2002 - 2004

[A-L]      [M-Z]

Herz PR, Chen Y, Aguirre AD, Schneider K, Hsiung P, Fujimoto JG, Madden K, Schmitt J, Goodnow J, Petersen C. Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography. Opt Lett. 2004 Oct 1;29(19):2261-3.

Aguirre AJ, Bardeesy N, Sinha M, Lopez L, Tuveson DA, Horner J, Redston MS, DePinho RA. Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma. Genes Dev. 2003 Dec 15;17(24):3112-26. Epub 2003 Dec 17.

Aguirre AJ, Brennan C, Bailey G, Sinha R, Feng B, Leo C, Zhang Y, Zhang J, Gans JD, Bardeesy N, Cauwels C, Cordon-Cardo C, Redston MS, DePinho RA, Chin L. High-resolution characterization of the pancreatic adenocarcinoma genome. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9067-72.

Brennan C, Zhang Y, Leo C, Feng B, Cauwels C, Aguirre AJ, Kim M, Protopopov A, Chin L. High-resolution global profiling of genomic alterations with long oligonucleotide microarray. Cancer Res. 2004 Jul 15;64(14):4744-8

Sklar PA, Agyemang AF, Monastra R, Kress DR, Metcalf JA, Robinson MR, Masur H, Polis MA.. Five-year follow-up of a cohort of profoundly immunosuppressed patients discontinuing therapy for cytomegalovirus retinitis. AIDS. 2004 Feb 20;18(3):567-9.

Alenghat FJ, Ingber DE. Mechanotransduction: all signals point to cytoskeleton, matrix, and integrins. Sci STKE. 2002 Feb 12;2002(119):PE6. Review. 

Alenghat FJ, Nauli SM, Kolb R, Zhou J, Ingber DE. Global cytoskeletal control of mechanotransduction in kidney epithelial cells. Exp Cell Res. 2004 Nov 15;301(1):23-30

Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet. 2003 Feb;33(2):129-37.Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.               

Matthews BD, Overby DR, Alenghat FJ, Karavitis J, Numaguchi Y, Allen PG, Ingber DE.Mechanical properties of individual focal adhesions probed with a magnetic microneedle.Biochem Biophys Res Commun. 2004 Jan 16;313(3):758-64.

Ali MH, Peisach E, Allen KN, Imperiali B. X-ray structure analysis of a designed oligomeric miniprotein reveals a discrete quaternary architecture. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12183-8.

Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol. 2004 Jul 27;14(14):1296-302.

Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell. 2002 Jul 26;110(2):163-75.

Kim do H, Sarbassov dos D, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. GbetaL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR. Mol Cell 2003 Apr;11(4):895-904.

Steele LN, Balsara ZR, Starnbach MN. Hematopoietic cells are required to initiate a Chlamydia trachomatis-specific CD8+ T cell response. J Immunol. 2004 Nov 15;173(10):6327-37.

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM. Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science. 2003 Jun 20;300(5627):1921.

Begun J, McLeish MJ, Caine JM, Palant E, Grunewald GL, Martin JL. Crystallization of PNMT, the adrenaline-synthesizing enzyme, is critically dependent on a high protein concentration. Acta Crystallogr D Biol Crystallogr. 2002 Feb 1;58(Pt 2):314-5.

Sifri CD, Begun J, Ausubel FM, Calderwood SB. Caenorhabditis elegans as a Model Host for Staphylococcus aureus Pathogenesis. Infect Immun. 2003 Apr;71(4):2208-17.

Berry D , Lynn DM, Sasisekharan R, Langer R. Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death. Chem Biol. 2004 Apr;11(4):487-98.

Berry, D. The Legal and Economic Implications of Gene Patents. The Social Implications of the Human Genome Project.  Seguir, E. ed.  2002 Pgs. 2-10.

Berry D, Shriver Z, Venkataraman G, Sasisekahran R. Quantitative assessment of FGF regulation by cell surface heparan sulfates. Biochem Biophys Res Commun. 2004 Feb 20;314(4):994-1000.

Dull RO, Dinavahi R, Schwartz L, Humpharies DE, Berry D, Sasisekharan R, Garcia JGN. Lung endothelial heparan sulfates mediate cationic peptide-induced barrier dysfunction: a new role for the glycocalyx.  Am J Physiol Lung Cell Mol Physiol.  2003 Nov;285(5):L986-95.

