Publications

2011

Choe H, Jemielty S, Abraham J, Radoshitzky SR, Farzan M. Transferrin receptor 1 in the zoonosis and pathogenesis of New World hemorrhagic fever arenaviruses. Curr Opin Microbiol 2011 Aug: 14(4):476-82. Epub 2011 Jul 30. PMID:21807555.

Agarwal I, Karumanchi SA. Preeclampsia and the Anti-Angiogenic State. Pregnancy Hypertens. 2011 Jan 1;1(1):17-21. PMID: 21709826

Shea J, Agarwala V, Philippakis AA, Maguire J, Banks E, Depristo M, Thomson B, Guiducci C, Onofrio RC, Kathiresan S, Gabriel S, Burtt NP, Daly MJ, Groop L, Altshuler D; Myocardial Infarction Genetics Consortium. Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction. Nat Genet. 2011 Jul 24;43(8):801-5. PMID: 21775993

Jordan DM, Kiezun A, Baxter SM, Agarwala V, Green RC, Murray MF, Pugh T, Lebo MS, Rehm HL, Funke BH, Sunyaev SR. Development and validation of a computational method for assessment of missense variants in hypertrophic cardiomyopathy. Am J Hum Genet. 2011 Feb 11;88(2):183-92. PMID: 21310275; PMCID:PMC3035712.

Streeck H, Kwon DS, Pyo A, Flanders M, Chevalier MF, Law K, Jülg B, Trocha K, Jolin JS, Anahtar MN, Lian J, Toth I, Brumme Z, Chang JJ, Caron T, Rodig SJ,Milner DA Jr, Piechoka-Trocha A, Kaufmann DE, Walker BD, Altfeld M. Epithelial adhesion molecules inhibit HIV-1-specific CD8+ T-cell functions. Blood. 2011 Mar 14. [Epub ahead of print] PMID: 21403126.

Henrickson SE, Agyemang AF, Garg S, Hafler JP. Integrating clinical perspectives into graduate education. Clin Immunol. 2011 Nov;141(2):228-30 PMID: 21944668

Takasawa M, Beech JS, Fryer TD, Jones PS, Ahmed T, Smith R, Aigbirhio FI, Baron JC. Single-subject statistical mapping of acute brain hypoxia in the rat following middle cerebral artery occlusion: a microPET study.Exp Neurol. 2011 Jun;229(2):251-8. Epub 2011 Feb 16. PMID: 21335004

Xu D, Allsop SA, Witherspoon SM, Snider JL, Yeh JJ, Fiordalisi JJ, White CD, Williams D, Cox AD, Baines AT. The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells. Carcinogenesis. 2011 Apr;32(4):488-95. Epub 2011 Jan 24. PMID: 21262926

Allsop SA, Erstad DJ, Brook K, Bhai SF, Cohen JM, Dimitrakoff JD. The DABBEC phenotyping system: towards a mechanistic understanding of CP/CPPS. Nat Rev Urol. 2011 Feb;8(2):107-13. Epub 2011 Jan 18. Review. PubMed PMID: 21243018.

Mahal BA, Cohen JM, Allsop SA, Moore JB, Bhai SF, Inverso G, Dimitrakoff JD. The role of phenotyping in chronic prostatitis/chronic pelvic pain syndrome. Curr Urol Rep. 2011 Aug;12(4):297-303. doi: 10.1007/s11934-011-0196-y. Review. PMID: 21533747

Walrant A, Correia I, Jiao CY, Lequin O, Bent EH, Goasdoué N, Lacombe C, Chassaing G, Sagan S, Alves ID. Different membrane behaviour and cellular uptake of three basic arginine-rich peptides. Biochim Biophys Acta. 2011 Jan;1808(1):382-93. Epub 2010 Oct 13. PMID: 20920465

Bick, A., Ristenpart, W.D. , van Nierop, E. , Stone., H.A. (April 2011) "Mechanical Inhibition of Foam Formation via a Rotating Nozzle" Journal of Fluids Engineering. J. Fluids Eng. -- April 2011 -- Volume 133, Issue 4, 044503 (3 pages) doi:10.1115/1.4003987

Wheeldon I, Farhadi A, Bick AG, Jabbari E, Khademhosseini A. Nanoscale tissue engineering: spatial control over cell-materials interactions. Nanotechnology. 2011 May 27;22(21):212001. Epub 2011 Mar 31. PubMed PMID: 21451238.

