Publications

2013

Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F.Genome engineering using the CRISPR-Cas9 system. Nat Protoc. 2013 Nov;8(11):2281-308. doi: 10.1038/nprot.2013.143. Epub 2013 Oct 24. PMID: 24157548

Agarwala V, Flannick J, Sunyaev S; GoT2D Consortium, Altshuler D. Evaluating empirical bounds on complex disease genetic architecture. Nat Genet. 2013 Oct 20. doi: 10.1038/ng.2804. [Epub ahead of print] PMID: 24141362

Flannick J, Beer NL, Bick AG, Agarwala V, Molnes J, Gupta N, Burtt NP, Florez JC, Meigs JB, Taylor H, Lyssenko V, Irgens H, Fox E, Burslem F, Johansson S, Brosnan MJ, Trimmer JK, Newton-Cheh C, Tuomi T, Molven A, Wilson JG, O'Donnell CJ, Kathiresan S, Hirschhorn JN, Njølstad PR, Rolph T, Seidman JG, Gabriel S, Cox DR, Seidman CE, Groop L, Altshuler D. Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. Nat Genet. 2013 Oct 6. doi: 10.1038/ng.2794. [Epub ahead of print] PMID: 24097065

Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21. PMID: 23873081

Bojarski EF, Strauss AC, Fagin AP, Plantinga TS, Hoischen A, Veltman J, Allsop SA, Granadillo VJ, William A, Netea MG, Dimitrakoff J. Novel PI3Kγ mutation in a 44-year-old man with chronic infections and chronic pelvic pain. PLoS One. 2013 Jul 8;8(7):e68118. doi: 10.1371/journal.pone.0068118. Print 2013. PMID: 23861857

Auyeung VC, Ulitsky I, McGeary SE, Bartel DP. Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing.
Cell. 2013 Feb 14;152(4):844-58. doi: 10.1016/j.cell.2013.01.031.PMID: 23415231

Chatterjee P, Agyemang AF, Alimzhanov MB, Degn S, Tsiftsoglou SA, Alicot E, Jones SA, Ma M, Carroll MC. Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner. Eur J Immunol. 2013 Jun 10. doi: 10.1002/eji.201343412. [Epub ahead of print] PMID: 23749435

Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, Macdonald TY, Ghandi M, Van Allen E, Kryukov GV, Sboner A, Theurillat JP, Soong TD, Nickerson E, Auclair D, Tewari A, Beltran H, Onofrio RC, Boysen G, Guiducci C, Barbieri CE, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Ramos AH, Winckler W, Cipicchio M, Ardlie K, Kantoff PW, Berger MF, Gabriel SB, Golub TR, Meyerson M, Lander ES, Elemento O, Getz G, Demichelis F, Rubin MA, Garraway LA. Punctuated evolution of prostate cancer genomes.Cell. 2013 Apr 25;153(3):666-77. doi: 10.1016/j.cell.2013.03.021. PMID: 23622249.  NIHMS: NIHMS472000

Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, Ramos AH, Pugh TJ, Stransky N, Helman E, Kim J, Sougnez C, Ambrogio L, Nickerson E, Shefler E, Cortés ML, Auclair D, Saksena G, Voet D, Noble M, DiCara D, Lin P, Lichtenstein L, Heiman DI, Fennell T, Imielinski M, Hernandez B, Hodis E, Baca S, Dulak AM, Lohr J, Landau DA, Wu CJ, Melendez-Zajgla J, Hidalgo-Miranda A, Koren A, McCarroll SA, Mora J, Lee RS, Crompton B, Onofrio  R, Parkin M, Winckler W, Ardlie K, Gabriel SB, Roberts CW, Biegel JA, Stegmaier K, Bass AJ, Garraway LA, Meyerson M, Golub TR, Gordenin DA, Sunyaev S, Lander ES, Getz G. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013 Jul 11;499(7457):214-8. doi: 10.1038/nature12213. Epub 2013 Jun 16. PubMed PMID: 23770567; PubMed Central PMCID: PMC3919509.

Bagley AF, Hill S, Rogers GS, Bhatia SN. Plasmonic Photothermal Heating of Intraperitoneal Tumors through the Use of an Implanted Near-Infrared Source. ACS Nano. 2013 Aug 20. PMID: 23961973

Flannick J, Beer NL, Bick AG, Agarwala V, Molnes J, Gupta N, Burtt NP, Florez JC, Meigs JB, Taylor H, Lyssenko V, Irgens H, Fox E, Burslem F, Johansson S, Brosnan MJ, Trimmer JK, Newton-Cheh C, Tuomi T, Molven A, Wilson JG, O'Donnell CJ, Kathiresan S, Hirschhorn JN, Njølstad PR, Rolph T, Seidman JG, Gabriel S, Cox DR, Seidman CE, Groop L, Altshuler D. Nat Genet. 2013 Oct 6. doi: 10.1038/ng.2794. [Epub ahead of print] PMID:24097065

Rosso C, Buckland DM, Polzer C, Sadoghi P, Schuh R, Weisskopf L, Vavken P, Valderrabano V. Long-term biomechanical outcomes after Achilles tendon ruptures. Knee Surg Sports Traumatol Arthrosc. 2013 Oct 27. [Epub ahead of print] PMID: 24162761

Rosso C, Vavken P, Polzer C, Buckland DM, Studler U, Weisskopf L, Lottenbach M, Müller AM, Valderrabano V. Long-term outcomes of muscle volume and Achilles tendon length after Achilles tendon ruptures. Knee Surg Sports Traumatol Arthrosc. 2013 Jun;21(6):1369-77. doi: 10.1007/s00167-013-2407-1. Epub 2013 Jan 31. PMID: 23370984

