Publications

2008

Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, McGrath JP, Protopopova M, Ivanova E, Zhang J, Feng B, Tsao MS, Redston M, Protopopov A, Xiao Y, Futreal PA, Hahn WC, Klimstra DS, Chin L, DePinho RA. Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19372-7. Epub 2008 Dec 2. PMID: 19050074

Chen Y, Aguirre AD, Hsiung PL, Huang SW, Mashimo H, Schmitt JM, Fujimoto JG. Effects of axial resolution improvement on optical coherence tomography (OCT) imaging of gastrointestinal tissues.Opt Express. 2008 Feb 18;16(4):2469-85. PMID: 18542326

Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR. Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab. 2008 Feb;7(2):125-34

Yang XH, Richardson AL, Torres-Arzayus MI, Zhou P, Sharma C, Kazarov AR, Andzelm MM, Strominger JL, Brown M, Hemler ME. CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization.Cancer Res. 2008 May 1;68(9):3204-13.

D'Alise AM, Auyeung V, Feuerer M, Nishio J, Fontenot J, Benoist C, Mathis D. The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19857-62. Epub 2008 Dec 10.

Leader B, Baca QJ, Golan DE. Protein therapeutics: a summary and pharmacological classification. Nat Rev Drug Discov. 2008 Jan;7(1):21-39. Review.

Zaidi T, Bajmoczi M, Zaidi T, Golan DE, Pier GB.Disruption of CFTR-dependent lipid rafts reduces bacterial levels and corneal disease in a murine model of Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1000-9.

Balakrishnan B, Dooley J, Kopia G, Edelman ER. Thrombus causes fluctuations in arterial drug delivery from intravascular stents.J Control Release. 2008 Nov 12;131(3):173-80. Epub 2008 Jul 25.PMID: 18713645

Miyata S, Begun J, Troemel ER, Ausubel FM. DAF-16-Dependent Suppression of Immunity During Reproduction in Caenorhabditis elegans.Genetics. 2008 Feb;178(2):903-18. Epub 2008 Feb 1.

Bortnick RA, Gaufberg E. Injustice. Med Educ. 2008 Nov;42(11):1108-9. PMID: 19141010

Aoki H, Oman CM, Buckland DA, Natapoff A. Desktop-VR system for preflight 3D navigation training. Acta Astronautica. 2008 Oct-Nov; 63 (7-10):841-847 doi:10.1016/j.actaastro.2007.11.001

Chang HH, Hemberg M, Barahona M, Ingber DE, Huang S. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature. 2008 May 22;453(7194):544-547.

Chretien YR. Time to defibrillation after in-hospital cardiac arrest. N Engl J Med. 2008 Apr 10;358(15):1631.

Cochran DM, Yock TI, Adams JA, Tarbell NJ. Radiation dose to the lens during craniospinal irradiation-an improvement in proton radiotherapy technique.Int J Radiat Oncol Biol Phys. 2008 Apr 1;70(5):1336-42. Epub 2007 Oct 29.PMID: 18029111

Cohen S, Greenberg ME. Communication Between the Synapse and Nucleus in Neuronal Development, Plasticity, and Disease. Annu Rev Cell Dev Biol. 2008 Jul 10. [Epub ahead of print]

Cohen S, Zhou Z, Greenberg ME. Medicine. Activating a repressor. Science. 2008 May 30;320(5880):1172-3. No abstract available.

Militello KT, Refour P, Comeaux CA, Duraisingh MT. Antisense RNA and RNAi in protozoan parasites: working hard or hardly working? Mol Biochem Parasitol. 2008 Feb;157(2):117-26. Epub 2007 Oct 18.

Chiara Manzini M, Gleason D, Chang BS, Sean Hill R, Barry BJ, Partlow JN, Poduri A, Currier S, Galvin-Parton P, Shapiro LR, Schmidt K, Davis JG, Basel-Vanagaite L, Seidahmed MZ, Salih MA, Dobyns WB, Walsh CA. Ethnically diverse causes of Walker-Warburg syndrome (WWS): FCMD mutations are a more common cause of WWS outside of the Middle East.Hum Mutat. 2008 Nov;29(11):E231-41.PMID: 18752264

Tonna S, Dandapani SV, Uscinski A, Appel GB, Schlöndorff JS, Zhang K, Denker BM, Pollak MR. Functional genetic variation in aminopeptidase A (ENPEP): lack of clear association with focal and segmental glomerulosclerosis (FSGS). Gene. 2008 Feb 29;410(1):44-52.