Wheeldon I, Farhadi A, Bick AG, Jabbari E, Khademhosseini A. Nanoscale tissue engineering: spatial control over cell-materials interactions. Nanotechnology.2011 May 27;22(21):212001. Epub 2011 Mar 31.PMID: 21451238.

Pan S, Wang S, Utama B, Huang L, Blok N, Estes MK, Moremen KW, Sifers RN. Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system. Mol Biol Cell. 2011 Aug 15;22(16):2810-22. Epub 2011 Jun 22.PMID: 21697506 PMCID:PMC3154878

Aster JC, Bodnar N, Xu L, Karnell F, Milholland JM, Maillard I, Histen G, Nam Y, Blacklow SC, Pear WS. Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation. PLoS One. 2011;6(10):e25645. Epub 2011 Oct 13. PMID: 22022427

Bolar DS, Rosen BR, Sorensen AG, Adalsteinsson E. QUantitative Imaging of eXtraction of Oxygen and TIssue Consumption (QUIXOTIC) using venular- targeted velocity selective spin labeling. Magn Reson Med. 2011 Dec;66(6):1550-62. doi: 10.1002/mrm.22946. Epub 2011 Jun 14.PMID: 21674615

Fan AP, Benner T, Bolar DS, Rosen BR, Adalsteinsson E. Phase-based regional oxygen metabolism (PROM) using MRI.Magn Reson Med. 2011 Jun 28. doi: 10.1002/mrm.23050. [Epub ahead of print]. PMID: 21713981

Bryan AW Jr, Starner-Kreinbrink JL, Hosur R, Clark PL, Berger B. Structure-based prediction reveals capping motifs that inhibit β-helix aggregation. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11099-104. Epub 2011 Jun 17. PMID: 21685332

Bryan AW Jr, O'Donnell CW, Menke M, Cowen LJ, Lindquist S, Berger B.STITCHER: Dynamic assembly of likely amyloid and prion β-structures from secondary structure predictions. Proteins. 2011 Sep 23. doi: 10.1002/prot.23203. [Epub ahead of print] PMID: 22095906

Guan Z, Buhl LK, Quinn WG, Littleton JT. Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. Learn Mem. 2011 Mar 21;18(4):191-206. doi: 10.1101/lm.2027111. Print 2011. PMID: 21422168;PMCID: PMC3072773.

Rodal AA, Blunk AD, Akbergenova Y, Jorquera RA, Buhl LK, Littleton JT. A presynaptic endosomal trafficking pathway controls synaptic growth signaling. J Cell Biol. 2011 Apr 4;193(1):201-17. PMID: 21464232.

Pietrusinski M, Unluhisarcikli O, Mavroidis C, Cajigas I, Bonato P. Design of human - Machine interface and altering of pelvic obliquity with RGR Trainer. IEEE Int Conf Rehabil Robot. 2011 Jun;2011:1-6. PMID: 22275693.

Paz AC, Kojima K, Iwasaki K, Ross JD, Canseco JA, Umezu M, Vacanti CA. Tissue Engineered Trachea Using Decellularized Aorta. J Bioeng and Biomed Sci. S2:001, 2011. 

Canver MC. The last summer of your life. IEEE Pulse. 2011 Nov;2(6):10. No abstract available. PMID:22250334

Canver MC. Medicine and memorization. IEEE Pulse. 2011 Mar-Apr;2(2):9-10. No abstract available.PMID:21805728

Lee KW, Chen W, Junn E, Im JY, Grosso H, Sonsalla PK, Feng X, Ray N, Fernandez JR, Chao Y, Masliah E, Voronkov M, Braithwaite SP, Stock JB, Mouradian MM. Enhanced phosphatase activity attenuates α-Synucleinopathy in a mouse model. J Neurosci. 2011 May 11;31(19):6963-71. PMID: 21562258.

Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 2011 Jul 14. doi: 10.1038/nature10350. [Epub ahead of print] PubMed PMID: 21760589.

Jonas K*, Chen YE*, Laub MT. Modularity of the bacterial cell cycle enables independent spatial and temporal control of DNA replication..Curr Biol. 2011 Jul 12;21(13):1092-101. Epub 2011 Jun 16. PMID: 21683595

Chen YE*, Tropini C*, Jonas K, Tsokos CG, Huang KC, Laub MT. Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium. Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1052-7. Epub 2010 Dec 29. PMID: 21191097

Fioravante D, Chu Y, Myoga MH, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held.
Neuron. 2011 Jun 9;70(5):1005-19.PMID: 21658591

Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME.Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 2011 Oct 6;72(1):72-85.PMID: 21982370

Goffin D, Allen M, Zhang L, Amorim M, Wang IT, Reyes AR, Mercado-Berton A, Ong C, Cohen S, Hu L, Blendy JA, Carlson GC, Siegel SJ, Greenberg ME, Zhou Z.Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses. Nat Neurosci. 2011 Nov 27;15(2):274-83. doi: 10.1038/nn.2997.PMID: 22119903

Comeaux CA, Coleman BI, Bei AK, Whitehurst N, Duraisingh MT. Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth. Mol Microbiol. 2011 Apr;80(2):378-90. doi: 10.1111/j.1365-2958.2011.07572.x. Epub 2011 Mar 7. PMID: 21320181

Comeaux CA, Coleman BI, Bei AK, Whitehurst N, Duraisingh MT. Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth. Mol Microbiol. 2011 Apr;80(2):378-90. doi:10.1111/j.1365-2958.2011.07572.x. Epub 2011 Mar 7. PubMed PMID: 21320181.

Ellwood-Yen K, Keilhack H, Kunii K, Dolinski B, Connor Y, Hu K, Nagashima K, O'Hare E, Erkul Y, Di Bacco A, Gargano D, Shomer NH, Angagaw M, Leccese E, Andrade P, Hurd M, Shin MK, Vogt TF, Northrup A, Bobkova EV, Kasibhatla S, Bronson RT, Scott ML, Draetta G, Richon V, Kohl N, Blume-Jensen P, Andersen JN, Kraus M. PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models. Cancer Res. 2011 Apr 15;71(8):3052-65.PMID: 21493594

Coulter ME, Miller DT, Harris DJ, Hawley P, Picker J, Roberts AE, Sobeih MM, Irons M. Chromosomal microarray testing influences medical management. Genet Med. 2011 Sep;13(9):770-6. PMID: 21716121.

Fell GL, Munson AM, Croston MA, Rosenwald AG.Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. G3 (Bethesda). 2011 Jun;1(1):43-56. Epub 2011 Jun 1. PMID: 22384317

Franses JW, Baker AB, Chitalia VC, Edelman ER. Stromal endothelial cells directly influence cancer progression. Sci Transl Med. 2011 Jan 19;3(66):66ra5.PMID: 21248315; PMCID: PMC3076139.

Franses, JW, Edelman ER. The Evolution of Endothelial Regulatory Paradigms in Cancer Biology and Vascular Repair. Cancer Res. 2011 Dec 15, 71(24). PMID: 221444472.