Buckland DM, Jones DB. Should SAGES advance minimally invasive surgery in space? Surg Endosc. 2012 Feb;26(2):293-5. doi: 10.1007/s00464-011-1995-4. No abstract available. PMID: 22038168

Buhl LK, Jorquera RA, Akbergenova Y, Huntwork-Rodriguez S, Volfson D, Littleton JT Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin. Mol Cell Neurosci. 2013 Jan;52:161-72. doi: 10.1016/j.mcn.2012.11.009. Epub 2012 Nov 16. PMID: 23159779. PMCID: PMC3540146. NIHMS: NIHMS422753

Pietrusinski M, Severini G, Cajigas I, Mavroidis C, Bonato P. Design of a gait training device for control of pelvic obliquity. Conf Proc IEEE Eng Med Biol Soc. 2012;2012:3620-3. doi: 10.1109/EMBC.2012.6346750.PMID: 23366711

Cajigas I, Malik WQ, Brown EN. nSTAT: open-source neural spike train analysis toolbox for Matlab. J Neurosci Methods. 2012 Nov 15;211(2):245-64. doi: 10.1016/j.jneumeth.2012.08.009. Epub 2012 Sep 5. PMID: 22981419

Koenig A, Luft A, Cajigas I. Guest editorial: From neuroscience to neuro-rehabilitation: transferring basic neuroscientific principles from laboratory to bedside. J Neuroeng Rehabil. 2013 Jan 21;10:6. doi: 10.1186/1743-0003-10-6.PMID: 23336967

Von Keudell A, Syed HM, Canseco JA, Gomoll AH. Efficacy of common surgical compounds in preventing articular chondrocyte death from desiccation. Knee Surg Sports Traumatol Arthrosc. 2013 Sep 6. [Epub ahead of print] PMID: 24061713

Philip J, Hackl F, Canseco JA, Kamel RA, Kiwanuka E, Diaz-Siso JR, Caterson EJ, Junker JP, Eriksson E. Amnion-derived multipotent progenitor cells improve achilles tendon repair in rats. Eplasty. 2013 Jun 19;13:e31. Print 2013. PMID: 23814634

von Keudell A, Canseco JA, Gomoll AH. Deleterious Effects of Diluted Povidone-Iodine on Articular Cartilage. J Arthroplasty. 2013 Mar 22. doi:pii: S0883-5403(13)00189-7. 10.1016/j.arth.2013.02.018.PMID: 23528554

Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science. 2013 Oct 11;342(6155):253-7. doi: 10.1126/science.1242088. PMID: 24115442

Canver MC, Canver AC, Revere KE, Amado D, Bennett J, Chung DC. Novel mathematical algorithm for pupillometric data analysis. Comput Methods Programs Biomed. 2013 Sep 13. doi:pii: S0169-2607(13)00287-3. 10.1016/j.cmpb.2013.08.008. [Epub ahead of print] PMID: 24129048

Canver MC. Risk versus reward. IEEE Pulse. 2013 Mar-Apr;4(2):8-9. No abstract available. PMID: 23814921

Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. PMID: 23723238

Buchwalter G, Hickey MM, Cromer A, Selfors LM, Gunawardane RN, Frishman J, Jeselsohn R, Lim E, Chi D, Fu X, Schiff R, Brown M, Brugge JS. PDEF Promotes Luminal Differentiation and Acts as a Survival Factor for ER-Positive Breast Cancer Cells.Cancer Cell. 2013 Jun 10;23(6):753-67. doi: 10.1016/j.ccr.2013.04.026. PMID:23764000

Bowen SL, Byars LG, Michel CJ, Chonde DB, Catana C. Influence of the partial volume correction method on (18)F-fluorodeoxyglucose brain kinetic modelling from dynamic PET images reconstructed with resolution model based OSEM. Phys Med Biol. 2013 Oct 21;58(20):7081-106. doi: 10.1088/0031-9155/58/20/7081. Epub 2013 Sep 20. PubMed PMID: 24052021; PubMed Central PMCID: PMC4234075.

Schroeder FA, Chonde DB, Riley MM, Moseley CK, Granda ML, Wilson CM, Wagner FF, Zhang YL, Gale J, Holson EB, Haggarty SJ, Hooker JM. FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors. Neurosci Lett. 2013 Aug 29;550:119-24. doi: 10.1016/j.neulet.2013.06.016. Epub 2013 Jun 25. PubMed PMID: 23810801; PubMedCentral PMCID: PMC3750730.

Chonde DB, Abolmaali N, Arabasz G, Guimaraes AR, Catana C. Effect of MRI acoustic noise on cerebral fludeoxyglucose uptake in simultaneous MR-PET imaging. Invest Radiol. 2013 May;48(5):302-12. doi: 10.1097/RLI.0b013e3182839fbc. PubMed PMID: 23462677; PubMed Central PMCID: PMC3775482

Ciesienski KL, Yang Y, Ay I, Chonde DB, Loving GS, Rietz TA, Catana C, Caravan P. Fibrin-targeted PET probes for the detection of thrombi. Mol Pharm. 2013 Mar 4;10(3):1100-10. doi: 10.1021/mp300610s. Epub 2013 Jan 30. PubMed PMID: 23327109; PubMed Central PMCID: PMC3593967.

