Publications

2014

Konieczkowski DJ, Johannessen CM, Abudayyeh O, Kim JW, Cooper ZA, Piris A, Frederick DT, Barzily-Rokni M, Straussman R, Haq R, Fisher DE, Mesirov JP, Hahn WC, Flaherty KT, Wargo JA, Tamayo P, Garraway LA. A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discov. 2014 Apr 25. [Epub ahead of print] PubMed PMID: 24771846

Ferket BS, van Kempen BJ, Hunink MG, Agarwal I, Kavousi M, Franco OH, Steyerberg EW, Max W, Fleischmann KE. Predictive value of updating framingham risk scores with novel risk markers in the u.s. General population. PLoS One. 2014 Feb 18;9(2):e88312. doi: 10.1371/journal.pone.0088312. eCollection 2014. PMID:24558385

Agarwal I, Ide N, Ix JH, Kestenbaum B, Lanske B, Schiller NB, Whooley MA, Mukamal KJ. Fibroblast growth factor-23 and cardiac structure and function. J Am Heart Assoc. 2014 Feb 13;3(1):e000584. doi: 10.1161/JAHA.113.000584.PMID: 24525546

Agarwal I, Glazer NL, Barasch E, Biggs ML, Djoussé L, Fitzpatrick AL, Gottdiener JS, Ix JH, Kizer JR, Rimm EB, Siscovick DS, Tracy RP, Zieman SJ, Mukamal KJ. Fibrosis-related biomarkers and risk of total and cause-specific mortality: the cardiovascular health study. Am J Epidemiol. 2014 Jun 1;179(11):1331-9. doi: 10.1093/aje/kwu067. Epub 2014 Apr 25. PubMed PMID: 24771724; PubMed Central PMCID: PMC4036218.

Agarwal I, Glazer NL, Barasch E, Biggs ML, Djousse L, Fitzpatrick AL, Gottdiener JS, Ix JH, Kizer JR, Rimm EB, Sicovick DS, Tracy RP, Mukamal KJ. Fibrosis-related biomarkers and incident cardiovascular disease in older adults: the cardiovascular health study. Circ Arrhythm Electrophysiol. 2014 Aug;7(4):583-9. doi: 10.1161/CIRCEP.114.001610. Epub 2014 Jun 24. PubMed PMID: 24963008; PubMed Central PMCID: PMC4140969.

Jensen MK, Bertoia ML, Cahill LE, Agarwal I, Rimm EB, Mukamal KJ. Novel metabolic biomarkers of cardiovascular disease. Nat Rev Endocrinol. 2014 Nov;10(11):659-672. doi: 10.1038/nrendo.2014.155. Epub 2014 Sep 2. Review. PubMed PMID: 25178732

Wang SR, Agarwala V, Flannick J, Chiang CW, Altshuler D; GoT2D Consortium, Hirschhorn JN. Simulation of finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland. Am J Hum Genet. 2014 May 1;94(5):710-20. doi: 10.1016/j.ajhg.2014.03.019. Epub 2014 Apr 24. PubMed PMID: 24768551

Allsop SA, Vander Weele CM, Wichmann R, Tye KM. Optogenetic insights on the relationship between anxiety-related behaviors and social deficits. Front Behav Neurosci. 2014 Jul 16;8:241. doi: 10.3389/fnbeh.2014.00241. eCollection 2014. Review. PubMed PMID: 25076878; PubMed Central PMCID: PMC4099964.

Theurillat JP, Udeshi ND, Errington WJ, Svinkina T, Baca SC, Pop M, Wild PJ, Blattner M, Groner AC, Rubin MA, Moch H, Privé GG, Carr SA, Garraway LA. Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer. Science. 2014 Oct 3;346(6205):85-9. doi: 10.1126/science.1250255. Epub 2014 Oct 2. PubMed PMID: 25278611.

