Publications

2012

Helguera G, Jemielity S, Abraham J, Cordo SM, Martinez MG, Rodríguez JA, Bregni C, Wang JJ, Farzan M, Penichet ML, Candurra NA, Choe H. An antibody recognizing the apical domain of human transferrin receptor 1 efficiently inhibits the entry of all new world hemorrhagic Fever arenaviruses. J Virol. 2012 Apr;86(7):4024-8. Epub 2012 Jan 25. PMID:22278244.

Engreitz JM, Agarwala V, Mirny LA. Three-dimensional genome architecture influences partner selection for chromosomal translocations in human disease. PLoS One. 2012;7(9):e44196. doi: 10.1371/journal.pone.0044196. Epub 2012 Sep 28. PMID: 23028501

Kwong GA, von Maltzahn G, Murugappan G, Abudayyeh O, Mo S, Papayannopoulos IA, Sverdlov DY, Liu SB, Warren AD, Popov Y, Schuppan D, Bhatia SN. Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease. Nat Biotechnol. 2012 Dec 16. doi: 10.1038/nbt.2464. [Epub ahead of print] PMID: 23242163

Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C. SAP expression in invariant NKT cells is requisite for cognate help and dispensable for non-cognate support to B cells. Blood. 2012 May 21. [Epub ahead of print] PMID: 22613797.

Ejaz S, Williamson DJ, Ahmed T, Sitnikov S, Hong YT, Sawiak SJ, Fryer TD, Aigbirhio FI, Baron JC. Characterizing infarction and selective neuronal loss following temporary focal cerebral ischemia in the rat: A multi-modality imaging study.Neurobiol Dis. 2013 Mar;51:120-32. doi: 10.1016/j.nbd.2012.11.002. Epub 2012 Nov 10.PMID: 23146994

Yang W, Rudick CN, Hoxha E, Allsop SA, Dimitrakoff JD, Klumpp DJ. Ca(2+)/calmodulin-dependent protein kinase II is associated with pelvic pain of neurogenic cystitis. Am J Physiol Renal Physiol. 2012 Aug 1;303(3):F350-6. Epub 2012 May 30. PMID: 22647634

Varadarajan N, Kwon DS, Law KM, Ogunniyi AO, Anahtar MN, Richter JM, Walker BD, Love JC. Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3885-90. Epub 2012 Feb 21. PMID:22355106.

Alenghat FJ, Baca QJ, Rubin NT, Pao LI, Matozaki T, Lowell CA, Golan DE, Neel BG, Swanson KD.. Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement. J Cell Sci. 2012 Sep 12. [Epub ahead of print] PMID: 22976304

Baca SC, Garraway LA. The genomic landscape of prostate cancer. Front Endocrinol (Lausanne). 2012;3:69. Epub 2012 May 16. PMID: 22649426.

Dulak AM, Schumacher S, van Lieshout J, Imamura Y, Fox C, Shim B, Ramos A, Saksena G, Baca S, Baselga J, Tabernero J, Barretina J, Enzinger P, Corso G, Roviello F, Lin L, Bandla S, Luketich J, Pennathur A, Meyerson M, Ogino S, Shivdasani RA, Beer DG, Godfrey TE, Beroukhim R, Bass AJ. Gastrointestinal adenocarcinomas of the esophagus, stomach and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res. 2012 Jul 2. [Epub ahead of print] PMID:22751462.

Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, Park K, Kitabayashi N, Macdonald TY, Sheikh K, Vuong T, Guiducci C, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Hussain WM, Ramos AH, Winckler W, Redman MC, Ardlie K, Tewari AK, Mosquera JM, Rupp N, Wild PJ, Moch H, Morrissey C, Nelson PS, Kantoff PW, Gabriel SB, Golub TR, Meyerson M, Lander ES, Getz G, Rubin MA, Garraway LA. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet. 2012 May 20;44(6):685-9. doi: 10.1038/ng.2279. PMID:22610119.

Lin, KY, Bagley, AF, Zhang, AY, Karl, DL, Yoon, SS, Bhatia, SN (2012): Gold nanorod photothermal therapy in a genetically engineered mouse model of soft tissue sarcoma. Nano LIFE, published online February, 2012. DOI: 10.1142/S1793984410000262.