Hull CA, Chu Y, Thanawala M, Regehr WG. Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. J Neurosci. 2013 Apr 3;33(14):5895-902. doi: 10.1523/JNEUROSCI.4052-12.2013. PMID:23554471

Ebert DH, Gabel HW, Robinson ND, Kastan NR, Hu LS, Cohen S, Navarro AJ, Lyst MJ, Ekiert R, Bird AP, Greenberg ME. Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR. Nature. 2013 Jul 18;499(7458):341-5. doi: 10.1038/nature12348. PMID: 23770587

Awosogba T, Betancourt JR, Conyers FG, Estapé ES, Francois F, Gard SJ, Kaufman A, Lunn MR, Nivet MA, Oppenheim JD, Pomeroy C, Yeung H. Prioritizing health disparities in medical education to improve care. Ann N Y Acad Sci. 2013 May;1287(1):17-30. doi: 10.1111/nyas.12117. Epub 2013 May 9. PMID:2365967

Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat Biotechnol. 2013 Jan 29. doi: 10.1038/nbt.2508. PMID: 23360965

Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Multiplex Genome Engineering Using CRISPR/Cas Systems. Science. 2013 Jan 3. PMID: 23287718

Kim PG, Albacker CE, Lu YF, Jang IH, Lim Y, Heffner GC, Arora N, Bowman TV, Lin MI, Lensch MW, De Los Angeles A, Zon LI, Loewer S, Daley GQ. Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):E141-50. doi: 10.1073/pnas.1214361110. Epub 2012 Dec 12. PMID: 23236128

De Los Angeles A, Daley GQ. Stem cells: Reprogramming in situ. Nature. 2013 Oct 17;502(7471):309-10. doi: 10.1038/nature12559. Epub 2013 Sep 11. No abstract available.  PMID: 24025771

De Los Angeles A, Daley GQ. A chemical logic for reprogramming to pluripotency. Cell Res. 2013 Aug 27. doi: 10.1038/cr.2013.119. [Epub ahead of print] PMID: 23979017

Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. Nucleic Acids Res. 2013 Oct 1;41(19):9049-61. doi: 10.1093/nar/gkt555. Epub 2013 Jul 31. PMID: 23907390

Dickson JR, Kruse C, Montagna DR, Finsen B, Wolfe MS Alternative polyadenylation and miR-34 family members regulate tau expression. J Neurochem. 2013 Aug 28. doi: 10.1111/jnc.12437. [Epub ahead of print] PMID: 24032460

Franses JW, Drosu NC, Gibson WJ, Chitalia VC, Edelman ER. Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. Int J Cancer. 2013 Mar 5. doi: 10.1002/ijc.28146. PMID: 23463345

Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR. Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol. 2013 Oct;31(10):898-907. doi: 10.1038/nbt.2682. Epub 2013 Sep 8. PMID: 24013197

Petrossian MT, Paul LR, Multhaupt-Buell TJ, Eckhardt C, Hayes MT, Duhaime AC, Eskandar EN, Sharma N. Pallidal deep brain stimulation for dystonia: a case series. J Neurosurg Pediatr. 2013 Oct 4. [Epub ahead of print] PMID: 24093589

Sheth SA, Eckhardt CA, Walcott BP, Eskandar EN, Simon MV. Factors Affecting Successful Localization of the Central Sulcus Using the Somatosensory Evoked Potential Phase Reversal Technique. Neurosurgery. 2013 Feb 1. PMID:23381491

Eshel N, Tian J, Uchida N. Opening the black box: dopamine, predictions, and learning. Trends Cogn Sci. 2013 Sep;17(9):430-1. doi: 10.1016/j.tics.2013.06.010. Epub 2013 Jul 3. PMID: 23830895

Uchida N, Eshel N, Watabe-Uchida M. Division of labor for division: inhibitory interneurons with different spatial landscapes in the olfactory system. Neuron. 2013 Dec 4;80(5):1106-9. doi: 10.1016/j.neuron.2013.11.013. PMID: 24314722

Poduri A, Evrony GD, Cai X, Walsh CA Somatic mutation, genomic variation, and neurological disease. Science. 2013 Jul 5;341(6141):1237758. doi: 10.1126/science.1237758. Review.PMID: 23828942

Fink EC, Fisher DE. BRAF and MC1R in melanoma: different in head and neck tumors? J Invest Dermatol. 2013 Apr;133(4):878-80. doi: 10.1038/jid.2012.475.
PMID:23486431

Kolachalama VB, Pacetti SD, Franses JW, Stankus JJ, Zhao HQ, Shazly T, Nikanorov A, Schwartz LB, Tzafriri AR, Edelman ER. Mechanisms of Tissue Uptake and Retention in Zotarolimus-Coated Balloon Therapy. Circulation. 2013 Apr 12. PMID: 23584359

Franses JW, Drosu NC, Gibson WJ, Chitalia VC, Edelman ER. Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. Int J Cancer. 2013 Mar 5. doi: 10.1002/ijc.28146. PMID: 23463345

Demuth PC, Garcia-Beltran WF, Ai-Ling ML, Hammond PT, Irvine DJ. Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination. Adv Funct Mater. 2013 Jan 14;23(2):161-172. PMID: 23503923

Jost S, Moreno-Nieves UY, Garcia-Beltran WF, Rands K, Reardon J, Toth I, Piechocka-Trocha A, Altfeld M, Addo MM. Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection. Retrovirology. 2013 Jul 18;10:74. doi: 10.1186/1742-4690-10-74. PMID: 23866914

