Publications

2014

Konieczkowski DJ, Johannessen CM, Abudayyeh O, Kim JW, Cooper ZA, Piris A, Frederick DT, Barzily-Rokni M, Straussman R, Haq R, Fisher DE, Mesirov JP, Hahn WC, Flaherty KT, Wargo JA, Tamayo P, Garraway LA. A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discov. 2014 Apr 25. [Epub ahead of print] PubMed PMID: 24771846

Ferket BS, van Kempen BJ, Hunink MG, Agarwal I, Kavousi M, Franco OH, Steyerberg EW, Max W, Fleischmann KE. Predictive value of updating framingham risk scores with novel risk markers in the u.s. General population. PLoS One. 2014 Feb 18;9(2):e88312. doi: 10.1371/journal.pone.0088312. eCollection 2014. PMID:24558385

Agarwal I, Ide N, Ix JH, Kestenbaum B, Lanske B, Schiller NB, Whooley MA, Mukamal KJ. Fibroblast growth factor-23 and cardiac structure and function. J Am Heart Assoc. 2014 Feb 13;3(1):e000584. doi: 10.1161/JAHA.113.000584.PMID: 24525546

Agarwal I, Glazer NL, Barasch E, Biggs ML, Djoussé L, Fitzpatrick AL, Gottdiener JS, Ix JH, Kizer JR, Rimm EB, Siscovick DS, Tracy RP, Zieman SJ,
Mukamal KJ. Fibrosis-related biomarkers and risk of total and cause-specific mortality: the cardiovascular health study. Am J Epidemiol. 2014 Jun
1;179(11):1331-9. doi: 10.1093/aje/kwu067. Epub 2014 Apr 25. PubMed PMID: 24771724; PubMed Central PMCID: PMC4036218.

Wang SR, Agarwala V, Flannick J, Chiang CW, Altshuler D; GoT2D Consortium, Hirschhorn JN. Simulation of finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland. Am J Hum Genet. 2014 May 1;94(5):710-20. doi: 10.1016/j.ajhg.2014.03.019. Epub 2014 Apr 24. PubMed PMID: 24768551

Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT. Sensitizing protective tumor  microenvironments to antibody-mediated therapy. Cell. 2014 Jan 30;156(3):590-602. doi: 10.1016/j.cell.2013.12.041. PubMed PMID: 24485462; PubMed Central PMCID: PMC3975171.

Fahed AC, McDonough B, Gouvion CM, Newell KL, Dure LS, Bebin M, Bick AG, Seidman JG, Harter DH, Seidman CE. UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration. Ann Neurol. 2014 Apr 26. doi: 10.1002/ana.24164. [Epub ahead of print] PubMed PMID: 24771548.

Ito K, Bick AG, Flannick J, Friedman DJ, Genovese G, Parfenov MG, Depalma SR, Gupta N, Gabriel SB, Taylor HA Jr, Fox ER, Newton-Cheh C, Kathiresan S, Hirschhorn JN, Altshuler DM, Pollak MR, Wilson JG, Seidman JG, Seidman C. Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circ Res. 2014 Feb 28;114(5):845-50. doi: 10.1161/CIRCRESAHA.114.302347. Epub 2013 Dec 30. PubMed PMID: 24379297; PubMed Central PMCID: PMC3982584.

Canver MC. The figure one problem. IEEE Pulse. 2014 Mar-Apr;5(2):7. PubMed PMID: 24757755.

Chen AY, Deng Z, Billings AN, Seker UO, Lu MY, Citorik RJ, Zakeri B, Lu TK. Synthesis and patterning of tunable multiscale materials with engineered cells. Nat Mater. 2014 May;13(5):515-23. doi: 10.1038/nmat3912. Epub 2014 Mar 23. PubMed PMID: 24658114.