Prandi D, Baca SC, Romanel A, Barbieri CE, Mosquera J, Fontugne J, Beltran H, Sboner A, Garraway LA, Rubin MA, Demichelis F. Unraveling the clonal hierarchy of somatic genomic aberrations. Genome Biol. 2014 Aug 26;15(8):439. [Epub ahead of print] PubMed PMID: 25160065; PubMed Central PMCID: PMC4167267

Ghosh D*, Bagley AF*, Na YJ, Birrer MJ, Bhatia SN, Belcher AM. Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13948-53. doi: 10.1073/pnas.1400821111. Epub 2014 Sep 11. PubMed PMID: 25214538; PubMed Central PMCID: PMC4183329.

Pallasch CP, Leskov I, Braun CJ, Vorholt D, Drake A, Soto-Feliciano YM, Bent EH, Schwamb J, Iliopoulou B, Kutsch N, van Rooijen N, Frenzel LP, Wendtner CM, Heukamp L, Kreuzer KA, Hallek M, Chen J, Hemann MT. Sensitizing protective tumor  microenvironments to antibody-mediated therapy. Cell. 2014 Jan 30;156(3):590-602. doi: 10.1016/j.cell.2013.12.041. PubMed PMID: 24485462; PubMed Central PMCID: PMC3975171.

Fahed AC, McDonough B, Gouvion CM, Newell KL, Dure LS, Bebin M, Bick AG, Seidman JG, Harter DH, Seidman CE. UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration. Ann Neurol. 2014 Apr 26. doi: 10.1002/ana.24164. [Epub ahead of print] PubMed PMID: 24771548.

Ito K, Bick AG, Flannick J, Friedman DJ, Genovese G, Parfenov MG, Depalma SR, Gupta N, Gabriel SB, Taylor HA Jr, Fox ER, Newton-Cheh C, Kathiresan S, Hirschhorn JN, Altshuler DM, Pollak MR, Wilson JG, Seidman JG, Seidman C. Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circ Res. 2014 Feb 28;114(5):845-50. doi: 10.1161/CIRCRESAHA.114.302347. Epub 2013 Dec 30. PubMed PMID: 24379297; PubMed Central PMCID: PMC3982584.

Glessner J, Bick AG, Ito K, Homsy J, Rodriguez-Murillo L, Fromer M, Mazaika EJ, Vardarajan B, Italia MJ, Leipzig J, DePalma S, Golhar R, Sanders SJ, Yamrom B, Ronemus M, Iossifov I, Willsey AJ, State MW, Kaltman JR, White PS, Shen Y,
Warburton D, Brueckner M, Seidman C, Goldmuntz E, Gelb BD, Lifton R, Seidman JG, Hakonarson H, Chung WK. Increased Frequency of De Novo Copy Number Variations in Congenital Heart Disease by Integrative Analysis of SNP Array and Exome Sequence Data. Circ Res. 2014 Sep 9. pii: CIRCRESAHA.114.304458. [Epub ahead of print] PubMed PMID: 25205790.

Cereatti A, Calderone M, Buckland DM, Buettner A, Della Croce U, Rosso C. In vivo glenohumeral translation under anterior loading in an open-MRI set-up. J Biomech. 2014 Sep 28. pii: S0021-9290(14)00487-4. doi: 10.1016/j.jbiomech.2014.09.021. [Epub ahead of print] PubMed PMID: 25307436

Rosso C, Müller S, Buckland DM, Schwenk T, Zimmermann S, de Wild M, Valderrabano V. All-inside meniscal repair devices compared with their matched inside-out vertical mattress suture repair: introducing 10,000 and 100,000
loading cycles. Am J Sports Med. 2014 Sep;42(9):2226-33. doi: 10.1177/0363546514538394. Epub 2014 Jun 25. PubMed PMID: 24966304.

Kueckelhaus M, Philip J, Kamel RA, Canseco JA, Hackl F, Kiwanuka E, Kim MJ, Wilkie R, Caterson EJ, Junker JP, Eriksson E. Sustained release of amnion-derived cellular cytokine solution facilitates achilles tendon healing in rats. Eplasty.
2014 Aug 4;14:e29. eCollection 2014. PubMed PMID: 25210571; PubMed Central PMCID: PMC4124919.