Henderson JM, Al-Waheeb S, Weins A, Dandapani SV, Pollak MR. Mice with altered alpha-actinin-4 expression have distinct morphologic patterns of glomerular disease. Kidney Int. 2008 Mar;73(6):741-50. Epub 2008 Jan 9.

Immune Therapy for Cancer. Dougan M, Dranoff G. Annu Rev Immunol. 2008 Nov 13. [Epub ahead of print] PMID: 19007331

Dougan M, Dranoff G. Inciting inflammation: the RAGE about tumor promotion. J Exp Med. 2008 Feb 18;205(2):267-70. Epub 2008 Feb 11.

Jensen P*, Farago AF*, Awatramani RB*, Scott M, Deneris E, Dymecki SM. Redefining the central serotonergic system based on genetic lineage. Nature Neurosci. 2008 Apr;11(4):417-9. Epub 2008 Mar 16 . [*equal contribution]

Friedman RC, Farh KK, Burge CB, Bartel D. Most mammalian mRNAs are conserved targets of microRNAs.Genome Res. 2008 Oct 27. [Epub ahead of print] PMID: 18955434

Heng TS, Painter MW; Immunological Genome Project Consortium (Elpek K, Lukacs-Kornek V, Mauermann N, Turley SJ, Koller D, Kim FS, Wagers AJ, Asinovski N, Davis S, Fassett M, Feuerer M, Gray DH, Haxhinasto S, Hill JA, Hyatt G, Laplace C, Leatherbee K, Mathis D, Benoist C, Jianu R, Laidlaw DH, Best JA, Knell J, Goldrath AW, Jarjoura J, Sun JC, Zhu Y, Lanier LL, Ergun A, Li Z, Collins JJ, Shinton SA, Hardy RR, Friedline R, Sylvia K, Kang J.) The Immunological Genome Project: networks of gene expression in immune cells.Nat Immunol. 2008 Oct;9(10):1091-4.PMID: 18800157

Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R.Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell. 2008 Aug 7;3(2):132-5. N

Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat Biotechnol. 2008 Aug;26(8):916-24. Epub 2008 Jul 1.

Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency.Cell. 2008 Apr 18;133(2):250-64. Erratum in: Cell. 2008 Jul 25;134(2):365.

Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R.Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell. 2008 Feb 7;2(2):151-9

Barral DC, Cavallari M, McCormick PJ, Garg S, Magee AI, Bonifacino JS, De Libero G, Brenner MB. CD1a and MHC Class I Follow a Similar Endocytic Recycling Pathway. Traffic. 2008 Jun 28. [Epub ahead of print]

He R, Oyoshi MK, Garibyan L, Kumar L, Ziegler SF, Geha RS. TSLP acts on infiltrating effector T cells to drive allergic skin inflammation.Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11875-80. Epub 2008 Aug 18.PMID: 18711124

Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses. Clin Vaccine Immunol. 2008. 15(4):691-6.

Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, van Rooijen N, Hovav AH, Letvin NL. CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T cell immune responses.Blood. 2008 Sep 10. [Epub ahead of print] PMID: 18784371

Hafler BP, Choi MY, Shivdasani RA, Rowitch DH. Expression and function of Nkx6.3 in vertebrate hindbrain. Brain Res. 2008 Jul 30;1222:42-50. Epub 2008 May 6.PMID: 18586225

Trimarchi JM, Harpavat S, Billings NA, Cepko CL. Thyroid hormone components are expressed in three sequential waves during development of the chick retina. BMC Dev Biol. 2008 Oct 14;8:101. PMID: 18854032

Zheng H, Jin B, Henrickson SE, Perelson AS, von Andrian UH, Chakraborty AK. How antigen quantity and quality determine T-cell decisions in lymphoid tissue. Mol Cell Biol. 2008 Jun;28(12):4040-51. Epub 2008 Apr 21.