Berry D, Shriver Z, Natke B, Kwan CP, Venkataraman G, Sasisekharan R. Heparan sulfate glycosaminoglycan derived from endothelial cells and smooth muscle cells differentially modulate Fibroblast Growth Factor-2 biological activity through Fibroblast Growth Factor Receptor-1. Biochem J. 2003 Jul 1;373(Pt 1):241-9.

Oancea E, Bezzerides VJ, Greka A, Clapham DE.  Mechanism of Persisten Protein Kinase D1 Translocation and Activation. Dev Cell. 2003 Apr;4(4):561-74.

Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE. Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol. 2004 Aug;6(8):709-20. Epub 2004 Jul 18.

Bezzerides VJ, Clapham, DE. Near-membrane protein dynamics revealed by evanescent field microscopy. Proc. SPIE. May 2004 Vol. 5467, p. 326-337.

Hopkins SR, Garg J, Bezzerides VJ, Balouch J, Levin DL. Pulmonary Blood Flow Heterogeneity during Hypoxia and High Altitude Pulmonary Edema. Am J Respir Crit Care Med. 2004 Oct 14 [Epub ahead of print]

Hopkins SR, Garg J, Bolar DS, Balouch J, Levin DL. Pulmonary Blood Flow Heterogeneity during Hypoxia and High Altitude Pulmonary Edema. Am J Respir Crit Care Med. 2004 Oct 14 [Epub ahead of print]

Glynn D*, Bortnick RA*, Morton AJ. Complexin II is essential for normal neurological function in mice. Hum Mol Genet. 2003 Oct 1;12(19):2431-48. Epub 2003 Jul 29.

Burke MD, Berger EM, Schreiber SL, Generating Diverse Skeletons of Small Molecules Combinatorially. Science. 2003 Oct 24;302(5645):613-18.

Burke MD, Schreiber SL. A Planning Strategy for Diversity-Oriented Synthesis. Angew Chem Int Ed Engl. 2004 Jan;43(1):46-58.

French MM, Rose S, Canseco J, Athanasiou KA. Chondrogenic differentiation of adult dermal fibroblasts.Ann Biomed Eng. 2004 Jan;32(1):50-6.PMID: 14964721.

Chae TH, Kim S, Marz KE, Hanson PI, Walsh CA.  The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004; Mar;36(3):264-70.

Chae TH, Kim S, Marz KE, Hanson PI, Walsh CA, The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004 Mar;36(3):264-70. Epub 2004 Feb 01.

Gray JM, Karow DS, Lu H, Chang AJ, Chang JS, Ellis RE, Marletta MA, Bargmann CI. Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature. 2004 Jul 15;430(6997):317-22. Epub 2004 Jun 27

Hazra A, Chang HH, and Nooijen M. First principles simulation of the UV absorption spectrum of ethylene using the vertical Franck-Condon approach. The Journal of Chemical Physics. August 1, 2004 (121), Issue 5, pp. 2125-2136.

Straight AF, Cheung A, Limouze J, Chen I, Westwood NJ, Sellers JR, Mitchison TJ. Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor. Science. 2003 Mar 14;299(5613):1743-7.

Chen IA, Szostak JW. Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles. Proc Natl Acad Sci U S A. 2004 May 25;101(21):7965-70. Epub 2004 May 17.

Chen IA, Szostak JW. A kinetic study of the growth of fatty acid vesicles. Biophys J. 2004 Aug; 87(2):988-98.

Chen IA, Roberts RW, Szostak JW. The emergence of competition between model protocells. Science. 2004 Sep 3;305(5689):1474-6.

Chyung JH, Selkoe DJ.  Inhibition of Receptor Mediated Endocytosis Demonstrates Generation of Amyloid b-Protein at the Cell Surface.  J Biol Chem. 2003 Dec 19;278(51):51035-43.

Lonze BE, Riccio A, Cohen S, Ginty DD. Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron. 2002 Apr 25;34(3):371-85.

Comander J*, Natarajan S*, Gimbrone MA Jr, Garcia-Cardena G. Improving the statistical detection of regulated genes from microarray data using intensity-based variance estimation. BMC Genomics. 2004 Feb 27;5(1):17.

Bradley PL, Myat MM, Comeaux CA., Andrew DJ.  Posterior migration of the salivary gland requires an intact visceral mesoderm and integrin function.  Developmental Biology. May 15 2003 257(2):249-262.        