Chen WW, Birsoy K, Mihaylova MM, Snitkin H, Stasinski I, Yucel B, Bayraktar EC, Carette JE, Clish CB, Brummelkamp TR, Sabatini DD, Sabatini DM. Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells. Cell Rep. 2014 Apr 10;7(1):27-34. doi: 10.1016/j
celrep.2014.02.046. Epub 2014 Mar 27. PMID: 24685140

Birsoy K, Possemato R, Lorbeer FK, Bayraktar EC, Thiru P, Yucel B, Wang T, Chen WW, Clish CB, Sabatini DM. Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides. Nature. 2014 Apr 3;508(7494):108-12. doi: 10.1038/nature13110. Epub 2014 Mar 16.PMID:24670634

Chu Y, Fioravante D, Leitges M, Regehr WG. Calcium-Dependent PKC Isoforms Have Specialized Roles in Short-Term Synaptic Plasticity. Neuron. 2014 May 21;82(4):859-71. doi: 10.1016/j.neuron.2014.04.003. Epub 2014 May 1. PubMed PMID: 24794094.

Reiff RE, Ali BR, Baron B, Yu TW, Ben-Salem S, Coulter ME, Schubert CR, Hill RS, Akawi NA, Al-Younes B, Kaya N, Evrony GD, Al-Saffar M, Felie JM, Partlow JN, Sunu CM, Schembri-Wismayer P, Alkuraya FS, Meyer BF, Walsh CA, Al-Gazali L,
Mochida GH. METTL23, a transcriptional partner of GABPA, is essential for human cognition. Hum Mol Genet. 2014 Jul 1;23(13):3456-66. doi: 10.1093/hmg/ddu054. Epub 2014 Feb 5. PubMed PMID: 24501276; PubMed Central PMCID: PMC4049305

Jamuar SS, Lam AT, Kircher M, D'Gama AM, Wang J, Barry BJ, Zhang X, Hill RS, Partlow JN, Rozzo A, Servattalab S, Mehta BK, Topcu M, Amrom D, Andermann E, Dan B, Parrini E, Guerrini R, Scheffer IE, Berkovic SF, Leventer RJ, Shen Y, Wu BL,Barkovich AJ, Sahin M, Chang BS, Bamshad M, Nickerson DA, Shendure J, Poduri A,Yu TW, Walsh CA. Somatic mutations in cerebral cortical malformations. N Engl J Med. 2014 Aug 21;371(8):733-43. doi: 10.1056/NEJMoa1314432. PubMed PMID: 25140959

Das PP, Shao Z, Beyaz S, Apostolou E, Pinello L, De Los Angeles A, O'Brien K, Atsma JM, Fujiwara Y, Nguyen M, Ljuboja D, Guo G, Woo A, Yuan GC, Onder T, Daley  G, Hochedlinger K, Kim J, Orkin SH. Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity. Mol Cell. 2014 Jan 9;53(1):32-48. doi: 10.1016/j.molcel.2013.11.011. Epub 2013 Dec 19.PubMed PMID: 24361252; PubMed Central PMCID: PMC3919500.

Djordjevic, Darja. 2014. Accelerated Kigali. The Johannesburg Salon, Volume Seven. Gazit R, Mandal PK, Ebina W, Ben-Zvi A, Nombela-Arrieta C, Silberstein LE, Rossi DJ. Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J
Exp Med. 2014 Jun 23. pii: jem.20130428. [Epub ahead of print] PubMed PMID: 24958848.

Riddell J, Gazit R, Garrison BS, Guo G, Saadatpour A, Mandal PK, Ebina W, Volchkov P, Yuan GC, Orkin SH, Rossi DJ. Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. Cell. 2014 Apr 24;157(3):549-64. doi: 10.1016/j.cell.2014.04.006. PubMed PMID: 24766805; PubMed  Central PMCID: PMC4060823.

Sierra-Mercado D, Deckersbach T, Arulpragasam AR, Chou T, Rodman AM, Duffy A, McDonald EJ, Eckhardt CA, Corse AK, Kaur N, Eskandar EN, Dougherty DD. Decision making in avoidance-reward conflict: a paradigm for non-human primates and humans. Brain Struct Funct. 2014 Jun 27. [Epub ahead of print] PubMed PMID: 24969127.