Baxt LA, Garza-Mayers AC, Goldberg MB. Bacterial subversion of host innate immune pathways. Science. 2013 May 10;340(6133):697-701. doi: 10.1126/science.1235771. Review. PMID: 23661751

Franses JW, Drosu NC, Gibson WJ, Chitalia VC, Edelman ER. Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. Int J Cancer. 2013 Mar 5. doi: 10.1002/ijc.28146. [Epub ahead of print] PMID: 23463345

Sah R, Mesirca P, Mason X, Gibson W, Bates-Withers C, Van den Boogert M, Chaudhuri D, Pu WT, Mangoni ME, Clapham DE. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation. 2013 Jul 9;128(2):101-14. doi: 10.1161/CIRCULATIONAHA.112.000768. Epub 2013 Jun 3. PMID: 23734001

David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, Ling AV, Devlin AS, Varma Y, Fischbach MA, Biddinger SB, Dutton RJ, Turnbaugh PJ. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014 Jan 23;505(7484):559-63. doi: 10.1038/nature12820. Epub 2013 Dec 11. PMID: 24336217

Haiser HJ, Gootenberg DB, Chatman K, Sirasani G, Balskus EP, Turnbaugh PJ. Predicting and manipulating cardiac drug inactivation by the human gut bacterium Eggerthella lenta. Science. 2013 Jul 19;341(6143):295-8. doi: 10.1126/science.1235872. PMID: 23869020

Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. J Clin Invest. 2013 Sep 3;123(9):4010-22. doi: 10.1172/JCI69443. Epub 2013 Aug 15. PMID: 23945236

Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC. The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. J Exp Med. 2013 Aug 26;210(9):1793-806. doi: 10.1084/jem.20111790. Epub 2013 Aug 5. PMID: 23918955

Greenblatt MB, Shim JH, Glimcher LH. Mitogen-Activated Protein Kinase Pathways in Osteoblasts. Annu Rev Cell Dev Biol. 2013 May 31. [Epub ahead of print] PMID: 23725048

Greenblatt MB, Aliprantis AO. The immune pathogenesis of scleroderma: context is everything. Curr Rheumatol Rep. 2013 Jan;15(1):297. doi: 10.1007/s11926-012-0297-8. Review. PMID: 23288576

Greenblatt MB, Ritter SY, Wright J, Tsang K, Hu D, Glimcher LH, Aliprantis AO. NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19914-9. doi: 10.1073/pnas.1320036110. Epub 2013 Nov 18. PMID:24248346. PMCID: PMC3856808

Greig LC, Woodworth MB, Galazo MJ, Padmanabhan H, Macklis JD. Molecular logic of neocortical projection neuron specification, development and diversity.
Nat Rev Neurosci. 2013 Nov;14(11):755-69. doi: 10.1038/nrn3586. Epub 2013 Oct 9. PMID: 24105342

Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki S, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, Rinn JL; 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC. Identifying recent adaptations in large-scale genomic data. Cell. 2013 Feb 14;152(4):703-13. doi: 10.1016/j.cell.2013.01.035. PMID: 23415221

Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki S, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, Rinn JL; 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC. Identifying recent adaptations in large-scale genomic data. Cell. 2013 Feb 14;152(4):703-13. doi: 10.1016/j.cell.2013.01.035. PMID: 23415221

Gui DY, Lewis CA, Vander Heiden MG. Allosteric regulation of PKM2 allows cellular adaptation to different physiological states. Sci Signal. 2013 Feb 19;6(263):pe7. doi: 10.1126/scisignal.2003925. PMID: 23423437

Hartl TA, Ni J, Cao J, Suyama KL, Patchett S, Bussiere C, Gui DY, Tang S, Kaplan DD, Fish M, Johnson AW, Scott MP. Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila. Genetics. 2013 May;194(1):101-15. doi: 10.1534/genetics.112.149104. Epub 2013 Feb 22. PMID: 23436180. PMCID: PMC3632458

Hanson KK, Ressurreição AS, Buchholz K, Prudêncio M, Herman-Ornelas JD, Rebelo M, Beatty WL, Wirth DF, Hänscheid T, Moreira R, Marti M, Mota MM. Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2838-47. doi: 10.1073/pnas.1306097110. Epub 2013 Jul 8. PMID: 23836641

Machado AC, Saleebyan SB, Holmes BT, Karelina M, Tam J, Kim SY, Kim KH, Dror I, Hodis E, Martz E, Compeau PA, Rohs R. Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes. Biochem Mol Biol Educ. 2012 Nov-Dec;40(6):400-1. doi: 10.1002/bmb.20650. Epub 2012 Oct 13. PMID: 23166030

Huang FW*, Hodis E*, Xu MJ, Kryukov GV, Chin L, Garraway LA. Highly Recurrent TERT Promoter Mutations in Human Melanoma. Science. 2013 Jan 24. PMID:23348506 (*Co-first authors)

Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, Ramos AH, Pugh TJ, Stransky N, Helman E, Kim J, Sougnez C, Ambrogio L, Nickerson E, Shefler E, Cortés ML, Auclair D, Saksena G, Voet D, Noble M, DiCara D, Lin P, Lichtenstein L, Heiman DI, Fennell T, Imielinski M, Hernandez B, Hodis E, Baca S, Dulak AM, Lohr J, Landau DA, Wu CJ, Melendez-Zajgla J, Hidalgo-Miranda A, Koren A, McCarroll SA, Mora J, Lee RS, Crompton B, Onofrio R, Parkin M, Winckler W, Ardlie K, Gabriel SB, Roberts CW, Biegel JA, Stegmaier K, Bass AJ, Garraway LA, Meyerson M, Golub TR, Gordenin DA, Sunyaev S, Lander ES, Getz G. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013 Jul 11;499(7457):214-8. doi: 10.1038/nature12213. Epub 2013 Jun 16. PMID: 23770567

