Publications

2016

Sanguansak T, Morley K, Morley M, Kusakul S, Lee R, Shieh E, Yospaiboon Y, Bhoomibunchoo C, Chai-Ear S, Joseph A, Agarwal I. Comparing smartphone camera adapters in imaging post-operative cataract patients. J Telemed Telecare. 2016 Feb 4. pii: 1357633X15625400. [Epub ahead of print] PubMed PMID: 26851243.

 

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC, Stevens B, McCarroll SA. Schizophrenia risk from complex variation of complement  component 4. Nature. 2016 Jan 27. doi: 10.1038/nature16549. [Epub ahead of print] PubMed PMID: 26814963.

 

Masuda T, Wang X, Maeda M, Canver MC, Sher F, Funnell AP, Fisher C, Suciu M, Martyn GE, Norton LJ, Zhu C, Kurita R, Nakamura Y, Xu J, Higgs DR, Crossley M, Bauer DE, Orkin SH, Kharchenko PV, Maeda T. Transcription factors LRF and BCL11A  independently repress expression of fetal hemoglobin. Science. 2016 Jan 15;351(6270):285-9. doi: 10.1126/science.aad3312. PubMed PMID: 26816381.

 

Leung W, Shaffer CD, Reed LK, Smith ST, Barshop W, Dirkes W, Dothager M, Lee P, Wong J, Xiong D, Yuan H, Bedard JE, Machone JF, Patterson SD, Price AL, Turner BA, Knouse KA, et al. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. G3 (Bethesda). 2015 Mar 4;5(5):719-40. doi: 10.1534/g3.114.015966. PubMed PMID: 25740935; PubMed Central PMCID: PMC4426361.

 

Puram RV, Kowalczyk MS, de Boer CG, Schneider RK, Miller PG, McConkey M, Tothova Z, Tejero H, Heckl D, Järås M, Chen MC, Li H, Tamayo A, Cowley GS, Rozenblatt-Rosen O, Al-Shahrour F, Regev A, Ebert BL. Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML. Cell. 2016 Apr 7;165(2):303-16. doi: 10.1016/j.cell.2016.03.015. PubMed PMID: 27058663.

 

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC, Stevens B, McCarroll SA. Schizophrenia risk from complex variation of complement  component 4. Nature. 2016 Jan 27. doi: 10.1038/nature16549. [Epub ahead of print] PubMed PMID: 26814963.

 

 Saxton RA, Knockenhauer KE, Wolfson RL, Chantranupong L, Pacold ME, Wang T, Schwartz TU, Sabatini DM. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. Science. 2016 Jan 1;351(6268):53-8. doi: 10.1126/science.aad2087. Epub 2015 Nov 19. PubMed PMID: 26586190; PubMed Central  PMCID: PMC4698039

 

Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF, Richter J, Bernhart SH, Efeyan A, Iqbal S, Matthews J, Clear A, Guerra-Assunção JA, Bödör C, Quentmeier H, Mansbridge C, Johnson P, Davies A, Strefford JC, Packham G, Barrans S, Jack A, Du MQ, Calaminici M, Lister TA, Auer  R, Montoto S, Gribben JG, Siebert R, Chelala C, Zoncu R, Sabatini DM, Fitzgibbon  J. Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet. 2016 Feb;48(2):183-8. doi: 10.1038/ng.3473. Epub 2015 Dec 21. PubMed PMID: 26691987; PubMed Central PMCID: PMC4731318.

 

Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science. 2016 Jan

1;351(6268):84-8. doi: 10.1126/science.aad5227. Epub 2015 Dec 1. PubMed PMID: 26628643; PubMed Central PMCID: PMC4714946.

 

Tabebordbar M, Zhu K, Cheng JK, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Science. 2016 Jan  22;351(6271):407-11. doi: 10.1126/science.aad5177. Epub 2015 Dec 31. PubMed PMID: 26721686.

