Upcoming Dissertation Defense Seminars

Shari Grossman 
Friday, October 19, 2018 at 2:00pm
Title: Predicting enhancer activity from DNA sequence

Broad Institute
Yellowstone Room
415 Main Street
Cambridge, MA 02142

Advisor: Eric Lander, D.Phil.
MIT Department of Biology

   

Recent Dissertation Defense Seminars

Seth Cassel 
Tuesday, September 11, 2018 at 10:00 am
Title: Interrogating the compositional and functional diversity of mSWI/SNF complexes

Harvard Medical School
New Research Building
Room 1031
77 Avenue Louis Pasteur
Boston, MA 02115

Advisor: Cigall Kadoch, Ph.D
Harvard Medical School Division of Medical Sciences - Biological and Biomedical Sciences

   

Omar O. Abudayyah
Tuesday, August 21, 2018 at 2:00pm
Title: Discovery of novel CRISPR enzymes for transcriptome engineering and human health

Broad Institute Auditorium
415 Main Street
Cambridge, MA 02142

Advisor: Feng Zhang, Ph.D.
MIT Department of Medical Engineering and Medical Physics

   

Mark Aurel Nagy 
Monday, July 30, 2018 at 1:00pm
Title: New insights into activity-dependent transcription in the brain

Harvard Medical School
Goldenson Building
Room 122
220 Longwood Avenue
Boston, MA  02115

Advisor: Michael Greenberg, Ph.D.
Harvard University (Division of Medical Sciences - Neuroscience)

   

Matthew Baum
Wednesday, June 20, 2018 at 10:00 am
Title: The Schizophrenia-Associated Gene, CSMD1, Encodes a Brain-Specific Complement Inhibitor

Harvard Medical School
Goldenson Building
Room 122
220 Longwood Avenue
Boston, MA  02115


Advisor: Beth Stevens, Ph.D.
Harvard University (Division of Medical Sciences - Neuroscience)

   

Amy Li

Friday, May 18, 2018 at 1:00pm
Title: Interrogation of regulatory T cell function and heterogeneity in a genetic mouse model of lung adenocarcinoma

Koch Institute Auditorium (76-156)
500 Main Street
Cambridge, MA 02139

Advisor: Tyler Jacks, Ph.D.
MIT Department of Biology

   

Kristen Mengwasser

Monday, May 14, 2018 at 10:00am
"Genetic Screening Approaches to Cancer Driver Characterization and Synthetic Lethal Target Discovery"

Harvard Medical School
New Research Building, Room 350
77 Avenue Louis Pasteur
Boston, MA  02115

Advisor: Stephen Elledge, Ph.D.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences)

   

Colin Fadzen

Friday, May 4, 2018 at 1:00pm
"Peptide-Mediated Delivery of Antisense Oligonucleotides and Chemotherapeutics Across Biological Barriers"

Massachusetts Institute of Technology
Building 4, Room 163
Cambridge, MA 02142

Advisor: Bradley Pentelute, Ph.D.
MIT Department of Chemistry

   

Emma Fink 
Friday, April 13, 2018 at 2:00 p.m.
"Investigating the Mechanism and Species-specificity of Thalomide Derivatives"

Harvard Institute of Medicine
Bray Room
4 Blackfan Circle
Boston, MA 02115

Advisor: Benjamin Ebert, M.D., D.Phil.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences)

   

Katherine van Schaik 
Monday, April 23, 2018, 12:00pm
"Medical Decision Making in Greco-Roman Antiquity"

Advisors: Mark Schiefsky, Ph.D., Christopher P. Jones, Ph.D., Frank Ruehli, M.D., Ph.D.
Harvard University (Department of Classics, Ancient History)

   

Sun Jin Lee 
Wednesday, March 21, 2018, (time TBA)
"Malaria in pregnancy: placental and trophoblast responses in placental malaria pathogenesis"


University of Cambridge, UK

Advisor: Stephen Charnock-Jones, Ph.D.
NIH OxCam-GPP

   

Eran Hodis
Monday, March 19, 2018 at 2:00p.m.
The Somatic Genetics of Human Melanoma”

Harvard Medical School
Building C, Cannon Room
240 Longwood Ave.
Boston, MA  02115

Advisor: Aviv Regev, Ph.D.
Harvard University (GSAS-Biophysics)

   

Yakir Reshef 
Friday, March 16, 2018 at 12:00 p.m.
“Detecting meaningful relationships in large data sets

Harvard University
Cruft Laboratory, Room 309
19A Oxford Street
Cambridge, MA 02138

Advisors: Ryan Adams, Ph.D. & Michael Mitzenmacher, Ph.D.
Harvard University (GSAS – SEAS - Computer Sciences)

