Student Publications

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2014


Lee DH, Acharya SS, Kwon M, Drane P, Guan Y, Adelmant G, Kalev P, Shah J, Pellman D, Marto JA, Chowdhury D. Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks. Mol Cell. 2014 May 8;54(3):512-25. doi: 10.1016/j.molcel.2014.03.020. Epub 2014 Apr 3. PMID: 24703952 PMCID: PMC4030556


Amamoto, R., Arlotta, P. Development-Inspired Reprogramming of the Central Nervous System. Science. In preparation. Science. 2014 Jan 31;343(6170):1239882. doi: 10.1126/science.1239882. PMID: 24482482


Ben-Zvi A, Lacoste B, Kur E, Andreone BJ, Mayshar Y, Yan H, Gu C. Mfsd2a is critical for the formation and function of the blood-brain barrier. Nature. 2014 May 22;509(7501):507-11. doi: 10.1038/nature13324. Epub 2014 May 14. PMID: 24828040


Das PP, Shao Z, Beyaz S, Apostolou E, Pinello Angeles Ade L, O'Brien K, Atsma JM, Fujiwara Y, Nguyen M, Ljuboja D, Guo G, Woo A, Yuan GC, Onder T, Daley G, Hochedlinger K, Kim J, Orkin SH. Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity. Mol Cell. 2014 Jan 9;53(1):32-48. doi: 10.1016/j.molcel.2013.11.011. Epub 2013 Dec 19. PMID: 24361252 PMCID: PMC3919500


Haspot F, Li HW, Lucas CL, Fehr T, Beyaz S, Sykes M. Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells. Am J Transplant. 2014 Jan;14(1):49-58. doi: 10.1111/ajt.12525. Epub 2013 Dec 4. PMID: 24304495 PMCID: PMC4045013


Bonham KS, Kagan JC. Endosomes as Platforms for NOD-like Receptor Signaling. Cell Host Microbe. 2014 May 14;15(5):523-5. doi: 10.1016/j.chom.2014.05.001. PMID: 24832447


Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC. A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 2014 Feb 13;156(4):705-16. doi: 10.1016/j.cell.2014.01.019. PMID: 24529375 PMCID: PMC3951743


Nunes-Alves C, Booty MG, Carpenter SM, Jayaraman P, Rothchild AC, Behar SM. In search of a new paradigm for protective immunity to TB. Nat Rev Microbiol. 2014 Apr;12(4):289-99. doi: 10.1038/nrmicro3230. Epub 2014 Mar 3. PMID: 24590243


Choi Y, Mango SE. Hunting for Darwin's gemmules and Lamarck's fluid: Transgenerational signaling and histone methylation. Biochim Biophys Acta. 2014 May 21. pii: S1874-9399(14)00117-5. doi: 10.1016/j.bbagrm.2014.05.011. [Epub ahead of print] PMID: 24859459


Chu Y, Fioravante D, Leitges M, Regehr WG. Calcium-Dependent PKC Isoforms Have Specialized Roles in Short-Term Synaptic Plasticity. Neuron. 2014 May 21;82(4):859-71. doi: 10.1016/j.neuron.2014.04.003. Epub 2014 May 1. PMID: 24794094


Park SM, Deering RP, Lu Y, Tivnan P, Lianoglou S, Al-Shahrour F, Ebert BL, Hacohen N, Leslie C, Daley GQ, Lengner CJ, Kharas MG. Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs. J Exp Med. 2014 Jan 13;211(1):71-87. doi: 10.1084/jem.20130736. Epub 2014 Jan 6. PMID: 24395885 PMCID: PMC3892968


Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, Dobbins J, Gagnon E, Thomas PG, Wucherpfennig KW, Vignali DA. Membrane Association of the CD3ε Signaling Domain Is Required for Optimal T Cell Development and Function. J Immunol. 2014 Jul 1;193(1):258-67. doi: 10.4049/jimmunol.1400322. Epub 2014 Jun 4. PMID: 24899501 PMCID: PMC4065803


Birnbaum ME, Mendoza JL, Sethi DK, Dong S, Glanville J, Dobbins J, Ozkan E, Davis MM, Wucherpfennig KW, Garcia KC. Deconstructing the peptide-MHC specificity of T cell recognition. Cell. 2014 May 22;157(5):1073-87. doi: 10.1016/j.cell.2014.03.047. PMID: 24855945 PMCID: PMC4071348


Donahue RJ, Muschamp JW, Russo SJ, Nestler EJ, Carlezon WA Jr. Effects of Striatal ΔFosB Overexpression and Ketamine on Social Defeat Stress-Induced Anhedonia in Mice. Biol Psychiatry. 2014 Jan 8. pii: S0006-3223(14)00004-3. doi: 10.1016/j.biopsych.2013.12.014. [Epub ahead of print] PMID: 24495460


Dwyer DF, Woodruff MC, Carroll MC, Austen KF, Gurish MF. B Cells Regulate CD4+ T Cell Responses to Papain following B Cell Receptor-Independent Papain Uptake. J Immunol. 2014 Jun 13. pii: 1303247. [Epub ahead of print] PMID: 24928991


Eshel N, Tian J. Dopamine gates sensory representations in cortex. J Neurophysiol. 2014 Jun 1;111(11):2161-3. doi: 10.1152/jn.00795.2013. Epub 2014 Jan 8. PMID: 24401705


Fisek M, Wilson RI. Stereotyped connectivity and computations in higher-order olfactory neurons. Nat Neurosci. 2014 Feb;17(2):280-8. doi: 10.1038/nn.3613. Epub 2013 Dec 22. PMID: 24362761 PMCID: PMC3992254


Luo L, Cook N, Venkatachalam V, Martinez-Velazquez LA, Zhang X, Calvo AC, Hawk J, MacInnis BL, Frank M, Ng JH, Klein M, Gershow M, Hammarlund M, Goodman MB, Colón-Ramos DA, Zhang Y, Samuel AD. Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2776-81. doi: 10.1073/pnas.1315205111. Epub 2014 Feb 3. PMID: 24550307 PMCID: PMC3932917


van Teijlingen NH, Hölzemer A, Körner C, García-Beltrán WF, Schafer JL, Fadda L, Suscovich TJ, Brander C, Carrington M, Evans DT, van Baarle D, Altfeld M. Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03: 04 and modulate primary natural killer cell function. AIDS. 2014 Jun 19;28(10):1399-408. doi: 10.1097/QAD.0000000000000284. PMID: 24785948


Grayson AR, Walsh EM, Cameron MJ, Godec J, Ashworth T, Ambrose JM, Aserlind AB, Wang H, Evan GI, Kluk MJ, Bradner JE, Aster JC, French CA. MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma. Oncogene. 2014 Mar 27;33(13):1736-42. doi: 10.1038/onc.2013.126. Epub 2013 Apr 22. PMID: 23604113 PMCID: PMC3942361 read article


Kurachi M, Barnitz RA, Yosef N, Odorizzi PM, DiIorio MA, Lemieux ME, Yates K, Godec J, Klatt MG, Regev A, Wherry EJ, Haining WN. The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells. Nat Immunol. 2014 Apr;15(4):373-83. doi: 10.1038/ni.2834. Epub 2014 Mar 2. PMID: 24584090 PMCID: PMC4000237


Wang Y, Godec J, Ben-Aissa K, Cui K, Zhao K, Pucsek AB, Lee YK, Weaver CT, Yagi R, Lazarevic V. The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells. Immunity. 2014 Mar 20;40(3):355-66. doi: 10.1016/j.immuni.2014.01.002. Epub 2014 Feb 13. PMID: 24530058 PMCID: PMC3965587


Goodman BS, Reck-Peterson SL. Engineering defined motor ensembles with DNA origami. Methods Enzymol. 2014;540:169-88. doi: 10.1016/B978-0-12-397924-7.00010-8. PMID: 4630107


Gornstein E, Schwarz TL. The paradox of paclitaxel neurotoxicity: Mechanisms and unanswered questions. Neuropharmacology. 2014 Jan;76 Pt A:175-83. doi: 10.1016/j.neuropharm.2013.08.016. Epub 2013 Aug 24. PMID: 23978385


Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, Jiang L, Yin J, Ye L, Su DF, Yang J, Xie G, Keystone E, Westra HJ, Esko T, Metspalu A, Zhou X, Gupta N, Mirel D, Stahl EA, Diogo D, Cui J, Liao K, Guo MH, Myouzen K, Kawaguchi T, Coenen MJ, van Riel PL, van de Laar MA, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Bridges SL Jr, Zhernakova A, Toes RE, Tak PP, Miceli-Richard C, Bang SY, Lee HS, Martin J, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Rantapää-Dahlqvist S, Arlestig L, Choi HK, Kamatani Y, Galan P, Lathrop M; RACI consortium; GARNET consortium, Eyre S, Bowes J, Barton A, de Vries N, Moreland LW, Criswell LA, Karlson EW, Taniguchi A, Yamada R, Kubo M, Liu JS, Bae SC, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Raychaudhuri S, Stranger BE, De Jager PL, Franke L, Visscher PM, Brown MA, Yamanaka H, Mimori T, Takahashi A, Xu H, Behrens TW, Siminovitch KA, Momohara S, Matsuda F, Yamamoto K, Plenge RM. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 2014 Feb 20;506(7488):376-81. doi: 10.1038/nature12873. Epub 2013 Dec 25. PMID: 24390342 PMCID: PMC3944098


Guth CA, Sodroski J. Contribution of PDZD8 to stabilization of the human immunodeficiency virus type 1 capsid. J Virol. 2014 May;88(9):4612-23. doi: 10.1128/JVI.02945-13. Epub 2014 Feb 19. PMID: 24554657 PMCID: PMC3993830


Ho BT, Dong TG, Mekalanos JJ. A view to a kill: the bacterial type VI secretion system. Cell Host Microbe. 2014 Jan 15;15(1):9-21. doi: 10.1016/j.chom.2013.11.008. Epub 2013 Dec 11. PMID: 24332978 PMCID: PMC3936019


Bröcker MJ, Ho JM, Church GM, Söll D, O'Donoghue P. Recoding the genetic code with selenocysteine. Angew Chem Int Ed Engl. 2014 Jan 3;53(1):319-23. doi: 10.1002/anie.201308584. PMID: 24511637


Colak S, Zimberlin CD, Fessler E, Hogdal L, Prasetyanti PR, Grandela CM, Letai A, Medema JP. Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells. Cell Death Differ. 2014 Mar 28. doi: 10.1038/cdd.2014.37. [Epub ahead of print] PMID: 24682005


Huynh A, Zhang R, Turka LA. Signals and pathways controlling regulatory T cells. Immunol Rev. 2014 Mar;258(1):117-31. doi: 10.1111/imr.12148. PMID: 24517429


Yang L, Mali P, Kim-Kiselak C, Church G. CRISPR-Cas-Mediated Targeted Genome Editing in Human Cells. Methods Mol Biol. 2014;1114:245-67. doi: 10.1007/978-1-62703-761-7_16. PMID: 24557908


Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, Kajimura S, Piston DW, Mathis D, Cinti S, Shulman GI, Seale P, Spiegelman BM. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021. PMID: 24439384 PMCID: PMC3922400


Holt JR, Pan B, Koussa MA, Asai Y. TMC function in hair cell transduction. Hear Res. 2014 Jan 11. pii: S0378-5955(14)00002-1. doi: 10.1016/j.heares.2014.01.001. [Epub ahead of print] PMID: 24423408


Koussa MA, Sotomayor M, Wong WP. Protocol for sortase-mediated construction of DNA-protein hybrids and functional nanostructures. Methods. 2014 May 15;67(2):134-41. doi: 10.1016/j.ymeth.2014.02.020. Epub 2014 Feb 22. PMID: 24568941


Shouval DS, Biswas A, Goettel JA, McCann K, Conaway E, Redhu NS, Mascanfroni ID, Al Adham Z, Lavoie S, Ibourk M, Nguyen DD, Samsom JN, Escher JC, Somech R, Weiss B, Beier R, Conklin LS, Ebens CL, Santos FG, Ferreira AR, Sherlock M, Bhan AK, Müller W, Mora JR, Quintana FJ, Klein C, Muise AM, Horwitz BH, Snapper SB.Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function. Immunity. 2014 May 15;40(5):706-19. doi: 10.1016/j.immuni.2014.03.011. Epub 2014 May 1. PMID: 24792912


Lee D, Boscolo E, Durham JT, Mulliken JB, Herman IM, Bischoff J. Propranolol Targets Contractility of Infantile Hemangioma-derived Pericytes. Br J Dermatol. 2014 Apr 10. doi: 10.1111/bjd.13048. [Epub ahead of print] PMID: 24720697


Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler D, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N . Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science. 2014 Mar 7;343(6175):1246980. doi: 10.1126/science.1246980. PMID: 24604203


Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science. 2014 May 2;344(6183):519-523. doi: 10.1126/science.1249547. PMID: 24786080


Gu Z, Liu F, Tonkova EA, Lee SY, Tschumperlin DJ, Brenner MB. Soft matrix is a natural stimulator for cellular invasiveness. Mol Biol Cell. 2014 Feb;25(4):457-69. doi: 10.1091/mbc.E13-05-0260. Epub 2013 Dec 11. PMID: 24336521 PMCID: PMC3923638 read article


Lee Y, Collins M, Kuchroo VK. Unexpected targets and triggers of autoimmunity. J Clin Immunol. 2014 Jul;34 Suppl 1:56-60. doi: 10.1007/s10875-014-0040-5. Epub 2014 May 1. PMID: 24789684


David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, Ling AV, Devlin AS, Varma Y, Fischbach MA, Biddinger SB, Dutton RJ, Turnbaugh PJ. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014 Jan 23;505(7484):559-63. doi: 10.1038/nature12820. Epub 2013 Dec 11. PMID: 24336217 PMCID: PMC3957428


Louros SR, Hooks BM, Litvina L, Carvalho AL, Chen C. A role for stargazin in experience-dependent plasticity. Cell Rep. 2014 Jun 12;7(5):1614-25. doi: 10.1016/j.celrep.2014.04.054. Epub 2014 May 29. PMID: 24882000


Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA. Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discov. 2014 Apr;4(4):452-65. doi: 10.1158/2159-8290.CD-13-0646. Epub 2014 Jan 20. PMID: 24444711 PMCID: PMC3980023


Chung AW, Ghebremichael M, Robinson H, Brown E, Choi I, Lane S, Dugast AS, Schoen MK, Rolland M, Suscovich TJ, Mahan AE, Liao L, Streeck H, Andrews C, Rerks-Ngarm S, Nitayaphan S, de Souza MS, Kaewkungwal J, Pitisuttithum P, Francis D, Michael NL, Kim JH, Bailey-Kellogg C, Ackerman ME, Alter G. Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines. Sci Transl Med. 2014 Mar 19;6(228):228ra38. doi: 10.1126/scitranslmed.3007736. PMID: 24648341


Savchenko AS, Borissoff JI, Martinod K, De Meyer SF, Gallant M, Erpenbeck L, Brill A, Wang Y, Wagner DD. VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice. Blood. 2014 Jan 2;123(1):141-8. doi: 10.1182/blood-2013-07-514992. Epub 2013 Nov 7. PMID: 24200682 PMCID: PMC3879903


Thomas MP, Whangbo J, McCrossan G, Deutsch AJ, Martinod K, Walch M, Lieberman J. Leukocyte protease binding to nucleic acids promotes nuclear localization and cleavage of nucleic Acid binding proteins. J Immunol. 2014 Jun 1;192(11):5390-7. doi: 10.4049/jimmunol.1303296. Epub 2014 Apr 25. PMID:24771851 PMCID: PMC4041364


McCarthy KR, Johnson WE. Plastic proteins and monkey blocks: how lentiviruses evolved to replicate in the presence of primate restriction factors. PLoS Pathog. 2014 Apr 17;10(4):e1004017. doi: 10.1371/journal.ppat.1004017. eCollection 2014. PMID: 24743473 PMCID: PMC3990706 read article


Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. PMID: 24616378


Nizza ST, Campbell JJ. CD11b+ migratory dendritic cells mediate CD8 T cell cross-priming and cutaneous imprinting after topical immunization. PLoS One. 2014 Mar 11;9(3):e91054. doi: 10.1371/journal.pone.0091054. eCollection 2014. PMID: 24618819 PMCID: PMC3949685 read article


Cheng L, Desai J, Miranda CJ, Duncan JS, Qiu W, Nugent AA, Kolpak AL, Wu CC, Drokhlyansky E, Delisle MM, Chan WM, Wei Y, Propst F, Reck-Peterson SL, Fritzsch B, Engle EC. Human CFEOM1 Mutations Attenuate KIF21A Autoinhibition and Cause Oculomotor Axon Stalling. Neuron. 2014 Mar 18. pii: S0896-6273(14)00169-X. doi: 10.1016/j.neuron.2014.02.038. [Epub ahead of print] PMID: 24656932


Pisanello F, Sileo L, Oldenburg IA, Pisanello M, Martiradonna L, Assad JA, Sabatini BL, De Vittorio M. Multipoint-Emitting Optical Fibers for Spatially Addressable In Vivo Optogenetics. Neuron. 2014 May 29. pii: S0896-6273(14)00356-0. doi: 10.1016/j.neuron.2014.04.041. [Epub ahead of print] PMID: 24881834


Davila SJ, Olive AJ, Starnbach MN. Integrin α4β1 is necessary for CD4+ T cell-mediated protection against genital Chlamydia trachomatis infection. J Immunol. 2014 May 1;192(9):4284-93. doi: 10.4049/jimmunol.1303238. Epub 2014 Mar 21. PMID: 24659687 PMCID: PMC3995848


Olive AJ, Haff MG, Emanuele MJ, Sack LM, Barker JR, Elledge SJ, Starnbach MN. Chlamydia trachomatis-induced alterations in the host cell proteome are required for intracellular growth. Cell Host Microbe. 2014 Jan 15;15(1):113-24. doi: 10.1016/j.chom.2013.12.009. PMID: 24439903 PMCID: PMC3932326


Riol-Blanco L, Ordovas-Montanes J, Perro M, Naval E, Thiriot A, Alvarez D, Paust S, Wood JN, von Andrian UH. Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation. Nature. 2014 Jun 5;510(7503):157-61. doi: 10.1038/nature13199. Epub 2014 Apr 23. PMID: 24759321


Järås M, Miller PG, Chu LP, Puram RV, Fink EC, Schneider RK, Al-Shahrour F, Peña P, Breyfogle LJ, Hartwell KA, McConkey ME, Cowley GS, Root DE, Kharas MG, Mullally A, Ebert BL. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J Exp Med. 2014 Apr 7;211(4):605-12. doi: 10.1084/jem.20131033. Epub 2014 Mar 10. PMID: 24616378 PMCID: PMC3978274


Raiser DM, Narla A, Ebert BL. The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders. Leuk Lymphoma. 2014 Mar;55(3):491-500. doi: 10.3109/10428194.2013.812786. Epub 2013 Aug 28. PMID: 23863123


Brenneis C, Kistner K, Puopolo M, Jo S, Roberson D, Sisignano M, Segal D, Cobos EJ, Wainger BJ, Labocha S, Ferreirós N, von Hehn C, Tran J, Geisslinger G, Reeh PW, Bean BP, Woolf CJ. Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block. Br J Pharmacol. 2014 Jan;171(2):438-51. doi: 10.1111/bph.12466. PMID: 24117225 PMCID: PMC3904263


Batal I, Azzi J, Mounayar M, Abdoli R, Moore R, Lee JY, Rosetti F, Wang C, Fiorina P, Sackstein R, Ichimura T, Abdi R. The mechanisms of up-regulation of dendritic cell activity by oxidative stress. J Leukoc Biol. 2014 Mar 27. [Epub ahead of print] PMID: 24676276


Rothchild AC, Jayaraman P, Nunes-Alves C, Behar SM. iNKT cell production of GM-CSF controls Mycobacterium tuberculosis. PLoS Pathog. 2014 Jan;10(1):e1003805. doi: 10.1371/journal.ppat.1003805. Epub 2014 Jan 2. PMID: 24391492 PMCID: PMC3879349 read article


Sadegh C, Macklis JD. Established monolayer differentiation of mouse embryonic stem cells generates heterogeneous neocortical-like neurons stalled at a stage equivalent to midcorticogenesis. J Comp Neurol. 2014 Mar 8. doi: 10.1002/cne.23576. [Epub ahead of print] PMID: 24610556


Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, Xia J, Tan TG, Sefik E, Yajnik V, Sharpe AH, Quintana FJ, Mathis D, Benoist C, Hafler DA, Kuchroo VK. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity. 2014 Apr 17;40(4):569-81. doi: 10.1016/j.immuni.2014.02.012. PMID: 24745333


Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D. Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6696-701. doi: 10.1073/pnas.1405634111. Epub 2014 Apr 21. PMID: 24753589 PMCID: PMC4020091


Brooks AN, Choi PS, de Waal L, Sharifnia T, Imielinski M, Saksena G, Pedamallu CS, Sivachenko A, Rosenberg M, Chmielecki J, Lawrence MS, DeLuca DS, Getz G, Meyerson M. A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events. PLoS One. 2014 Jan 31;9(1):e87361. doi: 10.1371/journal.pone.0087361. eCollection 2014. PMID: 24498085 PMCID: PMC3909098 read article


Tata A, Stoppel DC, Hong S, Ben-Zvi A, Xie T, Gu C. An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling. J Cell Biol. 2014 May 26;205(4):573-590. Epub 2014 May 19. PMID: 24841563


Krashes MJ, Shah BP, Madara JC, Olson DP, Strochlic DE, Garfield AS, Vong L, Pei H, Watabe-Uchida M, Uchida N, Liberles SD, Lowell BB. An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger. Nature. 2014 Mar 13;507(7491):238-42. doi: 10.1038/nature12956. Epub 2014 Feb 2. PMID: 24487620 PMCID: PMC3955843


Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, Xia J, Tan TG, Sefik E, Yajnik V, Sharpe AH, Quintana FJ, Mathis D, Benoist C, Hafler DA, Kuchroo VK. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity. 2014 Apr 17;40(4):569-81. doi: 10.1016/j.immuni.2014.02.012. PMID: 24745333


Eshel N, Tian J. Dopamine gates sensory representations in cortex. J Neurophysiol. 2014 Jun 1;111(11):2161-3. doi: 10.1152/jn.00795.2013. Epub 2014 Jan 8. PMID: 24401705


Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME. Npas4 Regulates Excitatory-Inhibitory Balance within Neural Circuits through Cell-Type-Specific Gene Programs. Cell. 2014 May 22;157(5):1216-29. doi: 10.1016/j.cell.2014.03.058. PMID: 24855953


Berger AH, Imielinski M, Duke F, Wala J, Kaplan N, Shi GX, Andres DA, Meyerson M. Oncogenic RIT1 mutations in lung adenocarcinoma. Oncogene. 2014 Jan 27. doi: 10.1038/onc.2013.581. [Epub ahead of print] PMID: 24469055


Wu Z, Autry AE, Bergan JF, Watabe-Uchida M, Dulac CG. Galanin neurons in the medial preoptic area govern parental behaviour. Nature. 2014 May 15;509(7500):325-30. doi: 10.1038/nature13307. PMID: 24828191


Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D. Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission. J Virol. 2014 May;88(9):5014-28. doi: 10.1128/JVI.02785-13. Epub 2014 Feb 19. PMID: 24554659 PMCID: PMC3993815


Yuen GJ, Ausubel FM. Enterococcus infection biology: lessons from invertebrate host models. J Microbiol. 2014 Mar;52(3):200-10. doi: 10.1007/s12275-014-4011-6. Epub 2014 Mar 1. PMID: 24585051


Tan X, Fuchs BB, Wang Y, Chen W, J Yuen G, Chen RB, Jayamani E, Anastassopoulou C, Pukkila-Worley R, Coleman JJ, Mylonakis E. The Role of Candida albicans SPT20 in Filamentation, Biofilm Formation and Pathogenesis. PLoS One. 2014 Apr 14;9(4):e94468. doi: 10.1371/journal.pone.0094468. eCollection 2014. PMID: 24732310 PMCID: PMC3986095 read article


top

2013


Chatterjee P, Agyemang AF, Alimzhanov MB, Degn S, Tsiftsoglou SA, Alicot E, Jones SA, Ma M, Carroll MC. Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner. Eur J Immunol. 2013 Jun 10. doi: 10.1002/eji.201343412. [Epub ahead of print] PMID: 23749435


Albacker LA, Chaudhary V, Chang YJ, Kim HY, Chuang YT, Pichavant M, DeKruyff RH, Savage PB, Umetsu DT. Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity. Nat Med. 2013 Oct;19(10):1297-304. doi: 10.1038/nm.3321. Epub 2013 Sep 1. PMID: 23995283


Albacker LA, Yu S, Bedoret D, Lee WL, Umetsu SE, Monahan S, Freeman GJ, Umetsu DT, DeKruyff RH. TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells. Mucosal Immunol. 2013 May;6(3):580-90. doi: 10.1038/mi.2012.100. Epub 2012 Nov 14. PMID: 23149665


Chaudhary V, Albacker LA, Deng S, Chuang YT, Li Y, Umetsu DT, Savage PB. Synthesis of fungal glycolipid asperamide B and investigation of its ability to stimulate natural killer T cells. Org Lett. 2013 Oct 18;15(20):5242-5. doi: 10.1021/ol4024375. Epub 2013 Oct 10. PMID: 24111801


Amamoto, R., Arlotta, P. Reshaping the Brain: Direct Lineage Conversion in the Nervous System. F1000Prime Rep. 2013 Sep 2;5:33. eCollection 2013. PMID: 24049637 PMCID: PMC3768326 read article


Su X, Arellano-Santoyo H, Portran D, Gaillard J, Vantard M, Thery M, Pellman D. Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control. Nat Cell Biol. 2013 Aug;15(8):948-57. doi: 10.1038/ncb2801. Epub 2013 Jul 14. PMID:23851487 PMCID: PMC3767134 read article


Atkins BD, Yoshida S, Saito K, Wu CF, Lew DJ, Pellman D. Inhibition of Cdc42 during mitotic exit is required for cytokinesis. J Cell Biol. 2013 Jul 22;202(2):231-40. doi: 10.1083/jcb.201301090. PMID: 23878274 PMCID: PMC3718968 read article


Lehnert BP, Baker AE, Gaudry Q, Chiang AS, Wilson RI. Distinct roles of TRP channels in auditory transduction and amplification in Drosophila. Neuron. 2013 Jan 9;77(1):115-28. doi: 10.1016/j.neuron.2012.11.030. PMID: 23312520 PMCID: PMC3811118 read article


Guo G, Luc S, Marco E, Lin TW, Peng C, Kerenyi MA, Beyaz S, Kim W, Xu J, Das PP, Neff T, Zou K, Yuan GC, Orkin SH. Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire. Cell Stem Cell. 2013 Oct 3;13(4):492-505. doi: 10.1016/j.stem.2013.07.017. Epub 2013 Sep 12. PMID: 24035353 PMCID: PMC3845089 read article


Chang J, Burkett PR, Borges CM, Kuchroo VK, Turka LA, Chang CH. MyD88 is essential to sustain mTOR activation necessary to promote Th17 cell proliferation by linking IL-1 and IL-23 signaling. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2270-5. doi: 10.1073/pnas.1206048110. Epub 2013 Jan 22. PMID: 23341605 PMCID: PMC3568327 read article


Duncan MB, Yang C, Tanjore H, Boyle PM, Keskin D, Sugimoto H, Zeisberg M, Olsen BR, Kalluri R. Type XVIII collagen is essential for survival during acute liver injury in mice. Dis Model Mech. 2013 Jul;6(4):942-51. doi: 10.1242/dmm.011577. Epub 2013 Apr 4. PMID: 23580202 PMCID: PMC3701214 read article


Kim SG, Buel GR, and Blenis J. 2013. Nutrient regulation of the mTOR Complex 1 signaling pathway. Mol Cells. 2013 Jun;35(6):463-73. doi: 10.1007/s10059-013-0138-2. Epub 2013 May 20. PMID: 23694989 PMCID: PMC3887879


Buel GR, Kim SG, and Blenis J. 2013. mTORC1 Signaling Aids in CADalyzing Pyrimidine Biosynthesis. Cell Metab. 2013 May 7;17(5):633-5. doi: 10.1016/j.cmet.2013.04.018. PMID: 23663734


Kim SG, Hoffman GR, Poulogiannis G, Buel GR, Jang YJ, Lee KW, Kim BY, Erikson RL, Cantley LC, Choo AY, and Blenis J. 2013. Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. Mol Cell. 2013 Jan 10;49(1):172-85. doi: 10.1016/j.molcel.2012.10.003. Epub 2012 Nov 8. PMID: 23142078 PMCID: PMC3545014 read article


Harris JM; Esain V; Frechette GM; Harris LJ; Cox AG; Cortes M; Garnaas MK; Carroll KJ; Cutting CC; Khan T; Elks PM; Renshaw SA; Dickinson BC; Chang CJ; Murphy MP; Paw BH; Vander Heiden MG; Goessling W; North TE. Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood. 2013 Mar 28;121(13):2483-93. doi: 10.1182/blood-2012-12-471201. Epub 2013 Jan 22. PMID: 23341543 PMCID: PMC3612858 read article


Jemielity S, Wang JJ, Chan YK, Ahmed AA, Li W, Monahan S, Bu X, Farzan M, Freeman GJ, Umetsu DT, Dekruyff RH, Choe H. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog. 2013 Mar;9(3):e1003232. doi: 10.1371/journal.ppat.1003232. Epub 2013 Mar 28. PMID:23555248. PMCID:PMC3610696. read article


Gat-Viks I, Chevrier N, Wilentzik R, Eisenhaure T, Raychowdhury R, Steuerman Y, Shalek AK, Hacohen N, Amit I, Regev A. Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli. Nat Biotechnol. 2013 Apr;31(4):342-9. doi: 10.1038/nbt.2519. Epub 2013 Mar 17. PMID: 23503680 PMCID: PMC3622156 read article


Tonti E, Jiménez de Oya N, Galliverti G, Moseman EA, Di Lucia P, Amabile A, Sammicheli S, De Giovanni M, Sironi L, Chevrier N, Sitia G, Gennari L, Guidotti LG, von Andrian UH, Iannacone M. Bisphosphonates target B cells to enhance humoral immune responses. Cell Rep. 2013 Oct 31;5(2):323-30. doi: 10.1016/j.celrep.2013.09.004. Epub 2013 Oct 10. PMID: 24120862 PMCID: PMC3838640 read article


Buchwalter G, Hickey MM, Cromer A, Selfors LM, Gunawardane RN, Frishman J, Jeselsohn R, Lim E, Chi D, Fu X, Schiff R, Brown M, Brugge JS. PDEF Promotes Luminal Differentiation and Acts as a Survival Factor for ER-Positive Breast Cancer Cells. Cancer Cell. 2013 Jun 10;23(6):753-67. doi: 10.1016/j.ccr.2013.04.026. PMID:23764000. PMCID:PMC3711136.


Hull CA, Chu Y, Thanawala M, Regehr WG. Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. J Neurosci. 2013 Apr 3;33(14):5895-902. doi: 10.1523/JNEUROSCI.4052-12.2013. PMID: 23554471 PMCID: PMC3641191 read article


Ciarlo CA, Zon LI. A model for primary melanoma of the CNS implicates NRAS. Cancer Discov. 2013 Apr;3(4):382-3. doi: 10.1158/2159-8290.CD-13-0076. PMID: 23580282


Fang R, Chen F, Dong Z, Hu D, Barbera AJ, Clark EA, Fang J, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Yang H, Wang P, Simon MD, Zhou Q, Li J, Marynick MP, Li X, Lu H, Kaiser UB, Kingston RE, Xu Y, Shi YG. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation. Mol Cell. 2013 Feb 7;49(3):558-70. doi: 10.1016/j.molcel.2012.11.019. Epub 2012 Dec 20. PMID: 23260659 PMCID: PMC3625064 read article


Kung J, Colognori D, Lee J. (2013) Long noncoding RNAs: past, present, and future. Genetics. 2013 Mar;193(3):651-69. doi: 10.1534/genetics.112.146704. PMID: 23463798. PMCID:PMC3583990. read article


Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, Henske EP, Haigis MC, Cantley LC, Stephanopoulos G, Yu J, Blenis J. The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4. Cell. 2013 May 9;153(4):840-54. doi: 10.1016/j.cell.2013.04.023. PMID: 23663782 PMCID: PMC3684628


Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013 Aug 22;500(7463):477-81. doi: 10.1038/nature12433. Epub 2013 Aug 7. PMID: 23925113 PMCID: PMC3821869 read article


CA. Gifford*, MJ. Ziller*, H Gu, C Trapnell, J Donaghey, A Tsankov, AK. Shalek, DR Kelley, R Issner, X Zhang, M Coyne, JL Fostel, L Holmes, J Meldrim, C Epstein, H Park, A Regev, O Kohlbacher, J Rinn, A Gnirke, BE Bernstein and A Meissner. Transcriptional and Epigenetic Dynamics During Specification of Human Embryonic Stem Cells. Cell. 2013 May 23;153(5):1149-63. doi: 10.1016/j.cell.2013.04.037. Epub 2013 May 9. PMID: 23664763 PMCID: PMC3709577


Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR. Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol. 2013 Oct;31(10):898-907. doi: 10.1038/nbt.2682. Epub 2013 Sep 8. PMID: 24013197


Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science. 2013 Nov 22;342(6161):971-6. doi: 10.1126/science.1240537. PMID: 24264990 PMCID: PMC4048947 read article


Cortez-Retamozo V, Engblom C, Pittet MJ. Remote control of macrophage production by cancer. Oncoimmunology. 2013 May 1;2(5):e24183. PMID: 23762799 PMCID: PMC3667905 read article


Eshel N, Tian J, Uchida N. Opening the black box: dopamine, predictions, and learning. Trends Cogn Sci. 2013 Sep;17(9):430-1. doi: 10.1016/j.tics.2013.06.010. Epub 2013 Jul 3. PMID: 23830895. PMCID: PMC3811049. NIHMSID: NIHMS501083.


Uchida N, Eshel N, Watabe-Uchida M. Division of labor for division: inhibitory interneurons with different spatial landscapes in the olfactory system. Neuron. 2013 Dec 4;80(5):1106-9. doi: 10.1016/j.neuron.2013.11.013. PMID: 24314722


Cosker KE, Pazyra-Murphy MF, Fenstermacher SJ, Segal RA. Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration. J Neurosci. 2013 Mar 20;33(12):5195-207. doi: 10.1523/JNEUROSCI.3862-12.2013. PMID: 23516285 PMCID: PMC3866501 read article


Torella JP, Ford TJ, Kim SN, Chen AM, Way JC, Silver PA. Tailored fatty acid synthesis via dynamic control of fatty acid elongation. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11290-5. doi: 10.1073/pnas.1307129110. Epub 2013 Jun 24. PMID: 23798438 PMCID: PMC3710846 read article


Froberg JE, Yang L, Lee JT. Guided by RNAs: X-inactivation as a model for lncRNA function. J Mol Biol. 2013 Oct 9;425(19):3698-706. doi: 10.1016/j.jmb.2013.06.031. Epub 2013 Jun 28. PMID: 23816838 PMCID: PMC3771680


Quinlan BD, Gardner MR, Joshi VR, Chiang JJ, Farzan M. Direct expression and validation of phage-selected pepti de variants in mammalian cells. J Biol Chem. 2013 Jun 28;288(26):18803-10. doi: 10.1074/jbc.M113.452839. Epub 2013 May 10. PMID:23667257 PMCID: PMC3696656


Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Vander Heiden MG, Goessling W, North TE. Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood. 2013 Mar 28;121(13):2483-93. doi: 10.1182/blood-2012-12-471201. Epub 2013 Jan 22. PMID: 23341543 PMCID: PMC3612858 read article


Garris C, Pittet MJ. Therapeutically re-educating macrophages to treat GBM. Nat Med. 2013 Oct;19(10):1207-8. doi: 10.1038/nm.3355. PMID:24100977


Laurent G, German NJ, Saha AK, de Boer VC, Davies M, Koves TR, Dephoure N, Fischer F, Boanca G, Vaitheesvaran B, Lovitch SB, Sharpe AH, Kurland IJ, Steegborn C, Gygi SP, Muoio DM, Ruderman NB, Haigis MC. SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol Cell. 2013 Jun 6;50(5):686-98. doi: 10.1016/j.molcel.2013.05.012. PMID: 23746352 PMCID: PMC3721068


Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, Cerione R, Blenis J, Clish CB, Kimmelman A, Deng CX, Haigis MC. SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism. Cancer Cell. 2013 Apr 15;23(4):450-63. doi: 10.1016/j.ccr.2013.02.024. Epub 2013 Apr 4. PMID: 23562301 PMCID: PMC3650305


Yang MH, Laurent G, Bause AS, Spang R, German N, Haigis MC, Haigis KM. HDAC6 and SIRT2 regulate the acetylation state and oncogenic activity of mutant K-RAS. Mol Cancer Res. 2013 Sep;11(9):1072-7. doi: 10.1158/1541-7786.MCR-13-0040-T. Epub 2013 May 30. PMID: 23723075 PMCID: PMC3778089


Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Res. 2013 Oct 15;73(20):6289-98. doi: 10.1158/0008-5472.CAN-13-1616. Epub 2013 Aug 26. PMID: 23980093 PMCID: PMC3856255


Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC. Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discov. 2013 Sep;3(9):1044-57. doi: 10.1158/2159-8290.CD-12-0592. Epub 2013 Jun 13. PMID: 23764425 PMCID: PMC3770815


Wilson-Grady JT, Haas W, Gygi SP. Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods. 2013 Jun 15;61(3):277-86. doi: 10.1016/j.ymeth.2013.03.031. Epub 2013 Apr 6. PMID: 23567750


Wilson-Grady JT, Haas W, Gygi SP. Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods. 2013 Jun 15;61(3):277-86. doi: 10.1016/j.ymeth.2013.03.031. Epub 2013 Apr 6. PMID: 3567750


Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. J Clin Invest. 2013 Sep 3;123(9):4010-22. doi: 10.1172/JCI69443. Epub 2013 Aug 15. PMID: 23945236. PMCID: PMC3754267


Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC. The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. J Exp Med. 2013 Aug 26;210(9):1793-806. doi: 10.1084/jem.20111790. Epub 2013 Aug 5. PMID: 23918955. PMCID: PMC3754873


Greenblatt MB, Shim JH, Glimcher LH. Mitogen-Activated Protein Kinase Pathways in Osteoblasts. Annu Rev Cell Dev Biol. 2013 May 31. [Epub ahead of print] PMID: 23725048


Greenblatt MB, Aliprantis AO. The immune pathogenesis of scleroderma: context is everything. Curr Rheumatol Rep. 2013 Jan;15(1):297. doi: 10.1007/s11926-012-0297-8. Review. PMID: 23288576. PMCID: PMC3539168


Greenblatt MB, Ritter SY, Wright J, Tsang K, Hu D, Glimcher LH, Aliprantis AO. NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19914-9. doi: 10.1073/pnas.1320036110. Epub 2013 Nov 18. PMID:24248346. PMCID: PMC3856808


Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki S, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RN, Hill AV, Vannberg FO, Rinn JL; 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC. Identifying recent adaptations in large-scale genomic data. Cell. 2013 Feb 14;152(4):703-13. doi: 10.1016/j.cell.2013.01.035. PMID: 23415221 PMCID: PMC3674781 read article


Guo MH, Stoler J, Lui J, Nilsson O, Bianchi DW, Hirschhorn JN, Dauber A. Redefining the progeroid form of Ehlers-Danlos syndrome: report of the fourth patient with B4GALT7 deficiency and review of the literature. Am J Med Genet A. 2013 Oct;161(10):2519-27. doi: 10.1002/ajmg.a.36128. Epub 2013 Aug 16. PMID: 23956117PMCID: PMC3788078


Hanson KK, Ressurreição AS, Buchholz K, Prudêncio M, Herman-Ornelas JD, Rebelo M, Beatty WL, Wirth DF, Hänscheid T, Moreira R, Marti M, Mota MM. Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2838-47. doi: 10.1073/pnas.1306097110. Epub 2013 Jul 8. PMID: 23836641


Hinshaw SM, Harrison SC. An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation. Cell Rep. 2013 Oct 17;5(1):29-36. doi: 10.1016/j.celrep.2013.08.036. Epub 2013 Sep 26. PMID:24075991 PMCID:PMC3888643


Ho BT, Basler M, Mekalanos JJ. Type 6 secretion system-mediated immunity to type 4 secretion system-mediated gene transfer. Science. 2013 Oct 11;342(6155):250-3. doi: 10.1126/science.1243745. PMID: 24115441


Dong TG, Ho BT, Yoder-Himes DR, Mekalanos JJ. Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2623-8. doi: 10.1073/pnas.1222783110. Epub 2013 Jan 29. PMID: 23362380 PMCID: PMC3574944 read article


Basler M, Ho BT, Mekalanos JJ. Tit-for-tat: type VI secretion system counterattack during bacterial cell-cell interactions. Cell. 2013 Feb 14;152(4):884-94. doi: 10.1016/j.cell.2013.01.042. PMID: 23415234 PMCID: PMC3616380 read article


Shneider MM, Buth SA, Ho BT, Basler M, Mekalanos JJ, Leiman PG. PAAR-repeat proteins sharpen and diversify the type VI secretion system spike. Nature. 2013 Aug 15;500(7462):350-3. doi: 10.1038/nature12453. Epub 2013 Aug 7. PMID: 23925114 PMCID: PMC3792578 read article


Hogdal LJ, Letai A. BCL-2 inhibition: stemming the tide of myeloid malignancies. Cell Stem Cell. 2013 Mar 7;12(3):269-70. doi: 10.1016/j.stem.2013.02.006. PMID: 23472867 PMCID: PMC3705714 read article


Zhang R, Huynh A, Whitcher G, Chang J, Maltzman JS, Turka LA. An Obligate Cell-Intrinsic Function for CD28 in Regulatory T cells. J Clin Invest. 2013 Feb 1;123(2):580-93. doi: 10.1172/JCI65013. Epub 2013 Jan 2. PMID: 23281398 PMCID: PMC3561819 read article


Huynh A and Turka LA. Control of T cell tolerance by PTEN. Ann N Y Acad Sci. 2013 Mar;1280:27-9. doi: 10.1111/nyas.12015. PMID: 23551099


Gu X, Yu JJ, Ilter D, Blenis N, Henske EP, Blenis J. Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14960-5. doi: 10.1073/pnas.1309110110. Epub 2013 Aug 27. PMID: 23983265 PMCID: PMC3773757 read article


Jiang S, Willox B, Zhou H, Holthaus AM, Wang A, Shi TT, Maruo S, Kharchenko PV, Johannsen EC, Kieff E, Zhao B. Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):421-6. doi: 10.1073/pnas.1321704111. Epub 2013 Dec 16. PMID: 24344258 PMCID: PMC3890834


Portal D, Zhou H, Zhao B, Kharchenko PV, Lowry E, Wong L, Quackenbush J, Holloway D, Jiang S, Lu Y, Kieff E. Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18537-42. doi: 10.1073/pnas.1317608110. Epub 2013 Oct 28. PMID: 24167291 PMCID: PMC3832032


Duncan MB, Yang C, Tanjore H, Boyle PM, Keskin D, Sugimoto H, Zeisberg M, Olsen BR, Kalluri R. Type XVIII collagen is essential for survival during acute liver injury in mice. Dis Model Mech. 2013 Jul;6(4):942-51. doi: 10.1242/dmm.011577. Epub 2013 Apr 4. PMID: 23580202 PMCID: PMC3701214 read article


Li CM, Chen G, Dayton TL, Kim-Kiselak C, Hoersch S, Whittaker CA, Bronson RT, Beer DG, Winslow MM, Jacks T. Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma. Genes Dev. 2013 Jul 15;27(14):1557-67. doi: 10.1101/gad.222745.113. PMID: 23873940 PMCID: PMC3731545 read article


Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. PMID: 23907390 PMCID: PMC3799423 read article


Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 5;155(6):1282-95. doi: 10.1016/j.cell.2013.10.054. PMID: 24315098 PMCID: PMC3894749


Kowalko JE, Rohner N, Rompani SB, Peterson BK, Linden TA, Yoshizawa M, Kay EH, Weber J, Hoekstra HE, Jeffery WR, Borowsky R, Tabin CJ. Loss of schooling behavior in cavefish through sight-dependent and sight-independent mechanisms. Curr Biol. 2013 Oct 7;23(19):1874-83. doi: 10.1016/j.cub.2013.07.056. Epub 2013 Sep 12. PMID: 24035545 PMCID: PMC3904651


Rohner N, Jarosz DF, Kowalko JE, Yoshizawa M, Jeffery WR, Borowsky RL, Lindquist S, Tabin CJ. Cryptic variation in morphological evolution: HSP90 as a capacitor for loss of eyes in cavefish. Science. 2013 Dec 13;342(6164):1372-5. doi: 10.1126/science.1240276. PMID: 24337296


Kowalko JE, Rohner N, Linden TA, Rompani SB, Warren WC, Borowsky R, Tabin CJ, Jeffery WR, Yoshizawa M. Convergence in feeding posture occurs through different genetic loci in independently evolved cave populations of Astyanax mexicanus. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16933-8. doi: 10.1073/pnas.1317192110. Epub 2013 Oct 1. PMID: 24085851 PMCID: PMC3801050


Oksenych V, Kumar V, Liu X, Guo C, Schwer B, Zha S, Alt FW. Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2234-9. doi: 10.1073/pnas.1222573110. Epub 2013 Jan 23. PMID: 23345432 PMCID: PMC3568359 read article


Kung JT, Colognori D, Lee JT. Long noncoding RNAs: past, present, and future.Genetics. 2013 Mar;193(3):651-69. doi: 10.1534/genetics.112.146704. PMID: 23463798 PMCID: PMC3583990 read article


Kung JT, Lee JT. RNA in the loop. Dev Cell. 2013 Mar 25;24(6):565-7. doi: 10.1016/j.devcel.2013.03.009. PMID: 23537627 PMCID: PMC3777248 read article


Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ. Angiotensin II drives the production of tumor-promoting macrophages. Immunity. 2013 Feb 21;38(2):296-308. doi: 10.1016/j.immuni.2012.10.015. Epub 2013 Jan 17. PMID: 23333075 PMCID: PMC3582771 read article


Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 5;155(6):1282-95. doi: 10.1016/j.cell.2013.10.054. PMID: 24315098 PMCID: PMC3894749


Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G, Koeglsperger T, Dake B, Wu PM, Doykan CE, Fanek Z, Liu L, Chen Z,Rothstein JD, Ransohoff RM, Gygi SP, Antel JP, Weiner HL. Identification of a unique TGF-β-dependent molecular and functional signature in microglia. Nat Neurosci. 2014 Jan;17(1):131-43. doi: 10.1038/nn.3599. Epub 2013 Dec 8. PMID: 24316888


Lee RS, Roberts CW. Rhabdoid tumors: an initial clue to the role of chromatin remodeling in cancer. Brain Pathol. 2013 Mar;23(2):200-5. doi: 10.1111/bpa.12021. PMID: 23432645


Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, Ramos AH, Pugh TJ, Stransky N, Helman E, Kim J, Sougnez C, Ambrogio L, Nickerson E, Shefler E, Cortés ML, Auclair D, Saksena G, Voet D, Noble M, Dicara D, Lin P, Lichtenstein L, Heiman DI, Fennell T, Imielinski M, Hernandez B, Hodis E, Baca S, Dulak AM, Lohr J, Landau D-A, Wu CJ, Melendez-Zajgla J, Hidalgo-Miranda A, Koren A, McCarroll SA, Mora J, Lee RS, Crompton B, Onofrio R, Parkin M, Winckler W, Ardlie K, Gabriel SB, Roberts CWM, Biegel JA, Stegmaier K, Bass AJ, Garraway LA, Meyerson M, Golub TR, Gordenin DA, Sunyaev S, Lander ES, Getz G. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013 Jul 11;499(7457):214-8. doi: 10.1038/nature12213. Epub 2013 Jun 16. PMID: 23770567 PMCID: PMC3919509 read article


Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, Pillai MR, Ratcliffe PJ, Coleman ML, Bix M, Tantin D, Park H, Kuchroo VK, Regev A. Dynamic regulatory network controlling TH17 cell differentiation. Nature. 2013 Apr 25;496(7446):461-8. doi: 10.1038/nature11981. Epub 2013 Mar 6. PMID: 23467089 PMCID: PMC3637864 read article


Wu C, Pot C, Apetoh L, Thalhamer T, Zhu B, Murugaiyan G, Xiao S, Lee Y, Rangachari M, Yosef N, Kuchroo VK. Metallothioneins negatively regulate IL-27-induced type 1 regulatory T-cell differentiation. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7802-7. doi: 10.1073/pnas.1211776110. Epub 2013 Apr 29. PMID: 23630250 PMCID: PMC3651423 read article


Schafer DP, Lehrman EK, Stevens B. The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS. Glia. 2013 Jan;61(1):24-36. doi: 10.1002/glia.22389. Epub 2012 Jul 24. PMID: 22829357


Lim ET, Raychaudhuri S, Sanders SJ, Stevens C, Sabo A, MacArthur DG, Neale BM, Kirby A, Ruderfer DM, Fromer M, Lek M, Liu L, Flannick J, Ripke S, Nagaswamy U, Muzny D, Reid JG, Hawes A, Newsham I, Wu Y, Lewis L, Dinh H, Gross S, Wang LS, Lin CF, Valladares O, Gabriel SB, dePristo M, Altshuler DM, Purcell SM; NHLBI Exome Sequencing Project, State MW, Boerwinkle E, Buxbaum JD, Cook EH, Gibbs RA, Schellenberg GD, Sutcliffe JS, Devlin B, Roeder K, Daly MJ. Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron. 2013 Jan 23;77(2):235-42. doi: 10.1016/j.neuron.2012.12.029. PMID: 23352160 PMCID: PMC3613849 read article


He X, Sanders SJ, Liu L, De Rubeis S, Lim ET, Sutcliffe JS, Schellenberg GD, Gibbs RA, Daly MJ, Buxbaum JD, State MW, Devlin B, Roeder K. Integrated model of de novo and inherited genetic variants yields greater power to identify risk genes. PLoS Genet. 2013;9(8):e1003671. doi: 10.1371/journal.pgen.1003671. Epub 2013 Aug 15. PMID: 23966865 PMCID: PMC3744441 read article


Yu TW, Chahrour MH, Coulter ME, Jiralerspong S, Okamura-Ikeda K, Ataman B, Schmitz-Abe K, Harmin DA, Adli M, Malik AN, D'Gama AM, Lim ET, Sanders SJ, Mochida GH, Partlow JN, Sunu CM, Felie JM, Rodriguez J, Nasir RH, Ware J, Joseph RM, Hill RS, Kwan BY, Al-Saffar M, Mukaddes NM, Hashmi A, Balkhy S, Gascon GG, Hisama FM, LeClair E, Poduri A, Oner O, Al-Saad S, Al-Awadi SA, Bastaki L, Ben-Omran T, Teebi AS, Al-Gazali L, Eapen V, Stevens CR, Rappaport L, Gabriel SB, Markianos K, State MW, Greenberg ME, Taniguchi H, Braverman NE, Morrow EM, Walsh CA. Using whole-exome sequencing to identify inherited causes of autism. Neuron. 2013 Jan 23;77(2):259-73. doi: 10.1016/j.neuron.2012.11.002. PMID: 23352163 PMCID: PMC3694430 read article


Liu L, Sabo A, Neale BM, Nagaswamy U, Stevens C, Lim E, Bodea CA, Muzny D, Reid JG, Banks E, Coon H, Depristo M, Dinh H, Fennel T, Flannick J, Gabriel S, Garimella K, Gross S, Hawes A, Lewis L, Makarov V, Maguire J, Newsham I, Poplin R, Ripke S, Shakir K, Samocha KE, Wu Y, Boerwinkle E, Buxbaum JD, Cook EH Jr, Devlin B, Schellenberg GD, Sutcliffe JS, Daly MJ, Gibbs RA, Roeder K. Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls. PLoS Genet. 2013 Apr;9(4):e1003443. doi: 10.1371/journal.pgen.1003443. Epub 2013 Apr 11. PMID: 23593035 PMCID: PMC3623759 read article


Margolin DH, Kousi M, Chan YM, Lim ET, Schmahmann JD, Hadjivassiliou M, Hall JE, Adam I, Dwyer A, Plummer L, Aldrin SV, O'Rourke J, Kirby A, Lage K, Milunsky A, Milunsky JM, Chan J, Hedley-Whyte ET, Daly MJ, Katsanis N, Seminara SB. Ataxia, dementia, and hypogonadotropism caused by disordered ubiquitination. N Engl J Med. 2013 May 23;368(21):1992-2003. doi: 10.1056/NEJMoa1215993. Epub 2013 May 8. PMID: 23656588 PMCID: PMC3738065 read article


Mannstadt M, Harris M, Bravenboer B, Chitturi S, Dreijerink KM, Lambright DG, Lim ET, Daly MJ, Gabriel S, Jüppner H. Germline mutations affecting Gα11 in hypoparathyroidism. N Engl J Med. 2013 Jun 27;368(26):2532-4. doi: 10.1056/NEJMc1300278. PMID: 23802536 PMCID: PMC3750735 read article


Liu LY, Fox CS, North TE, Goessling W. Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development. Dis Model Mech. 2013 Sep;6(5):1271-8. doi: 10.1242/dmm.011726. Epub 2013 Jun 27. PMID: 23813869 PMCID: PMC3759346 read article


Liu WW, Wilson RI. Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10294-9. doi: 10.1073/pnas.1220560110. Epub 2013 May 31. PMID: 23729809 PMCID: PMC3690841 read article


Liu WW, Wilson RI. Transient and specific inactivation of Drosophila neurons in vivo using a native ligand-gated ion channel. Curr Biol. 2013 Jul 8;23(13):1202-8. doi: 10.1016/j.cub.2013.05.016. Epub 2013 Jun 13. PMID: 23770187 PMCID: PMC3725270


Morgan AM, Lo J, Fisher DE. How does pheomelanin synthesis contribute to melanomagenesis?: Two distinct mechanisms could explain the carcinogenicity of pheomelanin synthesis. Bioessays. 2013 Aug;35(8):672-6. doi: 10.1002/bies.201300020. Epub 2013 May 7. PMID: 23650156


Henrickson SE, Perro M, Loughhead SM, Senman B, Stutte S, Quigley M, Alexe G, Iannacone M, Flynn MP, Omid S, Jesneck JL, Imam S, Mempel TR, Mazo IB, Haining WN, von Andrian UH. Antigen availability determines CD8⁺ T cell-dendritic cell interaction kinetics and memory fate decisions. Immunity. 2013 Sep 19;39(3):496-507. doi: 10.1016/j.immuni.2013.08.034. PMID: 24054328 PMCID: PMC3914670


Lutas A, Yellen G. The ketogenic diet: metabolic influences on brain excitability and epilepsy. Trends Neurosci. 2013 Jan;36(1):32-40. doi: 10.1016/j.tins.2012.11.005. Epub 2012 Dec 8. PMID: 23228828 PMCID: PMC3534786 read article


Dettmer U, Newman AJ, Luth ES, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of α-synuclein and β-synuclein in neurons and non-neural cells. J Biol Chem. 2013 Mar 1;288(9):6371-85. doi: 10.1074/jbc.M112.403311. Epub 2013 Jan 14. PMID: 23319586 PMCID: PMC3585072 read article


Sciaranghella G, Tong N, Mahan AE, Suscovich TJ, Alter G. Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection. AIDS. 2013 Jan 14;27(2):175-80. doi: 10.1097/QAD.0b013e32835bd1f0. PMID: 23135171 PMCID: PMC3729211 read article


Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies. PLoS Pathog. 2013 Nov;9(11):e1003754. doi: 10.1371/journal.ppat.1003754. Epub 2013 Nov 21. PMID: 24278016 PMCID: PMC3836729 read article


Malhotra D, Fletcher AL, Turley SJ. Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity. Immunol Rev. 2013 Jan;251(1):160-76. doi: 10.1111/imr.12023. PMID: 23278748 PMCID: PMC3539229 read article


Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C; Immunological Genome Consortium, Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S. The transcriptional landscape of αβ T cell differentiation. Nat Immunol. 2013 Jun;14(6):619-32. doi: 10.1038/ni.2590. Epub 2013 May 5. PMID: 23644507 PMCID: PMC3660436 read article


Jojic V1, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D; Immunological Genome Project Consortium, Best AJ, Knell J, Goldrath A, Jojic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S. Identification of transcriptional regulators in the mouse immune system. Nat Immunol. 2013 Jun;14(6):633-43. doi: 10.1038/ni.2587. Epub 2013 Apr 28. PMID: 23624555 PMCID: PMC3690947 read article


Fuchs TA, Alvarez JJ, Martinod K, Bhandari AA, Kaufman RM, Wagner DD. Neutrophils release extracellular DNA traps during storage of red blood cell units. Transfusion. 2013 Dec;53(12):3210-6. doi: 10.1111/trf.12203. Epub 2013 Apr 8. PMID: 23560771 PMCID: PMC3728163


Martinod K, Demers M, Fuchs TA, Wong SL, Brill A, Gallant M, Hu J, Wang Y, Wagner DD. Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8674-9. doi: 10.1073/pnas.1301059110. Epub 2013 May 6. PMID: 23650392 PMCID: PMC3666755 read article


Borissoff JI, Joosen IA, Versteylen MO, Brill A, Fuchs TA, Savchenko AS, Gallant M, Martinod K, Ten Cate H, Hofstra L, Crijns HJ, Wagner DD, Kietselaer BL. Elevated levels of circulating DNA and chromatin are independently associated with severe coronary atherosclerosis and a prothrombotic state. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):2032-40. doi: 10.1161/ATVBAHA.113.301627. Epub 2013 Jul 1. PMID: 3818485 PMCID: PMC3806482


Savchenko AS, Martinod K, Seidman MA, Wong SL, Borissoff JI, Piazza G, Libby P, Goldhaber SZ, Mitchell RN, Wagner DD. Neutrophil extracellular traps form predominantly during the organizing stage of human venous thromboembolism development. J Thromb Haemost. 2014 Jun;12(6):860-70. doi: 10.1111/jth.12571. PMID: 24674135


Martinod K, Wagner DD. Thrombosis: tangled up in NETs. Blood. 2014 May 1;123(18):2768-76. doi: 10.1182/blood-2013-10-463646. Epub 2013 Dec 23. PMID: 24366358 PMCID: PMC4007606


McCarthy KR, Schmidt AG, Kirmaier A, Wyand AL, Newman RM, Johnson WE. Gain-of-sensitivity mutations in a Trim5-resistant primary isolate of pathogenic SIV identify two independent conserved determinants of Trim5α specificity. PLoS Pathog. 2013 May;9(5):e1003352. doi: 10.1371/journal.ppat.1003352. Epub 2013 May 9. PMID: 23675300 PMCID: PMC3649984 read article


Krupp A, McCarthy KR, Ooms M, Letko M, Morgan JS, Simon V, Johnson WE. APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host. PLoS Pathog. 2013;9(10):e1003641. doi: 10.1371/journal.ppat.1003641. Epub 2013 Oct 3. PMID: 24098115 PMCID: PMC3789815 read article


McLachlan IG, Heiman MG. Shaping dendrites with machinery borrowed from epithelia. Curr Opin Neurobiol. 2013 Dec;23(6):1005-10. doi: 10.1016/j.conb.2013.06.011. Epub 2013 Jul 18. PMID: 23871793


Teodoro RO, Pekkurnaz G, Nasser A, Higashi-Kovtun ME, Balakireva M, McLachlan IG, Camonis J, Schwarz TL. Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst. EMBO J. 2013 Jul 17;32(14):2039-55. doi: 10.1038/emboj.2013.147. Epub 2013 Jun 28. PMID: 23812009 PMCID: PMC3715865


Doan T, Coleman J, Marquis KA, Meeske AJ, Burton BM, Karatekin E, Rudner DZ. FisB mediates membrane fission during sporulation in Bacillus subtilis. Genes Dev. 2013 Feb 1;27(3):322-34. doi: 10.1101/gad.209049.112. PMID: 23388828 PMCID: PMC3576517 read article


Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MA, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013 Dec;9(12):840-8. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27.PMID: 24161946


Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling. Cancer Cell. 2013 Jul 8;24(1):45-58. doi: 10.1016/j.ccr.2013.05.004. Epub 2013 Jun 13. PMID: 23770013. PMCID: PMC3746037


Montero-Diez C, Deighan P, Osmundson J, Darst SA, Hochschild A. Phage-encoded inhibitor of Staphylococcus aureus transcription exerts context-dependent effects on promoter function in a modified Escherichia coli-based transcription system. J Bacteriol. 2013 Aug;195(16):3621-8. doi: 10.1128/JB.00499-13. Epub 2013 Jun 7. PMID: 23749973 PMCID: PMC3754564 read article


Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013 Apr 4;496(7443):101-5. doi: 10.1038/nature12040. Epub 2013 Mar 27. PMID: 23535601 PMCID: PMC3656466 read article


Nedelcu D, Liu J, Xu Y, Jao C, Salic A. Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling. Nat Chem Biol. 2013 Sep;9(9):557-64. doi: 10.1038/nchembio.1290. Epub 2013 Jul 7. PMID: 23831757 PMCID: PMC3749252 read article


Chellappa V, Taylor KN, Pedrick K, Donado C, Netravali IA, Haider K, Cariappa A, Dalomba NF, and Pillai S. M89V sialic acid acetyl esterase and all other non-synonymous common variants of this gene are catalytically normal. PLoS One. 2013;8(1):e53453. doi: 10.1371/journal.pone.0053453. Epub 2013 Jan 7. PMID: 23308225 PMCID: PMC3538537 read article


Shyh-Chang N, Daley GQ, Cantley LC. Stem cell metabolism in tissue development and aging. Development. 2013 Jun;140(12):2535-47. doi: 10.1242/dev.091777. PMID: 23715547 PMCID: PMC3666381


Shyh-Chang N, Daley GQ. Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell. 2013 Apr 4;12(4):395-406. doi: 10.1016/j.stem.2013.03.005. PMID: 23561442 PMCID: PMC3652335 read article


Shyh-Chang N, Locasale JW, Lyssiotis CA, Zheng Y, Teo RY, Ratanasirintrawoot S, Zhang J, Onder T, Unternaehrer JJ, Zhu H, Asara JM, Daley GQ, Cantley LC. Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science. 2013 Jan 11;339(6116):222-6. doi: 10.1126/science.1226603. Epub 2012 Nov 1. PMID: 23118012 PMCID: PMC3652341 read article


Shyh-Chang N, Zhu H, Yvanka de Soysa T, Shinoda G, Seligson MT, Tsanov KM, Nguyen L, Asara JM, Cantley LC, Daley GQ. Lin28 enhances tissue repair by reprogramming cellular metabolism. Cell. 2013 Nov 7;155(4):778-92. doi: 10.1016/j.cell.2013.09.059. PMID: 24209617 PMCID: PMC3917449


Shinoda G, Shyh-Chang N, Soysa TY, Zhu H, Seligson MT, Shah SP, Abo-Sido N, Yabuuchi A, Hagan JP, Gregory RI, Asara JM, Cantley LC, Moss EG, Daley GQ. Fetal deficiency of lin28 programs life-long aberrations in growth and glucose metabolism. Stem Cells. 2013 Aug;31(8):1563-73. doi: 10.1002/stem.1423. PMID: 23666760 PMCID: PMC3775935 read article


Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013 Apr 4;496(7443):101-5. doi: 10.1038/nature12040. Epub 2013 Mar 27. PMID: 23535601 PMCID: PMC3656466 read article


Vander Lugt B, Tubo NJ, Nizza ST, Boes M, Malissen B, Fuhlbrigge RC, Kupper TS, Campbell JJ. CCR7 plays no appreciable role in trafficking of central memory CD4 T cells to lymph nodes. J Immunol. 2013 Sep 15;191(6):3119-27. doi: 10.4049/jimmunol.1200938. Epub 2013 Aug 9. PMID: 23935190 PMCID: PMC3784989


Lienert F, Torella JP, Chen JH, Norsworthy M, Richardson RR, Silver PA. Two- and three-input TALE-based AND logic computation in embryonic stem cells. Nucleic Acids Res. 2013 Nov;41(21):9967-75. doi: 10.1093/nar/gkt758. Epub 2013 Aug 27. PMID: 23982518 PMCID: PMC3834826 read article


Beier KT, Saunders AB, Oldenburg IA, Sabatini BL, Cepko CL. Vesicular stomatitis virus with the rabies virus glycoprotein directs retrograde transsynaptic transport among neurons in vivo. Front Neural Circuits. 2013 Feb 7;7:11. doi: 10.3389/fncir.2013.00011. eCollection 2013. PMID: 23403489 PMCID: PMC3566411 read article


McCluskey AJ, Olive AJ, Starnbach MN, Collier RJ. Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen. Mol Oncol. 2013 Jun;7(3):440-51. doi: 10.1016/j.molonc.2012.12.003. Epub 2012 Dec 19. PMID: 23290417 PMCID: PMC3621010


Reiling JH, Olive AJ, Sanyal S, Carette JE, Brummelkamp TR, Ploegh HL, Starnbach MN, Sabatini DM. A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens. Nat Cell Biol. 2013 Dec;15(12):1473-85. doi: 10.1038/ncb2865. Epub 2013 Nov 3. PMID: 24185178 PMCID: PMC3965854 read article


McLaughlin SK, Olsen SN, Dake B, De Raedt T, Lim E, Bronson RT, Beroukhim R, Polyak K, Brown M, Kuperwasser C, Cichowski K. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell. 2013 Sep 9;24(3):365-78. doi: 10.1016/j.ccr.2013.08.004. PMID: 24029233 PMCID: PMC3822334


Ali F, Otchy TM, Pehlevan C, Fantana AL, Burak Y, Ölveczky BP. The basal ganglia is necessary for learning spectral, but not temporal, features of birdsong. Neuron. 2013 Oct 16;80(2):494-506. doi: 10.1016/j.neuron.2013.07.049. Epub 2013 Sep 26. PMID: 24075977 PMCID: PMC3929499


Shah VB, Shi J, Hout DR, Oztop I, Krishnan L, Ahn J, Shotwell MS, Engelman A, Aiken C. The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating. J Virol. 2013 Jan;87(1):422-32. doi: 10.1128/JVI.07177-11. Epub 2012 Oct 24. PMID: 23097435 PMCID: PMC3536424 read article


Paik EJ, Mahony S, White RM, Price EN, Dibiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI. A cdx4-sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 2013 Nov 7;1(5):425-36. doi: 10.1016/j.stemcr.2013.10.001. eCollection 2013. PMID: 24286030 PMCID: PMC3841246


Wesemann DR, Portuguese AJ, Meyers RM, Gallagher MP, Cluff-Jones K, Magee JM, Panchakshari RA, Rodig SJ, Kepler TB, Alt FW. Microbial colonization influences early B-lineage development in the gut lamina propria. Nature. 2013 Sep 5;501(7465):112-5. doi: 10.1038/nature12496. Epub 2013 Aug 21. PMID: 23965619 PMCID: PMC3807868 read article


Pasquina LW, Santa Maria JP, Walker S. Teichoic acid biosynthesis as an antibiotic target. Curr Opin Microbiol. 2013 Oct;16(5):531-7. doi: 10.1016/j.mib.2013.06.014. Epub 2013 Jul 31. PMID: 23916223 PMCID: PMC3834221


Perry KJ, Higgins DE. A differential fluorescence-based genetic screen identifies Listeria monocytogenes determinants required for intracellular replication. J Bacteriol. 2013 Aug;195(15):3331-40. doi: 10.1128/JB.00210-13. Epub 2013 May 17. PMID: 23687268 PMCID: PMC3719552  read article


Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. 2013 Feb 28;152(5):1065-76. doi: 10.1016/j.cell.2013.01.036. PMID: 23452854 PMCID: PMC3587980 read article


Piccinotti S, Kirchhausen T, Whelan SP. Uptake of rabies virus into epithelial cells by clathrin-mediated endocytosis depends upon actin. J Virol. 2013 Nov;87(21):11637-47. doi: 10.1128/JVI.01648-13. Epub 2013 Aug 21. PMID: 23966407 PMCID: PMC3807345


Poddar R, Kawai R, Ölveczky BP. A fully automated high-throughput training system for rodents. PLoS One. 2013 Dec 6;8(12):e83171. doi: 10.1371/journal.pone.0083171. eCollection 2013. PMID: 24349451 PMCID: PMC3857823 read article


Penaloza-MacMaster P, Provine NM, Ra J, Borducchi EN, McNally A, Simmons NL, Iampietro MJ, Barouch DH. Alternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectors. J Virol. 2013 Feb;87(3):1373-84. doi: 10.1128/JVI.02058-12. Epub 2012 Nov 14. PMID: 23152535 PMCID: PMC3554181 read article


Im EJ, Borducchi EN, Provine NM, McNally AG, Li S, Frankel FR, Barouch DH. An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice. J Virol. 2013 Apr;87(8):4751-5. doi: 10.1128/JVI.03085-12. Epub 2013 Feb 6. PMID: 23388715 PMCID: PMC3624386 read article


Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL. In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell. 2013 Jul 8;24(1):45-58. doi: 10.1016/j.ccr.2013.05.004. Epub 2013 Jun 13. PMID: 23770013 PMCID: PMC3746037


Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MA, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013 Dec;9(12):840-8. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27. PMID: 24161946 PMCID: PMC4009363


Puram SV, Bonni A. Cell-intrinsic drivers of dendrite morphogenesis. Development. 2013 Dec;140(23):4657-71. doi: 10.1242/dev.087676. PMID: 24255095 PMCID: PMC3833426


Puram SV, Kim AH, Park HY, Anckar J, Bonni A. The ubiquitin receptor S5a/Rpn10 links centrosomal proteasomes with dendrite development in the mammalian brain. Cell Rep. 2013 Jul 11;4(1):19-30. doi: 10.1016/j.celrep.2013.06.006. Epub 2013 Jul 3. PMID: 23831032


Shay T, Jojic V, Zuk O, Rothamel K, Puyraimond-Zemmour D, Feng T, Wakamatsu E, Benoist C, Koller D, Regev A; ImmGen Consortium. Conservation and divergence in the transcriptional programs of the human and mouse immune systems. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2946-51. doi: 10.1073/pnas.1222738110. Epub 2013 Feb 4. PMID: 23382184 PMCID: PMC3581886 read article


Abyzov A1, Iskow R, Gokcumen O, Radke DW, Balasubramanian S, Pei B, Habegger L; 1000 Genomes Project Consortium, Lee C, Gerstein M. Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division. Genome Res. 2013 Dec;23(12):2042-52. doi: 10.1101/gr.154625.113. Epub 2013 Sep 11. PMID: 24026178 PMCID: PMC3847774  read article


Rahmberg AR, Neidermyer WJ Jr, Breed MW, Alvarez X, Midkiff CC, Piatak M Jr, Lifson JD, Evans DT. Tetherin upregulation in simian immunodeficiency virus-infected macaques. J Virol. 2013 Dec;87(24):13917-21. doi: 10.1128/JVI.01757-13. Epub 2013 Oct 9. PMID: 24109219 PMCID: PMC3838227


Shyh-Chang N, Locasale JW, Lyssiotis CA, Zheng Y, Teo RY, Ratanasirintrawoot S, Zhang J, Onder T, Unternaehrer JJ, Zhu H, Asara JM, Daley GQ, Cantley LC. Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science. 2013 Jan 11;339(6116):222-6. doi: 10.1126/science.1226603. Epub 2012 Nov 1. PMID: 23118012 PMCID: PMC3652341 read article


Ricoult SJ, Manning BD. The multifaceted role of mTORC1 in the control of lipid metabolism. EMBO Rep. 2013 Mar 1;14(3):242-51. doi: 10.1038/embor.2013.5. Epub 2012 Feb 12. PMID: 23399656 PMCID: PMC3589096 read article


Howell JJ, Ricoult SJ, Ben-Sahra I, Manning BD. A growing role for mTOR in promoting anabolic metabolism. Biochem Soc Trans. 2013 Aug;41(4):906-12. doi: 10.1042/BST20130041. PMID: 23863154


Roberson DP, Gudes S, Sprague JM, Patoski HA, Robson VK, Blasl F, Duan B, Oh SB, Bean BP, Ma Q, Binshtok AM, Woolf CJ. Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons. Nat Neurosci. 2013 Jul;16(7):910-8. doi: 10.1038/nn.3404. Epub 2013 May 19. PMID: 23685721 PMCID: PMC3695070 read article


Brenneis C, Kistner K, Puopolo M, Segal D, Roberson D, Sisignano M, Labocha S, Ferreirós N, Strominger A, Cobos EJ, Ghasemlou N, Geisslinger G, Reeh PW, Bean BP, Woolf CJ. Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing. J Neurosci. 2013 Jan 2;33(1):315-26. doi: 10.1523/JNEUROSCI.2804-12.2013. PMID: 23283344 PMCID: PMC3640269 read article


Yang FC, Tan T, Huang T, Christianson J, Samad OA, Liu Y, Roberson D, Davis BM, Ma Q. Genetic control of the segregation of pain-related sensory neurons innervating the cutaneous versus deep tissues. Cell Rep. 2013 Dec 12;5(5):1353-64. doi: 10.1016/j.celrep.2013.11.005. Epub 2013 Dec 5. PMID: 24316076 PMCID: PMC3895930


Praetorius C, Grill C, Stacey SN, Metcalf AM, Gorkin DU, Robinson KC, Van Otterloo E, Kim RS, Bergsteinsdottir K, Ogmundsdottir MH, Magnusdottir E, Mishra PJ, Davis SR, Guo T, Zaidi MR, Helgason AS, Sigurdsson MI, Meltzer PS, Merlino G, Petit V, Larue L, Loftus SK, Adams DR, Sobhiafshar U, Emre NC, Pavan WJ, Cornell R, Smith AG, McCallion AS, Fisher DE, Stefansson K, Sturm RA, Steingrimsson E. A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell. 2013 Nov 21;155(5):1022-33. doi: 10.1016/j.cell.2013.10.022. PMID: 24267888 PMCID: PMC3873608


White R, Rose K, Zon L. Zebrafish cancer: the state of the art and the path forward. Nat Rev Cancer. 2013 Sep;13(9):624-36. doi: 10.1038/nrc3589. PMID: 23969693


Venkatesh D, Ernandez T, Rosetti F, Batal I, Cullere X, Luscinskas FW, Zhang Y, Stavrakis G, García-Cardeña G, Horwitz BH, Mayadas TN. Endothelial TNF receptor 2 induces IRF1 transcription factor-dependent interferon-β autocrine signaling to promote monocyte recruitment. Immunity. 2013 May 23;38(5):1025-37. doi: 10.1016/j.immuni.2013.01.012. Epub 2013 Apr 25. PMID: 23623383 PMCID: PMC3760474


Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, Brigl M. Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1827-32. doi: 10.1073/pnas.1220601110. Epub 2013 Jan 10. PMID: 23307809 PMCID: PMC3562825 read article


Liu L, Sabo A, Neale BM, Nagaswamy U, Stevens C, Lim E, Bodea CA, Muzny D, Reid JG, Banks E, Coon H, Depristo M, Dinh H, Fennel T, Flannick J, Gabriel S, Garimella K, Gross S, Hawes A, Lewis L, Makarov V, Maguire J, Newsham I, Poplin R, Ripke S, Shakir K, Samocha KE, Wu Y, Boerwinkle E, Buxbaum JD, Cook EH Jr, Devlin B, Schellenberg GD, Sutcliffe JS, Daly MJ, Gibbs RA, Roeder K. Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls. PLoS Genet. 2013 Apr;9(4):e1003443. doi: 10.1371/journal.pgen.1003443. Epub 2013 Apr 11. PMID: 23593035 PMCID: PMC3623759 read article


Verzi MP, Shin H, San Roman AK, Liu XS, Shivdasani RA. Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding. Mol Cell Biol. 2013 Jan;33(2):281-92. doi: 10.1128/MCB.01185-12. Epub 2012 Nov 5. PMID: 23129810 PMCID: PMC3554120 read article


Sarkar A, Hochedlinger K. The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. Cell Stem Cell. 2013 Jan 3;12(1):15-30. doi: 10.1016/j.stem.2012.12.007. PMID: 23290134 PMCID: PMC3608206 read article


Beier KT, Saunders AB, Oldenburg IA, Sabatini BL, Cepko CL. Vesicular stomatitis virus with the rabies virus glycoprotein directs retrograde transsynaptic transport among neurons in vivo. Front Neural Circuits. 2013 Feb 7;7:11. doi: 10.3389/fncir.2013.00011. eCollection 2013. PMID: 23403489 PMCID: PMC3566411 read article


Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 5;155(6):1282-95. doi: 10.1016/j.cell.2013.10.054. PMID: 24315098 PMCID: PMC3894749


Shao DD, Tsherniak A, Gopal S, Weir BA, Tamayo P, Stransky N, Schumacher SE, Zack TI, Beroukhim R, Garraway LA, Margolin AA, Root DE, Hahn WC, Mesirov JP. ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens. Genome Res. 2013 Apr;23(4):665-78. doi: 10.1101/gr.143586.112. Epub 2012 Dec 26. PMID: 23269662 PMCID: PMC3613583 read article


Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC. Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors. Cell. 2013 Nov 7;155(4):844-57. doi: 10.1016/j.cell.2013.09.057. PMID: 24209622


Sitrin J, Ring A, Garcia KC, Benoist C, Mathis D. Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2. J Exp Med. 2013 Jun 3;210(6):1153-65. doi: 10.1084/jem.20122248. Epub 2013 May 6. PMID: 23650440 PMCID: PMC3674700 read article


Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, Sette A, Carrington M, Streeck H. Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control. PMID: 23793098


Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstråle M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S, Chan LF, Clark AJ, Farooqi IS, Majzoub JA. Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science. 2013 Jul 19;341(6143):275-8. doi: 10.1126/science.1233000. PMID: 23869016 PMCID: PMC3788688 read article


He J, Sun E, Bujny MV, Kim D, Davidson MW, Zhuang X. Dual Function of CD81 in Influenza Virus Uncoating and Budding. PLoS Pathog. 2013;9(10):e1003701. doi: 10.1371/journal.ppat.1003701. Epub 2013 Oct 10. PMID: 24130495 PMCID:PMC3795033 read article


Sun E, He J, Zhuang X. Dissecting the role of COPI complexes on influenza virus infection. J Virol. 2013 Mar;87(5):2673-85. doi: 10.1128/JVI.02277-12. Epub 2012 Dec 19. PMID: 23255804 PMCID: PMC3571408 read article


E. Sun, J. He, X. Zhuang. Live cell imaging of viral entry. Curr Opin Virol. 2013 Feb;3(1):34-43. doi: 10.1016/j.coviro.2013.01.005. Epub 2013 Feb 7. Review. PMID: 23395264 PMCID: PMC3587724 read article


Vaughan JC, Dempsey GT, Sun E, Zhuang X. Phosphine-quenching of cyanine dyes as a versatile tool for fluorescent microscopy. J Am Chem Soc. 2013 Jan 30;135(4):1197-200. doi: 10.1021/ja3105279. Epub 2013 Jan 17. PMID: 23311875 PMCID: PMC3624894 read article


Tabebordbar M, Wang ET, Wagers AJ. Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair. Annu Rev Pathol. 2013 Jan 24;8:441-75. doi: 10.1146/annurev-pathol-011811-132450. Epub 2012 Nov 1. PMID: 23121053


Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell. 2013 Nov 7;155(4):909-21. doi: 10.1016/j.cell.2013.10.023. PMID: 24209627 PMCID: PMC3902670


Tan MK, Lim HJ, Bennett EJ, Shi Y, Harper JW. Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. Mol Cell. 2013 Oct 10;52(1):9-24. doi: 10.1016/j.molcel.2013.08.018. Epub 2013 Sep 12. PMID: 24035498 PMCID: PMC3981468


Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y. The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Mol Cell Biol. 2013 Nov;33(21):4166-80. doi: 10.1128/MCB.00689-13. Epub 2013 Aug 26. PMID: 23979597 PMCID: PMC3811896 read article


Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 2013 Dec 5;155(6):1282-95. doi: 10.1016/j.cell.2013.10.054. PMID: 24315098 PMCID: PMC3894749


Tang JC, Szikra T, Kozorovitskiy Y, Teixiera M, Sabatini BL, Roska B, Cepko CL. A nanobody-based system using fluorescent proteins as scaffolds for cell-specific gene manipulation. Cell. 2013 Aug 15;154(4):928-39. doi: 10.1016/j.cell.2013.07.021. PMID: 23953120


Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, Moreau Y, Marshall J, Ramakrishna M, Tarpey P, Shlien A, Whitmore I, Gamble S, Latimer C, Langdon E, Kaufman C, Dovey M, Taylor A, Menzies A, McLaren S, O'Meara S, Butler A, Teague J, Lister J, Chin L, Campbell P, Adams DJ, Zon LI, Patton EE, Stemple DL, Futreal PA. The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biol. 2013;14(10):R113. PMID: 24148783


Choi S, Chatzigeorgiou M, Taylor KP, Schafer WR, Kaplan JM. Analysis of NPR-1 reveals a circuit mechanism for behavioral quiescence in C. elegans. Neuron. 2013 Jun 5;78(5):869-80. doi: 10.1016/j.neuron.2013.04.002. PMID: 23764289 PMCID: PMC3683153


Hull CA, Chu Y, Thanawala M, Regehr WG. Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. J Neurosci. 2013 Apr 3;33(14):5895-902. doi: 10.1523/JNEUROSCI.4052-12.2013. PMID: 23554471 PMCID: PMC3641191 read article


Thanawala MS, Regehr WG. Presynaptic calcium influx controls neurotransmitter release in part by regulating the effective size of the readily releasable pool. J Neurosci. 2013 Mar 13;33(11):4625-33. doi: 10.1523/JNEUROSCI.4031-12.2013. PMID: 23486937 PMCID: PMC3711668 read article


Thomas MP, Lieberman J. Live or let die: posttranscriptional gene regulation in cell stress and cell death. Immunol Rev. 2013 May;253(1):237-52. doi: 10.1111/imr.12052. PMID: 23550650


Eshel N, Tian J, Uchida N. Opening the black box: dopamine, predictions, and learning. Trends Cogn Sci. 2013 Sep;17(9):430-1. doi: 10.1016/j.tics.2013.06.010. Epub 2013 Jul 3. PMID: 23830895 PMCID: PMC3811049


Shyh-Chang N1, Zhu H, Yvanka de Soysa T, Shinoda G, Seligson MT, Tsanov KM, Nguyen L, Asara JM, Cantley LC, Daley GQ. Lin28 enhances tissue repair by reprogramming cellular metabolism. Cell. 2013 Nov 7;155(4):778-92. doi: 10.1016/j.cell.2013.09.059. PMID: 24209617 PMCID: PMC3917449


Tseng WA, Thein T, Kinnunen K, Lashkari K, Gregory MS, D'Amore PA, Ksander BR. NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):110-20. doi: 10.1167/iovs.12-10655. PMID: 23221073 PMCID: PMC3544415 read article


Xu J, Bauer DE, Kerenyi MA, Vo TD, Hou S, Hsu YJ, Yao H, Trowbridge JJ, Mandel G, Orkin SH. Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6518-23. doi: 10.1073/pnas.1303976110. Epub 2013 Apr 1. PMID: 23576758 PMCID: PMC3631619 read article


Zack TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G, Tabak B, Lawrence MS, Zhang CZ, Wala J, Mermel CH, Sougnez C, Gabriel SB, Hernandez B, Shen H, Laird PW, Getz G, Meyerson M, Beroukhim R. Pan-cancer patterns of somatic copy number alteration. Nat Genet. 2013 Sep 26;45(10):1134-1140. doi: 10.1038/ng.2760. [Epub ahead of print] PMID: 24071852 PMCID: PMC3966983


Wang SR, Carmichael H, Andrew SF, Miller TC, Moon JE, Derr MA, Hwa V, Hirschhorn JN, Dauber A. Large-scale pooled next-generation sequencing of 1077 genes to identify genetic causes of short stature. J Clin Endocrinol Metab. 2013 Aug;98(8):E1428-37. doi: 10.1210/jc.2013-1534. Epub 2013 Jun 14. PMID: 23771920 PMCID: PMC3733853


Woodruff MC, Herndon CN, Heesters BA, Carroll MC. Contextual analysis of immunological response through whole-organ fluorescent imaging. Lymphat Res Biol. 2013 Sep;11(3):121-7. doi: 10.1089/lrb.2013.0011. PMID: 24044754 PMCID: PMC3780310


Yamada-Hanff J, Bean BP. Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation. J Neurosci. 2013 Sep 18;33(38):15011-21. doi: 10.1523/JNEUROSCI.0577-13.2013. PMID: 24048831 PMCID: PMC3776055 read article


Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. Nucleic Acids Res. 2013 Oct;41(19):9049-61. doi: 10.1093/nar/gkt555. Epub 2013 Jul 31. PMID: 23907390 PMCID: PMC3799423 read article


Walker SR, Nelson EA, Yeh JE, Pinello L, Yuan GC, Frank DA. STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6. Mol Cell Biol. 2013 Aug;33(15):2879-90. doi: 10.1128/MCB.01620-12. Epub 2013 May 28. PMID: 23716595 PMCID: PMC3719667 read article


Yeh JE, Toniolo P2, Frank DA. JAK2-STAT5 signaling: A novel mechanism of resistance to targeted PI3K/mTOR inhibition. JAKSTAT. 2013 Oct 1;2(4):e24635. doi: 10.4161/jkst.24635. Epub 2013 Apr 15. PMID: 24470973 PMCID: PMC3891630 read article


Yeh JE, Toniolo PA, Frank DA. Targeting transcription factors: promising new strategies for cancer therapy. Curr Opin Oncol. 2013 Nov;25(6):652-8. doi: 10.1097/01.cco.0000432528.88101.1a. PMID: 24048019


Yu Y, Munger K. Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis. Virology. 2013 Nov;446(1-2):251-9. doi: 10.1016/j.virol.2013.08.013. Epub 2013 Sep 5. PMID: 24074588 PMCID: PMC3799973


Cezairliyan B, Vinayavekhin N, Grenfell-Lee D, Yuen GJ, Saghatelian A, Ausubel FM. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans. PLoS Pathog. 2013 Jan;9(1):e1003101. doi: 10.1371/journal.ppat.1003101. Epub 2013 Jan 3. PMID: 23300454 PMCID: PMC3536714


Yung A, Goodrich LV. How to survive a nerve-wracking journey. Elife. 2013 Dec 17;2:e01845. doi: 10.7554/eLife.01845. PMID: 24347551 PMCID: PMC3865645 read article


top

2012


Roberts KA, Abraira VE, Tucker AF, Goodrich LV, Andrews NC. Mutation of rubie, a novel long non-coding RNA located upstream of bmp4, causes vestibular malformation in mice. PLoS One. 2012;7(1):e29495. Epub 2012 Jan 12. PubMed PMID: 22253730; PubMed Central PMCID: PMC3257225.


Adamson B, Smogorzewska A, Sigoillot FD, King RW, Elledge SJ. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol. 2012 Feb 19;14(3):318-28. doi: 10.1038/ncb2426. PMID: 22344029 PMCID: PMC3290715 read article


Sigoillot FD, Lyman S, Huckins JF, Adamson B, Chung E, Quattrochi B, King RW. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. Nat Methods. 2012 Feb 19;9(4):363-6. doi: 10.1038/nmeth.1898. PMID: 22343343 PMCID: PMC3482495 read article


Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ. Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress. Mol Cell. 2012 Aug 10;47(3):396-409. doi: 10.1016/j.molcel.2012.05.024. Epub 2012 Jun 14. PMID: 22704558 PMCID: PMC3613862 read article


Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, Haynes KA, Viel A, Brenner TJ, Church GM, Shah JV, Silver PA. A BioBrick compatible strategy for genetic modification of plants. J Biol Eng. 2012 Jun 20;6(1):8. doi: 10.1186/1754-1611-6-8. PMID: 22716313 PMCID: PMC3537565 read article


Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C. SAP expression in invariant NKT cells is requisite for cognate help and dispensable for non-cognate support to B cells. Blood. 2012 May 21. [Epub ahead of print] PMID: 22613797


Kim HY, Chang YJ, Subramanian S, Lee HH, Albacker LA, Matangkasombut P, Savage PB, McKenzie AN, Smith DE, Rottman JB, DeKruyff RH, Umetsu DT. Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity. J Allergy Clin Immunol. 2012 Jan;129(1):216-27.e1-6. doi: 10.1016/j.jaci.2011.10.036. Epub 2011 Nov 25. PMID: 22119406 PMCID: PMC3246069 read article


Varadarajan N, Kwon DS, Law KM, Ogunniyi AO, Anahtar MN, Richter JM, Walker BD, Love JC. Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3885-90. Epub 2012 Feb 21. PMID:22355106 PMCID: PMC3309713 read article


Astarita JL, Acton SE, Turley SJ. 2012. Podoplanin: emerging functions in development, the immune system, and cancer. Front Immunol. 2012 Sep 12;3:283. doi: 10.3389/fimmu.2012.00283. eCollection 2012. PMID: 22988448 PMCID: PMC3439854 read article


Acton SE*, Astarita JL*, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, Chang J, Peters A, Woodruff M, Kim YA, Swat W, Morita T, Kuchroo V, Carroll MC, Kahn ML, Wucherpfennig KW, Turley SJ. 2012. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity. Immunity. 2012 Aug 24;37(2):276-89. doi: 10.1016/j.immuni.2012.05.022. Epub 2012 Aug 9. PMID 22884313 PMCID: PMC3556784 *co-first authors read article


Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ; Immunological Genome Project Consortium. 2012. Nat Immunol. 2012. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol. 2012 Apr 1;13(5):499-510. doi: 10.1038/ni.2262. PMID:22466668 PMCID: PMC3366863 read article


Dulak AM, Schumacher SE, van Lieshout J, Imamura Y, Fox C, Shim B, Ramos AH, Saksena G, Baca SC, Baselga J, Tabernero J, Barretina J, Enzinger PC, Corso G, Roviello F, Lin L, Bandla S, Luketich JD, Pennathur A, Meyerson M, Ogino S, Shivdasani RA, Beer DG, Godfrey TE, Beroukhim R, Bass AJ. Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res. 2012 Sep 1;72(17):4383-93. Epub 2012 Jul 2. PMID: 22751462 PMCID: PMC3432726 read article


Baca SC, Garraway LA. The genomic landscape of prostate cancer. Front Endocrinol (Lausanne). 2012 May 16;3:69. doi: 10.3389/fendo.2012.00069. eCollection 2012. PMID: 22649426 PMCID: PMC3355898 read article


Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL. Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7882-7. Epub 2012 Apr 27. PubMed PMID: 22543161; PubMed Central PMCID: PMC3356608.


Beliveau BJ, Joyce EF, Apostolopoulos N, Yilmaz F, Fonseka CY, McCole RB, Chang Y, Li JB, Senaratne TN, Williams BR, Rouillard JM, Wu CT. Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21301-6. doi: 10.1073/pnas.1213818110. Epub 2012 Dec 11. PMID: 23236188 PMCID: PMC3535588 read article


Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL, Adelmant G, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J, Marto JA, Hill DE, Cusick ME, Vidal M, Florens L, Washburn MP, Litovchick L, DeCaprio JA. Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog. 2012;8(10):e1002949. doi: 10.1371/journal.ppat.1002949. Epub 2012 Oct 18. PMID:23093934 PMCID:PMC3475652 read article


Boboila C, Alt FW, Schwer B. Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks. Adv Immunol. 2012;116:1-49. doi: 10.1016/B978-0-12-394300-2.00001-6. PMID: 23063072


Boboila C, Oksenych V, Gostissa M, Wang JH, Zha S, Zhang Y, Chai H, Lee CS, Jankovic M, Saez LM, Nussenzweig MC, McKinnon PJ, Alt FW, Schwer B. Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1). Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2473-8. doi: 10.1073/pnas.1121470109. Epub 2012 Jan 30. PMID: 22308491 PMCID: PMC3289296 read article


Martin CJ, Booty MG, Rosebrock TR, Nunes-Alves C, Desjardins DM, Keren I, Fortune SM, Remold HG, Behar SM. Efferocytosis is an innate antibacterial mechanism. Cell Host Microbe. 2012 Sep 13;12(3):289-300. doi: 10.1016/j.chom.2012.06.010. PMID: 22980326; PMCID: PMC3517204 read article


Bowen ME, Henke K, Siegfried KR, Warman ML, Harris MP. (2012) Efficient mapping and cloning of mutations in zebrafish by low-coverage whole-genome sequencing. Genetics 190(3):1017-24. PMCID:PMC3296239.


Kurek KC, Luks VL, Ayturk UM, Alomari AI, Fishman SJ, Spencer SA, Mulliken JB, Bowen ME, Yamamoto GL, Kozakewich HP, Warman ML. (2012) Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum Genet 90(6):1108-15. PMCID:PMC3370283.


Boyle PM, Silver PA. Parts plus pipes: synthetic biology approaches to metabolic engineering. Metab Eng. 2012 May;14(3):223-32. doi: 10.1016/j.ymben.2011.10.003. Epub 2011 Oct 25. PMID: 22037345 PMCID: PMC3293987 read article


Agapakis CM, Boyle PM, Silver PA. Natural strategies for the spatial optimization of metabolism in synthetic biology. Nat Chem Biol. 2012 May 17;8(6):527-35. doi: 10.1038/nchembio.975. PMID: 22596204


Ray, R.S., Corcoran, A.E., Brust, R.B., Nattie, E., Dymecki, S.M. Egr2-neurons control the adult respiratory response to hypercapnia. Brain Res. 2013 May 20;1511:115-25. doi: 10.1016/j.brainres.2012.12.017. Epub 2012 Dec 19. PMID: 23261662 PMCID: PMC3947592


Engleka, K., Manderfield, L., Brust, R.B., Lu, M.M., Dymecki, S.M., and Epstein J.A. Islet1 Derivatives in the Heart are of Both Neural Crest and Second Heard Field Origin. Circ Res. 2012 Mar 30;110(7):922-6. doi: 10.1161/CIRCRESAHA.112.266510. Epub 2012 Mar 6. PMID: 22394517 PMCID: PMC3355870 read article


Burrill DR, Inniss MC, Boyle PM, Silver PA. Synthetic memory circuits for tracking human cell fate. Genes Dev. 2012 Jul 1;26(13):1486-97. doi: 10.1101/gad.189035.112. PMID: 22751502 PMCID: PMC3403016 read article


Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, Haynes KA, Viel A, Brenner TJ, Church GM, Shah JV, Silver PA. A BioBrick compatible strategy for genetic modification of plants. J Biol Eng. 2012 Jun 20;6(1):8. doi: 10.1186/1754-1611-6-8. PMID: 22716313 PMCID: PMC3537565 read article


Cooney JD; Hildick-Smith GJ; Shafizadeh E; McBride PF; Carroll KJ; Anderson H; Shaw GC; Tamplin OK; Branco DS; Dalton AJ; Shah DI; Wong C; Gallagher PG; Zon LI; North TE; Paw, BH. Teleost growth factor idendependence (gfi) genes differentially regulate successive waves of hematopoiesis. Dev Biol. 2013 Jan 15;373(2):431-41. doi: 10.1016/j.ydbio.2012.08.015. Epub 2012 Aug 29. PMID: 22960038 PMCID: PMC3532562 read article


Cedeno-Laurent F, Dimitroff CJ. Galectin-1 research in T cell immunity: past, present and future. Clin Immunol. 2012 Feb;142(2):107-16. doi: 10.1016/j.clim.2011.09.011. Epub 2011 Oct 6. PMID: 22019770 PMCID: PMC3266984 read article


Cedeno-Laurent F, Opperman MJ, Barthel SR, Hays D, Schatton T, Zhan Q, He X, Matta KL, Supko JG, Frank MH, Murphy GF, Dimitroff CJ. Metabolic inhibition of galectin-1-binding carbohydrates accentuates antitumor immunity. J Invest Dermatol. 2012 Feb;132(2):410-20. doi: 10.1038/jid.2011.335. Epub 2011 Dec 8. PMID: 22158550 PMCID: PMC3258338  read article


Cedeno-Laurent F, Dimitroff CJ. Galectins and their ligands: negative regulators of anti-tumor immunity. Glycoconj J. 2012 Dec;29(8-9):619-25. doi: 10.1007/s10719-012-9379-0. Epub 2012 Apr 29. PMID: 22544342 PMCID: PMC3410977 read article


Cedeno-Laurent F, Opperman M, Barthel SR, Kuchroo VK, Dimitroff CJ. Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression. J Immunol. 2012 Apr 1;188(7):3127-37. doi: 10.4049/jimmunol.1103433. Epub 2012 Feb 17. PMID: 22345665 PMCID: PMC3311782 read article


Cedeno-Laurent F, Watanabe R, Teague JE, Kupper TS, Clark RA, Dimitroff CJ. Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma. Blood. 2012 Apr 12;119(15):3534-8. doi: 10.1182/blood-2011-12-396457. Epub 2012 Mar 1. PMID: 22383798 PMCID: PMC3325040 read article


Cedeno-Laurent F, Dimitroff CJ. Evidence of a novel galectin-9-binding membrane glycoprotein ligand on T helper cells. Clin Immunol. 2012 Apr;143(1):6-7. doi: 10.1016/j.clim.2012.01.010. Epub 2012 Jan 24. PMID: 22321867


Chambers AR, Hancock KE, Maison SF, Liberman MC, Polley DB. Sound-Evoked Olivocochlear Activation in Unanesthetized Mice. J Assoc Res Otolaryngol. 2012 Apr;13(2):209-17. doi: 10.1007/s10162-011-0306-z. Epub 2011 Dec 13. PMID: 22160753 PMCID: PMC3298614 read article


Chan YK, Huang IC, Farzan M. IFITM proteins restrict antibody-dependent enhancement of dengue virus infection. PLoS One. 2012;7(3):e34508. doi: 10.1371/journal.pone.0034508. Epub 2012 Mar 30. PMID: 22479637; PMCID: PMC3316688.  read article


Lui JC, Nilsson O, Chan Y, Palmer CD, Andrade AC, Hirschhorn JN, Baron J. Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height. Hum Mol Genet. 2012 Dec 1;21(23):5193-201. doi: 10.1093/hmg/dds347. Epub 2012 Aug 21. PMID: 22914739 PMCID: PMC3490510 read article


Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L,Reynoso ED, Gonzalez SF, Graham DB, Chang J, Peters A, Woodruff M, Kim YA, Swat W, Morita T, Kuchroo V, Carroll MC, Kahn ML, Wucherpfennig KW,Turley SJ. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity. 2012 Aug 24;37(2):276-89. doi: 10.1016/j.immuni.2012.05.022. Epub 2012 Aug 9. PMID: 22884313 PMCID: PMC3556784 read article


Cherry AB, Daley GQ. Reprogramming cellular identity for regenerative medicine. Cell. 2012 Mar 16;148(6):1110-22. doi: 10.1016/j.cell.2012.02.031. PMID: 22424223; PMCID: PMC3354575.  read article


Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, Meldrim J, Ram O, Cheng C, Gnirke A, Fisher S, Friedman N, Wong B, Bernstein BE, Nusbaum C, Hacohen N, Regev A, Amit I. A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Mol Cell. 2012 Sep 14;47(5):810-22. doi: 10.1016/j.molcel.2012.07.030. Epub 2012 Aug 30. PMID: 22940246 PMCID: PMC3873101 read article


Moseman EA, Iannacone M, Bosurgi L, Tonti E, Chevrier N, Tumanov A, Fu YX, Hacohen N, von Andrian UH. B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity. 2012 Mar 23;36(3):415-26. doi: 10.1016/j.immuni.2012.01.013. Epub 2012 Mar 1. PMID: 22386268 PMCID: PMC3359130 read article


Shalek AK, Gaublomme JT, Wang L, Yosef N, Chevrier N, Andersen MS, Robinson JT, Pochet N, Neuberg D, Gertner RS, Amit I, Brown JR, Hacohen N, Regev A, Wu CJ, Park H. Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia. Nano Lett. 2012 Dec 12;12(12):6498-504. doi: 10.1021/nl3042917. Epub 2012 Dec 3. PMID: 23190424 PMCID: PMC3573729 read article


Chiang CW, Liu CT, Lettre G, Lange LA, Jorgensen NW, Keating BJ, Vedantam S, Nock NL, Franceschini N, Reiner AP, Demerath EW, Boerwinkle E, Rotter JI, Wilson JG, North KE, Papanicolaou GJ, Cupples LA, Murabito JM, Consortium G, Hirschhorn JN. Ultraconserved Elements in the Human Genome: Association and Transmission Analyses of Highly Constrained SNPs. Genetics. 2012 Jun 19. [Epub ahead of print] PubMed PMID: 22714408.


Choi EY, Yeo BT, Buckner RL. The organization of the human striatum estimated by intrinsic functional connectivity. J Neurophysiol. 2012 Oct;108(8):2242-63. doi: 10.1152/jn.00270.2012. Epub 2012 Jul 25. PMID: 22832566. PMCID:PMC3545026.


Stadtfeld, M., Apostolou, E., Ferrari, F., Choi, J., Walsh, R.M., Chen, T., Oi, S., Kim, S.Y., Bestor, T., Shioda, T., et al. (2012). Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet. 2012 Mar 4;44(4):398-405, S1-2. doi: 10.1038/ng.1110. PMID: 22387999 PMCID: PMC3538378 read article


He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT. Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15. Epub 2011 Dec 8. PubMed PMID: 22158708; PubMed Central PMCID: PMC3282145.


Chu Y, Fioravante D, Thanawala M, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. J Neurosci. 2012 Oct 3;32(40):13796-804. doi: 10.1523/JNEUROSCI.2158-12.2012. PMID: 23035091 PMCID: PMC3626456 read article


Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature. 2012 Aug 30;488(7413):647-51. doi: 10.1038/nature11310. PMID: 22763451 PMCID: PMC3615424 read article


Xu Y, Xu C, Kato A, Tempel W, Abreu JG, Bian C, Hu Y, Hu D, Zhao B, Cerovina T, Diao J, Wu F, He HH, Cui Q, Clark E, Ma C, Barbara A, Veenstra GJ, Xu G, Kaiser UB, Liu XS, Sugrue SP, He X, Min J, Kato Y, Shi YG. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell. 2012 Dec 7;151(6):1200-13. doi: 10.1016/j.cell.2012.11.014. PMID: 23217707 PMCID: PMC3705565 read article


Narayan K, Sylvia KE, Malhotra N, Yin CC, Martens G, Vallerskog T, Kornfeld H, Xiong N, Cohen NR, Brenner MB, Berg LJ, Kang J; Immunological Genome Project Consortium. Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. Nat Immunol. 2012 Apr 1;13(5):511-8. doi: 10.1038/ni.2247. PMID: 22473038 PMCID: PMC3427768


Cohen NA, Stewart ML, Gavathiotis E, Tepper JL, Bruekner SR, Koss B, Opferman JT, Walensky LD. A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival. Chem Biol. 2012 Sep 21;19(9):1175-86. doi: 10.1016/j.chembiol.2012.07.018. PMID: 22999885 PMCID: PMC3582387 read article


Wang HH, Kim H, Cong L, Jeong J, Bang D, Church GM. Genome-scale promoter engineering by coselection MAGE. Nat Methods. 2012 Jun;9(6):591-3. doi: 10.1038/nmeth.1971. Epub 2012 Apr 8. PubMed PMID: 22484848 PMCID: PMC3428217 read article


Folco EG, Lee CS, Dufu K, Yamazaki T, Reed R. The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export. PLoS One. 2012;7(8):e43804. doi: 10.1371/journal.pone.0043804. Epub 2012 Aug 23. PMID: 22928037 PMCID: PMC3426524 read article


Silveira-Neto AP, Leal LF, Emerman AB, Henderson KD, Piskounova E, Henderson BE, Gregory RI, Silveira LF, Hirschhorn JN, Nguyen TT, Beneduzzi D, Tusset C, Reis AC, Brito VN, Mendonca BB, Palmert MR, Antonini SR, Latronico AC. Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty. Horm Res Paediatr. 2012;78(3):144-50. doi: 10.1159/000342212. Epub 2012 Sep 6. PMID: 22964795. PMCID: PMC3526815. read article


Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.Nat Immunol. 2012 Oct;13(10):972-80. doi: 10.1038/ni.2420. Epub 2012 Sep 9.PMID: 22961053. PMCID: PMC3698954


Fassett MS, Jiang W, D'Alise AM, Mathis D, Benoist C Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3891-6. Epub 2012 Feb 15. PMID: 22345564. PMCID: PMC3309794


Finley LW, Lee J, Souza A, Rowe G, Clish CB, Arany Z, Haigis MC. Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction. Proc Natl Acad Sci USA 2012 Feb 3. PMCID: PMC3286952


Ford KM, D'Amore PA. Molecular regulation of vascular endothelial growth factor expression in the retinal pigment epithelium. Mol Vis. 2012;18:519-27. Epub 2012 Mar 1. PMID: 22419845 PMCID: PMC3298425 read article


Ford KM, Saint-Geniez M, Walshe TE, D'Amore PA. Expression and role of VEGF--a in the ciliary body. Invest Ophthalmol Vis Sci. 2012 Nov 7;53(12):7520-7. doi: 10.1167/iovs.12-10098. PMID: 23081980 PMCID: PMC3493183 read article


Clapham KR, Yu TW, Ganesh VS, Barry B, Chan Y, Mei D, Parrini E, Funalot B, Dupuis L, Nezarati MM, du Souich C, van Karnebeek C, Guerrini R, Walsh CA. FLNA genomic rearrangements cause periventricular nodular heterotopia. Neurology. 2012 Jan 24;78(4):269-78. PMID: 22238415. PMCID - PMC Journal in Process


Chiang JJ, Gardner MR, Quinlan BD, Dorfman T, Choe H, Farzan M. Enhanced recognition and neutralization of HIV-1 by antibody-derived CCR5-mimetic peptide variants. J Virol. 2012 Nov;86(22):12417-21. doi: 10.1128/JVI.00967-12. Epub 2012 Aug 29. PMID: 22933279 PMCID: PMC3486504 read article


Barral DC, Garg S, Casalou C, Watts GF, Sandoval JL, Ramalho JS, Hsu VW, Brenner MB. Arl13b regulates endocytic recycling traffic. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21354-9. doi 10.1073/pnas.1218272110. Epub 2012 Dec 7. PMID: 23223633. PMCID: PMC3535586


Garnaas MK, Cutting CC, Meyers A, Kelsey PB Jr, Harris JM, North TE, Goessling W. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol. 2012 Dec 15;372(2):178-89. doi: 10.1016/j.ydbio.2012.09.001. Epub 2012 Sep 13.PMID: 22982668 PMCID: PMC3697125 read article


Pattaro C1, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson Å, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu FB, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Koenig W, Illig T, Döring A, Wichmann HE, Kolcic I, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Endlich K, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Giulianini F, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Metzger M, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman JC, Hayward C, Ridker P, Parsa A, Bochud M, Heid IM, Goessling W, Chasman DI, Kao WH, Fox CS. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012;8(3):e1002584. doi: 10.1371/journal.pgen.1002584. Epub 2012 Mar 29. PMID: 22479191 PMCID: PMC3315455 read article


Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, Beier DR, Goessling W, Sunyaev SR. Mutation mapping and identification by whole-genome sequencing. Genome Res. 2012 Aug;22(8):1541-8. doi: 10.1101/gr.135541.111. Epub 2012 May 3. PMID: 22555591 PMCID: PMC3409267 read article


Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, Lawler J, Wei W. SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. J Exp Med. 2012 Jul 2;209(7):1289-307. doi: 10.1084/jem.20112446. Epub 2012 Jun 18. PMID: 22711876PMCID: PMC3405505 read article


Derr ND1, Goodman BS, Jungmann R, Leschziner AE, Shih WM, Reck-Peterson SL. Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold. Science. 2012 Nov 2;338(6107):662-5. doi: 10.1126/science.1226734. Epub 2012 Oct 11. PMID: 23065903 PMCID: PMC3840815 read article


Goodman BS, Derr ND, Reck-Peterson SL. Engineered, harnessed, and hijacked: synthetic uses for cytoskeletal systems. Trends Cell Biol. 2012 Dec;22(12):644-52. doi: 10.1016/j.tcb.2012.09.005. Epub 2012 Oct 8. PMID: 23059001 PMCID: PMC3505249 read article


Qiu W, Derr ND, Goodman BS, Villa E, Wu D, Shih W, Reck-Peterson SL. Dynein achieves processive motion using both stochastic and coordinated stepping. Nat Struct Mol Biol. 2012 Jan 8;19(2):193-200. doi: 10.1038/nsmb.2205. PMID: 22231401 PMCID: PMC3272163 read article


Chiang WC, Tishkoff DX, Yang B, Wilson-Grady J, Yu X, Mazer T, Eckersdorff M, Gygi SP, Lombard DB, Hsu AL. C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress. PLoS Genet. 2012 Sep;8(9):e1002948. doi: 10.1371/journal.pgen.1002948. Epub 2012 Sep 13. PMID: 23028355 PMCID: PMC3441721 read article


Greenblatt MB, Sargent JL, Farina G, Tsang K, Lafyatis R, Glimcher LH, Whitfield ML, Aliprantis AO. Interspecies Comparison of Human and Murine Scleroderma Reveals IL-13 and CCL2 as Disease Subset-Specific Targets. Am J Pathol. 2012 Mar;180(3):1080-94. Epub 2012 Jan 11. PMID: 22245215. PMCID: PMC3349888


Greenblatt MB, Vbranac V, Tivey T, Tsang K, Tager AM, Aliprantis AO Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model.PLoS One. 2012;7(9):e44664. Epub 2012 Sep 5. PMID:22957096. PMCID: PMC3434179


Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME, Hirschey M, Vaitheesvaran B, Farese RV Jr, Kurland IJ, Graham M, Crooke R, Foufelle F, Biddinger SB. Hepatic Insulin Signaling Is Required for Obesity-Dependent Expression of SREBP-1c mRNA but Not for Feeding-Dependent Expression. Cell Metab. 2012 Jun 6;15(6):873-84. doi: 10.1016/j.cmet.2012.05.002. PMID: 22682225 PMCID: PMC3383842.  read article


Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME. Bhlhb5 and prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303. PubMed PMID: 22284184; PubMed Central PMCID: PMC3269007.


Sung JH, Zhang H, Moseman EA, Alvarez D, Iannacone M, Henrickson SE, de la Torre JC, Groom JR, Luster AD, von Andrian UH. Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes. Cell. 2012 Sep 14;150(6):1249-63. doi: 10.1016/j.cell.2012.08.015. PMID: 22980984. PMCID: PMC3445043.


Holoch D, Moazed D. RNAi in fission yeast finds new targets and new ways of targeting at the nuclear periphery. Genes Dev. 2012 Apr 15;26(8):741-5. doi: 10.1101/gad.191155.112. PMID: 22508721 PMCID: PMC3337448 read article


Houser BL. Decidual macrophages and their roles at the maternal-fetal interface. Yale J Biol Med. 2012 Mar;85(1):105-18. Epub 2012 Mar 29. PMID: 22461749 PMCID: PMC3313525 read article


Blum B, Hrvatin SS, Schuetz C, Bonal C, Rezania A, Melton DA. Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3. Nat Biotechnol. 2012 Feb 26;30(3):261-4. doi: 10.1038/nbt.2141. PubMed PMID: 22371083.


Hu X, Daly M. What have we learned from six years of GWAS in autoimmune diseases, and what is next? Curr Opin Immunol. 2012 Oct;24(5):571-5. doi: 10.1016/j.coi.2012.09.001. Epub 2012 Sep 24. PMID: 23017373


Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H; International IBD Genetics Consortium (IIBDGC), Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582. PMID 23128233 PMCID: PMC3491803 read article


Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium, Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11. PMID: 23143596 PMCID: PMC3605761 read article


Hwang J, Jaroensuk J, Leimanis ML, Russell B, McGready R, Day N, Snounou G, Nosten F, Imwong M. Long-term storage limits PCR-based analyses of malaria parasites in archival dried blood spots. Malar J. 2012 Oct 8;11:339. doi: 10.1186/1475-2875-11-339. PMID: 23043522


Zhang W, Mendoza MC, Pei X, Ilter D, Mahoney SJ, Zhang Y, Ma D, Blenis J, Wang Y. Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling. J Biol Chem. 2012 Apr 6;287(15):11850-8. doi: 10.1074/jbc.M111.258236. Epub 2012 Feb 15. PMID: 22337876 PMCID: PMC3320933 read article


Burrill DR, Inniss MC, Boyle PM, Silver PA. Synthetic memory circuits for tracking human cell fate. Genes Dev. 2012 Jul 1;26(13):1486-97. doi: 10.1101/gad.189035.112. PMID: 22751502 PMCID: PMC3403016 read article


Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, Haynes KA, Viel A, Brenner TJ, Church GM, Shah JV, Silver PA. A BioBrick compatible strategy for genetic modification of plants. J Biol Eng. 2012 Jun 20;6(1):8. doi: 10.1186/1754-1611-6-8. PMID: 22716313 PMCID: PMC3537565 read article


Rajani DK, Walch M, Martinvalet D, Thomas MP, Lieberman J. Alterations in RNA processing during immune-mediated programmed cell death. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8688-93. doi: 10.1073/pnas.1201327109. Epub 2012 May 15. PMID: 22589304 PMCID: PMC3365155 read article


Collins B, Kane EA, Reeves DC, Akabas MH, Blau J. Balance of activity between LN(v)s and glutamatergic dorsal clock neurons promotes robust circadian rhythms in Drosophila. Neuron. 2012 May 24;74(4):706-18. doi: 10.1016/j.neuron.2012.02.034. PMID: 22632728 PMCID: PMC3361687 read article


Gershow M, Berck M, Mathew D, Luo L, Kane EA, Carlson JR, Samuel AD. Controlling airborne cues to study small animal navigation. Nat Methods. 2012 Jan 15;9(3):290-6. doi: 10.1038/nmeth.1853. PMID: 22245808 PMCID: PMC3513333 read article


Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012 Jan 17;21(1):66-81. doi: 10.1016/j.ccr.2011.11.024. PMID: 22264789 PMCID: PMC3999522 read article


Wood KC, Konieczkowski DJ, Johannessen CM, Boehm JS, Tamayo P, Botvinnik OB, Mesirov JP, Hahn WC, Root DE, Garraway LA, Sabatini DM. MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma. Sci Signal. 2012 May 15;5(224):rs4. doi: 10.1126/scisignal.2002612. PMID: 22589389 PMCID: PMC3498828 read article


Kung JT, Gelbart ME. Getting a head start: the importance of personal genetics education in high schools. Yale J Biol Med. 2012 Mar;85(1):87-92. Epub 2012 Mar 29. PMID: 22461746 PMCID: PMC3313542 read article


Penaranda C, Kuswanto W, Hofmann J, Kenefeck R, Narendran P, Walker LS, Bluestone JA, Abbas AK, Dooms H. IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12668-73. doi: 10.1073/pnas.1203692109. Epub 2012 Jun 25. PMID: 22733744 PMCID: PMC3411948 read article


Tukachinsky H, Kuzmickas RP, Jao CY, Liu J, Salic A. Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand. Cell Rep. 2012 Aug 30;2(2):308-20. doi: 10.1016/j.celrep.2012.07.010. Epub 2012 Aug 16. PMID: 22902404 PMCID: PMC3682496 read article


Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N. Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen. ACS Chem Biol. 2012 Jan 20;7(1):185-96. doi: 10.1021/cb200305u. Epub 2011 Oct 21. PMID: 21992004 PMCID: PMC3262907 read article


Butovsky O, Siddiqui S, Gabriely G, Lanser AJ, Dake B, Murugaiyan G, Doykan CE, Wu PM, Gali RR, Iyer LK, Lawson R, Berry J, Krichevsky AM, Cudkowicz ME, Weiner HL. Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. Journal of Clinical Immunology. J Clin Invest. 2012 Sep 4;122(9):3063-87. doi: 10.1172/JCI62636. Epub 2012 Aug 6. PMID: 22863620 PMCID: PMC3428086 read article


Driscoll B, Kikuchi A, Lau AN, Lee J, Reddy R, Jesudason E, Kim CF, Warburton D. Isolation and characterization of distal lung progenitor cells. Methods Mol Biol. 2012;879:109-22. doi: 10.1007/978-1-61779-815-3_7. PMID: 22610556 PMCID: PMC3710291 read article


Lau AN, Goodwin M, Kim CF, Weiss DJ. Stem cells and regenerative medicine in lung biology and diseases. Mol Ther. 2012 Jun;20(6):1116-30. doi: 10.1038/mt.2012.37. Epub 2012 Mar 6. PMID: 22395528 PMCID: PMC3369292 read article


Tropea KA, Leder E, Aslam M, Lau AN, Raiser DM, Lee JH, Balasubramaniam V, Fredenburgh LE, Alex Mitsialis S, Kourembanas S, Kim CF. Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2012 May;302(9):L829-37. doi: 10.1152/ajplung.00347.2011. Epub 2012 Feb 10. PMID: 22328358 PMCID: PMC3362163. read article


Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W Jr, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 5;18(3):396-404. doi: 10.1038/nm.2629. PubMed PMID: 22306733.


Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012 Jan 17;21(1):66-81. PubMed PMID: 22264789.


Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol. 2012 Dec 23;14(2):179-85. doi: 10.1038/ni.2509. Epub 2012 Dec 23. PMID: 23263557


Lee RS, Stewart C, Carter SL, Ambrogio L, Cibulskis K, Sougnez C, Lawrence MS, Auclair D, Mora J, Golub TR, Biegel JA, Getz G, Roberts CW. A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J Clin Invest. 2012 Aug 1;122(8):2983-8. doi: 10.1172/JCI64400. Epub 2012 Jul 17. PMID: 22797305 PMCID:PMC3408754 read article


Landreville S, Agapova OA, Matatall KA, Kneass ZT, Onken MD, Lee RS, Bowcock AM, Harbour JW. Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma. Clin Cancer Res. 2012 Jan 15;18(2):408-16. doi: 10.1158/1078-0432.CCR-11-0946. Epub 2011 Oct 28. PMID: 22038994 PMCID: PMC3261307 read article


Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nat Immunol. 2012 Oct;13(10):991-9. doi: 10.1038/ni.2416. Epub 2012 Sep 9. PMID: 22961052 PMCID: PMC3459594 read article


Schafer DP, Lehrman EK, Kautzman AG, Koyama R, Mardinly AR, Yamasaki R, Ransohoff RM, Greenberg ME, Barres BA, Stevens B. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron. 2012 May 24;74(4):691-705. doi: 10.1016/j.neuron.2012.03.026.PMID: 22632727 PMCID: PMC3528177 read article


León L, Tatituri RV, Grenha R, Sun Y, Barral DC, Minnaard AJ, Bhowruth V, Veerapen N, Besra GS, Kasmar A, Peng W, Moody DB, Grabowski GA, Brenner MB. Saposins utilize two strategies for lipid transfer and CD1 antigen presentation. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4357-64. doi: 10.1073/pnas.1200764109. Epub 2012 Feb 13. PMID: 22331868 PMCID: PMC3311357 read article


Chahrour MH, Yu TW, Lim ET, Ataman B, Coulter ME, Hill RS, Stevens CR, Schubert CR; ARRA Autism Sequencing Collaboration, Greenberg ME, Gabriel SB, Walsh CA. Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism. PLoS Genet. 2012;8(4):e1002635. doi: 10.1371/journal.pgen.1002635. Epub 2012 Apr 12. PMID: 22511880 PMCID: PMC3325173 read article


Staropoli JF, Karaa A, Lim ET, Kirby A, Elbalalesy N, Romansky SG, Leydiker KB, Coppel SH, Barone R, Xin W, MacDonald ME, Abdenur JE, Daly MJ, Sims KB, Cotman SL. A homozygous mutation in KCTD7 links neuronal ceroid lipofuscinosis to the ubiquitin-proteasome system. Am J Hum Genet. 2012 Jul 13;91(1):202-8. doi: 10.1016/j.ajhg.2012.05.023. Epub 2012 Jun 28. PMID: 22748208 PMCID: PMC3397260 read article


Neale BM, Kou Y, Liu L, Ma'ayan A, Samocha KE, Sabo A, Lin CF, Stevens C, Wang LS, Makarov V, Polak P, Yoon S, Maguire J, Crawford EL, Campbell NG, Geller ET, Valladares O, Schafer C, Liu H, Zhao T, Cai G, Lihm J, Dannenfelser R, Jabado O, Peralta Z, Nagaswamy U, Muzny D, Reid JG, Newsham I, Wu Y, Lewis L, Han Y, Voight BF, Lim E, Rossin E, Kirby A, Flannick J, Fromer M, Shakir K, Fennell T, Garimella K, Banks E, Poplin R, Gabriel S, DePristo M, Wimbish JR, Boone BE, Levy SE, Betancur C, Sunyaev S, Boerwinkle E, Buxbaum JD, Cook EH Jr, Devlin B, Gibbs RA, Roeder K, Schellenberg GD, Sutcliffe JS, Daly MJ. Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature. 2012 Apr 4;485(7397):242-5. doi: 10.1038/nature11011. PMID: 22495311 PMCID: PMC3613847 read article


Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV Jr. DGAT1 mutation is linked to a congenital diarrheal disorder. J Clin Invest. 2012 Dec 3;122(12):4680-4. doi: 10.1172/JCI64873. Epub 2012 Nov 1. PMID: 23114594 PMCID: PMC3533555 read article


Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z. Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. Nature. 2012 May 9;485(7398):333-8. doi: 10.1038/nature11040. PMID: 22596155 PMCID: PMC3356917.  read article


Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D'Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE. An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature. 2012 Nov 15;491(7424):449-53. doi: 10.1038/nature11624. Epub 2012 Oct 31. PMID: 23123854 PMCID: PMC3521494 read article


Lohmueller JJ, Armel TZ, Silver PA. A tunable zinc finger-based framework for Boolean logic computation in mammalian cells. Nucleic Acids Res. 2012 Jun;40(11):5180-7. doi: 10.1093/nar/gks142. Epub 2012 Feb 9. PMID: 22323524 PMCID: PMC3367183 read article


Garg A, Lohmueller JJ, Silver PA, Armel TZ. Engineering synthetic TAL effectors with orthogonal target sites. Nucleic Acids Res. 2012 Aug;40(15):7584-95. doi: 10.1093/nar/gks404. Epub 2012 May 11. PMID: 22581776 PMCID: PMC3424557 read article


Liu Y, Belkina NV, Park C, Nambiar R, Loughhead SM, Patino-Lopez G, Ben-Aissa K, Hao JJ, Kruhlak MJ, Qi H, von Andrian UH, Kehrl JH, Tyska MJ, Shaw S. Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Blood. 2012 Jan 12;119(2):445-53. doi: 10.1182/blood-2011-07-368860. Epub 2011 Nov 21. PMID: 22106344 PMCID: PMC3257010 read article


Giménez-Cassina A1, Martínez-François JR, Fisher JK, Szlyk B, Polak K, Wiwczar J, Tanner GR, Lutas A, Yellen G, Danial NN. BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures. Neuron. 2012 May 24;74(4):719-30. doi: 10.1016/j.neuron.2012.03.032. PMID: 22632729 PMCID: PMC3361694


Musselwhite LW, Maciag K, Lankowski A, Gretes MC, Wellems TE, Tavera G, Goulding RE, Guillen E. First Universities Allied for Essential Medicines (UAEM) Neglected Diseases and Innovation Symposium. Am J Trop Med Hyg. 2012 Jan;86(1):65-74. doi: 10.4269/ajtmh.2012.11-0608. PMID: 22232453 PMCID: PMC3247111 read article


Madigan CA, Cheng TY, Layre E, Young DC, McConnell MJ, Debono CA, Murry JP, Wei JR, Barry CE 3rd, Rodriguez GM, Matsunaga I, Rubin EJ, Moody DB. Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1257-62. Epub 2012 Jan 9. PubMed PMID: 22232695; PubMed Central PMCID: PMC3268331.


Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ, Immunological Genome Project Consortium. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol. 2012 Apr 1;13(5):499-510. doi: 10.1038/ni.2262. PMID: 22466668 PMCID: PMC3366863 read article


Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, Chang J, Peters A, Woodruff M, Kim YA, Swat W, Morita T, Kuchroo V, Carroll MC, Kahn ML, Wucherpfennig KW, Turley SJ. Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2. Immunity. 2012 Aug 24;37(2):276-89. doi: 10.1016/j.immuni.2012.05.022. Epub 2012 Aug 9. PMID: 22884313 PMCID: PMC3556784 read article


Wills ZP, Mandel-Brehm C, Mardinly AR, McCord AE, Giger RJ, Greenberg ME.The nogo receptor family restricts synapse number in the developing hippocampus. Neuron. 2012 Feb 9;73(3):466-81. doi: 10.1016/j.neuron.2011.11.029. PMID: 22325200 PMCID: PMC3532882 read article


Majczenko K, Davidson AE, Camelo-Piragua S, Agrawal PB, Manfready RA, Li X, Joshi S, Xu J, Peng W, Beggs AH, Li JZ, Burmeister M, Dowling JJ. Dominant mutation of CCDC78 in a unique congenital myopathy with prominent internal nuclei and atypical cores. Am J Hum Genet. 2012 Aug 10;91(2):365-71. doi: 10.1016/j.ajhg.2012.06.012. Epub 2012 Jul 19. PMID: 22818856 PMCID: PMC3415545 read article


Lawlor MW, Alexander MS, Viola MG, Meng H, Joubert R, Gupta V, Motohashi N, Manfready RA, Hsu CP, Huang P, Buj-Bello A, Kunkel LM, Beggs AH, Gussoni E. Myotubularin-deficient myoblasts display increased apoptosis, delayed proliferation, and poor cell engraftment. Am J Pathol. 2012 Sep;181(3):961-8. doi: 10.1016/j.ajpath.2012.05.016. Epub 2012 Jul 27. PMID: 22841819 PMCID PMC3432426 read article


Thomas GM, Carbo C, Curtis BR, Martinod K, Mazo IB, Schatzberg D, Cifuni SM, Fuchs TA, von Andrian UH, Hartwig JH, Aster RH, Wagner DD. Extracellular DNA traps are associated with pathogenesis of TRALI in humans and mice. Blood. 2012 Jun 28;119(26):6335-43. doi: 10.1182/blood-2012-01-405183. Epub 2012 May 17. PMID: 22596262 PMCID: PMC3383196 read article


Brill A, Fuchs TA, Savchenko AS, Thomas GM, Martinod K, De Meyer SF, Bhandari AA, Wagner DD. Neutrophil extracellular traps promote deep vein thrombosis in mice. J Thromb Haemost. 2012 Jan;10(1):136-44. doi: 10.1111/j.1538-7836.2011.04544.x. PMID: 22044575 PMCID: PMC3319651 read article


Demers M, Krause DS, Schatzberg D, Martinod K, Voorhees JR, Fuchs TA, Scadden DT, Wagner DD. Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis. Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13076-81. doi: 10.1073/pnas.1200419109. Epub 2012 Jul 23. PMID: 22826226 PMCID: PMC3420209 read article


Chen K, Nishi H, Travers R, Tsuboi N, Martinod K, Wagner DD, Stan R, Croce K, Mayadas TN. Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo. Blood. 2012 Nov 22;120(22):4421-31. doi: 10.1182/blood-2011-12-401133. Epub 2012 Sep 6. PMID: 22955924 PMCID: PMC3507149 read article


Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. Cell Stem Cell. 2012 Sep 7;11(3):359-72. Epub 2012 Aug 2. PMID:22863534; NIHMS: NIHMS572904


Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D'Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE. An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature. 2012 Nov 15;491(7424):449-53. doi: 10.1038/nature11624. Epub 2012 Oct 31. PMID: 23123854 PMCID: PMC3521494 read article


Osmundson J, Montero-Diez C, Westblade LF, Hochschild A, Darst SA. Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell. 2012 Nov 21;151(5):1005-16. doi: 10.1016/j.cell.2012.10.034. PMID: 23178120 PMCID: PMC3604623 read article


Pillai S, Netravali IA, Cariappa A, and Mattoo H. Siglecs and immune regulation. Annu Rev Immunol. 2012;30:357-92. doi: 10.1146/annurev-immunol-020711-075018. Epub 2012 Jan 3. PMID: 22224769 PMCID: PMC3781015 read article


Ng MR, Besser A, Danuser G, Brugge JS. Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility. J Cell Biol. 2012 Oct 29;199(3):545-63. doi: 10.1083/jcb.201207148. Epub 2012 Oct 22. PMID: 23091067 PMCID: PMC3483134 read article


Ni AM, Ray S, Maunsell JH. Tuned normalization explains the size of attention modulations. Neuron. 2012 Feb 23;73(4):803-13. PubMed PMID: 22365552; PubMed Central PMCID: PMC3292773.


Nugent AA, Kolpak AL, Engle EC. Human disorders of axon guidance. Curr Opin Neurobiol. 2012 Oct;22(5):837-43. doi: 10.1016/j.conb.2012.02.006. Epub 2012 Mar 5. PMID: 22398400 PMCID: PMC3388149  read article


Gondek DC, Olive AJ, Stary G, Starnbach MN. CD4+ T cells are necessary and sufficient to confer protection against Chlamydia trachomatis infection in the murine upper genital tract. J Immunol. 2012 Sep 1;189(5):2441-9. doi: 10.4049/jimmunol.1103032. Epub 2012 Aug 1. PMID: 22855710 PMCID: PMC3690950 read article


Rosmarin DM, Carette JE, Olive AJ, Starnbach MN, Brummelkamp TR, Ploegh HL. Attachment of Chlamydia trachomatis L2 to host cells requires sulfation. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10059-64. doi: 10.1073/pnas.1120244109. Epub 2012 Jun 6. PMID: 22675117 PMCID: PMC3382535 read article


Otchy TM, Ölveczky BP. Design and assembly of an ultra-light motorized microdrive for chronic neural recordings in small animals. J Vis Exp. 2012 Nov 8;(69). pii: 4314. doi: 10.3791/4314. PMID: 23169237 PMCID: PMC3520581 read article


Martínez-Noël G, Galligan JT, Sowa ME, Arndt V, Overton TM, Harper JW, Howley PM. Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Mol Cell Biol. 2012 Aug;32(15):3095-106. doi: 10.1128/MCB.00201-12. Epub 2012 May 29. PMID: 22645313 PMCID: PMC3434508 read article


Matreyek KA, Oztop I, Freed EO, Engelman A. Viral latency and potential eradication of HIV-1. Expert Rev Anti Infect Ther. 2012 Aug;10(8):855-7. doi: 10.1586/eri.12.68. PMID: 23030323 PMCID: PMC3573755 read article


Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN. Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection. J Virol. 2012 Apr;86(8):4708-14. doi: 10.1128/JVI.05887-11. Epub 2012 Feb 1. PMID: 22301145 PMCID: PMC3318671 read article


Wesemann DR, Portuguese AJ, Magee JM, Gallagher MP, Zhou X, Panchakshari RA, Alt FW. Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13745-50. doi: 10.1073/pnas.1210286109. Epub 2012 Aug 6. PMID: 22869756 PMCID: PMC3427115  read article


Larman HB, Xu GJ, Pavlova NN, Elledge SJ. Construction of a rationally designed antibody platform for sequencing-assisted selection. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18523-8. doi: 10.1073/pnas.1215549109. Epub 2012 Oct 11. PMID: 23064642 PMCID: PMC3494914 read article


Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L. A landscape of driver mutations in melanoma. Cell. 2012 Jul 20;150(2):251-63. doi: 10.1016/j.cell.2012.06.024. PMID: 22817889 PMCID: PMC3600117 read article


Puram SV, Yeung CM, Jahani-Asl A, Lin C, de la Iglesia N, Konopka G, Jackson-Grusby L, Bonni A. STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation. J Neurosci. 2012 Jun 6;32(23):7806-18. doi: 10.1523/JNEUROSCI.3243-11.2012. PMID: 22674257 PMCID: PMC3409246 read article


Blackburn JS, Liu S, Raiser DM, Martinez SA, Feng H, Meeker ND, Gentry J, Neuberg D, Look AT, Ramaswamy S, Bernards A, Trede NS, Langenau DM. Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency. Leukemia. 2012 Sep;26(9):2069-78. doi: 10.1038/leu.2012.116. Epub 2012 Apr 27. PMID: 22538478 PMCID: PMC3435461 read article


Tropea KA, Leder E, Aslam M, Lau AN, Raiser DM, Lee JH, Balasubramaniam V, Fredenburgh LE, Alex Mitsialis S, Kourembanas S, Kim CF. Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2012 May 1;302(9):L829-37. doi: 10.1152/ajplung.00347.2011. Epub 2012 Feb 10. PMID: 22328358 PMCID: PMC3362163 read article


Moore FE, Reyon D, Sander JD, Martinez SA, Blackburn JS, Khayter C, Ramirez CL, Joung JK, Langenau DM. Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs). PLoS One. 2012;7(5):e37877. Epub 2012 May 24. PubMed PMID: 22655075; PubMed Central PMCID: PMC3360007.


Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK. Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects. Nucleic Acids Res. 2012 Jul 1;40(12):5560-5568. Epub 2012 Feb 28. PubMed PMID: 22373919; PubMed Central PMCID: PMC3384306.


Redwine WB, Hernández-López R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE. Structural basis for microtubule binding and release by dynein. Science. 2012 Sep 21;337(6101):1532-6. PMID: 22997337 PMCID: PMC3919166 read article


Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D'Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE. An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature. 2012 Nov 15;491(7424):449-53. doi: 10.1038/nature11624. Epub 2012 Oct 31. PMID: 23123854 PMCID: PMC3521494 read article


Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature. 2012 Jan 18;481(7381):295-305. doi: 10.1038/nature10761. Review. PubMed PMID: 22258608 PMCID: PMC3652331 read article


Rosetti F, Tsuboi N, Chen K, Nishi H, Ernandez T, Sethi S, Croce K, Stavrakis G, Alcocer-Varela J, Gómez-Martin D, van Rooijen N, Kyttaris VC, Lichtman AH, Tsokos GC, Mayadas TN. Human lupus serum induces neutrophil-mediated organ damage in mice that is enabled by Mac-1 deficiency J Immunol. 2012 Oct 1;189(7):3714-23. Epub 2012 Aug 29. PMID: 22933624 PMCID: PMC3462585 read article


Crispín JC, Apostolidis SA, Rosetti F, Keszei M, Wang N, Terhorst C, Mayadas TN, Tsokos GC. Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism. J Immunol. 2012 Apr 15;188(8):3567-71. doi: 10.4049/jimmunol.1200143. Epub 2012 Mar 14. PMID: 22422882 PMCID: PMC3324672 read article


Gohda T, Niewczas MA, Ficociello LH, Walker WH, Skupien J, Rosetti F, Cullere X, Johnson AC, Crabtree G, Smiles AM, Mayadas TN, Warram JH, Krolewski AS. Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes. J Am Soc Nephrol. 2012 Mar;23(3):516-24. doi: 10.1681/ASN.2011060628. Epub 2012 Jan 19. PMID: 22266664 PMCID: PMC3294299 read article


Niewczas MA, Gohda T, Skupien J, Smiles AM, Walker WH, Rosetti F, Cullere X, Eckfeldt JH, Doria A, Mayadas TN, Warram JH, Krolewski AS. Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes. J Am Soc Nephrol. 2012 Mar;23(3):507-15. doi: 10.1681/ASN.2011060627. Epub 2012 Jan 19. PMID:22266663 PMCID: PMC3294310 read article


Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nat Immunol. 2012 Dec 23. doi: 10.1038/ni.2509. [Epub ahead of print] PubMed PMID: 23263557.


Sage, P. T., L. M. Varghese, R. Martinelli, T. E. Sciuto, M. Kamei, A. M. Dvorak, T. A. Springer, A. H. Sharpe, and C. V. Carman. 2012. Antigen Recognition Is Facilitated by Invadosome-like Protrusions Formed by Memory/Effector T Cells. J Immunol 188:3686-3699.


Sage, P. T., L. M. Francisco, C. V. Carman, and A. H. Sharpe. 2012. The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood. Nature immunology.


Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME. Bhlhb5 and prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303. PubMed PMID: 22284184; PubMed Central PMCID: PMC3269007.


Neale BM, Kou Y, Liu L, Ma'ayan A, Samocha KE, Sabo A, Lin CF, Stevens C, Wang LS, Makarov V, Polak P, Yoon S, Maguire J, Crawford EL, Campbell NG, Geller ET, Valladares O, Schafer C, Liu H, Zhao T, Cai G, Lihm J, Dannenfelser R, Jabado O, Peralta Z, Nagaswamy U, Muzny D, Reid JG, Newsham I, Wu Y, Lewis L, Han Y, Voight BF, Lim E, Rossin E, Kirby A, Flannick J, Fromer M, Shakir K, Fennell T, Garimella K, Banks E, Poplin R, Gabriel S, DePristo M, Wimbish JR, Boone BE, Levy SE, Betancur C, Sunyaev S, Boerwinkle E, Buxbaum JD, Cook EH Jr, Devlin B, Gibbs RA, Roeder K, Schellenberg GD, Sutcliffe JS, Daly MJ. Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature. 2012 Apr 4;485(7397):242-5. doi: 10.1038/nature11011. PMID: 22495311 PMCID: PMC3613847 read article


Liu T, Kong D, Shah BP, Ye C, Koda S, Saunders A, Ding JB, Yang Z, Sabatini BL, Lowell BB. Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone. Neuron. 2012 Feb 9;73(3):511-22. doi: 10.1016/j.neuron.2011.11.027. PMID: 22325203 PMCID: PMC3278709 read article


Kozorovitskiy Y, Saunders A, Johnson CA, Lowell BB, Sabatini BL. Recurrent network activity drives striatal synaptogenesis. Nature. 2012 May 13;485(7400):646-50. doi: 10.1038/nature11052. PMID: 22660328 PMCID: PMC3367801 read article


Saunders A, Johnson CA, Sabatini BL. Novel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons. Front Neural Circuits. 2012 Jul 27;6:47. doi: 10.3389/fncir.2012.00047. eCollection 2012. PMID: 22866029 PMCID: PMC3406316 read article


Beliveau BJ, Joyce EF, Apostolopoulos N, Yilmaz F, Fonseka CY, McCole RB, Chang Y, Li JB, Senaratne TN, Williams BR, Rouillard JM, Wu CT. Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21301-6. doi: 10.1073/pnas.1213818110. Epub 2012 Dec 11. PMID: 23236188 PMCID: PMC3535588 read article


Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, Choi K, de Waal L, Sharifnia T, Brooks A, Greulich H, Banerji S, Zander T, Seidel D, Leenders F, Ansén S, Ludwig C, Engel-Riedel W, Stoelben E, Wolf J, Goparju C, Thompson K, Winckler W, Kwiatkowski D, Johnson BE, Jänne PA, Miller VA, Pao W, Travis WD, Pass HI, Gabriel SB, Lander ES, Thomas RK, Garraway LA, Getz G, Meyerson M. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 2012 Sep 14;150(6):1107-20. doi: 10.1016/j.cell.2012.08.029. PMID: 22980975 PMCID: PMC3557932 read article


Sikorski TW, Joo YJ, Ficarro SB, Askenazi M, Buratowski S, Marto JA. Proteomic analysis demonstrates activator- and chromatin-specific recruitment to promoters. J Biol Chem. 2012 Oct 12;287(42):35397-408. doi: 10.1074/jbc.M112.391581. Epub 2012 Aug 17. PMID: 22902623 PMCID: PMC3471693 read article


Akopian V, Chan MM, Clement K, Galonska C, Gifford CA, Lehtola E, Liao J, Samavarchi-Tehrani P, Sindhu C, Smith ZD, Tsankov AM, Webster J, Zhang Y, Ziller MJ, Meissner A. Epigenomics and chromatin dynamics. Genome Biol. 2012 Feb 24;13(2):313. doi: 10.1186/gb-2012-13-2-313. PMID: 22364154 PMCID: PMC3334565 read article


Sindhu C, Samavarchi-Tehrani P, Meissner A. Transcription factor-mediated epigenetic reprogramming. J Biol Chem. 2012 Sep 7;287(37):30922-31. doi: 10.1074/jbc.R111.319046. Epub 2012 Sep 5. PMID: 22952239 PMCID: PMC3438925 read article


Soghoian DZ, Jessen H, Flanders M, Sierra-Davidson K, Cutler S, Pertel T, Ranasinghe S, Lindqvist M, Davis I, Lane K, Rychert J, Rosenberg ES, Piechocka-Trocha A, Brass AL, Brenchley JM, Walker BD, Streeck H. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci Transl Med. 2012 Feb 29;4(123):123ra25. doi: 10.1126/scitranslmed.3003165. PMID: 22378925 PMCID: PMC3918726 read article


Lindqvist M, van Lunzen J, Soghoian DZ, Kuhl BD, Ranasinghe S, Kranias G, Flanders MD, Cutler S, Yudanin N, Muller MI, Davis I, Farber D, Hartjen P, Haag F, Alter G, Schulze zur Wiesch J, Streeck H. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest. 2012 Sep 4;122(9):3271-80. doi: 10.1172/JCI64314. Epub 2012 Aug 27. PMID: 22922259 PMCID: PMC3428098 read article


Ranasinghe S, Flanders M, Cutler S, Soghoian DZ, Ghebremichael M, Davis I, Lindqvist M, Pereyra F, Walker BD, Heckerman D, Streeck H. HIV-specific CD4 T cell responses to different viral proteins have discordant associations with viral load and clinical outcome. J Virol. 2012 Jan;86(1):277-83. doi: 10.1128/JVI.05577-11. Epub 2011 Oct 26. PMID: 22031937 PMCID: PMC3255877 read article


Ho HY, Susman MW, Bikoff JB, Ryu YK, Jonas AM, Hu L, Kuruvilla R, Greenberg ME. Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4044-51. doi: 10.1073/pnas.1200421109. Epub 2012 Feb 17. PMID: 22343533 PMCID: PMC3306699 read article


Harper JW, Tan MK. Understanding cullin-RING E3 biology through proteomics-based substrate identification. Mol Cell Proteomics. 2012 Dec;11(12):1541-50. doi: 10.1074/mcp.R112.021154. Epub 2012 Sep 7. PMID: 22962057 PMCID: PMC3518111 read article


White EA, Kramer RE, Tan MJ, Hayes SD, Harper JW, Howley PM. Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity. J Virol. 2012 Dec;86(24):13174-86. doi: 10.1128/JVI.02172-12. Epub 2012 Sep 26. PMID: 23015706 PMCID: PMC3503137 read article


White EA, Sowa ME, Tan MJ, Jeudy S, Hayes SD, Santha S, Münger K, Harper JW, Howley PM. Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):E260-7. doi: 10.1073/pnas.1116776109. Epub 2012 Jan 9. PMID: 22232672 PMCID: PMC3277141 read article


Tan MJ, White EA, Sowa ME, Harper JW, Aster JC, Howley PM. Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):E1473-80. doi: 10.1073/pnas.1205991109. Epub 2012 Apr 30. PMID: 22547818 PMCID: PMC3384212 read article


Taylor AM, Humphries JM, White RM, Murphey RD, Burns CE, Zon LI. Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Exp Hematol. 2012 Mar;40(3):228-237.e5. doi: 10.1016/j.exphem.2011.11.007.. Epub 2011 Nov 25. PMID: 22120640 PMCID: PMC3310385 read article


Tamplin OJ, White RM, Jing L, Kaufman CK, Lacadie SA, Li P, Taylor AM, Zon LI. Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley Interdiscip Rev Dev Biol. 2012 May-Jun;1(3):459-68. doi: 10.1002/wdev.37. Epub 2012 Feb 28. PMID: 23801494


Chu Y, Fioravante D, Thanawala M, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held. J Neurosci. 2012 Oct 3;32(40):13796-804. doi: 10.1523/JNEUROSCI.2158-12.2012. PMID: 23035091 PMCID: PMC3626456 read article


Rajani DK, Walch M, Martinvalet D, Thomas MP, Lieberman J. Alterations in RNA processing during immune-mediated programmed cell death. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8688-93. doi: 10.1073/pnas.1201327109. Epub 2012 May 15. PMID: 22589304 PMCID: PMC3365155 read article


Thompson DB, Cronican JJ, Liu DR. Engineering and identifying supercharged proteins for macromolecule delivery into mammalian cells. Methods Enzymol. 2012;503:293-319. doi: 10.1016/B978-0-12-396962-0.00012-4. PMID: 22230574 PMCID: PMC3505079 read article


Thompson DB, Villaseñor R, Dorr BM, Zerial M, Liu DR. Cellular uptake mechanisms and endosomal trafficking of supercharged proteins. Chem Biol. 2012 Jul 27;19(7):831-43. doi: 10.1016/j.chembiol.2012.06.014. PMID: 22840771 PMCID: PMC3408882 read article


Tsanov KM, Nishi Y, Peterson KA, Liu J, Baetscher M, McMahon AP. An embryonic stem cell-based system for rapid analysis of transcriptional enhancers. Genesis. 2012 May;50(5):443-50. doi: 10.1002/dvg.20820. Epub 2012 Jan 17. PMID: 22083581 PMCID: PMC3334447.  read article


Ching S, Purdon PL, Vijayan S, Kopell NJ, Brown EN. A neurophysiological-metabolic model for burst suppression. Proc Natl Acad Sci U S A. 2012 Feb 7. [Epub ahead of print] PubMed PMID: 22323592. PMCID: PMC Journal in Process


Vo TT, Ryan J, Carrasco R, Neuberg D, Rossi DJ, Stone RM, Deangelo DJ, Frattini MG, Letai A. Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML. Cell. 2012 Oct 12;151(2):344-55. doi: 10.1016/j.cell.2012.08.038. PMID: 23063124 PMCID: PMC3534747 read article


Williams LA, Davis-Dusenbery BN, Eggan KC. SnapShot: directed differentiation of pluripotent stem cells. Cell. 2012 May 25;149(5):1174-1174.e1. doi: 10.1016/j.cell.2012.05.015. PMID: 22632979


Wivagg CN, Hung DT. Resuscitation-promoting factors are required for β-lactam tolerance and the permeability barrier in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2012 Mar;56(3):1591-4. doi: 10.1128/AAC.06027-11. Epub 2011 Dec 12. PMID: 22155826 PMCID: PMC3294900 read article


Stanley SA, Grant SS, Kawate T, Iwase N, Shimizu M, Wivagg C, Silvis M, Kazyanskaya E, Aquadro J, Golas A, Fitzgerald M, Dai H, Zhang L, Hung DT. Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening. ACS Chem Biol. 2012 Aug 17;7(8):1377-84. doi: 10.1021/cb300151m. Epub 2012 May 21. PMID: 22577943 PMCID: PMC3560293 read article


Acton S, Astarita J, Malhotra D, Lukacs-Kornek V, Franz B, Hess P, Jakus Z, Kuligowski M, Fletcher A, Elpek K, Bellemare-Pelletier A, Sceats L, Reynoso E, Gonzalez S, Graham D, Chang J, Peters A, Woodruff M, Kim Y, Swat W, Morita T, Kuchroo V, Carroll M, Kahn M, Wucherpfennig K, Turley S Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2 Immunity. 2012 Aug 24;37(2):276-89. doi: 10.1016/j.immuni.2012.05.022. Epub 2012 Aug 9. PMID: 22884313 PMCID: PMC3556784 read article


Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11920-7. doi: 10.1073/pnas.1201904109. Epub 2012 Jul 13. PMID: 22797899 PMCID: PMC3409785 read article


Kim H, Yang K, Dejsuphong D, D'Andrea AD. Regulation of Rev1 by the Fanconi anemia core complex. Nat Struct Mol Biol. 2012 Jan 22;19(2):164-70. doi: 10.1038/nsmb.2222. PubMed PMID: 22266823; PubMed Central PMCID: PMC3280818.


Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 13. [Epub ahead of print] PubMed PMID: 22797899.


Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res. 2012 Jun 26. [Epub ahead of print] PubMed PMID: 22740649.


Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL, Adelmant G, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J, Marto JA, Hill DE, Cusick ME, Vidal M, Florens L, Washburn MP, Litovchick L, DeCaprio JA. Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog. 2012;8(10):e1002949. doi: 10.1371/journal.ppat.1002949. Epub 2012 Oct 18. PMID: 23093934 PMCID: PMC3475652 read article


Yu Y, Munger K. Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint. Virology. 2012 Oct 10;432(1):120-6. doi: 10.1016/j.virol.2012.06.006. Epub 2012 Jun 28. PMID: 22748180 PMCID: PMC3402702 read article


Zeng X, King RW. An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nat Chem Biol. 2012 Feb 26;8(4):383-92. doi: 10.1038/nchembio.801. PubMed PMID: 22366722; PubMed Central PMCID: PMC3307893.


Christofferson DE, Li Y, Hitomi J, Zhou W, Upperman C, Zhu H, Gerber SA, Gygi S, Yuan J .A novel role for RIP1 kinase in mediating TNFα production. Cell Death Dis. 2012 Jun 14;3:e320. doi: 10.1038/cddis.2012.64. PMID: 22695613 PMCID: PMC3388236 read article


Zhou W, Yuan J. Cell biology: Death by deacetylation. Nature. 2012 Dec 13;492(7428):194-5. doi: 10.1038/nature11761. Epub 2012 Nov 28. PMID:23201692


top

2011


Li L, Rutlin M, Abraira VE, Cassidy C, Kus L, Gong S, Jankowski MP, Luo W,Heintz N, Koerber HR, Woodbury CJ, Ginty DD. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 2011 Dec 23;147(7):1615-27. PubMed PMID: 22196735; PubMed Central PMCID: PMC3262167.


Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Tothova Z, Attar E, Frohling S, DePinho RA, Gilliland DG, Armstrong SA, Scadden DT. AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell. 2011 Sep 2;146(5):697-708. doi: 10.1016/j.cell.2011.07.032. PMID: 21884932 PMCID: PMC3826540 read article


Barstow B, Agapakis CM, Boyle PM, Grandl G, Silver PA, Wintermute EH. A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism. J Biol Eng. 2011 May 26;5:7. doi: 10.1186/1754-1611-5-7. PMID: 21615937 PMCID: PMC3130634 read article


Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, Silver PA. Towards a synthetic chloroplast. PLoS One. 2011 Apr 20;6(4):e18877. doi: 10.1371/journal.pone.0018877. PMID: 21533097 PMCID: PMC3080389 read article


Henrickson SE, Agyemang AF, Garg S, Hafler JP. Integrating clinical perspectives into graduate education. Clin Immunol. 2011 Nov;141(2):228-30PMID: 21944668


Chang YJ, Kim HY, Albacker LA, Baumgarth N, McKenzie ANJ, Smith DE, DeKruyff RH, Umetsu DT (2011) Innate lymphoid cells mediate influenza-induced asthma independent of adaptive immunity. Nat. Immunol. 12(7):631-8. PMID: 21623379 PMCID: PMC3417123


Moldt B, Schultz N, Dunlop DC, Alpert MD, Harvey JD, Evans DT, Poignard P, Hessell AJ, Burton DR. A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV. J Virol. 2011 Oct;85(20):10572-81. Epub 2011 Aug 17. PMID: 21849450 PMCID: PMC3187489 read article


Aoki ST, Trask SD, Coulson BS, Greenberg HB, Dormitzer PR, Harrison SC. Cross-linking of rotavirus outer capsid protein VP7 by antibodies or disulfides inhibits viral entry. J Virol. 2011 Oct;85(20):10509-17. Epub 2011 Aug 17. PMID: 21849465 PMCID: PMC3187514 read article


Appler JM, Goodrich LV. Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly. Prog Neurobiol. 2011 Apr;93(4):488-508. Epub 2011 Jan 11. Review. PubMed PMID: 21232575; PubMed Central PMCID: PMC3078955.


Lu CC, Appler JM, Houseman EA, Goodrich LV. Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly. J Neurosci. 2011 Jul 27;31(30):10903-18. PubMed PMID: 21795542; PubMed Central PMCID: PMC3167573.


Pathak N, Austin CA, Drummond IA. Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility. J Biol Chem. 2011 Apr 1;286(13):11685-95. doi: 10.1074/jbc.M110.209817. Epub 2011 Jan 24. PMID: 21262966 PMCID: PMC3064220 read article


Beier KT, Saunders A, Oldenburg IA, Miyamichi K, Akhtar N, Luo L, Whelan SP, Sabatini B, Cepko CL. Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15414-9. Epub 2011 Aug 8. PubMed PMID: 21825165; PubMed Central PMCID: PMC3174680.


Cronican JJ, Beier KT, Davis TN, Tseng JC, Li W, Thompson DB, Shih AF, May EM, Cepko CL, Kung AL, Zhou Q, Liu DR. A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo. Chem Biol. 2011 Jul 29;18(7):833-8. PubMed PMID: 21802004; PubMed Central PMCID: PMC3154086.


Beier KT, Samson ME, Matsuda T, Cepko CL. Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Dev Biol. 2011 May 15;353(2):309-20. Epub 2011 Mar 21. PubMed PMID: 21397594; PubMed Central PMCID: PMC3100772.


Lucas CL, Workman CJ, Beyaz S, LoCascio S, Zhao G, Vignali DA, Sykes M. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood. 2011 May 19;117(20):5532-40. Epub 2011 Mar 21. PubMed PMID: 21422469; PubMed Central PMCID: PMC3109721. read article


Bilimoria PM, Bonni A. Molecular Regulation of Axon Branching. Neuroscientist. 2011 Dec 15. [Epub ahead of print] PubMed PMID: 22179123. PMCID: PMC Journal in Process


Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature. 2011 Jan 13;469(7329):250-4. Epub 2010 Dec 15. PubMed PMID: 21160472; PubMed Central PMCID: PMC3058373.


Wesemann DR, Magee JM, Boboila C, Calado DP, Gallagher MP, Portuguese AJ, Manis JP, Zhou X, Recher M, Rajewsky K, Notarangelo LD, Alt FW. Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination. J Exp Med. 2011 Dec 19;208(13):2733-46. doi: 10.1084/jem.20111155. Epub 2011 Dec 5. PMID: 22143888 PMCID: PMC3244039 read article


Akselrod-Ballin A, Bock D, Reid RC, Warfield SK. Accelerating image registration with the Johnson-Lindenstrauss lemma: application to imaging 3-D neural ultrastructure with electron microscopy. IEEE Trans Med Imaging. 2011 Jul;30(7):1427-38. Epub 2011 Mar 10. PubMed PMID: 21402511; PubMed Central PMCID: PMC3183508.


Bock DD, Lee WC, Kerlin AM, Andermann ML, Hood G, Wetzel AW, Yurgenson S, Soucy ER, Kim HS, Reid RC. Network anatomy and in vivo physiology of visual cortical neurons. Nature. 2011 Mar 10;471(7337):177-82. PubMed PMID: 21390124; PubMed Central PMCID: PMC3095821.


Behar SM, Martin CJ, Booty MG, Nishimura T, Zhao X, Gan HX, Divangahi M, Remold HG. Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol. 2011 May;4(3):279-87. doi: 10.1038/mi.2011.3. Epub 2011 Feb 9. PMID: 21307848; PubMed Central PMCID: PMC3155700.  read article


Bowen ME, Boyden ED, Holm IA, Campos-Xavier B, Bonafé L, et al. (2011) Loss-of-function mutations in PTPN11 cause Metachondromatosis, but not Ollier disease or Maffucci syndrome. PLoS Genetics 7(4):e1002050. PMCID:PMC3077396.


Burrill DR, Boyle PM, Silver PA. A new approach to an old problem: synthetic biology tools for human disease and metabolism. Cold Spring Harb Symp Quant Biol. 2011;76:145-54. doi: 10.1101/sqb.2011.76.010686. Epub 2011 Dec 14. PMID: 22169233


Senapedis WT, Kennedy CJ, Boyle PM, Silver PA. Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. Mol Biol Cell. 2011 May 15;22(10):1791-805. doi: 10.1091/mbc.E10-10-0854. Epub 2011 Apr 1. PMID: 21460183 PMCID: PMC3093329 read article


Barstow B, Agapakis CM, Boyle PM, Grandl G, Silver PA, Wintermute EH. A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism. J Biol Eng. 2011 May 26;5:7. doi: 10.1186/1754-1611-5-7. PMID: 21615937 PMCID: PMC3130634 read article


Paterson AM, Brown KE, Keir ME, Vanguri VK, Riella LV, Chandraker A, Sayegh MH, Blazar BR, Freeman GJ, Sharpe AH. The programmed death-1 ligand 1:b7-1 pathway restrains diabetogenic effector T cells in vivo. J Immunol. 2011 Aug 1;187(3):1097-105. Epub 2011 Jun 22. PubMed PMID: 21697456; PubMed Central PMCID: PMC3148082.


Ray, R.S.*, Corcoran, A.E.*, Brust, R.D.*, Kim, J.C., Richerson, G.B., Nattie, E., Dymecki, S.M. Impaired Respiratory and Body Temperature Control Upon Acute Serotonergic Neuron Inhibition. Science. 2011 Jul 29;333(6042):637-42. doi: 10.1126/science.1205295. PMID: 21798952 PMCID: PMC3729433 *- These authors contributed equally to this work. read article


Buchman JJ, Durak O, Tsai LH. ASPM regulates Wnt signaling pathway activity in the developing brain. Genes Dev. 2011 Sep 15;25(18):1909-14. doi:10.1101/gad.16830211. PubMed PMID: 21937711; PubMed Central PMCID: PMC3185963.


Burrill DR, Silver PA. Synthetic circuit identifies subpopulations with sustained memory of DNA damage. Genes Dev. 2011 Mar 1;25(5):434-9. doi: 10.1101/gad.1994911. PMID: 21363961 PMCID: PMC3049284 read article


Burrill DR, Silver PA. Recording cellular experiences of DNA damage. Cell Cycle. 2011 Aug 1;10(15):2410-1. Epub 2011 Aug 1. PMID: 21670599


Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9. PMID: 21307310 PMCID: PMC3048138 read article


Alkuraya FS, Cai X, Emery C, Mochida GH, Al-Dosari MS, Felie JM, Hill RS, Barry BJ, Partlow JN, Gascon GG, Kentab A, Jan M, Shaheen R, Feng Y, Walsh CA. Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]. Am J Hum Genet. 2011 May 13;88(5):536-47. doi: 10.1016/j.ajhg.2011.04.003. Epub 2011 Apr 28. PMID: 21529751 PMCID: PMC3146728 read article


Cale EM, Hraber P, Giorgi EE, Fischer W, Bhattacharya T, Leitner T, Yeh WW, Gleasner C, Green LD, Han CS, Korber B, Letvin NL. Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection. J Virol. 2011 Apr;85(8):3746-57. Epub 2011 Feb 9. PMID: 21307185 PMCID: PMC3126128


Hulot SL, Cale EM, Korber BT, Letvin NL. Vaccine-induced CD8+ T lymphocytes of rhesus monkeys recognize variant forms of an HIV epitope but do not mediate optimal functional activity. J Immunol. 2011 May 15;186(10):5663-74. Epub 2011 Apr 13. PubMed PMID: 21490161


Cale EM, Bazick HS, Rianprakaisang TA, Alam SM, Letvin NL. Mutations in a Dominant Nef Epitope of SIVmac Diminish TCR:Epitope Peptide Affinity but not Epitope Peptide:MHC Class I Binding. J Immunol. 2011 Sep 15;187(6):3300-13. doi: 10.4049/jimmunol.1101080. Epub 2011 Aug 12. PMID: 21841125 PMCID: PMC3175636


Carter BC, Bean BP. Incomplete inactivation and rapid recovery ofvoltage-dependent sodium channels during high-frequency firing in cerebellar Purkinje neurons. J Neurophysiol. 2011 Feb;105(2):860-71. Epub 2010 Dec 15. PubMed PMID: 21160003; PubMed Central PMCID: PMC3059179.


Barthel SR, Antonopoulos A, Cedeno-Laurent F, Schaffer L, Hernandez G, Patil SA, North SJ, Dell A, Matta KL, Neelamegham S, Haslam SM, Dimitroff CJ. Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation. J Biol Chem. 2011 Jun 17;286(24):21717-31. Epub 2011 Apr 14. PubMed PMID: 21493714; PubMed Central PMCID: PMC3122228.


Cedeno-Laurent F, Penalva de Oliveira AC, Vidal JE, Trujillo JR. Human Polyomavirus-Associated Cerebral Disorders in the Post-HAART Era. Patholog Res Int. 2011 Feb 22;2011:562427. PubMed PMID: 21437187; PubMed Central PMCID: PMC3062102.


Cedeno-Laurent F, Gómez-Flores M, Mendez N, Ancer-Rodríguez J, Bryant JL,Gaspari AA, Trujillo JR. New insights into HIV-1-primary skin disorders. J Int AIDS Soc. 2011 Jan 24;14:5. Review. PubMed PMID: 21261982; PubMed Central PMCID: PMC3037296.


Chan Y, Holmen OL, Dauber A, Vatten L, Havulinna AS, Skorpen F, Kvaløy K, Silander K, Nguyen TT, Willer C, Boehnke M, Perola M, Palotie A, Salomaa V, Hveem K, Frayling TM, Hirschhorn JN, Weedon MN. Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals. PLoS Genet. 2011 Dec;7(12):e1002439. doi: 10.1371/journal.pgen.1002439. Epub 2011 Dec 29. PMID: 22242009 PMCID: PMC3248463 read article


Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, Degrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U, Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N. Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits. Cell. 2011 Nov 11;147(4):853-67. PubMed PMID: 22078882


Dauber A, Yu Y, Turchin MC, Chiang CW, Meng YA, Demerath EW, Patel SR, Rich SS, Rotter JI, Schreiner PJ, Wilson JG, Shen Y, Wu BL, Hirschhorn JN. Genome-wide association of copy-number variation reveals an association between short stature and the presence of low-frequency genomic deletions. Am J Hum Genet. 2011 Dec 9;89(6):751-9. Epub 2011 Nov 23. PubMed PMID: 22118881; PubMed Central PMCID: PMC3234379.


Chiang CW, Gajdos ZK, Korn JM, Butler JL, Hackett R, Guiducci C, Nguyen TT, Wilks R, Forrester T, Henderson KD, Le Marchand L, Henderson BE, Haiman CA, Cooper RS, Lyon HN, Zhu X, McKenzie CA, Palmert MR, Hirschhorn JN. The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA. Hum Genet. 2011 Nov;130(5):607-21. Epub 2011 Mar 22. PubMed PMID: 21424828.


Zhu X, Young JH, Fox E, Keating BJ, Franceschini N, Kang S, Tayo B, Adeyemo A, Sun YV, Li Y, Morrison A, Newton-Cheh C, Liu K, Ganesh SK, Kutlar A, Vasan RS, Dreisbach A, Wyatt S, Polak J, Palmas W, Musani S, Taylor H, Fabsitz R, Townsend RR, Dries D, Glessner J, Chiang CW, Mosley T, Kardia S, Curb D, Hirschhorn JN, Rotimi C, Reiner A, Eaton C, Rotter JI, Cooper RS, Redline S, Chakravarti A, Levy D. Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: contributions from the CARe consortium. Hum Mol Genet. 2011 Jun 1;20(11):2285-95. Epub 2011 Mar 21. PubMed PMID: 21422096; PubMed Central PMCID: PMC3090198.


Christodoulou DC, Gorham JM, Herman DS, Seidman JG. Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease. Curr Protoc Mol Biol. 2011 Apr;Chapter 4:Unit4.12. PubMed PMID: 21472699; PubMed Central PMCID: PMC3152986.


Alon S, Vigneault F, Eminaga S, Christodoulou DC, Seidman JG, Church GM, Eisenberg E. Barcoding bias in high-throughput multiplex sequencing of miRNA. Genome Res. 2011 Sep;21(9):1506-11. Epub 2011 Jul 12. PubMed PMID: 21750102; PubMed Central PMCID: PMC3166835.


Fioravante D, Chu Y, Myoga MH, Leitges M, Regehr WG. Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held. Neuron. 2011 Jun 9;70(5):1005-19. doi: 10.1016/j.neuron.2011.04.019. PMID: 21658591 PMCID: PMC3113702 read article


Brigl M, Tatituri RV, Watts GF, Bhowruth V, Leadbetter EA, Barton N, Cohen NR, Hsu FF, Besra GS, Brenner MB. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. J Exp Med. 2011 Jun 6;208(6):1163-77. Epub 2011 May 9. PMID: 21555485 PMCID:PMC3173255


Cohen NR, Tatituri RV, Rivera A, Watts GF, Kim EY, Chiba A, Fuchs BB, Mylonakis E, Besra GS, Levitz SM, Brigl M, Brenner MB. Innate recognition of cell wall β-glucans drives invariant natural killer T cell responses against fungi. Cell Host Microbe. 2011 Nov 17;10(5):437-50. doi: 10.1016/j.chom.2011.09.011. PMID: 22100160


Wang L, Colodner KJ, Feany MB. Protein misfolding and oxidative stress promote glial-mediated neurodegeneration in an Alexander disease model. J Neurosci. 2011 Feb 23;31(8):2868-77. PubMed PMID: 21414908; PubMed Central PMCID: PMC3082397.


Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol. 2011 Feb;29(2):149-53. Epub 2011 Jan 19. PubMed PMID: 21248753; PubMed Central PMCID: PMC3084533.  read article


Cornejo MG, Mabialah V, Sykes SM, Khandan T, Lo Celso C, Lopez C, Rivera-Muñoz P, Rameau P, Tothova Z, Aster JC, Depinho RA, Scadden DT, Gilliland DG, Mercher T. Crosstalk between Notch and AKT signaling during murine megakaryocyte lineage specification. Blood. 2011 Jun 7. [Epub ahead of print] PMID: 21653327 PMCID: PMC3152494


Baecher-Allan CM, Costantino CM, Cvetanovich GL, Ashley CW, Beriou G, Dominguez-Villar M, Hafler DA. CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis. J Immunol. 2011 Mar 15;186(6):3317-26. Epub 2011 Feb 7. PubMed PMID: 21300823.


Courchesne SL, Karch C, Pazyra-Murphy MF, Segal RA. Sensory neuropathy attributable to loss of Bcl-w. J Neurosci. 2011 Feb 2;31(5):1624-34. PubMed PMID: 21289171; PubMed Central PMCID: PMC3074348.


Courchesne SL, Pazyra-Murphy MF, Lee DJ, Segal RA. Neuromuscular junction defects in mice with mutation of dynein heavy chain 1. PLoS One. 2011 Feb 4;6(2):e16753. PubMed PMID: 21346813; PubMed Central PMCID: PMC3035627.


Park KS, Liang MC, Raiser DM, Zamponi R, Roach RR, Curtis SJ, Walton Z, Schaffer BE, Roake CM, Zmoos AF, Kriegel C, Wong KK, Sage J, Kim CF. Characterization of the cell of origin for small cell lung cancer. Cell Cycle. 2011 Aug 15;10(16):2806-15. Epub 2011 Aug 15. PubMed PMID: 21822053; PubMed Central PMCID: PMC3219544.


Kasprowicz VO, Mitchell JE, Chetty S, Govender P, Huang KH, Fletcher HA, Webster DP, Brown S, Kasmar A, Millington K, Day CL, Mkhwanazi N, McClurg C, Chonco F, Lalvani A, Walker BD, Ndung'u T, Klenerman P. A molecular assay for sensitive detection of pathogen-specific T-cells. PLoS One. 2011;6(8):e20606. doi: 10.1371/journal.pone.0020606. Epub 2011 Aug 11. PMID: 21853018 PMCID: PMC3154901 read article


Kay JN, De la Huerta I, Kim IJ, Zhang Y, Yamagata M, Chu MW, Meister M, Sanes JR. Retinal ganglion cells with distinct directional preferences differ in molecular identity, structure, and central projections. J Neurosci. 2011 May 25;31(21):7753-62. PubMed PMID: 21613488; PubMed Central PMCID: PMC3108146.


Christensen R, de la Torre-Ubieta L, Bonni A, Colón-Ramos DA. A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development. Development. 2011 Dec;138(23):5257-67. PubMed PMID: 22069193; PubMed Central PMCID: PMC3210501.


Huynh MA, Ikeuchi Y, Netherton S, de la Torre-Ubieta L, Kanadia R, Stegmüller J, Cepko C, Bonni S, Bonni A. An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron. 2011 Mar 10;69(5):930-44. PubMed PMID: 21382553; PubMed Central PMCID: PMC3073069.


de Vries SE, Baccus SA, Meister M. The projective field of a retinal amacrine cell. J Neurosci. 2011 Jun 8;31(23):8595-604. PubMed PMID: 21653863; PubMed Central PMCID: PMC3130123.


Deans MR, Krol A, Abraira VE, Copley CO, Tucker AF, Goodrich LV. Control of
neuronal morphology by the atypical cadherin Fat3. Neuron. 2011 Sep
8;71(5):820-32. PubMed PMID: 21903076.


Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF,Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U, Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell. 2011 Nov 11;147(4):853-67. PubMed PMID: 22078882.


Yang HT, Wang Y, Zhao X, Demissie E, Papoutsopoulou S, Mambole A, O'Garra A, Tomczak MF, Erdman SE, Fox JG, Ley SC, Horwitz BH. NF-κB1 inhibits TLR-induced IFN-β production in macrophages through TPL-2-dependent ERK activation. J Immunol. 2011 Feb 15;186(4):1989-96. Epub 2011 Jan 7. PubMed PMID: 21217011; PubMed Central PMCID: PMC3070925.  read article


Dietz SB, Markopoulos F, Murthy VN. Postnatal development of dendrodendritic inhibition in the Mammalian olfactory bulb. Front Cell Neurosci. 2011;5:10. Epub 2011 Jun 27. PubMed PMID: 21738497; PubMed Central PMCID: PMC3125518.


Dougan M, Li D, Neuberg D, Mihm M, Googe P, Wong KK, Dranoff G. A dual rolefor the immune response in a mouse model of inflammation-associated lung cancer. J Clin Invest. 2011 May 2. pii: 44796. doi: 10.1172/JCI44796. [Epub ahead of print] PMID: 21537082


Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, Donahue RE, North TE. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 2011 Apr 8;8(4):445-58. doi: 10.1016/j.stem.2011.02.003. PMID: 21474107 PMCID: PMC3148081 read article


Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, Paulson RF, Young RA, Zon LI. Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell. 2011 Oct 28;147(3):577-89. PubMed PMID: 22036566; PubMed Central PMCID: PMC3219441.


Anderl S, Freeland M, Kwiatkowski DJ, Goto J. (2011)Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex. Hum Mol Genet. 2011 Dec 1;20(23):4597-604. doi: 10.1093/hmg/ddr393. Epub 2011 Sep 1. PMID: 21890496 PMCID: PMC3209830 read article


Kim T, Escudero S, and Shivdasani RA. Intact function of Lgr5-expressing intestinal stem cells in the absence of paneth cells. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3932-7. doi: 10.1073/pnas.1113890109. Epub 2012 Feb 21. PMID: 22355124 PMCID: PMC3309789 read article


Sukumaran B, Mastronunzio JE, Narasimhan S, Fankhauser S, Uchil PD, Levy R, Graham M, Colpitts TM, Lesser CF, Fikrig E. Anaplasma phagocytophilum AptA modulates Erk1/2 signalling. Cell Microbiol. 2011 Jan;13(1):47-61. doi: 10.1111/j.1462-5822.2010.01516.x. Epub 2010 Aug 27. PMID: 20716207 PMCID: PMC3005019 read article


Ferrero DM, Lemon JK, Fluegge D, Pashkovski SL, Korzan WJ, Datta SR, Spehr M, Fendt M, Liberles SD. Detection and avoidance of a carnivore odor by prey. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11235-40. Epub 2011 Jun 20. PubMed PMID: 21690383; PubMed Central PMCID: PMC3131382.


Li X, Yeung DF, Fiegen AM, Sodroski J. Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins. J Biol Chem. 2011 Aug 12;286(32):27959-70. Epub 2011 Jun 16. PMID: 21680743 PMCID: PMC3151041 read article


Finley LW, Haas W, Desquiret-Dumas V, Wallace DC, Procaccio V, Gygi SP, Haigis MC. Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. PLoS One 2011;6(8):e23295. Epub 2011 Aug 17. PMID: 21858060. PMCID: PMC3157345.


Fitzgerald JK, Freedman DJ, Assad JA. Generalized associative representations in parietal cortex. Nat Neurosci. 2011 Jul 17;14(8):1075-9. doi: 10.1038/nn.2878. PubMed PMID: 21765425; PubMed Central PMCID: PMC3145031.


Ford KM, Saint-Geniez M, Walshe T, Zahr A, D'Amore PA. Expression and role of VEGF in the adult retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2011 Dec 9;52(13):9478-87. doi: 10.1167/iovs.11-8353. PMID: 22058334 PMCID: PMC3250352 read article


Garg S, Sharma M, Ung C, Tuli A, Barral DC, Hava DL, Veerapen N, Besra GS, Hacohen N, Brenner MB. Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b. Immunity. 2011 Aug 26;35(2):182-93. Epub 2011 Jul 28. PMID: 21802320. PMCID: PMC3584282


Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB; CKDGen Consortium, Rotimi CN, Liu Y, Kardia SL, Evans MK, Shlipak MG, Kramer H, Flessner MF, Dreisbach AW, Goessling W, Cupples LA, Kao WL, Fox CS. Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet. 2011 Sep;7(9):e1002264. Epub 2011 Sep 8. PubMed PMID: 21931561; PubMed Central PMCID: PMC3169523. read article


Giessel AJ, Sabatini BL. Boosting of synaptic potentials and spine Ca transients by the peptide toxin SNX-482 requires alpha-1E-encoded voltage-gated Ca channels. PLoS One. 2011;6(6):e20939. Epub 2011 Jun 9. PubMed PMID: 21695265; PubMed Central PMCID: PMC3111456.


Gomila RC, Martin GW, Gehrke L. NF90 binds the dengue virus RNA 3' terminus and is a positive regulator of dengue virus replication. PLoS One. 2011 Feb 28;6(2):e16687. doi: 10.1371/journal.pone.0016687. PMID: 21386893 PMCID: PMC3046124 read article


Puram SV, Kim AH, Ikeuchi Y, Wilson-Grady JT, Merdes A, Gygi SP, Bonni A. A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat Neurosci. 2011 Jul 3;14(8):973-83. doi: 10.1038/nn.2857. PMID: 21725312 PMCID: PMC3391735 read article


Grassian AR, Coloff JL, Brugge JS. Extracellular matrix regulation of metabolism and implications for tumorigenesis. Cold Spring Harb Symp Quant Biol. 2011;76:313-24. Epub 2011 Nov 21. PubMed PMID: 22105806.


Grassian AR, Metallo CM, Coloff JL, Stephanopoulos G, Brugge JS. Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes Dev. 2011 Aug 15;25(16):1716-33. PubMed PMID: 21852536; PubMed Central PMCID: PMC3165936.


Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. PubMed PMID: 21804546.


Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of recombinant BMP2/7 in utero partially reverses Rubinstein Taybi Syndrome-like skeletal defects induced by Pdk1 or Cbp mutations. J Clin Invest. 2012 Jan 3;122(1):91-106. doi: 10.1172/JCI59466. Epub 2011 Dec 1. PMID: 22133875 PMCID: PMC3248303 read article


Dougan SK, Hu CC, Paquet ME, Greenblatt MB, Kim J, Lilley BN, Watson N, Ploegh HL. Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes. Mol Cell Biol. 2011 Mar;31(6):1145-59. Epub 2011 Jan 10. PMID: 21220515. PMCID: PMC3067910


Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH. MLK3 regulates bone development downstream of the Faciogenital Dysplasia protein FGD1 in mice. J Clin Invest. 2011 Nov;121(11):4383-92. doi: 10.1172/JCI59041. Epub 2011 Oct 3. PMID: 21965325 PMCID: PMC3204846 read article


Castillo M, Hall JA, Correa-Medina M, Ueta C, Kang HW, Cohen DE, Bianco AC. Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality. Diabetes. 2011 Apr;60(4):1082-9. doi: 10.2337/db10-0758. Epub 2011 Feb 18. PMID: 21335378 PMCID: PMC3064082 read article


Han JM, Sahin M. TSC1/TSC2 signaling in the CNS. FEBS Lett. 2011 Apr 6;585(7):973-80. Epub 2011 Feb 15. Review. PubMed PMID: 21329690; PubMed Central PMCID: PMC3070766.


Hayes GD, Riedel CG, Ruvkun G. The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA. Genes Dev. 2011 Oct 1;25(19):2079-92. doi: 10.1101/gad.17153811. PMID: 21979920 PMCID: PMC3197206 read article


Henrickson SE, Agyemang AF, Garg S, Hafler JP. Integrating clinical perspectives into graduate education.Clin Immunol. 2011 Nov;141(2):228-30. Epub 2011 Sep 5. No abstract available. PMID:21944668


Pathania S, Nguyen J, Hill SJ, Scully R, Adelmant GO, Marto JA, Feunteun J, Livingston DM. BRCA1 is required for postreplication repair after UV-induced DNA damage. Mol Cell. 2011 Oct 21;44(2):235-51. Epub 2011 Sep 29. PMID: 21963239. PMCID: PMC3200447. NIHMSID: NIHMS326474


Zheng J, Ho B, Mekalanos JJ. Genetic analysis of anti-amoebae and anti-bacterial activities of the type VI secretion system in Vibrio cholerae. PLoS One. 2011;6(8):e23876. doi: 10.1371/journal.pone.0023876. Epub 2011 Aug 31. PMID: 21909372 PMCID: PMC3166118 read article


Hong S, Quintero-Monzon O, Ostaszewski BL, Podlisny DR, Cavanaugh WT, Yang T, Holtzman DM, Cirrito JR, Selkoe DJ. Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation. J Neurosci. 2011 Nov 2;31(44):15861-9. PubMed PMID: 22049429; PubMed Central PMCID: PMC3227224.


Hong YK, Kim IJ, Sanes JR. Stereotyped axonal arbors of retinal ganglion cell subsets in the mouse superior colliculus. J Comp Neurol. 2011 Jun15;519(9):1691-711. doi: 10.1002/cne.22595. PubMed PMID: 21452242. PMCID - PMC Journal in Process


Houser BL, Tilburgs T, Hill J, Nicotra ML, Strominger JL. (2011). Two unique human decidual macrophage populations. J Immunol. 2011 Feb 15;186(4):2633-42. doi: 10.4049/jimmunol.1003153. Epub 2011 Jan 21. PMID: 21257965 PMCID: PMC3712354 read article


Ponce CR, Hunter JN, Pack CC, Lomber SG, Born RT. Contributions of indirect pathways to visual response properties in macaque middle temporal area MT. J Neurosci. 2011 Mar 9;31(10):3894-903. PubMed PMID: 21389244; PubMed Central PMCID: PMC3117290.


Hunter JN, Born RT. Stimulus-dependent modulation of suppressive influences in MT. J Neurosci. 2011 Jan 12;31(2):678-86. PubMed PMID: 21228177. NIHMSID: 356969.


Huynh MA, Ikeuchi Y, Netherton S, de la Torre-Ubieta L, Kanadia R, Stegmüller J, Cepko C, Bonni S, Bonni A. An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron. 2011 Mar 10;69(5):930-44. doi: 10.1016/j.neuron.2011.02.008. PMID: 21382553 PMCID: PMC3073069 read article


Hyde R, Corkins ME, Somers GA, Hart AC. PKC-1 acts with the ERK MAPK signaling pathway to regulate Caenorhabditis elegans mechanosensory response. Genes Brain Behav. 2011 Apr;10(3):286-98. doi: 10.1111/j.1601-183X.2010.00667.x. Epub 2011 Jan 10. PubMed PMID: 21143768. PMCID: PMC Journal in Process


Lal A, Thomas MP, Altschuler G, Navarro F, O'Day E, Li XL, Concepcion C, Han YC, Thiery J, Rajani DK, Deutsch A, Hofmann O, Ventura A, Hide W, Lieberman J. Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling. PLoS Genet. 2011 Nov;7(11):e1002363. doi: 10.1371/journal.pgen.1002363. Epub 2011 Nov 10. PMID: 22102825 PMCID: PMC3213160 read article


Zimmermann K, Lennerz JK, Hein A, Link AS, Kaczmarek JS, Delling M, Uysal S, Pfeifer JD, Riccio A, Clapham DE. Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18114-9. Epub 2011 Oct 24. PubMed PMID: 22025699; PubMed Central PMCID: PMC3207667.


Lahiri S, Shen K, Klein M, Tang A, Kane E, Gershow M, Garrity P, Samuel AD. Two alternating motor programs drive navigation in Drosophila larva. PLoS One. 2011;6(8):e23180. doi: 10.1371/journal.pone.0023180. Epub 2011 Aug 15. PMID: 21858019 PMCID: PMC3156121 read article


Bock DD, Lee WC, Kerlin AM, Andermann ML, Hood G, Wetzel AW, Yurgenson S, Soucy ER, Kim HS, Reid RC. Network anatomy and in vivo physiology of visual cortical neurons. Nature. 2011 Mar 10;471(7337):177-82. PubMed PMID: 21390124; PubMed Central PMCID: PMC3095821.


Kiely CM, Marguerat S, Garcia JF, Madhani HD, Bähler J, Winston F. Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol. 2011 Oct;31(20):4193-204. doi: 10.1128/MCB.05568-11. Epub 2011 Aug 15. PMID: 21844224 PMCID: PMC3187285 read article


Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker SR, Bloushtain-Qimron N, Kim JJ, Choudhury SA, Maruyama R, Wu Z, Gönen M, Mulvey LA, Bessarabova MO, Huh SJ, Silver SJ, Kim SY, Park SY, Lee HE, Anderson KS, Richardson AL, Nikolskaya T, Nikolsky Y, Liu XS, Root DE, Hahn WC, Frank DA, Polyak K. The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. J Clin Invest. 2011 Jul;121(7):2723-35. doi: 10.1172/JCI44745. PMID: 21633165 PMCID: PMC3223826 read article


Kingston D, Chang H, Ensser A, Lee HR, Lee J, Lee SH, Jung JU, Cho NH. Inhibition of retromer activity by herpesvirus saimiri tip leads to CD4 downregulation and efficient T cell transformation. J Virol. 2011 Oct;85(20):10627-38. Epub 2011 Aug 17. PMID: 21849449 PMCID: PMC3187508 read article


Knoll AT, Muschamp JW, Sillivan SE, Ferguson D, Dietz DM, Meloni EG, Carroll FI, Nestler EJ, Konradi C, Carlezon WA Jr. Kappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats. Biol Psychiatry. 2011 Sep 1;70(5):425-33. Epub 2011 Apr 30. PubMed PMID: 21531393; PubMed Central PMCID: PMC3150294.