 

Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos RiveraRM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31. PubMed PMID: 26721684.

 

 

2015

Dahlman JE, Abudayyeh OO, Joung J, Gootenberg JS, Zhang F, Konermann S.Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease. Nat Biotechnol. 2015 Oct 5. doi: 10.1038/nbt.3390. [Epub ahead of print] PubMed PMID: 26436575.

 

Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F.  Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell. 2015 Sep 25. pii: S0092-8674(15)01200-3. doi: 10.1016/j.cell.2015.09.038. [Epub

ahead of print] PubMed PMID: 26422227.

 

Shmakov S, Abudayyeh OO, Makarova KS, Wolf YI, Gootenberg JS, Semenova E, Minakhin L, Joung J, Konermann S, Severinov K, Zhang F, Koonin EV. Discovery and  Functional Characterization of Diverse Class 2 CRISPR-Cas Systems. Mol Cell. 2015 Nov 5;60(3):385-97. doi: 10.1016/j.molcel.2015.10.008. Epub 2015 Oct 22. PubMed PMID: 26593719; PubMed Central PMCID: PMC4660269

 

Agarwal I, Glazer NL, Barasch E, Djousse L, Gottdiener JS, Ix JH, Kizer JR, Rimm EB, Siscovick DS, King GL, Mukamal KJ. Associations between metabolic dysregulation and circulating biomarkers of fibrosis: the Cardiovascular Health Study.Metabolism. 2015 Oct;64(10):1316-23. doi: 10.1016/j.metabol.2015.07.013. Epub 2015 Jul 21. PMID: 26282733

 

Ejaz S, Williamson DJ, Jensen-Kondering U, Ahmed T, Sawiak SJ, Baron JC. What is the Optimal Duration of Middle-Cerebral Artery Occlusion Consistently Resulting in Isolated Cortical Selective Neuronal Loss in the Spontaneously Hypertensive Rat? Front Neurol. 2015 Mar 26;6:64. doi: 10.3389/fneur.2015.00064.  eCollection 2015. PubMed PMID: 25859239; PubMed Central PMCID: PMC4374627.

 

Agarwal I, Arnold A, Glazer NL, Barasch E, Djousse L, Fitzpatrick AL, Gottdiener JS, Ix JH, Jensen RA, Kizer JR, Rimm EB, Siscovick DS, Tracy RP, Wong  TY, Mukamal KJ. Fibrosis-related biomarkers and large and small vessel disease: the Cardiovascular Health Study. Atherosclerosis. 2015 Apr;239(2):539-46. doi: 10.1016/j.atherosclerosis.2015.02.020. Epub 2015 Feb 16. PubMed PMID: 25725316.

 

Moutsianas L, Agarwala V, Fuchsberger C, Flannick J, Rivas MA, Gaulton KJ, Albers PK; GoT2D Consortium, McVean G, Boehnke M, Altshuler D, McCarthy MI. The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. PLoS Genet. 2015 Apr 23;11(4):e1005165. doi: 10.1371/journal.pgen.1005165. eCollection 2015 Apr. PubMed PMID: 25906071.

 

Nieh EH*, Matthews GA* , Allsop SA*, Presbrey KN, Leppla CA, Wichmann R, Neve R, Wildes CP, Tye KM. Decoding neural circuits that control compulsive sucrose seeking. Cell. 2015 Jan 29;160(3):528-41. doi: 10.1016/j.cell.2015.01.003. PubMed PMID: 25635460; PubMed Central PMCID: PMC4312417. (*co-first authors)

 

Goldberg JM, Fisher DE, Demetri GD, Neuberg D, Allsop SA, Fonseca C, Nakazaki  Y, Nemer D, Raut CP, George S, Morgan JA, Wagner AJ, Freeman GJ, Ritz J, Lezcano  C, Mihm M, Canning C, Hodi FS, Dranoff G. Biologic Activity of Autologous, Granulocyte-Macrophage Colony-Stimulating Factor Secreting Alveolar Soft-Part Sarcoma and Clear Cell Sarcoma Vaccines. Clin Cancer Res. 2015 Jul 15;21(14):3178-86. doi: 10.1158/1078-0432.CCR-14-2932. Epub 2015 Mar 24. PubMed PMID: 25805798; PubMed Central PMCID: PMC4506240.

