Publications

2018

 

Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A,  Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I,  Gehrke L, Zhang F, Sabeti PC. Field-deployable viral diagnostics using CRISPR-Cas13. Science. 2018 Apr 27;360(6387):444-448. doi: 10.1126/science.aas8836. PubMed PMID: 29700266.

 

Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F. Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6. Science. 2018 Apr 27;360(6387):439-444. doi: 10.1126/science.aaq0179. Epub  2018 Feb 15. PubMed PMID: 29449508; PubMed Central PMCID: PMC5961727.

 

Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H,

Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science. 2018 Sep

21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. PubMed PMID: 30166441

 

Sharma A, Toepfer CN, Ward T, Wasson L, Agarwal R, Conner DA, Hu JH, Seidman CE. CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells. Curr Protoc Hum Genet. 2018 Jan 24;96:21.11.1-21.11.20. doi: 10.1002/cphg.52. PubMed PMID: 29364519; PubMed Central PMCID: PMC5785097.

 

Berne C, Ellison CK, Agarwal R, Severin GB, Fiebig A, Morton RI 3rd, Waters CM, Brun YV. Feedback regulation of Caulobacter crescentus holdfast synthesis by

flagellum assembly via the holdfast inhibitor HfiA. Mol Microbiol. 2018 Oct;110(2):219-238. doi: 10.1111/mmi.14099. Epub 2018 Oct 5. PubMed PMID: 30079982; PubMed Central PMCID: PMC6195837.

 

Cai T, Zhang Y, Ho YL, Link N, Sun J, Huang J, Cai TA, Damrauer S, Ahuja Y, Honerlaw J, Huang J, Costa L, Schubert P, Hong C, Gagnon D, Sun YV, Gaziano JM,

Wilson P, Cho K, Tsao P, O'Donnell CJ, Liao KP; VA Million Veteran Program. Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects

of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study. JAMA Cardiol. 2018 Sep 1;3(9):849-857. doi: 10.1001/jamacardio.2018.2287. PubMed

PMID: 30090940.

 

Short FL, Akusobi C, Broadhurst WR, Salmond GPC. The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity. Sci Rep. 2018 Jan 17;8(1):1013. doi: 10.1038/s41598-017-18696-x. PubMed PMID: 29343718; PubMed Central PMCID: PMC5772629.

 

Allsop SA, Wichmann R, Mills F, Burgos-Robles A, Chang CJ, Felix-Ortiz AC, Vienne A, Beyeler A, Izadmehr EM, Glober G, Cum MI, Stergiadou J, Anandalingam KK, Farris K, Namburi P, Leppla CA, Weddington JC, Nieh EH, Smith AC, Ba D, Brown EN, Tye KM. Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. Cell. 2018 May 31;173(6):1329-1342.e18. doi: 10.1016/j.cell.2018.04.004. Epub 2018 May 3. PubMed PMID: 29731170.

 

Zhang Y, Malem-Shinitski N, Allsop SA, M Tye K, Ba D. Estimating a Separably Markov Random Field from Binary Observations. Neural Comput. 2018 Apr;30(4):1046-1079. doi: 10.1162/neco_a_01059. Epub 2018 Jan 30. PubMed PMID: 29381446.

 

Matthew Basilico, Abhiram Bhashyam, Emma Harrington, Marilyn Heng. Initial Opioid Supply Influences Long-Term Use and Doctor Shopping: An Instrumental Variables Approach, American College of Surgeons Clinical Congress. Boston, MA October 2018. Winner: Excellence in Research Award (Health Policy).

 

Matthew Basilico, Abhiram Bhashyam, Marilyn Heng. Racial bias in initial opioid prescribing for orthopaedic trauma patients. Boston, MA October 2018.

 

Abhiram Bhashyam, Matthew Basilico, Michael Weaver, Mitchel Harris, Marilyn Heng. An analysis of initial post-operative opioid prescribing patterns in orthopaedic trauma and a technique to determine prescribing guidelines. American Academy of Orthopaedic Surgeons Annual Meeting. 2018

 

Matthew Basilico, Abhiram R. Bhashyam, Mitchel Harris, Marilyn Heng. Prescription opioid type is not associated with increased risk of long-term use in opiate naïve patients after orthopaedic surgery. Accepted ASSH 2018.

 

Baum, M. L., Savulescu, J., Singh, I. in press. Chapter 5: A New Ethics For 21st Century Psychiatry. In: Geddes, J., Andreasen, N., and Goodwin, G. (eds). New Oxford Textbook of Psychiatry (3rd edition).

 

Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA. Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor

Ufd1-Npl4. Nat Struct Mol Biol. 2018 Jul;25(7):616-622. doi: 10.1038/s41594-018-0085-x. Epub 2018 Jul 2. PubMed PMID: 29967539; PubMed Central PMCID: PMC6044470.

 

Schmalzer, Sigrid, Daniel S. Chard, and Alyssa Botelho, eds. Science for the People: Documents from America's Movement of Radical Scientists, 1969-1989. Amherst, MA: University of Massachusetts Press, 2018.

 

Botelho, Alyssa. "Biology and Medicine." In Science for the People: Documents from America's Movement of Radical Scientists, 1969-1989, edited by Sigrid Schmalzer, Daniel S. Chard, and Alyssa Botelho. Amherst, MA: University of Massachusetts Press, 2018.

 

Botelho, Alyssa. "Race and Gender." In Science for the People: Documents from America's Movement of Radical Scientists, 1969-1989, edited by Sigrid Schmalzer, Daniel S. Chard, and Alyssa Botelho. Amherst, MA: University of Massachusetts Press, 2018.

 

Moise G, Morales Y, Beaumont V, Caradonna T, Loria JP, Johnson SJ, Hengge AC.  A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the

Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases. Biochemistry. 2018 Sep 11;57(36):5315-5326. doi: 10.1021/acs.biochem.8b00663. Epub 2018 Aug 28. PubMed PMID: 30110154.

 

Pan J, Meyers RM, Michel BC, Mashtalir N, Sizemore AE, Wells JN, Cassel SH, Vazquez F, Weir BA, Hahn WC, Marsh JA, Tsherniak A, Kadoch C. Interrogation of

Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale  Fitness Screens. Cell Syst. 2018 May 23;6(5):555-568.e7. doi:

10.1016/j.cels.2018.04.011. Epub 2018 May 16. PubMed PMID: 29778836.

 

Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch

C. Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes. Cell. 2018 Oct 18. pii: S0092-8674(18)31244-3. doi:

10.1016/j.cell.2018.09.032. [Epub ahead of print] PubMed PMID: 30343899.

 

Brown JM, Campbell JP, Beers A, Chang K, Ostmo S, Chan RVP, Dy J, Erdogmus D, Ioannidis S, Kalpathy-Cramer J, Chiang MF; Imaging and Informatics in Retinopathy of Prematurity (i-ROP) Research Consortium. Automated Diagnosis of Plus Disease in Retinopathy of Prematurity Using Deep Convolutional Neural Networks. JAMA Ophthalmol. 2018 May 2. doi: 10.1001/jamaophthalmol.2018.1934. [Epub ahead of print] PubMed PMID: 29801159.

 

Chang K, Balachandar N, Lam C, Yi D, Brown J, Beers A, Rosen B, Rubin DL, Kalpathy-Cramer J. Distributed deep learning networks among institutions for

medical imaging. J Am Med Inform Assoc. 2018 Mar 29. doi: 10.1093/jamia/ocy017. [Epub ahead of print] PubMed PMID: 29617797.