Cipolletta D, Kolodin D, Benoist C, and Mathis D. Tissular Tregs: A unique population of adipose-tissue-resident Foxp3+CD4+ T cells that impacts organismal metabolism. Semin Immunol. 2011 Dec;23(6):431-7. doi: 10.1016/j.smim.2011.06.002. Epub 2011 Jul 2. PMID: 21724410


Kim EJ, Hori K, Wyckoff A, Dickel LK, Koundakjian EJ, Goodrich LV, Johnson JE. Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system. J Comp Neurol. 2011 May 1;519(7):1355-70. doi: 10.1002/cne.22574. PubMed PMID: 21452201. PMCID: PMC Journal in Process


Kranzusch PJ, Whelan SP. Arenavirus Z protein controls viral RNA synthesis by locking a polymerase-promoter complex. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19743-8. Epub 2011 Nov 21. PMID: 22106304 PMCID: PMC3241799 read article


Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature. 2011 Aug 24;477(7364):340-3. doi: 10.1038/nature10348. PMID: 21866103 PMCID: PMC3175325 read article


Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH. Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. J Virol. 2011 Sep;85(17):8502-13. Epub 2011 Jun 22. PMID: 21697477 PMCID: PMC3165852 read article


Deans MR, Krol A, Abraira VE, Copley CO, Tucker AF, Goodrich LV. Control ofneuronal morphology by the atypical cadherin Fat3. Neuron. 2011 Sep 8;71(5):820-32. doi: 10.1016/j.neuron.2011.06.026. PMID: 21903076 PMCID: PMC3521586 read article


Sansregret L, Vadnais C, Livingstone J, Kwiatkowski N, Awan A, Cadieux C, Leduy L, Hallett MT, Nepveu A. Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1949-54. doi: 10.1073/pnas.1008403108. Epub 2011 Jan 18. PMID: 21245318 PMCID: PMC3033318 read article


Deng X, Yang Q, Kwiatkowski N, Sim T, McDermott U, Settleman JE, Lee JD, Gray NS. ACS Med Chem Lett. 2011 Mar 10;2(3):195-200. Epub 2011 Jan 12. PMID: 21412406 PMCID: PMC3055678 read article


Miduturu CV, Deng X, Kwiatkowski N, Yang W, Brault L, Filippakopoulos P, Chung E, Yang Q, Schwaller J, Knapp S, King RW, Lee JD, Herrgard S, Zarrinkar P, Gray NS. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors. Chem Biol. 2011 Jul 29;18(7):868-79. doi: 10.1016/j.chembiol.2011.05.010. PMID: 21802008 PMCID: PMC3171802 read article


Zacharek SJ, Fillmore CM, Lau AN, Gludish DW, Chou A, Ho JW, Zamponi R, Gazit R, Bock C, Jäger N, Smith ZD, Kim TM, Saunders AH, Wong J, Lee JH, Roach RR, Rossi DJ, Meissner A, Gimelbrant AA, Park PJ, Kim CF. Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci. Cell Stem Cell. 2011 Sep 2;9(3):272-81. doi: 10.1016/j.stem.2011.07.007. PMID: 21885022 PMCID: PMC3167236 read article


LeBlanc JJ, Fagiolini M. Autism: a "critical period" disorder? Neural Plast. 2011;2011:921680. Epub 2011 Aug 3. Review. PubMed PMID: 21826280; PubMed Central PMCID: PMC3150222.


O'Connell JT, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, LeBleu VS, Dewar R, Rocha RM, Brentani RR, Resnick MB, Neilson EG, Zeisberg M, Kalluri R. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16002-7. Epub 2011 Sep 12. PubMed PMID: 21911392; PubMed Central PMCID: PMC3179047.


Lin Y, Zhang L, Cai AX, Lee M, Zhang W, Neuberg D, Canning CM, Soiffer RJ, Alyea EP, Ritz J, Hacohen N, Means TK, Wu CJ. Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans. J Clin Invest. 2011. 121(4):1574-84. PMCID: PMC3069775.


Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB. Cadherin-11 regulates fibroblast inflammation. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8402-7. doi: 10.1073/pnas.1019437108. Epub 2011 May 2. PMID: 21536877 PMCID: PMC3100978 read article


Peters A, Lee Y, Kuchroo VK. The many faces of Th17 cells. Curr Opin Immunol. 2011 Dec;23(6):702-6. doi: 10.1016/j.coi.2011.08.007. Epub 2011 Sep 6. PMID: 21899997; PMCID: PMC3232281 read article


Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM,Brenner MB. Cadherin-11 regulates fibroblast inflammation. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8402-7. Epub 2011 May 2. PubMed PMID: 21536877; PubMed Central PMCID: PMC3100978.


Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 Aug 29;208(9):1741-7. doi: 10.1084/jem.20110665. Epub 2011 Aug 1. PMID: 21807869 PMCID: PMC3171094 read article


Libedinsky C, Livingstone M. Role of prefrontal cortex in conscious visual perception. J Neurosci. 2011 Jan 5;31(1):64-9. PubMed PMID: 21209190; PubMed Central PMCID: PMC3079255.


Tan, M.K.*, Lim, H.J.*, Harper, J.W. (2011). SCFFBXO22 regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. Mol Cell Biol. 2011 Sep 31 (18): 3687-99. Epub 2011 Jul 18. *these authors contributed equally to this work.


Litterman N, Ikeuchi Y, Gallardo G, O'Connell BC, Sowa ME, Gygi SP, Harper JW, Bonni A. An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. PLoS Biol. 2011 May;9(5):e1001060. Epub 2011 May 10. PubMed PMID: 21572988; PubMed Central PMCID: PMC3091842.


Bian X, Klemm RW, Liu TY, Zhang M, Sun S, Sui X, Liu X, Rapoport TA, Hu J. Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3976-81. doi: 10.1073/pnas.1101643108. Epub 2011 Feb 22. PMID: 21368113 PMCID: PMC3054032 read article


Viswanathan J, Haapasalo A, Böttcher C, Miettinen R, Kurkinen KM, Lu A, Thomas A, Maynard CJ, Romano D, Hyman BT, Berezovska O, Bertram L, Soininen H, Dantuma NP, Tanzi RE, Hiltunen M. Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation. Traffic. 2011 Mar;12(3):330-48. doi: 10.1111/j.1600-0854.2010.01149.x. Epub 2011 Jan 7. PubMed PMID: 21143716; PubMed Central PMCID: PMC3050036.


Tanner GR, Lutas A, Martínez-François JR, Yellen G. Single K ATP channel opening in response to action potential firing in mouse dentate granule neurons. J Neurosci. 2011 Jun 8;31(23):8689-96. doi: 10.1523/JNEUROSCI.5951-10.2011. PMID: 21653873 PMCID: PMC3133530. read article


Manne J, Maciag K. Neglected tropical diseases and the HIV prevention agenda. Lancet. 2011 Dec 17;378(9809):2069-70. doi: 10.1016/S0140-6736(11)61897-7. PMID: 22177509


Layre E, Sweet L, Hong S, Madigan CA, Desjardins D, Young DC, Cheng TY, Annand JW, Kim K, Shamputa IC, McConnell MJ, Debono CA, Behar SM, Minnaard AJ, Murray M, Barry CE 3rd, Matsunaga I, Moody DB. A comparative lipidomics platform for chemotaxonomic analysis of Mycobacterium tuberculosis. Chem Biol. 2011 Dec 23;18(12):1537-49. PubMed PMID: 22195556.


Huang S, Cheng TY, Young DC, Layre E, Madigan CA, Shires J, Cerundolo V, Altman JD, Moody DB. Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19335-40. Epub 2011 Nov 15. PubMed PMID: 22087000; PubMed Central PMCID: PMC3228429.


Magnotti LM, Goodenough DA, Paul DL. Functional heterotypic interactions between astrocyte and oligodendrocyte connexins. Glia. 2011 Jan;59(1):26-34. PMID: 21046554. PMCID: PMC3022368.


Magnotti LM, Goodenough DA, Paul DL. Deletion of oligodendrocyte Cx32 and astrocyte Cx43 causes white matter vacuolation, astrocyte loss and early mortality. Glia. 2011 Jul;59(7):1064-74. doi: 10.1002/glia.21179. Epub 2011 May 2. PubMed PMID: 21538560; PubMed Central PMCID: PMC3094483.


Lukacs-Kornek V, Malhotra D, Fletcher AL, Acton SE, Elpek KG, Tayalia P, Collier AR, Turley SJ. Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes. Nat Immunol. 2011 Sep 18;12(11):1096-104. doi: 10.1038/ni.2112. PMID: 21926986 PMCID: PMC3457791 read article


Elpek KG, Bellemare-Pelletier A, Malhotra D, Reynoso ED, Lukacs-Kornek V, DeKruyff RH, Turley SJ. Lymphoid organ-resident dendritic cells exhibit unique transcriptional fingerprints based on subset and site. PLoS One. 2011;6(8):e23921. doi: 10.1371/journal.pone.0023921. Epub 2011 Aug 19. PMID: 21886840 PMCID: PMC3158776 read article


Fletcher AL, Malhotra D, Acton SE, Lukacs-Kornek V, Bellemare-Pelletier A, Curry M, Armant M, Turley SJ. Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cells. Front Immunol. 2011 Sep 12;2:35. doi: 10.3389/fimmu.2011.00035. eCollection 2011. PMID: 22566825 PMCID: PMC3342056 read article


Fletcher AL, Malhotra D, Turley SJ. Lymph node stroma broaden the peripheral tolerance paradigm. Trends Immunol. 2011 Jan;32(1):12-8. doi: 10.1016/j.it.2010.11.002. Epub 2010 Dec 10. PMID: 21147035 PMCID: PMC3163075 read article


De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, Macleod KF, Cichowski K. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.Cancer Cell. 2011 Sep 13;20(3):400-13. doi: 10.1016/j.ccr.2011.08.014.PMID: 21907929 PMCID: PMC3233475.  read article


Yang DC, Peters NT, Parzych KR, Uehara T, Markovski M, Bernhardt TG. An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):E1052-60. Epub 2011 Oct 17. PubMed PMID: 22006326; PubMed Central PMCID: PMC3215046.


Koh Y, Matreyek KA, Engelman A. Differential sensitivities of retroviruses to integrase strand transfer inhibitors. J Virol. 2011 Apr;85(7):3677-82. doi: 10.1128/JVI.02541-10. Epub 2011 Jan 26. PMID: 21270168 PMCID: PMC3067883 read article


Matreyek KA, Engelman A. The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid. J Virol. 2011 Aug;85(15):7818-27. doi: 10.1128/JVI.00325-11. Epub 2011 May 18. PMID: 21593146 PMCID: PMC3147902 read article


Brown DR, Calpe S, Keszei M, Wang N, McArdel S, Terhorst C, Sharpe AH. Cutting edge: an NK cell-independent role for slamf4 in controlling humoral autoimmunity. J Immunol. 2011 Jul 1;187(1):21-5. doi: 10.4049/jimmunol.1100510. Epub 2011 May 27.PMID 21622868 PMCID: PMC3119727 read article


Cho H, McManus HR, Dove SL, Bernhardt TG. Nucleoid occlusion factor SlmA is a DNA-activated FtsZ polymerization antagonist. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3773-8. doi: 10.1073/pnas.1018674108. Epub 2011 Feb 14. PMID: 21321206 PMCID: PMC3048121 read article


McManus HR, Dove SL. The CgrA and CgrC proteins form a complex that positively regulates cupA fimbrial gene expression in Pseudomonas aeruginosa. J Bacteriol. 2011 Nov;193(22):6152-61. doi: 10.1128/JB.05904-11. Epub 2011 Sep 16. PMID: 21926232 PMCID: PMC3209204 read article


Li S, Moffett HF, Lu J, Werner L, Zhang H, Ritz J, Neuberg D, Wucherpfennig KW, Brown JR, Novina CD. MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells. PLoS One. 2011 Mar 8;6(3):e16956. PubMed PMID: 21408091; PubMed Central PMCID: PMC3050979.


Mullarky E, Mattaini KR, Vander Heiden MG, Cantley LC, Locasale JW. PHGDH amplification and altered glucose metabolism in human melanoma. Pigment Cell Melanoma Res. 2011 Dec;24(6):1112-5. doi: 10.1111/j.1755-148X.2011.00919.x. Epub 2011 Oct 28. PMID: 21981974


Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. PMID: 21804546 PMCID: PMC3677549 read article


Fioravante D, Chu Y, Myoga MH, Leitges M, Regehr WG. Calcium-dependentisoforms of protein kinase C mediate posttetanic potentiation at the calyx ofHeld. Neuron. 2011 Jun 9;70(5):1005-19. PubMed PMID: 21658591; PubMed Central PMCID: PMC3113702.


Myoga MH, Regehr WG. Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses. J Neurosci. 2011 Apr 6;31(14):5235-43. PubMed PMID: 21471358; PubMed Central PMCID: PMC3089026.


Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG. Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses. J Neurophysiol. 2011 Feb;105(2):958-63. Epub 2010 Nov 17. PubMed PMID: 21084685; PubMed Central PMCID: PMC3059182.


Helman E, Naxerova K, Kohane IS. DNA hypermethylation in lung cancer is targeted at differentiation-associated genes. Oncogene. 2012 Mar 1;31(9):1181-8. doi: 10.1038/onc.2011.307. Epub 2011 Aug 1. PubMed PMID: 21804601.


Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L. PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clin Cancer Res. 2011 Jun 1;17(11):3638-48. Epub 2011 Apr 1. PubMed PMID: 21459800; PubMed Central PMCID: PMC3107920.


Gallegos L, Ng MR, Brugge JS. The myosin-II-responsive focal adhesion proteome: a tour de force? Nat Cell Biol. 2011 Apr;13(4):344-6. doi: 10.1038/ncb0411-344. Epub 2011 Mar 20. PMID: 21460805


Iwanicki MP, Davidowitz RA, Ng MR, Besser A, Muranen T, Merritt M, Danuser G, Ince TA, Brugge JS. Ovarian cancer spheroids use myosin-generated force to clear the mesothelium. Cancer Discov. 2011 Jul;1(2):144-57. doi: 10.1158/2159-8274.CD-11-0010. PMID: 22303516 PMCID: PMC3269166 read article


Shyh-Chang N, Zheng Y, Locasale JW, Cantley LC. Human pluripotent stem cells decouple respiration from energy production. EMBO J. 2011 Dec 14;30(24):4851-2. doi: 10.1038/emboj.2011.436. PMID: 22166995 PMCID: PMC3242981 read article


Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators, Altshuler D, Daley GQ. The Lin28/let-7 axis regulates glucose metabolism. Cell. 2011 Sep 30;147(1):81-94. doi: 10.1016/j.cell.2011.08.033. PMID: 21962509 PMCID: PMC3353524 read article


Oldenburg IA, Ding JB. Cholinergic modulation of synaptic integration and dendritic excitability in the striatum. Curr Opin Neurobiol. 2011 Jun;21(3):425-32. doi: 10.1016/j.conb.2011.04.004. PMID: 21550798 PMCID: PMC3138897 read article


Higley MJ, Gittis AH, Oldenburg IA, Balthasar N, Seal RP, Edwards RH, Lowell BB, Kreitzer AC, Sabatini BL. Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum. PLoS One. 2011 Apr 22;6(4):e19155. doi: 10.1371/journal.pone.0019155. PMID: 21544206 PMCID: PMC3081336 read article


Beier KT, Saunders A, Oldenburg IA, Miyamichi K, Akhtar N, Luo L, Whelan SP, Sabatini B, Cepko CL. Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15414-9. doi: 10.1073/pnas.1110854108. Epub 2011 Aug 8. PMID: 21825165 PMCID: PMC3174680 read article


Olive AJ, Gondek DC, Starnbach MN. CXCR3 and CCR5 are both required for T cell-mediated protection against C. trachomatis infection in the murine genital mucosa. Mucosal Immunol. 2011 Mar;4(2):208-16. doi: 10.1038/mi.2010.58. Epub 2010 Sep 15. PMID: 20844481 PMCID: PMC3010299 read article


Coers J, Gondek DC, Olive AJ, Rohlfing A, Taylor GA, Starnbach MN. Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections. PLoS Pathog. 2011 Jun;7(6):e1001346. doi: 10.1371/journal.ppat.1001346. Epub 2011 Jun 23. PMID: 21731484 PMCID: PMC3121881 read article


Pessach IM, Ordovas-Montanes J, Zhang SY, Casanova JL, Giliani S, Gennery AR, Al-Herz W, Manos PD, Schlaeger TM, Park IH, Rucci F, Agarwal S, Mostoslavsky G, Daley GQ, Notarangelo LD. Induced pluripotent stem cells: A novel frontier in the study of human primary immunodeficiencies. J Allergy Clin Immunol. 2011 Jun;127(6):1400-1407.e4. Epub 2010 Dec 24. PMID: 21185069 PMCID: PMC3081993. read article


Moskwa P, Buffa FM, Pan Y, Panchakshari R, Gottipati P, Muschel RJ, Beech J, Kulshrestha R, Abdelmohsen K, Weinstock DM, Gorospe M, Harris AL, Helleday T, Chowdhury D. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell. 2011 Jan 21;41(2):210-20. Epub 2010 Dec 30. PMID: 21195000 PMCID: PMC3249932 read article


Srikantan S, Abdelmohsen K, Lee EK, Tominaga K, Subaran SS, Kuwano Y, Kulshrestha R, Panchakshari R, Kim HH, Yang X, Martindale JL, Marasa BS, Kim MM, Wersto RP, Indig FE, Chowdhury D, Gorospe M. Translational control of TOP2A influences doxorubicin efficacy. Mol Cell Biol. 2011 Sep;31(18):3790-801. doi: 10.1128/MCB.05639-11. Epub 2011 Jul 18. PMID: 21768308; PMCID: PMC3165726 . read article


Ferrero DM, Lemon JK, Fluegge D, Pashkovski SL, Korzan WJ, Datta SR, Spehr M, Fendt M, Liberles SD. Detection and avoidance of a carnivore odor by prey. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11235-40. doi: 10.1073/pnas.1103317108. Epub 2011 Jun 20. PMID: 21690383 PMCID: PMC3131382 read article


Jiang J, Lazarus MB, Pasquina L, Sliz P, Walker S. A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase. Nat Chem Biol. 2011 Nov 13;8(1):72-7. doi: 10.1038/nchembio.711. PMID: 22082911 PMCID: PMC3241908  read article


Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell. 2011 Nov 23;147(5):1066-79. PubMed PMID: 22118463; PubMed Central PMCID: PMC3227872.


Sharp JA, Plant JJ, Ohsumi TK, Borowsky M, Blower MD. Functional analysis of the microtubule-interacting transcriptome. Mol Biol Cell. 2011 Nov;22(22):4312-23. doi: 10.1091/mbc.E11-07-0629. Epub 2011 Sep 21. PMID: 21937723 PMCID: PMC3216657 read article


Ponce CR, Hunter JN, Pack CC, Lomber SG, Born RT. Contributions of indirect pathways to visual response properties in macaque middle temporal area MT. J Neurosci. 2011 Mar 9;31(10):3894-903. PubMed PMID: 21389244; PubMed Central PMCID: PMC3117290.


Medici D, Potenta S, Kalluri R. Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling. Biochem J. 2011 Aug 1;437(3):515-20. doi: 10.1042/BJ20101500. PMID: 21585337


Puram SV, Riccio A, Koirala S, Ikeuchi Y, Kim AH, Corfas G, Bonni A. A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. Genes Dev. 2011 Dec 15;25(24):2659-73. doi: 10.1101/gad.174060.111. Epub 2011 Dec 1. PMID: 22135323 PMCID: PMC3248686 read article


Puram SV, Kim AH, Ikeuchi Y, Wilson-Grady JT, Merdes A, Gygi SP, Bonni A. A CaMKIIβ signaling pathway at the centrosome regulates dendrite patterning in the brain. Nat Neurosci. 2011 Jul 3;14(8):973-83. doi: 10.1038/nn.2857. PMID: 21725312 PMCID: PMC3391735 read article


Puram SV, Bonni A. Novel functions for the anaphase-promoting complex in neurobiology. Semin Cell Dev Biol. 2011 Aug;22(6):586-94. doi: 10.1016/j.semcdb.2011.03.006. Epub 2011 Mar 23. PMID: 21439392 PMCID: PMC3177029 read article


Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P. Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron. 2011 Feb 24;69(4):763-79. PubMed PMID: 21338885; PubMed Central PMCID: PMC3061282.


Park KS, Liang MC, Raiser DM, Zamponi R, Roach RR, Curtis SJ, Walton Z, Schaffer BE, Roake CM, Zmoos AF, Kriegel C, Wong KK, Sage J, Kim CF. Characterization of the cell of origin for small cell lung cancer. Cell Cycle. 2011 Aug 15;10(16):2806-15. Epub 2011 Aug 15. PMID: 21822053 PMCID: PMC3219544 read article


Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK. In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells. 2011 Nov;29(11):1717-26. doi: 10.1002/stem.718. PubMed PMID: 21898685; PubMed Central PMCID: PMC3285772.


Pattanayak V, Ramirez CL, Joung JK, Liu DR. Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection. Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670. PubMed PMID: 21822273; PubMed Central PMCID: PMC3164905.


White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 2011 Mar 24;471(7339):518-22. doi: 10.1038/nature09882. PMID: 21430780 PMCID: PMC3759979 read article


Manos PD, Ratanasirintrawoot S, Loewer S, Daley GQ, Schlaeger TM. Live-cell immunofluorescence staining of human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2011 Dec;Chapter 1:Unit 1C.12. doi: 10.1002/9780470151808.sc01c12s19. PMID: 22135082


Roberson DP, Binshtok AM, Blasl F, Bean BP, Woolf CJ. Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review. Br J Pharmacol. 2011 Sep;164(1):48-58. doi:10.1111/j.1476-5381.2011.01391.x. PubMed PMID: 21457220; PubMed Central PMCID: PMC3171859. read article


Mitra D, Robinson KC, Fisher DE. Melanoma and viagra: an unexpected connection. Pigment Cell Melanoma Res. 2011 Feb;24(1):16-8.


Coers J, Gondek DC, Olive AJ, Rohlfing A, Taylor GA, Starnbach MN. Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections. PLoS Pathog. 2011 Jun;7(6):e1001346. doi: 10.1371/journal.ppat.1001346. Epub 2011 Jun 23. PMID: 21731484 PMCID: PMC3121881 read article


Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH Jr, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R. Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. Chem Biol. 2011 Dec 23;18(12):1602-10. doi: 10.1016/j.chembiol.2011.09.016. PMID: 22195562 PMCID: PMC3474356 read article


Sillé FC, Martin C, Jayaraman P, Rothchild A, Fortune S , Besra GS, Behar SM, Boes M. Requirement for Invariant chain in macrophages for Mycobacterium tuberculosis replication and CD1d antigen presentation. Infect Immun. 2011 Aug;79(8):3053-63. doi: 10.1128/IAI.01108-10. Epub 2011 May 16. PMID: 21576321 PMCID: PMC3147586 read article


Sillé FC, Martin C, Jayaraman P, Rothchild A, Besra GS, Behar SM, Boes M. Critical role for invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells. Immunol Lett. 2011 Sep 30;139(1-2):33-41. doi: 10.1016/j.imlet.2011.04.012. Epub 2011 May 5. PMID: 21565221 PMCID: PMC3146573 read article


Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 2011 Oct 6;72(1):72-85. PubMed PMID: 21982370; PubMed Central PMCID: PMC3226708.


Jin Y, Chauhan SK, Annan JE, Sage PT, Sharpe AH, Dana R. A novel function for programmed death ligand-1 regulation of angiogenesis. Am J Pathol. 2011 Apr;178(4):1922-9. PMCID: PMC3078456.


Riella LV, Watanabe T, Sage PT, Yang J, Yeung M, Azzi J, Vanguri V, Chandraker A, Sharpe AH, Sayegh MH, Najafian N. Essential role of PDL1 expression on nonhematopoietic donor cells in acquired tolerance to vascularized cardiac allografts. Am J Transplant. 2011 Apr;11(4):832-40.


Soskis M, Salogiannis J, Greenberg M. EphrinBs send mixed messages. NatNeurosci. 2011 Oct 26;14(11):1356-8. doi: 10.1038/nn.2968. PubMed PMID: 22030542. PMC3269007.


San Roman AK, Shivdasani RA. Boundaries, junctions and transitions in the gastrointestinal tract. Exp Cell Res. 2011 Nov 15;317(19):2711-8. doi: 10.1016/j.yexcr.2011.07.011. Epub 2011 Jul 23. PMID: 21802415 PMCID: PMC3210370 read article


Sarkar A, Hochedlinger K. A gutsy way to grow: intestinal stem cells as nutrient sensors. Cell. 2011 Oct 28;147(3):487-9. doi: 10.1016/j.cell.2011.10.006. PMID: 22036555


Arnold K, Sarkar A, Yram MA, Polo JM, Bronson R, Sengupta S, Seandel M, Geijsen N, Hochedlinger K. Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem Cell. 2011 Oct 4;9(4):317-29. doi: 10.1016/j.stem.2011.09.001. PMID: 21982232 PMCID: PMC3538360 read article


Beier KT, Saunders A, Oldenburg IA, Miyamichi K, Akhtar N, Luo L, Whelan SP, Sabatini B, Cepko CL. Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15414-9. doi: 10.1073/pnas.1110854108. Epub 2011 Aug 8. PMID: 21825165 PMCID: PMC3174680 read article


Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, Bergethon K, Shaw AT, Gettinger S, Cosper AK, Akhavanfard S, Heist RS, Temel J, Christensen JG, Wain JC, Lynch TJ, Vernovsky K, Mark EJ, Lanuti M, Iafrate AJ, Mino-Kenudson M, Engelman JA. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med. 2011 Mar 23;3(75):75ra26. doi: 10.1126/scitranslmed.3002003. PMID: 21430269 PMCID: PMC3132801 read article


Yang X, Turke AB, Qi J, Song Y, Rexer BN, Miller TW, Jänne PA, Arteaga CL, Cantley LC, Engelman JA, Asara JM. Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer. Cancer Res. 2011 Sep 15;71(18):5965-75. doi: 10.1158/0008-5472.CAN-11-0445. Epub 2011 Jul 20. PMID: 21775521 PMCID: PMC3209668 read article


Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. J Cell Biol. 2011 Mar 7;192(5):825-38. doi: 10.1083/jcb.201008090. Epub 2011 Feb 28. PMID: 21357747 PMCID: PMC3051819 read article


Kriegel MA, Sefik E, Hill JA, Wu HJ, Benoist C, Mathis D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11548-53. doi: 10.1073/pnas.1108924108. Epub 2011 Jun 27. PMID: 21709219 PMCID: PMC3136249 read article


Shepardson NE, Shankar GM, Selkoe DJ. Cholesterol level and statin use in Alzheimer disease: II. Review of human trials and recommendations. Arch Neurol. 2011 Nov;68(11):1385-92. Review. PubMed PMID: 22084122; PubMed Central PMCID: PMC3248784.


Shepardson NE, Shankar GM, Selkoe DJ. Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies. Arch Neurol. 2011 Oct;68(10):1239-44. Review. PubMed PMID: 21987540; PubMed Central PMCID: PMC3211071.


Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ. Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors. J Neurosci. 2011 May 4;31(18):6627-38. PubMed PMID: 21543591; PubMed Central PMCID: PMC3100898.


Dutt A, Ramos AH, Hammerman PS, Mermel C, Cho J, Sharifnia T, Chande A, Tanaka KE, Stransky N, Greulich H, Gray NS, Meyerson M. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PLoS One. 2011;6(6):e20351. doi: 10.1371/journal.pone.0020351. Epub 2011 Jun 7. PMID: 21666749 PMCID: PMC3110189 read article


Savin T, Kurpios NA, Shyer AE, Florescu P, Liang H, Mahadevan L, Tabin CJ. On the growth and form of the gut. Nature. 2011 Aug 3;476(7358):57-62. doi: 10.1038/nature10277. PMID: 21814276 PMCID: PMC3335276 read article


Zhou F, Sikorski TW, Ficarro SB, Webber JT, Marto JA. Online nanoflow reversed phase-strong anion exchange-reversed phase liquid chromatography-tandem mass spectrometry platform for efficient and in-depth proteome sequence analysis of complex organisms. Anal Chem. 2011 Sep 15;83(18):6996-7005. doi: 10.1021/ac200639v. Epub 2011 Aug 18. PMID: 21851055 PMCID: PMC3196608 read article


Sikorski TW, Ficarro SB, Holik J, Kim T, Rando OJ, Marto JA, Buratowski S. Sub1 and RPA associate with RNA polymerase II at different stages of transcription. Mol Cell. 2011 Nov 4;44(3):397-409. doi: 10.1016/j.molcel.2011.09.013. PMID: 22055186 PMCID: PMC3227220 read article


Broadbent KM, Park D, Wolf AR, Van Tyne D, Sims JS, Ribacke U, Volkman S, Duraisingh M, Wirth D, Sabeti PC, Rinn JL. A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs. Genome Biol. 2011 Jun 20;12(6):R56. doi: 10.1186/gb-2011-12-6-r56.PMID: 21689454PMCID: PMC3218844 read article


Chevalier MF, Jülg B, Pyo A, Flanders M, Ranasinghe S, Soghoian DZ, Kwon DS, Rychert J, Lian J, Muller MI, Cutler S, McAndrew E, Jessen H, Pereyra F, Rosenberg ES, Altfeld M, Walker BD, Streeck H. HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function. J Virol. 2011 Jan;85(2):733-41. doi: 10.1128/JVI.02030-10. Epub 2010 Nov 3. PMID: 21047960 PMCID: PMC3020027 read article


Smith SE, Zhou YD, Zhang G, Jin Z, Stoppel DC, Anderson MP. Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice. Sci Transl Med. 2011 Oct 5;3(103):103ra97. doi: 10.1126/scitranslmed.3002627. PMID: 21974935 PMCID: PMC3356696 read article


Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell. 2011 Feb 4;8(2):200-13. PMID: 21295276. PMCID: PMC313431.


Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, Agarwal S, Rao A. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature. 2011 May 19;473(7347):394-7. Epub 2011 May 8. PMID: 21552279. PMCID: PMC3124347.


Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W. mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030. PMID: 22017875 PMCID: PMC3229299 read article


Tan MK, Lim HJ, Harper JW. SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. Mol Cell Biol. 2011 Sep;31(18):3687-99. doi: 10.1128/MCB.05746-11. Epub 2011 Jul 18. PMID: 21768309 PMCID: PMC3165736 read article


Isogai Y, Si S, Pont-Lezica L, Tan T, Kapoor V, Murthy VN, Dulac C. Molecular organization of vomeronasal chemoreception. Nature. 2011 Sep 21;478(7368):241-5. doi: 10.1038/nature10437. PMID: 21937988 PMCID: PMC3192931 read article


Tanner GR, Lutas A, Martínez-François JR, Yellen G. Single K ATP channelopening in response to action potential firing in mouse dentate granule neurons. J Neurosci. 2011 Jun 8;31(23):8689-96. PubMed PMID: 21653873; PubMed Central PMCID: PMC3133530.


Tanner NA, Tolun G, Loparo JJ, Jergic S, Griffith JD, Dixon NE, van Oijen AM. E. coli DNA replication in the absence of free β clamps. EMBO J. 2011 May 4;30(9):1830-40. doi: 10.1038/emboj.2011.84. Epub 2011 Mar 25. PMID: 21441898 PMCID: PMC3101994 read article


Taylor AM, Zon LI. Modeling Diamond Blackfan anemia in the zebrafish. Semin Hematol. 2011 Apr;48(2):81-8. doi: 10.1053/j.seminhematol.2011.02.002. PMID: 21435504


Lal A, Thomas MP, Altschuler G, Navarro F, O'Day E, Li XL, Concepcion C, Han YC, Thiery J, Rajani DK, Deutsch A, Hofmann O, Ventura A, Hide W, Lieberman J. Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling. PLoS Genet. 2011 Nov;7(11):e1002363. doi: 10.1371/journal.pgen.1002363. Epub 2011 Nov 10. PMID: 22102825 PMCID: PMC3213160 read article


Cronican JJ, Beier KT, Davis TN, Tseng JC, Li W, Thompson DB, Shih AF, May EM, Cepko CL, Kung AL, Zhou Q, Liu DR. A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo. Chem Biol. 2011 Jul 29;18(7):833-8. doi: 10.1016/j.chembiol.2011.07.003. PMID: 21802004 PMCID: PMC3154086 read article


Tischfield MA, Cederquist GY, Gupta ML Jr, Engle EC. Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations. Curr Opin Genet Dev. 2011 Jun;21(3):286-94. Epub 2011 Feb 1. Review. PubMed PMID: 21292473; PubMed Central PMCID: PMC3100401.


Tse JC, Kalluri R. Waking up dormant tumors. Breast Cancer Res. 2011 Jun 10;13(3):310. doi: 10.1186/bcr2872. PMID: 21672272 PMCID: PMC3218930 read article


Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. J Cell Biol. 2011 Mar 7;192(5):825-38. doi: 10.1083/jcb.201008090. Epub 2011 Feb 28. PMID: 21357747 PMCID: PMC3051819 read article


Smith KS, Meloni EG, Myers KMM, Van't Veer A, Carlezon WA Jr., and Rudolph U. Reduction of fear-potentiated startle by chlordiazepoxide in C57BL/6J mice. Psychopharmocology. 2011 Feb;213(4):697-706. PMCID: PMC3056161.


Muschamp JW, Van't Veer A, Parsegian A, Gallo MS, Chen M, Neve RL, Meloni EG, and Carlezon WA Jr. Activation of CREB in the nucleus accumbens shell produces anhedonia and resistance to extinction of fear in rats. J Neurosci. 2011 Feb 23;31(8):3095-103. PMCID: PMC3096840.


Muschamp JW, Van't Veer A, Carlezon WA Jr. Tracking down the molecular substrates of stress: New roles for p38a MAPK and kappa-opioid receptors. Neuron. 2011 Aug 11;71(3):383-5. PMCID: PMC3155977.


Vander Lugt B, Beck ZT, Fuhlbrigge RC, Hacohen N, Campbell JJ, Boes M. TGF-β Suppresses β-Catenin-Dependent Tolerogenic Activation Program in Dendritic Cells. PLoS One. 2011;6(5):e20099. Epub 2011 May 20. PMID: 21625453. PMCID: PMC3098869


Ni Chonghaile T, Sarosiek KA, Vo TT, Ryan JA, Tammareddi A, Moore Vdel G, Deng J, Anderson KC, Richardson P, Tai YT, Mitsiades CS, Matulonis UA, Drapkin R, Stone R, Deangelo DJ, McConkey DJ, Sallan SE, Silverman L, Hirsch MS, Carrasco DR, Letai A. Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. Science. 2011 Nov 25;334(6059):1129-33. doi: 10.1126/science.1206727. Epub 2011 Oct 27. PMID: 22033517 PMCID: PMC3280949 read article


Vong S, Kalluri R. The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis. Genes Cancer. 2011 Dec;2(12):1139-45. doi: 10.1177/1947601911423940. PMID: 22866205 PMCID: PMC3411128 read article


Camp AH, Wang AF, Losick R. A small protein required for the switch from {sigma}F to {sigma}G during sporulation in Bacillus subtilis.J Bacteriol. 2011 Jan;193(1):116-24. doi: 10.1128/JB.00949-10. Epub 2010 Oct 29. PMID: 21037003 PMCID: PMC3019954 read article


Wang AY, Cohen JY. EMBO Conference Series on the Assembly and Function of Neuronal Circuits. Neural Syst Circuits. 2011 Oct 27;1(1):15. PubMed PMID: 22329922; PubMed Central PMCID: PMC3278469.


Wardwell LH, Huttenhower C, Garrett WS. Current concepts of the intestinal microbiota and the pathogenesis of infection. Curr Infect Dis Rep. 2011 Feb;13(1):28-34. doi: 10.1007/s11908-010-0147-7. PMID: 21308452 PMCID: PMC3077078 read article


Akten B, Kye MJ, Hao le T, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M. Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10337-42. doi: 10.1073/pnas.1104928108. Epub 2011 Jun 7. PMID: 21652774 PMCID: PMC3121858 read article


Wheeler LA, Trifonova R, Vrbanac V, Basar E, McKernan S, Xu Z, Seung E, Deruaz M, Dudek T, Einarsson JI, Yang L, Allen TM, Luster AD, Tager AM, Dykxhoorn DM, Lieberman J. Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras. J Clin Invest. 2011 Jun 1;121(6):2401-12. doi: 10.1172/JCI45876. Epub 2011 May 16. PubMed PMID: 21576818; PubMed Central PMCID: PMC3104760.


Yan N, O'Day E, Wheeler LA, Engelman A, Lieberman J. HIV DNA is heavily uracilated, which protects it from autointegration. Proc Natl Acad Sci U S A. 2011 May 31;108(22):9244-9. Epub 2011 May 16. PubMed PMID: 21576478; PubMed Central PMCID: PMC3107311.


Gonzalez SF, Degn SE, Pitcher LA, Woodruff M, Heesters BA, Carroll MC. Trafficking of B cell antigen in lymph nodes. Annu Rev Immunol. 2011;29:215-33. doi: 10.1146/annurev-immunol-031210-101255. PMID: 21219172


Woodworth JS, Shin D, Volman M, Nunes-Alves C, Fortune SM, Behar SM. Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. J Immunol. 2011 Feb 1;186(3):1627-37. Epub 2010 Dec 22. PubMed PMID: 21178003; PubMed Central PMCID: PMC3133636.


Wu MP, Gussoni E. Carbamylated erythropoietin does not alleviate signs of dystrophy in mdx mice. Muscle Nerve. 2011 Jan;43(1):88-93. doi: 10.1002/mus.21785. PMID: 21171099 PMCID: PMC3057654 read article


Yang K, Moldovan GL, Vinciguerra P, Murai J, Takeda S, D'Andrea AD. Regulation of the Fanconi anemia pathway by a SUMO-like delivery network. Genes Dev. 2011 Sep 1;25(17):1847-58. PubMed PMID: 21896657; PubMed Central PMCID: PMC3175720.


Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD. The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. Mol Cell Biol. 2011 Jun;31(12):2462-9. Epub 2011 Apr 11. PubMed PMID: 21482670; PubMed Central PMCID: PMC3133424.


Loh YH, Yang L, Yang JC, Li H, Collins JJ, Daley GQ. Genomic approaches to deconstruct pluripotency. Annu Rev Genomics Hum Genet. 2011;12:165-85. doi: 10.1146/annurev-genom-082410-101506. PMID: 21801025 PMCID: PMC3652340  read article


Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 2011 Mar 10;69(5):893-905. doi: 10.1016/j.neuron.2011.01.023. PMID: 21382550 PMCID: PMC3085909 read article


Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell. 2011 Feb 4;144(3):353-63. PMCID: PMC3065114.


Ise W, Kohyama M, Schraml BU, Zhang T, Schwer B, Basu U, Alt FW, Tang J, Oltz EM, Murphy TL, Murphy KM. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nature Immunology. 2011 May 15. PMCID: PMC3117275.


top

2010


Abraira VE, Satoh T, Fekete DM, Goodrich LV. Vertebrate Lrig3-ErbBinteractions occur in vitro but are unlikely to play a role in Lrig3-dependentinner ear morphogenesis. PLoS One. 2010 Feb 1;5(2):e8981. PubMed PMID: 20126551; PubMed Central PMCID: PMC2813878.


Chou DM, Adamson B, Dephoure NE, Tan X, Nottke AC, Hurov KE, Gygi SP, Colaiácovo MP, Elledge SJ. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18475-80. doi: 10.1073/pnas.1012946107. Epub 2010 Oct 11. PMID: 20937877 PMCID: PMC2972950 read article


O'Connell BC, Adamson B, Lydeard JR, Sowa ME, Ciccia A, Bredemeyer AL, Schlabach M, Gygi SP, Elledge SJ, Harper JW. A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability. Mol Cell. 2010 Nov 24;40(4):645-57. doi: 10.1016/j.molcel.2010.10.022. Epub 2010 Nov 4. PMID: 21055985 PMCID: PMC3006237 read article


Agapakis CM, Silver PA. Modular electron transfer circuits for synthetic biology: insulation of an engineered biohydrogen pathway. Bioeng Bugs. 2010 Nov-Dec;1(6):413-8. doi: 10.4161/bbug.1.6.12462. PMID: 21468209 PMCID: PMC3056092 read article


Agapakis CM, Ducat DC, Boyle PM, Wintermute EH, Way JC, Silver PA. Insulation of a synthetic hydrogen metabolism circuit in bacteria. J Biol Eng. 2010 Feb 25;4:3. doi: 10.1186/1754-1611-4-3. PMID: 20184755 PMCID: PMC2847965 read article


Albacker LA, Karisola P, Chang YJ, Umetsu SE, Zhou M, Akbari O, Kobayashi N, Baumgarth N, Freeman GJ, Umetsu DT, DeKruyff RH. (2010) TIM-4, a Receptor for Phosphatidylserine, Controls Adaptive Immunity by Regulating the Removal of Antigen-Specific T Cells. Journal of Immunology. 185(11):6839-49. PMID: 21037090 PMCID: PMC3153437


Chang YJ, Kim HY, Albacker LA, Lee HH, Baumgarth N, Akira S, Savage PB, Endo S, Yamamura T, Maaskant J, Kitano N, Singh A, Bhatt A, Besra GS, van den Elzen P, Appelmelk B, Franck RW, Chen G, DeKruyff RH, Shimamura M, Illarionov P, Umetsu DT. Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity. J Clin Invest. 2011 Jan 4;121(1):57-69. doi: 10.1172/JCI44845. Epub 2010 Dec 13. PMID: 21157038 PMCID: PMC3007162


Dhawale AK, Hagiwara A, Bhalla US, Murthy VN, Albeanu DF. Non-redundant odor coding by sister mitral cells revealed by light addressable glomeruli in the mouse. Nat Neurosci. 2010 Nov;13(11):1404-12. Epub 2010 Oct 17. PubMed PMID: 20953197; PubMed Central PMCID: PMC3208311.


Alpert MD, Rahmberg AR, Neidermyer W, Ng SK, Carville A, Camp JV, Wilson RL, Piatak M Jr, Mansfield KG, Li W, Miller CJ, Lifson JD, Kozlowski PA, Evans DT. Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challenge. J Virol. 2010 Oct;84(20):10748-64. Epub 2010 Aug 11. PMID: 20702641 PMCID: PMC2950576 read article


Giallourakis CC, Franklin A, Guo C, Cheng HL, Yoon HS, Gallagher M, Perlot T, Andzelm M, Murphy AJ, Macdonald LE, Yancopoulos GD, Alt FW. Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22207-12. Epub 2010 Dec 1. PubMed PMID: 21123744; PubMed Central PMCID: PMC3009784. read article


Liu H, Chi AW, Arnett KL, Chiang MY, Xu L, Shestova O, Wang H, Li YM, Bhandoola A, Aster JC, Blacklow SC, Pear WS. Notch dimerization is required for leukemogenesis and T-cell development. Genes Dev. 2010 Nov 1;24(21):2395-407. Epub 2010 Oct 8. PubMed PMID: 20935071; PubMed Central PMCID: PMC2964750.


Arnett KL, Hass M, McArthur DG, Ilagan MX, Aster JC, Kopan R, Blacklow SC. Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nat Struct Mol Biol. 2010 Nov;17(11):1312-7. Epub 2010 Oct 24. PubMed PMID: 20972443; PubMed Central PMCID: PMC3024583.


Miller CL, Arnold MM, Broering TJ, Hastings CE, Nibert ML. Localization of mammalian orthoreovirus proteins to cytoplasmic factory-like structures via nonoverlapping regions of microNS. J Virol. 2010 Jan;84(2):867-82. Epub 2009 Nov 4. PMID: 19889754 PMCID: PMC2798337 read article


Whited JL, Lehoczky JA, Austin CA, Tabin CJ. Dynamic expression of two thrombospondins during axolotl limb regeneration. Dev Dyn. 2011 May;240(5):1249-58. doi: 10.1002/dvdy.22548. Epub 2011 Feb 1. PMID: 21360624 PMCID: PMC3081376 read article


Hellman NE, Liu Y, Merkel E, Austin C, Le Corre S, Beier DR, Sun Z, Sharma N, Yoder BK, Drummond IA. The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18499-504. doi: 10.1073/pnas.1005998107. Epub 2010 Oct 11. PMID: 20937855 PMCID: PMC2972951 read article


Ching MS, Shen Y, Tan WH, Jeste SS, Morrow EM, Chen X, Mukaddes NM, Yoo SY, Hanson E, Hundley R, Austin C, Becker RE, Berry GT, Driscoll K, Engle EC, Friedman S, Gusella JF, Hisama FM, Irons MB, Lafiosca T, LeClair E, Miller DT, Neessen M, Picker JD, Rappaport L, Rooney CM, Sarco DP, Stoler JM, Walsh CA, Wolff RR, Zhang T, Nasir RH, Wu BL; Children's Hospital Boston Genotype Phenotype Study Group. Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):937-47. doi: 10.1002/ajmg.b.31063. PMID: 20468056 PMCID: PMC3001124 read article


Kim S, Lehtinen MK, Sessa A, Zappaterra MW, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantia AS, Broccoli V, Walsh CA. The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 2010 Apr 15;66(1):69-84. doi: 10.1016/j.neuron.2010.03.019. PMID: 20399730 PMCID: PMC2872122 read article


Barker BR, Gladstone MN, Gillard GO, Panas MW, Letvin NL. Critical role for IL-21 in both primary and memory anti-viral CD8+ T cell responses. European Journal of Immunology, 2010; 40(11):3085-96. PMCID: PMC3119210.


Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villén J, Haas W, Sowa ME, Gygi SP. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89. doi: 10.1016/j.cell.2010.12.001. PMID: 21183079 PMCID: PMC3035969 read article


Aguiar M, Haas W, Beausoleil SA, Rush J, Gygi SP. Gas-phase rearrangements do not affect site localization reliability in phosphoproteomics data sets. J Proteome Res. 2010 Jun 4;9(6):3103-7. doi: 10.1021/pr1000225. PMID: 20377248 PMCID: PMC2912977 read article


Cronican JJ, Thompson DB, Beier KT, McNaughton BR, Cepko CL, Liu DR. Potent delivery of functional proteins into Mammalian cells in vitro and in vivo using a supercharged protein. ACS Chem Biol. 2010 Aug 20;5(8):747-52. PubMed PMID: 20545362; PubMed Central PMCID: PMC2924640.


Rosen AM, Stevens B. The role of the classical complement cascade in synapse loss during development and glaucoma. Adv Exp Med Biol. 2010;703:75-93. Review. PubMed PMID: 20711708.


Bilimoria PM, de la Torre-Ubieta L, Ikeuchi Y, Becker EB, Reiner O, Bonni A. AJIP3-regulated GSK3β/DCX signaling pathway restricts axon branching. J Neurosci. 2010 Dec 15;30(50):16766-76. PubMed PMID: 21159948.


Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, Flavell SW, Kim TK, Griffith EC, Waldon Z, Maehr R, Ploegh HL, Chowdhury S, Worley PF, Steen J, Greenberg ME. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell. 2010 Mar 5;140(5):704-16. PubMed PMID: 20211139; PubMed Central PMCID: PMC2843143.


Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW. Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3040-5. Epub 2010 Feb 1. PubMed PMID: 20133637; PubMed Central PMCID: PMC2840363.


Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3034-9. Epub 2010 Jan 25. PubMed PMID: 20133803; PubMed Central PMCID: PMC2840344.


Zhang Y, Gostissa M, Hildebrand DG, Becker MS, Boboila C, Chiarle R, Lewis S, Alt FW. The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv Immunol. 2010;106:93-133. Review. PubMed PMID: 20728025; PubMed Central PMCID: PMC3073861.


Boboila C, Yan C, Wesemann DR, Jankovic M, Wang JH, Manis J, Nussenzweig A, Nussenzweig M, Alt FW. Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. J Exp Med. 2010 Feb 15;207(2):417-27. doi: 10.1084/jem.20092449. Epub 2010 Feb 8. PMID: 20142431 PMCID: PMC2822597 read article


Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW. Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3040-5. doi: 10.1073/pnas.0915072107. Epub 2010 Feb 1. PMID: 20133637 PMCID: PMC2840363 read article


Rowley CF, Boutwell CL, Lee EJ, MacLeod IJ, Ribaudo HJ, Essex M, Lockman S. Ultrasensitive detection of minor drug-resistant variants for HIV after nevirapine exposure using allele-specific PCR: clinical significance. AIDS Res Hum Retroviruses. 2010 Mar;26(3):293-300. doi: 10.1089/aid.2009.0082. PMID: 20334564 PMCID: PMC2864062 read article


Agapakis CM, Ducat DC, Boyle PM, Wintermute EH, Way JC, Silver PA. Insulation of a synthetic hydrogen metabolism circuit in bacteria. J Biol Eng. 2010 Feb 25;4:3. doi: 10.1186/1754-1611-4-3. PMID: 20184755 PMCID: PMC2847965 read article


Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG. Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell. 2010 May 14;141(4):632-44. Epub 2010 Apr 29. PubMed PMID: 20434207; PubMed Central PMCID: PMC2881594.


Brown KE, Freeman GJ, Wherry EJ, Sharpe AH. Role of PD-1 in regulating acute infections. Curr Opin Immunol. 2010 Jun;22(3):397-401. Epub 2010 Apr 27. Review. PubMed PMID: 20427170; PubMed Central PMCID: PMC2905659.


Burrill DR, Silver PA. Making cellular memories. Cell. 2010 Jan 8;140(1):13-8. doi: 10.1016/j.cell.2009.12.034. PMID: 20085698 PMCID: PMC2882105 read article


Burrows AE, Smogorzewska A, Elledge SJ. Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14280-5. doi: 10.1073/pnas.1009559107. Epub 2010 Jul 26. PMID: 20660729 PMCID: PMC2922604 read article


Cedeno-Laurent F, Barthel SR, Opperman MJ, Lee DM, Clark RA, Dimitroff CJ. Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation. J Immunol. 2010 Oct 15;185(8):4659-72. Epub 2010 Sep 15. PubMed PMID: 20844192; PubMed Central PMCID:PMC2953643.


Derti A, Cenik C, Kraft P, Roth FP. Absence of evidence for MHC-dependent mate selection within HapMap populations. PLoS Genet. 2010 Apr 29;6(4):e1000925. PubMed PMID: 20442868; PubMed Central PMCID: PMC2861700.


Cenik C, Derti A, Mellor JC, Berriz GF, Roth FP. Genome-wide functional analysis of human 5' untranslated region introns. Genome Biol. 2010;11(3):R29. Epub 2010 Mar 11. PubMed PMID: 20222956; PubMed Central PMCID: PMC2864569.


Ch'ng YH, Reid RC. Cellular imaging of visual cortex reveals the spatial and functional organization of spontaneous activity. Front Integr Neurosci. 2010 Aug 19;4. pii: 20. PubMed PMID: 20941381; PubMed Central PMCID: PMC2952458.


Chao MC, Rubin EJ. Letting sleeping dos lie: does dormancy play a role in tuberculosis? Annu Rev Microbiol. 2010;64:293-311. Review. PubMed PMID: 20825351.


Hett EC, Chao MC, Rubin EJ. Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria. PLoS Pathog. 2010 Jul 29;6(7):e1001020. PubMed PMID: 20686708; PubMed Central PMCID: PMC2912383.


Chen AC, Guo LY, Ostaszewski BL, Selkoe DJ, LaVoie MJ. Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates. J Biol Chem. 2010 Apr 9;285(15):11378-91. Epub 2010 Feb 9. PubMed PMID: 20145246; PubMed Central PMCID: PMC2857016.


Chiang CW, Gajdos ZK, Korn JM, Kuruvilla FG, Butler JL, Hackett R, Guiducci C, Nguyen TT, Wilks R, Forrester T, Haiman CA, Henderson KD, Le Marchand L, Henderson BE, Palmert MR, McKenzie CA, Lyon HN, Cooper RS, Zhu X, Hirschhorn JN. Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples. PLoS Genet. 2010 Mar 5;6(3):e1000866. PubMed PMID: 20221249; PubMed Central PMCID: PMC2832667.


Kang SJ, Chiang CW, Palmer CD, Tayo BO, Lettre G, Butler JL, Hackett R, Adeyemo AA, Guiducci C, Berzins I, Nguyen TT, Feng T, Luke A, Shriner D, Ardlie K, Rotimi C, Wilks R, Forrester T, McKenzie CA, Lyon HN, Cooper RS, Zhu X, Hirschhorn JN. Genome-wide association of anthropometric traits in African- and African-derived populations. Hum Mol Genet. 2010 Jul 1;19(13):2725-38. Epub 2010 Apr 16. PubMed PMID: 20400458; PubMed Central PMCID: PMC2883343.


Haas MS, Alicot EM, Schuerpf F, Chiu I, Li J, Moore FD, Carroll MC. Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction. Cardiovasc Res. 2010 Sep 1;87(4):618-27. Epub 2010 May 11. PMID: 20462867. PMCID: PMC2920809.


Nowak RJ, Cuny GD, Choi S, Lansbury PT, Ray SS. Improving binding specificity of pharmacological chaperones that target mutant superoxide dismutase-1 linked to familial amyotrophic lateral sclerosis using computational methods. J Med Chem. 2010 Apr 8;53(7):2709-18. PubMed PMID: 20232802.


Prisic S, Dankwa S, Schwartz D, Chou MF, Locasale JW, Kang CM, Bemis G, Church GM, Steen H, Husson RN. Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7521-6. Epub 2010 Apr 5. PubMed PMID: 20368441.


Christofferson DE, Yuan J. Necroptosis as an alternative form of programmed cell death. Curr Opin Cell Biol. 2010 Apr;22(2):263-8. doi: 10.1016/j.ceb.2009.12.003. Epub 2010 Jan 4. PMID: 20045303 PMCID: PMC2854308 read article


Christofferson DE, Yuan J. Cyclophilin A release as a biomarker of necrotic cell death. Cell Death Differ. 2010 Dec;17(12):1942-3. doi: 10.1038/cdd.2010.123. Epub 2010 Oct 8. PMID: 20930851 PMCID: PMC2981659 read article


Zhang H, Zhang X, Clark E, Mulcahey M, Huang S, Shi YG. TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine. Cell Res. 2010 Dec;20(12):1390-3. doi: 10.1038/cr.2010.156. Epub 2010 Nov 16. PMID: 21079648


Colodner KJ, Feany MB. Glial fibrillary tangles and JAK/STAT-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy. J Neurosci. 2010 Dec 1;30(48):16102-13. PubMed PMID: 21123557. PubMed Central PMCID: PMC3073608.


Beriou G, Bradshaw EM, Lozano E, Costantino CM, Hastings WD, Orban T, Elyaman W, Khoury SJ, Kuchroo VK, Baecher-Allan C, Hafler DA. TGF-beta induces IL-9 production from human Th17 cells. J Immunol. 2010 Jul 1;185(1):46-54. Epub 2010 May 24. PubMed PMID: 20498357; PubMed Central PMCID: PMC2936106.


Sakaguchi S, Miyara M, Costantino CM, Hafler DA. FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol. 2010 Jul;10(7):490-500. Epub 2010 Jun 18. Review. PubMed PMID: 20559327.


Curtis SJ, Sinkevicius KW, Li D, Lau AN, Roach RR, Zamponi R, Woolfenden AE, Kirsch DG, Wong KK, Kim CF. Primary tumor genotype is an important determinant in identification of lung cancer propagating cells. Cell Stem Cell. 2010 Jul 2;7(1):127-33. PubMed PMID: 20621056; PubMed Central PMCID: PMC2908996.


Cury KM, Uchida N. Robust odor coding via inhalation-coupled transient activity in the mammalian olfactory bulb. Neuron. 2010 Nov 4;68(3):570-85. PubMed PMID: 21040855.


de la Torre-Ubieta L, Gaudillière B, Yang Y, Ikeuchi Y, Yamada T, DiBacco S, Stegmüller J, Schüller U, Salih DA, Rowitch D, Brunet A, Bonni A. A FOXO-Pak1 transcriptional pathway controls neuronal polarity. Genes Dev. 2010 Apr 15;24(8):799-813. PubMed PMID: 20395366; PubMed Central PMCID: PMC2854394.


Tu C, Ortega-Cava CF, Winograd P, Stanton MJ, Reddi AL, Dodge I, Arya R, Dimri M, Clubb RJ, Naramura M, Wagner KU, Band V, Band H. Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16107-12. Epub 2010 Aug 30. PubMed PMID: 20805499; PubMed Central PMCID: PMC2941294.


Dougan ML, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. J Exp Med. 2010 Sep 27;207(10):2195-206. Epub 2010 Sep 13. PMID: 20837698


Zeissig S, Dougan SK, Barral DC, Junker Y, Chen Z, Kaser A, Ho M, Mandel H, McIntyre A, Kennedy SM, Painter GF, Veerapen N, Besra GS, Cerundolo V, Yue S, Beladi S, Behar SM, Chen X, Gumperz JE, Breckpot K, Raper A, Baer A, Exley MA, Hegele RA, Cuchel M, Rader DJ, Davidson NO, Blumberg RS. Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. J Clin Invest. 2010 Aug 2;120(8):2889-99. doi: 10.1172/JCI42703. Epub 2010 Jul 1. PubMed PMID: 20592474; PubMed Central PMCID: PMC2912200.


Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. J Exp Med. 2010 Sep 27;207(10):2195-206. Epub 2010 Sep 13. PubMed PMID: 20837698; PubMed Central PMCID: PMC2947073.


Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. J Exp Med. 2010 Sep 27;207(10):2195-206. Epub 2010 Sep 13. PubMed PMID: 20837698; PubMed Central PMCID: PMC2947073.


Dufu K Livingstone MJ, Seebacher J, Gygi SP, Wilson SA, Reed R. ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex. Genes Dev. 2010 Sep 15;24(18):2043-53. doi: 10.1101/gad.1898610. PMID: 20844015 PMCID: PMC2939366 read article


Li W, Schulman S, Dutton RJ, Boyd D, Beckwith J, Rapoport TA. Structure of a bacterial homologue of vitamin K epoxide reductase. Nature. 2010 Jan 28;463(7280):507-12. PubMed PMID: 20110994.


Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ. Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA. Cell Stem Cell. 2010 Sep 29. [Epub ahead of print] PMID: 20888316


Tan CS, Ellis LC, Wüthrich C, Ngo L, Broge TA Jr, Saint-Aubyn J, Miller JS, Koralnik IJ. JC virus latency in the brain and extraneural organs of patients with and without progressive multifocal leukoencephalopathy. J Virol. 2010 Sep;84(18):9200-9. Epub 2010 Jul 7. PubMed PMID: 20610709; PubMed Central PMCID: PMC2937633. read article


Erwin JA, Lee JT. Characterization of X-chromosome inactivation status in human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2010 Feb;Chapter 1:Unit 1B.6. PubMed PMID: 20127856.


Yang W, Cai Q, Lui VW, Everley PA, Kim J, Bhola N, Quesnelle KM, Zetter BR, Steen H, Freeman MR, Grandis JR. Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer. J Proteome Res. 2010 Jun 4;9(6):3073-82. doi: 10.1021/pr901211j. PMID: 20426488 PMCID: PMC3149825 read article


Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, Flavell SW, Kim TK, Griffith EC, Waldon Z, Maehr R, Ploegh HL, Chowdhury S, Worley PF, Steen J, Greenberg ME. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell. 2010 Mar 5;140(5):704-16. PubMed PMID: 20211139; PubMed Central PMCID: PMC2843143.


Chiang CW, Gajdos ZK, Korn JM, Kuruvilla FG, Butler JL, Hackett R, Guiducci C, Nguyen TT, Wilks R, Forrester T, Haiman CA, Henderson KD, Le Marchand L, Henderson BE, Palmert MR, McKenzie CA, Lyon HN, Cooper RS, Zhu X, Hirschhorn JN. Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples. PLoS Genet. 2010 Mar 5;6(3):e1000866. PubMed PMID: 20221249; PubMed Central PMCID: PMC2832667.


Gajdos ZK, Henderson KD, Hirschhorn JN, Palmert MR. Genetic determinants of pubertal timing in the general population. Mol Cell Endocrinol. 2010 Feb 6. [Epub ahead of print] PubMed PMID: 20144687.


Shen J, Gilmore EC, Marshall CA, Haddadin M, Reynolds JJ, Eyaid W, Bodell A, Barry B, Gleason D, Allen K, Ganesh VS, Chang BS, Grix A, Hill RS, Topcu M, Caldecott KW, Barkovich AJ, Walsh CA. Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. Nat Genet. 2010 Mar;42(3):245-9. Epub 2010 Jan 31. PubMed PMID: 20118933; PubMed Central PMCID: PMC2835984.


