. Epub ahead of print. PMID: 33587590.

Ziegler CGK, Miao VN, Owings AH, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Christian T, Parker A, Sindel CB, Burger MW, Pride Y, Hasan M, Abraham GE 3rd, Senitko M, Robinson TO, Shalek AK, Glover SC, Horwitz BH, Ordovas-Montanes J. Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19. Cell. 2021 Jul 23:S0092-8674(21)00882-5. doi: 10.1016/j.cell.2021.07.023. Epub ahead of print. PMID: 34352228; PMCID: PMC8299217.

Huang S, Ziegler CGK, Austin J, Mannoun N, Vukovic M, Ordovas-Montanes J, Shalek AK, von Andrian UH. Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential. Cell. 2021 Jan 21;184(2):441-459.e25. doi: 10.1016/j.cell.2020.11.028. Epub 2020 Dec 16. PMID: 33333021.

Genshaft AS*, Ziegler CGK,* Tzouanas CN, Mead BE, Jaeger AM, Navia AW, King RP, Mana MD, Huang S, Mitsialis V, Snapper SB, Yilmaz ÖH, Jacks T, Van Humbeck JF, Shalek AK. Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. Nat Commun. 2021 Aug 17;12(1):4995. doi: 10.1038/s41467-021-25279-y. Erratum in: Nat Commun. 2021 Sep 3;12(1):5361. PMID: 34404785; PMCID: PMC8371137. *Co-first authors

Zhang AQ. Saying yes to help. Science. 2021 Jan 1;371(6524):98. doi: 10.1126/science.371.6524.98. PMID: 33384379.

Delorey TM*, Ziegler CGK*, Heimberg G*, Normand R, Yang Y*, Segerstolpe Å, Abbondanza D*, Fleming SJ*, Subramanian *A, Montoro DT*, Jagadeesh KA*, Dey KK*, Sen P*, Slyper M*, Pita-Juárez YH*, Phillips D*, Biermann J*, Bloom-Ackermann Z, Barkas N, Ganna A, Gomez J, Melms JC, Katsyv I, Normandin E, Naderi P, Popov YV, Raju SS, Niezen S, Tsai LT, Siddle KJ, Sud M, Tran VM, Vellarikkal SK, Wang Y, Amir-Zilberstein L, Atri DS, Beechem J, Brook OR, Chen J, Divakar P, Dorceus P, Engreitz JM, Essene A, Fitzgerald DM, Fropf R, Gazal S, Gould J, Grzyb J, Harvey T, Hecht J, Hether T, Jané-Valbuena J, Leney-Greene M, Ma H, McCabe C, McLoughlin DE, Miller EM, Muus C, Niemi M, Padera R, Pan L, Pant D, Pe'er C, Pfiffner-Borges J, Pinto CJ, Plaisted J, Reeves J, Ross M, Rudy M, Rueckert EH, Siciliano M, Sturm A, Todres E, Waghray A, Warren S, Zhang S, Zollinger DR, Cosimi L, Gupta RM, Hacohen N, Hibshoosh H, Hide W, Price AL, Rajagopal J, Tata PR, Riedel S, Szabo G, Tickle TL, Ellinor PT, Hung D, Sabeti PC, Novak R, Rogers R, Ingber DE, Jiang ZG, Juric D, Babadi M, Farhi SL, Izar B, Stone JR, Vlachos IS, Solomon IH, Ashenberg O, Porter CBM, Li B, Shalek AK, Villani AC, Rozenblatt-Rosen O, Regev A. COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature. 2021 Jul;595(7865):107-113. doi: 10.1038/s41586-021-03570-8. Epub 2021 Apr 29. PMID: 33915569; PMCID: PMC8919505. (*equal contribution)

Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED, Subramanian A, Smillie C, Jagadeesh KA, Duong ET, Fiskin E, Torlai Triglia E, Ansari M, Cai P, Lin B, Buchanan J, Chen S, Shu J, Haber AL, Chung H, Montoro DT, Adams T, Aliee H, Allon SJ, Andrusivova Z, Angelidis I, Ashenberg O, Bassler K, Bécavin C, Benhar I, Bergenstråhle J, Bergenstråhle L, Bolt L, Braun E, Bui LT, Callori S, Chaffin M, Chichelnitskiy E, Chiou J, Conlon TM, Cuoco MS, Cuomo ASE, Deprez M, Duclos G, Fine D, Fischer DS, Ghazanfar S, Gillich A, Giotti B, Gould J, Guo M, Gutierrez AJ, Habermann AC, Harvey T, He P, Hou X, Hu L, Hu Y, Jaiswal A, Ji L, Jiang P, Kapellos TS, Kuo CS, Larsson L, Leney-Greene MA, Lim K, Litviňuková M, Ludwig LS, Lukassen S, Luo W, Maatz H, Madissoon E, Mamanova L, Manakongtreecheep K, Leroy S, Mayr CH, Mbano IM, McAdams AM, Nabhan AN, Nyquist SK, Penland L, Poirion OB, Poli S, Qi C, Queen R, Reichart D, Rosas I, Schupp JC, Shea CV, Shi X, Sinha R, Sit RV, Slowikowski K, Slyper M, Smith NP, Sountoulidis A, Strunz M, Sullivan TB, Sun D, Talavera-López C, Tan P, Tantivit J, Travaglini KJ, Tucker NR, Vernon KA, Wadsworth MH, Waldman J, Wang X, Xu K, Yan W, Zhao W, Ziegler CGK; NHLBI LungMap Consortium; Human Cell Atlas Lung Biological Network. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat Med. 2021 Mar;27(3):546-559. doi: 10.1038/s41591-020-01227-z. Epub 2021 Mar 2. PMID: 33654293.

Rodel HE, Ferreira IATM, Ziegler CGK, Ganga Y, Bernstein M, Hwa SH, Nargan K, Lustig G, Kaplan G, Noursadeghi M, Shalek AK, Steyn AJC, Sigal A. Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response. Front Microbiol. 2021 Dec 2;12:757134. doi: 10.3389/fmicb.2021.757134. PMID: 34925266; PMCID: PMC8674758.

Bein A, Kim S, Goyal G, Cao W, Fadel C, Naziripour A, Sharma S, Swenor B, LoGrande N, Nurani A, Miao VN, Navia AW, Ziegler CGK, Montañes JO, Prabhala P, Kim MS, Prantil-Baun R, Rodas M, Jiang A, O'Sullivan L, Tillya G, Shalek AK, Ingber DE. Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip. Front Pharmacol. 2021 Oct 25;12:718484. doi: 10.3389/fphar.2021.718484. PMID: 34759819; PMCID: PMC8573067.

Bagati A, Kumar S, Jiang P, Pyrdol J, Zou AE, Godicelj A, Mathewson ND, Cartwright ANR, Cejas P, Brown M, Giobbie-Hurder A, Dillon D, Agudo J, Mittendorf EA, Liu XS, Wucherpfennig KW. Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer. Cancer Cell. 2021 Jan 11;39(1):54-67.e9. doi: 10.1016/j.ccell.2020.12.001. Epub 2020 Dec 31. PMID: 33385331; PMCID: PMC7855651.

Siwicki M, Gort-Freitas NA, Messemaker M, Bill R, Gungabeesoon J, Engblom C, Zilionis R, Garris C, Gerhard GM, Kohl A, Lin Y, Zou AE, Cianciaruso C, Bolli E, Pfirschke C, Lin YJ, Piot C, Mindur JE, Talele N, Kohler RH, Iwamoto Y, Mino-Kenudson M, Pai SI, deVito C, Koessler T, Merkler D, Coukos A, Wicky A, Fraga M, Sempoux C, Jain RK, Dietrich PY, Michielin O, Weissleder R, Klein AM, Pittet MJ. Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy. Sci Immunol. 2021 Jul 2;6(61):eabi7083. doi: 10.1126/sciimmunol.abi7083. PMID: 34215680; PMCID: PMC8845079.

2020

Morton SU, Agarwal R, Madden JA, Genetti CA, Brownstein CA, López-Giráldez F, Choi J, Seidman CE, Seidman JG, Lyon GJ, Agrawal PB. Congenital Heart Defects Due to TAF1 Missense Variants. Circ Genom Precis Med. 2020 Jun;13(3):e002843. doi: 10.1161/CIRCGEN.119.002843. Epub 2020 May 12. PMID: 32396742; PMCID: PMC7329268

Herkert JC, Verhagen JMA, Yotti R, Haghighi A, Phelan DG, James PA, Brown NJ, Stutterd C, Macciocca I, Leong K, Bulthuis MLC, van Bever Y, van Slegtenhorst MA, Boven LG, Roberts AE, Agarwal R, Seidman J, Lakdawala NK, Fernández-Avilés F, Burke MA, Pierpont ME, Braunlin E, ḈaÄŸlayan AO, Barge-Schaapveld DQCM, Birnie E, van Osch-Gevers L, van Langen IM, Jongbloed JDH, Lockhart PJ, Amor DJ, Seidman CE, van de Laar IMBH. Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants. Am Heart J. 2020 Jul;225:108-119. doi: 10.1016/j.ahj.2020.03.023. Epub 2020 Apr 21. PMID: 32480058.

Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JF, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation. 2020 Mar 10;141(10):828-842. doi: 10.1161/CIRCULATIONAHA.119.042339. Epub 2020 Jan 27. Erratum in: Circulation. 2020 Mar 10;141(10):e645. PMID: 31983222; PMCID: PMC7077965

Sharma A, Wasson LK, Willcox JA, Morton SU, Gorham JM, DeLaughter DM, Neyazi M, Schmid M, Agarwal R, Jang MY, Toepfer CN, Ward T, Kim Y, Pereira AC, DePalma SR, Tai A, Kim S, Conner D, Bernstein D, Gelb BD, Chung WK, Goldmuntz E, Porter G, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE; Pediatric Cardiac Genomics Consortium. GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm. Elife. 2020 Oct 15;9:e53278. doi: 10.7554/eLife.53278. PMID: 33054971; PMCID: PMC7593088.

Ahuja Y, Zhou D, He Z, Sun J, Castro VM, Gainer V, Murphy SN, Hong C, Cai T. sureLDA: A multidisease automated phenotyping method for the electronic health record. J Am Med Inform Assoc. 2020 Jun 17:ocaa079. doi: 10.1093/jamia/ocaa079. Epub ahead of print. PMID: 32548637.

Sonabend W A, Cai W, Ahuja Y, Ananthakrishnan A, Xia Z, Yu S, Hong C. Automated ICD coding via unsupervised knowledge integration (UNITE). Int J Med Inform. 2020 Jul;139:104135. doi: 10.1016/j.ijmedinf.2020.104135. Epub 2020 Apr 4. PMID: 32361145.

Li Y, Nair P, Lu XH, Wen Z, Wang Y, Dehaghi AAK, Miao Y, Liu W, Ordog T, Biernacka JM, Ryu E, Olson JE, Frye MA, Liu A, Guo L, Marelli A, Ahuja Y, Davila-Velderrain J, Kellis M. Inferring multimodal latent topics from electronic health records. Nat Commun. 2020 May 21;11(1):2536. doi: 10.1038/s41467-020-16378-3. PMID: 32439869; PMCID: PMC7242436.