 

Anahtar MN, Byrne EH, Doherty KE, Bowman BA, Yamamoto HS, Soumillon M, Padavattan N, Ismail N, Moodley A, Sabatini ME, Ghebremichael MS, Nusbaum C, Huttenhower C, Virgin HW, Ndung'u T, Dong KL, Walker BD, Fichorova RN, Kwon DS. Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract. Immunity. 2015 May 19;42(5):965-76. doi: 10.1016/j.immuni.2015.04.019. PubMed PMID: 25992865; PubMed Central PMCID: PMC4461369.

 

Byrne EH, Anahtar MN, Cohen KE, Moodley A, Padavattan N, Ismail N, Bowman BA,  Olson GS, Mabhula A, Leslie A, Ndung'u T, Walker BD, Ghebremichael MS, Dong KL, Kwon DS. Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study. Lancet Infect Dis. 2015 Dec 23. pii: S1473-3099(15)00429-6. doi: 10.1016/S1473-3099(15)00429-6. [Epub ahead of print]  PubMed PMID: 26723758

 

Andzelm MM, Cherry TJ, Harmin DA, Boeke AC, Lee C, Hemberg M, Pawlyk B, Malik  AN, Flavell SW, Sandberg MA, Raviola E, Greenberg ME. MEF2D Drives Photoreceptor  Development through a Genome-wide Competition for Tissue-Specific Enhancers. Neuron. 2015 Mar 18. pii: S0896-6273(15)00153-1. doi: 10.1016/j.neuron.2015.02.038. [Epub ahead of print] PubMed PMID: 25801704. PubMed Central PMCID: PMC4393375.

 

Bagley AF, Scherz-Shouval R, Galie PA, Zhang AQ, Wyckoff J, Whitesell L, Chen  CS, Lindquist S, Bhatia SN. Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors. Cancer Res. 2015 Aug 15;75(16):3255-67. doi:10.1158/0008-5472.CAN-15-0325. Epub 2015 Jun 29. PubMed PMID: 26122846.

 

Roberts AM, Ware JS, Herman DS, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh  R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, Flannick J, Gabriel SB, Altshuler DM, Macdonald PS, Heinig M, Keogh AM, Hayward CS, Banner NR, Pennell DJ, O'Regan DP, San TR, de Marvao A, Dawes TJ, Gulati A, Birks EJ, Yacoub MH, Radke M, Gotthardt M, Wilson JG, O'Donnell CJ, Prasad SK, Barton PJ, Fatkin D, Hubner N, Seidman JG, Seidman CE, Cook SA. Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med. 2015 Jan 14;7(270):270ra6. doi: 10.1126/scitranslmed.3010134. PubMed PMID: 25589632.

 

Billings N, Birjiniuk A, Samad TS, Doyle PS, Ribbeck K. Material properties of biofilms-a review of methods for understanding permeability and mechanics. Rep Prog Phys. 2015 Feb;78(3):036601. doi: 10.1088/0034-4885/78/3/036601. Epub 2015 Feb 26. PubMed PMID: 25719969; PubMed Central PMCID: PMC4504244

 

Blok NB, Tan D, Wang RY, Penczek PA, Baker D, DiMaio F, Rapoport TA, Walz T. Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4017-25. doi: 10.1073/pnas.1500257112. Epub 2015 Jul 13. PubMed PMID: 26170309; PubMed Central PMCID: PMC4522808.