Mochida GH, Ganesh VS, Felie JM, Gleason D, Hill RS, Clapham KR, Rakiec D, Tan WH, Akawi N, Al-Saffar M, Partlow JN, Tinschert S, Barkovich AJ, Ali B, Al-Gazali L, Walsh CA. A homozygous mutation in the tight-junction protein JAM3 causes hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Am J Hum Genet. 2010 Dec 10;87(6):882-9. PMID: 21109224. PMCID: PMC2997371


Kharas MG, Okabe R, Ganis JJ, Gozo M, Khandan T, Paktinat M, Gilliland DG,Gritsman K. Constitutively active AKT depletes hematopoietic stem cells andinduces leukemia in mice. Blood. 2010 Feb 18;115(7):1406-15. Epub 2009 Dec 14. PubMed PMID: 20008787; PubMed Central PMCID: PMC2826762. read article


Odyniec AN, Barral DC, Garg S, Tatituri RV, Besra GS, Brenner MB. Regulation of CD1 antigen-presenting complex stability. J Biol Chem. 2010 Apr 16;285(16):11937-47. Epub 2010 Feb 4. PMID: 20133943 PMCID: PMC2852931


Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W. Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Mol Cell. 2010 Sep 10;39(5):797-808. doi: 10.1016/j.molcel.2010.08.016. PMID: 20832730 PMCID: PMC2939073 read article


Ge X, Frank CL, Calderon de Anda F, Tsai LH. Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron. 2010 Jan 28;65(2):191-203. PubMed PMID: 20152126; PubMed Central PMCID: PMC2902371.


Marín O, Valiente M, Ge X, Tsai LH. Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol. 2010 Feb;2(2):a001834. Review. PubMed PMID: 20182622; PubMed Central PMCID: PMC2828271.


Singh KK, Ge X, Mao Y, Drane L, Meletis K, Samuels BA, Tsai LH. Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron. 2010 Jul 15;67(1):33-48. PubMed PMID: 20624590; PubMed Central PMCID: PMC2938013.


de Anda FC, Meletis K, Ge X, Rei D, Tsai LH. Centrosome motility is essential for initial axon formation in the neocortex. J Neurosci. 2010 Aug 4;30(31):10391-406. PubMed PMID: 20685982.


Frank CL, Ge X, Xie Z, Zhou Y, Tsai LH. Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. J Biol Chem. 2010 Oct 22;285(43):33324-37. Epub 2010 Aug 19. PubMed PMID: 20724472; PubMed Central PMCID: PMC2963346.


Laurent G, German N, Haigis M. SIRT4 enzymatic activity and biological functions. Review. Experimental Medicine. December 2010. (Invited Review Article - Not a peer reviewed article.)


Giessel AJ, Sabatini BL. M1 muscarinic receptors boost synaptic potentials and calcium influx in dendritic spines by inhibiting postsynaptic SK channels.Neuron. 2010 Dec 9;68(5):936-47. PubMed PMID: 21145006; PubMed Central PMCID: PMC3052967.


Noseda R, Kainz V, Jakubowski M, Gooley JJ, Saper CB, Digre K, Burstein R. A neural mechanism for exacerbation of headache by light. Nat Neurosci. 2010 Feb;13(2):239-45. Epub 2010 Jan 10. PubMed PMID: 20062053; PubMed Central PMCID: PMC2818758.


Gouwens NW, Zeberg H, Tsumoto K, Tateno T, Aihara K, Robinson HP. Synchronization of firing in cortical fast-spiking interneurons at gamma frequencies: a phase-resetting analysis. PLoS Comput Biol. 2010 Sep 30;6(9). pii: e1000951. PubMed PMID: 20941393; PubMed Central PMCID: PMC2947988.


Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. IAP inhibitors enhance co-stimulation to promote tumor immunity. J Exp Med. 2010 Sep 27;207(10):2195-206. Epub 2010 Sep 13. PubMed PMID: 20837698; PubMed Central PMCID: PMC2947073. read article


Grassian AR, Schafer ZT, Brugge JS. ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells. J Biol Chem. 2011 Jan 7;286(1):79-90. Epub 2010 Oct 18. PubMed PMID: 20956544; PubMed Central PMCID: PMC3013038.


Greenblatt MB, Shim, JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arathur S, Xie M, Schneider MD, Zhai B, Gygi S, Davis R. Glimcher LH. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.J Clin Invest. 2010 Jul 1; 120(7):2457073.doe: 10. 1172/JCI42285. Epub 2010 Jun 14. doi: 10.1172/JCI42285. PMID: 20551513. PMCID: PMC2898605.


Greenblatt MB, Aliprantis A, Hu B, Glimcher LH. Calcineurin regulates innate antifungal immunity in neutrophils. J Exp Med. 2010 May 10;207(5):923-31. Epub 2010 Apr 26. PMID: 20421389 PMCID: PMC2867274


Greenblatt MB, Shim JH, Glimcher LH. TAK1 mediates BMP signaling in cartilage. Ann N Y Acad Sci. 2010 Mar;1192(1):385-90. PMID: 20392264. PMCID: PMC3096020


Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, Gershon E, Livneh J, Shen PH, Nikolajsen L, Karppinen J, Männikkö M, Kelempisioti A, Goldman D, Maixner W, Geschwind DH, Max MB, Seltzer Z, Woolf CJ. Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain. 2010 Sep;133(9):2519-27. Epub 2010 Aug 18. Erratum in: Brain. 2011 Jul;134(7):2186. Gershon, Edith [added]; Livneh, Jessica [added]. PubMed PMID: 20724292; PubMed Central PMCID: PMC2929335.


Neely GG, Hess A, Costigan M, Keene AC, Goulas S, Langeslag M, Griffin RS, Belfer I, Dai F, Smith SB, Diatchenko L, Gupta V, Xia CP, Amann S, Kreitz S, Heindl-Erdmann C, Wolz S, Ly CV, Arora S, Sarangi R, Dan D, Novatchkova M, Rosenzweig M, Gibson DG, Truong D, Schramek D, Zoranovic T, Cronin SJ, Angjeli B, Brune K, Dietzl G, Maixner W, Meixner A, Thomas W, Pospisilik JA, Alenius M, Kress M, Subramaniam S, Garrity PA, Bellen HJ, Woolf CJ, Penninger JM. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell. 2010 Nov 12;143(4):628-38. PubMed PMID: 21074052; PubMed Central PMCID: PMC3040441.


Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC. Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82. doi: 10.1210/en.2010-0511. Epub 2010 Jul 21. PMID: 20660060 PMCID: PMC2940501 read article


Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S, Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M. Tsc2-Rheb signaling regulates EphA-mediated axon guidance. Nat Neurosci. 2010 Feb;13(2):163-72. Epub 2010 Jan 10. PubMed PMID: 20062052; PubMed Central PMCID: PMC2812631.


Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010 Nov 16;19(5):727-39. doi: 10.1016/j.devcel.2010.10.008. PMID: 21074722 PMCID: PMC3033574 read article


Iannacone M, Moseman EA, Tonti E, Bosurgi L, Junt T, Henrickson SE, Whelan SP, Guidotti LG, von Andrian UH. Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature. 2010 Jun 24;465(7301):1079-83. PMID: 20577213 PMCID: PMC2892812


Boscacci RT, Pfeiffer F, Gollmer K, Sevilla AI, Martin AM, Soriano SF, Natale D, Henrickson S, von Andrian UH, Fukui Y, Mellado M, Deutsch U, Engelhardt B, Stein JV. Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. Blood. 2010 Aug 12;116(6):915-25. Epub 2010 Apr 15. PMID: 20395417. PMCID: PMC3324225


Henrickson SE, DiMarzio EA, Wang Q, Stanford VM, Kasianowicz JJ. Probing single nanometer-scale pores with polymeric molecular rulers. J Chem Phys. 2010 Apr 7;132(13):135101. PMID: 20387958


Textor J, Peixoto A, Henrickson SE, Sinn M, von Andrian UH, Westermann J.Defining the quantitative limits of intravital two-photon lymphocyte tracking.Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12401-6. Epub 2011 Jul 6.PMID:21734152. PMCID: PMC3145739


Herrington TM, Assad JA. Temporal sequence of attentional modulation in the lateral intraparietal area and middle temporal area during rapid covert shifts of attention. J Neurosci. 2010 Mar 3;30(9):3287-96. PubMed PMID: 20203188; PubMed Central PMCID: PMC2854171.


Park B, Spooner E, Houser BL, Strominger JL, Ploegh HL. The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation. J Exp Med. 2010 Aug 30;207(9):2033-41. Epub 2010 Aug 16. PMCID: PMC2931171.


Miyake N, Andrews C, Fan W, He W, Chan WM, Engle EC. CHN1 mutations are not a common cause of sporadic Duane's retraction syndrome. Am J Med Genet A. 2010 Jan;152A(1):215-7. doi: 10.1002/ajmg.a.33168. PMID: 20034095 PMCID: PMC2801889 read article


Tsui JM, Hunter JN, Born RT, Pack CC. The role of V1 surround suppression in MT motion integration. J Neurophysiol. 2010 Jun;103(6):3123-38. Epub 2010 Mar 24. PubMed PMID: 20457860; PubMed Central PMCID: PMC2888240.


Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA. Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication. J Am Chem Soc. 2010 Apr 28;132(16):5880-5. PubMed PMID: 20359213; PubMed Central PMCID: PMC2857888.


Jensen DK, Lal A. Micromanaging senescence. Aging (Albany NY). 2010 Jun;2(6):322-3. PMID: 20603523 PMCID: PMC2919248 read article


Thiery J, Walch M, Jensen DK, Martinvalet D, Lieberman J. Isolation of cytotoxic T cell and NK granules and purification of their effector proteins. Curr Protoc Cell Biol. 2010 Jun;Chapter 3:Unit3.37. doi: 10.1002/0471143030.cb0337s47. PMID: 20521234


Johnson KE, Knipe DM. Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before Jak-1 activation. Virology. 2010 Jan 5;396(1):21-9. Epub 2009 Oct 31. PMID: 19879619 PMCID: PMC2787861 read article


Andermann ML, Kerlin AM, Reid RC. Chronic cellular imaging of mouse visual cortex during operant behavior and passive viewing. Front Cell Neurosci. 2010 Mar 12;4:3. PubMed PMID: 20407583; PubMed Central PMCID: PMC2854571.


Wiig H, Keskin D, Kalluri R. Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biol. 2010 Oct;29(8):645-56. doi: 10.1016/j.matbio.2010.08.001. Epub 2010 Aug 18. PMID: 20727409 PMCID: PMC3992865 read article


Keskin D, Kalluri R. NF-kappaB-induced chromatin remodeling regulates angiogenesis.Blood. 2010 Jul 22;116(3):312-3. doi: 10.1182/blood-2010-03-274316. PMID: 20651081


Khurana V, Elson-Schwab I, Fulga TA, Sharp KA, Loewen CA, Mulkearns E, Tyynelä J, Scherzer CR, Feany MB. Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo. PLoS Genet. 2010 Jul 15;6(7):e1001026. PubMed PMID: 20664788; PubMed Central PMCID: PMC2904797.


Kim IS, Trask SD, Babyonyshev M, Dormitzer PR, Harrison SC. Effect of mutations in VP5 hydrophobic loops on rotavirus cell entry. J Virol. 2010 Jun;84(12):6200-7. Epub 2010 Apr 7. PMID: 20375171 PMCID: PMC2876642 read article


Hamouda AK, Kimm T, Cohen JB. Physostigmine and galanthamine bind in the presence of agonist at the canonical and noncanonical subunit interfaces of a nicotinic acetylcholine receptor. J Neurosci. 2013 Jan 9;33(2):485-94. doi: 10.1523/JNEUROSCI.3483-12.2013. PMID: 23303929 PMCID: PMC3542985 read article


Koh AS, Kingston RE, Benoist C, Mathis D. Global relevance of Aire binding to hypomethylated lysine-4 of histone-3. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13016-21. Epub 2010 Jul 6. PMID: 20615959 PMCID: PMC2919944.


Keebler ME, Deo RC, Surti A, Konieczkowski D, Guiducci C, Burtt N, Buxbaum SG, Sarpong DF, Steffes MW, Wilson JG, Taylor HA, Kathiresan S. Fine-mapping in African Americans of 8 recently discovered genetic loci for plasma lipids: the Jackson Heart Study. Circ Cardiovasc Genet. 2010 Aug;3(4):358-64. doi: 10.1161/CIRCGENETICS.109.914267. Epub 2010 Jun 22. PMID: 20570916 PMCID: PMC3074173 read article


Ghosh S, Koralov SB, Stevanovic I, Sundrud MS, Sasaki Y, Rajewsky K, Rao A, Müller M. Hyperactivation of NFAT1 in T cells attenuates development of murine autoimmune encephalomyelitis. PNAS 2010 Aug 24;107(34):15169-74. PMID: 20696888. PMC2930568.


Higashi-Kovtun ME, Mosca TJ, Dickman DK, Meinertzhagen IA, Schwarz TL. Importin-β11 Regulates Synaptic Phosphorylated Mothers Against Decapentaplegic, and Thereby Influences Synaptic Development and Function at the Drosophila Neuromuscular Junction. Journal of Neuroscience. 2010. 30, 5253-5268. PMCID: PMC2881940.


Rahmeh AA, Schenk AD, Danek EI, Kranzusch PJ, Liang B, Walz T, Whelan SP. Molecular architecture of the vesicular stomatitis virus RNA polymerase. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20075-80. Epub 2010 Nov 1. PMID: 21041632 PMCID: PMC2993402 read article


Kranzusch PJ, Schenk AD, Rahmeh AA, Radoshitzky SR, Bavari S, Walz T, Whelan SP. Assembly of a functional Machupo virus polymerase complex. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20069-74. Epub 2010 Oct 26. PMID: 20978208 PMCID: PMC2993349 read article


Liu W, Li Y, Learn GH, Rudicell RS, Robertson JD, Keele BF, Ndjango JB, Sanz CM, Morgan DB, Locatelli S, Gonder MK, Kranzusch PJ, Walsh PD, Delaporte E, Mpoudi-Ngole E, Georgiev AV, Muller MN, Shaw GM, Peeters M, Sharp PM, Rayner JC, Hahn BH. Origin of the human malaria parasite Plasmodium falciparum in gorillas. Nature. 2010 Sep 23;467(7314):420-5. PMID: 20864995 PMCID: PMC2997044 read article


Radoshitzky SR, Dong L, Chi X, Clester JC, Retterer C, Spurgers K, Kuhn JH, Sandwick S, Ruthel G, Kota K, Boltz D, Warren T, Kranzusch PJ, Whelan SP, Bavari S. Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin. J Virol. 2010 Oct;84(20):10569-80. Epub 2010 Aug 4. PMID: 20686043 PMCID: PMC2950602 read article


Neel C, Etienne L, Li Y, Takehisa J, Rudicell RS, Bass IN, Moudindo J, Mebenga A, Esteban A, Van Heuverswyn F, Liegeois F, Kranzusch PJ, Walsh PD, Sanz CM, Morgan DB, Ndjango JB, Plantier JC, Locatelli S, Gonder MK, Leendertz FH, Boesch C, Todd A, Delaporte E, Mpoudi-Ngole E, Hahn BH, Peeters M. Molecular epidemiology of simian immunodeficiency virus infection in wild-living gorillas. J Virol. 2010 Feb;84(3):1464-76. Epub 2009 Nov 11. PMID: 19906908 PMCID: PMC2812320 read article


Kreslavsky T, Gleimer M, Garbe AI, von Boehmer H. αβ versus γδ fate choice: counting the T-cell lineages at the branch point. Immunol Rev. 2010 Nov;238(1):169-81. doi: 10.1111/j.1600-065X.2010.00947.x. Review. PubMed PMID: 20969592; PubMed Central PMCID: PMC3031133.


Kreslavsky T, Gleimer M, von Boehmer H. Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpoint. Curr Opin Immunol. 2010 Apr;22(2):185-92. Epub 2010 Jan 13. Review. PubMed PMID: 20074925; PubMed Central PMCID: PMC2861550.


Kreslavsky T, von Boehmer H. gammadeltaTCR ligands and lineage commitment. Semin Immunol. 2010 Aug;22(4):214-21. Epub 2010 May 5. Review. PubMed PMID: 20447836; PubMed Central PMCID: PMC2912151.


Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K, Song JJ, Kingston RE, Borowsky M, Lee JT. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell. 2010 Dec 22;40(6):939-53. doi: 10.1016/j.molcel.2010.12.011. PMID: 21172659 PMCID: PMC3021903.  read article


Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW. Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21790-4. doi: 10.1073/pnas.1016306107. Epub 2010 Nov 22. PMID: 21098266 PMCID: PMC3003110.  read article


Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, DeAngelo DJ, Carr SA, Schreiber SL, Golub TR, Ebert BL. Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12617-22. doi: 10.1073/pnas.1006774107. Epub 2010 Jun 28. PMID: 20616024 PMCID: PMC2906581 read article


Kwiatkowski N, Jelluma N, Filippakopoulos P, Soundararajan M, Manak MS, Kwon M, Choi HG, Sim T, Deveraux QL, Rottmann S, Pellman D, Shah JV, Kops GJ, Knapp S, Gray NS. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010 May;6(5):359-68. doi: 10.1038/nchembio.345. Epub 2010 Apr 11. PMID: 20383151 PMCID: PMC2857554 read article


Jelluma N, Dansen TB, Sliedrecht T, Kwiatkowski NP, Kops GJ. Release of Mps1 from kinetochores is crucial for timely anaphase onset. J Cell Biol. 2010 Oct 18;191(2):281-90. doi: 10.1083/jcb.201003038. Epub 2010 Oct 11. PMID: 20937696 PMCID: PMC2958484 read article


Curtis SJ, Sinkevicius KW, Li D, Lau AN, Roach RR, Zamponi R, Woolfenden AE, Kirsch DG, Wong KK, Kim CF. Primary tumor genotype is an important determinant in identification of lung cancer propagating cells. Cell Stem Cell. 2010 Jul 2;7(1):127-33. doi: 10.1016/j.stem.2010.05.021. PMID: 20621056 PMCID: PMC2908996  read article


Mitsdoerffer M, Lee Y, Jäger A, Kim HJ, Korn T, Kolls JK, Cantor H, Bettelli E, Kuchroo VK. Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14292-7. doi: 10.1073/pnas.1009234107. Epub 2010 Jul 26. PMID: 20660725 PMCID: PMC2922571. read article


Kim S, Lehtinen MK, Sessa A, Zappaterra MW, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantia AS, Broccoli V, Walsh CA. The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 2010 Apr 15;66(1):69-84. PubMed PMID: 20399730; PubMed Central PMCID: PMC2872122.
"


Qi, H.H., Sarkissian, M., Hu, G., Wang, Z., Bhattacharjee, A., Gordon, D.B., Gonzales, M., Lan, F., Ongusaha, P.P., Huarte, M., Yaghi, N.K., Lim, H., Garcia, B.A., Brizuela, L., Zhao, K., Roberts, T.M. and Shi, Y. (2010). Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature 466, 503-507.


Liu JJ, Fisher DE. Lighting a path to pigmentation: mechanisms of MITF induction by UV. Pigment Cell Melanoma Res. 2010 Dec;23(6):741-5. doi: 10.1111/j.1755-148X.2010.00775.x. PMID: 20973930


Diebold ML, Koch M, Loeliger E, Cura V, Winston F, Cavarelli J, Romier C. The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26. EMBO J. 2010 Dec 1;29(23):3979-91. doi: 10.1038/emboj.2010.272. Epub 2010 Nov 5. PMID: 21057455 PMCID: PMC3020637 read article


Diebold ML, Loeliger E, Koch M, Winston F, Cavarelli J, Romier C. Noncanonical tandem SH2 enables interaction of elongation factor Spt6 with RNA polymerase II. J Biol Chem. 2010 Dec 3;285(49):38389-98. doi: 10.1074/jbc.M110.146696. Epub 2010 Oct 6. PMID: 20926373 PMCID: PMC2992272 read article


Leisner M, Bleris L, Lohmueller J, Xie Z, Benenson Y. Rationally designed logic integration of regulatory signals in mammalian cells. Nat Nanotechnol. 2010 Sep;5(9):666-70. doi: 10.1038/nnano.2010.135. Epub 2010 Jul 11. PMID: 20622866 PMCID: PMC2934882 read article


Tukachinsky H, Lopez LV, Salic A. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol. 2010 Oct 18;191(2):415-28. doi: 10.1083/jcb.201004108. PMID: 20956384 PMCID: PMC2958481 read article


Mullally A, Lane SW, Ball B, Megerdichian C, Okabe R, Al-Shahrour F, Paktinat M, Haydu JE, Housman E, Lord AM, Wernig G, Kharas MG, Mercher T, Kutok JL, Gilliland DG, Ebert BL. Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells. Cancer Cell. 2010 Jun 15;17(6):584-96. doi: 10.1016/j.ccr.2010.05.015. PMID: 20541703 PMCID: PMC2909585  read article


Young-Pearse TL, Suth S, Luth ES, Sawa A, Selkoe DJ. Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. J Neurosci. 2010 Aug 4;30(31):10431-40. doi: 10.1523/JNEUROSCI.1445-10.2010. PMID: 20685985 PMCID: PMC3018837. read article


Maciag K, Kishore SP. Generic drugs for developing nations. Nat Rev Microbiol. 2010 Jul;8(7):530. doi: 10.1038/nrmicro2345-c1. PMID: 20531275


Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29;143(3):442-55. doi: 10.1016/j.cell.2010.09.038.PMID: 21029865 PMCID: PMC2967209.  read article


Manuel ER, Yeh WW, Balachandran H, Clarke RH, Lifton MA, Letvin NL. Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral control. J Virol. 2010 Dec;84(24):12782-9. Epub 2010 Sep 29. PMID: 20881040 PMCID: PMC3004339 read article


Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29;143(3):442-55. PubMed PMID: 21029865; PubMed Central PMCID: PMC2967209.


Ross SE, Mardinly AR, McCord AE, Zurawski J, Cohen S, Jung C, Hu L, Mok SI, Shah A, Savner EM, Tolias C, Corfas R, Chen S, Inquimbert P, Xu Y, McInnes RR, Rice FL, Corfas G, Ma Q, Woolf CJ, Greenberg ME. Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron. 2010 Mar 25;65(6):886-98. PubMed PMID: 20346763; PubMed Central PMCID: PMC2856621.


Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, Flavell SW, Kim TK, Griffith EC, Waldon Z, Maehr R, Ploegh HL, Chowdhury S, Worley PF, Steen J, Greenberg ME. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell. 2010 Mar 5;140(5):704-16. PubMed PMID: 20211139;


Paradis-Bleau C, Markovski M, Uehara T, Lupoli TJ, Walker S, Kahne DE, Bernhardt TG. Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases. Cell. 2010 Dec 23;143(7):1110-20. PubMed PMID: 21183074; PubMed Central PMCID: PMC3085243.


Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A. The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase. J Virol. 2010 Jan;84(1):397-406. doi: 10.1128/JVI.01899-09. Epub 2009 Oct 21. PMID: 19846519 PMCID: PMC2798409 read article


LeBleu V, Sund M, Sugimoto H, Birrane G, Kanasaki K, Finan E, Miller CA,Gattone VH 2nd, McLaughlin H, Shield CF 3rd, Kalluri R. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IVcollagen network assembly. J Biol Chem. 2010 Dec 31;285(53):41874-85. Epub 2010 Sep 16. PubMed PMID: 20847057; PubMed Central PMCID: PMC3009915.


Min J, Zaslavsky A, Fedele G, McLaughlin SK, Reczek EE, De Raedt T, Guney I, Strochlic DE, Macconaill LE, Beroukhim R, Bronson RT, Ryeom S, Hahn WC, Loda M, Cichowski K. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB. Nat Med. 2010 Mar;16(3):286-94. doi: 10.1038/nm.2100. Epub 2010 Feb 14. PMID: 20154697 PMCID: PMC2903662 read article


Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW. Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3040-5. Epub 2010 Feb 1. PubMed PMID: 20133637. PMCID: PMC2840363.


Holman AG, Mefford ME, O'Connor N, Gabuzda D. HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites. AIDS Res Ther. 2010 Dec 14;7:43. PMID: 21156070 PMCID: PMC3018377 read article


Hellman NE, Liu Y, Merkel E, Austin C, Le Corre S, Beier DR, Sun Z, Sharma N, Yoder BK, Drummond IA. The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18499-504. doi: 10.1073/pnas.1005998107. Epub 2010 Oct 11. PMID: 20937855 PMCID: PMC2972951 read article


Bienvenu F, Jirawatnotai S, Elias JE, Meyer CA, Mizeracka K, Marson A, Frampton GM, Cole MF, Odom DT, Odajima J, Geng Y, Zagozdzon A, Jecrois M, Young RA, Liu XS, Cepko CL, Gygi SP, Sicinski P. Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 2010 Jan 21;463(7279):374-8. doi: 10.1038/nature08684. PMID: 20090754 PMCID: PMC2943587 read article


Mosca TJ, Schwarz TL. Drosophila Importin-α2 is involved in synapse, axon and muscle development. PLoS One. 2010 Dec 6;5(12):e15223. PubMed PMID: 21151903;PubMed Central PMCID: PMC2997784.


Mosca TJ, Schwarz TL. The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development. Nat Neurosci. 2010 Aug;13(8):935-43. Epub 2010 Jul 4. PubMed PMID: 20601947; PubMed Central PMCID: PMC2913881.


Higashi-Kovtun ME, Mosca TJ, Dickman DK, Meinertzhagen IA, Schwarz TL.Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci. 2010 Apr 14;30(15):5253-68. PubMed PMID: 20392948; PubMed Central PMCID: PMC2881940.


Paust S, Gill HS, Wang BZ, Flynn MP, Moseman EA, Senman B, Szczepanik M, Telenti A, Askenase PW, Compans RW, von Andrian UH. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat Immunol. 2010 Dec;11(12):1127-35. Epub 2010 Oct 24. PubMed PMID: 20972432; PubMed Central PMCID: PMC2982944


Bao X, Moseman EA, Saito H, Petryanik B, Thiriot A, Hatakeyama S, Ito Y, Kawashima H, Yamaguchi Y, Lowe JB, von Andrian UH, Fukuda M. Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes. Immunity. 2010 Nov 24;33(5):817-29. PubMed PMID: 21093315; PubMed Central PMCID: PMC2996097


Iannacone M, Moseman EA, Tonti E, Bosurgi L, Junt T, Henrickson SE, Whelan SP, Guidotti LG, von Andrian UH. Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature. 2010 Jun 24;465(7301):1079-83. PubMed PMID: 20577213; PubMed Central PMCID: PMC2892812


Mamo T, Moseman EA, Kolishetti N, Salvador-Morales C, Shi J, Kuritzkes DR,Langer R, von Andrian U, Farokhzad OC. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomedicine (Lond). 2010 Feb;5(2):269-85. Review. PubMed PMID: 20148638; PubMed Central PMCID: PMC2861897


Liang X, Moseman EA, Farrar MA, Bachanova V, Weisdorf DJ, Blazar BR, Chen W. Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. Blood. 2010 Jun 17;115(24):5041-52. Epub 2010 Mar 25. PubMed PMID: 20339095; PubMed Central PMCID: PMC2890142


Surolia I, Pirnie SP, Chellappa V, Taylor KN, Cariappa A, Moya J, Liu H, Bell DW, Driscoll DR, Diederichs S, Haider K, Netravali I, Le S, Elia R, Dow E, Lee A, Freudenberg J, De Jager PL, Chretien Y, Varki A, Macdonald ME, Gillis T, Behrens TW, Bloch D, Collier D, Korzenik J, Podolsky DK, Hafler D, Murali M, Sands B, Stone JH, Gregersen PK, Pillai S. Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Nature. 2010 Jul 8;466(7303):243-7. doi: 10.1038/nature09115. Epub 2010 Jun 16. PMID: 20555325 PMCID: PMC2900412 read article


Yoshida T, Ng SY, Georgopoulos K. Awakening lineage potential by Ikaros-mediated transcriptional priming. Curr Opin Immunol. 2010 Apr;22(2):154-60. Epub 2010 Mar 17. Review. PubMed PMID: 20299195.


Zhu H, Shah S, Shyh-Chang N, Shinoda G, Einhorn WS, Viswanathan SR, Takeuchi A, Grasemann C, Rinn JL, Lopez MF, Hirschhorn JN, Palmert MR, Daley GQ. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet. 2010 Jul;42(7):626-30. doi: 10.1038/ng.593. Epub 2010 May 30. PMID: 20512147 PMCID: PMC3069638 read article


Ni AM, Maunsell JH. Microstimulation reveals limits in detecting different signals from a local cortical region. Curr Biol. 2010 May 11;20(9):824-8. Epub 2010 Apr 8. PubMed PMID: 20381351; PubMed Central PMCID: PMC2879058.


Nielsen CM, Dymecki SM. Sonic hedgehog is required for vascular outgrowth in the hindbrain choroid plexus. Dev Biol. 2010 Apr 15;340(2):430-7. Epub 2010 Feb 1. PubMed PMID: 20123094.


Olsen SR, Bhandawat V, Wilson RI. Divisive normalization in olfactory population codes. Neuron. 2010 Apr 29;66(2):287-99. PubMed PMID: 20435004; PubMed Central PMCID: PMC2866644.


Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman DR, Coffin JM, Hughes SH, Unutmaz D, Engelman A, KewalRamani VN. Flexible use of nuclear import pathways by HIV-1. Cell Host Microbe. 2010 Mar 18;7(3):221-33. doi: 10.1016/j.chom.2010.02.007. PMID: 20227665 PMCID: PMC2841689


Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A. The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase. J Virol. 2010 Jan;84(1):397-406. doi: 10.1128/JVI.01899-09. Epub 2009 Oct 21. PMID: 19846519 PMCID: PMC2798409 read article


Paik EJ, Zon LI. Hematopoietic development in the zebrafish. Int J Dev Biol. 2010;54(6-7):1127-37. doi: 10.1387/ijdb.093042ep. PMID: 20711990


Paik EJ, de Jong JL, Pugach E, Opara P, Zon LI. A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish. 2010 Mar;7(1):61-8. doi: 10.1089/zeb.2009.0643. PMID: 20415644 PMCID: PMC2897134 read article


Barker BR, Gladstone MN, Gillard GO, Panas MW, Letvin NL. Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses..Eur J Immunol. 2010 Nov;40(11):3085-96. doi: 10.1002/eji.200939939. Epub 2010 Oct 27. PMID:21061439. PMCID: PMC3119210.


Puram SV, Kim AH, Bonni A. An old dog learns new tricks: a novel function for Cdc20-APC in dendrite morphogenesis in neurons. Cell Cycle. 2010 Feb 1;9(3):482-5. PMID: 20195072 PMCID: PMC2853878 read article


Fletcher AL, Lukacs-Kornek V, Reynoso ED, Pinner SE, Bellemare-Pelletier A, Curry MS, Collier AR, Boyd RL, Turley SJ. Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med. 2010 Apr 12;207(4):689-97. Epub 2010 Mar 22. PubMed PMID: 20308362; PubMed Central PMCID: PMC2856033.


Levy C, Khaled M, Robinson KC, Veguilla RA, Chen PH, Yokoyama S, Makino E, Lu J, Larue L, Beermann F, Chin L, Bosenberg M, Song JS, Fisher DE. Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell. 2010 Jun 11;141(6):994-1005. doi: 10.1016/j.cell.2010.05.004. PMID: 20550935 PMCID: PMC2897150 read article


Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, Weiner HL, Green DR, Kuchroo VK. T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8706-11. Epub 2010 Apr 5. PMID: 20368430 PMCID: PMC2889349


Rogers TF, Lim SY, Sundsvold TJ, Chan T, Hsu A, Letvin NL. Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death. Virol J. 2010 Apr 26;7:79. PMID: 20416115 PMCID: PMC2874537 read article


Lim SY, Rogers T, Chan T, Whitney JB, Kim J, Sodroski J, Letvin NL. TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys. PLoS Pathog. 2010 Jan 22;6(1):e1000738. PMID: 20107597 PMCID: PMC2809762 read article


Mayadas TN, Rosetti F, Ernandez T, Sethi S. Neutrophils: game changers in glomerulonephritis? Trends Mol Med. 2010 Aug;16(8):368-78. Epub 2010 Jul 29. Review. PMID: 20667782 PMCID: PMC2925238. read article


Cao S, Ross L, Tamayo G, Clardy J. Asterogynins: secondary metabolites from a Costa Rican endophytic fungus. Org Lett. 2010 Oct 15;12(20):4661-3. doi: 10.1021/ol101972g. PMID: 20839869 PMCID: PMC2951720 read article


Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SM. EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. PLoS Pathog. 2010 Jun 24;6(6):e1000957. doi: 10.1371/journal.ppat.1000957. PMID: 20585630 PMCID: PMC2891827 read article


Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos-Peyton CA, Glimcher LH, Kuchroo VK. (2010). T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol. 40:859-866. PMC2837127.


Sadacca LA, Lamia KA, deLemos AS, Blum B, Weitz CJ. An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice. Diabetologia. 2011 Jan;54(1):120-4. Epub 2010 Oct 3. PubMed PMID: 20890745; PubMed Central PMCID: PMC2995870.


Francisco LM, Sage PT, Sharpe AH. The PD-1 pathway in tolerance and autoimmunity. Immunol Rev. 2010 Jul;236:219-42. PMCID: PMC2919275.


Koduru, S., L. Kumar, M. J. Massaad, N. Ramesh, S. Le Bras, E. Ozcan, M. K. Oyoshi, M. Kaku, Y. Fujiwara, L. Kremer, S. King, R. Fuhlbrigge, S. Rodig, P. Sage, C. Carman, P. Alcaide, F. W. Luscinskas, and R. S. Geha. 2010. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci U S A 107:16252-16256.


Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29;143(3):442-55. PubMed PMID: 21029865; PubMed Central PMCID: PMC2967209.


Singh KK, Ge X, Mao Y, Drane L, Meletis K, Samuels BA, Tsai LH. Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron. 2010 Jul 15;67(1):33-48. PubMed PMID: 20624590; PubMed Central PMCID: PMC2938013.


Schlabach MR, Hu JK, Li M, Elledge SJ. Synthetic design of strong promoters. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2538-43. Epub 2010 Jan 21. PubMed PMID: 20133776; PubMed Central PMCID: PMC2823900.


Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of flavivirus entry derived from the E protein stem. J Virol. 2010 Dec;84(24):12549-54. Epub 2010 Sep 29. PMID: 20881042 PMCID: PMC3004314 read article


Schmidt AG, Yang PL, Harrison SC. Peptide inhibitors of dengue-virus entry target a late-stage fusion intermediate. PLoS Pathog. 2010 Apr 8;6(4):e1000851. PMID: 20386713 PMCID: PMC2851732 read article


Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, Toschi L, Rogers A, Mok T, Sequist L, Lindeman NI, Murphy C, Akhavanfard S, Yeap BY, Xiao Y, Capelletti M, Iafrate AJ, Lee C, Christensen JG, Engelman JA, Jänne PA. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell. 2010 Jan 19;17(1):77-88. doi: 10.1016/j.ccr.2009.11.022. PMID: 20129249 PMCID: PMC2980857 read article


Turke AB, Engelman JA. PIKing the right patient. Clin Cancer Res. 2010 Jul 15;16(14):3523-5. doi: 10.1158/1078-0432.CCR-10-1201. Epub 2010 Jun 10. PMID: 20538763


Schulman S, Wang B, Li W, Rapoport TA. Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15027-32. doi: 10.1073/pnas.1009972107. Epub 2010 Aug 9. PMID: 20696932 PMCID: PMC2930587 read article


Li W, Schulman S, Dutton RJ, Boyd D, Beckwith J, Rapoport TA. Structure of a bacterial homologue of vitamin K epoxide reductase. Nature. 2010 Jan 28;463(7280):507-12. doi: 10.1038/nature08720. PMID: 20110994 PMCID: PMC2919313 read article


Li S, Shankar GM, Selkoe DJ. How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity? Front Cell Neurosci. 2010 Mar 19;4:5. PubMed PMID: 20428510; PubMed Central PMCID: PMC2859875.


Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM, Selkoe DJ, Ince PG, Walsh DM; Medical Research Council Cognitive Function and Ageing Study. The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. Brain. 2010 May;133(Pt 5):1328-41. Epub 2010 Apr 19. PubMed PMID: 20403962; PubMed Central PMCID: PMC2859152.


Shen J, Gilmore EC, Marshall CA, Haddadin M, Reynolds JJ, Eyaid W, Bodell A, Barry B, Gleason D, Allen K, Ganesh VS, Chang BS, Grix A, Hill RS, Topcu M, Caldecott KW, Barkovich AJ, Walsh CA. Mutations in PNKP cause microcephaly, seizures and defects in DNA repair. Nat Genet. 2010 Mar;42(3):245-9. Epub 2010 Jan 31. PubMed PMID: 20118933; PubMed Central PMCID: PMC2835984.


Sircar P, Furr KL, Dorosh LA, Letvin NL. Clonal repertoires of virus-specific CD8+ T lymphocytes are shared in mucosal and systemic compartments during chronic simian immunodeficiency virus infection in rhesus monkeys. J Immunol. 2010 Aug 15;185(4):2191-9. Epub 2010 Jul 12. PMID: 20624939.


Soghoian DZ, Streeck H. Cytolytic CD4(+) T cells in viral immunity. Expert Rev Vaccines. 2010 Dec;9(12):1453-63. doi: 10.1586/erv.10.132. PMID: 21105780 PMCID: PMC3033049 read article


Millet YA, Danna CH, Clay NK, Songnuan W, Simon MD, Werck-Reichhart D, Ausubel FM. Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns. Plant Cell. 2010 Mar;22(3):973-90. Epub 2010 Mar 26. PubMed PMID: 20348432; PubMed Central PMCID: PMC2861455.


Smith AC, Raimondi AR, Salthouse CD, Ignatius MS, Blackburn JS, Mizgirev IV, Storer NY, de Jong JL, Chen AT, Zhou Y, Revskoy S, Zon LI, Langenau DM. High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood. 2010 Apr 22;115(16):3296-303. doi: 10.1182/blood-2009-10-246488. Epub 2010 Jan 7. PMID: 20056790 PMCID: PMC2858492 read article


Younan G, Suber F, Xing W, Shi T, Kunori Y, Abrink M, Pejler G, Schlenner SM, Rodewald HR, Moore FD Jr, Stevens RL, Adachi R, Austen KF, Gurish MF. The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.J Immunol. 2010 Dec 15;185(12):7681-90. doi: 10.4049/jimmunol.1002803. Epub 2010 Nov 12. PMID: 21076070 PMCID: PMC3058366.  read article


Shao RX, Zhang L, Peng LF, Sun E, Chung WJ, Jang JY, Tsai WL, Hyppolite G, Chung RT. Suppressor of cytokine signaling 3 suppresses Hepatitis C Virus replication in an mTOR-dependent manner. J Virol. 2010 Jun;84(12):6060-9. doi: 10.1128/JVI.02484-09. Epub 2010 Apr 7. PMID: 20375166 PMCID: PMC2876663 read article


Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A. The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. PLoS One (2010) 5: 8888. PMID: 20126651. PMCID: PMC2811190.


Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. 2010 Dec 9;468(7325):839-43. PMID: 21057493. PMCID: PMC3003755.


Kulczyk AW, Tanner NA, Loparo JJ, Richardson CC, van Oijen AM. Direct observation of enzymes replicating DNA using a single-molecule DNA stretching assay. J Vis Exp. 2010 Mar 23;(37). pii: 1689. doi: 10.3791/1689. PMID: 20332766 PMCID: PMC2913797 read article


Tanner NA, van Oijen AM. Visualizing DNA replication at the single-molecule level. Methods Enzymol. 2010;475:259-78. doi: 10.1016/S0076-6879(10)75011-4. PMID: 20627161


Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murphy MM, Tepsuporn S, Gatti RA, Look AT, Alt FW. ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification. J Exp Med. 2010 Jul 5;207(7):1369-80. Epub 2010 Jun 21. PubMed PMID: 20566716. PMCID: PMC2901073.


Thomas M, Lieberman J, Lal A. Desperately seeking microRNA targets. Nat Struct Mol Biol. 2010 Oct;17(10):1169-74. doi: 10.1038/nsmb.1921. PMID: 20924405


Cronican JJ, Thompson DB, Beier KT, McNaughton BR, Cepko CL, Liu DR. Potent delivery of functional proteins into Mammalian cells in vitro and in vivo using a supercharged protein. ACS Chem Biol. 2010 Aug 20;5(8):747-52. doi: 10.1021/cb1001153. PMID: 20545362 PMCID: PMC2924640 read article


Demer JL, Clark RA, Tischfield MA, Engle EC. Evidence of an asymmetrical endophenotype in congenital fibrosis of extraocular muscles type 3 resulting from TUBB3 mutations. Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4600-11. Epub 2010 Apr 14. PubMed PMID: 20393110; PubMed Central PMCID: PMC2941178.


Tischfield MA, Baris HN, Wu C, Rudolph G, Van Maldergem L, He W, Chan WM, Andrews C, Demer JL, Robertson RL, Mackey DA, Ruddle JB, Bird TD, Gottlob I, Pieh C, Traboulsi EI, Pomeroy SL, Hunter DG, Soul JS, Newlin A, Sabol LJ, Doherty EJ, de Uzcátegui CE, de Uzcátegui N, Collins ML, Sener EC, Wabbels B, Hellebrand H, Meitinger T, de Berardinis T, Magli A, Schiavi C, Pastore Trossello M, Koc F, Wong AM, Levin AV, Geraghty MT, Descartes M, Flaherty M, Jamieson RV, Møller HU, Meuthen I, Callen DF, Kerwin J, Lindsay S, Meindl A, Gupta ML Jr, Pellman D, Engle EC. Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance. Cell. 2010 Jan 8;140(1):74 87. PubMed PMID: 20074521. PMCID: PMC3164117


Demer JL, Clark RA, Tischfield MA, Engle EC. Evidence of an asymmetrical endophenotype in congenital fibrosis of extraocular muscles type 3 resulting from TUBB3 mutations. Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4600-11. Epub 2010 Apr 14. PubMed PMID: 20393110; PubMed Central PMCID: PMC2941178.


Tukachinsky H, Lopez LV, Salic A. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. J Cell Biol. 2010 Oct 18;191(2):415-28. doi: 10.1083/jcb.201004108. PMID: 20956384 PMCID: PMC2958481 read article


Vijayan S, Hale GJ, Moore CI, Brown EN, Wilson M. Activity in the barrel cortex during active behavior and sleep. J Neurophysiol. 2010 Apr;103(4):2074-84. Epub 2010 Feb 17. PubMed PMID: 20164403; PubMed Central PMCID: PMC2853270.


Vo TT, Letai A. BH3-only proteins and their effects on cancer. Adv Exp Med Biol. 2010;687:49-63. PMID: 20919637 PMCID: PMC3733261 read article


Black JC, Allen A, Van Rechem C, Forbes E, Longworth M, Tschöp K, Rinehart C, Quiton J, Walsh R, Smallwood A, Dyson NJ, Whetstine JR. Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression. Mol Cell. 2010 Dec 10;40(5):736-48. doi: 10.1016/j.molcel.2010.11.008. PMID: 21145482


Walsh RM, Hochedlinger K. Modeling Rett syndrome with stem cells. Cell. 2010 Nov 12;143(4):499-500. doi: 10.1016/j.cell.2010.10.037. PMID: 21074040 PMCID: PMC3538362  read article


Gill JC, Wang O, Kakar S, Martinelli E, Carroll RS, Kaiser UB. Reproductive hormone-dependent and -independent contributions to developmental changes in kisspeptin in GnRH-deficient hypogonadal mice. PLoS One. 2010 Jul 30;5(7):e11911. PubMed PMID: 20689830; PubMed Central PMCID: PMC2912854.


Birk E, Har-Zahav A, Manzini CM, Pasmanik-Chor M, Kornreich L, Walsh CA, Noben-Trauth K, Albin A, Simon AJ, Colleaux L, Morad Y, Rainshtein L, Tischfield DJ, Wang P, Magal N, Maya I, Shoshani N, Rechavi G, Gothelf D, Maydan G, Shohat M, Basel-Vanagaite L. SOBP is mutated in syndromic and nonsyndromic intellectual disability and is highly expressed in the brain limbic system. Am J Hum Genet. 2010 Nov 12;87(5):694-700. Epub 2010 Oct 28. PMID: 21035105 PMCID: PMC2978971  read article


de Jong JL, Davidson AJ, Wang Y, Palis J, Opara P, Pugach E, Daley GQ, Zon LI. Interaction of retinoic acid and scl controls primitive blood development. Blood. 2010 Jul 15;116(2):201-9. doi: 10.1182/blood-2009-10-249557. Epub 2010 Apr 21. PMID: 20410509 PMCID: PMC2910607 read article


Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science. 2010 Mar 26;327(5973):1650-3. doi: 10.1126/science.1186624. PMID: 20339075 PMCID: PMC3084586 read article


Sakuma M, Morooka T, Wang Y, Shi C, Croce K, Gao H, Strainic M, Medof ME, Simon DI. The Intrinsic Complement Regulator Decay-Accelerating Factor Modulates the Biological Response to Vascular Injury. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1196-202. doi: 10.1161/ATVBAHA.110.205559. Epub 2010 Mar 18. PMID: 20299685 PMCID: PMC2903214 read article


Nozari A, Dilekoz E, Sukhotinsky I, Stein T, Eikermann-Haerter K, Liu C, Wang Y, Frosch MP, Waeber C, Ayata C, Moskowitz MA. Microemboli may link spreading depression, migraine aura, and patent foramen ovale. Ann Neurol. 2010 Feb;67(2):221-9. doi: 10.1002/ana.21871. PMID: 20225282 PMCID: PMC2921919 read article


Wang H, Wu X, Wang Y, Oldenborg PA, Yang YG. CD47 is required for suppression of allograft rejection by donor-specific transfusion. J Immunol. 2010 Apr 1;184(7):3401-7. doi: 10.4049/jimmunol.0901550. Epub 2010 Mar 5. PMID: 20208011 PMCID: PMC3670954 read article


Tung N, Wang Y, Collins LC, Kaplan J, Li H, Gelman R, Comander AH, Gallagher B, Fetten K, Krag K, Stoeckert KA, Legare RD, Sgroi D, Ryan PD, Garber JE, Schnitt SJ. Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic features. Breast Cancer Res. 2010;12(1):R12. doi: 10.1186/bcr2478. Epub 2010 Feb 11. PMID: 20149218 PMCID: PMC2880433


Xu X, Yang Z, Liu Q, Wang Y. In vivo fluorescence imaging of muscle cell regeneration by transplanted EGFP-labeled myoblasts. Mol Ther. 2010 Apr;18(4):835-42. Epub 2010 Feb 2. PubMed PMID: 20125125. read article


Simunovic F, Yi M, Wang Y, Stephens R, Sonntag KC. Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease. PLoS One. 2010 Jan 25;5(1):e8856. doi: 10.1371/journal.pone.0008856. PMID: 20111594 PMCID: PMC2810324 read article


Nishio J, Feuerer M, Wong J, Mathis D, Benoist C. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J Exp Med. 2010 Aug 30;207(9):1879-89. Epub 2010 Aug 2. PMID: 20679403. PMCID: PMC2931163.


Musunuru K, Strong A, Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, Racie T, Ejebe KG, Orho-Melander M, Melander O, Koteliansky V, Fitzgerald K, Krauss RM, Cowan CA, Kathiresan S, Rader DJ. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature. 2010 Aug 5;466(7307):714-9. PMID: 20686566. PMCID: PMC3062476.


Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SM. EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. PLoS Pathog. 2010 Jun 24;6(6):e1000957. PubMed PMID: 20585630; PubMed Central PMCID: PMC2891827.


Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, Kreidberg JA. Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. Development. 2010 Apr;137(7):1189-203. doi: 10.1242/dev.045732. PMID: 20215353 PMCID: PMC2835332 read article


Alterovitz G, Xiang M, Hill DP, Lomax J, Liu J, Cherkassky M, Dreyfuss J, Mungall C, Harris MA, Dolan ME, Blake JA, Ramoni MF. Ontology engineering. Nat Biotechnol. 2010 Feb;28(2):128-30. doi: 10.1038/nbt0210-128. PMID: 20139945


Xu C, Lo A, Yammanuru A, Tallarico AS, Brady K, Murakami A, Barteneva N, Zhu Q, Marasco WA. Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology. PLoS One. 2010 Mar 10;5(3):e9625. PubMed PMID: 20224781; PubMed Central PMCID: PMC2835754.


Vandorpe DH, Xu C, Shmukler BE, Otterbein LE, Trudel M, Sachs F, Gottlieb PA, Brugnara C, Alper SL. Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes. PLoS One. 2010 Jan 15;5(1):e8732. PubMed PMID: 20090940; PubMed Central PMCID: PMC2806905.


Huang M, Kim JM, Shiotani B, Yang K, Zou L, D'Andrea AD. The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Mol Cell. 2010 Jul 30;39(2):259-68. PubMed PMID: 20670894; PubMed Central PMCID: PMC2928996.


Yang Y, Bonni A. Releasing the brake on presynaptic development: Cdc20-APC triggers neuroD2 degradation to drive presynaptic differentiation. Cell Cycle. 2010 Jun 6;9(12). [Epub ahead of print] PubMed PMID: 20699636. PMCID: PMC3096709


de la Torre-Ubieta L, Gaudillière B, Yang Y, Ikeuchi Y, Yamada T, DiBacco S, Stegmüller J, Schüller U, Salih DA, Rowitch D, Brunet A, Bonni A. A FOXO-Pak1 transcriptional pathway controls neuronal polarity. Genes Dev. 2010 Apr 15;24(8):799-813. PubMed PMID: 20395366; PubMed Central PMCID: PMC2854394.


Yang Y, Kim AH, Bonni A. The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity. Curr Opin Neurobiol. 2010 Feb;20(1):92-9. Epub 2010 Jan 7. Review. PubMed PMID: 20060286.


Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604. Epub 2010 Dec 15. PMID: 21160472 PMCID: PMC3058373 read article


Zeng X, Sigoillot F, Gaur S, Choi S, Pfaff KL, Oh DC, Hathaway N, Dimova N, Cuny GD, King RW. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell. 2010 Oct 19;18(4):382-95. PubMed PMID: 20951947; PubMed Central PMCID: PMC2957475.


Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW. Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions. Proceedings of the National Academy of Sciences USA. 2010 Feb 16;107(7):3040-5. PMCID: PMC2840363.


Lipinski MM, Hoffman G, Ng A, Zhou W, Py BF, Hsu E, Liu X, Eisenberg J, Liu J, Blenis J, Xavier RJ, Yuan J. A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions. Dev Cell. 2010 Jun 15;18(6):1041-52. doi: 10.1016/j.devcel.2010.05.005. PMID: 20627085 PMCID: PMC2935848 read article


top

2009


Azim E, Shnider SJ, Cederquist GY, Sohur US, Macklis JD. Lmo4 and Clim1 progressively delineate cortical projection neuron subtypes during development. Cereb Cortex. 2009 Jul;19 Suppl 1:i62-9. Epub 2009 Apr 14. PubMed PMID: 19366868; PubMed Central PMCID: PMC2693532.


Azim E, Jabaudon D, Fame RM, Macklis JD. SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development. Nat Neurosci. 2009 Oct;12(10):1238-47. Epub 2009 Aug 5. PubMed PMID: 19657336; PubMed Central PMCID: PMC2903203.


Agapakis CM, Silver PA. Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks. Mol Biosyst. 2009 Jul;5(7):704-13. doi: 10.1039/b901484e. Epub 2009 May 14. PMID: 19562109


Zhang L, Agosto MA, Ivanovic T, King DS, Nibert ML, Harrison SC. Requirements for the formation of membrane pores by the reovirus myristoylated micro1N peptide. J Virol. 2009 Jul;83(14):7004-14. doi: 10.1128/JVI.00377-09. Epub 2009 May 13. PMID: 19439475 PMCID: PMC2704788 read article


Soucy ER, Albeanu DF, Fantana AL, Murthy VN, Meister M. Precision and diversity in an odor map on the olfactory bulb. Nat Neurosci. 2009 Feb;12(2):210-20. Epub 2009 Jan 18. PubMed PMID: 19151709.


Aoki ST, Settembre EC, Trask SD, Greenberg HB, Harrison SC, Dormitzer PR. Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab. Science. 2009 Jun 12;324(5933):1444-7. PMID: 19520960 PMCID: PMC2995306 read article


Chen JZ, Settembre EC, Aoki ST, Zhang X, Bellamy AR, Dormitzer PR, Harrison SC, Grigorieff N. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10644-8. Epub 2009 Jun 1. PMID: 19487668 PMCID: PMC2689313 read article


Ardayfio PA, Leung A, Park J, Hwang DY, Moran-Gates T, Choi YK, Carlezon WA Jr, Tarazi FI, Kim KS. Pitx3-deficient aphakia mice display unique behavioral responses to psychostimulant and antipsychotic drugs. Neuroscience. 2010 Mar 17;166(2):391-6. Epub 2009 Dec 22. PubMed PMID: 20026251; PubMed Central PMCID: PMC2842920.


Armour SM, Baur JA, Hsieh SN, Land-Bracha A, Thomas SM, Sinclair DA. Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy. Aging (Albany NY). 2009 Jun 3;1(6):515-28. PMID: 20157535 PMCID: PMC2806030 read article


Berg J, Hung YP, Yellen G. A genetically encoded fluorescent reporter of ATP:ADP ratio. Nat Methods. 2009 Feb;6(2):161-6. Epub 2009 Jan 4. PubMed PMID: 19122669; PubMed Central PMCID: PMC2633436.


Kim AH, Puram SV, Bilimoria PM, Ikeuchi Y, Keough S, Wong M, Rowitch D, Bonni A. A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell. 2009 Jan 23;136(2):322-36. PubMed PMID: 19167333; PubMed Central PMCID: PMC2707082.


Mohideen F, Capili AD, Bilimoria PM, Yamada T, Bonni A, Lima CD. A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9. Nat Struct Mol Biol. 2009 Sep;16(9):945-52. Epub 2009 Aug 16. PubMed PMID: 19684601; PubMed Central PMCID: PMC2771680.


Yang Y, Kim AH, Yamada T, Wu B, Bilimoria PM, Ikeuchi Y, de la Iglesia N, Shen J, Bonni A. A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science. 2009 Oct 23;326(5952):575-8. PubMed PMID: 19900895; PubMed Central PMCID: PMC2846784.


Schrum JP, Ricardo A, Krishnamurthy M, Blain JC, Szostak JW. Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers. J Am Chem Soc. 2009 Oct 14;131(40):14560-70. PubMed PMID: 19757789; PubMed Central PMCID: PMC2759813.


Bloodgood BL, Giessel AJ, Sabatini BL. Biphasic synaptic Ca influx arising from compartmentalized electrical signals in dendritic spines. PLoS Biol. 2009 Sep;7(9):e1000190. Epub 2009 Sep 15. PubMed PMID: 19753104; PubMed Central PMCID: PMC2734993.


Akselrod-Ballin A, Bock D, Reid RC, Warfield SK. Accelerating feature based registration using the Johnson-Lindenstrauss Lemma. Med Image Comput Comput Assist Interv. 2009;12(Pt 1):632-9. PubMed PMID: 20426041.


Boutwell CL, Rowley CF, Essex M. Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein. J Virol. 2009 Mar;83(6):2460-8. doi: 10.1128/JVI.01970-08. Epub 2008 Dec 24. PMID: 19109381 PMCID: PMC2648284 read article


Bowman JJ, Schaffer PA. Origin of expression of the herpes simplex virus type 1 protein U(S)1.5. J Virol. 2009 Sep;83(18):9183-94. Epub 2009 Jul 1. PMID: 19570862 PMCID: PMC2738232 read article


Bowman JJ, Orlando JS, Davido DJ, Kushnir AS, Schaffer PA. Transient expression of herpes simplex virus type 1 ICP22 represses viral promoter activity and complements the replication of an ICP22 null virus. J Virol. 2009 Sep;83(17):8733-43. Epub 2009 Jun 17. PMID: 19535441 PMCID: PMC2738139 read article


Py BF, Boyce M, Yuan J. A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses. Autophagy. 2009 Apr;5(3):393-6. Epub 2009 Apr 6. PMID: 19221463 PMCID: PMC2756538 read article


Boyle PM, Silver PA. Harnessing nature's toolbox: regulatory elements for synthetic biology. J R Soc Interface. 2009 Aug 6;6 Suppl 4:S535-46. doi: 10.1098/rsif.2008.0521.focus. Epub 2009 Mar 4. PMID: 19324675 PMCID: PMC2843961 read article


Kennedy CJ, Boyle PM, Waks Z, Silver PA. Systems-level engineering of nonfermentative metabolism in yeast. Genetics. 2009 Sep;183(1):385-97. doi: 10.1534/genetics.109.105254. Epub 2009 Jun 29. PMID: 19564482 PMCID: PMC2746161


Brown KM, Depristo MA, Weinreich DM, Hartl DL. Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways. Mol Biol Evol. 2009 Nov;26(11):2455-62. Epub 2009 Jul 14. PubMed PMID: 19602543.


Lozovsky ER, Chookajorn T, Brown KM, Imwong M, Shaw PJ, Kamchonwongpaisan S, Neafsey DE, Weinreich DM, Hartl DL. Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12025-30. Epub 2009 Jul 8. PubMed PMID: 19587242; PubMed Central PMCID: PMC2715478.


Francisco LM, Salinas VH, Brown KE, Vanguri VK, Freeman GJ, Kuchroo VK, Sharpe AH. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med. 2009 Dec 21;206(13):3015-29. Epub 2009 Dec 14. PubMed PMID: 20008522; PubMed Central PMCID: PMC2806460.


Bruckner RJ, Mansy SS, Ricardo A, Mahadevan L, Szostak JW. Flip-flop-induced relaxation of bending energy: implications for membrane remodeling. Biophys J. 2009 Dec 16;97(12):3113-22. PubMed PMID: 20006948; PubMed Central PMCID: PMC2793357.


Budin I, Bruckner RJ, Szostak JW. Formation of protocell-like vesicles in a thermal diffusion column. J Am Chem Soc. 2009 Jul 22;131(28):9628-9. PubMed PMID: 19601679; PubMed Central PMCID: PMC2710859.


Blachon S, Cai X, Roberts KA, Yang K, Polyanovsky A, Church A, Avidor-Reiss T. A proximal centriole-like structure is present in Drosophila spermatids and can serve as a model to study centriole duplication. Genetics. 2009 May;182(1):133-44. doi: 10.1534/genetics.109.101709. Epub 2009 Mar 16. PMID: 19293139 PMCID: PMC2674812 read article


MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, Fiorentino M, Rubin MA, Polyak K, Chan J, Wang Y, Fletcher JA, Santagata S, Corso G, Roviello F, Shivdasani R, Kieran MW, Ligon KL, Stiles CD, Hahn WC, Meyerson ML, Garraway LA. Profiling critical cancer gene mutations in clinical tumor samples. PLoS One. 2009 Nov 18;4(11):e7887. PubMed PMID: 19924296; PubMed Central PMCID: PMC2774511.


Carter BC, Bean BP. Sodium entry during action potentials of mammalianneurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons. Neuron. 2009 Dec 24;64(6):898-909. PubMed PMID: 20064395; PubMed Central PMCID: PMC2810867.


Berriz GF, Beaver JE, Cenik C, Tasan M, Roth FP. Next generation software for functional trend analysis. Bioinformatics. 2009 Nov 15;25(22):3043-4. Epub 2009 Aug 28. PubMed PMID: 19717575; PubMed Central PMCID: PMC2800365.


Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science. 2009 Oct 9;326(5950):257-63. Epub 2009 Sep 3. PMID: 19729616 PMCID: PMC2879337 read article


Chiu IM, Phatnani H, Kuligowski M, Tapia JC, Carrasco MA, Zhang M, Maniatis T, Carroll MC. Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20960-5. Epub 2009 Nov 20. PMID: 19933335. PMCID: PMC2791631.


Qiao L, Choi S, Case A, Gainer TG, Seyb K, Glicksman MA, Lo DC, Stein RL, Cuny GD. Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6122-6. Epub 2009 Sep 9. PubMed PMID: 19783434; PubMed Central PMCID: PMC2785710.


Hwang DY, Hong S, Jeong JW, Choi S, Kim H, Kim J, Kim KS. Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons. J Neurochem. 2009 Dec;111(5):1202-12. Epub 2009 Sep 24. PubMed PMID: 19780901.


Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA. Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17. Epub 2009 Mar 15. PubMed PMID: 19287388; PubMed Central PMCID: PMC2676236.


Schwartz D, Chou MF, Church GM. Predicting protein post-translational modifications using meta-analysis of proteome scale data sets. Mol Cell Proteomics. 2009 Feb;8(2):365-79. Epub 2008 Oct 28. PubMed PMID: 18974045; PubMed Central PMCID: PMC2634583.


Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, García-Añoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO. Mutant sodium channel for tumor therapy. Mol Ther. 2009 May;17(5):810-9. Epub 2009 Mar 3. PubMed PMID: 19259066; PubMed Central PMCID: PMC2751883.


Kuo TT, de Muinck EJ, Claypool SM, Yoshida M, Nagaishi T, Aveson VG, Lencer WI, Blumberg RS. N-glycan moieties in FcRn determine steady-state membrane distribution and directional transport of IgG. J Biol Chem. 2009 Mar 27;284(13):8292-300. PMCID: PMC2659187.


Cohen NR, Garg S, Brenner MB. Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity. Adv Immunol. 2009;102:1-94. Review. PubMed PMID: 19477319.


Chiba, A; Cohen, N; Brigl, M; Brennan, PJ; Besra, GS & Brenner, MB. Rapid and reliable generation of invariant natural killer T cell lines in vitro. Immunology. 2009. 128(3):324-33. PMCID: PMC2770680.


Cornejo MG, Kharas MG, Werneck MB, Le Bras S, Moore SA, Rodig S, Aster JC, Lee BH, Cantor H, Gilliland DG, Mercher T. Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood, 2009 Mar 19; 113 (12); 2746-54. PMCID: PMC2661862.


Mercher T, Raffel GD, Moore SA, Cornejo MG, Baudry-Bluteau D, Cagnard N, Jesneck JL, Pikman Y, Cullen D, Williams IR, Akashi K, Shigematsu H, Bourquin JP, Giovannini M, Vainchenker W, Levine RL, Lee BH, Bernard OA, Gilliland DG.The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model. J Clin Invest. 2009 Apr; 119 (4):852-64. PMCID: PMC2662544.


Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 2009 Jun 5; 4(6):559-67. PMCID: PMC3065323.


Moellering RE, Cornejo MG, Del Bianco C, Hancock M, Aster JC, Blacklow SC, Gilliland DG, Verdine GL, Bradner JE. Direct Inhibition of the Notch Transcription Factor Complex. Nature. 2009 Nov 12; 462(7270): 182-8. PMCID: PMC2951323.


Cornejo MG, Boggon TJ, Mercher T. JAK3: a two-faced player in hematological disorders. (Int J Biochem Cell Biol. 2009 Dec; 41(12): 2376-9) PMCID: PMC2853879.


Costantino CM, Ploegh HL, Hafler DA. Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells. J Immunol. 2009 Jul 15;183(2):945-52. Epub 2009 Jun 24. PubMed PMID: 19553543; PubMed Central PMCID: PMC2752291.


Beriou G, Costantino CM, Ashley CW, Yang L, Kuchroo VK, Baecher-Allan C, Hafler DA. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood. 2009 Apr 30;113(18):4240-9. Epub 2009 Jan 26. PubMed PMID: 19171879; PubMed Central PMCID: PMC2676084.


Pazyra-Murphy MF, Hans A, Courchesne SL, Karch C, Cosker KE, Heerssen HM, Watson FL, Kim T, Greenberg ME, Segal RA. A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl w. J Neurosci. 2009 May 20;29(20):6700-9. PubMed PMID: 19458239; PubMed Central PMCID: PMC2709981.


Ramduth D, Day CL, Thobakgale CF, Mkhwanazi NP, de Pierres C, Reddy S, van der Stok M, Mncube Z, Nair K, Moodley ES, Kaufmann DE, Streeck H, Coovadia HM, Kiepiela P, Goulder PJ, Walker BD. Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection. PLoS One. 2009;4(4):e5013. doi: 10.1371/journal.pone.0005013. Epub 2009 Apr 7. PMID: 19352428 PMCID: PMC2661367  read article


Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science. 2009 Oct 9;326(5950):257-63. doi: 10.1126/science.1179050. Epub 2009 Sep 3. PMID: 19729616 PMCID: PMC2879337 read article


Mahoney SJ, Dempsey JM, Blenis J. Cell signaling in protein synthesis ribosome biogenesis and translation initiation and elongation. Prog Mol Biol Transl Sci. 2009;90:53-107. doi: 10.1016/S1877-1173(09)90002-3. Epub 2009 Oct 27. PMID: 20374739


Djuretic IM, Cruz-Guilloty F, Rao A. Regulation of gene expression in peripheral T cells by Runx transcription factors. Adv Immunol. 2009;104:1-23. Epub 2009 Dec 1. Review. PubMed PMID: 20457114.


Cruz-Guilloty F, Pipkin ME, Djuretic IM, Levanon D, Lotem J, Lichtenheld MG, Groner Y, Rao A. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J Exp Med. 2009 Jan 16;206(1):51-9. Epub 2009 Jan 12. PubMed PMID: 19139168; PubMed Central PMCID: PMC2626671.


Dougan M, Dranoff G. The immune response to tumors. Curr Protoc Immunol. 2009 Apr;Chapter 20:Unit 20.11. PMID: 19347848


Dougan M, Dranoff G.Immune Therapy for Cancer. Annu Rev Immunol. 2009;27:83-117. Review. PMID: 19007331


Hu CC, Dougan SK, McGehee AM, Love JC, Ploegh HL. XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells. EMBO J. 2009 Jun 3;28(11):1624-36. Epub 2009 Apr 30. PubMed PMID: 19407814; PubMed Central PMCID: PMC2684024.


Dovey MC, Zon LI. Defining cancer stem cells by xenotransplantation in zebrafish. Methods Mol Biol. 2009;568:1-5. doi: 10.1007/978-1-59745-280-9_1. PMID: 19582417


Dovey M, Patton EE, Bowman T, North T, Goessling W, Zhou Y, Zon LI. Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Mol Cell Biol. 2009 Jul;29(13):3746-53. doi: 10.1128/MCB.01684-08. Epub 2009 Apr 20. PMID: 19380487PMCID: PMC2698760 read article


Dovey M, White RM, Zon LI. Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. Zebrafish. 2009 Dec;6(4):397-404. doi: 10.1089/zeb.2009.0606. PMID: 19954345 PMCID: PMC2943216 read article


Dutton RJ, Wayman A, Wei JR, Rubin EJ, Beckwith J, Boyd D. Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin. Proc Natl Acad Sci USA. 2010 Jan 5;107(1):297-301. Epub 2009 Dec 15. PubMed PMID: 20018758; PubMed Central PMCID: PMC2806739.


Ebina W, Rowat AC, Weitz DA. Electrodes on a budget: Micropatterned electrode fabrication by wet chemical deposition. Electrodes on a budget: Micropatterned electrode fabrication by wet chemical deposition. Biomicrofluidics. 2009 Sep 8;3(3):34104. PMID: 20216960 PMCID: PMC2835278 read article


Soucy ER, Albeanu DF, Fantana AL, Murthy VN, Meister M. Precision and diversity in an odor map on the olfactory bulb. Nat Neurosci. 2009 Feb;12(2):210-20. Epub 2009 Jan 18. PubMed PMID: 19151709.


Fiore R, Khudayberdiev S, Christensen M, Siegel G, Flavell SW, Kim TK, Greenberg ME, Schratt G. Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 2009 Mar 18;28(6):697-710. Epub 2009 Feb 5. PubMed PMID: 19197241; PubMed Central PMCID: PMC2647767.


Liu Z, Meray RK, Grammatopoulos TN, Fredenburg RA, Cookson MR, Liu Y, Logan T, Lansbury PT Jr. Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4635-40. doi: 10.1073/pnas.0806474106. Epub 2009 Mar 4. PMID: 19261853 PMCID: PMC2651203 read article


Egyud MR, Gajdos ZK, Butler JL, Tischfield S, Le Marchand L, Kolonel LN, Haiman CA, Henderson BE, Hirschhorn JN. Use of weighted reference panels based on empirical estimates of ancestry for capturing untyped variation. Hum Genet. 2009 Apr;125(3):295-303. Epub 2009 Jan 28. PubMed PMID: 19184111.


Gajdos ZK, Hirschhorn JN, Palmert MR. What controls the timing of puberty? An update on progress from genetic investigation. Curr Opin Endocrinol Diabetes Obes. 2009 Feb;16(1):16-24. Review. PubMed PMID: 19104234.


Ganis JJ, Hsia N, Trompouki E, de Jong JL, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, Zon LI. Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol. 2012 Jun 15;366(2):185-94. Epub 2012 Apr 19. PubMed PMID: 22537494; PubMed Central PMCID: PMC3378398.  read article


Cohen NR, Garg S, Brenner MB. Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity. Adv Immunol. 2009;102:1-94. Review. PMID: 19477319


Veerapen N, Brigl M, Garg S, Cerundolo V, Cox LR, Brenner MB, Besra GS. Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4288-91. Epub 2009 May 27. PMID: 19502056. PMCID: PMC2722241


Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T, Singh KK, Biechele T, Petryshen TL, Moon RT, Haggarty SJ, Tsai LH. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell. 2009 Mar 20;136(6):1017-31. PubMed PMID: 19303846; PubMed Central PMCID: PMC2704382.


Gelfand MV, Hong S, Gu C. Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning. Trends Cell Biol. 2009 Mar;19(3):99-110. Epub 2009 Feb 4. Review. PubMed PMID: 19200729.


Bloodgood BL, Giessel AJ, Sabatini BL. Biphasic synaptic Ca influx arisingfrom compartmentalized electrical signals in dendritic spines. PLoS Biol. 2009 Sep;7(9):e1000190. Epub 2009 Sep 15. PubMed PMID: 19753104; PubMed Central PMCID: PMC2734993.


Goldman JA, Garlick JD, Kingston RE. Chromatin remodeling by imitation switch (ISWI) class ATP-dependent remodelers is stimulated by histone variant H2A.Z. J Biol Chem. 2010 Feb 12;285(7):4645-51. Epub 2009 Nov 25. PubMed PMID: 19940112; PubMed Central PMCID: PMC2836070.


Tolstorukov MY, Kharchenko PV, Goldman JA, Kingston RE, Park PJ. Comparative analysis of H2A.Z nucleosome organization in the human and yeast genomes. Genome Res. 2009 Jun;19(6):967-77. Epub 2009 Feb 26. PubMed PMID: 19246569; PubMed Central PMCID: PMC2694475.


Gouwens NW, Wilson RI. Signal propagation in Drosophila central neurons. J Neurosci. 2009 May 13;29(19):6239-49. PubMed PMID: 19439602; PubMed Central PMCID: PMC2709801.


Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 2009 Sep 3;461(7260):109-13. Epub 2009 Aug 19. PubMed PMID: 19693011; PubMed Central PMCID: PMC2931797.


Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH. TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J. 2009 Jul 22;28(14):2028-41. Epub 2009 Jun 18. PMID: 19536134


Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d. J Biol Chem. 2009 Dec 4;284(49):33800-6. Epub 2009 Oct 15. PMID: 19833737 PMCID: PMC2797149 read article


Scholz J, Mannion RJ, Hord DE, Griffin RS, Rawal B, Zheng H, Scoffings D, Phillips A, Guo J, Laing RJ, Abdi S, Decosterd I, Woolf CJ. A novel tool for the assessment of pain: validation in low back pain. PLoS Med. 2009 Apr 7;6(4):e1000047. Epub 2009 Apr 7. PubMed PMID: 19360087; PubMed Central PMCID: PMC2661253.


Hall JA, Bianco AC. Triumphs of the thyroid despite lesser conversion. Endocrinology. 2009 Jun;150(6):2502-4. doi: 10.1210/en.2009-0347. PMID: 19458245


Pazyra-Murphy MF, Hans A, Courchesne SL, Karch C, Cosker KE, Heerssen HM, Watson FL, Kim T, Greenberg ME, Segal RA. A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w. J Neurosci. 2009 May 20;29(20):6700-9. PubMed PMID: 19458239; PubMed Central PMCID: PMC2709981.


Hemming ML, Elias JE, Gygi SP, Selkoe DJ. Identification of beta-secretase (BACE1) substrates using quantitative proteomics. PLoS One. 2009 Dec 29;4(12):e8477. PubMed PMID: 20041192; PubMed Central PMCID: PMC2793532.


Beltman JB, Henrickson SE, von Andrian UH, de Boer RJ, Marée AF. Towards estimating the true duration of dendritic cell interactions with T cells. J Immunol Methods. 2009 Aug 15;347(1-2):54-69. Epub 2009 Jun 9. PMID: 19520083


Herrington TM, Assad JA. Neural activity in the middle temporal area and lateral intraparietal area during endogenously cued shifts of attention. J Neurosci. 2009 Nov 11;29(45):14160-76. PubMed PMID: 19906965; PubMed Central PMCID: PMC2913246.


Herrington TM, Masse NY, Hachmeh KJ, Smith JE, Assad JA, Cook EP. The effect of microsaccades on the correlation between neural activity and behavior in middle temporal, ventral intraparietal, and lateral intraparietal areas. J Neurosci. 2009 May 6;29(18):5793-805. PubMed PMID: 19420247; PubMed Central PMCID: PMC2904875.


Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron. 2009 Jun 25;62(6):788-801. PubMed PMID: 19555648; PubMed Central PMCID: PMC2702854.


Li C, Houser BL, Nicotra ML, Strominger JL. HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human decidual macrophages and natural killer cells. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5767-72. Epub 2009 Mar 20. PMCID: PMC2667005.


Huynh MA, Stegmüller J, Litterman N, Bonni A. Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation. J Neurosci. 2009 Apr 1;29(13):4322-7. doi: 10.1523/JNEUROSCI.5329-08.2009. PMID: 19339626 PMCID: PMC2839872 read article


Ikeuchi Y, Stegmüller J, Netherton S, Huynh MA, Masu M, Frank D, Bonni S, Bonni A. A SnoN-Ccd1 pathway promotes axonal morphogenesis in the mammalian brain. J Neurosci. 2009 Apr 1;29(13):4312-21. doi: 10.1523/JNEUROSCI.0126-09.2009. PMID: 19339625 PMCID: PMC2853192 read article


Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, Egli D, Loh KM, Carter AC, Di Giorgio FP, Koszka K, Huangfu D, Akutsu H, Liu DR, Rubin LL, Eggan K. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell. 2009 Nov 6;5(5):491-503. Epub 2009 Oct 8. PubMed PMID: 19818703.


Jadhav AP, Roesch K, Cepko CL. Development and neurogenic potential of Müller glial cells in the vertebrate retina. Prog Retin Eye Res. 2009 Jul;28(4):249-62. doi: 10.1016/j.preteyeres.2009.05.002. Epub 2009 May 22. PMID: 19465144 PMCID: PMC3233204 read article


Zimmermann K, Hein A, Hager U, Kaczmarek JS, Turnquist BP, Clapham DE, Reeh PW. Phenotyping sensory nerve endings in vitro in the mouse. Nat Protoc. 2009;4(2):174-96. PubMed PMID: 19180088.


Ramsey IS, Ruchti E, Kaczmarek JS, Clapham DE. Hv1 proton channels arerequired for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7642-7. Epub 2009 Apr 16. PubMed PMID: 19372380; PubMed Central PMCID: PMC2669790.


Blair NT, Kaczmarek JS, Clapham DE. Intracellular calcium strongly potentiates agonist-activated TRPC5 channels. J Gen Physiol. 2009 May;133(5):525-46. PubMed PMID: 19398778; PubMed Central PMCID: PMC2712973.


Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 2009 Feb 15;23(4):496-511. doi: 10.1101/gad.1775409. PMID: 19240135 PMCID: PMC2648650 read article


Trask SD, Kim IS, Harrison SC, Dormitzer PR. A rotavirus spike protein conformational intermediate binds lipid bilayers. J Virol. 2010 Feb;84(4):1764-70. Epub 2009 Dec 9. PMID: 20007281 PMCID: PMC2812363 read article


Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. Cancer Cell. 2009 Jul 7;16(1):21-32. doi: 10.1016/j.ccr.2009.04.012. PMID: 19573809 PMCID: PMC2752826 read article


Emery CM, Vijayendran KG, Zipser MC, Sawyer AM, Niu L, Kim JJ, Hatton C, Chopra R, Oberholzer PA, Karpova MB, MacConaill LE, Zhang J, Gray NS, Sellers WR, Dummer R, Garraway LA. MEK1 mutations confer resistance to MEK and B-RAF inhibition. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20411-6. doi: 10.1073/pnas.0905833106. Epub 2009 Nov 13. PMID: 19915144 PMCID: PMC2777185 read article


Carlezon WA Jr, Béguin C, Knoll AT, Cohen BM. Kappa-opioid ligands in the study and treatment of mood disorders. Pharmacol Ther. 2009 Sep;123(3):334-43. Epub 2009 Jun 2. Review. PubMed PMID: 19497337; PubMed Central PMCID: PMC2740476.


Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science. 2009 Jun 5;324(5932):1334-8. PMCID: PMC2803727.


Rahmeh AA, Li J, Kranzusch PJ, Whelan SP. Ribose 2'-O methylation of the vesicular stomatitis virus mRNA cap precedes and facilitates subsequent guanine-N-7 methylation by the large polymerase protein. J Virol. 2009 Nov;83(21):11043-50. Epub 2009 Aug 26. PMID: 19710136 PMCID: PMC2772757.  read article


Kreslavsky T, Savage AK, Hobbs R, Gounari F, Bronson R, Pereira P, Pandolfi PP, Bendelac A, von Boehmer H. TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12453-8. Epub 2009 Jul 15. PubMed PMID: 19617548; PubMed Central PMCID: PMC2718370.


Kurshan PT, Oztan A, Schwarz TL. Presynaptic alpha2delta-3 is required forsynaptic morphogenesis independent of its Ca2+-channel functions. Nat Neurosci. 2009 Nov;12(11):1415-23. Epub 2009 Oct 11. PubMed PMID: 19820706; PubMed Central PMCID: PMC2996863.


Schwer B, Eckersdorff M, Li Y, Silva JC, Fermin D, Kurtev MV, Giallourakis C, Comb MJ, Alt FW, Lombard DB. Calorie restriction alters mitochondrial protein acetylation. Aging Cell. 2009 Sep;8(5):604-6. doi: 10.1111/j.1474-9726.2009.00503.x. Epub 2009 Jul 9. PMID: 19594485 Central PMCID: PMC2752488.  read article


Gogolla N, Leblanc JJ, Quast KB, Südhof TC, Fagiolini M, Hensch TK. Common circuit defect of excitatory-inhibitory balance in mouse models of autism. J Neurodev Disord. 2009 Jun;1(2):172-81. Epub 2009 Jul 11. PubMed PMID: 20664807; PubMed Central PMCID: PMC2906812.


Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, Asara JM. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science. 2009 May 1;324(5927):626-31. PubMed PMID: 19407199.


Tzur A, Kafri R, LeBleu VS, Lahav G, Kirschner MW. Cell growth and size homeostasis in proliferating animal cells. Science. 2009 Jul 10;325(5937):167-71. PubMed PMID: 19589995; PubMed Central PMCID: PMC2905160.


Shen X, Kim W, Fujiwara Y, Simon MD, Liu Y, Mysliwiec MR, Yuan GC, Lee Y, Orkin SH. Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells. Cell. 2009 Dec 24;139(7):1303-14. PubMed PMID: 20064376; PubMed Central PMCID: PMC2810107.


Dominy JE Jr, Lee Y, Gerhart-Hines Z, Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochim Biophys Acta. 2009 Dec 11. [Epub ahead of print] PubMed PMID: 20005308.


Chien K, Cai T, Hsu H, Su T, Chang W, Chen M, Lee Y, Hu FB. A prediction model for type 2 diabetes risk among Chinese people. Diabetologia. 2009 Mar;52(3):443-50. Epub 2008 Dec 5. PubMed PMID: 19057891.


Frueh DP, Leed A, Arthanari H, Koglin A, Walsh CT, Wagner G. Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in (15)N-(13)C-ILV methyl labeled proteins. J Biomol NMR. 2009 Nov;45(3):311-8. doi: 10.1007/s10858-009-9372-5. PMID: 19728110 PMCID: PMC2778061 read article


Yuan Z, Lehtinen MK, Merlo P, Villén J, Gygi S, Bonni A. Regulation of
neuronal cell death by MST1-FOXO1 signaling. J Biol Chem. 2009 Apr
24;284(17):11285-92. Epub 2009 Feb 16. PubMed PMID: 19221179; PubMed Central PMCID: PMC2670133.


Clatworthy AE, Lee JS, Leibman M, Kostun Z, Davidson AJ, Hung DT. Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants. Infect Immun. 2009 Apr;77(4):1293-303. doi: 10.1128/IAI.01181-08. Epub 2009 Jan 21. PMID: 19168742 PMCID: PMC2663173 read article


Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, Briken V, Moody DB. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. J Exp Med. 2009 Jun 8;206(6):1409-22. Epub 2009 May 25. Erratum in: J Exp Med. 2009 Aug 3;206(8):1831. Barral, Duarte [corrected to Barral, Duarte C]. PubMed PMID: 19468063; PubMed Central PMCID: PMC2715062.


Johnson A, Li G, Sikorski TW, Buratowski S, Woodcock CL, Moazed D*. Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell. 2009 Sep 24;35(6):769-81. PubMed PMID: 19782027; PubMed Central PMCID: PMC2842978.


Naylor ML, Li JM, Osborn AJ, Elledge SJ. Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork. Proc Natl Acad Sci USA. 2009 Aug 4;106(31):12765-70. Epub 2009 Jun 10. PubMed PMID: 19515819; PubMed Central PMCID: PMC2722297.


Li VC, Davis JC, Lenkov K, Bolival B, Fuller MT, Petrov DA. Molecular evolution of the testis TAFs of Drosophila. Mol Biol Evol. 2009 May;26(5):1103-16. doi: 10.1093/molbev/msp030. Epub 2009 Feb 25. PMID: 19244474 PMCID: PMC2727373 read article


Libedinsky C, Savage T, Livingstone M. Perceptual and physiological evidence for a role for early visual areas in motion-induced blindness. J Vis. 2009 Jan 14;9(1):14.1-10. PubMed PMID: 19271884; PubMed Central PMCID: PMC2654591.


Huynh MA, Stegmueller J, Litterman N, Bonni A. Regulation of Cdh1-APC Function in Axon Growth by Cdh1 Phosphorylation. J Neurosci. 2009 1;29(13):4322-7. PMCID: PMC2839872.


Lu A, Hiltunen M, Romano DM, Soininen H, Hyman BT, Bertram L, Tanzi RE. Effects of ubiquilin 1 on the unfolded protein response. J Mol Neurosci. 2009 May;38(1):19-30. Epub 2008 Oct 25. PubMed PMID: 18953672.


Lu J, Min W, Conchello JA, Xie XS, Lichtman JW. Super-resolution laser scanning microscopy through spatiotemporal modulation. Nano Lett. 2009 Nov;9(11):3883-9. PubMed PMID: 19743870; PubMed Central PMCID: PMC2783786.


Lu J, Fiala JC, Lichtman JW. Semi-automated reconstruction of neural processes from large numbers of fluorescence images. PLoS One. 2009 May 21;4(5):e5655. PubMed PMID: 19479070; PubMed Central PMCID: PMC2682575.


Lu J, Tapia JC, White OL, Lichtman JW. The interscutularis muscle connectome. PLoS Biol. 2009 Feb 10;7(2):e32. Erratum in: PLoS Biol. 2009 Apr;7(4):e1000108. PubMed PMID: 19209956; PubMed Central PMCID: PMC2637925.


Maimon G, Assad JA. Beyond Poisson: increased spike-time regularity across primate parietal cortex. Neuron. 2009 May 14;62(3):426-40. PubMed PMID: 19447097; PubMed Central PMCID: PMC2743683.


Maimon G, Assad JA. A cognitive signal for the proactive timing of action in macaque LIP. Nat Neurosci. 2006 Jul;9(7):948-55. Epub 2006 Jun 4. PubMed PMID: 16751764.


Gordon WR, Vardar-Ulu D, L'Heureux S, Ashworth T, Malecki MJ, Sanchez-Irizarry C, McArthur DG, Histen G, Mitchell JL, Aster JC, Blacklow SC. Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2. PLoS One. 2009 Aug 24;4(8):e6613. doi: 10.1371/journal.pone.0006613. PMID: 19701457 PMCID: PMC2726630 read article


Manuel ER, Yeh WW, Seaman MS, Furr K, Lifton MA, Hulot SL, Autissier P, Letvin NL. Dominant CD8+ T-lymphocyte responses suppress expansion of vaccine-elicited subdominant T lymphocytes in rhesus monkeys challenged with pathogenic simian-human immunodeficiency virus. J Virol. 2009 Oct;83(19):10028-35. Epub 2009 Jul 29. PMID: 19641002 PMCID: PMC2748023 read article


Hulot SL, Seaman MS, Sen P, Autissier PA, Manuel ER, Letvin NL. Diverse cross-reactive potential and Vbeta gene usage of an epitope-specific cytotoxic T-lymphocyte population in monkeys immunized with diverse human immunodeficiency virus type 1 Env immunogens. J Virol. 2009 Oct;83(19):9803-12. Epub 2009 Jul 29. PMID: 19640988 PMCID: PMC2748000 read article


McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. J Immunol. 2009 Sep 15;183(6):4067-76. doi: 10.4049/jimmunol.0801888. Epub 2009 Aug 17. PMID: 19687098 PMCID: PMC2795331 read article


Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science. 2009 Oct 9;326(5950):257-63. Epub 2009 Sep 3. PMID: 19729616 PMCID: PMC2879337 read article


McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. J Immunol. 2009 Sep 15;183(6):4067-76. Epub 2009 Aug 17. PMID: 19687098. PMCID: PMC2795331.


Brencic A, McFarland KA, McManus HR, Castang S, Mogno I, Dove SL, Lory S. The GacS/GacA signal transduction system of Pseudomonas aeruginosa acts exclusively through its control over the transcription of the RsmY and RsmZ regulatory small RNAs. Mol Microbiol. 2009 Aug;73(3):434-45. doi: 10.1111/j.1365-2958.2009.06782.x. Epub 2009 Jul 9. PMID: 19602144 PMCID: PMC2761719 read article


Haim H, Si Z, Madani N, Wang L, Courter JR, Princiotto A, Kassa A, DeGrace M, McGee-Estrada K, Mefford M, Gabuzda D, Smith AB 3rd, Sodroski J. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathog. 2009 Apr;5(4):e1000360. Epub 2009 Apr 3. PMID: 19343205 PMCID: PMC2655723 read article


Chiara DC, Hamouda AK, Ziebell MR, Mejia LA, Garcia G 3rd, Cohen JB. [(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel. Biochemistry. 2009 Oct 27;48(42):10066-77. PubMed PMID: 19754159; PubMed Central PMCID: PMC2878666.


Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 2009 Jun 5;4(6):559-67. PMID: 19497284. PMCID: PMC3065323. NIHMSID: NIHMS189973


Mitra D, Fisher DE. Transcriptional regulation in melanoma. Hematol Oncol Clin North Am. 2009 Jun;23(3):447-65, viii. doi: 10.1016/j.hoc.2009.03.003. PMID: 19464596


Molyneaux BJ***, Arlotta P***, Fame RM, MacDonald JL, MacQuarrie KL, Macklis JD. Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons. J Neurosci. 2009 Sep 30;29(39):12343-54. PMID: 19793993; PubMed Central PMCID: PMC2776075. ***Denotes equal contributions


Morris ZS, McClatchey AI. The neurofibroma cell of origin: SKPs expand the playing field. Cell Stem Cell. 2009 May 8;4(5):371-2. doi: 10.1016/j.stem.2009.04.010. PMID: 19427284


Morris ZS, McClatchey AI. Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9767-72. doi: 10.1073/pnas.0902031106. Epub 2009 Jun 1. PMID: 19487675 PMCID: PMC2700996 read article


Myoga MH, Beierlein M, Regehr WG. Somatic spikes regulate dendritic signaling in small neurons in the absence of backpropagating action potentials. J Neurosci. 2009 Jun 17;29(24):7803-14. PubMed PMID: 19535592; PubMed Central PMCID: PMC2840263.


Naylor ML, Li JM, Osborn AJ, Elledge SJ. Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork. Proc Natl Acad Sci USA. 2009 Aug 4;106(31):12765-70. Epub 2009 Jun 10. PubMed PMID: 19515819; PubMed Central PMCID: PMC2722297.


Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R,Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL. Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia. Hum Mol Genet. 2009 Feb 1;18(3):497-516. Epub 2008 Nov 7. PubMed PMID: 18996916; PubMed Central PMCID: PMC2722192.


Ng MR, Brugge JS. A stiff blow from the stroma: collagen crosslinking drives tumor progression. Cancer Cell. 2009 Dec 8;16(6):455-7. doi: 10.1016/j.ccr.2009.11.013. PMID: 19962663


Ng SY, Yoshida T, Zhang J, Georgopoulos K. Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity. 2009 Apr 17;30(4):493-507. Epub 2009 Apr 2. PubMed PMID: 19345118; PubMed Central PMCID: PMC3012962.


Engelman A, Oztop I, Vandegraaff N, Raghavendra NK. Quantitative analysis of HIV-1 preintegration complexes. Methods. 2009 Apr;47(4):283-90. doi: 10.1016/j.ymeth.2009.02.005. Epub 2009 Feb 20. PMID: 19233280 PMCID: PMC2673482 read article


Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ, Mayhall EA, Amsterdam AH, Zon LI. A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 2009 Jun 4;113(23):5776-82. doi: 10.1182/blood-2008-12-193607. Epub 2009 Mar 30. PMID: 19332767 PMCID: PMC2700318 read article


Hovav AH, Santosuosso M, Bivas-Benita M, Plair A, Cheng A, Elnekave M, Righi E, Chen T, Kashiwagi S, Panas MW, Xiang SH, Furmanov K, Letvin NL, Poznansky MC X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens..J Virol. 2009 Nov;83(21):10941-50. Epub 2009 Aug 19.PMID:19692474. PMCID: PMC2772807.


Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nat Struct Mol Biol. 2009 Oct;16(10):1021-5. Epub 2009 Aug 27. PubMed PMID: 19713958; PubMed Central PMCID: PMC2758923.


de la Iglesia N, Puram SV, Bonni A. STAT3 regulation of glioblastoma pathogenesis. Curr Mol Med. 2009 Jun;9(5):580-90. PMID: 19601808 PMCID: PMC2712135 read article


Kim AH, Puram SV, Bilimoria PM, Ikeuchi Y, Keough S, Wong M, Rowitch D, Bonni A. A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons. Cell. 2009 Jan 23;136(2):322-36. doi: 10.1016/j.cell.2008.11.050. PMID: 19167333 PMCID: PMC2707082 read article


Gogolla N, Leblanc JJ, Quast KB, Südhof TC, Fagiolini M, Hensch TK. Common circuit defect of excitatory-inhibitory balance in mouse models of autism. J Neurodev Disord. 2009 Jun;1(2):172-81. Epub 2009 Jul 11. PubMed PMID: 20664807; PubMed Central PMCID: PMC2906812.


Raiser DM, Kim CF. Commentary: Sca-1 and Cells of the Lung: A matter of Different Sorts. Stem Cells. 2009 Mar;27(3):606-11. doi: 10.1002/stem.10. PMID: 19259938 PMCID: PMC3408081 read article


Rappley I, Myers DS, Milne SB, Ivanova PT, LaVoie MJ, Brown HA, Selkoe DJ. Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with α-synuclein genotype. J Neurochem. 2009. 111:15-25. PMCID: PMC2752313.


Rappley I, Gitler AD, Selvy PE, LaVoie MJ, Levy BD, Brown HA, Lindquist S, Selkoe DJ. Evidence that α-synuclein does not inhibit phospholipase D. Biochemistry. 2009. 48: 1077-1083. PMCID: PMC2683767.


Chan EM, Ratanasirintrawoot S, Park IH, Manos PD, Loh YH, Huo H, Miller JD, Hartung O, Rho J, Ince TA, Daley GQ, Schlaeger TM. Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotechnol. 2009 Nov;27(11):1033-7. doi: 10.1038/nbt.1580. Epub 2009 Oct 11. PMID: 19826408


Reynoso ED, Turley SJ. Unconventional antigen-presenting cells in the induction of peripheral CD8(+) T cell tolerance. J Leukoc Biol. 2009 Oct;86(4):795-801. Epub 2009 Aug 3. Review. PubMed PMID: 19652027.


Reynoso ED, Elpek KG, Francisco L, Bronson R, Bellemare-Pelletier A, Sharpe AH, Freeman GJ, Turley SJ. Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade. J Immunol. 2009 Feb 15;182(4):2102-12. PubMed PMID: 19201863.


Reynoso ED, Lee JW, Turley SJ. Peripheral tolerance induction by lymph node stroma. Adv Exp Med Biol. 2009;633:113-27. Review. PubMed PMID: 19209685.


Rhee DY, Zhao XQ, Francis RJ, Huang GY, Mably JD, Lo CW. Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development. Development. 2009 Sep;136(18):3185-93. doi: 10.1242/dev.032334. PMID: 19700622 PMCID: PMC2730372 read article


Robinson KC, Fisher DE. Specification and loss of melanocyte stem cells. Semin Cell Dev Biol. 2009 Feb;20(1):111-6. doi: 10.1016/j.semcdb.2008.11.016. Epub 2008 Dec 13. PMID: 19124082


Rosen JN, Sweeney MF, Mably JD. Microinjection of zebrafish embryos to analyze gene function. J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115. PubMed PMID: 19274045.


Sage PT, Carman CV. Settings and mechanisms for trans-cellular diapedesis. Front Biosci. 2009 Jun 1;14:5066-83.


Sauvageot CM, Weatherbee JL, Kesari S, Winters SE, Barnes J, Dellagatta J,
Ramakrishna NR, Stiles CD, Kung AL, Kieran MW, Wen PY. Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells. Neuro Oncol. 2009 Apr;11(2):109-21. Epub 2008 Aug 5. PubMed PMID: 18682579; PubMed Central PMCID: PMC2718982.


Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ. A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell. 2009 May 29;137(5):835-48. PubMed PMID: 19490893; PubMed Central PMCID: PMC2768667.


Xu Q, Schlabach MR, Hannon GJ, Elledge SJ. Design of 240,000 orthogonal 25mer DNA barcode probes. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2289-94. Epub 2009 Jan 26. PubMed PMID: 19171886; PubMed Central PMCID: PMC2631075.


Schneiderman JI, Sakai A, Goldstein S, Ahmad K*. The XNP remodeler targets dynamic chromatin in Drosophila. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14472-7. Epub 2009 Aug 11. PubMed PMID: 19706533; PubMed Central PMCID: PMC2725014.


Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM. Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life. Neurobiol Dis. 2009 Nov;36(2):293-302. Epub 2009 Aug 4. PubMed PMID: 19660551; PubMed Central PMCID: PMC2782414.


Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron. 2009 Jun 25;62(6):788-801. PubMed PMID: 19555648; PubMed Central PMCID: PMC2702854.


Sikorski TW, Buratowski S. The basal initiation machinery: beyond the general transcription factors. Curr Opin Cell Biol. 2009 Jun;21(3):344-51. doi: 10.1016/j.ceb.2009.03.006. Epub 2009 May 4. PMID: 19411170 PMCID: PMC2692371 read article


Johnson A, Li G, Sikorski TW, Buratowski S, Woodcock CL, Moazed D. Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell. 2009 Sep 24;35(6):769-81. doi: 10.1016/j.molcel.2009.07.030. PMID: 19782027 PMCID: PMC2842978 read article


Sims JS, Militello KT, Sims PA, Patel VP, Kasper JM, Wirth DF. Patterns of gene-specific and total transcriptional activity during the Plasmodium falciparum intraerythrocytic developmental cycle. Eukaryot Cell. 2009 Mar;8(3):327-38. doi: 10.1128/EC.00340-08. Epub 2009 Jan 16. PMID: 19151330 PMCID: PMC2653245 read article


Higley MJ, Soler-Llavina GJ, Sabatini BL. Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration. Nat Neurosci. 2009 Sep;12(9):1121-8. Epub 2009 Aug 9. PubMed PMID: 19668198; PubMed Central PMCID: PMC2733934.


Sturgill JF, Steiner P, Czervionke BL, Sabatini BL. Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking. J Neurosci. 2009 Oct 14;29(41):12845-54. PubMed PMID: 19828799; PubMed Central PMCID: PMC2787089.


Iyer LM, Tahiliani M, Rao A, Aravind L. Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle (2009) 8(11): 1698-1710. PMID: 19411852. PMCID: PMC2995806.


Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by the MLL fusion partner, TET1. Science (2009) 324 (5929): 930-5. PMID: 19372391. PMCID: PMC2715015.


Tanner NA, Loparo JJ, van Oijen AM. Visualizing Single-molecule DNA Replication with Fluorescence Microscopy. J Vis Exp. 2009 Oct 9;(32). pii: 1529. doi: 10.3791/1529. PMID: 19820685 PMCID: PMC3142874 read article


Tanner NA, van Oijen AM. Single-molecule observation of prokaryotic DNA replication. Methods Mol Biol. 2009;521:397-410. doi: 10.1007/978-1-60327-815-7_22. PMID: 19563119 PMCID: PMC2943766 read article


Tanner NA, Loparo JJ, Hamdan SM, Jergic S, Dixon NE, van Oijen AM. Real-time single-molecule observation of rolling-circle DNA replication. Nucleic Acids Res. 2009 Mar;37(4):e27. doi: 10.1093/nar/gkp006. Epub 2009 Jan 20. PMID: 19155275 PMCID: PMC2651787 read article


Medoff BD, Seung E, Hong S, Thomas SY, Sandall BP, Duffield JS, Kuperman DA, Erle DJ, Luster AD. CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J Immunol. 2009 Jan 1;182(1):623-35. PMID: 19109196 PMCID: PMC2718444 read article


McNaughton BR, Cronican JJ, Thompson DB, Liu DR. Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6111-6. doi: 10.1073/pnas.0807883106. Epub 2009 Mar 23. PMID: 19307578 PMCID: PMC2659711 read article


Freiwald WA, Tsao DY, Livingstone MS. A face feature space in the macaque temporal lobe. Nat Neurosci. 2009 Sep;12(9):1187-96. Epub 2009 Aug 9. PubMed PMID: 19668199; PubMed Central PMCID: PMC2819705.


Uzri D, Gehrke L. Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities. J Virol. 2009 May;83(9):4174-84. Epub 2009 Feb 18. PMID: 19224987 PMCID: PMC2668486 read article


Riccio A, Li Y, Moon J, Kim KS, Smith KS, Rudolph U, Gapon S, Yao GL, Tsvetkov E, Rodig SJ, Van't Veer A, Meloni EG, Carlezon WA Jr, Bolshakov VY, Clapham DE. Essential role for TRPC5 in amygdala function and fear-related behavior. Cell. 2009 May 15;137(4):761-72. PMCID: .


Chen Z, Vijayan S, Barbieri R, Wilson MA, Brown EN. Discrete- and continuous-time probabilistic models and algorithms for inferring neuronal UP and DOWN states. Neural Comput. 2009 Jul;21(7):1797-862. PubMed PMID: 19323637; PubMed Central PMCID: PMC2799196.


Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, Khalil A, Rheinwald JG, Hochedlinger K. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature. 2009 Aug 27;460(7259):1145-8. doi: 10.1038/nature08285. Epub 2009 Aug 9. PMID: 19668190 PMCID: PMC3987892 read article


Zhang X, Rice K, Wang Y, Chen W, Zhong Y, Nakayama Y, Zhou Y, Klibanski A. Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions. Endocrinology. 2010 Mar;151(3):939-47. doi: 10.1210/en.2009-0657. Epub 2009 Dec 23. PMID: 20032057 PMCID: PMC2840681 read article


Cornejo MG, Kharas MG, Werneck MB, Le Bras S, Moore SA, Ball B, Beylot-Barry M, Rodig SJ, Aster JC, Lee BH, Cantor H, Merlio JP, Gilliland DG, Mercher T. Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models. Blood. 2009 Mar 19;113(12):2746-54. Epub 2009 Jan 12. PubMed PMID: 19139084; PubMed Central PMCID: PMC2661862.


Fraenkel PG, Gibert Y, Holzheimer JL, Lattanzi VJ, Burnett SF, Dooley KA, Wingert RA, Zon LI. Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood. 2009 Mar 19;113(12):2843-50. doi: 10.1182/blood-2008-06-165340. Epub 2008 Dec 1. PMID: 19047682 PMCID: PMC2661867 read article


Chan JA***, Balasubramanian S***, Witt RM***, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA. Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17. Epub 2009 Mar 15. PMID: 19287388. PMCID: PMC2676236. ***Denotes equal contribution


Witt RM, Galligan MM, Despinoy JR, Segal R. Olfactory behavioral testing in the adult mouse. J Vis Exp. 2009 Jan 28;(23). pii: 949. doi: 10.3791/949. PMID: 19229182. PMCID: PMC278299.


Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA. Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses. Nat Neurosci. 2009 Apr;12(4):409-17. Epub 2009 Mar 15. PubMed PMID: 19287388; PubMed Central PMCID: PMC2676236.


Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A, Lee J, Goldfine AB, Benoist C, Shoelson S, Mathis D. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med. 2009 Aug;15(8):930-9. Epub 2009 Jul 26. PMID: 19633656. PMCID: PMC3115752.


Yang Y, Kim AH, Yamada T, Wu B, Bilimoria PM, Ikeuchi Y, de la Iglesia N, Shen J, Bonni A. A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science. 2009 Oct 23;326(5952):575-8. PubMed PMID: 19900895; PubMed Central PMCID: PMC2846784.


top

2008


Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD. SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Neuron. 2008 Jan 24;57(2):232-47. PubMed PMID: 18215621.


Abraira VE, Del Rio T, Tucker AF, Slonimsky J, Keirnes HL, Goodrich LV.Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development. 2008 Dec;135(24):4091-9. Epub 2008 Nov 12. PubMed PMID: 19004851; PubMed Central PMCID: PMC2892390.


Agosto MA, Myers KS, Ivanovic T, Nibert ML. A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10571-6. doi: 10.1073/pnas.0802039105. Epub 2008 Jul 24. PMID: 18653761 PMCID: PMC2492467 read article


Ivanovic T, Agosto MA, Zhang L, Chandran K, Harrison SC, Nibert ML. Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. EMBO J. 2008 Apr 23;27(8):1289-98. doi: 10.1038/emboj.2008.60. Epub 2008 Mar 27. PMID: 18369316 PMCID: PMC2367403 read article


Petzold GC, Albeanu DF, Sato TF, Murthy VN. Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways. Neuron. 2008 Jun 26;58(6):897-910. PubMed PMID: 18579080; PubMed Central PMCID: PMC2922004.


Albeanu DF, Soucy E, Sato TF, Meister M, Murthy VN. LED arrays as cost effective and efficient light sources for widefield microscopy. PLoS One. 2008 May 14;3(5):e2146. PubMed PMID: 18478056; PubMed Central PMCID: PMC2361193.


Anderson SB, Goldberg AL, Whitman M. Identification of a novel pool of extracellular pro-myostatin in skeletal muscle. J Biol Chem. 2008 Mar 14;283(11):7027-35. doi: 10.1074/jbc.M706678200. Epub 2008 Jan 6. PMID: 18175804


Gordon WR, Arnett KL, Blacklow SC. The molecular logic of Notch signaling-a structural and biochemical perspective. J Cell Sci. 2008 Oct 1;121(Pt 19):3109-19. Review. PubMed PMID: 18799787; PubMed Central PMCID: PMC2696053.


Arnold MM, Murray KE, Nibert ML. Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein mu NS during reovirus infection. Virology. 2008 Jun 5;375(2):412-23. Epub 2008 Apr 18. PMID: 18374384 PMCID: PMC2486453 read article


Atkins BD, Yoshida S, Pellman D. Symmetry breaking: scaffold plays matchmaker for polarity signaling proteins. Curr Biol. 2008 Dec 23;18(24):R1130-2. doi: 10.1016/j.cub.2008.11.005. PMID: 19108767


Balibar CJ, Walsh CT. From thioesters to amides and back: condensation domain reversibility in the biosynthesis of vibriobactin. Chembiochem. 2008 Jan 4;9(1):42-5. PMID: 18022888


Ryan KS, Balibar CJ, Turo KE, Walsh CT, Drennan CL. The violacein biosynthetic enzyme VioE shares a fold with lipoprotein transporter proteins. J Biol Chem. 2008 Mar 7;283(10):6467-75. doi: 10.1074/jbc.M708573200. Epub 2008 Jan 2. PMID: 18171675


Villén J, Beausoleil SA, Gygi SP. Evaluation of the utility of neutral-loss-dependent MS3 strategies in large-scale phosphorylation analysis. Proteomics. 2008 Nov;8(21):4444-52. doi: 10.1002/pmic.200800283. PMID: 18972524 PMCID: PMC2745099 read article


Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP. A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31. PMID: 18669648 PMCID: PMC2504835 read article


Zhai B, Villén J, Beausoleil SA, Mintseris J, Gygi SP. Phosphoproteome analysis of Drosophila melanogaster embryos. J Proteome Res. 2008 Apr;7(4):1675-82. doi: 10.1021/pr700696a. Epub 2008 Mar 8. PMID: 18327897 PMCID: PMC3063950 read article


Bilimoria PM, Bonni A. Cultures of Cerebellar Granule Neurons. CSH Protoc.2008;13:5107. PubMed PMID: 21152358; PubMed Central PMCID: PMC2996826.


Vig M, Dehaven WI, Bird GS, Billingsley JM, Wang H, Rao PE, Hutchings AB, Jouvin MH, Putney JW, Kinet JP. 2008. Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. Nat. Immunol. 9(1); 89-96. PMCID: PMC2377025.


Lin Y, Bloodgood BL, Hauser JL, Lapan AD, Koon AC, Kim TK, Hu LS, Malik AN, Greenberg ME. Activity-dependent regulation of inhibitory synapse development by Npas4. Nature. 2008 Oct 30;455(7217):1198-204. Epub 2008 Sep 24. PubMed PMID: 18815592; PubMed Central PMCID: PMC2637532.


Franco S, Murphy MM, Li G, Borjeson T, Boboila C, Alt FW. DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination. J Exp Med. 2008 Mar 17;205(3):557-64. Epub 2008 Mar 3. PubMed PMID: 18316419; PubMed Central PMCID: PMC2275379.


Cariappa A, Takematsu H, Liu H, Diaz S, Haider K, Boboila C, Kalloo G, Connole M, Shi HN, Varki N, Varki A, Pillai S. B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase. J Exp Med. 2009 Jan 16;206(1):125-38. Epub 2008 Dec 22. PubMed PMID: 19103880; PubMed Central PMCID: PMC2626685.


Bortnick RA, Gaufberg E. Injustice. Med Educ. 2008 Nov;42(11):1108-9. PubMed PMID: 19141010.


Rowley CF, Boutwell CL, Lockman S, Essex M. Improvement in allele-specific PCR assay with the use of polymorphism-specific primers for the analysis of minor variant drug resistance in HIV-1 subtype C. J Virol Methods. 2008 Apr;149(1):69-75. doi: 10.1016/j.jviromet.2008.01.005. Epub 2008 Mar 4. PMID: 18295909 PMCID: PMC2927209 read article


Boyce M, Py BF, Ryazanov AG, Minden JS, Long K, Ma D, Yuan J. A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death. Cell Death Differ. 2008 Mar;15(3):589-99. doi: 10.1038/sj.cdd.4402296. Epub 2008 Jan 11. PMID: 18188169


Bryant KF, Macari ER, Malik N, Boyce M, Yuan J, Coen DM. ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells. Virology. 2008 Sep 30;379(2):197-204. doi: 10.1016/j.virol.2008.06.028. Epub 2008 Aug 6. PMID: 18684481 PMCID: PMC2665023 read article


Brown KM, Landry CR, Hartl DL, Cavalieri D. Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae. Mol Ecol. 2008 Jun;17(12):2985-97. Epub 2008 Apr 18. PubMed PMID: 18422925.


Buchman JJ, Tsai LH. Putting a notch in our understanding of nuclear migration. Cell. 2008 Sep 19;134(6):912-4. PubMed PMID: 18805082.


Burrows AE, Elledge SJ. How ATR turns on: TopBP1 goes on ATRIP with ATR. Genes Dev. 2008 Jun 1;22(11):1416-21. doi: 10.1101/gad.1685108. PMID: 18519633 PMCID: PMC2732414 read article


Butty V, Campbell C, Mathis D, Benoist C; DPT-1 Study Group. Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).Diabetes. 2008 Sep;57(9):2348-59. Epub 2008 Jun 12. PMID:18556337. PMCID: PMC2518486.


Johnsen AK, Plenge RM, Butty V, Campbell C, Dieguez-Gonzalez R, Gomez-Reino JJ, Shadick N, Weinblatt M, Gonzalez A, Gregersen PK, Benoist C, Mathis D. A broad analysis of IL1 polymorphism and rheumatoid arthritis. Arthritis Rheum. 2008 Jul;58(7):1947-57. PMID:18576312. PMCID: PMC2533126.


Xu C, Gagnon E, Call ME, Schnell JR, Schwieters CD, Carman CV, Chou JJ, Wucherpfennig KW. Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif. Cell. 2008 Nov 14;135(4):702-13. PubMed PMID: 19013279; PubMed Central PMCID: PMC2597348.


Catapano LA, Magavi SS, Macklis JD. Neuroanatomical tracing of neuronal projections with Fluoro-Gold. Methods Mol Biol. 2008;438:353-9. PubMed PMID: 18369770.


Cedeno-Laurent F, Bryant J, Fishelevich R, Jones OD, Deng A, Eng ML, Gaspari AA, Trujillo JR. Inflammatory papillomatous hyperplasia and epidermal necrosis in a transgenic rat for HIV-1. J Dermatol Sci. 2009 Feb;53(2):112-9. Epub 2008 Nov 11. PubMed PMID: 19004620; PubMed Central PMCID: PMC3125122.


Hett EC, Chao MC, Deng LL, Rubin EJ. A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor. PLoS Pathog. 2008 Feb 29;4(2):e1000001. PubMed PMID: 18463693; PubMed Central PMCID: PMC2262848.


Young-Pearse TL, Chen AC, Chang R, Marquez C, Selkoe DJ. Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. Neural Dev. 2008 Jun 23;3:15. PubMed PMID: 18573216; PubMed Central PMCID: PMC2442059.


Cheung V, Chua G, Batada NN, Landry CR, Michnick SW, Hughes TR, Winston F. Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. PLoS Biol. 2008 Nov 11;6(11):e277. PubMed PMID: 18998772; PubMed Central PMCID: PMC2581627.


Chiang CW, Derti A, Schwartz D, Chou MF, Hirschhorn JN, Wu CT. Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries. Genetics. 2008 Dec;180(4):2277-93. Epub 2008 Oct 28. PubMed PMID: 18957701; PubMed Central PMCID: PMC2600958.


Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One. 2008;3(10):e3583. Epub 2008 Oct 31. PubMed PMID: 18974833; PubMed Central PMCID: PMC2571995.


Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, Vartanian TK, Brown RH Jr, Carroll MC. T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17913-8. Epub 2008 Nov 7. PMID: 18997009. PMCID: PMC2581614.


Cutler C, Stevenson K, Kim HT, Richardson P, Ho VT, Linden E, Revta C, Ebert R, Warren D, Choi S, Koreth J, Armand P, Alyea E, Carter S, Horowitz M, Antin JH, Soiffer R. Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation. Blood. 2008 Dec 1;112(12):4425-31. Epub 2008 Sep 5. PubMed PMID: 18776081; PubMed Central PMCID: PMC2597119.


Mitnick CD, Shin SS, Seung KJ, Rich ML, Atwood SS, Furin JJ, Fitzmaurice GM, Alcantara Viru FA, Appleton SC, Bayona JN, Bonilla CA, Chalco K, Choi S, Franke MF, Fraser HS, Guerra D, Hurtado RM, Jazayeri D, Joseph K, Llaro K, Mestanza L, Mukherjee JS, Muñoz M, Palacios E, Sanchez E, Sloutsky A, Becerra MC. Comprehensive treatment of extensively drug-resistant tuberculosis. N Engl J Med. 2008 Aug 7;359(6):563-74. PubMed PMID: 18687637; PubMed Central PMCID: PMC2673722.


Liu M, Choi S, Cuny GD, Ding K, Dobson BC, Glicksman MA, Auerbach K, Stein RL. Kinetic studies of Cdk5/p25 kinase: phosphorylation of tau and complex inhibition by two prototype inhibitors. Biochemistry. 2008 Aug 12;47(32):8367-77. Epub 2008 Jul 18. PubMed PMID: 18636751.


Chiang CW, Derti A, Schwartz D, Chou MF, Hirschhorn JN, Wu CT. Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries. Genetics. 2008 Dec;180(4):2277-93. Epub 2008 Oct 28. PubMed PMID: 18957701; PubMed Central PMCID: PMC2600958.


Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell. 2008 Dec 26;135(7):1311-23. doi: 10.1016/j.cell.2008.10.044. PMID: 19109899 PMCID: PMC2621059 read article


Chun DK, McEwen JM, Burbea M, Kaplan JM. UNC-108/Rab2 regulates postendocytic trafficking in Caenorhabditis elegans. Mol Biol Cell. 2008 Jul;19(7):2682-95. doi: 10.1091/mbc.E07-11-1120. Epub 2008 Apr 23. PMID: 18434599 PMCID: PMC2441656 read article


Dickinson BL, Claypool SM, Aiken ML, D'Angelo JA, Venu N, Yen EH, Wagner JS, Borawski JA, Pierce AT, Hershberg R, Blumberg RS, Lencer WI. Ca2+-dependent calmodulin-binding to FcRn sorts between the transcytotic and lysosomal pathways. Mol Biol Cell. 2008 Jan;19(1):414-23. PMCID: PMC2174181.


Leadbetter EA, Brigl M, Illarionov P, Cohen N, Luteran MC, Pillai S, Besra GS, Brenner MB. NK T cells provide lipid antigen-specific cognate help for B cells. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8339-44. Epub 2008 Jun 11. PMID: 18550809 PMCID: PMC2448838


Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11281-6. Epub 2008 Aug 6. PMID: 18685099 PMCID: PMC2516216


Kindler T, Cornejo MG, Scholl C, Liu J, Leeman DS, Haydu JE, Fröhling S, Lee BH, Gilliland DG. K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to gamma-secretase inhibitors. Blood. 2008 Oct 15;112(8):3373-82. Epub 2008 Jul 28. PubMed PMID: 18663146; PubMed Central PMCID: PMC2569181.


Costantino CM, Hang HC, Kent SC, Hafler DA, Ploegh HL. Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation. J Immunol. 2008 Mar 1;180(5):2876-85. PubMed PMID: 18292509.


Costantino CM, Baecher-Allan C, Hafler DA. Multiple sclerosis and regulatory T cells. J Clin Immunol. 2008 Nov;28(6):697-706. Epub 2008 Sep 2. Review. PubMed PMID: 18763026; PubMed Central PMCID: PMC2752287.


Costantino CM, Baecher-Allan CM, Hafler DA. Human regulatory T cell and autoimmunity. Eur J Immunol. 2008 Apr;38(4):921-4. Review. PubMed PMID: 18395861; PubMed Central PMCID: PMC2752283.


Cosker KE, Courchesne SL, Segal RA. Action in the axon: generation and transport of signaling endosomes. Curr Opin Neurobiol. 2008 Jun;18(3):270-5. Review. PubMed PMID: 18778772; PubMed Central PMCID: PMC2693191.


Raiser DM, Zacharek SJ, Roach RR, Curtis SJ, Sinkevicius KW, Gludish DW, Kim CF. Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches. Cold Spring Harb Symp Quant Biol. 2008;73:479-90. Epub 2008 Nov 21. Review. PubMed PMID: 19028984.


Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A,Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE. Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses. Nat Neurosci. 2008 Apr;11(4):476-87. Epub 2008 Mar 23. PubMed PMID: 18344994; PubMed Central PMCID: PMC2556874.


Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA. Evolution of the aging brain transcriptome and synaptic regulation. PLoS One. 2008 Oct 2;3(10):e3329. PubMed PMID: 18830410; PubMed Central PMCID: PMC2553198.


Day CL, Mkhwanazi N, Reddy S, Mncube Z, van der Stok M, Klenerman P, Walker BD. Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons. J Infect Dis. 2008 Apr 1;197(7):990-9. doi: 10.1086/529048. PMID: 18419535


Ramduth D, Thobakgale CF, Mkhwanazi NP, De Pierres C, Reddy S, van der Stok M, Mncube Z, Mphatswe W, Blanckenberg N, Cengimbo A, Prendergast A, Tudor-Williams G, Dong K, Jeena P, Coovadia HM, Day CL, Kiepiela P, Goulder PJ, Walker BD. Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants. AIDS Res Hum Retroviruses. 2008 Feb;24(2):265-70. doi: 10.1089/aid.2007.0096. PMID: 18284325


Ngumbela KC, Day CL, Mncube Z, Nair K, Ramduth D, Thobakgale C, Moodley E, Reddy S, de Pierres C, Mkhwanazi N, Bishop K, van der Stok M, Ismail N, Honeyborne I, Crawford H, Kavanagh DG, Rousseau C, Nickle D, Mullins J, Heckerman D, Korber B, Coovadia H, Kiepiela P, Goulder PJ, Walker BD. Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure. AIDS Res Hum Retroviruses. 2008 Jan;24(1):72-82. doi: 10.1089/aid.2007.0124. PMID: 18275350


de la Torre-Ubieta L, Bonni A. Combinatorial assembly of neurons: from chromatin to dendrites. Trends Cell Biol. 2008 Feb;18(2):48-51. Epub 2008 Jan 28. PubMed PMID: 18222691.


Dougan M, Dranoff G. Inciting inflammation: the RAGE about tumor promotion.J Exp Med. 2008 Feb 18;205(2):267-70. Epub 2008 Feb 11. PMID: 18268042


Hussain MM, Rava P, Pan X, Dai K, Dougan SK, Iqbal J, Lazare F, Khatun I. Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism. Curr Opin Lipidol. 2008 Jun;19(3):277-84. Review. PubMed PMID: 18460919.


White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, Bourque C, Dovey M, Goessling W, Burns CE, Zon LI. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell. 2008 Feb 7;2(2):183-9. doi: 10.1016/j.stem.2007.11.002. PMID: 18371439 PMCID: PMC2292119 read article


Jinushi M, Nakazaki Y, Carrasco DR, Draganov D, Souders N, Johnson M, Mihm MC,Dranoff G. Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. Cancer Res. 2008 Nov 1;68(21):8889-98. PubMed PMID: 18974133.


Dallabrida SM, Ismail NS, Pravda EA, Parodi EM, Dickie R, Durand EM, Lai J,Cassiola F, Rogers RA, Rupnick MA. Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J. 2008 Aug;22(8):3010-23. Epub 2008 May 23. PubMed PMID: 18502941; PubMed Central PMCID: PMC2493452.


Dutton RJ, Boyd D, Berkmen M, Beckwith J. Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11933-8. Epub 2008 Aug 11. PubMed PMID: 18695247; PubMed Central PMCID: PMC2575290.


Erlandson KJ, Or E, Osborne AR, Rapoport TA. Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. J Biol Chem. 2008 Jun 6;283(23):15709-15. Epub 2008 Mar 21. PMID: 18359943 PMCID: PMC2409214 read article


Erlandson KJ, Miller SB, Nam Y, Osborne AR, Zimmer J, Rapoport TA. A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 2008 Oct 16;455(7215):984-7. PMID: 18923526


Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT. Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science. 2008 Oct 31;322(5902):750-6. PubMed PMID: 18974356; PubMed Central PMCID: PMC2748911.


Erwin JA, Lee JT. New twists in X-chromosome inactivation. Curr Opin Cell Biol. 2008 Jun;20(3):349-55. Epub 2008 May 26. Review. PubMed PMID: 18508252; PubMed Central PMCID: PMC2491718.


Bakalarski CE, Elias JE, Villén J, Haas W, Gerber SA, Everley PA, Gygi SP. The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses. J Proteome Res. 2008 Nov;7(11):4756-65. doi: 10.1021/pr800333e. Epub 2008 Sep 18. PMID: 18798661 PMCID: PMC2746028


Fantana AL, Soucy ER, Meister M. Rat olfactory bulb mitral cells receive sparse glomerular inputs. Neuron. 2008 Sep 11;59(5):802-14. PubMed PMID: 18786363.


Heng TS, Painter MW; Immunological Genome Project Consortium (Elpek K, Lukacs-Kornek V, Mauermann N, Turley SJ, Koller D, Kim FS, Wagers AJ, Asinovski N, Davis S, Fassett M, Feuerer M, Gray DH, Haxhinasto S, Hill JA, Hyatt G, Laplace C, Leatherbee K, Mathis D, Benoist C, Jianu R, Laidlaw DH, Best JA, Knell J, Goldrath AW, Jarjoura J, Sun JC, Zhu Y, Lanier LL, Ergun A, Li Z, Collins JJ, Shinton SA, Hardy RR, Friedline R, Sylvia K, Kang J.) The Immunological Genome Project: networks of gene expression in immune cells.Nat Immunol. 2008 Oct;9(10):1091-4.PMID: 18800157


Flavell SW, Kim TK, Gray JM, Harmin DA, Hemberg M, Hong EJ, Markenscoff-Papadimitriou E, Bear DM, Greenberg ME. Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron. 2008 Dec 26;60(6):1022-38. PubMed PMID: 19109909; PubMed Central PMCID: PMC2630178.