Tedeschi SK, Cai T, He Z, Ahuja Y, Hong C, Yates KA, Dahal K, Xu C, Lyu H, Yoshida K, Solomon DH, Cai T, Liao KP. Classifying Pseudogout using Machine Learning Approaches with Electronic Health Record Data. Arthritis Care Res (Hoboken). 2020 Jan 7:10.1002/acr.24132. doi: 10.1002/acr.24132. Epub ahead of print. PMID: 31910317; PMCID: PMC7338229.

Huang AY, Li P, Rodin RE, Kim SN, Dou Y, Kenny CJ, Akula SK, Hodge RD, Bakken TE, Miller JA, Lein ES, Park PJ, Lee EA, Walsh CA. Parallel RNA and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):13886-13895. doi: 10.1073/pnas.2006163117. Epub 2020 Jun 10. PMID: 32522880; PMCID: PMC7322034.

Lin AE, Diehl WE, Cai Y, Finch CL, Akusobi C, Kirchdoerfer RN, Bollinger L, Schaffner SF, Brown EA, Saphire EO, Andersen KG, Kuhn JH, Luban J, Sabeti PC. Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111. Viruses. 2020 Jan 15;12(1):E105. doi: 10.3390/v12010105. PMID: 31952352.

Connor J, Madhavan S, Mokashi M, Amanuel H, Johnson NR, Pace LE, Bartz D. Health risks and outcomes that disproportionately affect women during the Covid-19 pandemic: A review. Soc Sci Med. 2020 Dec;266:113364. doi: 10.1016/j.socscimed.2020.113364. Epub 2020 Sep 13. PMID: 32950924; PMCID: PMC7487147

Greenfield DA, Schmidt HR, Skiba MA, Mandler MD, Anderson JR, Sliz P, Kruse AC. Virtual Screening for Ligand Discovery at the σ1 Receptor. ACS Med Chem Lett. 2020 Jul 27;11(8):1555-1561. doi: 10.1021/acsmedchemlett.9b00314. PMID: 32832023; PMCID: PMC7430954.

Berger AG, Chou JJ, Hammond PT. Approaches to Modulate the Chronic Wound Environment Using Localized Nucleic Acid Delivery. Adv Wound Care (New Rochelle). 2020 Jul 7. doi: 10.1089/wound.2020.1167. Epub ahead of print. PMID: 32496978.

Scott, K. W.*; Berger, A. G.*; Stuart, J. C.*; Hundert, E. M. Re-engaging students in medical school accreditation: the independent student analysis action (ISA2) approach. MedEdPublish. 2020.

Reardon R, Beyer L, Carpenter K, Irwin M, Kester K, Laird J, Moore C, Shah P, Conrad R. Medical Student Development of K-12 Educational Resources During the COVID-19 Pandemic. Acad Pediatr. 2020 Aug;20(6):763-764. doi: 10.1016/j.acap.2020.05.022. Epub 2020 Jun 2. PMID: 32502534; PMCID: PMC7266567.

Yip MCJ, Bodnar NO, Rapoport TA. Ddi1 is a ubiquitin-dependent protease. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7776-7781. doi: 10.1073/pnas.1902298117. Epub 2020 Mar 19. PMID: 32193351; PMCID: PMC7149228.

Holmgren AJ, Botelho A, Brandt AM. A History of Prescription Drug Monitoring Programs in the United States: Political Appeal and Public Health Efficacy. Am J Public Health. 2020 Aug;110(8):1191-1197. doi: 10.2105/AJPH.2020.305696. Epub 2020 Jun 18. PMID: 32552023; PMCID: PMC7349461.

Brandt AM, Botelho A. Not a Perfect Storm - Covid-19 and the Importance of Language. N Engl J Med. 2020 Apr 16;382(16):1493-1495. doi: 10.1056/NEJMp2005032. PMID: 32294345.

Li Y, Ivica NA, Dong T, Papageorgiou DP, He Y, Brown DR, Kleyman M, Hu G, Chen WW, Sullivan LB, Del Rosario A, Hammond PT, Vander Heiden MG, Chen J. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nat Commun. 2020 Sep 24;11(1):4837. doi: 10.1038/s41467-020-18607-1. PMID: 32973183; PMCID: PMC7515921.

Xie G, Ivica NA, Jia B, Li Y, Dong H, Liang Y, Brown D, Rizwan R, Chen J. CAR-T cells targeting a nucleophosmin neoepitope exhibit potent specific activity in mouse models of acute myeloid leukaemia. Nat Biomed Eng. 2020 Oct 12. doi: 10.1038/s41551-020-00625-5. Epub ahead of print. PMID: 33046866.

Kost-Alimova M, Sidhom EH, Satyam A, Chamberlain BT, Dvela-Levitt M, Melanson M, Alper SL, Santos J, Gutierrez J, Subramanian A, Byrne PJ, Grinkevich E, Reyes-Bricio E, Kim C, Clark AR, Watts AJB, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A. A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury. Cell Rep Med. 2020 Oct 29;1(8):100137. doi: 10.1016/j.xcrm.2020.100137. PMID: 33294858; PMCID: PMC7691435

Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK. Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital. FASEB J. 2020 Aug 28. doi: 10.1096/fj.202001700RR. Epub ahead of print. PMID: 32856766; PMCID: PMC7461169.

Tostanoski LH, Wegmann F, Martinot AJ, Loos C, McMahan K, Mercado NB, Yu J, Chan CN, Bondoc S, Starke CE, Nekorchuk M, Busman-Sahay K, Piedra-Mora C, Wrijil LM, Ducat S, Custers J, Atyeo C, Fischinger S, Burke JS, Feldman J, Hauser BM, Caradonna TM, Bondzie EA, Dagotto G, Gebre MS, Jacob-Dolan C, Lin Z, Mahrokhian SH, Nampanya F, Nityanandam R, Pessaint L, Porto M, Ali V, Benetiene D, Tevi K, Andersen H, Lewis MG, Schmidt AG, Lauffenburger DA, Alter G, Estes JD, Schuitemaker H, Zahn R, Barouch DH. Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters. Nat Med. 2020 Sep 3. doi: 10.1038/s41591-020-1070-6. Epub ahead of print. PMID: 32884153. PMCID: PMC7671939.

Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF Jr, Pillai S; Massachusetts Consortium on Pathogen Readiness Specimen Working Group. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 Aug 19:S0092-8674(20)31067-9. doi: 10.1016/j.cell.2020.08.025. Epub ahead of print. PMID: 32877699; PMCID: PMC7437499.

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Howard TP, Roberts CWM. Partitioning of Chemotherapeutics into Nuclear Condensates-Opening the Door to New Approaches for Drug Development. Mol Cell. 2020 Aug 20;79(4):544-545. doi: 10.1016/j.molcel.2020.07.029. PMID: 32822580.

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Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, Feldman J, Muus C, Wadsworth MH 2nd, Kazer SW, Hughes TK, Doran B, Gatter GJ, Vukovic M, Taliaferro F, Mead BE, Guo Z, Wang JP, Gras D, Plaisant M, Ansari M, Angelidis I, Adler H, Sucre JMS, Taylor CJ, Lin B, Waghray A, Mitsialis V, Dwyer DF, Buchheit KM, Boyce JA, Barrett NA, Laidlaw TM, Carroll SL, Colonna L, Tkachev V, Peterson CW, Yu A, Zheng HB, Gideon HP, Winchell CG, Lin PL, Bingle CD, Snapper SB, Kropski JA, Theis FJ, Schiller HB, Zaragosi LE, Barbry P, Leslie A, Kiem HP, Flynn JL, Fortune SM, Berger B, Finberg RW, Kean LS, Garber M, Schmidt AG, Lingwood D, Shalek AK, Ordovas-Montanes J; HCA Lung Biological Network. Electronic address: lung-network@humancellatlas.org; HCA Lung Biological Network. SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell. 2020 May 28;181(5):1016-1035.e19. doi: 10.1016/j.cell.2020.04.035. Epub 2020 Apr 27. PMID: 32413319; PMCID: PMC7252096.

Kazer SW, Aicher TP, Muema DM, Carroll SL, Ordovas-Montanes J, Miao VN, Tu AA, Ziegler CGK, Nyquist SK, Wong EB, Ismail N, Dong M, Moodley A, Berger B, Love JC, Dong KL, Leslie A, Ndhlovu ZM, Ndung'u T, Walker BD, Shalek AK. Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection. Nat Med. 2020 Apr;26(4):511-518. doi: 10.1038/s41591-020-0799-2. Epub 2020 Mar 23. PMID: 32251406; PMCID: PMC7237067.

McBride MJ, Mashtalir N, Winter EB, Dao HT, Filipovski M, D'Avino AR, Seo HS, Umbreit NT, St Pierre R, Valencia AM, Qian K, Zullow HJ, Jaffe JD, Dhe-Paganon S, Muir TW, Kadoch C. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nat Struct Mol Biol. 2020 Sep;27(9):836-845. doi: 10.1038/s41594-020-0466-9. Epub 2020 Aug 3. PMID: 32747783.

 

2019

Abudayyeh OO, Gootenberg JS, Franklin B, Koob J, Kellner MJ, Ladha A, Joung J, Kirchgatterer P, Cox DBT, Zhang F. A cytosine deaminase for programmable single-base RNA editing. Science. 2019 Jul 26;365(6451):382-386. doi: 10.1126/science.aax7063. Epub 2019 Jul 11. PubMed PMID: 31296651.

Toepfer CN, Sharma A, Cicconet M, Garfinkel AC, Mücke M, Neyazi M, Willcox JAL, Agarwal R, Schmid M, Rao J, Ewoldt J, Pourquié O, Chopra A, Chen CS, Seidman JG, Seidman CE. SarcTrack. Circ Res. 2019 Apr 12;124(8):1172-1183. doi: 10.1161/CIRCRESAHA.118.314505. PubMed PMID: 30700234; PubMed Central PMCID: PMC6485312.

Zhang L, Zhang Y, Cai T, Ahuja Y, He Z, Ho YL, Beam A, Cho K, Carroll R, Denny J, Kohane I, Liao K, Cai T. Automated grouping of medical codes via multiview banded spectral clustering. J Biomed Inform. 2019 Dec;100:103322. doi: 10.1016/j.jbi.2019.103322. Epub 2019 Oct 28. PMID: 31672532; PMCID: PMC7261410.

Ng SR, Rideout WM 3rd, Akama-Garren EH, Bhutkar A, Mercer KL, Schenkel JM, Bronson RT, Jacks T. CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer. Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):513-521. doi: 10.1073/pnas.1821893117. Epub 2019 Dec 23. PMID: 31871154; PMCID: PMC6955235.

Bhashyam AR, Basilico M, Harris MB, Heng M. Reply to Letter to the Editor: Prescription Opioid Type and the Likelihood of Prolonged Opioid Use After Orthopaedic Surgery. J Am Acad Orthop Surg. 2019 Apr 16. doi: 10.5435/JAAOS-D-19-00114. [Epub ahead of print] PubMed PMID: 31008876

Schwartz AL, Basilico MF, Friedman JL. Lactates and Local Knowledge - A Parable of Teamwork. N Engl J Med. 2019 Apr 11;380(15):1392-1393. doi: 10.1056/NEJMp1815228. PubMed PMID: 30970185.