 

Tang L, Deng L, Bai HX, Sun J, Neale N, Wu J, Wang Y, Chang K, Huang RY, Zhang PJ, Li X, Xiao B, Cao Y, Tao Y, Yang L. Reduced expression of DNA repair genes and chemosensitivity in 1p19q codeleted lower-grade gliomas. J Neurooncol. 2018 Jun 19. doi: 10.1007/s11060-018-2915-4. [Epub ahead of print] PubMed PMID: 29923053

 

Winzeck S, Hakim A, McKinley R, Pinto JAADSR, Alves V, Silva C, Pisov M, Krivov E, Belyaev M, Monteiro M, Oliveira A, Choi Y, Paik MC, Kwon Y, Lee H, Kim

BJ, Won JH, Islam M, Ren H, Robben D, Suetens P, Gong E, Niu Y, Xu J, Pauly JM, Lucas C, Heinrich MP, Rivera LC, Castillo LS, Daza LA, Beers AL, Arbelaezs P,

Maier O, Chang K, Brown JM, Kalpathy-Cramer J, Zaharchuk G, Wiest R, Reyes M. ISLES 2016 and 2017-Benchmarking Ischemic Stroke Lesion Outcome Prediction Based on Multispectral MRI. Front Neurol. 2018 Sep 13;9:679. doi: 10.3389/fneur.2018.00679. eCollection 2018. PubMed PMID: 30271370; PubMed Central PMCID: PMC6146088.

 

Tyssowski KM, DeStefino NR, Cho JH, Dunn CJ, Poston RG, Carty CE, Jones RD, Chang SM, Romeo P, Wurzelmann MK, Ward JM, Andermann ML, Saha RN, Dudek SM, Gray  JM. Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron. 2018 May 2;98(3):530-546.e11. doi:

10.1016/j.neuron.2018.04.001. Epub 2018 Apr 19. PubMed PMID: 29681534; PubMed Central PMCID: PMC5934296.

 

Lima Queiroz A, Zhang B, Comstock DE, Hao Y, Eriksson M, Hydbring P, Vakifahmetoglu-Norberg H, Norberg E. miR-126-5p targets Malate Dehydrogenase 1 in non-small cell lung carcinomas. Biochem Biophys Res Commun. 2018 May 5;499(2):314-320. doi: 10.1016/j.bbrc.2018.03.154. Epub 2018 Mar 26. PubMed PMID: 29574159.

 

DiRisio AC, Muskens IS, Cote DJ, Babu M, Gormley WB, Smith TR, Moojen WA, Broekman ML. Oversight and Ethical Regulation of Conflicts of Interest in

Neurosurgery in the United States. Neurosurgery. 2018 May 30. doi: 10.1093/neuros/nyy227. [Epub ahead of print] PubMed PMID: 29850841.

 

Zaidi HA, Penn DL, Cote DJ, Laws ER Jr. Root cause analysis of diagnostic and  surgical failures in the treatment of suspected Cushing's disease. J Clin

Neurosci. 2018 Jul;53:153-159. doi: 10.1016/j.jocn.2018.04.055. Epub 2018 Apr 30. PubMed PMID: 29716804.

 

Martin E, Muskens IS, Senders JT, Cote DJ, Smith TR, Broekman MLD. A nationwide analysis of 30-day adverse events, unplanned readmission, and length

of hospital stay after peripheral nerve surgery in extremities and the brachial plexus. Microsurgery. 2018 Apr 15. doi: 10.1002/micr.30330. [Epub ahead of print]

PubMed PMID: 29656387.

 

Zaki MM, Cote DJ, Muskens IS, Smith TR, Broekman ML. Defining Innovation in Neurosurgery: Results from an International Survey. World Neurosurg. 2018

Jun;114:e1038-e1048. doi: 10.1016/j.wneu.2018.03.142. Epub 2018 Mar 29. PubMed PMID: 29604357.

 

Alotaibi NM, Noormohamed N, Cote DJ, Alharthi S, Doucette J, Zaidi HA, Mekary  RA, Smith TR. Physiologic Growth Hormone-Replacement Therapy and

Craniopharyngioma Recurrence in Pediatric Patients: A Meta-Analysis. World Neurosurg. 2018 Jan;109:487-496.e1. doi: 10.1016/j.wneu.2017.09.164. Epub 2017 Oct 4. Review. PubMed PMID: 28987837; PubMed Central PMCID: PMC5729106.

 

Senders JT, Goldhaber NH, Cote DJ, Muskens IS, Dawood HY, De Vos FYFL, Gormley WB, Smith TR, Broekman MLD. Venous thromboembolism and intracranial hemorrhage after craniotomy for primary malignant brain tumors: a National Surgical Quality  Improvement Program analysis. J Neurooncol. 2018 Jan;136(1):135-145. doi: 10.1007/s11060-017-2631-5. Epub 2017 Oct 16. PubMed PMID: 29039075; PubMed Central PMCID: PMC5754452.

 

Burke WT, Cote DJ, Iuliano SI, Zaidi HA, Laws ER. A practical method for prevention of readmission for symptomatic hyponatremia following transsphenoidal

surgery. Pituitary. 2018 Feb;21(1):25-31. doi: 10.1007/s11102-017-0843-5. PubMed  PMID: 29075986.

 

Almutairi RD, Muskens IS, Cote DJ, Dijkman MD, Kavouridis VK, Crocker E, Ghazawi K, Broekman MLD, Smith TR, Mekary RA, Zaidi HA. Gross total resection of  pituitary adenomas after endoscopic vs. microscopic transsphenoidal surgery: a meta-analysis. Acta Neurochir (Wien). 2018 Jan 6. doi: 10.1007/s00701-017-3438-z. [Epub ahead of print] Review. PubMed PMID: 29307020.

 

Altuwaijri N, Cote DJ, Lamba N, Albenayan W, Ren SP, Zaghloul I, Doucette J, Zaidi HA, Mekary RA, Smith TR. Headache Resolution After Rathke Cleft Cyst

Resection: A Meta-Analysis. World Neurosurg. 2018 Jan 5. pii: S1878-8750(18)30025-1. doi: 10.1016/j.wneu.2017.12.170. [Epub ahead of print]

PubMed PMID: 29309984.

 

Alreshidi M, Cote DJ, Dasenbrock HH, Acosta M, Can A, Doucette J, Simjian T, Hulou MM, Wheeler LA, Huang K, Zaidi HA, Du R, Aziz-Sultan MA, Mekary RA, Smith TR. Coiling Versus Microsurgical Clipping in the Treatment of Unruptured Middle Cerebral Artery Aneurysms: A Meta-Analysis. Neurosurgery. 2018 Feb 9. doi:

10.1093/neuros/nyx623. [Epub ahead of print] PubMed PMID: 29438551.

 

Senders JT, Muskens IS, Cote DJ, Goldhaber NH, Dawood HY, Gormley WB, Broekman MLD, Smith TR. Thirty-Day Outcomes After Craniotomy for Primary Malignant Brain Tumors: A National Surgical Quality Improvement Program Analysis. Neurosurgery. 2018 Feb 22. doi: 10.1093/neuros/nyy001. [Epub ahead of print] PubMed PMID: 29481613.