Morrow EM, Yoo SY, Flavell SW, Kim TK, Lin Y, Hill RS, Mukaddes NM, Balkhy S, Gascon G, Hashmi A, Al-Saad S, Ware J, Joseph RM, Greenblatt R, Gleason D, Ertelt JA, Apse KA, Bodell A, Partlow JN, Barry B, Yao H, Markianos K, Ferland RJ, Greenberg ME, Walsh CA. Identifying autism loci and genes by tracing recent shared ancestry. Science. 2008 Jul 11;321(5886):218-23. Erratum in: Science. 2010 Dec 24;330(6012):1746. PubMed PMID: 18621663; PubMed Central PMCID: PMC2586171.


Flavell SW, Greenberg ME. Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system. Annu Rev Neurosci. 2008;31:563-90. Review. PubMed PMID: 18558867; PubMed Central PMCID: PMC2728073.


Fontaine-Rodriguez EC, Knipe DM. Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs. J Virol. 2008 Apr;82(7):3538-45. Epub 2008 Jan 23. PMID: 18216091 PMCID: PMC2268449 read article


Paleologou KE, Schmid AW, Rospigliosi CC, Kim HY, Lamberto GR, Fredenburg RA, Lansbury PT Jr, Fernandez CO, Eliezer D, Zweckstetter M, Lashuel HA. Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. J Biol Chem. 2008 Jun 13;283(24):16895-905. doi: 10.1074/jbc.M800747200. Epub 2008 Mar 14. PMID: 18343814 PMCID: PMC2423264 read article


Gabel HW, Ruvkun G. The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi. Nat Struct Mol Biol. 2008 May;15(5):531-3. Epub 2008 Apr 27. PubMed PMID: 18438419.


Pierce ML, Weston MD, Fritzsch B, Gabel HW, Ruvkun G, Soukup GA. MicroRNA-183 family conservation and ciliated neurosensory organ expression. Evol Dev. 2008 Jan-Feb;10(1):106-13. PubMed PMID: 18184361; PubMed Central PMCID: PMC2637451.


Gajdos ZK, Butler JL, Henderson KD, He C, Supelak PJ, Egyud M, Price A, Reich D, Clayton PE, Le Marchand L, Hunter DJ, Henderson BE, Palmert MR, Hirschhorn JN Association studies of common variants in 10 hypogonadotropic hypogonadism genes with age at menarche. J Clin Endocrinol Metab. 2008 Nov;93(11):4290-8. Epub 2008 Aug 26. PubMed PMID: 18728166; PubMed Central PMCID: PMC2582573.


Barral DC, Cavallari M, McCormick PJ, Garg S, Magee AI, Bonifacino JS, De Libero G, Brenner MB. CD1a and MHC class I follow a similar endocytic recycling pathway.Traffic. 2008 Sep;9(9):1446-57. Epub 2008 Jun 28. PMID: 18564371. PMCID: PMC3839101


Gomila RC, Gehrke L. Biochemical approaches for characterizing RNA-protein complexes in preparation for high resolution structure analysis. Methods Mol Biol. 2008;451:279-91. doi: 10.1007/978-1-59745-102-4_20. PMID: 18370263


Wilson-Grady JT, Villén J, Gygi SP. Phosphoproteome analysis of fission yeast. J Proteome Res. 2008 Mar;7(3):1088-97. doi: 10.1021/pr7006335. Epub 2008 Feb 8. PMID: 18257517


Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, Letvin NL. Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses. Clin Vaccine Immunol. 2008 Apr;15(4):691-6. Epub 2008 Feb 13. PMID: 18272665 PMCID: PMC2292663 read article


Geiben-Lynn R, Greenland JR, Frimpong-Boateng K, van Rooijen N, Hovav AH, Letvin NL. CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses. Blood. 2008 Dec 1;112(12):4585-90. Epub 2008 Sep 10. PMID: 18784371 PMCID: PMC2597129 read article


Yuan AH, Gregory BD, Sharp JS, McCleary KD, Dove SL, Hochschild A. Rsd family proteins make simultaneous interactions with regions 2 and 4 of the primary sigma factor. Mol Microbiol. 2008 Dec;70(5):1136-51. doi: 10.1111/j.1365-2958.2008.06462.x. Epub 2008 Sep 30. PMID: 18826409 PMCID: PMC2581641 read article


Kim JM, Kee Y, Gurtan A, D'Andrea AD. Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24. Blood. 2008 May 15;111(10):5215-22. doi: 10.1182/blood-2007-09-113092. Epub 2008 Jan 3. PMID: 18174376 PMCID: PMC2384144 read article


Hafler BP, Choi MY, Shivdasani RA, Rowitch DH. Expression and function of Nkx6.3 in vertebrate hindbrain. Brain Res. 2008 Jul 30;1222:42-50. Epub 2008 May 6. PubMed PMID: 18586225; PubMed Central PMCID: PMC2555971.


Trimarchi JM, Harpavat S, Billings NA, Cepko CL. Thyroid hormone components are expressed in three sequential waves during development of the chick retina. BMC Dev Biol. 2008 Oct 14;8:101. PubMed PMID: 18854032; PubMed Central PMCID: PMC2579430.


Haushofer J, Livingstone MS, Kanwisher N. Multivariate patterns in object-selective cortex dissociate perceptual and physical shape similarity. PLoS Biol. 2008 Jul 29;6(7):e187. PubMed PMID: 18666833; PubMed Central PMCID: PMC2486311.


Haushofer J, Baker CI, Livingstone MS, Kanwisher N. Privileged coding of convex shapes in human object-selective cortex. J Neurophysiol. 2008 Aug;100(2):753-62. Epub 2008 Jun 25. PubMed PMID: 18579661; PubMed Central PMCID: PMC2525726.


Op de Beeck HP, Haushofer J, Kanwisher NG. Interpreting fMRI data: maps, modules and dimensions. Nat Rev Neurosci. 2008 Feb;9(2):123-35. Review. PubMed PMID: 18200027; PubMed Central PMCID: PMC2731480.


Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 2008 May 1;22(9):1174-89. doi: 10.1101/gad.1642808. PMID: 18451107 PMCID: PMC2335314 read article


Hemming ML, Elias JE, Gygi SP, Selkoe DJ. Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements. PLoS Biol. 2008 Oct 21;6(10):e257. PubMed PMID: 18942891; PubMed Central PMCID: PMC2570425.


Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn MP, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH. T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation.Nat Immunol. 2008 Mar;9(3):282-91. Epub 2008 Jan 20. PMID: 18204450. PMCID: PMC2698867


Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn M, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH. In vivo imaging of T cell priming. Sci Signal. 2008 Mar 25;1(12):pt2. PMID: 18364513


Zheng H, Jin B, Henrickson SE, Perelson AS, von Andrian UH, Chakraborty AK. How antigen quantity and quality determine T-cell decisions in lymphoid tissue.Mol Cell Biol. 2008 Jun;28(12):4040-51. Epub 2008 Apr 21. PMID: 18426917. PMCID: PMC2423119


Hill SJ, Berkowitz R, Granter SR, Hirsch MS. Pagetoid lesions of the vulva: a collision between malignant melanoma and extramammary Paget disease.Int J Gynecol Pathol. 2008 Apr;27(2):292-6. PMID: 18317209


Flavell SW, Kim TK, Gray JM, Harmin DA, Hemberg M, Hong EJ, Markenscoff-Papadimitriou E, Bear DM, Greenberg ME. Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron. 2008 Dec 26;60(6):1022-38. PubMed PMID: 19109909; PubMed Central PMCID: PMC2630178.


Hong EJ, McCord AE, Greenberg ME. A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibition. Neuron. 2008 Nov 26;60(4):610-24. PubMed PMID: 19038219; PubMed Central PMCID: PMC2873221.


Singh KK, Park KJ, Hong EJ, Kramer BM, Greenberg ME, Kaplan DR, Miller FD. Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat Neurosci. 2008 Jun;11(6):649-58. Epub 2008 Apr 1. PubMed PMID: 18382462.


Nazer B, Hong S, Selkoe DJ. LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model. Neurobiol Dis. 2008 Apr;30(1):94-102. Epub 2008 Jan 5. PubMed PMID: 18289866; PubMed Central PMCID: PMC2376120.


Hooks BM, Chen C. Vision Triggers an Experience-Dependent Sensitive Period at the Retinogeniculate Synapse. Journal of Neuroscience. 2008. 28: 4807-17. PMCID: PMC2793334.


Stegmüller J, Huynh MA, Yuan Z, Konishi Y, Bonni A. TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis. J Neurosci. 2008 Feb 20;28(8):1961-9. doi: 10.1523/JNEUROSCI.3061-07.2008. PMID: 18287512


Sarker KP, Kataoka H, Chan A, Netherton SJ, Pot I, Huynh MA, Feng X, Bonni A, Riabowol K, Bonni S. ING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cells. J Biol Chem. 2008 May 9;283(19):13269-79. doi: 10.1074/jbc.M708834200. Epub 2008 Mar 11. PMID: 18334480 PMCID: PMC2442333 read article


Sullivan S, Ichida JK, Umezawa A, Akutsu H. Elucidating nuclear reprogramming mechanisms: taking a synergistic approach. Reprod Biomed Online. 2008 Jan;16(1):41-50. Review. PubMed PMID: 18252046.


Roesch K, Jadhav AP, Trimarchi JM, Stadler MB, Roska B, Sun BB, Cepko CL. The transcriptome of retinal Müller glial cells. J Comp Neurol. 2008 Jul 10;509(2):225-38. doi: 10.1002/cne.21730. PMID: 18465787 PMCID: PMC2665263 read article


Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci. 2008 May 7;28(19):4878-87. doi: 10.1523/JNEUROSCI.0828-08.2008. PMID: 18463241 PMCID: PMC3325486 read article


Johnson KE, Song B, Knipe DM. Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. Virology. 2008 May 10;374(2):487-94. Epub 2008 Feb 14. PMID: 18279905 PMCID: PMC2638114 read article


Courtois-Cox S, Jones SL, Cichowski K. Many roads lead to oncogene-induced senescence. Oncogene. 2008 May 1;27(20):2801-9. doi: 10.1038/sj.onc.1210950. Epub 2008 Jan 14. PMID: 18193093


Koh AS, Kuo AJ, Park SY, Cheung P, Abramson J, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, Benoist C, Mathis D. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15878-83. Epub 2008 Oct 7. PMID: 18840680 PMCID: PMC2572939


de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2008 Feb 15;22(4):449-62. Epub 2008 Feb 7. PubMed PMID: 18258752; PubMed Central PMCID: PMC2238667.


de la Iglesia N, Konopka G, Lim KL, Nutt CL, Bromberg JF, Frank DA, Mischel PS, Louis DN, Bonni A. Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. J Neurosci. 2008 Jun 4;28(23):5870-8. PubMed PMID: 18524891; PubMed Central PMCID: PMC2700037.


Mesaros A***, Koralov SB***, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC. Activation of Stat3 signaling in AgRP neurons promotes locomotor activity. Cell Metab. 2008 Mar;7(3):236-48. ***Denotes equal contribution.


Koralov SB, Muljo SA, Galler GR, Krek A, Chakraborty T, Kanellopoulou C, Jensen K, Cobb BS, Merkenschlager M, Rajewsky N, Rajewsky K. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell. 2008 Mar 7;132(5):860-74.


Kuhn, JH (Co-editor and Contributor Kranzusch, PJ pg 349). (2008) Filoviruses, A compendium of 40 years of epidemiological, clinical, and laboratory studies, Arch. Virol. Suppl. 20, 12-360. PMID: 18637412


Egawa T, Kreslavsky T, Littman DR, von Boehmer H. Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping. PLoS One. 2008 Jan 30;3(1):e1512. PubMed PMID: 18231598; PubMed Central PMCID: PMC2211402.


Kreslavsky T, Garbe AI, Krueger A, von Boehmer H. T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis. J Exp Med. 2008 May 12;205(5):1173-86. Epub 2008 Apr 28. PubMed PMID: 18443226; PubMed Central PMCID: PMC2373848.


Dickman DK, Kurshan PT, Schwarz TL. Mutations in a Drosophila alpha2delta voltage-gated calcium channel subunit reveal a crucial synaptic function. J Neurosci. 2008 Jan 2;28(1):31-8. PubMed PMID: 18171920.


Ma YC, Song MR, Park JP, Henry Ho HY, Hu L, Kurtev MV, Zieg J, Ma Q, Pfaff SL, Greenberg ME. Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron. 2008 Apr 10;58(1):65-77. doi: 10.1016/j.neuron.2008.01.037. PMID: 18400164; PMCID: PMC2587148. read article


Andersen CB, Wan Y, Chang JW, Riggs B, Lee C, Liu Y, Sessa F, Villa F, Kwiatkowski N, Suzuki M, Nallan L, Heald R, Musacchio A, Gray NS. Discovery of selective aminothiazole aurora kinase inhibitors. ACS Chem Biol. 2008 Mar 20;3(3):180-92. doi: 10.1021/cb700200w. Epub 2008 Feb 29. PMID: 18307303


Estiu G, Greenberg E, Harrison CB, Kwiatkowski NP, Mazitschek R, Bradner JE, Wiest O. Structural origin of selectivity in class II-selective histone deacetylase inhibitors. J Med Chem. 2008 May 22;51(10):2898-906. doi: 10.1021/jm7015254. Epub 2008 Apr 16. PMID: 18412327


LeBleu VS, Kalluri R. Stem cell-based therapy for glomerular diseases: an evolving concept. J Am Soc Nephrol. 2008 Sep;19(9):1621-3. Epub 2008 Aug 13. PubMed PMID: 18701605.


Lebleu VS, Sugimoto H, Miller CA, Gattone VH 2nd, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Lab Invest. 2008 Mar;88(3):284-92. Epub 2008 Jan 7. PubMed PMID: 18180701.


Radoshitzky SR, Kuhn JH, Spiropoulou CF, Albariño CG, Nguyen DP, Salazar-Bravo J, Dorfman T, Lee AS, Wang E, Ross SR, Choe H, Farzan M. Receptor determinants of zoonotic transmission of New World hemorrhagic fever arenaviruses. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2664-9. Epub 2008 Feb 11. PMID: 18268337 PMCID: PMC2268193 read article


Deighan P, Diez CM, Leibman M, Hochschild A, Nickels BE. The bacteriophage lambda Q antiterminator protein contacts the beta-flap domain of RNA polymerase. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15305-10. doi: 10.1073/pnas.0805757105. Epub 2008 Oct 1. PMID: 18832144 PMCID: PMC2563111 read article


Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11281-6. Epub 2008 Aug 6. PubMed PMID: 18685099; PubMed Central PMCID: PMC2516216.


Buchberger JR, Onishi M, Li G, Seebacher J, Rudner AD, Gygi SP, Moazed D*. Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae. Mol Cell Biol. 2008 Nov;28(22):6903-18. Epub 2008 Sep 15. PubMed PMID: 18794362; PubMed Central PMCID: PMC2573294.


Li JM, Tetzlaff MT, Elledge SJ. Identification of MSA1, a cell cycle-regulated, dosage suppressor of drc1/sld2 and dpb11 mutants. Cell Cycle. 2008 Nov 1;7(21):3388-98. Epub 2008 Nov 5. PubMed PMID: 18948746.


Li JM. Pain management in the hospitalized patient. Med Clin North Am. 2008 Mar;92(2):371-85, ix. Review. PubMed PMID: 18298984.


Liddle FJ, Frank DA. STAT1 expression is not required for polyp formation in Min mice. Mol Carcinog. 2008 Feb;47(2):75-9. PMID: 17683066


Song JW, Misgeld T, Kang H, Knecht S, Lu J, Cao Y, Cotman SL, Bishop DL, Lichtman JW. Lysosomal activity associated with developmental axon pruning. J Neurosci. 2008 Sep 3;28(36):8993-9001. PubMed PMID: 18768693; PubMed Central PMCID: PMC2693713.


Zhang Y, Zhou X, Lu J, Lichtman J, Adjeroh D, Wong ST. 3D Axon structure extraction and analysis in confocal fluorescence microscopy images. Neural Comput. 2008 Aug;20(8):1899-927. PubMed PMID: 18336075; PubMed Central PMCID: PMC2587013.


Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol. 2008 Jun 15;180(12):8004-10. PubMed PMID: 18523263.


Lin Y, Bloodgood BL, Hauser JL, Lapan AD, Koon AC, Kim TK, Hu LS, Malik AN, Greenberg ME. Activity-dependent regulation of inhibitory synapse development by Npas4. Nature. 2008 Oct 30; 455(7217):1198-204. PMCID: PMC2637532.


Denoux C, Galletti R, Mammarella N, Gopalan S, Werck D, De Lorenzo G, Ferrari S, Ausubel FM, Dewdney J. Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings. Mol Plant. 2008 May;1(3):423-45. Epub 2008 May 22. Review. Erratum in: Mol Plant. 2009 Jul;2(4):838. PubMed PMID: 19825551.


McEwen JM, Kaplan JM. UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin. Mol Biol Cell. 2008 Sep;19(9):3836-46. Epub 2008 Jul 2. PubMed PMID: 18596236; PubMed Central PMCID: PMC2526711.


Chun DK, McEwen JM, Burbea M, Kaplan JM. UNC-108/Rab2 regulates postendocytic trafficking in Caenorhabditis elegans. Mol Biol Cell. 2008 Jul;19(7):2682-95. Epub 2008 Apr 23. PubMed PMID: 18434599; PubMed Central PMCID: PMC2441656.


McKellar CE, Shatz CJ. Synaptogenesis in purified cortical subplate neurons.
Cereb Cortex. 2009 Aug;19(8):1723-37. Epub 2008 Nov 21. PubMed PMID: 19029062; PubMed Central PMCID: PMC2705692.


McLaughlin KA, Wucherpfennig KW. B cells and autoantibodies in the pathogenesis of multiple sclerosis and related inflammatory demyelinating diseases. Adv Immunol. 2008;98:121-49. Review. PMID: 18772005.


Verginis P, McLaughlin KA, Wucherpfennig KW, von Boehmer H, Apostolou I. Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3479-84. Epub 2008 Feb 25. PMID: 18299571. PMCID: PMC2265184.


Kawamura K, McLaughlin KA, Weissert R, Forsthuber TG. Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice. J Immunol. 2008 Sep 1;181(5):3202-11. PMID: 18713991. PMCID: PMC2724067.


Zhu BM, McLaughlin SK, Na R, Liu J, Cui Y, Martin C, Kimura A, Robinson GW, Andrews NC, Hennighausen L. Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression. Blood. 2008 Sep 1;112(5):2071-80. doi: 10.1182/blood-2007-12-127480. Epub 2008 Jun 13. PMID: 18552213 PMCID: PMC2518907 read article


Castang S, McManus HR, Turner KH, Dove SL. H-NS family members function coordinately in an opportunistic pathogen. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18947-52. doi: 10.1073/pnas.0808215105. Epub 2008 Nov 21. PMID: 19028873 PMCID: PMC2596223 read article


Mefford ME, Gorry PR, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues. AIDS Res Hum Retroviruses. 2008 Sep;24(9):1215-20. PMID: 18788913 PMCID: PMC2801411 read article


Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS One. 2008 Jun 25;3(6):e2516. PMID: 18575590 PMCID: PMC2424175 read article


Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, Walsh CA, Perrimon N.Identification of neural outgrowth genes using genome-wide RNAi. PLoS Genet. 2008 Jul 4;4(7):e1000111. PubMed PMID: 18604272; PubMed Central PMCID: PMC2435276.


Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. TIM-4 expressed on APCs induces T cell expansion and survival. J Immunol. 2008 Apr 1;180(7):4706-13. PubMed PMID: 18354194; PubMed Central PMCID: PMC2948965.


Sato-Jin K, Nishimura EK, Akasaka E, Huber W, Nakano H, Miller A, Du J, Wu M, Hanada K, Sawamura D, Fisher DE, Imokawa G. Epistatic connections between microphthalmia-associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders. FASEB J. 2008 Apr;22(4):1155-68. Epub 2007 Nov 26. PMID: 18039926


Bracken CM, Mizeracka K, McLaughlin KA. Patterning the embryonic kidney: BMP signaling mediates the differentiation of the pronephric tubules and duct in Xenopus laevis. Dev Dyn. 2008 Jan;237(1):132-44. PMID: 18069689


Love TM, Moffett HF, Novina CD. Not miR-ly small RNAs: big potential for microRNAs in therapy. J Allergy Clin Immunol. 2008 Feb;121(2):309-19. Review. PubMed PMID: 18269923.


Joshi PS, Molyneaux BJ, Feng L, Xie X, Macklis JD, Gan L. Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Neuron. 2008 Oct 23;60(2):258-72. PubMed PMID: 18957218; PubMed Central PMCID: PMC2643370.


Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD. SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Neuron. 2008 Jan 24;57(2):232-47. PubMed PMID: 18215621.


Arlotta P***, Molyneaux BJ***, Jabaudon D, Yoshida Y, Macklis JD. Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16;28(3):622-32. PubMed PMID: 18199763. ***Denotes equal contributions


Perlis RH, Moorjani P, Fagerness J, Purcell S, Trivedi MH, Fava M, Rush AJ, Smoller JW. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Neuropsychopharmacology. 2008 Nov;33(12):2810-9. Epub 2008 Feb 20. PubMed PMID: 18288090.


Agosto MA, Myers KS, Ivanovic T, Nibert ML. A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10571-6. doi: 10.1073/pnas.0802039105. Epub 2008 Jul 24. PMID: 18653761 PMCID: PMC2492467 read article


Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS. Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biol. 2008;9(7):R108. Epub 2008 Jul 8. PubMed PMID: 18611264; PubMed Central PMCID: PMC2530866.


Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, Heller EJ, Qi X, Lawton LN, Williams CJ, Georgopoulos K. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 2008 May 1;22(9):1174-89. PubMed PMID: 18451107; PubMed Central PMCID: PMC2335314.


Nguyen CL, Münger K. Direct association of the HPV16 E7 oncoprotein with cyclin A/CDK2 and cyclin E/CDK2 complexes. Virology. 2008 Oct 10;380(1):21-5. Epub 2008 Aug 21. PMID: 18718623PMCID: PMC2574417 read article


Nguyen CL, McLaughlin-Drubin ME, Münger K. Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Res. 2008 Nov 1;68(21):8715-22. PMID: 18974113 PMCID: PMC2597155 read article


Nguyen CL, Münger K. Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1. J Virol. 2009 Feb;83(4):1700-7. Epub 2008 Dec 3. PMID: 19052088 PMCID: PMC2643759 read article


Lan F, Nottke AC, Shi Y. Mechanisms involved in the regulation of histone lysine demethylases. Curr Opin Cell Biol. 2008 Jun;20(3):316-25. Epub 2008 Apr 25. Review. PubMed PMID: 18440794; PubMed Central PMCID: PMC2674377.


Olsen SR, Wilson RI. Cracking neural circuits in a tiny brain: new approaches for understanding the neural circuitry of Drosophila. Trends Neurosci. 2008 Oct;31(10):512-20. Epub 2008 Sep 3. Review. PubMed PMID: 18775572; PubMed Central PMCID: PMC2845908.


Olsen SR, Wilson RI. Lateral presynaptic inhibition mediates gain control in an olfactory circuit. Nature. 2008 Apr 24;452(7190):956-60. Epub 2008 Mar 16. PubMed PMID: 18344978; PubMed Central PMCID: PMC2824883.


Bassan M, Liu H, Madsen KL, Armsen W, Zhou J, Desilva T, Chen W, Paradise A, Brasch MA, Staudinger J, Gether U, Irwin N, Rosenberg PA. Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1. Eur J Neurosci. 2008 Jan;27(1):66-82. PubMed PMID: 18184314.


Westbrook TF, Hu G, Ang XL, Mulligan P, Pavlova NN, Liang A, Leng Y, Maehr R, Shi Y, Harper JW, Elledge SJ. SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature. 2008 Mar 20;452(7185):370-4. doi: 10.1038/nature06780. PMID: 18354483 PMCID: PMC2688689 read article


Piskounova E, Viswanathan SR, Janas M, LaPierre RJ, Daley GQ, Sliz P, Gregory RI. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem. 2008 Aug 1;283(31):21310-4. Epub 2008 Jun 12. PubMed PMID: 18550544.


Ponce CR, Lomber SG, Born RT. Integrating motion and depth via parallel pathways. Nat Neurosci. 2008 Feb;11(2):216-23. Epub 2008 Jan 13. PubMed PMID: 18193039; PubMed Central PMCID: PMC2377395.


Ponce CR, Born RT. Stereopsis. Curr Biol. 2008 Sep 23;18(18):R845-50. PubMed PMID: 18812074.


Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Exp Biol Med (Maywood). 2008 Feb;233(2):155-62. doi: 10.3181/0706-RM-167. PMID: 18222970


Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer. 2008 Nov 4;99(9):1375-9. doi: 10.1038/sj.bjc.6604662. Epub 2008 Sep 16. PMID: 18797460 PMCID: PMC2579683 read article


Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol. 2008 Dec;19(12):2282-7. doi: 10.1681/ASN.2008050513. Epub 2008 Nov 5. PMID: 18987304 PMCID: PMC2588112 read article


de la Iglesia N, Konopka G, Puram SV, Chan JA, Bachoo RM, You MJ, Levy DE, Depinho RA, Bonni A. Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev. 2008 Feb 15;22(4):449-62. doi: 10.1101/gad.1606508. Epub 2008 Feb 7. PMID: 18258752 PMCID: PMC2238667 read article


Raiser DM, Zacharek SJ, Roach RR, Curtis SJ, Sinkevicius KW, Gludish DW, Kim CF. Stem cell biology in the lung and lung cancers: using pulmonary context and classic approaches. Cold Spring Harb Symp Quant Biol. 2008;73:479-90. doi: 10.1101/sqb.2008.73.036. Epub 2008 Nov 21. PMID: 19028984


Ramdya P, Engert F. Emergence of binocular functional properties in a monocular neural circuit. Nat Neurosci. 2008 Sep;11(9):1083-90. PubMed PMID: 19160507; PubMed Central PMCID: PMC2958220.


Ramirez CL, Foley JE, Wright DA, Müller-Lerch F, Rahman SH, Cornu TI, Winfrey RJ, Sander JD, Fu F, Townsend JA, Cathomen T, Voytas DF, Joung JK. Unexpected failure rates for modular assembly of engineered zinc fingers. Nat Methods. 2008 May;5(5):374-5. Erratum in: Nat Methods. 2008 Jun;5(6):575. PubMed PMID: 18446154.


Mahrour N, Redwine WB, Florens L, Swanson SK, Martin-Brown S, Bradford WD, Staehling-Hampton K, Washburn MP, Conaway RC, Conaway JW. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. J Biol Chem. 2008 Mar 21;283(12):8005-13. doi: 10.1074/jbc.M706987200. Epub 2008 Jan 10. PMID: 18187417


Zhou B, von Gise A, Ma Q, Rivera-Feliciano J, Pu WT. Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium. Biochem Biophys Res Commun. 2008 Oct 24;375(3):450-3. doi: 10.1016/j.bbrc.2008.08.044. Epub 2008 Aug 21. PMID: 18722343 PMCID: PMC2610421 read article


Zhou B, Ma Q, Rajagopal S, Wu SM, Domian I, Rivera-Feliciano J, Jiang D, von Gise A, Ikeda S, Chien KR, Pu WT. Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature. 2008 Jul 3;454(7200):109-13. doi: 10.1038/nature07060. Epub 2008 Jun 22. PMID: 18568026 PMCID: PMC2574791 read article


Patel V, Booker M, Kramer M, Ross L, Celatka CA, Kennedy LM, Dvorin JD, Duraisingh MT, Sliz P, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. J Biol Chem. 2008 Dec 12;283(50):35078-85. doi: 10.1074/jbc.M804990200. Epub 2008 Oct 8. PMID: 18842591 PMCID: PMC2596402 read article


Runner VM, Podolny V, Buratowski S. The Rpb4 subunit of RNA polymerase II contributes to cotranscriptional recruitment of 3' processing factors. Mol Cell Biol. 2008 Mar;28(6):1883-91. doi: 10.1128/MCB.01714-07. Epub 2008 Jan 14. PMID: 18195044 PMCID: PMC2268395 read article


Safo P, Regehr WG. Timing dependence of the induction of cerebellar LTD. Neuropharmacology. 2008 Jan;54(1):213-8. Epub 2007 Jun 26. PubMed PMID: 17669443; PubMed Central PMCID: PMC2266067.


Shim SY, Samuels BA, Wang J, Neumayer G, Belzil C, Ayala R, Shi Y, Shi Y, Tsai LH, Nguyen MD. Ndel1 controls the dynein-mediated transport of vimentin during neurite outgrowth. J Biol Chem. 2008 May 2;283(18):12232-40. Epub 2008 Feb 26. PubMed PMID: 18303022.


Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ. Cancer proliferation gene discovery through functional genomics. Science. 2008 Feb 1;319(5863):620-4. Erratum in: Science.2008 Apr 18;320(5874):316. PubMed PMID: 18239126.


Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med. 2008 Aug;14(8):837-42. Epub 2008 Jun 22. PubMed PMID: 18568035; PubMed Central PMCID: PMC2772133.


Simon DJ, Madison JM, Conery AL, Thompson-Peer KL, Soskis M, Ruvkun GB, Kaplan JM, Kim JK. The microRNA miR-1 regulates a MEF-2-dependent retrograde signal at neuromuscular junctions. Cell. 2008 May 30;133(5):903-15. PubMed PMID: 18510933; PubMed Central PMCID: PMC2553566.


Bentley AM, Artavanis-Tsakonas S, Stanford JS. Nanocourses: a short course format as an educational tool in a biological sciences graduate curriculum. CBE Life Sci Educ. 2008 Summer;7(2):175-83. doi: 10.1187/cbe.07-07-0049. PMID: 18519608 PMCID: PMC2424306 read article


Langenau DM, Keefe MD, Storer NY, Jette CA, Smith AC, Ceol CJ, Bourque C, Look AT, Zon LI. Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 2008 Jul 10;27(30):4242-8. doi: 10.1038/onc.2008.56. Epub 2008 Mar 17. PMID: 18345029 PMCID: PMC2680704 read article


Sural TH, Peng S, Li B, Workman JL, Park PJ, Kuroda MI. The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome. Nat Struct Mol Biol. 2008 Dec;15(12):1318-25. Epub 2008 Nov 23. PubMed PMID: 19029895; PubMed Central PMCID: PMC2636508.


Swinburne IA, Miguez DG, Landgraf D, Silver PA. Intron length increases oscillatory periods of gene expression in animal cells. Genes Dev. 2008 Sep 1;22(17):2342-6. doi: 10.1101/gad.1696108. Epub 2008 Aug 14. PMID: 18703678 PMCID: PMC2532923 read article


Swinburne IA, Silver PA. Intron delays and transcriptional timing during development. Dev Cell. 2008 Mar;14(3):324-30. doi: 10.1016/j.devcel.2008.02.002. PMID: 18331713 PMCID: PMC2825037 read article


Cironi P, Swinburne IA, Silver PA. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. PMID: 18230610 PMCID: PMC2417160 read article


Ansel KM, Pastor WA, Rath N, Lapan AD, Glasmacher E, Wolf C, Smith LC, Papadopoulou N, Lamperti ED, Tahiliani M, Ellwart J, Shi YJ, Kremmer E, Rao A, Heissmeyer V. Mouse ERI-1 interacts with the ribosome and catalyzes 5.8S rRNA processing. Nature Structural Biology (2008) 15(5): 523-30. PMID: 18438418. PMCID: PMC3032500.


Tanner NA, Hamdan SM, Jergic S, Loscha KV, Schaeffer PM, Dixon NE, van Oijen AM. Single-molecule studies of fork dynamics in Escherichia coli DNA replication. Nat Struct Mol Biol. 2008 Feb;15(2):170-6. doi: 10.1038/nsmb.1381. Epub 2008 Jan 27. PMID: 18223657 PMCID: PMC2651573 read article


Campanella GS, Tager AM, El Khoury JK, Thomas SY, Abrazinski TA, Manice LA, Colvin RA, Luster AD. Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4814-9. doi: 10.1073/pnas.0801544105. Epub 2008 Mar 17. PMID: 18347328 PMCID: PMC2290783 read article


Medoff BD, Thomas SY, Luster AD. T cell trafficking in allergic asthma: the ins and outs. Annu Rev Immunol. 2008;26:205-32. doi: 10.1146/annurev.immunol.26.021607.090312. PMID: 18304002


Vashlishan AB, Madison JM, Dybbs M, Bai J, Sieburth D, Ch'ng Q, Tavazoie M, Kaplan JM. An RNAi screen identifies genes that regulate GABA synapses. Neuron. 2008 May 8;58(3):346-61. PubMed PMID: 18466746.


Venanzi ES, Melamed R, Mathis D, Benoist C. The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15860-5. Epub 2008 Oct 6. PubMed PMID: 18838677; PubMed Central PMCID: PMC2572942.


Villaseñor J, Besse W, Benoist C, Mathis D. Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15854-9. Epub 2008 Oct 3. PubMed PMID: 18836079; PubMed Central PMCID: PMC2572966.


Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Exp Biol Med (Maywood). 2008 Feb;233(2):155-62. doi: 10.3181/0706-RM-167. PMID: 18222970


Alekseyenko AA, Peng S, Larschan E, Gorchakov AA, Lee OK, Kharchenko P, McGrath SD, Wang CI, Mardis ER, Park PJ, Kuroda MI. A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome. Cell. 2008 Aug 22;134(4):599-609. PubMed PMID: 18724933; PubMed Central PMCID: PMC2613042.


Wein MN, Jones DC, Glimcher LH. Lentivirus delivery of shRNA constructs into osteoblasts.Methods Mol Biol. 2008;455:149-55. PMID: 18463817


Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE, Glimcher LH, Lian JB, Stein G, Anderson KC, Scadden DT. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice.J Clin Invest. 2008 Feb;118(2):491-504. PMID: 18219387 PMCID: PMC2213372


Werneck MB, Lugo-Villarino G, Hwang ES, Cantor H, Glimcher LH. T-bet plays a key role in NK-mediated control of melanoma metastatic disease. J Immunol. 2008 Jun 15;180(12):8004-10. PubMed PMID: 18523263.


Lu L, Kim HJ, Werneck MB, Cantor H. Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19420-5. Epub 2008 Dec 1. PubMed PMID: 19047627; PubMed Central PMCID: PMC2614776.


Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI; Tübingen 2000 Screen Consortium. montalcino, A zebrafish model for variegate porphyria. Exp Hematol. 2008 Sep;36(9):1132-42. doi: 10.1016/j.exphem.2008.04.008. Epub 2008 Jun 11. PMID: 18550261 PMCID: PMC2630115 read article


Han S, Witt RM, Santos TM, Polizzano C, Sabatini BL, Ramesh V. Pam (Protein associated with Myc) functions as an E3 ubiquitin ligase and regulates TSC/mTOR signaling. Cell Signal. 2008 Jun;20(6):1084-91. Epub 2008 Feb 1. PMID: 18308511. PubMed Central PMCID: PMC2435383.


Woodworth JS, Fortune SM, Behar SM. Bacterial protein secretion is required for priming of CD8+ T cells specific for the Mycobacterium tuberculosis antigen CFP10. Infect Immun. 2008 Sep;76(9):4199-205. Epub 2008 Jun 30. PubMed PMID: 18591224; PubMed Central PMCID: PMC2519428.


Wu Y, Woodworth JS, Shin DS, Morris S, Behar SM. Vaccine-elicited 10-kilodalton culture filtrate protein-specific CD8+ T cells are sufficient to mediate protection against Mycobacterium tuberculosis infection. Infect Immun. 2008 May;76(5):2249-55. Epub 2008 Mar 10. PubMed PMID: 18332205; PubMed Central PMCID: PMC2346695.


Woodworth JS, Wu Y, Behar SM. Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo. J Immunol. 2008 Dec 15;181(12):8595-603. PubMed PMID: 19050279; PubMed Central PMCID: PMC3133658.


Choi MY, Romer AI, Wang Y, Wu MP, Ito S, Leiter AB, Shivdasani RA. Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum. Mol Cell Biol. 2008 May;28(10):3208-18. doi: 10.1128/MCB.01737-07. Epub 2008 Mar 17. PMID: 18347062 PMCID: PMC2423174 read article


Wang B, Yanez A, Novina CD. MicroRNA-repressed mRNAs contain 40S but not 60S components. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5343-8. doi: 10.1073/pnas.0801102105. Epub 2008 Apr 4. PMID: 18390669 PMCID: PMC2291078 read article


Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz HR, Schier AF, Dulac C. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55. PubMed PMID: 18184563; PubMed Central PMCID: PMC2204047.


top

2007


Abraira VE, Hyun N, Tucker AF, Coling DE, Brown MC, Lu C, Hoffman GR, Goodrich LV. Changes in Sef levels influence auditory brainstem development and function. J Neurosci. 2007 Apr 18;27(16):4273-82. PubMed PMID: 17442811.


Agosto MA, Middleton JK, Freimont EC, Yin J, Nibert ML. Thermolabilizing pseudoreversions in reovirus outer-capsid protein micro 1 rescue the entry defect conferred by a thermostabilizing mutation. J Virol. 2007 Jul;81(14):7400-9. Epub 2007 May 16. PMID: 17507494 PMCID: PMC1933377 read article


Ivanovic T, Agosto MA, Chandran K, Nibert ML. A role for molecular chaperone Hsc70 in reovirus outer capsid disassembly. J Biol Chem. 2007 Apr 20;282(16):12210-9. Epub 2007 Feb 6. PMID: 17284448


Middleton JK, Agosto MA, Severson TF, Yin J, Nibert ML. Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles. Virology. 2007 May 10;361(2):412-25. Epub 2007 Jan 17. PMID: 17208266 PMCID: PMC1913285 read article


Koundakjian EJ, Appler JL, Goodrich LV. Auditory neurons make stereotypedwiring decisions before maturation of their targets. J Neurosci. 2007 Dec19;27(51):14078-88. PubMed PMID: 18094247.


Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 2007 Jul 11;26(13):3169-79. Epub 2007 Jun 21. PMID: 17581637 PMCID: PMC1914106 read article


Carvalho J, Arnold MM, Nibert ML. Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2. Virology. 2007 Aug 1;364(2):301-16. Epub 2007 Apr 23. PMID: 17451769 PMCID: PMC2486448 read article


Miller CL, Arnold MM, Broering TJ, Eichwald C, Kim J, Dinoso JB, Nibert ML. Virus-derived platforms for visualizing protein associations inside cells. Mol Cell Proteomics. 2007 Jun;6(6):1027-38. Epub 2007 Mar 5. PMID: 17339631


Wang JP, Asher DR, Chan M, Kurt-Jones EA, Finberg RW. Cutting Edge: Antibody-mediated TLR7-dependent recognition of viral RNA. Journal of Immunology (2007) 178: 3363-3367.


Asthana S, Roytberg M, Stamatoyannopoulos J, Sunyaev S. Analysis of sequence conservation at nucleotide resolution. PLoS Comput Biol. 2007 Dec;3(12):e254. doi: 10.1371/journal.pcbi.0030254. Epub 2007 Nov 14. PMID: 18166073 PMCID: PMC2230682 read article


Asthana S, Noble WS, Kryukov G, Grant CE, Sunyaev S, Stamatoyannopoulos JA. Widely distributed noncoding purifying selection in the human genome. Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12410-5. Epub 2007 Jul 17. PMID: 17640883 PMCID: PMC1941483 read article


Balibar CJ, Garneau-Tsodikova S, Walsh CT. Covalent CouN7 enzyme intermediate for acyl group shuttling in aminocoumarin biosynthesis. Chem Biol. 2007 Jun;14(6):679-90. PMID: 17584615


Fridman M, Balibar CJ, Lupoli T, Kahne D, Walsh CT, Garneau-Tsodikova S. Chemoenzymatic formation of novel aminocoumarin antibiotics by the enzymes CouN1 and CouN7. Biochemistry. 2007 Jul 17;46(28):8462-71. Epub 2007 Jun 20. PMID: 17580964


Balibar CJ, Howard-Jones AR, Walsh CT. Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation. Nat Chem Biol. 2007 Sep;3(9):584-92. Epub 2007 Aug 12. PMID: 17704773


Barker BR, Parvani JG, Meyer D, Hey AS, Skak K, Letvin NL. IL-21 Induces Apoptosis of Antigen-Specific CD8+ T Lymphocytes. Journal of Immunology, 2007; 179: 3596-3603.


Stokes MP, Rush J, Macneill J, Ren JM, Sprott K, Nardone J, Yang V, Beausoleil SA, Gygi SP, Livingstone M, Zhang H, Polakiewicz RD, Comb MJ. Profiling of UV-induced ATM/ATR signaling pathways. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19855-60. Epub 2007 Dec 6. PMID: 18077418 PMCID: PMC2148387 read article


Li X, Gerber SA, Rudner AD, Beausoleil SA, Haas W, Villén J, Elias JE, Gygi SP. Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae. J Proteome Res. 2007 Mar;6(3):1190-7. PMID: 17330950


Villén J, Beausoleil SA, Gerber SA, Gygi SP. Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1488-93. Epub 2007 Jan 22. PMID: 17242355 PMCID: PMC1785252 read article


Ma W, Berg J, Yellen G. Ketogenic diet metabolites reduce firing in central neurons by opening K(ATP) channels. J Neurosci. 2007 Apr 4;27(14):3618-25. PubMed PMID: 17409226.


Fu WY, Chen Y, Sahin M, Zhao XS, Shi L, Bikoff JB, Lai KO, Yung WH, Fu AK, Greenberg ME, Ip NY. Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism. Nat Neurosci. 2007 Jan;10(1):67-76. Epub 2006 Dec 3. PubMed PMID: 17143272.


Tolias KF, Bikoff JB, Kane CG, Tolias CS, Hu L, Greenberg ME. The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development. Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7265-70. Epub 2007 Apr 17. PubMed PMID: 17440041; PubMed Central PMCID: PMC1855368.


Shalizi A, Bilimoria PM, Stegmüller J, Gaudillière B, Yang Y, Shuai K, BonniA. PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendriticmorphogenesis. J Neurosci. 2007 Sep 12;27(37):10037-46. PubMed PMID: 17855618.


Bloodgood BL, Sabatini BL. Nonlinear regulation of unitary synaptic signals by CaV(2.3) voltage-sensitive calcium channels located in dendritic spines. Neuron. 2007 Jan 18;53(2):249-60. PubMed PMID: 17224406.


Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci. 2007 Mar 14;27(11):2866-75. PubMed PMID: 17360908.


Bloodgood BL, Sabatini BL. Ca(2+) signaling in dendritic spines. Curr Opin Neurobiol. 2007 Jun;17(3):345-51. Epub 2007 Apr 23. Review. PubMed PMID: 17451936.


Bloodgood BL, Sabatini BL. Regulation of synaptic signalling by postsynaptic, non-glutamate receptor ion channels. J Physiol. 2008 Mar 15;586(6):1475-80. Epub 2007 Dec 20. Review. PubMed PMID: 18096597; PubMed Central PMCID: PMC2375695.


Moran ST, Cariappa A, Liu H, Muir B, Sgroi D, Boboila C, Pillai S. Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes. J Immunol. 2007;179(1):195-200


Cariappa A, Boboila C, Moran ST, Liu H, Shi HN, Pillai S. The recirculating B cell pool contains two functionally distinct, long-lived, posttransitional, follicular B cell populations. J Immunol. 2007;179(4):2270-81


Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M, Gumaste S, Geyer M, Zarrin AA, Manis JP, Rajewsky K, Alt FW. IgH class switching and translocations use a robust non-classical end-joining pathway. Nature. 2007;449(7161):478-82.


Dauguet J, Bock D, Reid RC, Warfield SK. Alignment of large image series using cubic B-splines tessellation: application to transmission electron microscopy data. Med Image Comput Comput Assist Interv. 2007;10(Pt 2):710-7. PubMed PMID: 18044631.


Gauguet JM, Bonasio R and von Andrian UH. High endothelial venules. In: The Endothelium: A Comprehensive Reference. (2007) Aird WC (ed.). Cambridge University Press (ISBN 9780521853767), pp. 1568-1588.


Bonasio R, Carman CV, Kim E, Sage PT, Love KR, Mempel TR, Springer TA, von Andrian UH (2007). Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots. Proceedings of the National Academy of Sciences 104:14753-8. PMID: 17785425; PMCID: PMC1976196.


Hughes ME, Bortnick R, Tsubouchi A, Bäumer P, Kondo M, Uemura T, Schmucker D. Homophilic Dscam interactions control complex dendrite morphogenesis. Neuron. 2007 May 3;54(3):417-27. PubMed PMID: 17481395; PubMed Central PMCID: PMC1963440.


Boutwell CL, Essex M. Identification of HLA class I-associated amino acid polymorphisms in the HIV-1C proteome. AIDS Res Hum Retroviruses. 2007 Jan;23(1):165-74. PMID: 17263647


Yi CH, Sogah DK, Boyce M, Degterev A, Christofferson DE, Yuan J. A genome-wide RNAi screen reveals multiple regulators of caspase activation. J Cell Biol. 2007 Nov 19;179(4):619-26. Epub 2007 Nov 12. PMID: 17998402 PMCID: PMC2080898 read article


Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL. Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. J Biol Chem. 2007 Feb 9;282(6):3989-97. Epub 2006 Dec 8. PMID: 17158450


Kiel DP, Magaziner J, Zimmerman S, Ball L, Barton BA, Brown KM, Stone JP, Dewkett D, Birge SJ. Efficacy of a hip protector to prevent hip fracture in nursing home residents: the HIP PRO randomized controlled trial. JAMA. 2007 Jul 25;298(4):413-22. PubMed PMID: 17652295.


Xie Z, Moy LY, Sanada K, Zhou Y, Buchman JJ, Tsai LH. Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron. 2007 Oct 4;56(1):79-93. PubMed PMID: 17920017; PubMed Central PMCID: PMC2642594.


Buchman JJ, Tsai LH. Spindle regulation in neural precursors of flies andmammals. Nat Rev Neurosci. 2007 Feb;8(2):89-100. Epub 2007 Jan 17. Review. PubMed PMID: 17228329.


Colmenares SU, Buker SM, Buhler M, Dlakić M, Moazed D. Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi. Mol Cell. 2007 Aug 3;27(3):449-61. Epub 2007 Jul 19. PubMed PMID: 17658285.


Buker SM, Iida T, Bühler M, Villén J, Gygi SP, Nakayama J, Moazed D. Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast. Nat Struct Mol Biol. 2007 Mar;14(3):200-7. Epub 2007 Feb 25. PubMed PMID: 17310250.


Rodacki M, Svoren B, Butty V, Besse W, Laffel L, Benoist C, Mathis D. Altered natural killer cells in type 1 diabetic patients. Diabetes. 2007 Jan;56(1):177-85. PMID:17192480.


Butty V, Roy M, Sabeti P, Besse W, Benoist C, Mathis D. Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):570-5. Epub 2006 Dec 29. PMID:17197413.


Garibyan L, Lobito AA, Siegel RM, Call ME, Wucherpfennig KW, Geha RS. Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID). J Clin Invest. 2007 Jun;117(6):1550-7. Epub 2007 May 10. PubMed PMID: 17492055; PubMed Central PMCID: PMC1865037.


Call ME, Wucherpfennig KW. Common themes in the assembly and architecture of activating immune receptors. Nat Rev Immunol. 2007 Nov;7(11):841-50. Review. PubMed PMID: 17960150.


Crowley JJ, Carter AG, Regehr WG. Fast vesicle replenishment and rapid recovery from desensitization at a single synaptic release site. J Neurosci. 2007 May 16;27(20):5448-60. PubMed PMID: 17507567.


Carter AG, Soler-Llavina GJ, Sabatini BL. Timing and location of synaptic inputs determine modes of subthreshold integration in striatal medium spiny neurons. J Neurosci. 2007 Aug 15;27(33):8967-77. PubMed PMID: 17699678.


Catic A, Misaghi S, Korbel GA, Ploegh HL. ElaD, a deubiquitinating protease expressed by E. coli. PLoS ONE. 2007 Apr;2(4):e381.


Catic A, Sun ZY, Ratner D, Misaghi S, Galardy PG, Korbel GA, Spooner E, Samuelson J, Wagner G, Ploegh HL. Sequence and structure evolved separately in a ribosomal ubiquitin variant. EMBO J. 2007 Jul;26(14):3474-83.


Catic A, Fiebiger E, Korbel GA, Blom D, Galardy PJ, Ploegh HL. Screen for ISG15-crossreactive deubiquitinases. PLoS ONE. 2007 Jul;2(7):e679.


Love KR, Catic A, Schlieker C, Ploegh HL. Mechanism, biology and inhibitors of deubiquitinating enzymes. Nat. Chem. Biol. 2007 Nov;3(11):697-705. Review.


Chae TH, Walsh CA. Genes that control the size of the cerebral cortex. Novartis Found Symp. 2007;288:79-90; discussion 91-8. Review. PubMed PMID: 18494253.


Hett EC, Chao MC, Steyn AJ, Fortune SM, Deng LL, Rubin EJ. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol Microbiol. 2007 Nov;66(3):658-68. Epub 2007 Oct 4. PubMed PMID: 17919286.


Chen AC, Selkoe DJ. Response to: Pardossi-Piquard et al., "Presenilin-Dependent Transcriptional Control of the Abeta-Degrading Enzyme Neprilysin by Intracellular Domains of betaAPP and APLP." Neuron 46, 541-554. Neuron. 2007 Feb 15;53(4):479-83. PubMed PMID: 17296549.


Yang H, Baur JA, Chen A, Miller C, Adams JK, Kisielewski A, Howitz KT, Zipkin RE, Sinclair DA. Design and synthesis of compounds that extend yeast replicative lifespan. Aging Cell. 2007 Feb;6(1):35-43. Epub 2006 Dec 5. Erratum in: Aging Cell. 2007 Aug;6(4):593. Adams, Jeffrey K [added]; Kisielewski, Anne [added]; Howitz, Konrad T [added]; Zipkin, Robert E [added]. PubMed PMID: 17156081.


Zhou P, Porcionatto M, Pilapil M, Chen Y, Choi Y, Tolias KF, Bikoff JB, Hong
EJ, Greenberg ME, Segal RA. Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron. 2007 Jul 5;55(1):53-68. PubMed PMID: 17610817; PubMed Central PMCID: PMC2661852.


Christensen AP, Corey DP. TRP channels in mechanosensation: direct or indirect activation? Nat Rev Neurosci. 2007 Jul;8(7):510-21. Review. PubMed PMID: 17585304.


Yi CH, Sogah DK, Boyce M, Degterev A, Christofferson DE, Yuan J. A genome-wide RNAi screen reveals multiple regulators of caspase activation. J Cell Biol. 2007 Nov 19;179(4):619-26. Epub 2007 Nov 12. PMID: 17998402 PMCID: PMC2080898 read article


Pack-Chung E, Kurshan PT, Dickman DK, Schwarz TL. A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport. Nat Neurosci. 2007 Aug;10(8):980-9. Epub 2007 Jul 22. PubMed PMID: 17643120.


Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 2007 Dec 13;450(7172):1106-10. Epub 2007 Nov 21. PubMed PMID: 18033247; PubMed Central PMCID: PMC2988437.


Colmenares SU, Buker SM, Buhler M, Dlakić M, Moazed D. Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi. Mol Cell. 2007 Aug 3;27(3):449-61. Epub 2007 Jul 19. PubMed PMID: 17658285.


Gu TL, Mercher T, Tyner JW, Goss VL, Walters DK, Cornejo MG, Reeves C, Popova L, Lee K, Rush J, Daibata M, Miyoshi I, Gilliland DG, Druker BJ, Polakiewicz RD. A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia. Blood, 2007 Jul 1; 110 (1): 323-33.


Day CL, Kiepiela P, Leslie AJ, van der Stok M, Nair K, Ismail N, Honeyborne I, Crawford H, Coovadia HM, Goulder PJ, Walker BD, Klenerman P. Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection. J Virol. 2007 Jan;81(1):434-8. Epub 2006 Oct 18. PMID: 17050606 PMCID: PMC1797250 read article


Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y. The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell. 2007 Mar 23;128(6):1077-88. Epub 2007 Feb 22. PubMed PMID: 17320160.


Geffen MN, de Vries SE, Meister M. Retinal ganglion cells can rapidly change polarity from Off to On. PLoS Biol. 2007 Mar;5(3):e65. Erratum in: PLoS Biol. 2007 May;5(5):e136. PLoS Biol. 2007 Jul;5(7):e188. PubMed PMID: 17341132; PubMed Central PMCID: PMC1808116.


Deans MR, Antic D, Suyama K, Scott MP, Axelrod JD, Goodrich LV. Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear. J Neurosci. 2007 Mar 21;27(12):3139-47. PubMed PMID: 17376975


Djuretic IM, Levanon D, Negreanu V, Groner Y, Rao A, Ansel KM. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat Immunol. 2007 Feb;8(2):145-53. Epub 2006 Dec 31. PubMed PMID: 17195845.


Hu H, Djuretic I, Sundrud MS, Rao A. Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT. Trends Immunol. 2007 Aug;28(8):329-32. Epub 2007 Jul 6. PubMed PMID: 17618833.


Jinushi M, Nakazaki Y, Dougan M, Carrasco DR, Mihm M, Dranoff G. MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF. J Clin Invest. 2007 Jul;117(7):1902-13. PMID: 17557120 PMCID: PMC1884688


Enzler T, Gillessen S, Dougan M, Allison JP, Neuberg D, Oble DA, Mihm M, Dranoff G. Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of {beta}-cells. Blood. 2007 May 4; [Epub ahead of print] PMID: 17483299 PMCID: PMC1924767


Dougan SK, Rava P, Hussain MM, Blumberg RS. MTP regulated by an alternate promoter is essential for NKT cell development. J Exp Med. 2007 Mar 19;204(3):533-45. Epub 2007 Feb 20. PubMed PMID: 17312007; PubMed Central PMCID: PMC2137905.


Dougan SK, Kaser A, Blumberg RS. CD1 expression on antigen-presenting cells. Curr Top Microbiol Immunol. 2007;314:113-41. Review. PubMed PMID: 17593659. Zeissig S, Kaser A, Dougan SK, Nieuwenhuis EE, Blumberg RS. Role of NKT cells in the digestive system. III. Role of NKT cells in intestinal immunity. Am J Physiol Gastrointest Liver Physiol. 2007 Dec;293(6):G1101-5. Epub 2007 Aug 23. PubMed PMID: 17717040.


Zeissig S, Kaser A, Dougan SK, Nieuwenhuis EE, Blumberg RS. Role of NKT cells in the digestive system. III. Role of NKT cells in intestinal immunity. Am J Physiol Gastrointest Liver Physiol. 2007 Dec;293(6):G1101-5. Epub 2007 Aug 23. PubMed PMID: 17717040.


Newton IL, Woyke T, Auchtung TA, Dilly GF, Dutton RJ, Fisher MC, Fontanez KM, Lau E, Stewart FJ, Richardson PM, Barry KW, Saunders E, Detter JC, Wu D, Eisen JA, Cavanaugh CM. The Calyptogena magnifica chemoautotrophic symbiont genome.Science. 2007 Feb 16;315(5814):998-1000. PubMed PMID: 17303757.


Gates J, Mahaffey JP, Rogers SL, Emerson M, Rogers EM, Sottile SL, Van Vactor D, Gertler FB, Peifer M. Enabled plays key roles in embryonic epithelial morphogenesis in Drosophila. Development. 2007 Jun;134(11):2027-39. PubMed PMID: 17507404.


Saparov SM, Erlandson K, Cannon K, Schaletzky J, Schulman S, Rapoport TA, Pohl P. Determining the conductance of the SecY protein translocation channel for small molecules. Mol Cell. 2007 May 25;26(4):501-9. PMID: 17531809


Li W, Schulman S, Boyd D, Erlandson K, Beckwith J, Rapoport TA. The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Mol Cell. 2007 May 25;26(4):511-21. PMID: 17531810


Cohen DE, Davidow LS, Erwin JA, Xu N, Warshawsky D, Lee JT. The DXPas34 repeat regulates random and imprinted X inactivation. Dev Cell. 2007 Jan;12(1):57-71. PubMed PMID: 17199041.


Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D. Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking. J Biol Chem. 2007 Sep 28;282(39):28721-32. Epub 2007 Jul 18. PMID: 17636261


Everley PA, Gartner CA, Haas W, Saghatelian A, Elias JE, Cravatt BF, Zetter BR, Gygi SP. Assessing enzyme activities using stable isotope labeling and mass spectrometry. Mol Cell Proteomics. 2007 Oct;6(10):1771-7. Epub 2007 Jul 11. PMID: 17627935


Fredenburg RA, Rospigliosi C, Meray RK, Kessler JC, Lashuel HA, Eliezer D, Lansbury PT Jr. The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states. Biochemistry. 2007 Jun 19;46(24):7107-18. Epub 2007 May 26. PMID: 17530780


Dapprich J, Witter K, Gabel HW, Murphy NB, Albert ED. Identification of a new HLA-B allele (B*1576) by haplotype specific extraction. Hum Immunol. 2007 May;68(5):418-21. Epub 2007 Feb 15. PubMed PMID: 17462508; PubMed Central PMCID: PMC1945813.


Mougous JD, Gifford CA, Ramsdell TL, Mekalanos JJ. Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa. Nat Cell Biol. 2007 Jul;9(7):797-803. Epub 2007 Jun 10. PMID: 17558395


Giraud J, Haas M, Feener EP, Copps KD, Dong X, Dunn SL, White MF. Phosphorylation of Irs1 at SER-522 inhibits insulin signaling. Mol Endocrinol. 2007 Sep;21(9):2294-302. Epub 2007 Jun 19. PMID: 17579213


Goddard CA, Butts DA, Shatz CJ. Regulation of CNS synapses by neuronal MHC class I. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6828-33. Epub 2007 Apr 9. PubMed PMID: 17420446; PubMed Central PMCID: PMC1871870.


Zhang Z, Fan HY, Goldman JA, Kingston RE. Homology-driven chromatin remodeling by human RAD54. Nat Struct Mol Biol. 2007 May;14(5):397-405. Epub 2007 Apr 8. PubMed PMID: 17417655.


Gooley JJ, Saper CB. Is food-directed behavior an appropriate measure of circadian entrainment to restricted daytime feeding? J Biol Rhythms. 2007 Dec;22(6):479-83. PubMed PMID: 18057322.


Bhandawat V, Olsen SR, Gouwens NW, Schlief ML, Wilson RI. Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations. Nat Neurosci. 2007 Nov;10(11):1474-82. Epub 2007 Oct 7. PubMed PMID: 17922008; PubMed Central PMCID: PMC2838615.


Greenland JR, Letvin NL. Chemical adjuvants for plasmid DNA vaccines. Vaccine. 2007 May 10;25(19):3731-41. Epub 2007 Feb 20. Review. PMID: 17350735


Greenland JR, Geiben R, Ghosh S, Pastor WA, Letvin NL. Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis. J Immunol. 2007 May 1;178(9):5652-8. PMID: 17442948 PMCID: PMC2262927 read article


Qin L, Greenland JR, Moriya C, Cayabyab MJ, Letvin NL. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo. J Virol. 2007 Oct;81(19):10606-13. Epub 2007 Jul 25. PMID: 17652387 PMCID: PMC2045443 read article


Griffin RS, Costigan M, Brenner GJ, Ma CH, Scholz J, Moss A, Allchorne AJ, Stahl GL, Woolf CJ. Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity. J Neurosci. 2007 Aug 8;27(32):8699-708. PubMed PMID: 17687047.


Mills CD, Allchorne AJ, Griffin RS, Woolf CJ, Costigan M. GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord. Mol Cell Neurosci. 2007 Oct;36(2):185-94. Epub 2007 Jul 24. PubMed PMID: 17702601; PubMed Central PMCID: PMC2034440.


Kowal P, Gurtan AM, Stuckert P, D'Andrea AD, Ellenberger T. Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex. J Biol Chem. 2007 Jan 19;282(3):2047-55. Epub 2006 Nov 1. PMID: 17082180


Haushofer J, Kanwisher N. In the eye of the beholder: visual experience and categories in the human brain. Neuron. 2007 Mar 15;53(6):773-5. PubMed PMID: 17359912.


Mukherjee S, Robinson CA, Howe AG, Mazor T, Wood PA, Urgaonkar S, Hebert AM, Raychaudhuri D, Shaw JT. N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6651-5. Epub 2007 Sep 7. PMID: 17923406 PMCID: PMC3335298 read article


Hemming ML, Selkoe DJ, Farris W. Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease. Neurobiol Dis. 2007 Apr;26(1):273-81. Epub 2007 Jan 25. PubMed PMID: 17321748; PubMed Central PMCID: PMC2377010.