   

Nicholas Bodnar 
Monday, March 5, 2018 at 2:00 p.m.
“Mechanism and structure of the Cdc48 ATPase complex”

Harvard Medical School
Building C, Cannon Room
240 Longwood Ave.
Boston, MA  02115

Advisor: Tom Rapoport, Ph.D.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences)

   

Rachel Rodin 
Tuesday, March 6, 2018 at 12:00p.m.
"The Human Brain as a Mosaic: Somatic Mutation in Autism Spectrum Disorder, Aging, and Neurodegeneration"

Harvard Medical School 
Goldenson 122
220 Longwood Avenue
Boston, MA 02115

Advisor: Chris A. Walsh, M.D., Ph.D.
Harvard University (Division of Medical Sciences - Neuroscience)

   

David Cox

Tuesday, March 6, 2018 at 2:00pm
Characterization and application of type VI-B RNA-targeting CRISPR systems”

Broad Institute
Olympus Room
415 Main Street
Cambridge, MA  02142

Advisor: Feng Zhang, Ph.D.
MIT Division of HST (Biology)

   

Clara Starkweather 
Monday, March 12, 2018 at 1:30p.m.
Hidden State Inference in the Midbrain Dopamine System”

Harvard University
Biolabs, Room 1080
16 Divinity Avenue
Cambridge, MA 02138

Advisor: Naoshige Uchida, Ph.D.
Harvard University (Division of Medical Sciences - Neuroscience)

   

Daniel Pearson 
Thursday, March 1, 2018 at 12:45 p.m.
"Novel Roles for the Terminal RNA Uridylyltransferases ZCCHC6 and ZCCHC11 in Development and Disease"

Harvard Medical School
Tosteson Medical Education Center
Room 227
260 Longwood Avenue
Boston, MA 02115

Advisor: George Daley, M.D., Ph.D.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences)

   

Edward Li 
Thursday, February 8, 2018 at 9:00 a.m.
“Investigating the roles of IRF6 in epithelial maturation, craniofacial development, and orofacial cleft pathogenesis”

Massachusetts General Hospital
Haber Auditorium
55 Fruit Street
Boston, MA 02114

Advisor: Eric Liao, M.D., Ph.D.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences)

   

Sana Raoof 
Monday, January 8, 2018 at 12:15 p.m.
Targeting FGFR to overcome EMT-related resistance to EGFR inhibition in EGFR-mutated Non-small Cell Lung Cancer

Harvard Medical School
Gordon Hall
Waterhouse Faculty Room (Rm. 106)
25 Shattuck Street
Boston, MA 02115

Advisors: Dan Haber, M.D., Ph.D. & Aaron Hata, M.D., Ph.D.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences)

   

Jamaji Nwanaji-Enwerem
Monday, November 20, 2017 at 9:00a.m.
“On Aging: Analyses of Long-term Fine Particulate Air Pollution Exposure, Genetic Variants, and Blood DNA Methylation Age in the Elderly”

Harvard T.H. Chan School of Public Health
Kresge G3
677 Huntington Ave.
Boston, MA 02115

Advisors: Marc Weisskopf, Ph.D. & Andrea Baccarelli, M.D., Ph.D.
Harvard University (Biological Sciences in Public Health) 

   

Dustin Griesemer
Friday, June 9, 2017 at 12:00p.m.
Assaying 3-Prime Untranslated Region Variants in a Massively Parallel Fashion

Broad Institute
Monadnock Room (Rm. 2040)
415 Main Street
Cambridge, MA  02142

Advisors: Pardis Sabeti, M.D., D.Phil. & Carl Novina, M.D., Ph.D.
Harvard University (Division of Medical Sciences - Bioinformatics and Integrative Genomics) 

   

Quinlan Sievers
Friday, May 19, 2017 at 10:00a.m.
Thalidomide analogs induce targeting of C2H2 zinc finger degrons by the CRL4CRBN E3 ubiquitin ligase

The Broad Institute
7 Cambridge Center
Main Auditorium
Cambridge, MA 02142

Advisor: Benjamin Ebert, M.D., D.Phil.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences) 

   

Ershela Durresi 
Monday, May 22, 2017 at 3:00p.m.
Genome-wide identification and analysis of human neuronal activity-dependent enhancers in evolution and disease

Harvard Medical School
Goldenson 122
220 Longwood Avenue
Boston, MA 02115


Advisor: Michael Greenberg, Ph.D.
Harvard University (Division of Medical Sciences - Neuroscience) 

   

Dayan (Jack) Li 
Monday, May 15, 2017 at 1:00 p.m.
Establishment and Maintenance of Pattern at the Ends of the Planarian Anterior-Posterior Axis