Canver MC. The figure one problem. IEEE Pulse. 2014 Mar-Apr;5(2):7. PubMed PMID: 24757755.

Canver MC, Bauer DE, Dass A, Yien YY, Chung J, Masuda T, Maeda T, Paw BH, Orkin SH. Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in
mammalian cells. J Biol Chem. 2014 Aug 1;289(31):21312-24. doi: 10.1074/jbc.M114.564625. Epub 2014 Jun 6. PubMed PMID: 24907273; PubMed Central PMCID: PMC4118095

Chen AY, Deng Z, Billings AN, Seker UO, Lu MY, Citorik RJ, Zakeri B, Lu TK. Synthesis and patterning of tunable multiscale materials with engineered cells. Nat Mater. 2014 May;13(5):515-23. doi: 10.1038/nmat3912. Epub 2014 Mar 23. PubMed PMID: 24658114.

Chen WW, Birsoy K, Mihaylova MM, Snitkin H, Stasinski I, Yucel B, Bayraktar EC, Carette JE, Clish CB, Brummelkamp TR, Sabatini DD, Sabatini DM. Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells. Cell Rep. 2014 Apr 10;7(1):27-34. doi: 10.1016/j
celrep.2014.02.046. Epub 2014 Mar 27. PMID: 24685140

Birsoy K, Possemato R, Lorbeer FK, Bayraktar EC, Thiru P, Yucel B, Wang T, Chen WW, Clish CB, Sabatini DM. Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides. Nature. 2014 Apr 3;508(7494):108-12. doi: 10.1038/nature13110. Epub 2014 Mar 16.PMID:24670634

Izquierdo-Garcia D, Hansen AE, Förster S, Benoit D, Schachoff S, Fürst S, Chen KT, Chonde DB, Catana C. An SPM8-Based Approach for Attenuation Correction Combining Segmentation and Nonrigid Template Formation: Application to
Simultaneous PET/MR Brain Imaging. J Nucl Med. 2014 Nov;55(11):1825-30. doi: 10.2967/jnumed.113.136341. Epub 2014 Oct 2. PubMed PMID: 25278515.

Wey HY, Catana C, Hooker JM, Dougherty DD, Knudsen GM, Wang DJ, Chonde DB, Rosen BR, Gollub RL, Kong J. Simultaneous fMRI-PET of the opioidergic pain system in human brain. Neuroimage. 2014 Aug 6;102P2:275-282. doi: 10.1016/j.neuroimage.2014.07.058. [Epub ahead of print] PubMed PMID: 25107855.

Sander CY, Keil B, Chonde DB, Rosen BR, Catana C, Wald LL. A 31-channel MR brain array coil compatible with positron emission tomography. Magn Reson Med. 2014 Jul 7. doi: 10.1002/mrm.25335. [Epub ahead of print] PubMed PMID: 25046699.

Villien M, Wey HY, Mandeville JB, Catana C, Polimeni JR, Sander CY, Zürcher NR, Chonde DB, Fowler JS, Rosen BR, Hooker JM. Dynamic functional imaging of brain glucose utilization using fPET-FDG. Neuroimage. 2014 Oct 15;100:192-9. doi: 10.1016/j.neuroimage.2014.06.025. Epub 2014 Jun 14. PubMed PMID: 24936683; PubMed Central PMCID: PMC4224310

Poynton CB, Chen KT, Chonde DB, Izquierdo-Garcia D, Gollub RL, Gerstner ER, Batchelor TT, Catana C. Probabilistic atlas-based segmentation of combined T1-weighted and DUTE MRI for calculation of head attenuation maps in integrated
PET/MRI scanners. Am J Nucl Med Mol Imaging. 2014 Mar 20;4(2):160-71. eCollection 2014. PubMed PMID: 24753982; PubMed Central PMCID: PMC3992209.