Huang FW, Hodis E, Xu MJ, Kryukov GV, Chin L, Garraway LA. Highly recurrent TERT promoter mutations in human melanoma. Science. 2013 Feb 22;339(6122):957-9. doi: 10.1126/science.1229259. Epub 2013 Jan 24. PMID: 23348506

Nelson CD, Kim MJ, Hsin H, Chen Y, Sheng M. Phosphorylation of Threonine-19 of PSD-95 by GSK-3β is Required for PSD-95 Mobilization and Long-Term Depression. J Neurosci. 2013 Jul 17;33(29):12122-35. doi: 10.1523/JNEUROSCI.0131-13.2013.PMID: 23864697

Hu X, Kim H, Brennan PJ, Han B, Baecher-Allan CM, De Jager PL, Brenner MB, Raychaudhuri S. Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells. Proc Natl Acad Sci U S A. 2013 Nov 4. [Epub ahead of print] PMID: 24191009

Faris JE, Blaszkowsky LS, McDermott S, Guimaraes AR, Szymonifka J, Huynh MA, Ferrone CR, Wargo JA, Allen JN, Dias LE, Kwak EL, Lillemoe KD, Thayer SP, Murphy JE, Zhu AX, Sahani DV, Wo JY, Clark JW, Fernandez-del Castillo C, Ryan DP, Hong TS. FOLFIRINOX in locally advanced pancreatic cancer: the Massachusetts General Hospital Cancer Center experience. Oncologist. 2013;18(5):543-8. doi: 10.1634/theoncologist.2012-0435. Epub 2013 May 8. PMID: 23657686

Deindl S, Hwang WL, Hota SK, Blosser TR, Prasad P, Bartholomew B, Zhuang X. ISWI Remodelers Slide Nucleosomes with Coordinated Multi-Base-Pair Entry Steps and Single-Base-Pair Exit Steps. Cell. 2013 Jan 31;152(3):442-52. doi: 10.1016/j.cell.2012.12.040. PMID: 23374341

Pollock NR, McGray S, Colby DJ, Noubary F, Nguyen H, Nguyen TA, Khormaee S, Jain S, Hawkins K, Kumar S, Rolland JP, Beattie PD, Chau NV, Quang VM, Barfield C, Tietje K, Steele M, Weigl BH. Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test. PLoS One. 2013 Sep 30;8(9):e75616. doi: 10.1371/journal.pone.0075616. eCollection 2013. PubMed PMID: 24098705; PubMed Central PMCID: PMC3787037

Khormaee S, Choi Y, Shen MJ, Xu B, Wu H, Griffiths GL, Chen R, Slater NK, Park JK. Endosomolytic anionic polymer for the cytoplasmic delivery of siRNAs in localized in vivo applications. Adv Funct Mater. 2013 Feb 5;23(5). doi: 10.1002/adfm.201201945. PubMed PMID: 24273480; PubMed Central PMCID: PMC3834980.

Walcott BP, Kwon CS, Sheth SA, Fehnel CR, Koffie RM, Asaad WF, Nahed BV, Coumans JV. Predictors of cranioplasty complications in stroke and trauma patients. J Neurosurg. 2013 Feb 8. PMID:23394335

Knouse KA, Amon A. The many sides of CIN. Nat Rev Mol Cell Biol. 2013 Oct;14(10):611. doi: 10.1038/nrm3666. No abstract available.  PMID: 24061225

Oksenych V, Kumar V, Liu X, Guo C, Schwer B, Zha S, Alt FW. Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2234-9. doi: 10.1073/pnas.1222573110. Epub 2013 Jan 23. PMID: 23345432

Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ. Angiotensin II Drives the Production of Tumor-Promoting Macrophages. Immunity. 2013 Jan 15. doi:pii: S1074-7613(13)00003-4. 10.1016/j.immuni.2012.10.015. PMID:23333075

Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 5;155(6):1282-95. doi: 10.1016/j.cell.2013.10.054. PubMed PMID: 24315098; PubMed Central PMCID:PMC3894749.

Kwok SJ, El Kaffas A, Lai P, Al Mahrouki A, Lee J, Iradji S, Tran WT, Giles A, Czarnota GJ. Ultrasound-Mediated Microbubble Enhancement of Radiation Therapy Studied Using Three-Dimensional High-Frequency Power Doppler Ultrasound. Ultrasound Med Biol. 2013 Aug 28. doi:pii: S0301-5629(13)00642-X. 10.1016/j.ultrasmedbio.2013.03.025. [Epub ahead of print] PMID: 23993051

Hnisz D, Abraham BJ, Lee TI, Lau A, Saint-André V, Sigova AA, Hoke HA, Young RA. Super-Enhancers in the Control of Cell Identity and Disease. Cell. 2013 Oct 8. doi:pii: S0092-8674(13)01227-0. 10.1016/j.cell.2013.09.053. [Epub ahead of print] PMID: 24119843

Lovén J, Hoke HA, Lin CY, Lau A, Orlando DA, Vakoc CR, Bradner JE, Lee TI, Young RA. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell. 2013 Apr 11;153(2):320-34. doi: 10.1016/j.cell.2013.03.036.
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Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol. 2013 Feb;14(2):179-85. doi: 10.1038/ni.2509. Epub 2012 Dec 23. PMID: 23263557