Bagley AF, Daneshvar DH, Schanker BD, Zurakowski D, Dʼhemecourt CA, Nowinski CJ, Cantu RC, Goulet K. Effectiveness of the SLICE Program for Youth Concussion Education. Clin J Sport Med. 2012 Sep;22(5):385-389. PMID: 22929042

Bick AG, Calvo SE, Mootha VK. Evolutionary diversity of the mitochondrial calcium uniporter. Science. 2012 May 18;336(6083):886. PMID: 22605770.

Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, Depalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA Jr, Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C. Burden of rare sarcomere gene variants in the framingham and jackson heart study cohorts. Am J Hum Genet. 2012 Sep 7;91(3):513-9. PMID: 22958901

Christen T, Bolar DS, Zaharchuk G. Imaging Brain Oxygenation with MRI Using Blood Oxygenation Approaches: Methods, Validation, and Clinical Applications. AJNR Am J Neuroradiol. 2012 Aug 2. [Epub ahead of print]. PMID:22859287

Cajigas I, Malik WQ, Brown EN. nSTAT: Open-source neural spike train analysis toolbox for Matlab. J Neurosci Methods. 2012 Sep 5;211(2):245-264. doi: 10.1016/j.jneumeth.2012.08.009]. PMID: 22981419

Canseco JA, Kojima K, Penvose AR, Ross JD, Obokata H, Gomoll AH, Vacanti CA. Effect on Ligament Marker Expression by Direct-Contact Co-Culture of Mesenchymal Stem Cells and Anterior Cruciate Ligament Cells. Tissue Eng Part A. 2012 Jul 10. PMID: 22780864.

Canver MC. Second preclinical year [perspectives on graduate life]. IEEE Pulse. 2012 Mar;3(2):7-8. No abstract available. PMID: 22577703.

Canver MC. Transitioning to a physician scientist. IEEE Pulse. 2012 May-Jun;3(3):10, 12. No abstract available. PMID: 22860265

Canver MC. Graduate school: the problem of choice. IEEE Pulse. 2012 Jul;3(4):8, 10. No abstract available. PMID: 23008839

Birsoy K, Wang T, Possemato R, Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y, Peterson TR, Carette JE, Brummelkamp TR, Clish CB, Sabatini DM.MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors. Nat Genet. 2012 Dec 16;45(1):104-8. doi: 10.1038/ng.2471. Epub 2012 Dec 2. PMID: 23202129

Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D. Direct observation of the interconversion of normal and toxic forms of α-synuclein. Cell. 2012 May 25;149(5):1048-59. PMID: 22632969

Chen YE, Gerstle TL, Liang F, Lee BT. Use of a novel laser projection grid to assess symmetry in breast surgery. Plast Reconstr Surg. 2012 Jul;130(1):231e-3e. PMID: 22743944.

Cheng A, Lu TK. Synthetic Biology: An Emerging Engineering Discipline. Annu Rev Biomed Eng. 2012 May 7. [Epub ahead of print]. PMID:22577777.

Shaw TJ, Pernar LI, Peyre SE, Helfrick JF, Vogelgesang KR, Graydon-Baker E, Chretien Y, Brown EJ, Nicholson JC, Heit JJ, Co JP, Gandhi T. Impact of online education on intern behaviour around joint commission national patient safety goals: a randomised trial. BMJ Qual Saf. 2012 Oct;21(10):819-25. Epub 2012 Jun 16. PMID: 22706930

Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature. 2012 Jul 1. doi: 10.1038/nature11310. [Epub ahead of print] PMID: 22763451.

Chu Y, Fioravante D, Thanawala M, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. J Neurosci. 2012 Oct 3;32(40):13796-804. doi: 10.1523/JNEUROSCI.2158-12.2012. PMID: 23035091

Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME. Bhlhb5 and prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303.PMID: 22284184.

Hutchinson AN, Deng JV, Cohen S, West AE. Phosphorylation of MeCP2 at Ser421 Contributes to Chronic Antidepressant Action. J Neurosci. 2012 Oct 10;32(41):14355-63. doi: 10.1523/JNEUROSCI.2156-12.2012. PMID: 23055506

Sengupta P, Basu S, Soni S, Pandey A, Roy B, Oh MS, Chin KT, Paraskar AS, Sarangi S, Connor Y, Sabbisetti VS, Kopparam J, Kulkarni A, Muto K, Amarasiriwardena C, Jayawardene I, Lupoli N, Dinulescu DM, Bonventre JV, Mashelkar RA, Sengupta S. Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity. Proc Natl Acad Sci U S A. 2012 Jun 25. [Epub ahead of print] PMID: 22733767.