Bhashyam AR, Basilico M, Weaver MJ, Harris MB, Heng M. Using Historical Variation in Opioid Prescribing Immediately After Fracture Surgery to Guide Maximum Initial Prescriptions. J Orthop Trauma. 2019 Apr;33(4):e131-e136. doi: 10.1097/BOT.0000000000001392. PubMed PMID: 30570619; PubMed Central PMCID: PMC6599458.

Basilico M, Bhashyam AR, Harris MB, Heng M. Prescription Opioid Type and the Likelihood of Prolonged Opioid Use After Orthopaedic Surgery. J Am Acad Orthop Surg. 2019 May 1;27(9):e423-e429. doi: 10.5435/JAAOS-D-17-00663. PubMed PMID:30289795; PubMed Central PMCID: PMC6590520.

Basilico, M.F., Bhashyam A.R., Harrington, E., & Heng, M.. Initial Opioid Supply Influences Long-Term Use and Doctor Shopping: An Instrumental Variables Approach. Journal of the American College of Surgeons. 2018, Oct; 227(4): S151-S152

Basilico, M.F., Bhashyam A.R., Heng M.. Racial Bias in Initial Opioid Prescribing for Orthopaedic Trauma Patients. Journal of the
American College of Surgeons. 2018, Oct; 227(4): S160

Cote DJ, Bever AM, Wilson KM, Smith TR, Smith-Warner SA, Stampfer MJ. A prospective study of tea and coffee intake and risk of glioma. Int J Cancer. 2019 Jul 15. doi: 10.1002/ijc.32574. [Epub ahead of print] PubMed PMID: 31304976

Twomey EC, Ji Z, Wales TE, Bodnar NO, Ficarro SB, Marto JA, Engen JR, Rapoport TA. Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science. 2019 Aug 2;365(6452). pii: eaax1033. doi: 10.1126/science.aax1033. Epub 2019 Jun 27. PubMed PMID: 31249135.

Botelho, Alyssa. "The Insights of Radical Science in the CRISPR Gene-Editing Era: A History of Science for the People and the Cambridge Recombinant DNA Controversy." Science as Culture (June 2019): 1-30. DOI: 10.1080/09505431.2019.1623190

Watanabe A, McCarthy KR, Kuraoka M, Schmidt AG, Adachi Y, Onodera T, Tonouchi  K, Caradonna TM, Bajic G, Song S, McGee CE, Sempowski GD, Feng F, Urick P, Kepler TB, Takahashi Y, Harrison SC, Kelsoe G. Antibodies to a Conserved Influenza Head  Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 2019 May 16;177(5):1124-1135.e16. doi: 10.1016/j.cell.2019.03.048. PubMed PMID: 31100267;  PubMed Central PMCID: PMC6825805.

Menotti M, Ambrogio C, Cheong TC, Pighi C, Mota I, Cassel SH, Compagno M, Wang Q, Dall'Olio R, Minero VG, Poggio T, Sharma GG, Patrucco E, Mastini C, Choudhari  R, Pich A, Zamo A, Piva R, Giliani S, Mologni L, Collings CK, Kadoch C, Gambacorti-Passerini C, Notarangelo LD, Anton IM, Voena C, Chiarle R. Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma. Nat Med. 2019 Jan;25(1):130-140. doi: 10.1038/s41591-018-0262-9. Epub 2018 Dec 3. PubMed PMID: 30510251; PubMed Central PMCID: PMC6556382.

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C. A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation. Nat Cell Biol. 2018 Dec;20(12):1410-1420. doi: 10.1038/s41556-018-0221-1. Epub 2018 Nov 5. PubMed PMID: 30397315; PubMed Central PMCID: PMC6698386.

Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, Eggan K. ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nat Neurosci. 2019 Feb;22(2):167-179. doi: 10.1038/s41593-018-0300-4. Epub 2019 Jan 14. PMID: 30643292; PMCID: PMC7153761.

Silva MA, Patel J, Kavouridis V, Gallerani T, Beers A, Chang K, Hoebel KV, Brown J, See AP, Gormley WB, Aziz-Sultan MA, Kalpathy-Cramer J, Arnaout O, Patel  NJ. Machine Learning Models can Detect Aneurysm Rupture and Identify Clinical Features Associated with Rupture. World Neurosurg. 2019 Nov;131:e46-e51. doi: 10.1016/j.wneu.2019.06.231. Epub 2019 Jul 9. PubMed PMID: 31295616.

Chang K, Beers AL, Bai HX, Brown JM, Ly KI, Li X, Senders JT, Kavouridis VK, Boaro A, Su C, Bi WL, Rapalino O, Liao W, Shen Q, Zhou H, Xiao B, Wang Y, Zhang PJ, Pinho MC, Wen PY, Batchelor TT, Boxerman JL, Arnaout O, Rosen BR, Gerstner ER, Yang L, Huang RY, Kalpathy-Cramer J. Automatic assessment of glioma burden: a deep learning algorithm for fully automated volumetric and bidimensional measurement. Neuro Oncol. 2019 Nov 4;21(11):1412-1422. doi: 10.1093/neuonc/noz106. PubMed PMID: 31190077.

Choudhery S, Chou SS, Chang K, Kalpathy-Cramer J, Lehman CD. Kinetic Analysis of Lesions Identified on a Rapid Abridged Multiphase (RAMP) Breast MRI Protocol. Acad Radiol. 2019 May 27. pii: S1076-6332(19)30222-3. doi: 10.1016/j.acra.2019.05.001. [Epub ahead of print] PubMed PMID: 31147233.

Coyner, A.S., Swan, R., Campbell, J.P., Ostmo, S., Brown, J.M., Kalpathy-Cramer, J., Kim, S.J., Jonas, K.E., Chan, R.P., Chiang, M.F. and Imaging and Informatics in Retinopathy of Prematurity Research Consortium (Chang, K.), 2019. Automated fundus image quality assessment in retinopathy of prematurity using deep convolutional neural networks. Ophthalmology Retina, 3(5), pp.444-450. DOI: 10.1016/j.oret.2019.01.015 PMID: 31044738

Chen, L., Madubuonwu, J., Pecos-Duarte, C., & Sommers, B. D. (2019, September 3). Medicaid Expansion in Texas: Economic & Employment Implications. The Commonwealth Fund.

Madubuonwu, J., Chen, L., & Sommers, B. D. (2019, September 27). Work Requirements in Kentucky Medicaid: A Policy in Limbo. The Commonwealth Fund. https://doi.org/10.26099/wm0z-p823

Chi D, Singhal H, Li L, Xiao T, Liu W, Pun M, Jeselsohn R, He H, Lim E, Vadhi R, Rao P, Long H, Garber J, Brown M. Estrogen receptor signaling is reprogrammed during breast tumorigenesis. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11437-11443. doi: 10.1073/pnas.1819155116. Epub 2019 May 20. PMID: 31110002; PMCID: PMC6561257.

Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K,  Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG. Transcriptional  States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Rep. 2019 Jun 11;27(11):3228-3240.e7. doi: 10.1016/j.celrep.2019.05.046. PubMed PMID:  31189107; PubMed Central PMCID: PMC6579117.

Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DEWeiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Subsets of exhausted CD8(+) T cells differentially mediate tumor control and respond to checkpoint blockade. Nat Immunol. 2019 Mar;20(3):326-336. doi: 10.1038/s41590-019-0312-6. Epub 2019 Feb 18. Erratum in: Nat Immunol. 2019 Oct 3;:. PubMed PMID: 30778252; PubMed Central  PMCID: PMC6673650.

Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, Barrett L, Dhe-Paganon S, Woolf CJ, Muir TW, Kadoch C. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 2019 Nov 27;179(6):1342-1356.e23. doi: 10.1016/j.cell.2019.10.044. Epub 2019 Nov 20. PMID: 31759698; PMCID: PMC7175411.

Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DE, Weiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Author Correction: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. Nat Immunol. 2019 Nov;20(11):1556. doi: 10.1038/s41590-019-0528-5. Erratum for: Nat Immunol. 2019 Mar;20(3):326-336. PMID: 31582823; PMCID: PMC7461603.

Connor Y, Tekleab Y, Tekleab S, Nandakumar S, Bharat D, Sengupta S. A mathematical model of tumor-endothelial interactions in a 3D co-culture. Sci Rep. 2019 Jun 10;9(1):8429. doi: 10.1038/s41598-019-44713-2. PMID: 31182723; PMCID: PMC6557844.

Giantini Larsen AM, Cote DJ, Zaidi HA, Bi WL, Schmitt PJ, Iorgulescu JB, Miller MB, Smith TR, Lopes MB, Jane JA, Laws ER. Spindle cell oncocytoma of the pituitary gland. J Neurosurg. 2018 Oct 19:1-9. doi: 10.3171/2018.4.JNS18211. [Epub ahead of print] PubMed PMID: 30485213; PubMed Central PMCID: PMC6486883.

Cote DJ, Bever AM, Wilson KM, Smith TR, Smith-Warner SA, Stampfer MJ. A prospective study of tea and coffee intake and risk of glioma. Int J Cancer. 2019 Jul 15. doi: 10.1002/ijc.32574. [Epub ahead of print] PubMed PMID: 31304976

Riordan CP, Storey A, Cote DJ, Smith ER, Scott RM. Results of more than 20 years of follow-up in pediatric patients with moyamoya disease undergoing pial synangiosis. J Neurosurg Pediatr. 2019 Mar 1:1-7. doi: 10.3171/2019.1.PEDS18457. [Epub ahead of print] PubMed PMID: 30835683.

Cote DJ, Barnett I, Onnela JP, Smith TR. Digital Phenotyping in Patients with Spine Disease: A Novel Approach to Quantifying Mobility and Quality of Life. World Neurosurg. 2019 Jun;126:e241-e249. doi: 10.1016/j.wneu.2019.01.297. Epub 2019 Feb 22. PubMed PMID: 30797933; PubMed Central PMCID: PMC6706326.

Senders JT, Karhade AV, Cote DJ, Mehrtash A, Lamba N, DiRisio A, Muskens IS, Gormley WB, Smith TR, Broekman MLD, Arnaout O. Natural Language Processing for Automated Quantification of Brain Metastases Reported in Free-Text Radiology Reports. JCO Clin Cancer Inform. 2019 Apr;3:1-9. doi: 10.1200/CCI.18.00138. PubMed PMID: 31002562.

Rubin DB, Danish HH, Ali AB, Li K, LaRose S, Monk AD, Cote DJ, Spendley L, Kim AH, Robertson MS, Torre M, Smith TR, Izzy S, Jacobson CA, Lee JW, Vaitkevicius H. Neurological toxicities associated with chimeric antigen receptor T-cell therapy. Brain. 2019 May 1;142(5):1334-1348. doi: 10.1093/brain/awz053. PubMed PMID: 30891590.

Cote DJ, Dasenbrock HH, Gormley WB, Smith TR, Dunn IF. Adverse Events After Microvascular Decompression: A National Surgical Quality Improvement Program Analysis. World Neurosurg. 2019 Aug;128:e884-e894. doi: 10.1016/j.wneu.2019.05.022. Epub 2019 May 11. PubMed PMID: 31082546; PubMed Central PMCID: PMC6825526.