Chu Y, Fioravante D, Leitges M, Regehr WG. Calcium-Dependent PKC Isoforms Have Specialized Roles in Short-Term Synaptic Plasticity. Neuron. 2014 May 21;82(4):859-71. doi: 10.1016/j.neuron.2014.04.003. Epub 2014 May 1. PubMed PMID: 24794094.

Fioravante D, Chu Y, de Jong AP, Leitges M, Kaeser PS, Regehr WG. Protein kinase C is a calcium sensor for presynaptic short-term plasticity. Elife. 2014 Aug 5;3:e03011. doi: 10.7554/eLife.03011. PubMed PMID: 25097249; PubMed Central PMCID: PMC4121671

Reiff RE, Ali BR, Baron B, Yu TW, Ben-Salem S, Coulter ME, Schubert CR, Hill RS, Akawi NA, Al-Younes B, Kaya N, Evrony GD, Al-Saffar M, Felie JM, Partlow JN, Sunu CM, Schembri-Wismayer P, Alkuraya FS, Meyer BF, Walsh CA, Al-Gazali L,
Mochida GH. METTL23, a transcriptional partner of GABPA, is essential for human cognition. Hum Mol Genet. 2014 Jul 1;23(13):3456-66. doi: 10.1093/hmg/ddu054. Epub 2014 Feb 5. PubMed PMID: 24501276; PubMed Central PMCID: PMC4049305

Jamuar SS, Lam AT, Kircher M, D'Gama AM, Wang J, Barry BJ, Zhang X, Hill RS, Partlow JN, Rozzo A, Servattalab S, Mehta BK, Topcu M, Amrom D, Andermann E, Dan B, Parrini E, Guerrini R, Scheffer IE, Berkovic SF, Leventer RJ, Shen Y, Wu BL,Barkovich AJ, Sahin M, Chang BS, Bamshad M, Nickerson DA, Shendure J, Poduri A,Yu TW, Walsh CA. Somatic mutations in cerebral cortical malformations. N Engl J Med. 2014 Aug 21;371(8):733-43. doi: 10.1056/NEJMoa1314432. PubMed PMID: 25140959

Das PP, Shao Z, Beyaz S, Apostolou E, Pinello L, De Los Angeles A, O'Brien K, Atsma JM, Fujiwara Y, Nguyen M, Ljuboja D, Guo G, Woo A, Yuan GC, Onder T, Daley  G, Hochedlinger K, Kim J, Orkin SH. Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity. Mol Cell. 2014 Jan 9;53(1):32-48. doi: 10.1016/j.molcel.2013.11.011. Epub 2013 Dec 19.PubMed PMID: 24361252; PubMed Central PMCID: PMC3919500.

Djordjevic, Darja. 2014. Accelerated Kigali. The Johannesburg Salon, Volume Seven. Gazit R, Mandal PK, Ebina W, Ben-Zvi A, Nombela-Arrieta C, Silberstein LE, Rossi DJ. Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J
Exp Med. 2014 Jun 23. pii: jem.20130428. [Epub ahead of print] PubMed PMID: 24958848.

Riddell J, Gazit R, Garrison BS, Guo G, Saadatpour A, Mandal PK, Ebina W, Volchkov P, Yuan GC, Orkin SH, Rossi DJ. Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. Cell. 2014 Apr 24;157(3):549-64. doi: 10.1016/j.cell.2014.04.006. PubMed PMID: 24766805; PubMed  Central PMCID: PMC4060823.

Sierra-Mercado D, Deckersbach T, Arulpragasam AR, Chou T, Rodman AM, Duffy A, McDonald EJ, Eckhardt CA, Corse AK, Kaur N, Eskandar EN, Dougherty DD. Decision making in avoidance-reward conflict: a paradigm for non-human primates and humans. Brain Struct Funct. 2014 Jun 27. [Epub ahead of print] PubMed PMID: 24969127.