 

Ostrom Q*, Cote DJ*, Ascha M, Kruchko C, Barnholtz-Sloan JS. "Patterns of adult glioma incidence and survival by race and ethnicity in the United States from 2000-2014." JAMA Oncology. 2018 Jun; [epub ahead of print]. PMID: 29931168; PubMed Central PMCID: PMC6143018.

 

Cote DJ, Downer MK, Smith TR, Smith-Warner SA, Egan KM, Stampfer MJ. Height, waist circumference, body mass index, and body somatotype across the life course  and risk of glioma. Cancer Causes Control. 2018 Aug;29(8):707-719. doi: 10.1007/s10552-018-1052-x. Epub 2018 Jun 26. PubMed PMID: 29943102.

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Tyssowski KM, DeStefino NR, Cho JH, Dunn CJ, Poston RG, Carty CE, Jones RD, Chang SM, Romeo P, Wurzelmann MK, Ward JM, Andermann ML, Saha RN, Dudek SM, Gray  JM. Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron. 2018 May 2;98(3):530-546.e11. doi: 10.1016/j.neuron.2018.04.001. Epub 2018 Apr 19. PubMed PMID: 29681534; PubMed Central PMCID: PMC5934296.

 

Fan X, Xie B, Zou J, Luo J, Qin Z, D'Gama AM, Shi J, Yi S, Yang Q, Wang J, Luo S, Chen S, Agrawal PB, Li Q, Shen Y. Novel ETFDH mutations in four cases of
riboflavin responsive multiple acyl-CoA dehydrogenase deficiency. Mol Genet Metab Rep. 2018 Jun 11;16:15-19. doi: 10.1016/j.ymgmr.2018.05.007. eCollection 2018 Sep. PubMed PMID: 29988809; PubMed Central PMCID: PMC6031868.

 

Fan X, Xie B, Zou J, Luo J, Qin Z, D'Gama AM, Shi J, Yi S, Yang Q, Wang J, Luo S, Chen S, Agrawal PB, Li Q, Shen Y. Novel ETFDH mutations in four cases of

riboflavin responsive multiple acyl-CoA dehydrogenase deficiency. Mol Genet Metab Rep. 2018 Jun 11;16:15-19. doi: 10.1016/j.ymgmr.2018.05.007. eCollection 2018 Sep. PubMed PMID: 29988809; PubMed Central PMCID: PMC6031868.

 

Ching T, Himmelstein DS, Beaulieu-Jones BK, Kalinin AA, Do BT, Way GP, Ferrero E, Agapow PM, Zietz M, Hoffman MM, Xie W, Rosen GL, Lengerich BJ, Israeli J,

Lanchantin J, Woloszynek S, Carpenter AE, Shrikumar A, Xu J, Cofer EM, Lavender CA, Turaga SC, Alexandari AM, Lu Z, Harris DJ, DeCaprio D, Qi Y, Kundaje A, Peng  Y, Wiley LK, Segler MHS, Boca SM, Swamidass SJ, Huang A, Gitter A, Greene CS. Opportunities and obstacles for deep learning in biology and medicine. J R Soc Interface. 2018 Apr;15(141). pii: 20170387. doi: 10.1098/rsif.2017.0387. Review.  PubMed PMID: 29618526; PubMed Central PMCID: PMC5938574.

 

Wutz A, Loonis R, Roy JE, Donoghue JA, Miller EK. Different Levels of Category Abstraction by Different Dynamics in Different Prefrontal Areas. Neuron. 2018 Feb

7;97(3):716-726.e8. doi: 10.1016/j.neuron.2018.01.009. Epub 2018 Jan 27. PubMed PMID: 29395915.

  

Dosumu-Johnson RT, Cocoran AE, Chang Y, Nattie E, Dymecki SM. Acute perturbation of Pet1-neuron activity in neonatal mice impairs cardiorespiratory

homeostatic recovery. Elife. 2018 Oct 23;7. pii: e37857. doi: 10.7554/eLife.37857. PubMed PMID: 30350781.

 

Drosu NC, Edelman ER, Housman DE. Could antiretrovirals be treating EBV in MS? A case report. Mult Scler Relat Disord. 2018 May;22:19-21. doi: 10.1016/j.msard.2018.02.029. Epub 2018 Feb 27. PubMed PMID: 29510325.

 

Wolfe JM, Fadzen CM, Choo ZN, Holden RL, Yao M, Hanson GJ, Pentelute BL. Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery. ACS Cent Sci. 2018 Apr 25;4(4):512-520. doi: 10.1021/acscentsci.8b00098. Epub 2018 Apr 5. PubMed PMID: 29721534; PubMed Central PMCID: PMC5920612.

 

Wolfe JM, Fadzen CM, Holden RL, Yao M, Hanson GJ, Pentelute BL. Perfluoroaryl  Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides.

Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4756-4759. doi: 10.1002/anie.201801167. Epub 2018 Mar 14. PubMed PMID: 29479836.

 

Donovan KA, An J, Nowak RP, Yuan JC, Fink EC, Berry BC, Ebert BL, Fischer ES.  Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. Elife. 2018 Aug 1;7. pii: e38430. doi: 10.7554/eLife.38430. PubMed PMID: 30067223; PubMed Central PMCID: PMC6156078.

 

Fink EC, McConkey M, Adams DN, Haldar SD, Kennedy JA, Guirguis AA, Udeshi ND,  Mani DR, Chen M, Liddicoat B, Svinkina T, Nguyen AT, Carr SA, Ebert BL. Crbn (I391V) is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice. Blood. 2018 Oct 4;132(14):1535-1544. doi: 10.1182/blood-2018-05-852798. Epub 2018 Jul 31. PubMed PMID: 30064974; PubMed Central PMCID: PMC6172563.

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC. An alternative splicing switch in FLNB  promotes the mesenchymal cell state in human breast cancer. Elife. 2018 Jul 30;7. pii: e37184. doi: 10.7554/eLife.37184. PubMed PMID: 30059005; PubMed Central PMCID: PMC6103745.

 

Anahtar MN, Gootenberg DB, Mitchell CM, Kwon DS. Cervicovaginal Microbiota and Reproductive Health: The Virtue of Simplicity. Cell Host Microbe. 2018 Feb 14;23(2):159-168. doi: 10.1016/j.chom.2018.01.013. Review. PubMed PMID: 29447695

 

Grossman SR, Engreitz J, Ray JP, Nguyen TH, Hacohen N, Lander ES. Positional specificity of different transcription factor classes within enhancers. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7222-E7230. doi: 10.1073/pnas.1804663115. Epub 2018 Jul 9. PMID: 29987030

 

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S,  Palamara PF, Pinello L, Patterson N, Adams RP, Price AL. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk. Nat Genet. 2018 Oct;50(10):1483-1493. doi: 10.1038/s41588-018-0196-7. Epub 2018 Sep 3. PubMed PMID: 30177862; PubMed Central PMCID: PMC6202062.

 

Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J, Howard TP, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B,  Steelman S, Vazquez F, Tsherniak A, Aguirre AJ, Doench JG, Piccioni F, Roberts CWM, Meyerson M, Getz G, Johannessen CM, Root DE, Hahn WC. Mutational processes shape the landscape of TP53 mutations in human cancer. Nat Genet. 2018 Oct;50(10):1381-1387. doi: 10.1038/s41588-018-0204-y. Epub 2018 Sep 17. PubMed PMID: 30224644; PubMed Central PMCID: PMC6168352.