Izar B, Sequist L, Lee M, Muzikansky A, Heist R, Iafrate J, Dias-Santagata D, Mathisen D, Lanuti M. The impact of EGFR mutation status on outcomes in patients with resected stage I non-small cell lung cancers. Ann Thorac Surg. 2013 Sep;96(3):962-8. doi: 10.1016/j.athoracsur.2013.05.091. Epub 2013 Aug 8. PMID: 23932319

Palazuelos D, Ellis K, Im DD, Peckarsky M, Schwarz D, Farmer DB, Dhillon R, Johnson A, Orihuela C, Hackett J, Bazile J, Berman L, Ballard M, Panjabi R, Ternier R, Slavin S, Lee S, Selinsky S, Mitnick CD. 5-SPICE: the application of an original framework for community health worker program design, quality improvement and research agenda setting. Glob Health Action. 2013 Apr 3;6:1-12. doi: 10.3402/gha.v6i0.19658. PMID: 23561023

Lemieux JE, Kyes SA, Otto TD, Feller AI, Eastman RT, Pinches RA, Berriman M, Su XZ, Newbold CI. Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation. Mol Microbiol. 2013 Aug 28. doi: 10.1111/mmi.12381. [Epub ahead of print] PMID: 23980881

Hsu AP, Johnson KD, Falcone EL, Sanalkumar R, Sanchez L, Hickstein DD, Cuellar-Rodriguez J, Lemieux JE, Zerbe CS, Bresnick EH, Holland SM.  GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome. Blood. 2013 May 9;121(19):3830-7, S1-7. doi: 10.1182/blood-2012-08-452763. Epub 2013 Mar 15. PMID: 23502222

Leskov I, Pallasch CP, Drake A, Iliopoulou BP, Souza A, Shen CH, Schweighofer CD, Abruzzo L, Frenzel LP, Wendtner CM, Hemann MT, Chen J. Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies. Oncogene. 2013 Feb 21;32(8):1066-72. doi: 10.1038/onc.2012.117. Epub 2012 Apr 9. PMID: 22484426

Gupta M, Leskov I, Kruger JM, Cestari DM.  Intermittent Horner Syndrome in a Pediatric Patient. J Neuroophthalmol. 2013 Oct 16. [Epub ahead of print] PMID: 24135969

Plovanich M, Bogorad RL, Sancak Y, Kamer KJ, Strittmatter L, Li AA, Girgis HS, Kuchimanchi S, De Groot J, Speciner L, Taneja N, Oshea J, Koteliansky V, Mootha VK. MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling. PLoS One. 2013;8(2):e55785. doi: 10.1371/journal.pone.0055785. Epub 2013 Feb 7. PMID: 23409044

Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 2013 Sep 12;154(6):1380-9. doi: 10.1016/j.cell.2013.08.021. Epub 2013 Aug 29. PMID: 23992846

David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, Ling AV, Devlin AS, Varma Y, Fischbach MA, Biddinger SB, Dutton RJ, Turnbaugh PJ. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014 Jan 23;505(7484):559-63. doi: 10.1038/nature12820. Epub 2013 Dec 11. PubMed PMID:24336217; PubMed Central PMCID: PMC3957428.

Liu WW, Wilson RI. Transient and specific inactivation of Drosophila neurons in vivo using a native ligand-gated ion channel. Curr Biol. 2013 Jul 8;23(13):1202-8. doi: 10.1016/j.cub.2013.05.016. Epub 2013 Jun 13. PMID: 23770187

Liu WW, Wilson RI. Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10294-9. doi: 10.1073/pnas.1220560110. Epub 2013 May 31. PMID: 23729809

Morgan AM, Lo J, Fisher DE. How does pheomelanin synthesis contribute to melanomagenesis?: Two distinct mechanisms could explain the carcinogenicity of pheomelanin synthesis. Bioessays. 2013 Aug;35(8):672-6. doi: 10.1002/bies.201300020. Epub 2013 May 7.PMID: 23650156

Lo JH, von Maltzahn G, Douglass J, Park JH, Sailor MJ, Ruoslahti E, Bhatia SN. Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sites. J Mater Chem B Mater Biol Med. 2013 Oct 21;1(39):5235-5240. Epub 2013 Jun 14. PMID: 24177171

Yu TW, Chahrour MH, Coulter ME, Jiralerspong S, Okamura-Ikeda K, Ataman B, Schmitz-Abe K, Harmin DA, Adli M, Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J, Nasir RH, Ware J, Joseph RM, Hill RS, Kwan BY, Al-Saffar M, Mukaddes NM, Hashmi A, Balkhy S, Gascon GG, Hisama FM, Leclair E, Poduri A, Oner O, Al-Saad S, Al-Awadi SA, Bastaki L, Ben-Omran T, Teebi AS, Al-Gazali L, Eapen V, Stevens CR, Rappaport L, Gabriel SB, Markianos K, State MW, Greenberg ME, Taniguchi H, Braverman NE, Morrow EM, Walsh CA. Using Whole-Exome Sequencing to Identify Inherited Causes of Autism. Neuron. 2013 Jan 23;77(2):259-273. doi: 10.1016/j.neuron.2012.11.002. Epub 2013 Jan 23. PMID: 23352163

Fendt SM, Bell EL, Keibler MA, Olenchock BA, Mayers JR, Wasylenko TM, Vokes NI, Guarente L, Vander Heiden MG, Stephanopoulos G. Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells. Nat Commun. 2013 Jul 31;4:2236. doi: 10.1038/ncomms3236. PMID: 23900562