Simon MV, Sheth SA, Eckhardt CA, Kilbride RD, Braver D, Williams Z, Curry W, Cahill D, Eskandar EN. Phase reversal technique decreases cortical stimulation time during motor mapping. J Clin Neurosci. 2014 Jun;21(6):1011-7. doi:
10.1016/j.jocn.2013.12.015. Epub 2014 Jan 29. PubMed PMID: 24679940.

Beyeler A, Eckhardt CA, Tye KM. Deciphering memory function with optogenetics. Prog Mol Biol Transl Sci. 2014;122:341-90. doi:10.1016/B978-0-12-420170-5.00012-X. PubMed PMID: 24484707.

Eshel N, Tian J. Dopamine gates sensory representations in cortex. J Neurophysiol. 2014 Jun 1;111(11):2161-3. doi: 10.1152/jn.00795.2013. Epub 2014 Jan 8. PMID: 24401705

Bae BI, Tietjen I, Atabay KD, Evrony GD, Johnson MB, Asare E, Wang PP, Murayama AY, Im K, Lisgo SN, Overman L, Šestan N, Chang BS, Barkovich AJ, Grant PE, Topçu M, Politsky J, Okano H, Piao X, Walsh CA. Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science. 2014 Feb 14;343(6172):764-8. doi: 10.1126/science.1244392. PubMed PMID: 24531968.

Reiff RE, Ali BR, Baron B, Yu TW, Ben-Salem S, Coulter ME, Schubert CR, Hill RS, Akawi NA, Al-Younes B, Kaya N, Evrony GD, Al-Saffar M, Felie JM, Partlow JN, Sunu CM, Schembri-Wismayer P, Alkuraya FS, Meyer BF, Walsh CA, Al-Gazali L,Mochida GH. METTL23, a transcriptional partner of GABPA, is essential for human cognition. Hum Mol Genet. 2014 Jul 1;23(13):3456-66. doi: 10.1093/hmg/ddu054. Epub 2014 Feb 5. PubMed PMID: 24501276; PubMed Central PMCID: PMC4049305.

Dreze M, Calkins AS, Gálicza J, Echelman DJ, Schnorenberg MR, Fell GL, Iwai S, Fisher DE, Szüts D, Iglehart JD, Lazaro JB. Monitoring Repair of UV-Induced 6-4-Photoproducts with a Purified DDB2 Protein Complex. PLoS One. 2014 Jan 28;9(1):e85896. doi: 10.1371/journal.pone.0085896. eCollection 2014. PMID: 24489677. PMCID: PMC3904869

Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. PMID: 24616378

van Teijlingen NH, Hölzemer A, Körner C, García-Beltrán WF, Schafer JL, Fadda L, Suscovich TJ, Brander C, Carrington M, Evans DT, van Baarle D, Altfeld M. Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03: 04 and modulate primary natural killer cell function. AIDS. 2014 Jun 19;28(10):1399-408. doi: 10.1097/QAD.0000000000000284. PubMed PMID: 24785948.

Bandopadhayay P, Bergthold G, Nguyen B, Schubert S, Gholamin S, Tang Y, Bolin S, Schumacher SE, Zeid R, Masoud S, Yu F, Vue N, Gibson WJ, Paolella BR, Mitra SS, Cheshier SH, Qi J, Liu KW, Wechsler-Reya R, Weiss WA, Swartling FJ, Kieran MW, Bradner JE, Beroukhim R, Cho YJ. BET bromodomain inhibition of MYC-amplified medulloblastoma. Clin Cancer Res. 2014 Feb 15;20(4):912-25. doi:10.1158/1078-0432.CCR-13-2281. Epub 2013 Dec 2. PubMed PMID: 24297863.

Gonzalez Castro LN, Hadjiosif AM, Hemphill MA, Smith MA. Environmental consistency determines the rate of motor adaptation. Curr Biol. 2014 May
19;24(10):1050-61. doi: 10.1016/j.cub.2014.03.049. Epub 2014 May 1. PubMed PMID: 24794296

Wu HG, Miyamoto YR, Gonzalez Castro LN, Ölveczky BP, Smith MA. Temporal structure of motor variability is dynamically regulated and predicts motor learning ability. Nat Neurosci. 2014 Feb;17(2):312-21. doi: 10.1038/nn.3616. Epub 2014 Jan 12. PubMed PMID: 24413700.