Henrickson SE, Mempel TR, Mazo IB, Artyomov MN, Zheng H, Liu B, Flynn M, Senman B, Junt T, Wong HC, Chakraborty AK, UH von Andrian.  T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation.  Nat. Immunol. (2008) 9: 282-291.

Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn M, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH. In vivo imaging of T cell priming.Sci Signal. 2008 Mar 25;1(12):pt2.PMID: 18364513

Hill SJ, Berkowitz R, Granter SR, Hirsch MS.  Pagetoid Lesions of the Vulva: A Collision Between Malignant Melanoma and Extramammary Paget Disease.  Int J Gynecol Pathol. 2008 Apr;27(2):292-296.

Lyckman AW, Horng S, Leamey CA, Tropea D, Watakabe A, Van Wart A, McCurry C, Yamamori T, Sur M. Gene expression patterns in visual cortex during the critical period: synaptic stabilization and reversal by visual deprivation.Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9409-14. Epub 2008 Jul 7.PMID: 18606990

Hsu PP, Sabatini DM. Cancer cell metabolism: Warburg and beyond.Cell. 2008 Sep 5;134(5):703-7.PMID: 18775299

Domínguez I, Crippa S, Thayer SP, Hung YP, Ferrone CR, Warshaw AL, Fernández-Del Castillo C. Preoperative platelet count and survival prognosis in resected pancreatic ductal adenocarcinoma. World J Surg. 2008 Jun;32(6):1051-6. PMID: 18224462

Sarker KP, Kataoka H, Chan A, Netherton SJ, Pot I, Huynh MA, Feng X, Bonni A, Riabowol K, Bonni S. ING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cells. J Biol Chem. 2008 May 9;283(19):13269-79. Epub 2008 Mar 11.

Stegmüller J, Huynh MA, Yuan Z, Konishi Y, Bonni A., TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis. J Neurosci. 2008 Feb 20;28(8):1961-9.

King KR, Wang S, Jayaraman A, Yarmush ML, Toner M. Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab Chip. 2008 Jan;8(1):107-16. Epub 2007 Nov 29. PMID: 18094768

Ma YC, Song MR, Park JP, Henry Ho HY, Hu L, Kurtev MV, Zieg J, Ma Q, Pfaff SL, Greenberg ME. Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron. 2008 Apr 10;58(1):65-77. Review.

Roesch K, Jadhav AP, Trimarchi JM, Stadler MB, Roska B, Sun BB, Cepko CL. The transcriptome of retinal Müller glial cells.J Comp Neurol. 2008 Jul 10;509(2):225-38.PMID: 18465787

Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.J Neurosci. 2008 May 7;28(19):4878-87.PMID: 18463241

Prosser LA, Ladapo JA, Rusinak D, Waisbren SL. Parental tolerance of false-positive newborn screening results.Arch Pediatr Adolesc Med. 2008 Sep;162(9):870-6.PMID: 18762606

Ladapo JA, Hoffmann U, Bamberg F, Nagurney JT, Cutler DM, Weinstein MC, Gazelle GS.Cost-effectiveness of coronary MDCT in the triage of patients with acute chest pain.AJR Am J Roentgenol. 2008 Aug;191(2):455-63.PMID: 18647917

Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008 Jul;1(2):84-94.PMID: 18633456

Maharaj AS, Walshe TE, Saint-Geniez M, Venkatesha S, Maldonado AE, Himes NC, Matharu KS, Karumanchi SA, D'Amore PA. VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma. J Exp Med. 2008 Feb 18;205(2):491-501. Epub 2008 Feb 11.

Bryan BA, Walshe TE, Mitchell DC, Havumaki JS, Saint-Geniez M, Maharaj AS, Maldonado AE, D'Amore PA. Coordinated vascular endothelial growth factor expression and signaling duringskeletal myogenic differentiation. Mol Biol Cell. 2008 Mar;19(3):994-1006. Epub 2007 Dec 19.