Simon MV, Sheth SA, Eckhardt CA, Kilbride RD, Braver D, Williams Z, Curry W, Cahill D, Eskandar EN. Phase reversal technique decreases cortical stimulation time during motor mapping. J Clin Neurosci. 2014 Jun;21(6):1011-7. doi:
10.1016/j.jocn.2013.12.015. Epub 2014 Jan 29. PubMed PMID: 24679940.

Beyeler A, Eckhardt CA, Tye KM. Deciphering memory function with optogenetics. Prog Mol Biol Transl Sci. 2014;122:341-90. doi:10.1016/B978-0-12-420170-5.00012-X. PubMed PMID: 24484707.

Eshel N, Tian J. Dopamine gates sensory representations in cortex. J Neurophysiol. 2014 Jun 1;111(11):2161-3. doi: 10.1152/jn.00795.2013. Epub 2014 Jan 8. PMID: 24401705

Cai X, Evrony GD, Lehmann HS, Elhosary PC, Mehta BK, Poduri A, Walsh CA. Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain. Cell Rep. 2014 Sep 11;8(5):1280-9. doi:
10.1016/j.celrep.2014.07.043. Epub 2014 Aug 21. PubMed PMID: 25159146.

Bae BI, Tietjen I, Atabay KD, Evrony GD, Johnson MB, Asare E, Wang PP, Murayama AY, Im K, Lisgo SN, Overman L, Šestan N, Chang BS, Barkovich AJ, Grant PE, Topçu M, Politsky J, Okano H, Piao X, Walsh CA. Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning. Science. 2014 Feb 14;343(6172):764-8. doi: 10.1126/science.1244392. PubMed PMID: 24531968.

Reiff RE, Ali BR, Baron B, Yu TW, Ben-Salem S, Coulter ME, Schubert CR, Hill RS, Akawi NA, Al-Younes B, Kaya N, Evrony GD, Al-Saffar M, Felie JM, Partlow JN, Sunu CM, Schembri-Wismayer P, Alkuraya FS, Meyer BF, Walsh CA, Al-Gazali L,Mochida GH. METTL23, a transcriptional partner of GABPA, is essential for human cognition. Hum Mol Genet. 2014 Jul 1;23(13):3456-66. doi: 10.1093/hmg/ddu054. Epub 2014 Feb 5. PubMed PMID: 24501276; PubMed Central PMCID: PMC4049305.

Dreze M, Calkins AS, Gálicza J, Echelman DJ, Schnorenberg MR, Fell GL, Iwai S, Fisher DE, Szüts D, Iglehart JD, Lazaro JB. Monitoring Repair of UV-Induced 6-4-Photoproducts with a Purified DDB2 Protein Complex. PLoS One. 2014 Jan 28;9(1):e85896. doi: 10.1371/journal.pone.0085896. eCollection 2014. PMID: 24489677. PMCID: PMC3904869

Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. PMID: 24616378

van Teijlingen NH, Hölzemer A, Körner C, García-Beltrán WF, Schafer JL, Fadda L, Suscovich TJ, Brander C, Carrington M, Evans DT, van Baarle D, Altfeld M. Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03: 04 and modulate primary natural killer cell function. AIDS. 2014 Jun 19;28(10):1399-408. doi: 10.1097/QAD.0000000000000284. PubMed PMID: 24785948.

Bandopadhayay P, Bergthold G, Nguyen B, Schubert S, Gholamin S, Tang Y, Bolin S, Schumacher SE, Zeid R, Masoud S, Yu F, Vue N, Gibson WJ, Paolella BR, Mitra SS, Cheshier SH, Qi J, Liu KW, Wechsler-Reya R, Weiss WA, Swartling FJ, Kieran MW, Bradner JE, Beroukhim R, Cho YJ. BET bromodomain inhibition of MYC-amplified medulloblastoma. Clin Cancer Res. 2014 Feb 15;20(4):912-25. doi:10.1158/1078-0432.CCR-13-2281. Epub 2013 Dec 2. PubMed PMID: 24297863.