Cote DJ, Ostrom QT, Gittleman H, Duncan KR, CreveCoeur TS, Kruchko C, Smith TR, Stampfer MJ, Barnholtz-Sloan JS. Glioma incidence and survival variations by county-level socioeconomic measures. Cancer. 2019 Oct 1;125(19):3390-3400. doi: 10.1002/cncr.32328. Epub 2019 Jun 17. PubMed PMID: 31206646; PubMed Central PMCID: PMC6744292.

Scott KW, Callahan DG, Chen JJ, Lynn MH, Cote DJ, Morenz A, Fisher J, Antoine VL, Lemoine ER, Bakshi SK, Stuart J, Hundert EM, Chang BS, Gooding H. Fostering Student-Faculty Partnerships for Continuous Curricular Improvement in Undergraduate Medical Education. Acad Med. 2019 Jul;94(7):996-1001. doi: 10.1097/ACM.0000000000002726. PubMed PMID: 30920449.

Ostrom QT, Fahmideh MA, Cote DJ, Muskens IS, Schraw JM, Scheurer ME, Bondy ML. Risk factors for childhood and adult primary brain tumors. Neuro Oncol. 2019 Nov  4;21(11):1357-1375. doi: 10.1093/neuonc/noz123. PubMed PMID: 31301133

Senders JT, Staples P, Mehrtash A, Cote DJ, Taphoorn MJB, Reardon DA, Gormley  WB, Smith TR, Broekman ML, Arnaout O. An Online Calculator for the Prediction of  Survival in Glioblastoma Patients Using Classical Statistics and Machine Learning. Neurosurgery. 2019 Oct 5. pii: nyz403. doi: 10.1093/neuros/nyz403. [Epub ahead of print] PubMed PMID: 31586211.

Abudayyeh OO, Gootenberg JS, Franklin B, Koob J, Kellner MJ, Ladha A, Joung J, Kirchgatterer P, Cox DBT, Zhang F. A cytosine deaminase for programmable single-base RNA editing. Science. 2019 Jul 26;365(6451):382-386. doi: 10.1126/science.aax7063. Epub 2019 Jul 11. PubMed PMID: 31296651.

Gillis JE, Coxe DJ, Doench JG, Haining WN, Sharpe AH. A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system. Nat Commun. 2019 Apr  10;10(1):1668. doi: 10.1038/s41467-019-09656-2. PubMed PMID: 30971695; PubMed Central PMCID: PMC6458184.

Kwok SJJ, Martino N, Dannenberg PH, Yun SH. Multiplexed laser particles for spatially resolved single-cell analysis. Light Sci Appl. 2019 Aug 21;8:74. doi: 10.1038/s41377-019-0183-5. eCollection 2019. PubMed PMID: 31645920; PubMed Central PMCID: PMC6804532

D'Gama JD, Waldor MK. An 'i' for ingenuity. Nat Microbiol. 2019 Jul;4(7):1071-1072. doi: 10.1038/s41564-019-0490-x. PubMed PMID: 31222173.

D'Gama JD, Ma Z, Zhang H, Liu X, Fan H, Morris ERA, Cohen ND, Cywes-Bentley C, Pier GB, Waldor MK. A Conserved Streptococcal Virulence Regulator Controls the Expression of a Distinct Class of M-Like Proteins. MBio. 2019 Oct 22;10(5). pii: e02500-19. doi: 10.1128/mBio.02500-19. PubMed PMID: 31641092; PubMed Central PMCID: PMC6805998.

Hubbard TP, D'Gama JD, Billings G, Davis BM, Waldor MK. Unsupervised Learning  Approach for Comparing Multiple Transposon Insertion Sequencing Studies. mSphere. 2019 Feb 20;4(1). pii: e00031-19. doi: 10.1128/mSphere.00031-19. PubMed PMID: 30787116; PubMed Central PMCID: PMC6382967.

Martino N, Kwok SJJ, Liapis AC, Forward S, Jang H, Kim HM, Wu SJ, Wu J, Dannenberg PH, Jang SJ, Lee YH, Yun SH. Wavelength-encoded laser particles for massively multiplexed cell tagging. Nat Photonics. 2019 Oct;13(10):720-727. doi: 10.1038/s41566-019-0489-0. Epub 2019 Jul 22. PMID: 32231707; PMCID: PMC7104740.

Ligorio M, Sil S, Malagon-Lopez J, Nieman LT, Misale S, Di Pilato M, Ebright RY, Karabacak MN, Kulkarni AS, Liu A, Vincent Jordan N, Franses JW, Philipp J, Kreuzer J, Desai N, Arora KS, Rajurkar M, Horwitz E, Neyaz A, Tai E, Magnus NKC, Vo KD, Yashaswini CN, Marangoni F, Boukhali M, Fatherree JP, Damon LJ, Xega K, Desai R, Choz M, Bersani F, Langenbucher A, Thapar V, Morris R, Wellner UF, Schilling O, Lawrence MS, Liss AS, Rivera MN, Deshpande V, Benes CH, Maheswaran S, Haber DA, Fernandez-Del-Castillo C, Ferrone CR, Haas W, Aryee MJ, Ting DT. Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell. 2019 Jun 27;178(1):160-175.e27. doi: 10.1016/j.cell.2019.05.012. Epub 2019 May 30. PubMed PMID: 31155233; PubMed Central PMCID: PMC6697165.

Cohen DT, Zhang C, Fadzen CM, Mijalis AJ, Hie L, Johnson KD, Shriver Z, Plante O, Miller SJ, Buchwald SL, Pentelute BL. A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins. Nat Chem. 2019 Jan;11(1):78-85. doi: 10.1038/s41557-018-0154-0. Epub 2018 Nov 5. PubMed PMID: 30397320; PubMed Central PMCID: PMC6454892.

Fadzen CM, Holden RL, Wolfe JM, Choo ZN, Schissel CK, Yao M, Hanson GJ, Pentelute BL. Chimeras of Cell-Penetrating Peptides Demonstrate Synergistic Improvement in Antisense Efficacy. Biochemistry. 2019 Sep 24;58(38):3980-3989. doi: 10.1021/acs.biochem.9b00413. Epub 2019 Sep 6. PubMed PMID: 31450889.

Sperling AS, Burgess M, Keshishian H, Gasser JA, Bhatt S, Jan M, SÅ‚abicki M, Sellar RS, Fink EC, Miller PG, Liddicoat BJ, Sievers QL, Sharma R, Adams DN, Olesinski EA, Fulciniti M, Udeshi ND, Kuhn E, Letai A, Munshi NC, Carr SA, Ebert BL. Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs. Blood. 2019 Jul 11;134(2):160-170. doi: 10.1182/blood.2019000789. Epub 2019 May 1. PMID: 31043423; PMCID: PMC6624968.

Lipnick SL, Agniel DM, Aggarwal R, Makhortova NR, Finlayson SG, Brocato A, Palmer N, Darras BT, Kohane I, Rubin LL. Systemic nature of spinal muscular atrophy revealed by studying insurance claims. PLoS One. 2019 Mar 14;14(3):e0213680. doi: 10.1371/journal.pone.0213680. PMID: 30870495; PMCID: PMC6417721.

Beaulieu-Jones B, Finlayson SG, Chivers C, Chen I, McDermott M, Kandola J, Dalca AV, Beam A, Fiterau M, Naumann T. Trends and Focus of Machine Learning Applications for Health Research. JAMA Netw Open. 2019 Oct 2;2(10):e1914051. doi: 10.1001/jamanetworkopen.2019.14051. PMID: 31651969; PMCID: PMC6822089.

Beaulieu-Jones BK, Finlayson SG, Yuan W, Altman RB, Kohane IS, Prasad V, Yu KH. Examining the Use of Real-World Evidence in the Regulatory Process. Clin Pharmacol Ther. 2019 Sep 28;10.1002/cpt.1658. doi: 10.1002/cpt.1658. [Epub ahead of print]. PMID: 31562770.

Vinyard ME, Su C, Siegenfeld AP, Waterbury AL, Freedy AM, Gosavi PM, Park Y, Kwan EE, Senzer BD, Doench JG, Bauer DE, Pinello L, Liau BB. CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nat Chem Biol. 2019 May;15(5):529-539. doi: 10.1038/s41589-019-0263-0. Epub 2019 Apr 15. PMID: 30992567.

Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder SS, Ge P, Shi R, Kim EJ, Liu A, Kim D, Quintin S, Jiang H, Kumar M, Yun SP, Kam TI, Mao X, Lee Y, Swing DA, Tessarollo L, Ko HS, Dawson VL, Dawson TM. Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease. Brain. 2019 Aug 1;142(8):2380-2401. doi: 10.1093/brain/awz172. PMID: 31237944; PMCID: PMC6658849.

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Kotliar D, Veres A, Nagy MA, Tabrizi S, Hodis E, Melton DA, Sabeti PC. Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq. Elife. 2019 Jul 8;8:e43803. doi: 10.7554/eLife.43803. PMID: 31282856; PMCID: PMC6639075.

Gunner G, Cheadle L, Johnson KM, Ayata P, Badimon A, Mondo E, Nagy MA, Liu L, Bemiller SM, Kim KW, Lira SA, Lamb BT, Tapper AR, Ransohoff RM, Greenberg ME, Schaefer A, Schafer DP. Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling. Nat Neurosci. 2019 Jul;22(7):1075-1088. doi: 10.1038/s41593-019-0419-y. Epub 2019 Jun 17. PMID: 31209379; PMCID: PMC6596419.

Kotliar D, Veres A, Nagy MA, Tabrizi S, Hodis E, Melton DA, Sabeti PC. Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq. Elife. 2019 Jul 8;8. pii: e43803. doi: 10.7554/eLife.43803. [Epub ahead of print] PubMed PMID: 31282856.

Shinde V, Narasimhan VM, Rohland N, Mallick S, Mah M, Lipson M, Nakatsuka N, Adamski N, Broomandkhoshbacht N, Ferry M, Lawson AM, Michel M, Oppenheimer J, Stewardson K, Jadhav N, Kim YJ, Chatterjee M, Munshi A, Panyam A, Waghmare P, Yadav Y, Patel H, Kaushik A, Thangaraj K, Meyer M, Patterson N, Rai N, Reich D. An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers. Cell. 2019 Oct 17;179(3):729-735.e10. doi: 10.1016/j.cell.2019.08.048. Epub 2019 Sep 5. PMID: 31495572; PMCID: PMC6800651.