Saint-Geniez M, Maharaj AS, Walshe TE, Tucker BA, Sekiyama E, Kurihara T, Darland DC, Young MJ, D'Amore PA. Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors.PLoS ONE. 2008;3(11):e3554. Epub 2008 Nov 3.PMID: 18978936

Lin Y, Bloodgood BL, Hauser JL, Lapan AD, Koon AC, Kim TK, Hu LS, Malik AN, Greenberg ME. Activity-dependent regulation of inhibitory synapse development by Npas4.Nature. 2008 Oct 30;455(7217):1198-204. Epub 2008 Sep 24.PMID: 18815592

Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, Hannett N, Sharp PA, Bartel DP, Jaenisch R, Young RA. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 2008 Aug 8;134(3):521-33.

Marson A, Foreman R, Chevalier B, Bilodeau S, Kahn M, Young RA, Jaenisch R. Wnt signaling promotes reprogramming of somatic cells to pluripotency. Cell Stem Cell. 2008 Aug 7;3(2):132-5.

Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X, Hinkle G, Boehm JS, Beroukhim R, Weir BA, Mermel C, Barbie DA, Awad T, Zhou X, Nguyen T, Piqani B, Li C, Golub TR, Meyerson M, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE.Highly parallel identification of essential genes in cancer cells. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20380-5. Epub 2008 Dec 17. PMID: 19091943

Koivunen JP, Mermel C, Zejnullahu K, Murphy C, Lifshits E, Holmes AJ, Choi HG, Kim J, Chiang D, Thomas R, Lee J, Richards WG, Sugarbaker DJ, Ducko C, Lindeman N, Marcoux JP, Engelman JA, Gray NS, Lee C, Meyerson M, Jänne PA. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res. 2008 Jul 1;14(13):4275-83.PMID: 18594010

Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC. CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.Nature. 2008 Sep 25;455(7212):547-51. Epub 2008 Sep 14. PMID: 18794900

McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis GM, Olson JJ, Mikkelsen T, Lehman N, Aldape K, Yung WK, Bogler O, Weinstein JN, VandenBerg S, Berger M, Prados M, Muzny D, Morgan M, Scherer S, Sabo A, Nazareth L, Lewis L, Hall O, Zhu Y, Ren Y, Alvi O, Yao J, Hawes A, Jhangiani S, Fowler G, San Lucas A, Kovar C, Cree A, Dinh H, Santibanez J, Joshi V, Gonzalez-Garay ML, Miller CA, Milosavljevic A, Donehower L, Wheeler DA, Gibbs RA, Cibulskis K, Sougnez C, Fennell T, Mahan S, Wilkinson J, Ziaugra L, Onofrio R, Bloom T, Nicol R, Ardlie K, Baldwin J, Gabriel S, Lander ES, Ding L, Fulton RS, McLellan MD, Wallis J, Larson DE, Shi X, Abbott R, Fulton L, Chen K, Koboldt DC, Wendl MC, Meyer R, Tang Y, Lin L, Osborne JR, Dunford-Shore BH, Miner TL, Delehaunty K, Markovic C, Swift G, Courtney W, Pohl C, Abbott S, Hawkins A, Leong S, Haipek C, Schmidt H, Wiechert M, Vickery T, Scott S, Dooling DJ, Chinwalla A, Weinstock GM, Mardis ER, Wilson RK, Getz G, Winckler W, Verhaak RG, Lawrence MS, O'Kelly M, Robinson J, Alexe G, Beroukhim R, Carter S, Chiang D, Gould J, Gupta S, Korn J, Mermel C, Mesirov J, Monti S, Nguyen H, Parkin M, Reich M, Stransky N, Weir BA, Garraway L, Golub T, Meyerson M, Chin L, Protopopov A, Zhang J, Perna I, Aronson S, Sathiamoorthy N, Ren G, Yao J, Wiedemeyer WR, Kim H, Kong SW, Xiao Y, Kohane IS, Seidman J, Park P, Kucherlapati R, Laird PW, Cope L, Herman JG, Weisenberger DJ, Pan F, Van den Berg D, Van Neste L, Yi JM, Schuebel KE, Baylin SB, Absher DM, Li JZ, Southwick A, Brady S, Aggarwal A, Chung T, Sherlock G, Brooks JD, Myers RM, Spellman PT, Purdom E, Jakkula LR, Lapuk AV, Marr H, Dorton S, Choi YG, Han J, Ray A, Wang V, Durinck S, Robinson M, Wang NJ, Vranizan K, Peng V, Van Name E, Fontenay GV, Ngai J, Conboy JG, Parvin B, Feiler HS, Speed TP, Gray JW, Brennan C, Socci ND, Olshen A, Taylor BS, Lash A, Schultz N, Reva B, Antipin Y, Stukalov A, Gross B, Cerami E, Wang WQ, Qin LX, Seshan VE, Villafania L, Cavatore M, Borsu L, Viale A, Gerald W, Sander C, Ladanyi M, Perou CM, Hayes DN, Topal MD, Hoadley KA, Qi Y, Balu S, Shi Y, Wu J, Penny R, Bittner M, Shelton T, Lenkiewicz E, Morris S, Beasley D, Sanders S, Kahn A, Sfeir R, Chen J, Nassau D, Feng L, Hickey E, Barker A, Gerhard DS, Vockley J, Compton C, Vaught J, Fielding P, Ferguson ML, Schaefer C, Zhang J, Madhavan S, Buetow KH, Collins F, Good P, Guyer M, Ozenberger B, Peterson J, Thomson E. Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways.Nature. 2008 Oct 23;455(7216):1061-8. Epub 2008 Sep 4.PMID: 18772890