Connor CW, Hynynen K. Patterns of thermal deposition in the skull during transcranial focused ultrasound surgery. IEEE Trans Biomed Eng. 2004 Oct;51(10):1693-706.

Rawat N, Connor CW, Jones JA, Kozlovskaya IB, Sullivan P. The correlation between aerobic fitness and motion sickness susceptibility. Aviat Space Environ Med. 2002 Mar;73(3):216-8.

Connor CW, Hynynen K. Bio-acoustic thermal lensing and nonlinear propagation in focused ultrasound surgery using large focal spots: a parametric study. Phys Med Biol. 2002 Jun 7;47(11):1911-28.

Connor CW, Clement GT, Hynynen K. A unified model for the speed of sound in cranial bone based on genetic algorithm optimization. Phys Med Biol. 2002 Nov 21;47(22):3925-44.

Beltran-Valero De Bernabe D, Currier S, Steinbrecher A, Celli J, Van Beusekom E, Van Der Zwaag B, Kayserili H, Merlini L, Chitayat D, Dobyns WB, Cormand B, Lehesjoki AE, Cruces J, Voit T, Walsh CA, Van Bokhoven H, Brunner HG. Mutations in the O-Mannosyltransferase Gene POMT1 Give Rise to the Severe Neuronal Migration Disorder Walker-Warburg Syndrome.Am J Hum Genet. 2002 Nov;71(5):1033-43.

Tran H, Brunet A, Grenier JM, Datta SR, Fornace AM, DiStefano PS, Chang LW and Greenberg ME.  The forkhead transcription factor FOXO3a/FKHRL1 induces a stress response by up-regulating GADD45. Science 2002 296:530-540.

Humbert S, Bryson EA, Cordelieres FP, Connors NC, Datta SR, Finkbeiner S, Greenberg ME and Saudou F. The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. Dev Cell. 2002 Jun;2(6):831-7.

Datta SR, Ranger A, Lin MZ, Sturgill JF, Ma Y, Dikkes P, Korsmeyer SJ and Greenberg ME.. Survival-factor mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis.
Dev Cell. 2002 Nov;3(5):631-43.

Ranger AM, Zha J, Harada H, Datta SR, Danial N, Gilmore AP, Kutok JL, Le Beau MM, Greenberg ME and Korsmeyer SJ. Bad-deficient mice develop diffuse large B cell lymphoma. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9324-9. Epub 2003 Jul 22.

Danial NN, Gramm CF, Scorrano L, Zhang C-Y, Krauss S, Ranger AM, Datta SR, Greenberg ME, Kickllder LJ, Lowell BB, Gygi SP and Korsmeyer SJ. BAD and glucokinase reside in a mitochondrial complex that integrates glycolosis and apoptosis. Nature. 2003 Aug 21;424(6951):952-6.

Webster SM, Del Camino D, Dekker JP, Yellen G. Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges. Nature. 2004 Apr 22;428(6985):864-8.

Dekker JP, Fodor A, Aldrich RW, Yellen G. A perturbation-based method for calculating explicit likelihood of evolutionary co-variance in multiple sequence alignments. Bioinformatics. 2004 Jul 10;20(10):1565-72.

Corbo JC, Deuel TA, Long JM, LaPorte P, Tsai E, Wynshaw-Boris A, Walsh CA. Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. J Neurosci. 2002 Sep 1;22(17):7548-57.

Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet. 2003 Feb;33(2):129-37.

Elia AE, Cantley LC, Yaffe MB.  Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science. 2003 Feb 21;299(5610):1228-31.

Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell. 2003 Oct 3;115(1):83-95.

Lowery DW, Mohammad DH, Elia AE, Yaffe MB.  The Polo-Box Domain: A Molecular Integrator of Mitotic Kinase Cascades and Polo-like Kinase Function. Cell Cycle. 2004 Mar-Apr;3(2):128-31.

Brown GE, Stewart MQ, Bissonnette SA, Elia AE, Wilker E, Yaffe MB. Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase. J Biol Chem. 2004 Jun 25;279(26):27059-68. Epub 2004 Apr 20

Igarashi J, Erwin PA, Dantas AP, Chen H, and Michel T, VEGF Induces S1P1 Receptors in Endothelial Cells: Implications for Cross-Talk Between Sphingolipid and Growth Factor Receptors. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10664-9.