Gonzalez Castro LN, Hadjiosif AM, Hemphill MA, Smith MA. Environmental consistency determines the rate of motor adaptation. Curr Biol. 2014 May
19;24(10):1050-61. doi: 10.1016/j.cub.2014.03.049. Epub 2014 May 1. PubMed PMID: 24794296

Wu HG, Miyamoto YR, Gonzalez Castro LN, Ölveczky BP, Smith MA. Temporal structure of motor variability is dynamically regulated and predicts motor learning ability. Nat Neurosci. 2014 Feb;17(2):312-21. doi: 10.1038/nn.3616. Epub 2014 Jan 12. PubMed PMID: 24413700.

Vitti JJ, Grossman SR, Sabeti PC. Detecting natural selection in genomic data. Annu Rev Genet. 2013;47:97-120. doi: 10.1146/annurev-genet-111212-133526. Review. PubMed PMID: 24274750.

Engreitz JM, Sirokman K, McDonel P, Shishkin AA, Surka C, Russell P, Grossman SR, Chow AY, Guttman M, Lander ES. RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites. Cell. 2014 Sep 25;159(1):188-99. doi: 10.1016/j.cell.2014.08.018. PubMed PMID: 25259926; PubMed Central PMCID: PMC4177037.

Lewis CA, Parker SJ, Fiske BP, McCloskey D, Gui DY, Green CR, Vokes NI, Feist AM, Vander Heiden MG, Metallo CM. Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells. Mol Cell. 2014 May 28. pii: S1097-2765(14)00402-X. doi: 10.1016/j.molcel.2014.05.008. [Epub ahead of print] PubMed PMID: 24882210.

Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13. PubMed PMID: 24530296; PubMed Central PMCID: PMC4006117.

Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF. A genomic and evolutionary approach reveals non-genetic drug resistance in malaria. Genome
Biol. 2014 Nov 14;15(11):511. [Epub ahead of print] PubMed PMID: 25395010.

Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, Beroukhim R, Marto JA, Vidal M, Gaudet S, Hill DE, Livingston DM. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. Genes Dev. 2014 Sep 1;28(17):1957-75. doi: 10.1101/gad.241620.114. PubMed PMID: 25184681; PubMed Central PMCID: PMC4197947.

Hill SJ, Clark AP, Silver DP, Livingston DM. BRCA1 pathway function in basal-like breast cancer cells. Mol Cell Biol. 2014 Oct;34(20):3828-42. doi: 10.1128/MCB.01646-13. Epub 2014 Aug 4. PubMed PMID: 25092866; PubMed Central PMCID: PMC4187718.

Wagle N, Grabiner BC, Van Allen EM, Hodis E, Jacobus S, Supko JG, Stewart M, Choueiri TK, Gandhi L, Cleary JM, Elfiky AA, Taplin ME, Stack EC, Signoretti S, Loda M, Shapiro GI, Sabatini DM, Lander ES, Gabriel SB, Kantoff PW, Garraway LA, Rosenberg JE. Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib. Cancer Discov. 2014 May;4(5):546-53. doi: 10.1158/2159-8290.CD-13-0353. Epub 2014 Mar 13. PMID: 24625776

Giannakis M*, Hodis E*, Jasmine Mu X, Yamauchi M, Rosenbluh J, Cibulskis K, Saksena G, Lawrence MS, Qian ZR, Nishihara R, Van Allen EM, Hahn WC, Gabriel SB,  Lander ES, Getz G, Ogino S, Fuchs CS, Garraway LA. RNF43 is frequently mutated in colorectal and endometrial cancers. Nat Genet. 2014 Oct 26. doi: 10.1038/ng.3127. [Epub ahead of print] PubMed PMID: 25344691.

Cancer Genome Atlas Research Network (including E. Hodis). Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385. Epub 2014 Jul 9. Erratum in: Nature. 2014 Oct
9;514(7521):262. Rogers, K [corrected to Rodgers, K]. PubMed PMID: 25079552; PubMed Central PMCID: PMC4231481.