 

Tan D, Blok NB, Rapoport TA, Walz T. Structures of the double-ring AAA ATPase  Pex1/Pex6 involved in peroxisome biogenesis. FEBS J. 2015 Oct 17. doi:

10.1111/febs.13569. [Epub ahead of print] Review. PubMed PMID: 26476099.

 

Song W, Cajigas I, Brown EN, Giszter SF. Adaptation to elastic loads and BMI robot controls during rat locomotion examined with point-process GLMs. Front Syst Neurosci. 2015 Apr 28;9:62. doi: 10.3389/fnsys.2015.00062. eCollection 2015. PubMed PMID: 25972789; PubMed Central PMCID: PMC4411868.

 

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA. miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction. Mol Ther. 2015 Jun 17. doi: 10.1038/mt.2015.113. [Epub ahead of print] PubMed PMID: 26080908.

 

Canver MC, Bauer DE, Orkin SH. Embryonic stem cells as sources of donor-independent platelets. J Clin Invest. 2015 Jun;125(6):2261-3. doi: 10.1172/JCI82348. Epub 2015 May 11. PubMed PMID: 25961451; PubMed Central PMCID:  PMC4497771.

 

Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp  PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. 2015 Sep 16. doi: 10.1038/nature15521. [Epub ahead of print] PubMed PMID: 26375006.

 

Lin MI, Price EN, Boatman S, Hagedorn EJ, Trompouki E, Satishchandran S, Carspecken CW, Uong A, DiBiase A, Yang S, Canver MC, Dahlberg A, Lu Z, Zhang CC,  Orkin SH, Bernstein ID, Aster JC, White RM, Zon LI. Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. Elife. 2015 Feb 25;4. doi: 10.7554/eLife.05544. PubMed PMID: 25714926; PubMed Central PMCID: PMC4371382.

 

Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL. EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression. Blood. 2015 Oct 15;126(16):1930-9. doi: 10.1182/blood-2015-06-649087. Epub 2015 Aug 28. PubMed PMID: 26320100; PubMed Central PMCID: PMC4608240.

 

Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, Choe J, Jun DL, Shen X, Gregory RI, Daley GQ, Meissner A, Kellis M, Hochedlinger K, Kim J, Orkin SH. PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. Cell Rep. 2015 Sep 1;12(9):1456-70. doi: 10.1016/j.celrep.2015.07.053. Epub 2015 Aug 20. PubMed PMID: 26299972.

 

Chen AY, Zhong C, Lu TK. Engineering living functional materials. ACS Synth Biol. 2015 Jan 16;4(1):8-11. doi: 10.1021/sb500113b. PubMed PMID: 25592034; PubMed Central PMCID: PMC4304442.

 

Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM. An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis. Cell. 2015 Jul 30;162(3):540-51.  doi: 10.1016/j.cell.2015.07.016. PubMed PMID: 26232224; PubMed Central PMCID: PMC4522279.

 

Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature. 2015 Apr 16;520(7547):363-7. doi: 10.1038/nature14363. Epub 2015 Apr 8. PubMed PMID: 25855294; PubMed Central PMCID: PMC4533874.

 

Katajisto P, Döhla J, Chaffer CL, Pentinmikko N, Marjanovic N, Iqbal S, Zoncu R, Chen W, Weinberg RA, Sabatini DM.Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness.  Science. 2015 Apr 17;348(6232):340-3. doi: 10.1126/science.1260384. Epub 2015 Apr 2. PMID: 25837514

 

Zürcher NR, Loggia ML, Lawson R, Chonde DB, Izquierdo-Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N. Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28. Neuroimage Clin. 2015 Jan 19;7:409-14. doi: 10.1016/j.nicl.2015.01.009. eCollection 2015. PubMed PMID: 25685708; PubMed Central PMCID: PMC4310932.