Chitalia VC, Murikipudi S, Indolfi L, Rabadi L, Valdez R, Franses JW, Edelman ER. Matrix-embedded endothelial cells are protected from the uremic milieu.
Nephrol Dial Transplant. 2011 Dec;26(12):3858-65. Epub 2011 Jul 27. PMID: 21795755

Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, Jaenisch R, Schultz PG.Angew. Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Chem Int Ed Engl. 2011 Jun 14;50(25):5734-6. doi: 10.1002/anie.201101042. Epub 2011 May 5. PMID: 21547985

Garg S, Sharma M, Ung C, Tuli A, Barral DC, Hava DL, Veerapen N, Besra GS, Hacohen N, Brenner MB. Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b. Immunity. 2011 Aug 26;35(2):182-93. Epub 2011 Jul 28. PMID: 21802320

Kolandaivelu K, Swaminathan R, Gibson WJ, Kolachalama VB, Nguyen-Ehrenreich KL, Giddings VL, Coleman L, Wong GK, Edelman ER. Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings. Circulation. 2011 Apr 5;123(13):1400-9. Epub 2011 Mar 21. PubMed PMID: 21422389.

Gonzalez Castro LN, Monsen CB, Smith MA. The binding of learning to action in motor adaptation. PLoS Comput Biol. 2011 Jun;7(6):e1002052. doi: 10.1371/journal.pcbi.1002052. Epub 2011 Jun 23. PMID: 21731476

Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. J Clin Invest. 2011 Nov;121(11):4383-92. doi: 10.1172/JCI59041. Epub 2011 Oct 3. PMID: 21965325

Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. J Clin Invest. 2012 Jan 3;122(1):91-106. doi: 10.1172/JCI59466. Epub 2011 Dec 1. PMID: 22133875

Dougan SK, Hu CC, Paquet ME, Greenblatt MB, Kim J, Lilley BN, Watson N, Ploegh HL. Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes. Mol Cell Biol. 2011 Mar;31(6):1145-59. Epub 2011 Jan 10. PMID: 21220515

Reshef DN, Reshef YA, Finucane HK, Grossman SR, McVean G, Turnbaugh PJ, Lander ES, Mitzenmacher M, Sabeti PC. Detecting novel associations in large data sets. Science. 2011 Dec 16;334(6062):1518-24. PMID: 22174245

Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA Jr, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011 Apr;7(4):e1001383. Epub 2011 Apr 21. PMID: 21533027

Saadi I, Alkuraya FS, Gisselbrecht SS, Goessling W, Cavallesco R, Turbe-Doan A, Petrin AL, Harris J, Siddiqui U, Grix AW Jr, Hove HD, Leboulch P, Glover TW, Morton CC, Richieri-Costa A, Murray JC, Erickson RP, Maas RL.Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. Am J Hum Genet. 2011 Jul 15;89(1):44-55. Epub 2011 Jun 23. PMID: 21703590

Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, Donahue RE, North TE.Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 2011 Apr 8;8(4):445-58. PMID: 21474107

Textor J, Peixoto A, Henrickson SE, Sinn M, von Andrian UH, Westermann J.Defining the quantitative limits of intravital two-photon lymphocyte tracking. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12401-6. Epub 2011 Jul 6. PMID:21734152

Henrickson SE, Agyemang AF, Garg S, Hafler JP. Integrating clinical perspectives into graduate education.Clin Immunol. 2011 Nov;141(2):228-30. Epub 2011 Sep 5. No abstract available. PMID:21944668

Christodoulou DC, Gorham JM, Kawana M, DePalma SR, Herman DS, Wakimoto H. Quantification of gene transcripts with deep sequencing analysis of gene expression (DSAGE) using 1 to 2 µg total RNA. Curr Protoc Mol Biol. 2011 Jan;Chapter 25:Unit25B.9. PMID: 2122563

Christodoulou DC, Gorham JM, Herman DS, Seidman JG. Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease. Curr Protoc Mol Biol. 2011 Apr;Chapter 4:Unit4.12. PMID:21472699

Holleboom AG, Karlsson H, Lin RS, Beres TM, Sierts JA, Herman DS, Stroes ES, Aerts JM, Kastelein JJ, Motazacker MM, Dallinga-Thie GM, Levels JH, Zwinderman AH, Seidman JG, Seidman CE, Ljunggren S, Lefeber DJ, Morava E, Wevers RA, Fritz TA, Tabak LA, Lindahl M, Hovingh GK, Kuivenhoven JA Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man. Cell Metab. 2011 Dec 7;14(6):811-8. PMID:22152306