Mayers JR, Vander Heiden MG. BCAT1 defines gliomas by IDH status. Nat Med. 2013 Jul;19(7):816-7. doi: 10.1038/nm.3263. No abstract available.  PMID: 23836221

Fendt SM, Bell EL, Keibler MA, Davidson SM, Wirth GJ, Fiske B, Mayers JR, Schwab M, Bellinger G, Csibi A, Patnaik A, Blouin MJ, Cantley LC, Guarente L, Blenis J, Pollak MN, Olumi AF, Vander Heiden MG, Stephanopoulos G.  Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism. Cancer Res. 2013 Jul 15;73(14):4429-38. doi: 10.1158/0008-5472.CAN-13-0080. Epub 2013 May 17. PMID: 23687346

Mayne EW, Craig MT, McBain CJ, Paulsen O. Dopamine suppresses persistent network activity via D(1) -like dopamine receptors in rat medial entorhinal cortex. Eur J Neurosci. 2013 Jan 22. doi: 10.1111/ejn.12125. PMID: 23336973

Craig MT, Mayne EW, Bettler B, Paulsen O, McBain CJ. Distinct roles of GABAB1a- and GABAB1b-containing GABA(B) receptors in spontaneous and evoked termination of persistent cortical activity. J Physiol. 2013 Jan 21. PMID: 23266934

Davoli T, Xu AW, Mengwasser KE, Sack LM, Yoon JC, Park PJ, Elledge SJ. Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome. Cell. 2013 Oct 30. doi:pii: S0092-8674(13)01287-7. 10.1016/j.cell.2013.10.011. [Epub ahead of print] PMID: 24183448

Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, Ramos AH, Pugh TJ, Stransky N, Helman E, Kim J, Sougnez C, Ambrogio L, Nickerson E, Shefler E, Cortés ML, Auclair D, Saksena G, Voet D, Noble M, DiCara D, Lin P, Lichtenstein L, Heiman DI, Fennell T, Imielinski M, Hernandez B, Hodis E, Baca S, Dulak AM, Lohr J, Landau DA, Wu CJ, Melendez-Zajgla J, Hidalgo-Miranda A, Koren A, McCarroll SA, Mora J, Lee RS, Crompton B, Onofrio R, Parkin M, Winckler W, Ardlie K, Gabriel SB, Roberts CW, Biegel JA, Stegmaier K, Bass AJ, Garraway LA, Meyerson M, Golub TR, Gordenin DA, Sunyaev S, Lander ES, Getz G. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013 Jul 11;499(7457):214-8. doi: 10.1038/nature12213. Epub 2013 Jun 16.PMID: 23770567

Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC. Systematic Interrogation of 3q26 Identifies TLOC1 and SKIL as Cancer Drivers. Cancer Discov. 2013 Aug 22. [Epub ahead of print] PMID: 23764425

Verhaak RG, Tamayo P, Yang JY, Hubbard D, Zhang H, Creighton CJ, Fereday S, Lawrence M, Carter SL, Mermel CH, Kostic AD, Etemadmoghadam D, Saksena G, Cibulskis K, Duraisamy S, Levanon K, Sougnez C, Tsherniak A, Gomez S, Onofrio R, Gabriel S, Chin L, Zhang N, Spellman PT, Zhang Y, Akbani R, Hoadley KA, Kahn A, Köbel M, Huntsman D, Soslow RA, Defazio A, Birrer MJ, Gray JW, Weinstein JN, Bowtell DD, Drapkin R, Mesirov JP, Getz G, Levine DA, Meyerson M; Cancer Genome Atlas Research Network. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. J Clin Invest. 2013 Jan 2;123(1):517-25. doi: 10.1172/JCI65833. Epub 2012 Dec 21.PMID: 23257362

Baron JM, Mermel CH, Lewandrowski KB, Dighe AS. Detection of preanalytic laboratory testing errors using a statistically guided protocol. Am J Clin Pathol. 2012 Sep;138(3):406-13. doi: 10.1309/AJCPQIRIB3CT1EJV.
PMID: 22912358

Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling. Cancer Cell. 2013 Jul 8;24(1):45-58. doi: 10.1016/j.ccr.2013.05.004. Epub 2013 Jun 13. PMID: 23770013

Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MA, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013 Dec;9(12):840-8. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27.PMID: 24161946

Frederick DT, Piris A, Cogdill AP, Cooper ZA, Lezcano C, Ferrone CR, Mitra D, Boni A, Newton LP, Liu C, Peng W, Sullivan RJ, Lawrence DP, Hodi FS, Overwijk WW, Lizée G, Murphy GF, Hwu P, Flaherty KT, Fisher DE, Wargo JA. BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma. Clin Cancer Res. 2013 Jan 30.PMID:23307859

Liu S, Wang J, Su Y, Guerrero C, Zeng Y, Mitra D, Brooks PJ, Fisher DE, Song H, Wang Y. Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA. Nucleic Acids Res. 2013 Jul;41(13):6421-9. doi: 10.1093/nar/gkt360. Epub 2013 May 8. PMID:23658232

Morgan AM, Lo J, Fisher DE. How does pheomelanin synthesis contribute to melanomagenesis?: Two distinct mechanisms could explain the carcinogenicity of pheomelanin synthesis. Bioessays. 2013 Aug;35(8):672-6. doi: 10.1002/bies.201300020. Epub 2013 May 7.PMID: 23650156