Chahrour MH, Yu TW, Lim ET, Ataman B, Coulter ME, Hill RS, Stevens CR, Schubert CR; ARRA Autism Sequencing Collaboration, Greenberg ME, Gabriel SB, Walsh CA. Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism. PLoS Genet. 2012;8(4):e1002635. Epub 2012 Apr 12. PMID: 22511880.

Yu TW, Chahrour MH, Coulter ME, Jiralerspong S, Okamura-Ikeda K, Ataman B, Schmitz-Abe K, Harmin DA, Adli M, Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J, Nasir RH, Ware J, Joseph RM, Hill RS, Kwan BY, Al-Saffar M, Mukaddes NM, Hashmi A, Balkhy S, Gascon GG, Hisama FM, Leclair E, Poduri A, Oner O, Al-Saad S, Al-Awadi SA, Bastaki L, Ben-Omran T, Teebi AS, Al-Gazali L, Eapen V, Stevens CR, Rappaport L, Gabriel SB, Markianos K, State MW, Greenberg ME, Taniguchi H, Braverman NE, Morrow EM, Walsh CA. Using Whole-Exome Sequencing to Identify Inherited Causes of Autism. Neuron. 2013 Jan 23;77(2):259-273. doi: 10.1016/j.neuron.2012.11.002. PMID: 23352163

Woodworth MB, Custo Greig L, Kriegstein AR, Macklis JD. SnapShot: cortical development. Cell. 2012 Nov 9;151(4):918-918.e1. doi: 10.1016/j.cell.2012.10.004. No abstract available. PMID: 23141546

Yu TW, Chahrour MH, Coulter ME, Jiralerspong S, Okamura-Ikeda K, Ataman B, Schmitz-Abe K, Harmin DA, Adli M, Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J, Nasir RH, Ware J, Joseph RM, Hill RS, Kwan BY, Al-Saffar M, Mukaddes NM, Hashmi A, Balkhy S, Gascon GG, Hisama FM, Leclair E, Poduri A, Oner O, Al-Saad S, Al-Awadi SA, Bastaki L, Ben-Omran T, Teebi AS, Al-Gazali L, Eapen V, Stevens CR, Rappaport L, Gabriel SB, Markianos K, State MW, Greenberg ME, Taniguchi H, Braverman NE, Morrow EM, Walsh CA. Using Whole-Exome Sequencing to Identify Inherited Causes of Autism. Neuron. 2013 Jan 23;77(2):259-273. doi: 10.1016/j.neuron.2012.11.002. PMID: 23352163

De Los Angeles A, Loh YH, Tesar PJ, Daley GQ. Accessing naïve human pluripotency. Curr Opin Genet Dev. 2012 Jun;22(3):272-82. Epub 2012 Mar 29. PMID:22463982.

Loh YH, Yang JC, De Los Angeles A, Guo C, Cherry A, Rossi DJ, Park IH, Daley GQ. Excision of a viral reprogramming cassette by delivery of synthetic cre mRNA. Curr Protoc Stem Cell Biol. 2012 May;Chapter 4:Unit4A.5. PMID:22605648.

Pashai N, Hao H, All A, Gupta S, Chaerkady R, De Los Angeles A, Gearhart JD, Kerr CL Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells. PLoS One. 2012;7(6):e39088. Epub 2012 Jun 21. PMID: 22737227.

Chen Q, Cichon J, Wang W, Qiu L, Lee SJ, Campbell NR, Destefino N, Goard MJ, Fu Z, Yasuda R, Looger LL, Arenkiel BR, Gan WB, Feng G. Imaging neural activity using Thy1-GCaMP transgenic mice. Neuron. 2012 Oct 18;76(2):297-308. doi: 10.1016/j.neuron.2012.07.011. Epub 2012 Oct 17. PMID: 23083733

Lewis LD, Weiner VS, Mukamel EA, Donoghue JA, Eskandar EN, Madsen JR, Anderson WS, Hochberg LR, Cash SS, Brown EN, Purdon PL. Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):E3377-86. doi: 10.1073/pnas.1210907109. Epub 2012 Nov 5. PMID: 23129622

Bourne SK, Eckhardt CA, Sheth SA, Eskandar EN Mechanisms of deep brain stimulation for obsessive compulsive disorder: effects upon cells and circuits. Front Integr Neurosci. 2012;6:29. Epub 2012 Jun 14.PMID:22712007.