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M, Deb C, Wadsworth MH 2nd, Hughes TK, Kazer SW, Yoshimoto E, Cahill KN, Bhattacharyya N, Katz HR, Berger B, Laidlaw TM, Boyce JA, Barrett NA, Shalek AK. Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature. 2018 Aug;560(7720):649-654. doi: 10.1038/s41586-018-0449-8. Epub 2018 Aug 22. PubMed PMID: 30135581; PubMed Central PMCID: PMC6133715.

 

Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH 2nd, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol. 2018 Jun 5;16(1):62. doi: 10.1186/s12915-018-0527-2. PubMed PMID: 29871632; PubMed Central PMCID: PMC5989470.

 

Silver JN, Ashbaugh CD, Miles JJ, Wu H, Marecki GT, Hwang JK, Jiao JA, Abrams  M, Sullivan EJ, Wesemann DR. Deployment of Transchromosomal Bovine for Personalized Antimicrobial Therapy. Clin Infect Dis. 2018 Mar 19;66(7):1116-1119. doi: 10.1093/cid/cix977. PubMed PMID: 29272362.

 

Kalinich M, Haber DA. Cancer detection: Seeking signals in blood. Science. 2018 Feb 23;359(6378):866-867. doi: 10.1126/science.aas9102. PubMed PMID: 29472467.

 

Kwan TT, Bardia A, Spring LM, Giobbie-Hurder A, Kalinich M, Dubash T, Sundaresan T, Hong X, LiCausi JA, Ho U, Silva EJ, Wittner BS, Sequist LV, Kapur

R, Miyamoto DT, Toner M, Haber DA, Maheswaran S. A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and

Metastatic Breast Cancer. Cancer Discov. 2018 Oct;8(10):1286-1299. doi: 10.1158/2159-8290.CD-18-0432. Epub 2018 Aug 13. PubMed PMID: 30104333; PubMed Central PMCID: PMC6170694.

 

Hong X, Sullivan RJ, Kalinich M, Kwan TT, Giobbie-Hurder A, Pan S, LiCausi JA, Milner JD, Nieman LT, Wittner BS, Ho U, Chen T, Kapur R, Lawrence DP, Flaherty KT, Sequist LV, Ramaswamy S, Miyamoto DT, Lawrence M, Toner M, Isselbacher KJ, Maheswaran S, Haber DA. Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2467-2472. doi: 10.1073/pnas.1719264115. Epub 2018 Feb 16. PubMed PMID: 29453278; PubMed Central PMCID: PMC5877960.

 

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting  DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA. An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer. Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4. PubMed PMID: 29301747.

 

Bhan I, Mosesso K, Goyal L, Philipp J, Kalinich M, Franses JW, Choz M, Oklu R, Toner M, Maheswaran S, Haber DA, Zhu AX, Chung RT, Aryee M, Ting DT. Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease. Gastroenterology. 2018 Dec;155(6):2016-2018.e11. doi: 10.1053/j.gastro.2018.09.020. Epub 2018 Sep 13. PubMed PMID: 30218669.

 

Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala  NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M. Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing. Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18. PubMed PMID: 29909985; PubMed Central PMCID: PMC6046279.

 

Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linnér R, Fontana MA, Kundu T, Lee C, Li H, Li R, Royer  R, Timshel PN, Walters RK, Willoughby EA, Yengo L; 23andMe Research Team; COGENT  (Cognitive Genomics Consortium); Social Science Genetic Association Consortium, Alver M, Bao Y, Clark DW, Day FR, Furlotte NA, Joshi PK, Kemper KE, Kleinman A, Langenberg C, Mägi R, Trampush JW, Verma SS, Wu Y, Lam M, Zhao JH, Zheng Z, Boardman JD, Campbell H, Freese J, Harris KM, Hayward C, Herd P, Kumari M, Lencz  T, Luan J, Malhotra AK, Metspalu A, Milani L, Ong KK, Perry JRB, Porteous DJ, Ritchie MD, Smart MC, Smith BH, Tung JY, Wareham NJ, Wilson JF, Beauchamp JP, Conley DC, Esko T, Lehrer SF, Magnusson PKE, Oskarsson S, Pers TH, Robinson MR, Thom K, Watson C, Chabris CF, Meyer MN, Laibson DI, Yang J, Johannesson M, Koellinger PD, Turley P, Visscher PM, Benjamin DJ, Cesarini D. Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nat Genet. 2018 Aug;50(8):1112-1121. doi:  10.1038/s41588-018-0147-3. Epub 2018 Jul 23. PubMed PMID: 30038396.

 

Siddle KJ, Eromon P, Barnes KG, Mehta S, Oguzie JU, Odia I, Schaffner SF, Winnicki SM, Shah RR, Qu J, Wohl S, Brehio P, Iruolagbe C, Aiyepada J, Uyigue E,  Akhilomen P, Okonofua G, Ye S, Kayode T, Ajogbasile F, Uwanibe J, Gaye A, Momoh M, Chak B, Kotliar D, Carter A, Gladden-Young A, Freije CA, Omoregie O, Osiemi B, Muoebonam EB, Airende M, Enigbe R, Ebo B, Nosamiefan I, Oluniyi P, Nekoui M, Ogbaini-Emovon E, Garry RF, Andersen KG, Park DJ, Yozwiak NL, Akpede G, Ihekweazu C, Tomori O, Okogbenin S, Folarin OA, Okokhere PO, MacInnis BL, Sabeti PC, Happi  CT. Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018. N Engl J Med. 2018 Nov 1;379(18):1745-1753. doi: 10.1056/NEJMoa1804498. Epub 2018 Oct 17. PubMed PMID: 30332564; PubMed Central PMCID: PMC6181183.

 

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S,

Palamara PF, Pinello L, Patterson N, Adams RP, Price AL. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.

Nat Genet. 2018 Oct;50(10):1483-1493. doi: 10.1038/s41588-018-0196-7. Epub 2018 Sep 3. PubMed PMID: 30177862; PubMed Central PMCID: PMC6202062.

 

Sakabe S, Sullivan BM, Hartnett JN, Robles-Sikisaka R, Gangavarapu K, Cubitt B, Ware BC, Kotliar D, Branco LM, Goba A, Momoh M, Sandi JD, Kanneh L, Grant DS,  Garry RF, Andersen KG, de la Torre JC, Sabeti PC, Schieffelin JS, Oldstone MBA. Analysis of CD8(+) T cell response during the 2013-2016 Ebola epidemic in West Africa. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7578-E7586. doi: 10.1073/pnas.1806200115. Epub 2018 Jul 23. PubMed PMID: 30038008; PubMed Central  PMCID: PMC6094108.

 

Boisen ML, Hartnett JN, Shaffer JG, Goba A, Momoh M, Sandi JD, Fullah M, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Koval AP, Cross RW, Barnes KG,

Lachenauer AE, Lin AE, Nekoui M, Kotliar D, Winnicki SM, Siddle KJ, Gbakie M, Fonnie M, Koroma VJ, Kanneh L, Kulakosky PC, Hastie KM, Wilson RB, Andersen KG, Folarin OO, Happi CT, Sabeti PC, Geisbert TW, Saphire EO, Khan SH, Grant DS, Schieffelin JS, Branco LM, Garry RF. Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever. Sci Rep. 2018 Apr 12;8(1):5939. doi: 10.1038/s41598-018-24246-w. PubMed PMID: 29651117; PubMed Central PMCID:

PMC5897328.