Vitti JJ, Grossman SR, Sabeti PC. Detecting natural selection in genomic data. Annu Rev Genet. 2013;47:97-120. doi: 10.1146/annurev-genet-111212-133526. Review. PubMed PMID: 24274750.

Lewis CA, Parker SJ, Fiske BP, McCloskey D, Gui DY, Green CR, Vokes NI, Feist AM, Vander Heiden MG, Metallo CM. Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells. Mol Cell. 2014 May 28. pii: S1097-2765(14)00402-X. doi: 10.1016/j.molcel.2014.05.008. [Epub ahead of print] PubMed PMID: 24882210.

Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13. PubMed PMID: 24530296; PubMed Central PMCID: PMC4006117.

Wagle N, Grabiner BC, Van Allen EM, Hodis E, Jacobus S, Supko JG, Stewart M, Choueiri TK, Gandhi L, Cleary JM, Elfiky AA, Taplin ME, Stack EC, Signoretti S, Loda M, Shapiro GI, Sabatini DM, Lander ES, Gabriel SB, Kantoff PW, Garraway LA, Rosenberg JE. Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib. Cancer Discov. 2014 May;4(5):546-53. doi: 10.1158/2159-8290.CD-13-0353. Epub 2014 Mar 13. PMID: 24625776

Wagle N, Van Allen EM, Treacy DJ, Frederick DT, Cooper ZA, Taylor-Weiner A, Rosenberg M, Goetz EM, Sullivan RJ, Farlow DN, Friedrich DC, Anderka K, Perrin D, Johannessen CM, McKenna A, Cibulskis K, Kryukov G, Hodis E, Lawrence DP, Fisher S, Getz G, Gabriel SB, Carter SL, Flaherty KT, Wargo JA, Garraway LA.  MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition. Cancer Discov. 2014 Jan;4(1):61-8. doi: 10.1158/2159-8290.CD-13-0631. Epub 2013 Nov 21. PMID: 24265154

Van Allen EM, Wagle N, Sucker A, Treacy DJ, Johannessen CM, Goetz EM, Place CS, Taylor-Weiner A, Whittaker S, Kryukov GV, Hodis E, Rosenberg M, McKenna A, Cibulskis K, Farlow D, Zimmer L, Hillen U, Gutzmer R, Goldinger SM, Ugurel S, Gogas HJ, Egberts F, Berking C, Trefzer U, Loquai C, Weide B, Hassel JC, Gabriel SB, Carter SL, Getz G, Garraway LA, Schadendorf D; Dermatologic Cooperative Oncology Group of Germany (DeCOG). The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma. Cancer Discov. 2014 Jan;4(1):94-109. doi: 10.1158/2159-8290.CD-13-0617. Epub 2013 Nov 21. PMID: 24265153

Slowikowski K, Hu X, Raychaudhuri S. SNPsea: an algorithm to identify cell types, tissues, and pathways affected by risk loci. Bioinformatics. 2014 May 10. [Epub ahead of print] PubMed PMID: 24813542.

Hu X, Kim H, Raj T, Brennan PJ, Trynka G, Teslovich N, Slowikowski K, Chen WM, Onengut S, Baecher-Allan C, De Jager PL, Rich SS, Stranger BE, Brenner MB, Raychaudhuri S. Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells. PLoS Genet. 2014 Jun 26;10(6):e1004404. doi: 10.1371/journal.pgen.1004404. eCollection 2014 Jun. PubMed PMID: 24968232.

Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13. PubMed PMID: 24530296; PubMed Central PMCID: PMC4006117.