Sato-Jin K, Nishimura EK, Akasaka E, Huber W, Nakano H, Miller A, Du J, Wu M, Hanada K, Sawamura D, Fisher DE, Imokawa G. Epistatic connections between microphthalmia-associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders. FASEB J. 2008 Apr;22(4):1155-68. Epub 2007 Nov 26. PMID: 18039926

Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD. SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes. Neuron. 2008 Jan 24;57(2):232-247.

Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD. Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16;28(3):622-32.

Joshi PS, Molyneaux BJ, Feng L, Xie X, Macklis JD, Gan L. Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.Neuron. 2008 Oct 23;60(2):258-72.PMID: 18957218

Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 2008 May 1;22(9):1174-89.

Sendamarai AK, Ohgami RS, Fleming MD, Lawrence CM. Structure of the membrane proximal oxidoreductase domain of human Steap3, the dominant ferrireductase of the erythroid transferrin cycle. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7410-5. Epub 2008 May 21. PMID: 18495927

Philippakis AA, Qureshi AM, Berger MF, Bulyk ML. Design of Compact, Universal DNA Microarrays for Protein Binding Microarray Experiments. J Comput Biol. 2008 Jul 23. [Epub ahead of print]

Berger MF, Badis G, Gehrke AR, Talukder S, Philippakis AA, Peña-Castillo L, Alleyne TM, Mnaimneh S, Botvinnik OB, Chan ET, Khalid F, Zhang W, Newburger D, Jaeger SA, Morris QD, Bulyk ML, Hughes TR. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell. 2008 Jun 27;133(7):1266-76.

Warner JB, Philippakis AA, Jaeger SA, He FS, Lin J, Bulyk ML. Systematic identification of mammalian regulatory motifs' target genes and functions. Nat Methods. 2008 Apr;5(4):347-53. Epub 2008 Mar 2.

Warner JB, Philippakis AA, Jaeger SA, He FS, Lin J, Bulyk ML. Systematic identification of mammalian regulatory motifs' target genes and functions. Nat Methods. 2008 Mar 2 [Epub ahead of print] PMID: 18311145.

Ponce CR, Lomber SG, Born RT. Integrating motion and depth via parallel pathways. Nat Neurosci. 2008 Feb;11(2):216-23. Epub 2008 Jan 13.

Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol. 2008 Dec;19(12):2282-7. Epub 2008 Nov 5. PMID: 18987304

Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Exp Biol Med (Maywood). 2008 Feb;233(2):155-62.

Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression.Br J Cancer. 2008 Nov 4;99(9):1375-9. Epub 2008 Sep 16.PMID: 18797460

de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2008 Feb 15;22(4):449-62. Epub 2008 Feb 7.

Sarpeshkar R, Wattanapanitch W, Arfin SK, Rapoport BI, Mandal S, Baker MW, Fee MS, Musallam S, Andersen RA. Low-Power Circuits for Brain-Machine Interfaces. IEEE Transactions on Biomedical Circuits and Systems 2 (3): 173-183 (September 2008).

von Maltzahn G, Ren Y, Park JH, Min DH, Kotamraju VR, Jayakumar J, Fogal V, Sailor MJ, Ruoslahti E, Bhatia SN. In vivo tumor cell targeting with "click" nanoparticles.Bioconjug Chem. 2008 Aug;19(8):1570-8. Epub 2008 Jul 9.PMID: 18611045

De Jager PL, Rossin E, Pyne S, Tamayo P, Ottoboni L, Viglietta V, Weiner M, Soler D, Izmailova E, Faron-Yowe L, O'Brien C, Freeman S, Granados S, Parker A, Roubenoff R, Mesirov JP, Khoury SJ, Hafler DA, Weiner HL. Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells. Brain. 2008 Jul;131(Pt 7):1701-11. Epub 2008 Jun 21. PMID: 18567923

Rydzak CE, Goldie SJ. Cost-Effectiveness of Rapid Point-of-Care Prenatal Syphilis Screening in Sub-Saharan Africa. Sex Transm Dis. 2008 Jul 2. [Epub ahead of print]

Ryu J, Futai K, Feliu M, Weinberg R, Sheng M. Constitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction.J Neurosci. 2008 Aug 13;28(33):8178-88.PMID: 18701680

Hung AY, Futai K, Sala C, Valtschanoff JG, Ryu J, Woodworth MA, Kidd FL, Sung CC, Miyakawa T, Bear MF, Weinberg RJ, Sheng M. Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.J Neurosci. 2008 Feb 13;28(7):1697-708.PMID: 18272690

Safo P, Regehr WG. Timing dependence of the induction of cerebellar LTD. Neuropharmacology. 2008 Jan;54(1):213-8. Epub 2007 Jun 26. PMID: 17669443

Sankaran VG, Menne TF, Xu J, Akie TE, Lettre G, Van Handel B, Mikkola HK, Hirschhorn JN, Cantor AB, Orkin SH. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science. 2008 Dec 19;322(5909):1839-42. Epub 2008 Dec 4.PMID: 19056937 [PubMed - in process]

Sankaran VG, Orkin SH, Walkley CR. Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis.Genes Dev. 2008 Feb 15;22(4):463-475. Epub 2008 Feb 7. PMID: 18258751 [PubMed - as supplied by publisher]

Uda M, Galanello R, Sanna S, Lettre G, Sankaran VG, Chen W, Usala G, Busonero F, Maschio A, Albai G, Piras MG, Sestu N, Lai S, Dei M, Mulas A, Crisponi L, Naitza S, Asunis I, Deiana M, Nagaraja R, Perseu L, Satta S, Cipollina MD, Sollaino C, Moi P, Hirschhorn JN, Orkin SH, Abecasis GR, Schlessinger D, Cao A.Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1620-5. Epub 2008 Feb 1. PMID: 18245381 [PubMed - indexed for MEDLINE]

Walkley CR, Sankaran VG, Orkin SH. Rb and hematopoiesis: stem cells to anemia. Cell Div. 2008 Sep 8;3:13.PMID: 18775080

Lettre G, Sankaran VG, Bezerra MA, Araújo AS, Uda M, Sanna S, Cao A, Schlessinger D, Costa FF, Hirschhorn JN, Orkin SH. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11869-74. Epub 2008 Jul 30. PMID: 18667698

Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev. 2008 Jun 15;22(12):1662-76.

Seeburg DP, Sheng M.Activity-induced Polo-like kinase 2 is required for homeostatic plasticity of hippocampal neurons during epileptiform activity. J Neurosci. 2008 Jun 25;28(26):6583-91.

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Updated February 4, 2014

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