Narasimhan VM, Patterson N, Moorjani P, Rohland N, Bernardos R, Mallick S, Lazaridis I, Nakatsuka N, Olalde I, Lipson M, Kim AM, Olivieri LM, Coppa A, Vidale M, Mallory J, Moiseyev V, Kitov E, Monge J, Adamski N, Alex N, Broomandkhoshbacht N, Candilio F, Callan K, Cheronet O, Culleton BJ, Ferry M, Fernandes D, Freilich S, Gamarra B, Gaudio D, Hajdinjak M, Harney É, Harper TK, Keating D, Lawson AM, Mah M, Mandl K, Michel M, Novak M, Oppenheimer J, Rai N, Sirak K, Slon V, Stewardson K, Zalzala F, Zhang Z, Akhatov G, Bagashev AN, Bagnera A, Baitanayev B, Bendezu-Sarmiento J, Bissembaev AA, Bonora GL, Chargynov TT, Chikisheva T, Dashkovskiy PK, Derevianko A, DobeÅ¡ M, Douka K, Dubova N, Duisengali MN, Enshin D, Epimakhov A, Fribus AV, Fuller D, Goryachev A, Gromov A, Grushin SP, Hanks B, Judd M, Kazizov E, Khokhlov A, Krygin AP, Kupriyanova E, Kuznetsov P, Luiselli D, Maksudov F, Mamedov AM, Mamirov TB, Meiklejohn C, Merrett DC, Micheli R, Mochalov O, Mustafokulov S, Nayak A, Pettener D, Potts R, Razhev D, Rykun M, Sarno S, Savenkova TM, Sikhymbaeva K, Slepchenko SM, Soltobaev OA, Stepanova N, Svyatko S, Tabaldiev K, Teschler-Nicola M, Tishkin AA, Tkachev VV, Vasilyev S, Velemínský P, Voyakin D, Yermolayeva A, Zahir M, Zubkov VS, Zubova A, Shinde VS, Lalueza-Fox C, Meyer M, Anthony D, Boivin N, Thangaraj K, Kennett DJ, Frachetti M, Pinhasi R, Reich D. The formation of human populations in South and Central Asia. Science. 2019 Sep 6;365(6457):eaat7487. doi: 10.1126/science.aat7487. PMID: 31488661; PMCID: PMC6822619.

Neel DV, Shulman DS, DuBois SG. Timing of first-in-child trials of FDA-approved oncology drugs. Eur J Cancer. 2019 May;112:49-56. doi: 10.1016/j.ejca.2019.02.011. Epub 2019 Mar 28. PMID: 30928805; PMCID: PMC6491224.

Netravali IA, Cariappa A, Yates K, Haining WN, Bertocchi A, Allard-Chamard H, Rosenberg I, Pillai S. 9-O-acetyl sialic acid levels identify committed progenitors of plasmacytoid dendritic cells. Glycobiology. 2019 Nov 20;29(12):861-875. doi: 10.1093/glycob/cwz062. PMID: 31411667; PMCID: PMC6861835.

Nwanaji-Enwerem JC, Bernier D, Lipsitz MC. Bedside Cardiac Ultrasound: Suprasternal Notch View-Detected Pulmonary Artery Clot in Transit. J Emerg Med. 2019 Dec 3;S0736-4679(19)30842-X. doi: 10.1016/j.jemermed.2019.10.010. [Epub ahead of print]. PMID: 31810833.

Nwanaji-Enwerem JC, Bernier D, Harris OM. Elderly Man with Post Myocardial Infarction Fatigue. J Emerg Med. 2019 Sep;57(3):395-396. doi: 10.1016/j.jemermed.2019.06.041. Epub 2019 Aug 12. PMID: 31416652.

Gao X, Colicino E, Shen J, Just AC, Nwanaji-Enwerem JC, Coull B, Lin X, Vokonas P, Zheng Y, Hou L, Schwartz J, Baccarelli AA. Correction for: Accelerated DNA methylation age and the use of antihypertensive medication among older adults. Aging (Albany NY). 2019 May 15;11(9):2911. doi: 10.18632/aging.101980. Erratum for: Aging (Albany NY). 2018 Nov 10;10(11):3210-3228. PMID: 31102506; PMCID: PMC6535072.

Gao X, Colicino E, Shen J, Kioumourtzoglou MA, Just AC, Nwanaji-Enwerem JC, Coull B, Lin X, Vokonas P, Zheng Y, Hou L, Schwartz J, Baccarelli AA. Impacts of air pollution, temperature, and relative humidity on leukocyte distribution: An epigenetic perspective. Environ Int. 2019 May;126:395-405. doi: 10.1016/j.envint.2019.02.053. Epub 2019 Feb 28. PMID: 30826618; PMCID: PMC6441628.

Gao X, Colicino E, Shen J, Just AC, Nwanaji-Enwerem JC, Wang C, Coull B, Lin X, Vokonas P, Zheng Y, Hou L, Schwartz J, Baccarelli AA. Comparative validation of an epigenetic mortality risk score with three aging biomarkers for predicting mortality risks among older adult males. Int J Epidemiol. 2019 Apr 30;dyz082. doi: 10.1093/ije/dyz082. [Epub ahead of print]. PMID: 31038702.

Nwanaji-Enwerem JC, Cardenas A, Chai PR, Weisskopf MG, Baccarelli AA, Boyer EW. Relationships of Long-Term Smoking and Moist Snuff Consumption With a DNA Methylation Age Relevant Smoking Index: An Analysis in Buccal Cells. Nicotine Tob Res. 2019 Aug 19;21(9):1267-1273. doi: 10.1093/ntr/nty156. PMID: 30053132; PMCID: PMC6941707.

Schaefer K, Owens TW, Page JE, Santiago M, Kahne D, Walker S. Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization. Nat Microbiol. 2020 Nov 9. doi: 10.1038/s41564-020-00808-5. Epub ahead of print. PMID: 33168989.

Chang CY, Abujaber S, Pany MJ, Obermeyer Z. Are vital sign abnormalities associated with poor outcomes after emergency department discharge? Acute Med. 2019;18(2):88-95. PMID: 31127797.

Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ. 2019. Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. Jan 11;10(1):168. doi: 10.1038/s41467-018-08127-4. PMID: 30635573

Wojtaszek JL, Chatterjee N, Najeeb J, Ramos A, Lee M, Bian K, Xue JY, Fenton BA, Park H, Li D, Hemann MT, Hong J, Walker GC, Zhou P. A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy. Cell. 2019 Jun 27;178(1):152-159.e11. doi: 10.1016/j.cell.2019.05.028. Epub 2019 Jun 6. PMID: 31178121; PMCID: PMC6644000.

Raoof S, Mulford IJ, Frisco-Cabanos H, Nangia V, Timonina D, Labrot E, Hafeez N, Bilton SJ, Drier Y, Ji F, Greenberg M, Williams A, Kattermann K, Damon L, Sovath S, Rakiec DP, Korn JM, Ruddy DA, Benes CH, Hammerman PS, Piotrowska Z, Sequist LV, Niederst MJ, Barretina J, Engelman JA, Hata AN. Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer. Oncogene. 2019 Sep;38(37):6399-6413. doi: 10.1038/s41388-019-0887-2. Epub 2019 Jul 19. PMID: 31324888; PMCID: PMC6742540.

Raoof S, Deng F, Cusack J. Abdomen distended by 31 L of cerebrospinal fluid: a peritoneal pseudocyst around a ventriculoperitoneal shunt. Lancet. 2019 Dec 7;394(10214):2118. doi: 10.1016/S0140-6736(19)32683-2. PMID: 31818411.

Zhang Y, Zhou CK, Rencsok EM, Fall K, Lotan TL, Loda M, Giunchi F, Platz EA, De Marzo AM, Mucci LA, Fiorentino M, Ebot EM. A Prospective Study of Intraprostatic Inflammation, Focal Atrophy, and Progression to Lethal Prostate Cancer. Cancer Epidemiol Biomarkers Prev. 2019 Dec;28(12):2047-2054. doi: 10.1158/1055-9965.EPI-19-0713. Epub 2019 Sep 18. PMID: 31533941.

Galinsky KJ, Reshef YA, Finucane HK, Loh PR, Zaitlen N, Patterson NJ, Brown BC, Price AL. Estimating cross-population genetic correlations of causal effect sizes. Genet Epidemiol. 2019 Mar;43(2):180-188. doi: 10.1002/gepi.22173. Epub 2018 Nov 25. PMID: 30474154; PMCID: PMC6375794.

van de Geijn B, Finucane H, Gazal S, Hormozdiari F, Amariuta T, Liu X, Gusev A, Loh PR, Reshef Y, Kichaev G, Raychauduri S, Price AL. Annotations capturing cell-type-specific TF binding explain a large fraction of disease heritability. Hum Mol Genet. 2019 Oct 9;ddz226. doi: 10.1093/hmg/ddz226. [Epub ahead of print]. PMID: 31595288.

Abuelezam NN, Reshef YA, Novak D, Grad YH, Seage Iii GR, Mayer K, Lipsitch M. Interaction Patterns of Men Who Have Sex With Men on a Geosocial Networking Mobile App in Seven United States Metropolitan Areas: Observational Study. J Med Internet Res. 2019 Sep 12;21(9):e13766. doi: 10.2196/13766. PMID: 31516124; PMCID: PMC6746104.

Bohrson CL, Barton AR, Lodato MA, Rodin RE, Luquette LJ, Viswanadham VV, Gulhan DC, Cortés-Ciriano I, Sherman MA, Kwon M, Coulter ME, Galor A, Walsh CA, Park PJ. Linked-read analysis identifies mutations in single-cell DNA-sequencing data. Nat Genet. 2019 Apr;51(4):749-754. doi: 10.1038/s41588-019-0366-2. Epub 2019 Mar 18. PMID: 30886424; PMCID: PMC6900933.

To TL, Cuadros AM, Shah H, Hung WHW, Li Y, Kim SH, Rubin DHF, Boe RH, Rath S, Eaton JK, Piccioni F, Goodale A, Kalani Z, Doench JG, Root DE, Schreiber SL, Vafai SB, Mootha VK. A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering. Cell. 2019 Nov 14;179(5):1222-1238.e17. doi: 10.1016/j.cell.2019.10.032. PMID: 31730859.

Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nat Immunol. 2019 Nov;20(11):1481-1493. doi: 10.1038/s41590-019-0502-2. Epub 2019 Oct 14. PMID: 31611699; PMCID: PMC6858552.

Park JO, Tanner LB, Wei MH, Khana DB, Jacobson TB, Zhang Z, Rubin SA, Li SH, Higgins MB, Stevenson DM, Amador-Noguez D, Rabinowitz JD. Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nat Chem Biol. 2019 Oct;15(10):1001-1008. doi: 10.1038/s41589-019-0364-9. Epub 2019 Sep 23. PMID: 31548693.

Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, Kaushal D, Kwon DS. HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis. Cell Rep. 2019 Feb 5;26(6):1409-1418.e5. doi: 10.1016/j.celrep.2019.01.021. PMID: 30726727; PMCID: PMC6417097.

Flavahan WA, Drier Y, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD, Bernstein BE. Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs. Nature. 2019 Nov;575(7781):229-233. doi: 10.1038/s41586-019-1668-3. Epub 2019 Oct 16. PMID: 31666694; PMCID: PMC6913936.

Subramanian A*, Sidhom EH*, Emani M, Vernon K, Sahakian N, Zhou Y, Kost-Alimova M, Slyper M, Waldman J, Dionne D, Nguyen LT, Weins A, Marshall JL, Rosenblatt-Rosen O, Regev A, Greka A. Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation. Nat Commun. 2019 Nov 29;10(1):5462. doi: 10.1038/s41467-019-13382-0. PMID: 31784515; PMCID: PMC6884507.

Dvela-Levitt M, Kost-Alimova M, Emani M, Kohnert E, Thompson R, Sidhom EH, Rivadeneira A, Sahakian N, Roignot J, Papagregoriou G, Montesinos MS, Clark AR, McKinney D, Gutierrez J, Roth M, Ronco L, Elonga E, Carter TA, Gnirke A, Melanson M, Hartland K, Wieder N, Hsu JC, Deltas C, Hughey R, Bleyer AJ, Kmoch S, Živná M, BareÅ¡ova V, Kota S, Schlondorff J, Heiman M, Alper SL, Wagner F, Weins A, Golub TR, Lander ES, Greka A. Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 2019 Jul 25;178(3):521-535.e23. doi: 10.1016/j.cell.2019.07.002. PMID: 31348885.