 

Tewhey R, Kotliar D, Park DS, Liu B, Winnicki S, Reilly SK, Andersen KG, Mikkelsen TS, Lander ES, Schaffner SF, Sabeti PC. Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay. Cell. 2018 Feb 22;172(5):1132-1134. doi: 10.1016/j.cell.2018.02.021. PubMed PMID: 29474912.

 

Nguyen HV, Dong J, Panchakshari RA, Kumar V, Alt FW, Bories JC. Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch

region during class switch recombination. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10560-E10567. doi: 10.1073/pnas.1701366114. Epub 2017 Nov 20. PubMed PMID: 29158395; PubMed Central PMCID: PMC5724247.

 

Panchakshari RA, Zhang X, Kumar V, Du Z, Wei PC, Kao J, Dong J, Alt FW. DNA double-strand break response factors influence end-joining features of IgH class

switch and general translocation junctions. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):762-767. doi: 10.1073/pnas.1719988115. Epub 2018 Jan 8. PubMed PMID: 29311308; PubMed Central PMCID: PMC5789958.

 

Shao P, Seiler TG, Eltony AM, Ramier A, Kwok SJJ, Scarcelli G, Ii RP, Yun SH.  Effects of Corneal Hydration on Brillouin Microscopy In Vivo. Invest Ophthalmol

Vis Sci. 2018 Jun 1;59(7):3020-3027. doi: 10.1167/iovs.18-24228. PubMed PMID: 30025137; PubMed Central PMCID: PMC5995485

 

Kwok SJJ, Jo Y, Lin HH, Choi M, Yun SH. Millisecond cellular labelling in situ with two-photon photoconversion. Biomed Opt Express. 2018 Jun 11;9(7):3067-3077.  doi: 10.1364/BOE.9.003067. eCollection 2018 Jul 1. PubMed PMID: 29984083; PubMed  Central PMCID: PMC6033565.

 

Lu X, Fernando T, Lossos C, Yusufova N, Liu F, Fontán L, Durant M, Geng H, Melnick J, Luo Y, Vega F, Moy V, Inghirami G, Nimer S, Melnick AM, Lossos IS. PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival. Blood. 2018 Aug 6. pii: blood-2018-02-831438. doi: 10.1182/blood-2018-02-831438. [Epub ahead of print] PubMed PMID: 30082494.

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Yamauchi T, Masuda T, Canver MC, Seiler M, Semba Y, Shboul M, Al-Raqad M, Maeda M, Schoonenberg VAC, Cole MA, Macias-Trevino C, Ishikawa Y, Yao Q, Nakano M, Arai F, Orkin SH, Reversade B, Buonamici S, Pinello L, Akashi K, Bauer DE, Maeda T. Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS. Cancer Cell. 2018 Mar 12;33(3):386-400.e5. doi: 10.1016/j.ccell.2018.01.012. Epub 2018 Feb 22. PubMed PMID: 29478914; PubMed Central PMCID: PMC5849534.

 

Liu N, Hargreaves VV, Zhu Q, Kurland JV, Hong J, Kim W, Sher F, Macias-Trevino C, Rogers JM, Kurita R, Nakamura Y, Yuan GC, Bauer DE, Xu J, Bulyk ML, Orkin SH.

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch. Cell. 2018 Apr 5;173(2):430-442.e17. doi: 10.1016/j.cell.2018.03.016.

Epub 2018 Mar 29. PubMed PMID: 29606353; PubMed Central PMCID: PMC5889339.

 

Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch

C. Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes. Cell. 2018 Oct 18. pii: S0092-8674(18)31244-3. doi:

10.1016/j.cell.2018.09.032. [Epub ahead of print] PubMed PMID: 30343899.

 

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow

HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C. A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex

perturbation. Nat Cell Biol. 2018 Nov 5. doi: 10.1038/s41556-018-0221-1. [Epub ahead of print] PubMed PMID: 30397315.

 

Forget MA, Haymaker C, Hess KR, Meng YJ, Creasy C, Karpinets T, Fulbright OJ,  Roszik J, Woodman SE, Kim YU, Sakellariou-Thompson D, Bhatta A, Wahl A, Flores E,

Thorsen ST, Tavera RJ, Ramachandran R, Gonzalez AM, Toth CL, Wardell S, Mansaray  R, Patel V, Carpio DJ, Vaughn C, Farinas CM, Velasquez PG, Hwu WJ, Patel SP, Davies MA, Diab A, Glitza IC, Tawbi H, Wong MK, Cain S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Wargo JA, Radvanyi LG, Torres-Cabala CA, Beroukhim R, Hwu P, Amaria RN, Bernatchez C. Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response,  Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome. Clin Cancer Res. 2018 Sep 15;24(18):4416-4428. doi: 10.1158/1078-0432.CCR-17-3649. Epub 2018  May 30. PubMed PMID: 29848573; PubMed Central PMCID: PMC6139043.

 

Escudero S, Zaganjor E, Lee S, Mill CP, Morgan AM, Crawford EB, Chen J, Wales  TE, Mourtada R, Luccarelli J, Bird GH, Steidl U, Engen JR, Haigis MC, Opferman

JT, Walensky LD. Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD. Mol Cell. 2018

Mar 1;69(5):729-743.e7. doi: 10.1016/j.molcel.2018.02.005. PubMed PMID: 29499131;

PubMed Central PMCID: PMC5916823.

 

Stolte B, Iniguez AB, Dharia NV, Robichaud AL, Conway AS, Morgan AM, Alexe G,  Schauer NJ, Liu X, Bird GH, Tsherniak A, Vazquez F, Buhrlage SJ, Walensky LD,

Stegmaier K. Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. J Exp Med. 2018 Aug 6;215(8):2137-2155. doi:

10.1084/jem.20171066. Epub 2018 Jul 25. PubMed PMID: 30045945; PubMed Central PMCID: PMC6080915.

 

Cheadle L, Tzeng CP, Kalish BT, Harmin DA, Rivera S, Ling E, Nagy MA, Hrvatin  S, Hu L, Stroud H, Burkly LC, Chen C, Greenberg ME. Visual Experience-Dependent

Expression of Fn14 Is Required for Retinogeniculate Refinement. Neuron. 2018 Aug  8;99(3):525-539.e10. doi: 10.1016/j.neuron.2018.06.036. Epub 2018 Jul 19. PubMed

PMID: 30033152; PubMed Central PMCID: PMC6101651.

 

Kalish BT, Cheadle L, Hrvatin S, Nagy MA, Rivera S, Crow M, Gillis J, Kirchner R, Greenberg ME. Single-cell transcriptomics of the developing lateral geniculate

nucleus reveals insights into circuit assembly and refinement. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E1051-E1060. doi: 10.1073/pnas.1717871115. Epub 2018

Jan 17. PubMed PMID: 29343640; PubMed Central PMCID: PMC5798372.

 

Hrvatin S, Hochbaum DR, Nagy MA, Cicconet M, Robertson K, Cheadle L, Zilionis  R, Ratner A, Borges-Monroy R, Klein AM, Sabatini BL, Greenberg ME. Single-cell

analysis of experience-dependent transcriptomic states in the mouse visual cortex. Nat Neurosci. 2018 Jan;21(1):120-129. doi: 10.1038/s41593-017-0029-5.