Meneely PM, Farago AF, Kauffman TM. Crossover distribution and high interference for both the X chromosome and an autosome during oogenesis and spermatogenesis in Caenorhabditis elegans. Genetics 2002, 162(3): 1169-77.

Yao MW, Lin H, Schust DJ, Choe SE, Farago A, Ding Y, Michaud S, Church GM, Maas RL. Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus.  Molecular Endocrinology 2003, 17(4): 610-27.

Orange JS, Fassett MS, Koopman LA, Boyson JE, Strominger JL. Viral evasion of natural killer cells. Nat Immunol. 2002 Nov;3(11):1006-12.          

Munson AM, Haydon DH, Love SL, Fell GL, Palanivel VR, Rosenwald AG. Yeast ARL1 encodes a regulator of K+ influx. J Cell Sci. 2004 May 1;117(Pt 11):2309-20

Niebur GL, Feldstein MJ, Keaveny TM. Biaxial failure behavior of bovine tibial trabecular bone. J Biomech Eng. 2002 Dec;124(6):699-705. 

Hanna LA, Foreman RK, Tarasenko IA, Kessler DS, Labosky PA. Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 2002 Oct 15;16(20):2650-61.

Zhang X, Friedman A, Heaney S, Purcell P, Maas RL. Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis. Genes Dev. 2002 Aug 15;16(16):2097-107.

Humpherys D, Eggan K, Akutsu H, Friedman A, Hochedlinger K, Yanagimachi R, Lander ES, Golub TR, Jaenisch R. Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12889-94.

Friedman A, Perrimon N. Genome-wide high-throughput screens in functional genomics. Curr Opin Genet Dev. 2004 Oct;14(5):470-6.

Garibyan L, Lenahan C, Pories S. Metalloproteinases: Promising Tumor Markers for Breast Cancer Management. Review. Current Surgery. 2004 May-Jun;6:255-9.

Miller JH, Funchain P, Clendenin W, Huang T, Nguyen A, Wolff E, Yeung A, Chiang JH, Garibyan L, Slupska MM, Yang H. Escherichia coli Strains (ndk) Lacking Nucleoside Diphosphate Kinase Are Powerful Mutators for Base Substitutions and Frameshifts in Mismatch-Repair-Deficient Strains.Genetics. 2002 Sep;162(1):5-13.          

Garibyan L, Huang T, Kim M, Wolff E, Nguyen A, Nguyen T, Diep A, Hu K, Iverson A, Yang H, Miller JH. Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome. DNA Repair 2003 May;2(5):593-608.

Lenahan C, Garibyan L, Pories S.  The Role of Tumor Markers in Breast Cancer Management.  (2004).  Current Surgery. 2004 Nov-Dec;61;532-7.

Kim M, Wolf E, Huang T, Garibyan L, Earl AM, Battista JR, and Miller JH. Developing a Genetic System in Deinococcus radiodurans for Analyzing Mutations. Genetics. 2004 Feb;166:661-668.

Van Zante A, Gauguet J-M, Bistrup A, Tsay, D, von Andrian UH, Rosen SD. Lymphocyte-HEV Interactions in Lymph Nodes of a Sulfotransferase-deficient Mouse. J. Exp. Med. 2003 Nov 3;198(9):1289-300.

Gauguet JM, Rosen SD, Marth JD, Von Andrian UH. Core 2 branching {beta}1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B and T lymphocyte homing to peripheral lymph nodes. Blood. 2004 Aug 19 [Epub ahead of print]

LaVan DA, George PM, Langer R. Simple, three-dimensional microfabrication of electrodeposited structures. Angew Chem Int Ed Engl. 2003 Mar 17;42(11):1262-5.

Andricioaei I, Goel A, Herschbach D, Karplus M. Dependence of DNA polymerase replication rate on external forces: a model based on molecular dynamics simulations. Biophys J. 2004 Sep; 87(3):1478-97.

Goel A, Ellenberger T, Frank-Kamenetskii MD, Herschbach D. Unifying themes in DNA replication: reconciling single molecule kinetic studies with structural data on DNA polymerases. J Biomol Struct Dyn. 2002 Feb;19(4):571-84. 

Goel A, Astumian RD, Herschbach D. Tuning and switching a DNA polymerase motor with mechanical tension. Proc Natl Acad Sci U S A. 2003 Jul 17.                           