Hwang WL*, Deindl S*, Harada BT, Zhuang X. Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA. Nature. 2014 Aug 14;512(7513):213-7. doi: 10.1038/nature13380. Epub 2014 Jun 29. PubMed PMID: 25043036; PubMed Central PMCID: PMC4134374

Konieczkowski DJ, Johannessen CM, Abudayyeh O, Kim JW, Cooper ZA, Piris A, Frederick DT, Barzily-Rokni M, Straussman R, Haq R, Fisher DE, Mesirov JP, Hahn WC, Flaherty KT, Wargo JA, Tamayo P, Garraway LA. A melanoma cell state
distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discov. 2014 Apr 25. [Epub ahead of print] PubMed PMID: 24771846

Kumar V, Alt FW, Oksenych V. Reprint of "Functional overlaps between XLF and the ATM-dependent DNA double strand break response". DNA Repair (Amst). 2014 May;17:52-63. doi: 10.1016/j.dnarep.2014.04.004. Epub 2014 Apr 24. PubMed PMID: 24767946.

Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science. 2014 May 2;344(6183):519-523. doi: 10.1126/science.1249547. PMID: 24786080

Lee MN*, Ye C*, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler D, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N . Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science. 2014 Mar 7;343(6175):1246980. doi: 10.1126/science.1246980. PMID: 24604203

Ashraf N, Bandiera O, Lee SL. Awards Unbundled: Evidence from a National Field Experiment. Journal of Economic Behavior and Organization. 2014 April (100): 44-63.

Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT. Sensitizing protective tumor microenvironments to antibody-mediated therapy. Cell. 2014 Jan 30;156(3):590-602. doi: 10.1016/j.cell.2013.12.041.PMID: 24485462; PMCID; PMC3975171.

Hung YP, Yellen G. Live-cell imaging of cytosolic NADH-NAD+ redox state using a genetically encoded fluorescent biosensor. Methods Mol Biol. 2014;1071:83-95. doi: 10.1007/978-1-62703-622-1_7. PMID: 24052382

Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA. Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discov. 2014 Jan 20. [Epub ahead of print] PMID: 24444711

Malik AN, Vierbuchen T, Hemberg M, Rubin AA, Ling E, Couch CH, Stroud H, Spiegel I, Farh KK, Harmin DA, Greenberg ME. Genome-wide identification and characterization of functional neuronal activity-dependent enhancers. Nat
Neurosci. 2014 Sep 7. doi: 10.1038/nn.3808. [Epub ahead of print] PubMed PMID: 25195102.

Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. PMID: 24616378

Strittmatter L, Li Y, Nakatsuka NJ, Calvo SE, Grabarek Z, Mootha VK. CLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activity. Hum Mol Genet. 2014 May 1;23(9):2313-23. doi: 10.1093/hmg/ddt624. Epub 2013 Dec 11. PubMed PMID: 24334609; PubMed Central PMCID: PMC3976331.

Guilinger JP, Pattanayak V, Reyon D, Tsai SQ, Sander JD, Joung JK, Liu DR. Broad specificity profiling of TALENs results in engineered nucleases with
improved DNA-cleavage specificity. Nat Methods. 2014 Apr;11(4):429-35. doi: 10.1038/nmeth.2845. Epub 2014 Feb 16. PubMed PMID: 24531420; PubMed Central PMCID: PMC4010127.

Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. PMID: 24616378

Reiff RE, Ali BR, Baron B, Yu TW, Ben-Salem S, Coulter ME, Schubert CR, Hill RS, Akawi NA, Al-Younes B, Kaya N, Evrony GD, Al-Saffar M, Felie JM, Partlow JN, Sunu CM, Schembri-Wismayer P, Alkuraya FS, Meyer BF, Walsh CA, Al-Gazali L, Mochida GH. METTL23, a transcriptional partner of GABPA, is essential for human cognition. Hum Mol Genet. 2014 Feb 19. [Epub ahead of print] PMID: 24501276

Sadegh C, Macklis JD. Established monolayer differentiation of mouse embryonic stem cells generates heterogeneous neocortical-like neurons stalled at a stage equivalent to midcorticogenesis. J Comp Neurol. 2014 Mar 8. doi: 10.1002/cne.23576. [Epub ahead of print] PubMed PMID: 24610556.

Schwartz AL, Sommers BD.  Moving for medicaid?  Recent eligibility expansions did not induce migration from other states. Health Aff (Millwood). 2014 Jan;33(1):88-94. doi: 10.1377/hlthaff.2013.0910. PubMed PMID: 24395939.