D'Ardenne K, Eshel N, Luka J, Lenartowicz A, Nystrom LE, Cohen JD. Role of prefrontal cortex and the midbrain dopamine system in working memory updating. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19900-9. doi: 10.1073/pnas.1116727109. Epub 2012 Oct 18. PMID: 23086162

Poduri A, Evrony GD, Cai X, Elhosary PC, Beroukhim R, Lehtinen MK, Hills LB, Heinzen EL, Hill A, Hill RS, Barry BJ, Bourgeois BF, Riviello JJ, Barkovich AJ, Black PM, Ligon KL, Walsh CA Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron. 2012 Apr 12;74(1):41-8. PMID: 22500628.

Evrony GD*, Cai X*, Lee E, Hills LB, Elhosary PC, Lehmann HS, Parker JJ, Atabay KD, Gilmore EC, Poduri A, Park PJ, Walsh, CA. Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain. Cell. 2012 Oct 26;151(3):483-96. PMID:23101622.

Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol. 2012 Oct;13(10):972-80. doi: 10.1038/ni.2420. Epub 2012 Sep 9. PMID: 22961053

Fassett MS, Jiang W, D'Alise AM, Mathis D, Benoist C Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3891-6. Epub 2012 Feb 15. PMID: 22345564

Clapham KR, Yu TW, Ganesh VS, Barry B, Chan Y, Mei D, Parrini E, Funalot B, Dupuis L, Nezarati MM, du Souich C, van Karnebeek C, Guerrini R, Walsh CA. FLNA genomic rearrangements cause periventricular nodular heterotopia.Neurology. 2012 Jan 24;78(4):269-78. Epub 2012 Jan 11. PMID: 22238415

Mochida GH, Ganesh VS, de Michelena MI, Dias H, Atabay KD, Kathrein KL, Huang HT, Hill RS, Felie JM, Rakiec D, Gleason D, Hill AD, Malik AN, Barry BJ, Partlow JN, Tan WH, Glader LJ, Barkovich AJ, Dobyns WB, Zon LI, Walsh CA. CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nat Genet. 2012 Sep 30. doi: 10.1038/ng.2425. [Epub ahead of print] PMID: 23023333

Cabán-Martinez AJ, (Garcia) Beltrán WF. Advancing medicine one research note at a time: the educational value in clinical case reports. BMC Res Notes. 2012 Jul 6;5:293. PMID: 22697904
Yang YJ, Baltus AE, Mathew RS, Murphy EA, Evrony GD, Gonzalez DM, Wang EP, Marshall-Walker CA, Barry BJ, Murn J, Tatarakis A, Mahajan MA, Samuels HH, Shi Y, Golden JA, Mahajnah M, Shenhav R, Walsh CA. Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation. Cell. 2012 Nov 21;151(5):1097-1112. doi: 10.1016/j cell.2012.10.043. PMID: 23178126

Barral DC, Garg S, Casalou C, Watts GF, Sandoval JL, Ramalho JS, Hsu VW, Brenner MB. Arl13b regulates endocytic recycling traffic. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21354-9. doi 10.1073/pnas.1218272110. Epub 2012 Dec 7. PMID: 23223633

Greenblatt MB, Sargent JL, Farina G, Tsang K, Lafyatis R, Glimcher LH, Whitfield ML, Aliprantis AO. Interspecies Comparison of Human and Murine Scleroderma Reveals IL-13 and CCL2 as Disease Subset-Specific Targets. Am J Pathol. 2012 Mar;180(3):1080-94. Epub 2012 Jan 11. PMID: 22245215.

Greenblatt MB, Vbranac V, Tivey T, Tsang K, Tager AM, Aliprantis AO Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model. PLoS One. 2012;7(9):e44664. Epub 2012 Sep 5. PMID:22957096

Andersen KG, Shylakhter I, Tabrizi S, Grossman SR, Happi CT, Sabeti PC. Genome-wide scans provide evidence for positive selection of genes implicated in Lassa fever. Philos Trans R Soc Lond B Biol Sci. 2012 Mar 19;367(1590):868-77. PMID:22312054.