Sperling AS, Burgess M, Keshishian H, Gasser JA, Bhatt S, Jan M, Słabicki M, Sellar RS, Fink EC, Miller PG, Liddicoat BJ, Sievers QL, Sharma R, Adams DN, Olesinski EA, Fulciniti M, Udeshi ND, Kuhn E, Letai A, Munshi NC, Carr SA, Ebert BL. Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs. Blood. 2019 Jul 11;134(2):160-170. doi: 10.1182/blood.2019000789. Epub 2019 May 1. PMID: 31043423; PMCID: PMC6624968.

Starkweather,C.K., Uchida,N.. (2019). Dopamine reward prediction errors: the interplay between experiments and theory In Gazzaniga,M. (Ed.), The Cognitive Neurosciences, 6th edition (pp. 577-588). Cambridge: MIT Press.

Schwartz AL, Basilico MF, Friedman JL. Lactates and Local Knowledge - A Parable of Teamwork. N Engl J Med. 2019 Apr 11;380(15):1392-1393. doi: 10.1056/NEJMp1815228. PubMed PMID: 30970185.

Beaulieu-Laroche L, Toloza EHS, Brown NJ, Harnett MT. Widespread and Highly Correlated Somato-dendritic Activity in Cortical Layer 5 Neurons. Neuron. 2019 Jul 17;103(2):235-241.e4. doi: 10.1016/j.neuron.2019.05.014. Epub 2019 Jun 6. PMID: 31178115; PMCID: PMC6639136.

Shen K, Valenstein ML, Gu X, Sabatini DM. Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases. J Biol Chem. 2019 Feb 22;294(8):2970-2975. doi: 10.1074/jbc.AC119.007382. Epub 2019 Jan 16. PubMed PMID: 30651352; PubMed Central PMCID: PMC6393612.

Young JG, Vatsa R, Murray EJ, Hernán MA. Interval-cohort designs and bias in the estimation of per-protocol effects: a simulation study. Trials. 2019 Sep 5;20(1):552. doi: 10.1186/s13063-019-3577-z. PMID: 31488202; PMCID: PMC6729016.

Kotliar D*, Veres A*, Nagy MA, Tabrizi S, Hodis E, Melton DA, Sabeti PC. Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq. Elife. 2019 Jul 8;8:e43803. doi: 10.7554/eLife.43803. PMID: 31282856; PMCID: PMC6639075.

Taylor JL, Debost JPG, Morton SU, Wigdor EM, Heyne HO, Lal D, Howrigan DP, Bloemendal A, Larsen JT, Kosmicki JA, Weiner DJ, Homsy J, Seidman JG, Seidman CE, Agerbo E, McGrath JJ, Mortensen PB, Petersen L, Daly MJ, Robinson EB. Paternal-age-related de novo mutations and risk for five disorders. Nat Commun. 2019 Jul 10;10(1):3043. doi: 10.1038/s41467-019-11039-6. PMID: 31292440; PMCID: PMC6620346.

Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DE, Weiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. Nat Immunol. 2019 Mar;20(3):326-336. doi: 10.1038/s41590-019-0312-6. Epub 2019 Feb 18. Erratum in: Nat Immunol. 2019 Nov;20(11):1556. PMID: 30778252; PMCID: PMC6673650.

Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DE, Weiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Author Correction: Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. Nat Immunol. 2019 Nov;20(11):1556. doi: 10.1038/s41590-019-0528-5. Erratum for: Nat Immunol. 2019 Mar;20(3):326-336. PMID: 31582823.

LaFleur MW, Nguyen TH, Coxe MA, Yates KB, Trombley JD, Weiss SA, Brown FD, Gillis JE, Coxe DJ, Doench JG, Haining WN, Sharpe AH. A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system. Nat Commun. 2019 Apr 10;10(1):1668. doi: 10.1038/s41467-019-09656-2. PubMed PMID: 30971695; PubMed Central PMCID: PMC6458184.

Hwang WL, Wolfson RL, Niemierko A, Marcus KJ, DuBois SG, Haas-Kogan D. Clinical Impact of Tumor Mutational Burden in Neuroblastoma. J Natl Cancer Inst. 2019 Jul 1;111(7):695-699. doi: 10.1093/jnci/djy157. PMID: 30307503; PMCID: PMC6624164.

Yan WX, Hunnewell P, Alfonse LE, Carte JM, Keston-Smith E, Sothiselvam S, Garrity AJ, Chong S, Makarova KS, Koonin EV, Cheng DR, Scott DA. Functionally diverse type V CRISPR-Cas systems. Science. 2019 Jan 4;363(6422):88-91. doi: 10.1126/science.aav7271. Epub 2018 Dec 6. PMID: 3052307

Faure G, Shmakov SA, Yan WX, Cheng DR, Scott DA, Peters JE, Makarova KS, Koonin EV. CRISPR-Cas in mobile genetic elements: counter-defence and beyond. Nat Rev Microbiol. 2019 Aug;17(8):513-525. doi: 10.1038/s41579-019-0204-7. PMID: 31165781.7.

Ma L, Dichwalkar T, Chang JYH, Cossette B, Garafola D, Zhang AQ, Fichter M, Wang C, Liang S, Silva M, Kumari S, Mehta NK, Abraham W, Thai N, Li N, Wittrup KD, Irvine DJ. Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science. 2019 Jul 12;365(6449):162-168. doi: 10.1126/science.aav8692. PubMed PMID: 31296767.

Zhang Z, Gothe F, Pennamen P, James JR, McDonald D, Mata CP, Modis Y, Alazami AM, Acres M, Haller W, Bowen C, Döffinger R, Sinclair J, Brothers S, Zhang Y, Matthews HF, Naudion S, Pelluard F, Alajlan H, Yamazaki Y, Notarangelo LD, Thaventhiran JE, Engelhardt KR, Al-Mousa H, Hambleton S, Rooryck C, Smith KGC, Lenardo MJ. Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance. J Exp Med. 2019 Jun 3;216(6):1311-1327. doi: 10.1084/jem.20182304. Epub 2019 Apr 30. PMID: 31040185; PMCID: PMC6547869.

Ziegler CGK, Kim J, Piersanti K, Oyler-Yaniv A, Argyropoulos KV, van den Brink MRM, Palomba ML, Altan-Bonnet N, Altan-Bonnet G. Constitutive Activation of the B Cell Receptor Underlies Dysfunctional Signaling in Chronic Lymphocytic Leukemia. Cell Rep. 2019 Jul 23;28(4):923-937.e3. doi: 10.1016/j.celrep.2019.06.069. PMID: 31340154.

 

2018

Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A,  Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I,  Gehrke L, Zhang F, Sabeti PC. Field-deployable viral diagnostics using CRISPR-Cas13. Science. 2018 Apr 27;360(6387):444-448. doi: 10.1126/science.aas8836. PubMed PMID: 29700266.

Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F. Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6. Science. 2018 Apr 27;360(6387):439-444. doi: 10.1126/science.aaq0179. Epub  2018 Feb 15. PubMed PMID: 29449508; PubMed Central PMCID: PMC5961727.

Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. PubMed PMID: 30166441

Sharma A, Toepfer CN, Ward T, Wasson L, Agarwal R, Conner DA, Hu JH, Seidman CE. CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells. Curr Protoc Hum Genet. 2018 Jan 24;96:21.11.1-21.11.20. doi: 10.1002/cphg.52. PubMed PMID: 29364519; PubMed Central PMCID: PMC5785097.

Berne C, Ellison CK, Agarwal R, Severin GB, Fiebig A, Morton RI 3rd, Waters CM, Brun YV. Feedback regulation of Caulobacter crescentus holdfast synthesis by flagellum assembly via the holdfast inhibitor HfiA. Mol Microbiol. 2018 Oct;110(2):219-238. doi: 10.1111/mmi.14099. Epub 2018 Oct 5. PubMed PMID: 30079982; PubMed Central PMCID: PMC6195837.

Cai T, Zhang Y, Ho YL, Link N, Sun J, Huang J, Cai TA, Damrauer S, Ahuja Y, Honerlaw J, Huang J, Costa L, Schubert P, Hong C, Gagnon D, Sun YV, Gaziano JM, Wilson P, Cho K, Tsao P, O'Donnell CJ, Liao KP; VA Million Veteran Program. Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study. JAMA Cardiol. 2018 Sep 1;3(9):849-857. doi: 10.1001/jamacardio.2018.2287. PubMed PMID: 30090940.

Short FL, Akusobi C, Broadhurst WR, Salmond GPC. The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity. Sci Rep. 2018 Jan 17;8(1):1013. doi: 10.1038/s41598-017-18696-x. PubMed PMID: 29343718; PubMed Central PMCID: PMC5772629.

Allsop SA, Wichmann R, Mills F, Burgos-Robles A, Chang CJ, Felix-Ortiz AC, Vienne A, Beyeler A, Izadmehr EM, Glober G, Cum MI, Stergiadou J, Anandalingam KK, Farris K, Namburi P, Leppla CA, Weddington JC, Nieh EH, Smith AC, Ba D, Brown EN, Tye KM. Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. Cell. 2018 May 31;173(6):1329-1342.e18. doi: 10.1016/j.cell.2018.04.004. Epub 2018 May 3. PubMed PMID: 29731170.

Zhang Y, Malem-Shinitski N, Allsop SA, M Tye K, Ba D. Estimating a Separably Markov Random Field from Binary Observations. Neural Comput. 2018 Apr;30(4):1046-1079. doi: 10.1162/neco_a_01059. Epub 2018 Jan 30. PubMed PMID: 29381446.

Matthew Basilico, Abhiram Bhashyam, Emma Harrington, Marilyn Heng. Initial Opioid Supply Influences Long-Term Use and Doctor Shopping: An Instrumental Variables Approach, American College of Surgeons Clinical Congress. Boston, MA October 2018. Winner: Excellence in Research Award (Health Policy).

Matthew Basilico, Abhiram Bhashyam, Marilyn Heng. Racial bias in initial opioid prescribing for orthopaedic trauma patients. Boston, MA October 2018.

Abhiram Bhashyam, Matthew Basilico, Michael Weaver, Mitchel Harris, Marilyn Heng. An analysis of initial post-operative opioid prescribing patterns in orthopaedic trauma and a technique to determine prescribing guidelines. American Academy of Orthopaedic Surgeons Annual Meeting. 2018

Matthew Basilico, Abhiram R. Bhashyam, Mitchel Harris, Marilyn Heng. Prescription opioid type is not associated with increased risk of long-term use in opiate naïve patients after orthopaedic surgery. Accepted ASSH 2018.

Bhashyam AR, Basilico M, Weaver MJ, Harris MB, Heng M. Using historical variation in opioid prescribing immediately after fracture surgery to guide maximum initial prescriptions. J Orthop Trauma. 2018 Dec 12. doi: 10.1097/BOT.0000000000001392. [Epub ahead of print] PubMed PMID: 30570619.

Basilico M, Bhashyam AR, Harris MB, Heng M. Prescription Opioid Type and the Likelihood of Prolonged Opioid Use After Orthopaedic Surgery. J Am Acad Orthop Surg. 2018 Oct 4. doi: 10.5435/JAAOS-D-17-00663. [Epub ahead of print] PubMed PMID: 30289795.