Epub 2017 Dec 11. Erratum in: Nat Neurosci. 2018 May 11;:. PubMed PMID: 29230054; PubMed Central PMCID: PMC5742025.

 

Pradier B, Lanning K, Taljan KT, Feuille CJ, Nagy MA, Kauer JA. Persistent but Labile Synaptic Plasticity at Excitatory Synapses. J Neurosci. 2018 Jun

20;38(25):5750-5758. doi: 10.1523/JNEUROSCI.2772-17.2018. Epub 2018 May 25. PubMed PMID: 29802202; PubMed Central PMCID: PMC6010561.

 

Claw KG, Anderson MZ, Begay RL, Tsosie KS, Fox K, Garrison NA, (Nakatsuka, N); Summer internship for INdigenous peoples in Genomics (SING) Consortium. A framework for  enhancing ethical genomic research with Indigenous communities. Nat Commun. 2018  Jul 27;9(1):2957. doi: 10.1038/s41467-018-05188-3. Review. PubMed PMID: 30054469; PubMed Central PMCID: PMC6063854.

 

Bardill J, Bader AC, Garrison NA, Bolnick DA, Raff JA, Walker A, Malhi RS,  (Nakatsuka, N);Summer internship for INdigenous peoples in Genomics (SING) Consortium. Advancingthe ethics of paleogenomics. Science. 2018 Apr 27;360(6387):384-385. doi: 10.1126/science.aaq1131. Epub 2018 Apr 26. PubMed PMID: 29700256; PubMed Central PMCID: PMC6150602.

 

Posth C*, Nakatsuka N*, Lazaridis I, Skoglund P, Mallick S, Lamnidis TC, Rohland N, Nägele K, Adamski N, Bertolini E, Broomandkhoshbacht N, Cooper A, Culleton BJ,

Ferraz T, Ferry M, Furtwängler A, Haak W, Harkins K, Harper TK, Hünemeier T, Lawson AM, Llamas B, Michel M, Nelson E, Oppenheimer J, Patterson N, Schiffels S,

Sedig J, Stewardson K, Talamo S, Wang CC, Hublin JJ, Hubbe M, Harvati K, Nuevo Delaunay A, Beier J, Francken M, Kaulicke P, Reyes-Centeno H, Rademaker K, Trask

WR, Robinson M, Gutierrez SM, Prufer KM, Salazar-García DC, Chim EN, Müller Plumm, Gomes L, Alves ML, Liryo A, Inglez M, Oliveira RE, Bernardo DV, Barioni A,

Wesolowski V, Scheifler NA, Rivera MA, Plens CR, Messineo PG, Figuti L, Corach D, Scabuzzo C, Eggers S, DeBlasis P, Reindel M, Méndez C, Politis G, Tomasto-Cagigao

E, Kennett DJ, Strauss A, Fehren-Schmitz L, Krause J, Reich D. Reconstructing the Deep Population History of Central and South America. Cell. 2018 Nov 8. pii:

S0092-8674(18)31380-1. doi: 10.1016/j.cell.2018.10.027. [Epub ahead of print] PubMed PMID: 30415837.

 

Bourdeau RW, Lee-Gosselin A, Lakshmanan A, Farhadi A, Kumar SR, Nety SP, Shapiro MG. Acoustic reporter genes for noninvasive imaging of microorganisms in

mammalian hosts. Nature. 2018 Jan 3;553(7686):86-90. doi: 10.1038/nature25021. PubMed PMID: 29300010; PubMed Central PMCID: PMC5920530.

 

Kponee KZ, Nwanaji-Enwerem JC, Fu X, Kakulu II, Weisskopf MG, Jia C. Elevated  Indoor Volatile Organic Compound Exposure in the Niger Delta Region of Nigeria.

Int J Environ Res Public Health. 2018 Sep 6;15(9). pii: E1939. doi: 10.3390/ijerph15091939. PubMed PMID: 30200602; PubMed Central PMCID: PMC6164300.

 

Nwanaji-Enwerem JC, Wang W, Nwanaji-Enwerem O, Vokonas P, Baccarelli A, Weisskopf M, Herndon LW, Wiggs JL, Park SK, Schwartz J. Association of Long-term

Ambient Black Carbon Exposure and Oxidative Stress Allelic Variants With Intraocular Pressure in Older Men. JAMA Ophthalmol. 2018 Nov 8. doi:

10.1001/jamaophthalmol.2018.5313. [Epub ahead of print] PubMed PMID: 30419128

 

Gao X, Colicino E, Shen J, Just AC, Nwanaji-Enwerem JC, Coull B, Lin X, Vokonas P, Zheng Y, Hou L, Schwartz J, Baccarelli AA. Accelerated DNA methylation

age and the use of antihypertensive medication among older adults. Aging (Albany  NY). 2018 Nov 10. doi: 10.18632/aging.101626. [Epub ahead of print] PubMed PMID:

30414594.

 

Carmona JJ, Barfield RT, Panni T, Nwanaji-Enwerem JC, Just AC, Hutchinson JN,  Colicino E, Karrasch S, Wahl S, Kunze S, Jafari N, Zheng Y, Hou L, DeMeo DL,

Litonjua AA, Vokonas PS, Peters A, Lin X, Schwartz J, Schulz H, Baccarelli AA. Metastable DNA methylation sites associated with longitudinal lung function

decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts. Epigenetics. 2018 Oct 21:1-17. doi: 10.1080/15592294.2018.1529849. [Epub ahead of

print] PubMed PMID: 30343628.

 

Nwanaji-Enwerem JC, Cardenas A, Chai PR, Weisskopf MG, Baccarelli AA, Boyer EW. Relationships of Long-term Smoking and Moist Snuff Consumption with a DNA

Methylation Age Relevant Smoking Index: An Analysis in Buccal Cells. Nicotine Tob Res. 2018 Jul 21. doi: 10.1093/ntr/nty156. [Epub ahead of print] PubMed PMID:

30053132.

 

Dhingra R, Nwanaji-Enwerem JC, Samet M, Ward-Caviness CK. DNA Methylation Age-Environmental Influences, Health Impacts, and Its Role in Environmental

Epidemiology. Curr Environ Health Rep. 2018 Sep;5(3):317-327. doi: 10.1007/s40572-018-0203-2. Review. PubMed PMID: 30047075; PubMed Central PMCID: PMC6173330.

 

Nwanaji-Enwerem JC, Weisskopf MG, Baccarelli AA. Multi-tissue DNA methylation  age: Molecular relationships and perspectives for advancing biomarker utility.

Ageing Res Rev. 2018 Aug;45:15-23. doi: 10.1016/j.arr.2018.04.005. Epub 2018 Apr  23. Review. PubMed PMID: 29698722; PubMed Central PMCID: PMC6047923.

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Elfiky AA, Pany MJ, Parikh RB, Obermeyer Z. Development and Application of a Machine Learning Approach to Assess Short-term Mortality Risk Among Patients With Cancer Starting Chemotherapy. JAMA Network Open. 2018;1(3):e180926. doi:10.1001/jamanetworkopen.2018.0926.