Goel A, Astumian RD, Herschbach D. Tuning and switching a DNA polymerase motor with mechanical tension. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9699-704.

Goel A, Herschbach D. Controlling the Speed and Direction of Molecular Motors that Replicate DNA in Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems, Bezrukov SM, Frauenfelder H, Moss F, Eds., Proc. of SPIE 5110 2003; pp. 63-68.

Grad YH, Roth FP, Halfon MS, Church GM. Prediction of similarly-acting cis-regulatory modules by subsequence profiling and comparative genomics in D. melanogaster and D. pseudoobscura. Bioinformatics. 2004 May 14

Halfon MS*, Grad Y*, Church GM, Michelson AM. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Genome Res. 2002 Jul;12(7):1019-28.*Equal contributors.                                        

Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J., Computational and experimental identification of C. elegans microRNAs. Mol Cell. 2003 May;11(5):1253-63.
Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G.  Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):360-5.

Greene JA. An ethnography of nonadherence: culture, poverty, and tuberculosis in urban Bolivia. Cult Med Psychiatry. 2004 Sep;28(3):401-25.

Greene, JA. Therapeutic Infidelities: Noncompliance Enters the Medical Literature: 1955-1975. Soc Hist Med 2004 17: 327-343

Greene JA. Attention to 'details': etiquette and the pharmaceutical salesman in postwar American. Soc Stud Sci. 2004 Apr;34(2):271-92.

Oancea E, Bezzerides VJ, Greka A, Clapham DE. Mechanism of Persisten Protein Kinase D1 Translocation and Activation. Dev Cell. 2003 Apr; 4(4):561-74.

Griffin EA Jr., Lowenstein, D. Pharmacology of the Ion Channel. In: Golan D, editor. Principles of Pharmacology. Boston (MA) Lippincott William and Wilkins, 2004. (book chapter)

Costigan M, Befort K, Karchewski L, Griffin RS, D'Urso D, Allchorne A, Sitarski J, Mannion JW, Pratt RE, Woolf CJ.Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci. 2002 Oct 25;3(1):16

Griffin RS, Mills CD, Costigan M, Woolf CJ.  Exploiting microarrays to reveal differential gene expression in the nervous system.  Genome Biol. 2003;4(2):105. Epub 2003 Jan 29.

Elsasser S, Chandler-Militello D, Muller B, Hanna J, Finley D. Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome. J Biol Chem. 2004 Jun 25;279(26):26817-22. Epub 2004 Apr 26.

Hanna J, Carroll K, Pfeffer SR. Identification of residues in TIP47 essential for Rab9 binding. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7450-4.

Leggett DS, Hanna J, Borodovsky A, Crosas B, Schmidt M, Baker RT, Walz T, Ploegh H, Finley D. Multiple associated proteins regulate proteasome structure and function. Mol Cell. 2002 Sep;10(3):495-507.               

Holliday LS, Welgus HG, Hanna J, Lee BS, Lu M, Jeffrey JJ, Gluck SL. Interstitial collagenase activity stimulates the formation of actin rings and ruffled membranes in mouse marrow osteoclasts. Calcif Tissue Int. 2003 Mar;72(3):206-14.

Hanna J, Leggett DS, Finley D. Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Mol Cell Biol. 2003 Dec;23(24):9251-61.

Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. Genomic analysis of mouse retinal development. PLoS Biol. 2004 Sep;2(9):E247. Epub 2004 Jun 29.

Harpavat S, Cepko CL. Thyroid hormone and retinal development: an emerging field. Thyroid. 2003 Nov;13(11):1013-9. Review.

Kasianowicz, JJ, SE Henrickson, M Misakian, HH Weetall, B Robertson and V Stanford. 2002. Physics of DNA threading through a nanometer pore and applications to simultaneous multianalyte sensing. NATO Advanced Research Workshop.  Structure and Dynamics of Confined Polymers. Kluwer Press. Eds. J.J. Kasianowicz, M. Kellermayer and D.W. Dreamer. pp. 141-163.