Baum, M. L., Savulescu, J., Singh, I. in press. Chapter 5: A New Ethics For 21st Century Psychiatry. In: Geddes, J., Andreasen, N., and Goodwin, G. (eds). New Oxford Textbook of Psychiatry (3rd edition).

Saunders A, Macosko EZ, Wysoker A, Goldman M, Krienen FM, de Rivera H, Bien E,, Baum M, Bortolin L, Wang S, Goeva A, Nemesh J, Kamitaki N, Brumbaugh S, Kulp D, McCarroll SA. Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain. Cell. 2018 Aug 9;174(4):1015-1030.e16. doi: 10.1016/j.cell.2018.07.028. PubMed PMID: 30096299; PubMed Central PMCID:
PMC6447408.

Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA. Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nat Struct Mol Biol. 2018 Jul;25(7):616-622. doi: 10.1038/s41594-018-0085-x. Epub 2018 Jul 2. PubMed PMID: 29967539; PubMed Central PMCID: PMC6044470.

Schmalzer, Sigrid, Daniel S. Chard, and Alyssa Botelho, eds. Science for the People: Documents from America's Movement of Radical Scientists, 1969-1989. Amherst, MA: University of Massachusetts Press, 2018.

Botelho, Alyssa. "Biology and Medicine." In Science for the People: Documents from America's Movement of Radical Scientists, 1969-1989, edited by Sigrid Schmalzer, Daniel S. Chard, and Alyssa Botelho. Amherst, MA: University of Massachusetts Press, 2018.

Botelho, Alyssa. "Race and Gender." In Science for the People: Documents from America's Movement of Radical Scientists, 1969-1989, edited by Sigrid Schmalzer, Daniel S. Chard, and Alyssa Botelho. Amherst, MA: University of Massachusetts Press, 2018.

Pan J, Meyers RM, Michel BC, Mashtalir N, Sizemore AE, Wells JN, Cassel SH, Vazquez F, Weir BA, Hahn WC, Marsh JA, Tsherniak A, Kadoch C. Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale  Fitness Screens. Cell Syst. 2018 May 23;6(5):555-568.e7. doi: 10.1016/j.cels.2018.04.011. Epub 2018 May 16. PubMed PMID: 29778836.

Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch C. Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes. Cell. 2018 Oct 18. pii: S0092-8674(18)31244-3. doi: 10.1016/j.cell.2018.09.032. [Epub ahead of print] PubMed PMID: 30343899.

Brown JM, Campbell JP, Beers A, Chang K, Ostmo S, Chan RVP, Dy J, Erdogmus D, Ioannidis S, Kalpathy-Cramer J, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity (i-ROP) Research Consortium. Automated Diagnosis of Plus Disease in Retinopathy of Prematurity Using Deep Convolutional Neural Networks. JAMA Ophthalmol. 2018 May 2. doi: 10.1001/jamaophthalmol.2018.1934. [Epub ahead of print] PubMed PMID: 29801159.

Chang K, Balachandar N, Lam C, Yi D, Brown J, Beers A, Rosen B, Rubin DL, Kalpathy-Cramer J. Distributed deep learning networks among institutions for medical imaging. J Am Med Inform Assoc. 2018 Mar 29. doi: 10.1093/jamia/ocy017. [Epub ahead of print] PubMed PMID: 29617797.

Tang L, Deng L, Bai HX, Sun J, Neale N, Wu J, Wang Y, Chang K, Huang RY, Zhang PJ, Li X, Xiao B, Cao Y, Tao Y, Yang L. Reduced expression of DNA repair genes and chemosensitivity in 1p19q codeleted lower-grade gliomas. J Neurooncol. 2018 Jun 19. doi: 10.1007/s11060-018-2915-4. [Epub ahead of print] PubMed PMID: 29923053

Winzeck S, Hakim A, McKinley R, Pinto JAADSR, Alves V, Silva C, Pisov M, Krivov E, Belyaev M, Monteiro M, Oliveira A, Choi Y, Paik MC, Kwon Y, Lee H, Kim BJ, Won JH, Islam M, Ren H, Robben D, Suetens P, Gong E, Niu Y, Xu J, Pauly JM, Lucas C, Heinrich MP, Rivera LC, Castillo LS, Daza LA, Beers AL, Arbelaezs P, Maier O, Chang K, Brown JM, Kalpathy-Cramer J, Zaharchuk G, Wiest R, Reyes M. ISLES 2016 and 2017-Benchmarking Ischemic Stroke Lesion Outcome Prediction Based on Multispectral MRI. Front Neurol. 2018 Sep 13;9:679. doi: 10.3389/fneur.2018.00679. eCollection 2018. PubMed PMID: 30271370; PubMed Central PMCID: PMC6146088.

Tyssowski KM, DeStefino NR, Cho JH, Dunn CJ, Poston RG, Carty CE, Jones RD, Chang SM, Romeo P, Wurzelmann MK, Ward JM, Andermann ML, Saha RN, Dudek SM, Gray  JM. Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron. 2018 May 2;98(3):530-546.e11. doi: 10.1016/j.neuron.2018.04.001. Epub 2018 Apr 19. PubMed PMID: 29681534; PubMed Central PMCID: PMC5934296.

Lima Queiroz A, Zhang B, Comstock DE, Hao Y, Eriksson M, Hydbring P, Vakifahmetoglu-Norberg H, Norberg E. miR-126-5p targets Malate Dehydrogenase 1 in non-small cell lung carcinomas. Biochem Biophys Res Commun. 2018 May 5;499(2):314-320. doi: 10.1016/j.bbrc.2018.03.154. Epub 2018 Mar 26. PubMed PMID: 29574159.

DiRisio AC, Muskens IS, Cote DJ, Babu M, Gormley WB, Smith TR, Moojen WA, Broekman ML. Oversight and Ethical Regulation of Conflicts of Interest in Neurosurgery in the United States. Neurosurgery. 2018 May 30. doi: 10.1093/neuros/nyy227. [Epub ahead of print] PubMed PMID: 29850841.

Zaidi HA, Penn DL, Cote DJ, Laws ER Jr. Root cause analysis of diagnostic and  surgical failures in the treatment of suspected Cushing's disease. J Clin Neurosci. 2018 Jul;53:153-159. doi: 10.1016/j.jocn.2018.04.055. Epub 2018 Apr 30. PubMed PMID: 29716804.

Martin E, Muskens IS, Senders JT, Cote DJ, Smith TR, Broekman MLD. A nationwide analysis of 30-day adverse events, unplanned readmission, and length of hospital stay after peripheral nerve surgery in extremities and the brachial plexus. Microsurgery. 2018 Apr 15. doi: 10.1002/micr.30330. PubMed PMID: 29656387.

Zaki MM, Cote DJ, Muskens IS, Smith TR, Broekman ML. Defining Innovation in Neurosurgery: Results from an International Survey. World Neurosurg. 2018 Jun;114:e1038-e1048. doi: 10.1016/j.wneu.2018.03.142. Epub 2018 Mar 29. PubMed PMID: 29604357.

Alotaibi NM, Noormohamed N, Cote DJ, Alharthi S, Doucette J, Zaidi HA, Mekary  RA, Smith TR. Physiologic Growth Hormone-Replacement Therapy and Craniopharyngioma Recurrence in Pediatric Patients: A Meta-Analysis. World Neurosurg. 2018 Jan;109:487-496.e1. doi: 10.1016/j.wneu.2017.09.164. Epub 2017 Oct 4. Review. PubMed PMID: 28987837; PubMed Central PMCID: PMC5729106.

Senders JT, Goldhaber NH, Cote DJ, Muskens IS, Dawood HY, De Vos FYFL, Gormley WB, Smith TR, Broekman MLD. Venous thromboembolism and intracranial hemorrhage after craniotomy for primary malignant brain tumors: a National Surgical Quality  Improvement Program analysis. J Neurooncol. 2018 Jan;136(1):135-145. doi: 10.1007/s11060-017-2631-5. Epub 2017 Oct 16. PubMed PMID: 29039075; PubMed Central PMCID: PMC5754452.

Burke WT, Cote DJ, Iuliano SI, Zaidi HA, Laws ER. A practical method for prevention of readmission for symptomatic hyponatremia following transsphenoidal surgery. Pituitary. 2018 Feb;21(1):25-31. doi: 10.1007/s11102-017-0843-5. PubMed  PMID: 29075986.

Almutairi RD, Muskens IS, Cote DJ, Dijkman MD, Kavouridis VK, Crocker E, Ghazawi K, Broekman MLD, Smith TR, Mekary RA, Zaidi HA. Gross total resection of  pituitary adenomas after endoscopic vs. microscopic transsphenoidal surgery: a meta-analysis. Acta Neurochir (Wien). 2018 Jan 6. doi: 10.1007/s00701-017-3438-z. [Epub ahead of print] Review. PubMed PMID: 29307020.

Altuwaijri N, Cote DJ, Lamba N, Albenayan W, Ren SP, Zaghloul I, Doucette J, Zaidi HA, Mekary RA, Smith TR. Headache Resolution After Rathke Cleft Cyst Resection: A Meta-Analysis. World Neurosurg. 2018 Jan 5. pii: S1878-8750(18)30025-1. doi: 10.1016/j.wneu.2017.12.170. PubMed PMID: 29309984.

Alreshidi M, Cote DJ, Dasenbrock HH, Acosta M, Can A, Doucette J, Simjian T, Hulou MM, Wheeler LA, Huang K, Zaidi HA, Du R, Aziz-Sultan MA, Mekary RA, Smith TR. Coiling Versus Microsurgical Clipping in the Treatment of Unruptured Middle Cerebral Artery Aneurysms: A Meta-Analysis. Neurosurgery. 2018 Feb 9. doi: 10.1093/neuros/nyx623. PubMed PMID: 29438551.

Senders JT, Muskens IS, Cote DJ, Goldhaber NH, Dawood HY, Gormley WB, Broekman MLD, Smith TR. Thirty-Day Outcomes After Craniotomy for Primary Malignant Brain Tumors: A National Surgical Quality Improvement Program Analysis. Neurosurgery. 2018 Feb 22. doi: 10.1093/neuros/nyy001. PubMed PMID: 29481613.

Ostrom Q*, Cote DJ*, Ascha M, Kruchko C, Barnholtz-Sloan JS. "Patterns of adult glioma incidence and survival by race and ethnicity in the United States from 2000-2014." JAMA Oncology. 2018 Jun. PMID: 29931168; PubMed Central PMCID: PMC6143018.

Cote DJ, Downer MK, Smith TR, Smith-Warner SA, Egan KM, Stampfer MJ. Height, waist circumference, body mass index, and body somatotype across the life course  and risk of glioma. Cancer Causes Control. 2018 Aug;29(8):707-719. doi: 10.1007/s10552-018-1052-x. Epub 2018 Jun 26. PubMed PMID: 29943102.

Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, Schlaeger TM, Mochida GH, Hess H, Lee WA, Lehtinen MK, Kirchhausen T, Haussler D, Jacobs FMJ, Gaudin R, Walsh CA. The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Rep. 2018 Jul 24;24(4):973-986.e8. doi: 10.1016/j.celrep.2018.06.100. PMID: 30044992; PMCID: PMC6178983.