Pathania S, Nguyen J, Hill SJ, Scully R, Adelmant GO, Marto JA, Feunteun J, Livingston DM. BRCA1 is required for postreplication repair after UV-induced DNA damage. Mol Cell. 2011 Oct 21;44(2):235-51. Epub 2011 Sep 29. PMID: 21963239

Hollenhorst MA, Ntai I, Badet B, Kelleher NL, Walsh CT. A head-to-head comparison of eneamide and epoxyamide inhibitors of glucosamine-6-phosphate synthase from the dapdiamide biosynthetic pathway. Biochemistry. 2011 May 17;50(19):3859-61. Epub 2011 Apr 26. PMID: 21520904

Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 2011 Aug 18;476(7360):346-50. doi: 10.1038/nature10350. PMID: 21760589

Hsu PP, Kang SA, Rameseder J, Zhang Y, Ottina KA, Lim D, Peterson TR, Choi Y, Gray NS, Yaffe MB, Marto JA, Sabatini DM. The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science. 2011 Jun 10;332(6035):1317-22. PMID: 21659604

Lindquist RA, Ottina KA, Wheeler DB, Hsu PP, Thoreen CC, Guertin DA, Ali SM, Sengupta S, Shaul YD, Lamprecht MR, Madden KL, Papallo AR, Jones TR, Sabatini DM, Carpenter AE. Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling. Genome Res. 2011 Mar;21(3):433-46. Epub 2011 Jan 14. PMID: 21239477Hung YP, Albeck JG, Tantama M, Yellen G. Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor. Cell Metab. 2011 Oct 5;14(4):545-54. PMID: 21982714

Hu X, Kim H, Stahl E, Plenge R, Daly M, Raychaudhuri S. Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets. Am J Hum Genet. 2011 Oct 7;89(4):496-506. doi: 10.1016/j.ajhg.2011.09.002. Epub 2011 Sep 29. Erratum in: Am J Hum Genet. 2011 Nov 11;89(5):682. PMID: 21963258

Tantama M, Hung YP, Yellen G. Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor. J Am Chem Soc. 2011 Jul 6;133(26):10034-7. Epub 2011 Jun 9. PMID: 21631110

Huynh MA, Ikeuchi Y, Netherton S, de la Torre-Ubieta L, Kanadia R, Stegmüller J, Cepko C, Bonni S, Bonni A. An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron. 2011 Mar 10;69(5):930-44. PMID: 21382553; PMCID: PMC3073069.

Hwang, KL and ME Coulter, Reproduction, In: First Aid for the Basic Sciences, Organ Systems, T Le ed., McGraw-Hill, 2011.

Tao Le, Kendall Krause, Elizabeth Halvorson, and William Hwang. (2011). First Aid for the Basic Sciences: Organ Systems, 2e. New York, NY: McGraw-HILL (ISBN 978-0071743952, 858 pages).

Unal E, Kinde B, Amon A. Gametogenesis eliminates age-induced cellular damage and resets life span in yeast. Science. 2011 Jun 24;332(6037):1554-7. PMID: 21700873

Koffie RM, Farrar CT, Saidi LJ, William CM, Hyman BT, Spires-Jones TL. Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18837-42. Epub 2011 Nov 7.
PMID: 22065785

Koffie RM, Hyman BT, Spires-Jones TL. Alzheimer's disease: synapses gone cold. Mol Neurodegener. 2011 Aug 26;6(1):63. PMID: 21871088

Kopeikina KJ, Carlson GA, Pitstick R, Ludvigson AE, Peters A, Luebke JI, Koffie RM, Frosch MP, Hyman BT, Spires-Jones TL. Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. Am J Pathol. 2011 Oct;179(4):2071-82. Epub 2011 Aug 18. PMID: 21854751

Spires-Jones TL, Kopeikina KJ, Koffie RM, de Calignon A, Hyman BT. Are tangles as toxic as they look? J Mol Neurosci. 2011 Nov;45(3):438-44. Epub 2011 Jun 3. Review. Erratum in: J Mol Neurosci. 2011 Nov 45(3):742. PMID: 21638071