Rosenwald A, Wright G, Wiestner A, Chan WC, Connors JM, Campo E, Gascoyne RD, Grogan TM, Muller-Hermelink HK, Smeland EB, Chiorazzi M, Giltnane JM, Hurt EM, Zhao H, Averett L, Henrickson S, Yang L, Powell J, Wilson WH, Jaffe ES, Simon R, Klausner RD, Montserrat E, Bosch F, Greiner TC, Weisenburger DD, Sanger WG, Dave BJ, Lynch JC, Vose J, Armitage JO, Fisher RI, Miller TP, LeBlanc M, Ott G, Kvaloy S, Holte H, Delabie J, Staudt LM. The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell. 2003 Feb;3(2):185-97.   

Mempel TR, Henrickson SE, Von Andrian UH.  T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases.  Nature. 2004 Jan 8;427(6970):154-9.

Cahir-McFarland ED, Carter K, Rosenwald A, Giltnane JM, Henrickson SE, Staudt LM, Kieff E. Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells. J Virol. 2004 Apr;78(8):4108-19.

Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003 Jul;34(3):267-73.

Lovich MA, Creel C, Hong K, Hwang CW, Edelman ER. Carrier proteins determine local pharmacokinetics and arterial distribution of paclitaxel. J Pharm Sci. 2001 Sep;90(9):1324-35.

Hwang CW, Edelman ER. Arterial ultrastructure influences transport of locally delivered drugs. Circ Res. 2002 Apr 19;90(7):826-32.

Hwang CW
and Edelman ER. "Principles of continuum pharmacokinetics in stent-based drug elution," in Handbook of Drug Eluting Stents. PW Serruys and Gershlick A, Eds. Martin Dunitz Ltd. 2002.              

Hwang CW, Wu D, Edelman ER. Impact of drug properties and transport on the local pharmacology of drug-eluting stents. Int J Cardiovasc Intervent. 2003. 5(1): 7-12.

Janicki C, Hwang CW, Edelman ER. Dose model for stent-based delivery of a radioactive compound for the treatment of restenosis in coronary arteries. Med Phys. 2003 Oct;30(10):2622-8.

Iweala OI. HIV diagnostic tests: an overview. Contraception. 2004 Aug;70(2):141-7.

Jung, D., Bassing, C.H., Fugmann, S.D., Cheng, H-L., Schatz, D.G., and Alt, F.W.  Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted V(D)J recombination in nonlymphoid cells.  Immunity. 2003 Jan;18(1):65-74.

Wu, C., Bassing, C.H., Jung, D., Woodman, B.B., Foy, D., and Alt, F.W.  Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence.  Immunity 2003  18, 75-85.                               

Jung D, Bassing CH, Fugmann SD, Cheng HL, Schatz DG, Alt FW.  Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted V(D)J recombination in nonlymphoid cells. Immunity.  2003 Jan;18(1):65-74.

Wu C, Bassing CH, Jung D, Woodman BB, Foy D, Alt FW.  Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence. Immunity. 2003 Jan;18(1):75-85.

Jung D, Alt FW. Unraveling V(D)J recombination: insights into gene regulation. Cell. 2004 Jan 23;116(2):299-311.               

Katz SG, Cantor AB, Orkin SH. Interaction between FOG-1 and the Corepressor C-Terminal Binding Protein Is Dispensable for Normal Erythropoiesis In Vivo. Mol Cell Biol. 2002 May;22(9):3121-8.               

Esler WP, Kimberly WT, Ostaszewski BL, Ye W, Diehl TS, Selkoe DJ, Wolfe MS. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2720-2725.

Esler WP, Das C, Campbell WA, Kimberly WT, Kornilova AY, Diehl TS, Ye W, Ostaszewski BL, Xia W, Selkoe DJ, Wolfe MS. Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase. Nat Cell Biol. 2002 May;4(5):E110-1; discussion E111-2.

Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Complex N-linked Glycosylated Nicastrin Associates with Active gamma -Secretase and Undergoes Tight Cellular Regulation. J Biol Chem. 2002 Sep 20;277(38):35113-7.            

Kimberly WT, Esler WP, Ye W, Ostaszewski BL, Gao J, Diehl TS, Selkoe DJ and Wolfe MS.  Notch and amyloid precursor protein are cleaved by similar gamma-secretase(s).  Biochemistry, 42: 137-144 (2003).

Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS and Selkoe DJ.  gamma-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1 and pen-2.  Proc. Natl. Acad. Sci. U.S.A., 100: 6382-6387 (2003).                               

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* these authors contributed equally to this work

Updated 01/21/2010