Wagle N, Van Allen EM, Treacy DJ, Frederick DT, Cooper ZA, Taylor-Weiner A, Rosenberg M, Goetz EM, Sullivan RJ, Farlow DN, Friedrich DC, Anderka K, Perrin D, Johannessen CM, McKenna A, Cibulskis K, Kryukov G, Hodis E, Lawrence DP, Fisher S, Getz G, Gabriel SB, Carter SL, Flaherty KT, Wargo JA, Garraway LA.  MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition. Cancer Discov. 2014 Jan;4(1):61-8. doi: 10.1158/2159-8290.CD-13-0631. Epub 2013 Nov 21. PMID: 24265154

Van Allen EM, Wagle N, Sucker A, Treacy DJ, Johannessen CM, Goetz EM, Place CS, Taylor-Weiner A, Whittaker S, Kryukov GV, Hodis E, Rosenberg M, McKenna A, Cibulskis K, Farlow D, Zimmer L, Hillen U, Gutzmer R, Goldinger SM, Ugurel S, Gogas HJ, Egberts F, Berking C, Trefzer U, Loquai C, Weide B, Hassel JC, Gabriel SB, Carter SL, Getz G, Garraway LA, Schadendorf D; Dermatologic Cooperative Oncology Group of Germany (DeCOG). The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma. Cancer Discov. 2014 Jan;4(1):94-109. doi: 10.1158/2159-8290.CD-13-0617. Epub 2013 Nov 21. PMID: 24265153

Hu WF, Chahrour MH, Walsh CA. The diverse genetic landscape of neurodevelopmental disorders. Annu Rev Genomics Hum Genet. 2014;15:195-213. doi: 10.1146/annurev-genom-090413-025600. PubMed PMID: 25184530.

Slowikowski K, Hu X, Raychaudhuri S. SNPsea: an algorithm to identify cell types, tissues, and pathways affected by risk loci. Bioinformatics. 2014 May 10. [Epub ahead of print] PubMed PMID: 24813542.

Hu X, Kim H, Raj T, Brennan PJ, Trynka G, Teslovich N, Slowikowski K, Chen WM, Onengut S, Baecher-Allan C, De Jager PL, Rich SS, Stranger BE, Brenner MB, Raychaudhuri S. Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4+ Effector Memory T Cells. PLoS Genet. 2014 Jun 26;10(6):e1004404. doi: 10.1371/journal.pgen.1004404. eCollection 2014 Jun. PubMed PMID: 24968232.

Shestov AA, Liu X, Ser Z, Cluntun AA, Hung YP, Huang L, Kim D, Le A, Yellen G, Albeck JG, Locasale JW. Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step. Elife. 2014 Jul 9;3. doi:
10.7554/eLife.03342. PubMed PMID: 25009227; PubMed Central PMCID: PMC4118620.

Hwong AR, Qaragholi N, Carpenter D, Joffe S, Campbell EG, Soleymani Lehmann L.A systematic review of state and manufacturer physician payment disclosure websites: implications for implementation of the Sunshine Act. J Law Med Ethics.
2014 Summer;42(2):208-19. doi: 10.1111/jlme.12136. PubMed PMID: 25040384.

Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Dev Cell. 2014 Feb 24;28(4):423-37. doi: 10.1016/j.devcel.2014.01.006. Epub 2014 Feb 13. PubMed PMID: 24530296; PubMed Central PMCID: PMC4006117.

Hwang WL*, Deindl S*, Harada BT, Zhuang X. Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA. Nature. 2014 Aug 14;512(7513):213-7. doi: 10.1038/nature13380. Epub 2014 Jun 29. PubMed PMID: 25043036; PubMed Central PMCID: PMC4134374

Knouse KA, Wu J, Whittaker CA, Amon A. Single cell sequencing reveals low levels of aneuploidy across mammalian tissues. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13409-14. doi: 10.1073/pnas.1415287111. Epub 2014 Sep 2. PubMed PMID:  25197050; PubMed Central PMCID: PMC4169915.

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