 

Loggia ML, Chonde DB, Akeju O, Arabasz G, Catana C, Edwards RR, Hill E, Hsu S, Izquierdo-Garcia D, Ji RR, Riley M, Wasan AD, Zürcher NR, Albrecht DS, Vangel MG, Rosen BR, Napadow V, Hooker JM. Evidence for brain glial activation in chronic pain patients. Brain. 2015 Mar;138(Pt 3):604-15. doi: 10.1093/brain/awu377. Epub  2015 Jan 12. PubMed PMID: 25582579; PubMed Central PMCID: PMC4339770.

 

Connor Y, Tekleab S, Nandakumar S, Walls C, Tekleab Y, Husain A, Gadish O,Sabbisetti V, Kaushik S, Sehrawat S, Kulkarni A, Dvorak H, Zetter B, R Edelman E,

Sengupta S. Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype. Nat Commun. 2015 Dec 16;6:8671. doi: 10.1038/ncomms9671. PubMed PMID: 26669454; PubMed Central PMCID:  PMC4697439.

 

 

Nakayama T, Al-Maawali A, El-Quessny M, Rajab A, Khalil S, Stoler JM, Tan WH,  Nasir R, Schmitz-Abe K, Hill RS, Partlow JN, Al-Saffar M, Servattalab S, LaCoursiere CM, Tambunan DE, Coulter ME, Elhosary PC, Gorski G, Barkovich AJ, Markianos K, Poduri A, Mochida GH. Mutations in PYCR2, Encoding

Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015 May 7;96(5):709-19. doi: 10.1016/j.ajhg.2015.03.003. Epub 2015 Apr 9. PubMed PMID: 25865492.

 

Ramanan V, Shlomai A, Cox DB, Schwartz RE, Michailidis E, Bhatta A, Scott DA,  Zhang F, Rice CM, Bhatia SN. CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus. Sci Rep. 2015 Jun 2;5:10833. doi: 10.1038/srep10833. PubMed PMID: 26035283.

 

Cox DB, Platt RJ, Zhang F. Therapeutic genome editing: prospects and challenges. Nat Med. 2015 Feb;21(2):121-31. doi: 10.1038/nm.3793. Review. PubMed  PMID: 25654603; PubMed Central PMCID: PMC4492683.

 

Lodato MA, Woodworth MB, Lee S, Evrony GD, Mehta BK, Karger A, Lee S, Chittenden TW, D'Gama AM, Cai X, Luquette LJ, Lee E, Park PJ, Walsh CA. Somatic mutation in single human neurons tracks developmental and transcriptional history. Science. 2015 Oct 2;350(6256):94-8. doi: 10.1126/science.aab1785. PubMed PMID: 26430121.

 

D'Gama AM, Geng Y, Couto JA, Martin B, Boyle EA, LaCoursiere CM, Hossain A, Hatem NE, Barry BJ, Kwiatkowski DJ, Vinters HV, Barkovich AJ, Shendure J, Mathern GW, Walsh CA, Poduri A. Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia. Ann Neurol. 2015 Apr;77(4):720-5. doi: 10.1002/ana.24357. Epub 2015 Feb 26. PubMed PMID: 25599672.

 

D'Gama AM, Pochareddy S, Li M, Jamuar SS, Reiff RE, Lam AT, Sestan N, Walsh CA. Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms. Neuron. 2015 Dec 2;88(5):910-7. doi: 10.1016/j.neuron.2015.11.009. PubMed PMID: 26637798; PubMed Central PMCID: PMC4672379.

 

Soria-Valles C, Osorio FG, Gutiérrez-Fernández A, De Los Angeles A, Bueno C, Menéndez P, Martín-Subero JI, Daley GQ, Freije JM, López-Otín C. NF-κB activation impairs somatic cell reprogramming in ageing. Nat Cell Biol. 2015 Aug;17(8):1004-13. doi: 10.1038/ncb3207. Epub 2015 Jul 27. PubMed PMID: 26214134.

 

Bazley FA, Liu CF, Yuan X, Hao H, All AH, De Los Angeles A, Zambidis ET, Gearhart JD, Kerr CL. Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells: Efficient Generation of Genetically Engineered Germ Cells. Stem Cells Dev. 2015 Aug 10. [Epub ahead of print] PubMed PMID:

26154167.