Baish JW, Stylianopoulos T, Lanning RM, Kamoun WS, Fukumura D, Munn LL, Jain RK .Scaling rules for diffusive drug delivery in tumor and normal tissues. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1799-803. Epub 2011 Jan 11.PMID:21224417

Lin Y, Zhang L, Cai AX, Lee M, Zhang W, Neuberg D, Canning CM, Soiffer RJ, Alyea EP, Ritz J, Hacohen N, Means TK, Wu CJ. Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans. J Clin Invest. 2011 Apr;121(4):1574-84. doi: 10.1172/JCI44581. Epub 2011 Mar 14. PMID: 21403403

Drake AC, Khoury M, Leskov I, Iliopoulou BP, Fragoso M, Lodish H, Chen J. Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rγ-/- (NSG) mice. PLoS One. 2011 Apr 29;6(4):e18382. PMID: 21559522

Mukherji EH, Bauer LK, Leskov I, Januzzi JL, Tanev KS Safety of antipsychotics in the setting of QTc prolongation: the utility of the JT index. Am J Psychiatry. 2011 Sep;168(9):990-1. No abstract available. PMID: 21890808

Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, Dombkowski D, Evans JW, Liefeld T, Smutko JS, Chen J, Friedman N, Young RA, Golub TR, Regev A, Ebert BL. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell. 2011 Jan 21;144(2):296-309. PMID: 21241896

Khoury M, Drake A, Chen Q, Dong D, Leskov I, Fragoso MF, Li Y, Iliopoulou BP, Hwang W, Lodish HF, Chen J. Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential. Stem Cells Dev. 2011 Aug;20(8):1371-81. Epub 2011 Jan 31. PMID: 21142526

Bassett EK, Hoganson DM, Lo JH, Penson EJ, Vacanti JP. Influence of vascular network design on gas transfer in lung assist device technology. ASAIO J. 2011 Nov-Dec;57(6):533-8.PMID: 22036722

Manne J, Maciag K. Neglected tropical diseases and the HIV prevention agenda. Lancet. 2011 Dec 17;378(9809):2069-70. No abstract available. PMID:22177509

Mengwasser KE, Bryant CE, Gay NJ, Gangloff M. LPS ligand and culture additives improve production of monomeric MD-1 and 2 in Pichia pastoris by decreasing aggregation and intermolecular disulfide bonding. Protein Expr Purif. 2011 Apr;76(2):173-83. Epub 2010 Dec 2. PMID: 21130168

Cheung HW, Cowley GS, Weir BA, Boehm JS, Rusin S, Scott JA, East A, Ali LD, Lizotte PH, Wong TC, Jiang G, Hsiao J, Mermel CH, Getz G, Barretina J, Gopal S, Tamayo P, Gould J, Tsherniak A, Stransky N, Luo B, Ren Y, Drapkin R, Bhatia SN, Mesirov JP, Garraway LA, Meyerson M, Lander ES, Root DE, Hahn WC. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12372-7. Epub 2011 Jul 11. PMID: 21746896

Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A,Johnson LA, Beroukhim R, Mermel CH, Loda M, Ait-Si-Ali S, Garraway LA, Young RA, Zon LI. The histone methyltransferase SETDB1 is recurrently amplified in melanomaand accelerates its onset. Nature. 2011 Mar 24;471(7339):513-7 PMID: 21430779.