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

Tyssowski KM, DeStefino NR, Cho JH, Dunn CJ, Poston RG, Carty CE, Jones RD, Chang SM, Romeo P, Wurzelmann MK, Ward JM, Andermann ML, Saha RN, Dudek SM, Gray  JM. Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron. 2018 May 2;98(3):530-546.e11. doi: 10.1016/j.neuron.2018.04.001. Epub 2018 Apr 19. PubMed PMID: 29681534; PubMed Central PMCID: PMC5934296.

Fan X, Xie B, Zou J, Luo J, Qin Z, D'Gama AM, Shi J, Yi S, Yang Q, Wang J, Luo S, Chen S, Agrawal PB, Li Q, Shen Y. Novel ETFDH mutations in four cases of riboflavin responsive multiple acyl-CoA dehydrogenase deficiency. Mol Genet Metab Rep. 2018 Jun 11;16:15-19. doi: 10.1016/j.ymgmr.2018.05.007. eCollection 2018 Sep. PubMed PMID: 29988809; PubMed Central PMCID: PMC6031868.

Ching T, Himmelstein DS, Beaulieu-Jones BK, Kalinin AA, Do BT, Way GP, Ferrero E, Agapow PM, Zietz M, Hoffman MM, Xie W, Rosen GL, Lengerich BJ, Israeli J, Lanchantin J, Woloszynek S, Carpenter AE, Shrikumar A, Xu J, Cofer EM, Lavender CA, Turaga SC, Alexandari AM, Lu Z, Harris DJ, DeCaprio D, Qi Y, Kundaje A, Peng  Y, Wiley LK, Segler MHS, Boca SM, Swamidass SJ, Huang A, Gitter A, Greene CS. Opportunities and obstacles for deep learning in biology and medicine. J R Soc Interface. 2018 Apr;15(141). pii: 20170387. doi: 10.1098/rsif.2017.0387. Review.  PubMed PMID: 29618526; PubMed Central PMCID: PMC5938574.

Wutz A, Loonis R, Roy JE, Donoghue JA, Miller EK. Different Levels of Category Abstraction by Different Dynamics in Different Prefrontal Areas. Neuron. 2018 Feb 7;97(3):716-726.e8. doi: 10.1016/j.neuron.2018.01.009. Epub 2018 Jan 27. PubMed PMID: 29395915.

Dosumu-Johnson RT, Cocoran AE, Chang Y, Nattie E, Dymecki SM. Acute perturbation of Pet1-neuron activity in neonatal mice impairs cardiorespiratory homeostatic recovery. Elife. 2018 Oct 23;7. pii: e37857. doi: 10.7554/eLife.37857. PubMed PMID: 30350781.

Drosu NC, Edelman ER, Housman DE. Could antiretrovirals be treating EBV in MS? A case report. Mult Scler Relat Disord. 2018 May;22:19-21. doi: 10.1016/j.msard.2018.02.029. Epub 2018 Feb 27. PubMed PMID: 29510325.

Legler S, Celano CM, Amador A, Novis A, Ebrahim S, Huffman JC. Development and Theoretical Approach to an Adaptive Text Message Program to Promote Well-Being and Health Behaviors in Primary Care Patients. Prim Care Companion CNS Disord. 2018 Oct 25;20(5). pii: 18br02353. doi: 10.4088/PCC.18br02353. PubMed PMID: 30444962.

Jing J, d'Angremont E, Zafar S, Rosenthal ES, Tabaeizadeh M, Ebrahim S, Dauwels J, Westover MB. Rapid Annotation of Seizures and Interictal-ictal Continuum EEG Patterns. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3394-3397. doi: 10.1109/EMBC.2018.8513059. PubMed PMID: 30441116; PubMed Central PMCID: PMC6776236.

Wolfe JM, Fadzen CM, Choo ZN, Holden RL, Yao M, Hanson GJ, Pentelute BL. Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery. ACS Cent Sci. 2018 Apr 25;4(4):512-520. doi: 10.1021/acscentsci.8b00098. Epub 2018 Apr 5. PubMed PMID: 29721534; PubMed Central PMCID: PMC5920612.

Wolfe JM, Fadzen CM, Holden RL, Yao M, Hanson GJ, Pentelute BL. Perfluoroaryl  Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides. Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4756-4759. doi: 10.1002/anie.201801167. Epub 2018 Mar 14. PubMed PMID: 29479836.

Donovan KA, An J, Nowak RP, Yuan JC, Fink EC, Berry BC, Ebert BL, Fischer ES.  Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. Elife. 2018 Aug 1;7. pii: e38430. doi: 10.7554/eLife.38430. PubMed PMID: 30067223; PubMed Central PMCID: PMC6156078.

Fink EC, McConkey M, Adams DN, Haldar SD, Kennedy JA, Guirguis AA, Udeshi ND,  Mani DR, Chen M, Liddicoat B, Svinkina T, Nguyen AT, Carr SA, Ebert BL. Crbn (I391V) is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice. Blood. 2018 Oct 4;132(14):1535-1544. doi: 10.1182/blood-2018-05-852798. Epub 2018 Jul 31. PubMed PMID: 30064974; PubMed Central PMCID: PMC6172563.

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

Finlayson SG, Bowers JD, Ito J, Zittrain JL, Beam AL, Kohane IS. Adversarial attacks on medical machine learning. Science. 2019 Mar 22;363(6433):1287-1289. doi: 10.1126/science.aaw4399. PubMed PMID: 30898923.

Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC. An alternative splicing switch in FLNB  promotes the mesenchymal cell state in human breast cancer. Elife. 2018 Jul 30;7. pii: e37184. doi: 10.7554/eLife.37184. PubMed PMID: 30059005; PubMed Central PMCID: PMC6103745.

Anahtar MN, Gootenberg DB, Mitchell CM, Kwon DS. Cervicovaginal Microbiota and Reproductive Health: The Virtue of Simplicity. Cell Host Microbe. 2018 Feb 14;23(2):159-168. doi: 10.1016/j.chom.2018.01.013. Review. PubMed PMID: 29447695

Grossman SR, Engreitz J, Ray JP, Nguyen TH, Hacohen N, Lander ES. Positional specificity of different transcription factor classes within enhancers. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7222-E7230. doi: 10.1073/pnas.1804663115. Epub 2018 Jul 9. PMID: 29987030

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S,  Palamara PF, Pinello L, Patterson N, Adams RP, Price AL. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk. Nat Genet. 2018 Oct;50(10):1483-1493. doi: 10.1038/s41588-018-0196-7. Epub 2018 Sep 3. PubMed PMID: 30177862; PubMed Central PMCID: PMC6202062.

Peter F. Martelli, Tuna Cem Hayirli, (2018) "Three perspectives on evidence-based management: rank, fit, variety", Management Decision, Vol. 56 Issue: 10, pp.2085-2100, https://doi.org/10.1108/MD-09-2017-0920

Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J, Howard TP, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B,  Steelman S, Vazquez F, Tsherniak A, Aguirre AJ, Doench JG, Piccioni F, Roberts CWM, Meyerson M, Getz G, Johannessen CM, Root DE, Hahn WC. Mutational processes shape the landscape of TP53 mutations in human cancer. Nat Genet. 2018 Oct;50(10):1381-1387. doi: 10.1038/s41588-018-0204-y. Epub 2018 Sep 17. PubMed PMID: 30224644; PubMed Central PMCID: PMC6168352.

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M, Deb C, Wadsworth MH 2nd, Hughes TK, Kazer SW, Yoshimoto E, Cahill KN, Bhattacharyya N, Katz HR, Berger B, Laidlaw TM, Boyce JA, Barrett NA, Shalek AK. Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature. 2018 Aug;560(7720):649-654. doi: 10.1038/s41586-018-0449-8. Epub 2018 Aug 22. PubMed PMID: 30135581; PubMed Central PMCID: PMC6133715.

Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH 2nd, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol. 2018 Jun 5;16(1):62. doi: 10.1186/s12915-018-0527-2. PubMed PMID: 29871632; PubMed Central PMCID: PMC5989470.

Silver JN, Ashbaugh CD, Miles JJ, Wu H, Marecki GT, Hwang JK, Jiao JA, Abrams  M, Sullivan EJ, Wesemann DR. Deployment of Transchromosomal Bovine for Personalized Antimicrobial Therapy. Clin Infect Dis. 2018 Mar 19;66(7):1116-1119. doi: 10.1093/cid/cix977. PubMed PMID: 29272362.

Jayaraman D, Bae BI, Walsh CA. The Genetics of Primary Microcephaly. Annu Rev  Genomics Hum Genet. 2018 Aug 31;19:177-200. doi:10.1146/annurev-genom-083117-021441. Epub 2018 May 23. Review. PubMed PMID: 29799801

Stouffs K, Stergachis AB, Vanderhasselt T, Dica A, Janssens S, Vandervore L, Gheldof A, Bodamer O, Keymolen K, Seneca S, Liebaers I, Jayaraman D, Hill HE, Partlow JN, Walsh CA, Jansen AC. Expanding the clinical spectrum of biallelic ZNF335 variants. Clin Genet. 2018 Aug;94(2):246-251. doi: 10.1111/cge.13260. Epub 2018 May 3. PMID: 29652087; PMCID: PMC6361164.

Kalinich M, Haber DA. Cancer detection: Seeking signals in blood. Science. 2018 Feb 23;359(6378):866-867. doi: 10.1126/science.aas9102. PubMed PMID: 29472467.

Kwan TT, Bardia A, Spring LM, Giobbie-Hurder A, Kalinich M, Dubash T, Sundaresan T, Hong X, LiCausi JA, Ho U, Silva EJ, Wittner BS, Sequist LV, KapurR, Miyamoto DT, Toner M, Haber DA, Maheswaran S. A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer. Cancer Discov. 2018 Oct;8(10):1286-1299. doi: 10.1158/2159-8290.CD-18-0432. Epub 2018 Aug 13. PubMed PMID: 30104333; PubMed Central PMCID: PMC6170694.

Hong X, Sullivan RJ, Kalinich M, Kwan TT, Giobbie-Hurder A, Pan S, LiCausi JA, Milner JD, Nieman LT, Wittner BS, Ho U, Chen T, Kapur R, Lawrence DP, Flaherty KT, Sequist LV, Ramaswamy S, Miyamoto DT, Lawrence M, Toner M, Isselbacher KJ, Maheswaran S, Haber DA. Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2467-2472. doi: 10.1073/pnas.1719264115. Epub 2018 Feb 16. PubMed PMID: 29453278; PubMed Central PMCID: PMC5877960.

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting  DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA. An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer. Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4. PubMed PMID: 29301747.

Bhan I, Mosesso K, Goyal L, Philipp J, Kalinich M, Franses JW, Choz M, Oklu R, Toner M, Maheswaran S, Haber DA, Zhu AX, Chung RT, Aryee M, Ting DT. Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease. Gastroenterology. 2018 Dec;155(6):2016-2018.e11. doi: 10.1053/j.gastro.2018.09.020. Epub 2018 Sep 13. PubMed PMID: 30218669.

Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala  NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M. Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing. Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18. PubMed PMID: 29909985; PubMed Central PMCID: PMC6046279.

Knouse KA, Lopez KE, Bachofner M, Amon A. Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture. Cell. 2018 Sep 20;175(1):200-211.e13.
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