McGovern Auditorium (1st Floor)
Whitehead Institute for Biomedical Research
9 Cambridge Center
Cambridge, MA 02142

Advisor: Peter Reddien, Ph.D.
MIT Division of HST (Biology)

   

Dan Gui
Monday, May 8, 2017 at 3:00p.m.
The Role of Respiration in Supporting Cell Proliferation

Massachusetts Institute of Technology
Building 68, Room 181
Cambridge, MA 02142

Advisor: Matthew Vander Heiden, M.D., Ph.D.
MIT Division of HST (Biology)

   

David Reshef
Thursday, May 4, 2017 at 10:00a.m.
Equitability and Dependence: Detecting Novel Associations in Large Data Sets”

MIT Computer Science and Artificial Intelligence Laboratory
The Stata Center
Room 32-G449 (Kiva)
32 Vassar Street
Cambridge, MA 02139

Advisors: Tommi Jaakkola, Ph.D. & Joshua Tenenbaum, Ph.D.
MIT (Electrical Engineering and Computer Science)

   

Benjamin Steinhorn
Thursday, May 4, 2017 at 3:00p.m.
Targeted measurement and manipulation of hydrogen peroxide in the cardiovascular system

Harvard Medical School
Building C, Cannon Room
240 Longwood Ave.
Boston, MA  02115


Advisor: Thomas Michel, M.D., Ph.D.
Harvard University (GSAS-Biophysics)

   

Neil Blok
Thursday, March 17, 2017 at 3:00p.m.
Structural and functional studies of peroxisome matrix protein import

Harvard Medical School
Goldenson 122
220 Longwood Avenue
Boston, MA 02115


Advisor: Tom A. Rapoport, Ph.D.
Harvard University (Division of Medical Sciences - Biological and Biomedical Sciences) 

   

Vipul Kumar

Monday, April 10, 2017 at 3:00p.m.
Elucidating Classical and Alternative Pathways of Non-Homologous End-Joining in B-Lymphocytes

Harvard Medical School
Tosteson Medical Education Center
Room 250
260 Longwood Avenue
Boston, MA 02115

Advisor: Frederick W. Alt, Ph.D.
Harvard University (Division of Medical Sciences-Biological and Biomedical Sciences)

   

Vincentius Jeremy Suhardi
Wednesday, March 29, 2017 at 9:30 a.m.
“Drug Eluting Prosthetic Joints through Drug Cluster Morphology Control”

MIT E25-117
45 Carleton Street
Cambridge, MA 02142

Advisor: Ebru Oral, Ph.D.
MD-PhD Candidate in HST MEMP

   

Joyce Hwang

Monday, March 27, 2017 at 2:00p.m.
Elucidating influences of substrate DNA sequences on AID targeting and outcome during antibody maturation”

Boston Children's Hospital
Karp Family Research Building
9th Floor
1 Blackfan Circle
Boston, MA  02115

Advisor: Frederick Alt, Ph.D.
Harvard University (Division of Medical Sciences - Committee on Immunology)

   

Jeremiah Wala

Monday, March 6, 2017 at 11:00a.m.
Genome-wide detection of structural variants and signatures of their selection in cancer

Broad Institute
75 Ames Street
Yellowstone, Room 2001
Cambridge, MA 02142

Advisor: Rameen Beroukhim, M.D., Ph.D.
Harvard University (Division of Medical Sciences-Biological and Biomedical Sciences)

   

Rachel Wolfson

Tuesday, February 28, 2017 at 2:00p.m.
Understanding the nutrient sensing branch upstream of mTORC1”

Whitehead Institute Auditorium
455 Main Street
Cambridge, MA 02142

Advisor: David Sabatini, M.D., Ph.D.
MIT Division of HST (Biology)

   

Winston Yan

Wednesday, February 1, 2017 at 1:00p.m.
Towards therapeutic applications of CRISPR-Cas nucleases: developing technologies for in vivo gene editing & evaluating genome-wide specificity

The Monadnock Room
2nd Floor, Broad Institute
415 Main Street
Cambridge, MA 02142


Advisor: Feng Zhang, Ph.D.
Harvard University (GSAS-Biophysics)

   

William Lo

Wednesday, December 21, 2016 at 9:00a.m.
Microscopic Image Guidance: Real-time Thermal Therapy Monitoring for Epithelial Lesions

Harvard Medical School
Building C, Cannon Room
240 Longwood Ave.
Boston, MA  02115

Advisors: Brett E. Bouma, Ph.D. & Benjamin J. Vakoc, Ph.D.
MD-PhD Candidate in HST MEMP - Biophysics