Mermel CH, Schumacher SE, Hill B, Meyerson ML, Beroukhim R, Getz G. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol. 2011;12(4):R41. Epub 2011 Apr 28. PMID: 21527027

Dutt A, Ramos AH, Hammerman PS, Mermel C, Cho J, Sharifnia T, Chande A, Tanaka KE, Stransky N, Greulich H, Gray NS, Meyerson M. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PLoS One. 2011;6(6):e20351. Epub 2011 Jun 7. PMID: 21666749

Mitra D, Robinson KC, Fisher DE. Melanoma and viagra: an unexpected connection. Pigment Cell Melanoma Res. 2011 Feb;24(1):16-8. No abstract available.  PMID: 21290790

Olurinde MO, Shen CH, Drake A, Bai A, Chen J. Persistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independent. Cell Mol Immunol. 2011 Sep;8(5):415-23. doi: 10.1038/cmi.2011.18. Epub 2011 Jun 13. PMID: 21666707

Pattanayak V, Ramirez CL, Joung JK, Liu DR. Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection. Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670. PMID: 21822273

Schinzel RT, Ahfeldt T, Lau FH, Lee YK, Cowley A, Shen T, Peters D, Lum DH, Cowan CA Efficient culturing and genetic manipulation of human pluripotent stem cells. PLoS One. 2011;6(12):e27495. Epub 2011 Dec 15. PMID: 22194785

Medici D, Potenta S, Kalluri R.Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling.Biochem J. 2011 Aug 1;437(3):515-20.PMID:21585337

Puram SV, Riccio A, Koirala S, Ikeuchi Y, Kim AH, Corfas G, Bonni A. A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Genes Dev. 2011 Dec 15;25(24):2659-73. Epub 2011 Dec 1.
PMID: 22135323

Puram SV, Kim AH, Ikeuchi Y, Wilson-Grady JT, Merdes A, Gygi SP, Bonni A. A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat Neurosci. 2011 Jul 3;14(8):973-83. doi: 10.1038/nn.2857. PMID: 21725312

Puram SV, Bonni A. Novel functions for the anaphase-promoting complex in neurobiology. Semin Cell Dev Biol. 2011 Aug;22(6):586-94. Epub 2011 Mar 23. Review. PMID: 21439392

Chen LL, Madhavan R, Rapoport BI, Anderson WS. A method for real-time cortical oscillation detection and phase-locked stimulation. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:3087-90. PMID:22254992

Zheng GX, Ravi A, Gould GM, Burge CB, Sharp PA.Genome-wide impact of a recently expanded microRNA cluster in mouse. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15804-9. Epub 2011 Sep 12.PMID:21911408

Zheng GX, Ravi A, Calabrese JM, Medeiros LA, Kirak O, Dennis LM, Jaenisch R, Burge CB, Sharp PA. A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells. PLoS Genet. 2011 May;7(5):e1002054. Epub 2011 May 5. PMID:21573140

Cheung HW, Cowley GS, Weir BA, Boehm JS, Rusin S, Scott JA, East A, Ali LD, Lizotte PH, Wong TC, Jiang G, Hsiao J, Mermel CH, Getz G, Barretina J, Gopal S, Tamayo P, Gould J, Tsherniak A, Stransky N, Luo B, Ren Y, Drapkin R, Bhatia SN, Mesirov JP, Garraway LA, Meyerson M, Lander ES, Root DE, Hahn WC. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12372-7. Epub 2011 Jul 11. PMID:21746896

Goldberg MS, Xing D, Ren Y, Orsulic S, Bhatia SN, Sharp PA. Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):745-50. Epub 2010 Dec 27. PMID:21187397

Reshef DN, Reshef YA, Finucane HK, Grossman SR, McVean G, Turnbaugh PJ, Lander ES, Mitzenmacher M, Sabeti PC. Detecting novel associations in large data sets. Science. 2011 Dec 16;334(6062):1518-24. PMID: 22174245

Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C, Abecasis GR, Barrett JC, Behrens T, Cho J, De Jager PL, Elder JT, Graham RR, Gregersen P, Klareskog L, Siminovitch KA, van Heel DA, Wijmenga C, Worthington J, Todd JA, Hafler DA, Rich SS, Daly MJ; FOCiS Network of Consortia. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet. 2011 Aug;7(8):e1002254. Epub 2011 Aug 10. PMID: 21852963

Rossin E, Lin TI, Ho HJ, Mentzer SJ, Pyne S. A framework for analytical characterization of monoclonal antibodies based on reactivity profiles in different tissues. Bioinformatics. 2011 Oct 1;27(19):2746-53. Epub 2011 Aug 16. PMID: 21846734

Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, et al. Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat Genet. 2011 Sep 18;43(10):969-76. doi: 10.1038/ng.940. PMID: 21926974

Rossin EJ, Lage K, Raychaudhuri S, Xavier RJ, Tatar D, Benita Y; International Inflammatory Bowel Disease Genetics Constortium, Cotsapas C, Daly MJ. Proteinsencoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet. 2011 Jan 13;7(1):e1001273. PMID: 21249183;PMCID: PMC3020935.

Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. J Cell Biol. 2011 Mar 7;192(5):825-38. Epub 2011 Feb 28. PMID: 21357747; PubMed Central PMCID: PMC3051819.

Giusti-Rodríguez P, Gao J, Gräff J, Rei D, Soda T, Tsai LH. Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1). J Neurosci. 2011 Nov 2;31(44):15751-6. PMID: 22049418

Song Z, Safran DG, Landon BE, He Y, Ellis RP, Mechanic RE, Day MP, Chernew ME., Health care spending and quality in year 1 of the alternative quality contract. N Engl J Med. 2011 Sep 8;365(10):909-18. Epub 2011 Jul 13. PMID: 21751900

Shankar GM, Welzel AT, McDonald JM, Selkoe DJ, Walsh DM. Isolation of low-n amyloid ß-protein oligomers from cultured cells, CSF, and brain. Methods Mol Biol. 2011;670:33-44. PMID: 20967581

Subtelny AO, Hartman MC, Szostak JW Optimal codon choice can improve the efficiency and fidelity of N-methyl amino acid incorporation into peptides by in-vitro translation. Angew Chem Int Ed Engl. 2011 Mar 28;50(14):3164-7. doi: 10.1002/anie.201007686. Epub 2011 Mar 4. No abstract available. PMID: 21381166

Mantell JE, West BS, Sue K, Hoffman S, Exner TM, Kelvin E, Stein ZA. Health care providers: a missing link in understanding acceptability of the female condom. AIDS Educ Prev. 2011 Feb;23(1):65-77. PMID: 21341961

Tsokos CG, Perchuk BS, Laub MT. A Dynamic Complex of Signaling Proteins Uses Polar Localization to Regulate Cell-Fate Asymmetry in Caulobacter crescentus. Dev Cell. 2011 Mar 15;20(3):329-41.PMID: 21397844; PMCID: PMC3068846.

Chen YE, Tropini C, Jonas K, Tsokos CG, Huang KC, Laub MT. Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium. Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1052-7. Epub 2010 Dec 29. PMID: 21191097

van Schaik KD, Thompson SC. Indigenous beliefs about biomedical and bush medicine treatment efficacy for Indigenous cancer patients: a review of the literature. Intern Med J. 2012 Feb;42(2):184-91. doi: 10.1111/j.1445-5994.2011.02598.x. PMID:21981135

van Schaik KD. A piece of my mind. "Taking" a history. JAMA. 2010 Sep 15;304(11):1159-60. No abstract available.  PMID:20841524

Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, Sabatini DM. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. Science. 2011 Nov 4;334(6056):678-83. PMID: 22053050

Wheeler LA, Trifonova R, Vrbanac V, Basar E, McKernan S, Xu Z, Seung E, Deruaz M, Dudek T, Einarsson JI, Yang L, Allen TM, Luster AD, Tager AM, Dykxhoorn DM, Lieberman J. Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras. J Clin Invest. 2011 Jun;121(6):2401-12. doi: 10.1172/JCI45876. Epub 2011 May 16. PMID: 21576818

Yan N, O'Day E, Wheeler LA, Engelman A, Lieberman J. HIV DNA is heavily uracilated, which protects it from autointegration. Proc Natl Acad Sci U S A. 2011 May 31;108(22):9244-9. Epub 2011 May 16. PMID: 21576478

Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 2011 Mar 10;69(5):893-905. PMID: 21382550