Sung JH, Zhang H, Moseman EA, Alvarez D, Iannacone M, Henrickson SE, de la Torre JC, Groom JR, Luster AD, von Andrian UH. Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes. Cell. 2012 Sep 14;150(6):1249-63. doi: 10.1016/j.cell.2012.08.015. PMID: 22980984

Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, Depalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA Jr, Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C. Burden of rare sarcomere gene variants in the framingham and jackson heart study cohorts. Am J Hum Genet. 2012 Sep 7;91(3):513-9. PMID: 22958901

Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE. Truncations of titin causing dilated cardiomyopathy.
N Engl J Med. 2012 Feb 16;366(7):619-28. PMID: 22335739

Hu X, Daly M. What have we learned from six years of GWAS in autoimmune diseases, and what is next? Curr Opin Immunol. 2012 Oct;24(5):571-5. doi: 10.1016/j.coi.2012.09.001. Epub 2012 Sep 24. Review. PMID:23017373

Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium, Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11.PMID:23143596

Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H; International IBD Genetics Consortium (IIBDGC), Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582. PMID: 23128233

Tantama M, Hung YP, Yellen G. Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain. Prog Brain Res. 2012;196:235-63. PMID: 22341329.

Hwang J, Jaroensuk J, Leimanis ML, Russell B, McGready R, Day N, Snounou G, Nosten F, Imwong M. Long-term storage limits PCR-based analyses of malaria parasites in archival dried blood spots. Malar J. 2012 Oct 8;11:339. doi: 10.1186/1475-2875-11-339. PMID: 23043522

Khormaee S, Ali OA, Chodosh J, Mooney DJ. Optimizing siRNA efficacy through alteration in the target cell-adhesion substrate interaction. J Biomed Mater Res A. 2012 Oct;100(10):2637-43. doi: 10.1002/jbm.a.34202. Epub 2012 May 21. PMID:22615234.

Koffie RM, Lee S, Perez-Atayde A, Mooney DP. Periampullary duodenal duplication cyst masquerading as a choledochocele. Pediatr Surg Int. 2012 Jul 1. [Epub ahead of print] PMID:22752148.

Koffie RM, Hashimoto T, Tai HC, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM, Holtzman DM, Hyman BT, Spires-Jones TL. Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. Brain. 2012 Jul;135(Pt 7):2155-68. Epub 2012 May 26. PMID: 22637583.

Wood KC, Konieczkowski DJ, Johannessen CM, Boehm JS, Tamayo P, Botvinnik OB, Mesirov JP, Hahn WC, Root DE, Garraway LA, Sabatini DM. MicroSCALE Screening Reveals Genetic Modifiers of Therapeutic Response in Melanoma. Sci Signal. 2012 May 15;5(224):rs4. PMID: 22589389

Konieczkowski DJ, Garraway LA. Resistance to EGFR blockade in colorectal cancer: liquid biopsies and latent subclones. Cell Res. 2012 Jul 31. doi: 10.1038/cr.2012.115. PMID: 22847744

Oksenych V, Alt FW, Kumar V, Schwer B, Wesemann DR, Hansen E, Patel H, Su A, Guo C. Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2455-60. Epub 2012 Jan 30. PMID: 22308489

Penaranda C, Kuswanto W, Hofmann J, Kenefeck R, Narendran P, Walker LS, Bluestone JA, Abbas AK, Dooms H. IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12668-73. Epub 2012 Jun 25 PMID: 22733744

Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol. 2012 Dec 23;14(2):179-85. doi: 10.1038/ni.2509. Epub 2012 Dec 23.PMID: 23263557

Turner PE, McBride RC, Duffy S, Montville R, Wang LS, Yang YW, Lee SJ, Kim J. Evolutionary genomics of host-use in bifurcating demes of RNA virus phi-6. BMC Evol Biol. 2012 Aug 22;12(1):153. PMID: 22913547

Leskov I, Pallasch CP, Drake A, Iliopoulou BP, Souza A, Shen CH, Schweighofer CD, Abruzzo L, Frenzel LP, Wendtner CM, Hemann MT, Chen J. Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies. Oncogene. 2012 Apr 9. doi: 10.1038/onc.2012.117. [Epub ahead of print] PMID:22484426.

Meissner TB, Li A, Kobayashi KS. NLRC5: a newly discovered MHC class I transactivator (CITA). Microbes Infect. 2012 Jun;14(6):477-84. Epub 2011 Dec 22. Review. PMID: 22209772

Meissner TB*, Li A*, Liu YJ, Gagnon E, Kobayashi KS. The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity. Biochem Biophys Res Commun. 2012 Feb 24;418(4):786-91. Epub 2012 Jan 28. PMID: 22310711 (*co-first authors)

Cipolletta D, Feuerer M, Li A, Kamei N, Lee J, Shoelson SE, Benoist C, Mathis D. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature. 2012 Jun 28;486(7404):549-53. PMID: 22722857

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