Chellappa V, Taylor KN, Pedrick K, Donado C, Netravali IA, Haider K, Cariappa A, Dalomba NF, Pillai S. M89V Sialic acid Acetyl Esterase (SIAE) and all other non-synonymous common variants of this gene are catalytically normal. PLoS One. 2013;8(1):e53453. doi: 10.1371/journal.pone.0053453. Epub 2013 Jan 7. PMID:23308225

Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK. In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites. Nucleic Acids Res. 2013 Aug 14. [Epub ahead of print) PMID: 23945932

Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat Biotechnol. 2013 Aug 11. doi: 10

Peters DT, Cowan CA, Musunuru K. Genome editing in human pluripotent stem cells. StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.2013 Apr 29. PMID: 23785737

Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 2013 Feb 7;12(2):238-51. doi: 10.1016/j.stem.2012.11.011. Epub 2012 Dec 13. PMID: 23246482

Porter Saltzman, Amy, Tracking Immobilities: Explorations of In-Access to Healthcare Resources Among South African Labor Migrants (April 12, 2013). Available at SSRN: http://ssrn.com/abstract=2250202

Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 2013 Jul 8;24(1):45-58. doi: 10.1016/j.ccr.2013.05.004. Epub 2013 Jun 13. PMID: 23770013

Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MA, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013 Dec;9(12):840-8. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27.PMID: 24161946

Puram SV, Hasserjian RP, Faquin WC, Lin HW, Rocco JW. Castleman disease presenting in the neck: Report of a case and review of the literature. Am J Otolaryngol. 2013 Jan 31. doi:pii: S0196-0709(12)00256-6. 10.1016/j.amjoto.2012.11.007. PMID:23375540

Puram SV, Kim AH, Park HY, Anckar J, Bonni A. The Ubiquitin Receptor S5a/Rpn10 Links Centrosomal Proteasomes with Dendrite Development in the Mammalian Brain. Cell Rep. 2013 Jul 2. doi:pii: S2211-1247(13)00284-2. 10.1016/j.celrep.2013.06.006. [Epub ahead of print] PMID: 23831032

Gurtan AM, Ravi A, Rahl PB, Bosson AD, JnBaptiste CK, Bhutkar A, Whittaker CA, Young RA, Sharp PA. Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts. Genes Dev. 2013 Apr 15;27(8):941-54. doi: 10.1101/gad.215376.113. PMID: 23630078

Ravi A, Rao VR, Klein JP. Dystextia: acute stroke in the modern age. JAMA Neurol. 2013 Mar 1;70(3):404-5. No abstract available.  PMID:23599944

Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. Nucleic Acids Res. 2013 Oct 1;41(19):9049-61. doi: 10.1093/nar/gkt555. Epub 2013 Jul 31. PMID: 23907390

Li G, Diogo D, Wu D, Spoonamore J, Dancik V, Franke L, Kurreeman F, Rossin EJ, Duclos G, Hartland C, Zhou X, Li K, Liu J, De Jager PL, Siminovitch KA, Zhernakova A, Raychaudhuri S, Bowes J, Eyre S, Padyukov L, Gregersen PK, Worthington J; Rheumatoid Arthritis Consortium International (RACI), Gupta N, Clemons PA, Stahl E, Tolliday N, Plenge RM. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.
PLoS Genet. 2013 May;9(5):e1003487. doi: 10.1371/journal.pgen.1003487. Epub 2013 May 16. PMID: 23696745

Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, Lehtimäki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Schürks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, Färkkilä M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PA, Montgomery GW, Martin NG, Borck G, Göbel H, Heinze A, Heinze-Kuhn K, Williams FM, Hartikainen AL, Pouta A, van den Ende J, Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, Heikkilä K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor BJ, Trabzuni D, Rossin E, et al.  North American Brain Expression Consortium; UK Brain Expression Consortium; International Headache Genetics Consortium. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Aug;45(8):912-7. doi: 10.1038/ng.2676. Epub 2013 Jun 23. PMID: 23793025

den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Müller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ,, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14. PMID: 23583979

Kirby A, Gnirke A, Jaffe DB, Barešová V, Pochet N, Blumenstiel B, Ye C, Aird D, Stevens C, Robinson JT, Cabili MN, Gat-Viks I, Kelliher E, Daza R, Defelice M, Hůlková H, Sovová J, Vylet'al P, Antignac C, Guttman M, Handsaker RE, Perrin D, Steelman S, Sigurdsson S, Scheinman SJ, Sougnez C, Cibulskis K, Parkin M, Green T, Rossin E, Zody MC, Xavier RJ, Pollak MR, Alper SL, Lindblad-Toh K, Gabriel S, Hart PS, Regev A, Nusbaum C, Kmoch S, Bleyer AJ, Lander ES, Daly MJ. Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing. Nat Genet. 2013 Mar;45(3):299-303. doi: 10.1038/ng.2543. Epub 2013 Feb 10. PMID:23396133

Schwartz, A., Magoulas, R. and Buntin, M. (2013), Tracking Labor Demand with Online Job Postings: The Case of Health IT Workers and the HITECH Act. Industrial Relations: A Journal of Economy and Society, 52: 941-968. doi: 10.1111/irel.12041

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March S, Ng S, Velmurugan S, Galstian A, Shan J, Logan DJ, Carpenter AE, Thomas D, Sim BK, Mota MM, Hoffman SL, Bhatia SN. A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax. Cell Host Microbe. 2013 Jul 17;14(1):104-15. doi: 10.1016/j.chom.2013.06.005. PMID: 23870318  PMCID: PMC3780791

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