 

Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, Choe J, Jun DL, Shen X, Gregory RI, Daley GQ, Meissner A, Kellis M, Hochedlinger K, Kim J, Orkin SH. PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. Cell Rep. 12:1456-70 (2015). PMID: 26299972

 

De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ. Hallmarks of pluripotency. Nature. 525:469-78 (2015). PMID: 26399828

 

De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ. Failure to replicate the STAP cell phenomenon. Nature 525:E6-9 (2015). PMID: 26399835

 

De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant  J, Wernig M, Park PJ, Daley GQ. Corrigendum: Hallmarks of pluripotency. Nature. 2015 Dec 16. doi: 10.1038/nature16470. [Epub ahead of print] PubMed PMID: 26675727.

 

De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross  S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J,  Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ. Corrigendum: Failure to replicate the STAP cell phenomenon. Nature. 2015 Dec 16. doi: 10.1038/nature16479. [Epub ahead of print] PubMed PMID: 26675720.

 

Eisner A, Pazyra-Murphy MF, Durresi E, Zhou P, Zhao X, Chadwick EC, Xu PX, Hillman RT, Scott MP, Greenberg ME, Segal RA. The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis. Dev Cell. 2015 Apr 6;33(1):22-35. doi: 10.1016/j.devcel.2015.01.033. Epub 2015 Mar 26. PubMed PMID:  25816987; PubMed Central PMCID: PMC4418443

 

Ebina W, Rossi DJ. Transcription factor-mediated reprogramming toward hematopoietic stem cells. EMBO J. 2015 Mar 12;34(6):694-709. doi: 10.15252/embj.201490804. Epub 2015 Feb 20. Review. PubMed PMID: 25712209; PubMed  Central PMCID: PMC4369309.

 

Eshel N, Bukwich M, Rao V, Hemmelder V, Tian J, Uchida N. Arithmetic and local circuitry underlying dopamine prediction errors. Nature. 2015 Aug 31. doi: 10.1038/nature14855. [Epub ahead of print] PubMed PMID: 26322583.

 

Eshel N, Bukwich M, Rao V, Hemmelder V, Tian J, Uchida N. Erratum: Arithmetic and local circuitry underlying dopamine prediction errors. Nature. 2015 Oct 7.

doi: 10.1038/nature15718. [Epub ahead of print] PubMed PMID: 26444234.

 

Everett KD, Conway C, Desany GJ, Baker BL, Choi G, Taylor CA, Edelman ER. Structural Mechanics Predictions Relating to Clinical Coronary Stent Fracture in  a 5 Year Period in FDA MAUDE Database. Ann Biomed Eng. 2015 Oct 14. [Epub ahead of print] PubMed PMID: 26467552

 

Lodato MA, Woodworth MB, Lee S, Evrony GD, Mehta BK, Karger A, Lee S, Chittenden TW, D'Gama AM, Cai X, Luquette LJ, Lee E, Park PJ, Walsh CA. Somatic mutation in single human neurons tracks developmental and transcriptional history. Science. 2015 Oct 2;350(6256):94-8. doi: 10.1126/science.aab1785. PubMed PMID: 26430121.

 

Ahmed MY, Chioza BA, Rajab A, Schmitz-Abe K, Al-Khayat A, Al-Turki S, Baple EL, Patton MA, Al-Memar AY, Hurles ME, Partlow JN, Hill RS, Evrony GD, Servattalab S, Markianos K, Walsh CA, Crosby AH, Mochida GH. Loss of PCLO function underlies pontocerebellar hypoplasia type III. Neurology. 2015 Apr

28;84(17):1745-50. doi: 10.1212/WNL.0000000000001523. Epub 2015 Apr 1. PubMed PMID: 25832664; PubMed Central PMCID: PMC4424132

 

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