Shao DD, Xue W, Krall EB, Bhutkar A, Piccioni F, Wang X, Schinzel AC, Sood S, Rosenbluh J, Kim JW, Zwang Y, Roberts TM, Root DE, Jacks T, Hahn WC. KRAS and YAP1 Converge to Regulate EMT and Tumor Survival. Cell. 2014 Jul 3;158(1):171-84. doi: 10.1016/j.cell.2014.06.004. Epub 2014 Jun 19. PubMed PMID: 24954536

Chien AT, Song Z, Chernew ME, Landon BE, McNeil BJ, Safran DG, Schuster MA.  Two-year impact of the alternative quality contract on pediatric health care quality and spending. Pediatrics. 2014 Jan;133(1):96-104. doi: 10.1542/peds.2012-3440. Epub 2013 Dec 23. PMID: 24366988

Subtelny AO*, Eichhorn SW*, Chen GR, Sive H, Bartel DP. Poly(A)-tail profiling reveals an embryonic switch in translational control. Nature. 2014 Apr 3;508(7494):66-71. doi: 10.1038/nature13007. PMID: 24476825

van Schaik KD. A piece of my mind. Pimping Socrates. JAMA. 2014 Apr 9;311(14):1401-2. doi: 10.1001/jama.2014.2155. No abstract available. PMID: 24715073

van Schaik, K, and F Ruehli. 2014. Health is not always written in bone: using a modern comorbidity index to assess disease load in paleopathology. American Journal of Physical Anthropology 154: 215-221.

van Schaik, K. 2014. The ancient physician Galen, modern medicine, and the steri-strip debate. The Bariatric Times 11, no. 5: 14-15.

Hou JH, Venkatachalam V, Cohen AE. Temporal dynamics of microbial rhodopsin fluorescence reports absolute membrane voltage. Biophys J. 2014 Feb 4;106(3):639-48. doi: 10.1016/j.bpj.2013.11.4493. PMID: 24507604

Venkatachalam V, Brinks D, Maclaurin D, Hochbaum D, Kralj J, Cohen AE. Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin. J Am Chem Soc. 2014 Feb 12;136(6):2529-37. doi: 10.1021/ja411338t. Epub 2014 Jan 27. PMID:24428326

Park J, Werley CA, Venkatachalam V, Kralj JM, Dib-Hajj SD, Waxman SG, Cohen AE. Screening fluorescent voltage indicators with spontaneously spiking HEK cells. PLoS One. 2013 Dec 31;8(12):e85221. doi: 10.1371/journal.pone.0085221. eCollection 2013. PMID: 24391999. PMCID: PMC3877367.

Walker SR, Xiang M, Frank DA. STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b. Cancers (Basel). 2014 Apr 23;6(2):958-68. doi: 10.3390/cancers6020958. PubMed PMID: 24762632.

Walker SR, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou E, Elemento O, Cerchietti L, Melnick A, Frank DA. The transcriptional modulator BCL6 as a
molecular target for breast cancer therapy. Oncogene. 2014 Mar 24. doi: 10.1038/onc.2014.61. [Epub ahead of print] PubMed PMID: 24662818

Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA. STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal. 2014 Jan 28;7(310):ra11. doi: 10.1126/scisignal.2004497. PubMed PMID: 24473196.

Liu S, Walker SR, Nelson EA, Cerulli R, Xiang M, Toniolo PA, Qi J, Stone RM, Wadleigh M, Bradner JE, Frank DA. Targeting STAT5 in Hematologic Malignancies through Inhibition of the Bromodomain and Extra-Terminal (BET) Bromodomain Protein BRD2. Mol Cancer Ther. 2014 May;13(5):1194-205. doi: 10.1158/1535-7163.MCT-13-0341. Epub 2014 Jan 16. PubMed PMID: 24435449; PubMed Central PMCID: PMC4013223.

Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA. STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal. 2014 Jan 28;7(310):ra11. doi: 10.1126/scisignal.2004497. PMID: 24473196