 

Rodriguez-Fraticelli AE, Wolock SL, Weinreb CS, Panero R, Patel SH, Jankovic M, Sun J, Calogero RA, Klein AM, Camargo FD. Clonal analysis of lineage fate in

native haematopoiesis. Nature. 2018 Jan 11;553(7687):212-216. doi: 10.1038/nature25168. Epub 2018 Jan 3. PubMed PMID: 29323290; PubMed Central

PMCID: PMC5884107.

 

Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W,  Heffron GJ, Daley GQ, Sliz P. Small-Molecule Inhibitors Disrupt let-7

Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018 Jun 5;23(10):3091-3101. doi: 10.1016/j.celrep.2018.04.116. PubMed

PMID: 29874593.

 

Fung V, Peitzman CGK, Shi J, Liang CY, Dow WH, Zaslavsky AM, Fireman BH, Derose SF, Chernew ME, Newhouse JP, Hsu J. Adverse Selection into and within the

Individual Health Insurance Market in California in 2014. Health Serv Res. 2018 Oct;53(5):3750-3769. doi: 10.1111/1475-6773.12868. Epub 2018 May 17. PubMed PMID: 29774534; PubMed Central PMCID: PMC6153153.

 

Wang X, Raghavan A, Peters DT, Pashos EE, Rader DJ, Musunuru K. Interrogation  of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human

Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice. Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):76-82. doi:

10.1161/ATVBAHA.117.310103. Epub 2017 Nov 2. PubMed PMID: 29097363; PubMed Central PMCID: PMC5746470.

 

Koch R, Christie AL, Crombie JL, Palmer AC, Plana D, Shigemori K, Morrow SN, Van Scoyk A, Wu W, Brem EA, Secrist JP, Drew L, Schuller A, Cidado J, Letai A,

Weinstock DM. Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas.  Blood. 2018 Nov 29. pii: blood-2018-07-865527. doi: 10.1182/blood-2018-07-865527.[Epub ahead of print] PubMed PMID: 30498064

 

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S,  Palamara PF, Pinello L, Patterson N, Adams RP, Price AL. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk. Nat Genet. 2018 Oct;50(10):1483-1493. doi: 10.1038/s41588-018-0196-7. Epub 2018 Sep 3. PubMed PMID: 30177862; PubMed Central PMCID: PMC6202062.

 

Loh PR, Genovese G, Handsaker RE, Finucane HK, Reshef YA, Palamara PF, Birmann BM, Talkowski ME, Bakhoum SF, McCarroll SA, Price AL. Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations. Nature. 2018 Jul;559(7714):350-355. doi: 10.1038/s41586-018-0321-x. Epub 2018 Jul 11. PubMed PMID: 29995854; PubMed Central PMCID: PMC6054542.

 

Hormozdiari F, Gazal S, van de Geijn B, Finucane HK, Ju CJ, Loh PR, Schoech A, Reshef Y, Liu X, O'Connor L, Gusev A, Eskin E, Price AL. Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits. Nat Genet. 2018 Jul;50(7):1041-1047. doi: 10.1038/s41588-018-0148-2. Epub 2018 Jun 25. PubMed PMID: 29942083; PubMed Central PMCID: PMC6030458.

 

Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A; Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S,  Neale BM, Ophoff RA, O'Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nat

Genet. 2018 Apr;50(4):538-548. doi: 10.1038/s41588-018-0092-1. Epub 2018 Apr 9. PubMed PMID: 29632383; PubMed Central PMCID: PMC5942893.

 

Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S,  Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium, Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL. Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nat Genet.

2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9. PubMed PMID: 29632380; PubMed Central PMCID: PMC5896795.

 

Kelley DR, Reshef YA, Bileschi M, Belanger D, McLean CY, Snoek J. Sequential regulatory activity prediction across chromosomes with convolutional neural networks. Genome Res. 2018 May;28(5):739-750. doi: 10.1101/gr.227819.117. Epub 2018 Mar 27. PubMed PMID: 29588361; PubMed Central PMCID: PMC5932613.

 

Rodin RE, Walsh CA. Somatic Mutation in Pediatric Neurological Diseases. Pediatr Neurol. 2018 Aug 11. pii: S0887-8994(18)30858-0. doi: 10.1016/j.pediatrneurol.2018.08.008. [Epub ahead of print] Review. PubMed PMID: 30249355.

 

McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG Jr. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell. 2018 Sep 20;175(1):101-116.e25. doi: 10.1016/j.cell.2018.08.038. Epub 2018 Sep 13. PubMed  PMID: 30220459; PubMed Central PMCID: PMC6219629.

 

Sievers QL, Petzold G, Bunker RD, Renneville A, Słabicki M, Liddicoat BJ, Abdulrahman W, Mikkelsen T, Ebert BL, Thomä NH. Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science. 2018 Nov 2;362(6414). pii: eaat0572. doi: 10.1126/science.aat0572. PubMed PMID: 30385546.

 

Sievers QL, Gasser JA, Cowley GS, Fischer ES, Ebert BL. Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent

CRL4(CRBN) activity. Blood. 2018 Sep 20;132(12):1293-1303. doi: 10.1182/blood-2018-01-821769. Epub 2018 Jul 24. PubMed PMID: 30042095; PubMed Central PMCID: PMC6148446.

 

Starkweather CK, Gershman SJ, Uchida N. The Medial Prefrontal Cortex Shapes Dopamine Reward Prediction Errors under State Uncertainty. Neuron. 2018 May

2;98(3):616-629.e6. doi: 10.1016/j.neuron.2018.03.036. Epub 2018 Apr 12. PubMed PMID: 29656872; PubMed Central PMCID: PMC5934341.

 

Steinhorn B, Sorrentino A, Badole S, Bogdanova Y, Belousov V, Michel T. Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac  dysfunction. Nat Commun. 2018 Oct 2;9(1):4044. doi: 10.1038/s41467-018-06533-2. PubMed PMID: 30279532; PubMed Central PMCID: PMC6168530.

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Gurry T; HST Microbiome Consortium*, Gibbons SM, Nguyen LTT, Kearney SM, Ananthakrishnan A, Jiang X, Duvallet C, Kassam Z, Alm EJ. *Collaborators: Dannenberg PH, Finlayson SG, Hughes TK, Macias-Trevino C, Owusu-Boaitey K, Shomorony A, Tuang SL, Valenstein ML, Wang KK, Wu MP, Zack TI. Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort. Sci Rep. 2018 Aug 23;8(1):12699. doi: 10.1038/s41598-018-30783-1. PubMed PMID: 30139999; PubMed Central PMCID: PMC6107591

 

Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes. Nature. 2018 Apr 5;556(7699):64-69. doi: 10.1038/nature26158. Epub 2018 Mar 28. PubMed PMID: 29590090; PubMed Central PMCID: PMC5975964.

 

Wala JA, Bandopadhayay P, Greenwald NF, O'Rourke R, Sharpe T, Stewart C, Schumacher S, Li Y, Weischenfeldt J, Yao X, Nusbaum C, Campbell P, Getz G, Meyerson M, Zhang CZ, Imielinski M, Beroukhim R. SvABA: genome-wide detection of structural variants and indels by local assembly. Genome Res. 2018 Apr;28(4):581-591. doi: 10.1101/gr.221028.117. Epub 2018 Mar 13. PubMed PMID: 29535149; PubMed Central PMCID: PMC5880247.

 

Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, Taylor-Weiner A, Coughlin CA, Hess JM, Pedamallu CS, Livitz D, Rosebrock D, Rosenberg M, Tracy AA, Horn H, van Hummelen P, Feldman AL, Link BK,  Novak AJ, Cerhan JR, Habermann TM, Siebert R, Rosenwald A, Thorner AR, Meyerson ML, Golub TR, Beroukhim R, Wulf GG, Ott G, Rodig SJ, Monti S, Neuberg DS, Loeffler M, Pfreundschuh M, Trümper L, Getz G, Shipp MA. Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms  and outcomes. Nat Med. 2018 May;24(5):679-690. doi: 10.1038/s41591-018-0016-8. Epub 2018 Apr 30. Erratum in: Nat Med. 2018 Aug;24(8):1292. Nat Med. 2018 Aug;24(8):1290-1291. PubMed PMID: 29713087

 

Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala  NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M. Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing. Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18. PubMed PMID: 29909985; PubMed Central PMCID: PMC6046279.

 

Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, Taylor-Weiner A, Coughlin CA, Hess JM, Pedamallu CS, Livitz D, Rosebrock D, Rosenberg M, Tracy AA, Horn H, van Hummelen P, Feldman AL, Link BK,  Novak AJ, Cerhan JR, Habermann TM, Siebert R, Rosenwald A, Thorner AR, Meyerson ML, Golub TR, Beroukhim R, Wulf GG, Ott G, Rodig SJ, Monti S, Neuberg DS, Loeffler M, Pfreundschuh M, Trümper L, Getz G, Shipp MA. Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct  pathogenic mechanisms and outcomes. Nat Med. 2018 Aug;24(8):1292. doi: 10.1038/s41591-018-0098-3. PubMed PMID: 29955181.

 

Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, Taylor-Weiner A, Coughlin CA, Hess JM, Pedamallu CS, Livitz D, Rosebrock D, Rosenberg M, Tracy AA, Horn H, van Hummelen P, Feldman AL, Link BK, Novak AJ, Cerhan JR, Habermann TM, Siebert R, Rosenwald A, Thorner AR, Meyerson ML, Golub TR, Beroukhim R, Wulf GG, Ott G, Rodig SJ, Monti S, Neuberg DS, Loeffler M, Pfreundschuh M, Trümper L, Getz G, Shipp MA. Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct  pathogenic mechanisms and outcomes. Nat Med. 2018 Aug;24(8):1290-1291. doi: 10.1038/s41591-018-0097-4. PubMed PMID: 29955182.

 

Wen LS, Warren KE. Combatting the opioid epidemic: Baltimore's experience and  lessons learned. J Public Health (Oxf). 2018 Jun 1;40(2):e107-e111. doi: 10.1093/pubmed/fdx093. PubMed PMID: 28985362.

 

Jack HE, Warren KE, Sundaram S, Gheihman G, Weems J, Raja AS, Miller ES. Making Naloxone Rescue Part of Basic Life Support Training for Medical Students.  AEM Educ Train. 2018 Mar 30;2(2):174-177. doi: 10.1002/aet2.10095. eCollection 2018 Apr. PubMed PMID: 30051085; PubMed Central PMCID: PMC6001730

 

Shafee R, Nanda P, Padmanabhan JL, Tandon N, Alliey-Rodriguez N, Kalapurakkel  S, Weiner DJ, Gur RE, Keefe RSE, Hill SK, Bishop JR, Clementz BA, Tamminga CA, Gershon ES, Pearlson GD, Keshavan MS, Sweeney JA, McCarroll SA, Robinson EB. Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls. Transl Psychiatry. 2018 Apr 12;8(1):78. doi: 10.1038/s41398-018-0124-8. PubMed PMID: 29643358; PubMed Central PMCID: PMC5895806.

 

Haining WN, Weiss SA. c-Maf in CD4(+) T cells: it's all about context. Nat Immunol. 2018 May;19(5):429-431. doi: 10.1038/s41590-018-0087-1. Erratum in: Nat Immunol. 2018 Oct;19(10):1146. PubMed PMID: 29670237.

 

Hwang WL, Wolfson RL, Niemierko A, Marcus KJ, DuBois SG, Haas-Kogan D. Clinical Impact of Tumor Mutational Burden in Neuroblastoma. J Natl Cancer Inst.  2018 Oct 10. doi: 10.1093/jnci/djy157. [Epub ahead of print] PubMed PMID: 30307503.

 

Yuskaitis CJ, Jones BM, Wolfson RL, Super CE, Dhamne SC, Rotenberg A, Sabatini DM, Sahin M, Poduri A. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. Neurobiol Dis. 2018 Mar;111:91-101. doi:10.1016/j.nbd.2017.12.010. Epub 2017 Dec 20. PubMed PMID: 29274432; PubMed Central PMCID: PMC5803417.

 

Wyant GA, Abu-Remaileh M, Wolfson RL, Chen WW, Freinkman E, Danai LV, Vander Heiden MG, Sabatini DM. mTORC1 Activator SLC38A9 Is Required to Efflux Essential  Amino Acids from Lysosomes and Use Protein as a Nutrient. Cell. 2017 Oct 19;171(3):642-654.e12. doi: 10.1016/j.cell.2017.09.046. PubMed PMID: 29053970; PubMed Central PMCID: PMC5704964.

 

Yan WX, Chong S, Zhang H, Makarova KS, Koonin EV, Cheng DR, Scott DA. Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein. Mol Cell. 2018 Apr 19;70(2):327-339.e5.  doi: 10.1016/j.molcel.2018.02.028. Epub 2018 Mar 15. PubMed PMID: 29551514; PubMed Central PMCID: PMC5935466.

 

Moynihan KD, Holden RL, Mehta NK, Wang C, Karver MR, Dinter J, Liang S, Abraham W, Melo MB, Zhang AQ, Li N, Gall SL, Pentelute BL, Irvine DJ. Enhancement of Peptide Vaccine Immunogenicity by Increasing Lymphatic Drainage and Boosting Serum Stability. Cancer Immunol Res. 2018 Sep;6(9):1025-1038. doi: 10.1158/2326-6066.CIR-17-0607. Epub 2018 Jun 18. PubMed PMID: 29915023; PubMed Central PMCID: PMC6247902.

 

Olson CM, Jiang B, Erb MA, Liang Y, Doctor ZM, Zhang Z, Zhang T, Kwiatkowski N, Boukhali M, Green JL, Haas W, Nomanbhoy T, Fischer ES, Young RA, Bradner JE, Winter GE, Gray NS. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation. Nat Chem Biol. 2018 Feb;14(2):163-170. doi: 10.1038/nchembio.2538. Epub 2017 Dec 18. PubMed PMID: 29251720; PubMed Central PMCID: PMC5912898.

  

Douam F, Ziegler CGK, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska JM, Winer BY, Heller B, Shalek AK, Ploss A. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nat Commun. 2018 Nov 28;9(1):5031. doi: 10.1038/s41467-018-07478-2. PubMed PMID: 30487575; PubMed Central PMCID: PMC6262001.

 

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C. A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation. Nat Cell Biol. 2018 Dec;20(12):1410-1420. doi: 10.1038/s41556-018-0221-1. Epub 2018 Nov 5. PubMed PMID: 30397315.

 

Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch C. Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes. Cell. 2018 Nov 15;175(5):1272-1288.e20. doi: 10.1016/j.cell.2018.09.032. Epub 2018 Oct 18. PubMed PMID: 30343899.