Hemming ML, Patterson M, Reske-Nielsen C, Lin L, Isacson O, Selkoe DJ. Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease. PLoS Med. 2007 Aug;4(8):e262. PubMed PMID: 17760499; PubMed Central PMCID: PMC1952204.


Henrickson SE, Hartmann EM, Ott G., Rosenwald A. Gene expression profiling in malignant lymphomas. Adv Exp Med Biol. 2007;593:134-46. Review. PMID: 17265723


Henrickson SE, von Andrian UH. Single-cell dynamics of T-cell priming. Curr Opin Immunol. 2007 Jun;19(3):249-58. Epub 2007 Apr 12. PMID: 17433876


Hauser AE, Junt T, Mempel TR, Sneddon MW, Kleinstein SH, Henrickson SE, von Andrian UH, Shlomchik MJ, Haberman AM. Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. Immunity. 2007 May;26(5):655-67. PMID: 17509908


Junt T, Moseman EA, Iannacone M, Massberg S, Lang PA, Boes M, Fink K, Henrickson SE, Shayakhmetov DM, Di Paolo NC, van Rooijen N, Mempel TR, Whelan SP, von Andrian UH. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature. 2007 Nov 1;450(7166):110-4. Epub 2007 Oct 14. PMID: 17934446


Zhou P, Porcionatto M, Pilapil M, Chen Y, Choi Y, Tolias KF, Bikoff JB, Hong EJ, Greenberg ME, Segal RA. Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron. 2007 Jul 5;55(1):53-68. PubMed PMID: 17610817; PubMed Central PMCID: PMC2661852.


Hooks BM, Chen C. Critical periods in the visual system: changing views for a model of experience-dependent plasticity. Neuron. 2007. 56: 312-326. PMID: 17964248.


Roy K, Murtie JC, El-Khodor BF, Edgar N, Sardi SP, Hooks BM, Benoit-Marand M, Chen C, Moore H, O'Donnell P, Brunner D, Corfas G. Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders. PNAS. 2007. 104: 8131-8136. PMCID: PMC1876583.


Hughes ME, Bortnick R, Tsubouchi A, Bäumer P, Kondo M, Uemura T, Schmucker D. Homophilic Dscam interactions control complex dendrite morphogenesis. Neuron. 2007 May 3;54(3):417-27. PubMed PMID: 17481395; PubMed Central PMCID: PMC1963440.


Ferkey DM, Hyde R, Haspel G, Dionne HM, Hess HA, Suzuki H, Schafer WR, Koelle MR, Hart AC. C. elegans G protein regulator RGS-3 controls sensitivity to sensory stimuli. Neuron. 2007 Jan 4;53(1):39-52. PubMed PMID: 17196529; PubMed Central PMCID: PMC1855255.


Tong W, Ibarra YM, Lodish HF. Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal. Exp Hematol. 2007 Sep;35(9):1447-55. Epub 2007 Jul 16. PubMed PMID: 17637498; PubMed Central PMCID: PMC2062518.


Jackson AC, Bean BP. State-dependent enhancement of subthreshold A-type potassium current by 4-aminopyridine in tuberomammillary nucleus neurons. J Neurosci. 2007 Oct 3;27(40):10785-96. PubMed PMID: 17913912.


Corbo JC, Myers CA, Lawrence KA, Jadhav AP, Cepko CL. A typology of photoreceptor gene expression patterns in the mouse. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12069-74. Epub 2007 Jul 9. PMID: 17620597 PMCID: PMC1913549 read article


Fredenburg RA, Rospigliosi C, Meray RK, Kessler JC, Lashuel HA, Eliezer D, Lansbury PT Jr. The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states. Biochemistry. 2007 Jun 19;46(24):7107-18. Epub 2007 May 26. PMID: 17530780


Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol. 2007 Feb;9(2):139-48. Epub 2006 Dec 24. PubMed PMID: 17187063.


Knoll AT, Meloni EG, Thomas JB, Carroll FI, Carlezon WA Jr. Anxiolytic-like effects of kappa-opioid receptor antagonists in models of unlearned and learned fear in rats. J Pharmacol Exp Ther. 2007 Dec;323(3):838-45. Epub 2007 Sep 6. PubMed PMID: 17823306.


Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27;317(5837):516-9. Epub 2007 Jun 21. PubMed PMID: 17588900.


Edry E, Koralov SB, Rajewsky K, Melamed D. Spontaneous Class Switch Recombination in B Cell Lymphopoiesis Generates Aberrant Switch Junctions and Is Increased after VDJ Rearrangement. J Immunol. 2007. Nov 15;179(10):6555-60.


Koundakjian EJ, Appler JL, Goodrich LV. Auditory neurons make stereotyped wiring decisions before maturation of their targets. J Neurosci. 2007 Dec 19;27(51):14078-88. PubMed PMID: 18094247.


Raft S, Koundakjian EJ, Quinones H, Jayasena CS, Goodrich LV, Johnson JE, Segil N, Groves AK. Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development. Development. 2007 Dec;134(24):4405-15. PubMed PMID: 18039969.


Kowalski MP, Dubouix-Bourandy A, Bajmoczi M, Golan DE, Zaidi T, Coutinho-Sledge YS, Gygi MP, Gygi SP, Wiemer EA, Pier GB. Host resistance to lung infection mediated by major vault protein in epithelial cells. Science. 2007 Jul 6;317(5834):130-2. PMID: 17615361 PMCID: PMC3685177 read article


Pack-Chung E, Kurshan PT, Dickman DK, Schwarz TL. A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport. Nat Neurosci. 2007 Aug;10(8):980-9. Epub 2007 Jul 22. PubMed PMID: 17643120.


Landis MW, Brown NE, Baker GL, Shifrin A, Das M, Geng Y, Sicinski P, Hinds PW. The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development. Cancer Res. 2007 Aug 15;67(16):7613-20. PMID: 17699765


Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH Jr, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol. 2008 Jan 15;313(2):584-93. Epub 2007 Nov 12. PubMed PMID: 18082680.


LeBleu VS, Macdonald B, Kalluri R. Structure and function of basement membranes. Exp Biol Med (Maywood). 2007 Oct;232(9):1121-9. Review. PubMed PMID: 17895520.


Sugimoto H, Yang C, LeBleu VS, Soubasakos MA, Giraldo M, Zeisberg M, Kalluri R. BMP-7 functions as a novel hormone to facilitate liver regeneration. FASEB J. 2007 Jan;21(1):256-64. Epub 2006 Nov 20. PubMed PMID: 17116741.


Salahuddin S, Lee Y, Vadnais M, Sachs BP, Karumanchi SA, Lim KH. Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy. Am J Obstet Gynecol. 2007 Jul;197(1):28.e1-6. PubMed PMID: 17618745.


Leibman M, Hochschild A. A sigma-core interaction of the RNA polymerase holoenzyme that enhances promoter escape. EMBO J. 2007 Mar 21;26(6):1579-90. Epub 2007 Mar 1. PMID: 17332752 PMCID: PMC1829379 read article


Sabeti PC1, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF, Lander ES; International HapMap Consortium, Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, Belmont JW, Boudreau A, Hardenbol P, Leal SM, Pasternak S, Wheeler DA, Willis TD, Yu F, Yang H, Zeng C, Gao Y, Hu H, Hu W, Li C, Lin W, Liu S, Pan H, Tang X, Wang J, Wang W, Yu J, Zhang B, Zhang Q, Zhao H, Zhao H, Zhou J, Gabriel SB, Barry R, Blumenstiel B, Camargo A, Defelice M, Faggart M, Goyette M, Gupta S, Moore J, Nguyen H, Onofrio RC, Parkin M, Roy J, Stahl E, Winchester E, Ziaugra L, Altshuler D, Shen Y, Yao Z, Huang W, Chu X, He Y, Jin L, Liu Y, Shen Y, Sun W, Wang H, Wang Y, Wang Y, Xiong X, Xu L, Waye MM, Tsui SK, Xue H, Wong JT, Galver LM, Fan JB, Gunderson K, Murray SS, Oliphant AR, Chee MS, Montpetit A, Chagnon F, Ferretti V, Leboeuf M, Olivier JF, Phillips MS, Roumy S, Sallée C, Verner A, Hudson TJ, Kwok PY, Cai D, Koboldt DC, Miller RD, Pawlikowska L, Taillon-Miller P, Xiao M, Tsui LC, Mak W, Song YQ, Tam PK, Nakamura Y, Kawaguchi T, Kitamoto T, Morizono T, Nagashima A, Ohnishi Y, Sekine A, Tanaka T, Tsunoda T, Deloukas P, Bird CP, Delgado M, Dermitzakis ET, Gwilliam R, Hunt S, Morrison J, Powell D, Stranger BE, Whittaker P, Bentley DR, Daly MJ, de Bakker PI, Barrett J, Chretien YR, Maller J, McCarroll S, Patterson N, Pe'er I, Price A, Purcell S, Richter DJ, Sabeti P, Saxena R, Schaffner SF, Sham PC, Varilly P, Altshuler D, Stein LD, Krishnan L, Smith AV, Tello-Ruiz MK, Thorisson GA, Chakravarti A, Chen PE, Cutler DJ, Kashuk CS, Lin S, Abecasis GR, Guan W, Li Y, Munro HM, Qin ZS, Thomas DJ, McVean G, Auton A, Bottolo L, Cardin N, Eyheramendy S, Freeman C, Marchini J, Myers S, Spencer C, Stephens M, Donnelly P, Cardon LR, Clarke G, Evans DM, Morris AP, Weir BS, Tsunoda T, Johnson TA, Mullikin JC, Sherry ST, Feolo M, Skol A, Zhang H, Zeng C, Zhao H, Matsuda I, Fukushima Y, Macer DR, Suda E, Rotimi CN, Adebamowo CA, Ajayi I, Aniagwu T, Marshall PA, Nkwodimmah C, Royal CD, Leppert MF, Dixon M, Peiffer A, Qiu R, Kent A, Kato K, Niikawa N, Adewole IF, Knoppers BM, Foster MW, Clayton EW, Watkin J, Gibbs RA, Belmont JW, Muzny D, Nazareth L, Sodergren E, Weinstock GM, Wheeler DA, Yakub I, Gabriel SB, Onofrio RC, Richter DJ, Ziaugra L, Birren BW, Daly MJ, Altshuler D, Wilson RK, Fulton LL, Rogers J, Burton J, Carter NP, Clee CM, Griffiths M, Jones MC, McLay K, Plumb RW, Ross MT, Sims SK, Willey DL, Chen Z, Han H, Kang L, Godbout M, Wallenburg JC, L'Archevêque P, Bellemare G, Saeki K, Wang H, An D, Fu H, Li Q, Wang Z, Wang R, Holden AL, Brooks LD, McEwen JE, Guyer MS, Wang VO, Peterson JL, Shi M, Spiegel J, Sung LM, Zacharia LF, Collins FS, Kennedy K, Jamieson R, Stewart J. Genome-wide detection and characterization of positive selection in human populations. Nature. 2007 Oct 18;449(7164):913-8. PMID: 17943131 PMCID: PMC2687721 read article


Kitamoto S, Sukhova GK, Sun J, Yang M, Libby P, Love V, Duramad P, Sun C, Zhang Y, Yang X, Peters C, Shi GP. Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice. Circulation. 2007 Apr 17;115(15):2065-75. Epub 2007 Apr 2. PubMed PMID: 17404153.


Love VA, Grabie N, Duramad P, Stavrakis G, Sharpe A, Lichtman A. CTLA-4 ablation and interleukin-12 driven differentiation synergistically augment cardiac pathogenicity of cytotoxic T lymphocytes. Circ Res. 2007 Aug 3;101(3):248-57. Epub 2007 Jun 14. PubMed PMID: 17569889.


Kim M, Hersh LB, Leissring MA, Ingelsson M, Matsui T, Farris W, Lu A, Hyman BT, Selkoe DJ, Bertram L, Tanzi RE. Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families. J Biol Chem. 2007 Mar 16;282(11):7825-32. Epub 2007 Jan 22. PubMed PMID: 17244626.


Lu J, Lichtman JW. Imaging the neuromuscular junction over the past centuries. Sheng Li Xue Bao. 2007 Dec 25;59(6):683-96. PubMed PMID: 18157463.


Livet J, Weissman TA, Kang H, Draft RW, Lu J, Bennis RA, Sanes JR, Lichtman JW. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature. 2007 Nov 1;450(7166):56-62. PubMed PMID: 17972876.


Srinivasan R, Zhou X, Miller E, Lu J, Lichtman J, Wong ST. Automated axon tracking of 3D confocal laser scanning microscopy images using guided probabilistic region merging. Neuroinformatics. 2007 Fall;5(3):189-203. Erratum in: Neuroinformatics. 2009 Spring;7(1):83. Litchman, Jeff [corrected to Lichtman, Jeff]. PubMed PMID: 17917130.


Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 2007 Oct 5;131(1):33-45. PubMed PMID: 17923086;PubMed Central PMCID: PMC2169385.


Sen P, Charini WA, Subbramanian RA, Manuel ER, Kuroda MJ, Autissier PA, Letvin NL. Clonal focusing of epitope-specific CD8+ T lymphocytes in rhesus monkeys following vaccination and simian-human immunodeficiency virus challenge. J Virol. 2008 Jan;82(2):805-16. Epub 2007 Oct 31. PMID: 17977967 PMCID: PMC2224610 read article


Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18993-8. Epub 2007 Nov 19. PubMed PMID: 18025461; PubMed Central PMCID: PMC2141896.


Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature. 2007 Dec 13;450(7172):1106-10. Epub 2007 Nov 21. PubMed PMID: 18033247; PubMed Central PMCID: PMC2988437.


McKee AE, Neretti N, Carvalho LE, Meyer CA, Fox EA, Brodsky AS, Silver PA. Exon expression profiling reveals stimulus-mediated exon use in neural cells. Genome Biol. 2007;8(8):R159. PMID: 17683528 PMCID: PMC2374990 read article


McKee AE, Silver PA. Systems perspectives on mRNA processing. Cell Res. 2007 Jul;17(7):581-90. PMID: 17621309


O'Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, Idrissova Z, Viglietta V, Rostasy K, Pohl D, Dale RC, Freedman M, Steinman L, Buckle GJ, Kuchroo VK, Hafler DA, Wucherpfennig KW. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nat Med. 2007 Feb;13(2):211-7. Epub 2007 Jan 12. PMID: 17237795.


Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, Clapham PR, Wolinsky SM, Crowe SM, Gabuzda D. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 2007 May 25;362(1):163-78. Epub 2007 Jan 18. PMID: 17239419 PMCID: PMC1973138 read article


Melroe GT, Silva L, Schaffer PA, Knipe DM. Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. Virology. 2007 Apr 10;360(2):305-21. Epub 2006 Nov 28. PMID: 17126870 PMCID: PMC1976290 read article


Crowson AN, Magro C, Miller A, Mihm MC Jr. The molecular basis of melanomagenesis and the metastatic phenotype. Semin Oncol. 2007 Dec;34(6):476-90. PMID: 18083371


Catic A, Misaghi S, Korbel GA, Ploegh HL. ElaD, a Deubiquitinating protease expressed by E. coli. PLoS One. 2007 Apr 18;2(4):e381. PMID: 17440617 PMCID: PMC1847702 read article


Catic A, Sun ZY, Ratner DM, Misaghi S, Spooner E, Samuelson J, Wagner G, Ploegh HL. Sequence and structure evolved separately in a ribosomal ubiquitin variant. EMBO J. 2007 Jul 25;26(14):3474-83. Epub 2007 Jun 28. PMID: 17599068 PMCID: PMC1933403 read article


Moerke NJ, Aktas H, Chen H, Cantel S, Reibarkh MY, Fahmy A, Gross JD, Degterev A, Yuan J, Chorev M, Halperin JA, Wagner G. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G. Cell. 2007 Jan 26;128(2):257-67. PMID: 17254965


Moffett HF, Novina CD. A small RNA makes a Bic difference. Genome Biol. 2007;8(7):221. Review. PubMed PMID: 17666120; PubMed Central PMCID: PMC2323214.


Molyneaux BJ, Arlotta P, Macklis JD. Molecular Development of Corticospinal Motor Neuron Circuitry. In: Cortical Development: Genes and Genetic Abnormalities, Novartis Foundation. 2007. 288:3-15.


Molyneaux, BJ***, Arlotta P***, Menezes J, Macklis JD. Neuronal Subtype Specification in the Cerebral Cortex. Nature Reviews Neuroscience. 2007. 8:427-437. ***Denotes equal contributions


Moran ST, Cariappa A, Liu H, Muir B, Sgroi D, Boboila C, Pillai S. Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes. J Immunol. 2007. Jul 1;179(1):195-200. PMID:17579038.


Cariappa A, Boboila C, Moran ST, Liu H, Shi HN, Pillai S. The recirculating B cell pool contains two functionally distinct, long-lived, posttransitional, follicular B cell populations. J Immunol. 2007. Aug 15;179(4):2270-81. PMID:17675488.


Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE. All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1219-23. Epub 2007 Jan 16. PubMed PMID: 17227845; PubMed Central PMCID: PMC1770895.


Massberg S, Schaerli P, Knezevic-Maramica I, Köllnberger M, Tubo N, Moseman EA, Huff IV, Junt T, Wagers AJ, Mazo IB, von Andrian UH. Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell. 2007 Nov 30;131(5):994-1008. PubMed PMID: 18045540; PubMed Central PMCID: PMC2330270


de Paz JL, Moseman EA, Noti C, Polito L, von Andrian UH, Seeberger PH. Profiling heparin-chemokine interactions using synthetic tools. ACS Chem Biol. 2007 Nov 20;2(11):735-44. PubMed PMID: 18030990; PubMed Central PMCID: PMC2716178


Junt T, Moseman EA, Iannacone M, Massberg S, Lang PA, Boes M, Fink K, Henrickson SE, Shayakhmetov DM, Di Paolo NC, van Rooijen N, Mempel TR, Whelan SP, von Andrian UH. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature. 2007 Nov 1;450(7166):110-4. Epub 2007 Oct 14. PubMed PMID: 17934446


Jayasekera JP, Moseman EA, Carroll MC. Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity. J Virol. 2007 Apr;81(7):3487-94. Epub 2007 Jan 3. PubMed PMID: 17202212; PubMed Central PMCID: PMC1866020


Neal J, Takahashi M, Silva M, Tiao G, Walsh CA, Sheen VL. Insights into thegyrification of developing ferret brain by magnetic resonance imaging. J Anat.2007 Jan;210(1):66-77. PubMed PMID: 17229284; PubMed Central PMCID: PMC2100265.


Nguyen CL, Eichwald C, Nibert ML, Münger K. Human papillomavirus type 16 E7 oncoprotein associates with the centrosomal component gamma-tubulin. J Virol. 2007 Dec;81(24):13533-43. Epub 2007 Oct 3. PMID: 17913829 PMCID: PMC2168839 read article


Bhandawat V, Olsen SR, Gouwens NW, Schlief ML, Wilson RI. Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations. Nat Neurosci. 2007 Nov;10(11):1474-82. Epub 2007 Oct 7. PubMed PMID: 17922008; PubMed Central PMCID: PMC2838615.


Olsen SR, Bhandawat V, Wilson RI. Excitatory interactions between olfactory processing channels in the Drosophila antennal lobe. Neuron. 2007 Apr 5;54(1):89-103. PubMed PMID: 17408580; PubMed Central PMCID: PMC2048819.


Olveczky BP, Baccus SA, Meister M. Retinal adaptation to object motion. Neuron. 2007 Nov 21;56(4):689-700. PubMed PMID: 18031685; PubMed Central PMCID: PMC2117331.


Rickmyre JL, Dasgupta S, Ooi DL, Keel J, Lee E, Kirschner MW, Waddell S, Lee LA. The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo. J Cell Sci. 2007 Oct 15;120(Pt 20):3565-77. Epub 2007 Sep 25. PMID: 17895362


Hovav AH, Panas MW, Osuna CE, Cayabyab MJ, Autissier P, Letvin NL. 2007. The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. J Virol. 2007 Dec;81(23):12793-802.


Pacholec M, Sello JK, Walsh CT, Thomas MG. Formation of an aminoacyl-S-enzyme intermediate is a key step in the biosynthesis of chloramphenicol. Org Biomol Chem. 2007 Jun 7;5(11):1692-4. Epub 2007 Apr 26. PMID: 17520135


Hovav AH, Panas MW, Osuna CE, Cayabyab MJ, Autissier P, Letvin NL.The impact of a boosting immunogen on the differentiation of secondary memory CD8+ T cells. J Virol. 2007 Dec;81(23):12793-802. Epub 2007 Sep 19. PMID:17881444. PMCID: PMC2169130.


Hovav AH, Panas MW, Rahman S, Sircar P, Gillard G, Cayabyab MJ, Letvin NL.Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. J Immunol. 2007 Nov 15;179(10):6725-33. PMID:17982062


Cinar B, Fang PK, Lutchman M, Di Vizio D, Adam RM, Pavlova N, Rubin MA, Yelick PC, Freeman MR. The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. EMBO J. 2007 Oct 31;26(21):4523-34. Epub 2007 Oct 11. PMID: 17932490 PMCID: PMC2063482 read article


Storch KF, Paz C, Signorovitch J, Raviola E, Pawlyk B, Li T, Weitz CJ. Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information. Cell. 2007 Aug 24;130(4):730-41. PMID: 17719549 PMCID: PMC2040024 read article


Storch KF, Paz C, Signorovitch J, Raviola E, Pawlyk B, Li T, Weitz CJ. Physiological importance of a circadian clock outside the suprachiasmatic nucleus. Cold Spring Harb Symp Quant Biol. 2007;72:307-18. doi: 10.1101/sqb.2007.72.053. PMID: 18419288


Pesola JM, Coen DM. In vivo fitness and virulence of a drug-resistant herpes simplex virus 1 mutant. J Gen Virol. 2007 May;88(Pt 5):1410-4. PMID: 17412967


Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EP, Landgraf D, Phillips I, Silver PA. Rational design of memory in eukaryotic cells. Genes Dev. 2007 Sep 15;21(18):2271-6.PMID: 17875664 PMCID: PMC1973140  read article


Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res. 2007 Nov 1;67(21):10123-8. PMID: 17974953


Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 2007 Jul;6(1):38-54. PMID: 17618855 PMCID: PMC2564846 read article


Rohas LM, St-Pierre J, Uldry M, Jäger S, Handschin C, Spiegelman BM. A fundamental system of cellular energy homeostasis regulated by PGC-1alpha. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7933-8. Epub 2007 Apr 30. PMID: 17470778 PMCID: PMC1876550 read article


Samuels BA, Hsueh YP, Shu T, Liang H, Tseng HC, Hong CJ, Su SC, Volker J, Neve RL, Yue DT, Tsai LH. Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron. 2007 Dec 6;56(5):823-37. PubMed PMID: 18054859; PubMed Central PMCID: PMC2151975.


Sauvageot CM, Kesari S, Stiles CD. Molecular pathogenesis of adult brain
tumors and the role of stem cells. Neurol Clin. 2007 Nov;25(4):891-924, vii.
Review. PubMed PMID: 17964020.


Saparov SM, Erlandson K, Cannon K, Schaletzky J, Schulman S, Rapoport TA, Pohl P. Determining the conductance of the SecY protein translocation channel for small molecules. Mol Cell. 2007 May 25;26(4):501-9. PMID: 17531809


Li W, Schulman S, Boyd D, Erlandson K, Beckwith J, Rapoport TA. The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Mol Cell. 2007 May 25;26(4):511-21. PMID: 17531810


Schwabish MA, Struhl K. The Swi/Snf complex is important for histone eviction during transcriptional activation and RNA polymerase II elongation in vivo. Mol Cell Biol. 2007 Oct;27(20):6987-95. Epub 2007 Aug 20. PMID: 17709398 PMCID: PMC2168902 read article


Li J, Brieher WM, Scimone ML, Kang SJ, Zhu H, Yin H, von Andrian UH, Mitchison T, Yuan J. Caspase-11 regulates cell migration by promoting Aip1 Cofilin-mediated actin depolymerization. Nat Cell Biol. 2007 Mar;9(3):276-86. Epub 2007 Feb 11. Erratum in: Nat Cell Biol. 2007 Apr;9(4):480. PubMed PMID: 17293856.


Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J Neurosci. 2007 Mar 14;27(11):2866-75. PubMed PMID: 17360908.


Gunasekera AM, Myrick A, Militello KT, Sims JS, Dong CK, Gierahn T, Le Roch K, Winzeler E, Wirth DF. Regulatory motifs uncovered among gene expression clusters in Plasmodium falciparum. Mol Biochem Parasitol. 2007 May;153(1):19-30. Epub 2007 Jan 18. PMID: 17307259


Deitsch K, Duraisingh M, Dzikowski R, Gunasekera A, Khan S, Le Roch K, Llinás M, Mair G, McGovern V, Roos D, Shock J, Sims J, Wiegand R, Winzeler E.


Hovav AH, Panas MW, Rahman S, Sircar P, Gillard G, Cayabyab MJ, Letvin NL. Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. J Immunol. 2007 Nov 15;179(10):6725-33. PMC2190620.


Smith JG, Cunningham JM. Receptor-induced thiolate couples Env activation to retrovirus fusion and infection. PLoS Pathog. 2007 Dec 21;3(12):e198. PubMed PMID: 18260686; PubMed Central PMCID: PMC2151085.


Yi CH, Sogah DK, Boyce M, Degterev A, Christofferson DE, Yuan J. A genome-wide RNAi screen reveals multiple regulators of caspase activation. J Cell Biol. 2007 Nov 19;179(4):619-26. Epub 2007 Nov 12. PMID: 17998402 PMCID: PMC2080898 read article


Carter AG, Soler-Llavina GJ, Sabatini BL. Timing and location of synaptic inputs determine modes of subthreshold integration in striatal medium spiny neurons. J Neurosci. 2007 Aug 15;27(33):8967-77. PubMed PMID: 17699678.


Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes Dev. 2007 Jun 1;21(11):1382-95. Epub 2007 May 17. PMID: 17510286 PMCID: PMC1877750 read article


Bihl F, Narayan M, Chisholm JV 3rd, Henry LM, Suscovich TJ, Brown EE, Welzel TM, Kaufmann DE, Zaman TM, Dollard S, Martin JN, Wang F, Scadden DT, Kaye KM, Brander C. Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes. J Virol. 2007 May;81(9):4904-8. Epub 2007 Feb 28. PMID: 17329344 PMCID: PMC1900166 read article


Tahiliani M, Mei P, Fang R, Leonor T, Rutenberg M, Shimizu F, Li J, Rao A, Shi Y. The Histone H3K4 Demethylase SMCX Links REST Target Genes to X-Linked Mental Retardation. Nature (2007) 447: 601-5. PMID: 17468742.


Hamdan SM, Johnson DE, Tanner NA, Lee JB, Qimron U, Tabor S, van Oijen AM, Richardson CC. Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement. Mol Cell. 2007 Aug 17;27(4):539-49. PMID: 17707227


Dodson AW, Taylor TJ, Knipe DM, Coen DM. Inhibitors of the sodium potassium ATPase that impair herpes simplex virus replication identified via a chemical screening approach. Virology. 2007 Sep 30;366(2):340-8. Epub 2007 Jun 1.PMID: 17544048 PMCID: PMC2099250 read article


Thomas SY, Banerji A, Medoff BD, Lilly CM, Luster AD. Multiple chemokine receptors, including CCR6 and CXCR3, regulate antigen-induced T cell homing to the human asthmatic airway. J Immunol. 2007 Aug 1;179(3):1901-12. PMID: 17641057


Bosley TM, Salih MA, Alorainy IA, Oystreck DT, Nester M, Abu Amero KK, Tischfield MA, Engle EC. Clinical characterization of the HOXA1 syndrome BSAS variant. Neurology. 2007 Sep 18;69(12):1245-53. PubMed PMID: 17875913; PubMed Central PMCID: PMC2826214.


Tse JC, Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J Cell Biochem. 2007 Jul 1;101(4):816-29. PMID: 17243120


Ulm JW, Perron M, Sodroski J, C Mulligan R. Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction. Virology. 2007 Jul 5;363(2):245-55. Epub 2007 Mar 6. PMID: 17343889


Venanzi ES, Gray DH, Benoist C, Mathis D. Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected. J Immunol. 2007 Nov 1;179(9):5693-700. PubMed PMID: 17947641.


Glimcher LH, Jones DC, Wein MN. Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3.Ann N Y Acad Sci. 2007 Nov;1116:174-81. Review. PMID: 18083927


Jones DC, Wein MN, Glimcher LH. Schnurri-3 is an essential regulator of osteoblast function and adult bone mass.Ann Rheum Dis. 2007 Nov;66 Suppl 3:iii49-51. Review. PMID: 17934096


Jones DC, Wein MN, Glimcher LH. Schnurri-3: a key regulator of postnatal skeletal remodeling. Adv Exp Med Biol. 2007;602:1-13. PMID: 17966382


Lu L, Ikizawa K, Hu D, Werneck MB, Wucherpfennig KW, Cantor H. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity. 2007 May;26(5):593-604. PubMed PMID: 17509909.


Kim DY, Carey BW, Wang H, Ingano LA, Binshtok AM, Wertz MH, Pettingell WH, He P, Lee VM, Woolf CJ, Kovacs DM. BACE1 regulates voltage-gated sodium channels and neuronal activity.Nat Cell Biol. 2007 Jul;9(7):755-64. Epub 2007 Jun 18. PMID: 17576410 PMCID: PMC2747787 read article


Moza B, Varma AK, Buonpane RA, Zhu P, Herfst CA, Nicholson MJ, Wilbuer AK, Seth NP, Wucherpfennig KW, McCormick JK, Kranz DM, Sundberg EJ. Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. EMBO J. 2007 Feb 21;26(4):1187-97. Epub 2007 Feb 1. PMID: 17268555 PMCID: PMC1852840


Cheng J, Zhou X, Miller E, Witt RM, Zhu J, Sabatini BL, Wong ST. A novel computational approach for automatic dendrite spines detection in two-photon laser scan microscopy. J Neurosci Methods. 2007 Sep 15;165(1):122-34. Epub 2007 May 24. PMID: 17629570. PubMed Central PMCID: PMC1989684.


Zhang Y, Zhou X, Witt RM, Sabatini BL, Adjeroh D, Wong ST. Dendritic spine detection using curvilinear structure detector and LDA classifier. Neuroimage. 2007 Jun;36(2):346-60. Epub 2007 Mar 13. PMID: 17448688.


Wong J, Obst R, Correia-Neves M, Losyev G, Mathis D, Benoist C. Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells. J Immunol. 2007 Jun 1;178(11):7032-41. PMID: 17513752.


Wong J, Mathis D, Benoist C. TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets. J Exp Med. 2007 Sep 3;204(9):2039-45. Epub 2007 Aug 27. PMID: 17724131.


Behar SM, Woodworth JS, Wu Y. Next generation: tuberculosis vaccines that elicit protective CD8+ T cells. Expert Rev Vaccines. 2007 Jun;6(3):441-56. Review. PubMed PMID: 17542758; PubMed Central PMCID: PMC3134449.


Yoon S, Molloy MJ, Wu MP, Cowan DB, Gussoni E. C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia. Dev Biol. 2007 Jan 1;301(1):70-81. Epub 2006 Nov 7. PMID: 17150207 PMCID: PMC1779902 read article


"Zhao WN, Malinin N, Yang FC, Staknis D, Gekakis N, Maier B, Reischl S, Kramer A, Weitz CJ. CIPC is a mammalian circadian clock protein without invertebrate homologues. Nat Cell Biol. 2007 Mar;9(3):268-75. Epub 2007 Feb 18. PubMed PMID: 17310242.
"


Shalizi A, Bilimoria PM, Stegmüller J, Gaudillière B, Yang Y, Shuai K, Bonni A. PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. J Neurosci. 2007 Sep 12;27(37):10037-46. PubMed PMID: 17855618.


top

2006


Agosto MA, Ivanovic T, Nibert ML. Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16496-501. Epub 2006 Oct 19. PMID: 17053074 PMCID: PMC1637610 read article


Pau AK, McLaughlin MM, Hu Z, Agyemang AF, Polis MA, Kottilil S. Predictors for Hematopoietic Growth Factors Use in HIV/HCV-Coinfected Patients Treated with Peginterferon Alfa 2b and Ribavirin. AIDS Patient Care STDS. 2006 Sep;20(9):612-9. PMID: 16987047


Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, Albacker LA, Koulmanda M, Freeman GJ, Sayegh MH, Sharpe AH. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med. 2006 Apr 17;203(4):883-95. Epub 2006 Apr 10. PMID: 16606670 PMCID: PMC2118286


Alvarez JV, Greulich H, Sellers WR, Meyerson M, Frank DA. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. Cancer Res. 2006 Mar 15;66(6):3162-8. PMID: 16540667


Liddle FJ, Alvarez JV, Poli V, Frank DA. Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants. Biochemistry. 2006 May 2;45(17):5599-605. PMID: 16634641


Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM. Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. J Biol Chem. 2006 Feb 24;281(8):5224-32. Epub 2005 Dec 20. PMID: 16371349


Balibar CJ, Walsh CT. GliP, a multimodular nonribosomal peptide synthetase in Aspergillus fumigatus, makes the diketopiperazine scaffold of gliotoxin. Biochemistry. 2006 Dec 19;45(50):15029-38. PMID: 17154540


Balibar CJ, Walsh CT. In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. Biochemistry. 2006 Dec 26;45(51):15444-57. Epub 2006 Dec 19. PMID: 17176066


Balsara ZR, Roan NR, Steele LN, Starnbach MN. Developmental regulation of Chlamydia trachomatis class I accessible protein-1, a CD8+ T cell antigen. J Infect Dis. 2006 May 15;193(10):1459-63. Epub 2006 Apr 12. PMID: 16619195.


Balsara ZR, Misaghi S, Lafave JN, Starnbach MN. Chlamydia trachomatis infection induces cleavage of the mitotic cyclin B1. Infect Immun. 2006 Oct;74(10):5602-8. PMC1594933.


Bernstein-Hanley I, Coers J, Balsara ZR, Taylor GA, Starnbach MN, Dietrich WF. The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14092-7. Epub 2006 Sep 7. PMC1599917.


Letvin NL, Mascola JR, Sun Y, Gorgone DA, Buzby AP, Xu L, Yang Z, Chakrabarti B, Rao SS, Schmitz JE, Montefiori DC, Barker BR, Bookstein FL, Nabel GJ. Preserved CD4+ Central Memory T Cells and Survival in Vaccinated SIV-Challenged Monkeys. Science, 2006; 312:1530-1533.


Sun Y, Schmitz JE, Buzby AP, Barker BR, Rao SS, Xu L, Yang Z, Mascola JR, Nabel GJ, Letvin NL. Virus-specific Cellular Immune Correlates of Survival in Vaccinated Monkeys After Simian Immunodeficiency Virus Challenge. Journal of Virology, 2006; 80(22):10950-6. PMCID: PMC1642180.


Yurkovic A, Wang O, Basu AC, Kravitz EA. Learning and memory associated with aggression in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17519-24. Epub 2006 Nov 6. PubMed PMID: 17088536; PubMed Central PMCID: PMC1634832.


Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat Biotechnol. 2006 Oct;24(10):1285-92. Epub 2006 Sep 10. PMID: 16964243


Everley PA, Bakalarski CE, Elias JE, Waghorne CG, Beausoleil SA, Gerber SA, Faherty BK, Zetter BR, Gygi SP. Enhanced analysis of metastatic prostate cancer using stable isotopes and high mass accuracy instrumentation. J Proteome Res. 2006 May;5(5):1224-31. PMID: 16674112


Haas W, Faherty BK, Gerber SA, Elias JE, Beausoleil SA, Bakalarski CE, Li X, Villén J, Gygi SP. Optimization and use of peptide mass measurement accuracy in shotgun proteomics. Mol Cell Proteomics. 2006 Jul;5(7):1326-37. Epub 2006 Apr 23. PMID: 16635985


Vig M***, Beck A***, Billingsley JM***, Lis A, Parvez S, Peinelt C, Koomoa DL, Soboloff J, Gill DL, Fleig A, Kinet JP, Penner R. 2006. CRACM1 multimers form the ion-selective pore of the CRAC channel. Curr Biol. 16(20):2073-9. PMID: 16978865.***Equal Contribution.


Moran ST, Cariappa A, Liu H, Boboila C, Shi HN, Holland PM, Peschon JJ, Pillai S. Protein kinase C-associated kinase is not required for the development of peripheral B lymphocyte populations. Mol Immunol. 2006;43(10):1694-9.


Bonasio R, von Andrian UH. (2006). Origin, destination and function of circulating dendritic cells. Current Opinions in Immunology 18:503-11. PMID: 16777395.


Bonasio R, Scimone ML, Schaerli P, Grabie N, Lichtman AH, von Andrian UH (2006). Clonal deletion of autoreactive thymocytes by circulating dendritic cells homing to the thymus. Nature Immunology 7:1092-100. PMID: 16951687.


Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell. 2006 Jul 28;126(2):375-87.PubMed PMID: 16873067.


Barrington RA, Borde M, Rao A, Carroll MC. Involvement of NFAT1 in B cell self-tolerance. J Immunol. 2006 Aug 1;177(3):1510-5. PubMed PMID: 16849457.


Hu H, Wang B, Borde M, Nardone J, Maika S, Allred L, Tucker PW, Rao A. Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006 Aug;7(8):819-26. Epub 2006 Jul 2. PubMed PMID: 16819554.


Boyce M, Yuan J. Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ. 2006 Mar;13(3):363-73. PMID: 16397583


Boyce M, Scott F, Guogas LM, Gehrke L. Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex. J Mol Recognit. 2006 Jan-Feb;19(1):68-78. PMID: 16312015


Tomczak MF, Gadjeva M, Wang YY, Brown K, Maroulakou I, Tsichlis PN, Erdman SE, Fox JG, Horwitz BH. Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus. J Immunol. 2006 Jan 15;176(2):1244-51. PubMed PMID: 16394015.


Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP. Studies on the mechanism of RNAi-dependent heterochromatin assembly. Cold Spring Harb Symp Quant Biol. 2006;71:461-71. Review. PubMed PMID: 17381328.


Yeh WW, Cale EM, Jaru-Ampornpan P, Lord CI, Peyerl FW, Letvin NL. Compensatory substitutions restore normal core assembly in simian immunodeficiency virus isolates with Gag epitope cytotoxic T-lymphocyte escape mutations. J Virol. 2006 Aug;80(16):8168-77. PMID: 16873273 PMCID: PMC1563819


Wang B, Love TM, Call ME, Doench JG, Novina CD. Recapitulation of short RNA-directed translational gene silencing in vitro. Mol Cell. 2006 May 19;22(4):553-60. PubMed PMID: 16713585.


Xu C, Call ME, Wucherpfennig KW. A membrane-proximal tetracysteine motif contributes to assembly of CD3deltaepsilon and CD3gammaepsilon dimers with the T cell receptor. J Biol Chem. 2006 Dec 1;281(48):36977-84. Epub 2006 Oct 5. PubMed PMID: 17023417.


Call ME, Schnell JR, Xu C, Lutz RA, Chou JJ, Wucherpfennig KW. The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor. Cell. 2006 Oct 20;127(2):355-68. PubMed PMID: 17055436.


Feng J, Call ME, Wucherpfennig KW. The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site. PLoS Biol. 2006 May;4(5):e142. Epub 2006 Apr 25. PubMed PMID: 16623599; PubMed Central PMCID: PMC1440944.


DiBacco A, Ouyang J, Lee HY, Catic A, Ploegh H, Gill G. The SUMO-specific protease SENP5 is required for cell division. Mol. Cell. Biol. 2006 Jun;26(12):4489-98.


Misaghi S, Balsara ZR, Catic A, Spooner E, Ploegh HL, Starnbach MN. Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection. Mol. Microbiol. 2006 Jul;61(1):142-150.


Artavanis-Tsakonas K, Misaghi S, Comeaux CA, Catic A, Spooner E, Duraisingh MT, Ploegh H. Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum. Mol. Microbiol. 2006 Sep;61(5):1187-95.


Ghosh S, Chackerian AA, Parker CM, Ballantyne CM, Behar SM. The LFA-1 adhesion molecule is required for protective immunity during pulmonary Mycobacterium tuberculosis infection. J Immunol. 2006 Apr 15;176(8):4914-22. PubMed PMID: 16585587.


Ma Y, Li J, Chiu I, Wang Y, Sloane JA, Lü J, Kosaras B, Sidman RL, Volpe JJ, Vartanian T. Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis. J Cell Biol. 2006 Oct 23;175(2):209-15. PMID: 17060494.


Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC. Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006 Jan 23;203(1):141-52. Epub 2006 Jan 3. PMID: 16390934.


Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, Woolf CJ, Corey DP. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron. 2006 Apr 20;50(2):277-89. PubMed PMID: 16630838.


Yoshida M, Kobayashi K, Kuo TT, Bry L, Glickman JN, Claypool SM, Kaser A, Nagaishi T, Higgins DE, Mizoguchi E, Wakatsuki Y, Roopenian DC, Mizoguchi A, Lencer WI, and Blumberg RS. 2006. Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. J. Clin. Invest. 2006 Aug;116(8): 2142-2151. PMCID: PMC1501111.


Yoshida M, Masuda A, Kuo TT, Kobayashi K, Claypool SM, Takagawa T, Kutsumi H, Azuma T, Lencer WI, Blumberg RS. IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunity. Springer Semin. Immunopathol. 2006 Dec; 28(4): 397-403. PMID: 17051393.


Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP. Studies on the mechanism of RNAi-dependent heterochromatin assembly. Cold Spring Harb Symp Quant Biol. 2006;71:461-71. Review. PubMed PMID: 17381328.


Zhao B, Maruo S, Cooper A, R Chase M, Johannsen E, Kieff E, Cahir-McFarland E. RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1900-5. Epub 2006 Jan 30. PMID: 16446431 PMCID: PMC1413661. read article


von Arnim CA, Spoelgen R, Peltan ID, Deng M, Courchesne S, Koker M, Matsui T, Kowa H, Lichtenthaler SF, Irizarry MC, Hyman BT. GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing. J Neurosci. 2006. Sep 27;26(39):9913-22. PubMed PMID: 17005855.


Leslie A, Price DA, Mkhize P, Bishop K, Rathod A, Day C, Crawford H, Honeyborne I, Asher TE, Luzzi G, Edwards A, Rousseau CM, Mullins JI, Tudor-Williams G, Novelli V, Brander C, Douek DC, Kiepiela P, Walker BD, Goulder PJ. Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. J Immunol. 2006 Oct 1;177(7):4699-708. PMID: 16982909


Wherry EJ, Day CL, Draenert R, Miller JD, Kiepiela P, Woodberry T, Brander C, Addo M, Klenerman P, Ahmed R, Walker BD. HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory. Virology. 2006 Sep 30;353(2):366-73. Epub 2006 Jul 24. PMID: 16860834


Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006 Sep 21;443(7109):350-4. Epub 2006 Aug 20. PMID: 16921384


Honeyborne I, Rathod A, Buchli R, Ramduth D, Moodley E, Rathnavalu P, Chetty S, Day C, Brander C, Hildebrand W, Walker BD, Kiepiela P, Goulder PJ. Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa. J Immunol. 2006 Apr 15;176(8):4699-705. PMID: 16585563


Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature. 2006 Jul 27;442(7101):471-4. Epub 2006 Jun 28. PubMed PMID: 16810178.


Dekker JP, Yellen G. Cooperative gating between single HCN pacemaker channels. J Gen Physiol. 2006 Nov;128(5):561-7. Epub 2006 Oct 16. PubMed PMID: 17043149; PubMed Central PMCID: PMC2151591.


Deuel TA, Liu JS, Corbo JC, Yoo SY, Rorke-Adams LB, Walsh CA. Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth. Neuron. 2006 Jan 5;49(1):41-53. PubMed PMID: 16387638.


Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol. 2006;24:607-56. Review. PubMed PMID: 16551261.


Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, Fisher DE. Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. Cancer Cell. 2006 Jun;9(6):473-84. PMID: 16766266


Cheng H, Dufu K, Lee CS, Hsu JL, Dias A, Reed R. Human mRNA export machinery recruited to the 5' end of mRNA. Cell. 2006 Dec 29;127(7):1389-400. PMID: 17190602


Das R, Dufu K, Romney B, Feldt M, Elenko M, Reed R. Functional coupling of RNAP II transcription to spliceosome assembly. Genes Dev. 2006 May 1;20(9):1100-9. PMID: 16651655 PMCID: PMC1472470 read article


Everley PA, Bakalarski CE, Elias JE, Waghorne CG, Beausoleil SA, Gerber SA, Faherty BK, Zetter BR, Gygi SP. Enhanced analysis of metastatic prostate cancer using stable isotopes and high mass accuracy instrumentation. J Proteome Res. 2006 May;5(5):1224-31. PMID: 16674112


Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science. 2006 Feb 17;311(5763):1008-12. PubMed PMID: 16484497.


Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ. A CD8/Lck transgene is able to drive thymocyte differentiation. J Immunol, 177(9): 6007-17. 2006.


Selenko P, Serber Z, Gadea B, Ruderman J, Wagner G. Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact oocytes. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11904-9. Epub 2006 Jul 27. PMID: 16873549 PMCID: PMC1523310 read article


Gadea BB, Ruderman JV. Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4493-8. Epub 2006 Mar 14. PMID: 16537398 PMCID: PMC1401233 read article


Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP. Studies on the mechanism of RNAi-dependent heterochromatin assembly. Cold Spring Harb Symp Quant Biol. 2006;71:461-71. Review. PubMed PMID: 17381328.


Glater EE, Megeath LJ, Stowers RS, Schwarz TL. Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol. 2006 May 22;173(4):545-57. PubMed PMID: 16717129; PubMed Central PMCID: PMC2063864.


Gooley JJ, Schomer A, Saper CB. The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nat Neurosci. 2006 Mar;9(3):398-407. Epub 2006 Feb 19. PubMed PMID: 16491082.


Lockley SW, Gooley JJ. Circadian photoreception: spotlight on the brain. Curr Biol. 2006 Sep 19;16(18):R795-7. PubMed PMID: 16979545.


Fuller PM, Gooley JJ, Saper CB. Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback. J Biol Rhythms. 2006 Dec;21(6):482-93. Review. PubMed PMID: 17107938.


Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lötsch J, Fillingim RB, Maixner W, Geisslinger G, Max MB, Woolf CJ. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006 Nov;12(11):1269-77. Epub 2006 Oct 22. PubMed PMID: 17057711.


Gurtan AM, Stuckert P, D'Andrea AD. The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly. J Biol Chem. 2006 Apr 21;281(16):10896-905. Epub 2006 Feb 10. PMID: 16474167


Gurtan AM, D'Andrea AD. Dedicated to the core: understanding the Fanconi anemia complex. DNA Repair (Amst). 2006 Sep 8;5(9-10):1119-25. Epub 2006 Jun 19. PMID: 16784902


Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD, Dutta A. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation.Mol Cell. 2006 Aug;23(4):589-96. PMID: 16916645


Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH. Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Dev Biol. 2006 Apr 1;292(1):152-64. Epub 2006 Feb 8. PubMed PMID: 16469306.


Harpavat S, Cepko CL. RCAS-RNAi: a loss-of-function method for the developing chick retina. BMC Dev Biol. 2006 Jan 22;6:2. PubMed PMID: 16426460; PubMed Central PMCID: PMC1402266.


Hartman KN, Pal SK, Burrone J, Murthy VN. Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nat Neurosci. 2006 May;9(5):642-9. Epub 2006 Apr 2. PubMed PMID: 16582905.


Hayes GD, Frand AR, Ruvkun G. The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25. Development. 2006 Dec;133(23):4631-41. Epub 2006 Oct 25. PMID: 17065234


Hayes GD, Ruvkun G. Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs. Cold Spring Harb Symp Quant Biol. 2006;71:21-7. PMID: 17381276


Zhou Z, Hong EJ, Cohen S, Zhao WN, Ho HY, Schmidt L, Chen WG, Lin Y, Savner E, Griffith EC, Hu L, Steen JA, Weitz CJ, Greenberg ME. Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron. 2006 Oct 19;52(2):255-69. PubMed PMID: 17046689.


Hooks BM, Chen C. Distinct Roles for Spontaneous and Visual Activity in Remodeling of the Retinogeniculate Synapse. Neuron. 2006. 52: 281-291. PMID: 17046691.


Stegmüller J, Konishi Y, Huynh MA, Yuan Z, Dibacco S, Bonni A. Cell-intrinsic regulation of axonal morphogenesis by the Cdh1-APC target SnoN. Neuron. 2006 May 4;50(3):389-400. PMID: 16675394


Carre-Pierrat M, Baillie D, Johnsen R, Hyde R, Hart A, Granger L, Ségalat L. Characterization of the Caenorhabditis elegans G protein-coupled serotonin receptors. Invert Neurosci. 2006 Dec;6(4):189-205. Epub 2006 Nov 3. PubMed PMID: 17082916.


Jadhav AP, Cho SH, Cepko CL. Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):18998-9003. Epub 2006 Dec 5. PMID: 17148603 PMCID: PMC1682012 read article


Jadhav AP, Mason HA, Cepko CL. Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development. 2006 Mar;133(5):913-23. Epub 2006 Feb 1. PMID: 16452096


James RG, Kamei CN, Wang Q, Jiang R, Schultheiss TM. Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells. Development. 2006 Aug;133(15):2995-3004. Epub 2006 Jun 21. PubMed PMID: 16790474.


Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 7;16(3):230-41. PubMed PMID: 16461276.


Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, Feany MB, Dolph PJ, Supattapone S. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Sträussler-Scheinker syndrome. J Neurosci. 2006 Nov 29;26(48):12408-14. PubMed PMID: 17135402.


Khurana V, Feany MB. Connecting cell-cycle activation to neurodegeneration in Drosophila. Biochim Biophys Acta. 2007 Apr;1772(4):446-56. Epub 2006 Oct 18. Review. PubMed PMID: 17141486; PubMed Central PMCID: PMC2562667.


Cho NH, Kingston D, Chang H, Kwon EK, Kim JM, Lee JH, Chu H, Choi MS, Kim IS, Jung JU. Association of herpesvirus saimiri tip with lipid raft is essential for downregulation of T-cell receptor and CD4 coreceptor. J Virol. 2006 Jan;80(1):108-18. PMID: 16352535 PMCID: PMC1317525 read article


Meloni EG, Gerety LP, Knoll AT, Cohen BM, Carlezon WA Jr. Behavioral and anatomical interactions between dopamine and corticotropin-releasing factor in the rat. J Neurosci. 2006 Apr 5;26(14):3855-63. PubMed PMID: 16597740.


Kontopoulos E, Parvin JD, Feany MB. Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum Mol Genet. 2006 Oct 15;15(20):3012-23. Epub 2006 Sep 7. PubMed PMID: 16959795.


Koralov SB, Novobrantseva TI, Königsmann J, Ehlich A, Rajewsky K. Antibody repertoires generated by VH replacement and direct VH to JH joining. Immunity. 2006 Jul;25(1):43-53.


Casola S, Cattoretti G, Uyttersprot N, Koralov SB, Seagal J, Hao Z, Waisman A, Egert A, Ghitza D, Rajewsky K. Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7396-401. Epub 2006 May 1.


Lee AM, Wu CT. Enhancer-promoter communication at the yellow gene of Drosophila melanogaster: diverse promoters participate in and regulate trans interactions. Genetics. 2006 Dec;174(4):1867-80. Epub 2006 Oct 22. PubMed PMID: 17057235; PubMed Central PMCID: PMC1698615.


Bateman JR, Lee AM, Wu CT. Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange. Genetics. 2006 Jun;173(2):769-77. Epub 2006 Mar 17. PubMed PMID: 16547094; PubMed Central PMCID: PMC1526508.


Johnson KG, Tenney AP, Ghose A, Duckworth AM, Higashi ME, Parfitt K, Marcu O, Heslip TR, Marsh JL, Schwarz TL, Flanagan JG, Van Vactor D. The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development. Neuron. 2006. 49, 517-531 . PMID: 16476662


Kraves S, Weitz CJ. A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity. Nat Neurosci. 2006 Feb;9(2):212-9. Epub 2006 Jan 22. PubMed PMID: 16429135.


LaBonte ML, McKay PF, Letvin NL. Evidence of NK cell dysfunction in SIV-infected rhesus monkeys: impairment of cytokine secretion and NKG2C/C2 expression. Eur J Immunol. 2006 Sep;36(9):2424-33. PMID: 16906533


Landis MW, Pawlyk BS, Li T, Sicinski P, Hinds PW. Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. Cancer Cell. 2006 Jan;9(1):13-22. PMID: 16413468


Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villén J, Becker EB, DiBacco S, de la
Iglesia N, Gygi S, Blackwell TK, Bonni A. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell. 2006 Jun 2;125(5):987-1001. PubMed PMID: 16751106.


Lehtinen MK, Bonni A. Modeling oxidative stress in the central nervous system. Curr Mol Med. 2006 Dec;6(8):871-81. Review. PubMed PMID: 17168738.


Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, Albacker LA, Koulmanda M, Freeman GJ, Sayegh MH, Sharpe AH. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med. 2006 Apr 17;203(4):883-95. Epub 2006 Apr 10. PubMed PMID: 16606670; PubMed Central PMCID: PMC2118286.


Liang SC, Greenwald RJ, Latchman YE, Rosas L, Satoskar A, Freeman GJ, Sharpe AH. PD-L1 and PD-L2 have distinct roles in regulating host immunity to cutaneous leishmaniasis. Eur J Immunol. 2006 Jan;36(1):58-64. PubMed PMID: 16358363.


Liddle FJ, Alvarez JV, Poli V, Frank DA. Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants. Biochemistry. 2006 May 2;45(17):5599-605. PMID: 16634641


Cai H, Xu X, Lu J, Lichtman JW, Yung SP, Wong ST. Repulsive force based snake model to segment and track neuronal axons in 3D microscopy image stacks. Neuroimage. 2006 Oct 1;32(4):1608-20. Epub 2006 Jul 24. PubMed PMID: 16861006.


Wang J, Fathman JW, Lugo-Villarino G, Scimone L, von Andrian U, Dorfman DM, Glimcher LH. Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest. 2006 Feb;116(2):414-21. Epub 2006 Jan 12. PubMed PMID: 16410834; PubMed Central PMCID: PMC1326147.


Rosas LE, Snider HM, Barbi J, Satoskar AA, Lugo-Villarino G, Keiser T, Papenfuss T, Durbin JE, Radzioch D, Glimcher LH, Satoskar AR. Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani. J Immunol. 2006 Jul 1;177(1):22-5. PubMed PMID: 16785492.


Maimon G, Assad JA. Parietal area 5 and the initiation of self-timed movements versus simple reactions. J Neurosci. 2006 Mar 1;26(9):2487-98. PubMed PMID: 16510727.


Malecki MJ, Sanchez-Irizarry C, Mitchell JL, Histen G, Xu ML, Aster JC, Blacklow SC. Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes. Mol Cell Biol. 2006 Jun;26(12):4642-51. PMID: 16738328 PMCID: PMC1489116 read article


Manuel ER, Charini WA, Sen P, Peyerl FW, Kuroda MJ, Schmitz JE, Autissier P, Sheeter DA, Torbett BE, Letvin NL. Contribution of T-cell receptor repertoire breadth to the dominance of epitope-specific CD8+ T-lymphocyte responses. J Virol. 2006 Dec;80(24):12032-40. Epub 2006 Oct 11. PMID: 17035327 PMCID: PMC1676269 read article


Scott MM, Marcus JN, Elmquist JK. Orexin neurons and the TASK of glucosensing. Neuron. 2006 Jun 1;50(5):665-7. Review. PubMed PMID: 16731504.


Borowski C, Martin C, Gounari F, Haughn L, Aifantis I, Grassi F, von Boehmer H. On the brink of becoming a T cell. Curr Opin Immunol. 2002 Apr;14(2):200 6. Review. PubMed PMID: 11869893.


McKee AE, Silver PA. Systems biology of gene regulation fulfills its promise. Genome Biol. 2006;7(5):316. Epub 2006 May 22. PMID: 16719937


Brigl M, van den Elzen P, Chen X, Meyers JH, Wu D, Wong CH, Reddington F, Illarianov PA, Besra GS, Brenner MB, Gumperz JE. Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors. J Immunol. 2006 Mar 15;176(6):3625-34. PubMed PMID: 16517731.


Kuchroo VK, Meyers JH, Umetsu DT, DeKruyff RH. TIM family of genes in immunity and tolerance. Adv Immunol. 2006;91:227-49. Review. PubMed PMID: 16938542.


Miller AJ, Mihm MC Jr. Melanoma. N Engl J Med. 2006 Jul 6;355(1):51-65. PMID: 16822996


Misaghi S, Korbel GA, Kessler B, Spooner E, Ploegh HL. z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress. Cell Death Differ. 2006 Jan;13(1):163-5. PMID: 16003388


Misaghi S, Balsara ZR, Catic A, Spooner E, Ploegh HL, Starnbach MN. Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection. Mol Microbiol. 2006 Jul;61(1):142-50. PMID: 16824101


Artavanis-Tsakonas K, Misaghi S, Comeaux CA, Catic A, Spooner E, Duraisingh MT, Ploegh HL. Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum. Mol Microbiol. 2006 Sep;61(5):1187-95. PMID: 16925553


Balsara ZR, Misaghi S, Lafave JN, Starnbach MN. Chlamydia trachomatis infection induces cleavage of the mitotic cyclin B1. Infect Immun. 2006 Oct;74(10):5602-8. PMID: 16988235 PMCID: PMC1594933 read article


von der Haar T, Oku Y, Ptushkina M, Moerke N, Wagner G, Gross JD, McCarthy JE. Folding transitions during assembly of the eukaryotic mRNA cap-binding complex. J Mol Biol. 2006 Mar 3;356(4):982-92. Epub 2005 Dec 27. PMID: 16405910


Norris PJ, Stone JD, Anikeeva N, Heitman JW, Wilson IC, Hirschkorn DF, Clark MJ, Moffett HF, Cameron TO, Sykulev Y, Stern LJ, Walker BD. Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope. Mol Immunol. 2006 Mar;43(9):1349-57. Epub 2005 Oct 7. PubMed PMID: 16216327; PubMed Central PMCID: PMC2561961.


Moran ST, Cariappa A, Liu H, Boboila C, Shi HN, Holland PM, Peschon JJ, Pillai S. Protein kinase C-associated kinase is not required for the development of peripheral B lymphocyte populations. Mol Immunol. 2006. Apr;43(10):1694-9. PMID:16256200.


Ramsey IS, Moran MM, Chong JA, Clapham DE. A voltage-gated proton-selective channel lacking the pore domain. Nature. 2006 Apr 27;440(7088):1213-6. Epub 2006 Mar 22. PubMed PMID: 16554753.


Sheen VL, Ferland RJ, Neal J, Harney M, Hill RS, Banham A, Brown P, Chenn A, Corbo J, Hecht J, Folkerth R, Walsh CA. Neocortical neuronal arrangement in Miller Dieker syndrome. Acta Neuropathol. 2006 May;111(5):489-96. Epub 2006 Feb 3. PubMed PMID: 16456669.


Tsao JW, Neal J, Apse K, Stephan MJ, Dobyns WB, Hill RS, Walsh CA, Sheen VL. Cerebellar ataxia with progressive improvement. Arch Neurol. 2006Apr;63(4):594-7. PubMed PMID: 16606775.


Sheen VL, Ferland RJ, Harney M, Hill RS, Neal J, Banham AH, Brown P, Chenn A, Corbo J, Hecht J, Folkerth R, Walsh CA. Impaired proliferation and migration in human Miller-Dieker neural precursors. Ann Neurol. 2006 Jul;60(1):137-44. PubMed PMID: 16642511.


Neal J, Apse K, Sahin M, Walsh CA, Sheen VL. Deletion of chromosome 1p36 is associated with periventricular nodular heterotopia. Am J Med Genet A. 2006 Aug 1;140(15):1692-5. PubMed PMID: 16835933.


Neal J, Raju GP, Bodell A, Apse K, Walsh CA, Sheen VL. Periventricularheterotopia with complete agenesis of the corpus callosum : a case report. JNeurol. 2006 Oct;253(10):1358-9. Epub 2006 Aug 11. PubMed PMID: 16906346.


Yoshida T, Ng SY, Zuniga-Pflucker JC, Georgopoulos K. Early hematopoietic lineage restrictions directed by Ikaros. Nat Immunol. 2006 Apr;7(4):382-91. Epub 2006 Mar 5. PubMed PMID: 16518393.


Schratt GM, Tuebing F, Nigh EA, Kane CG, Sabatini ME, Kiebler M, Greenberg ME. A brain-specific microRNA regulates dendritic spine development. Nature. 2006 Jan 19;439(7074):283-9. Erratum in: Nature. 2006 Jun 15;441(7095):902. PubMed PMID: 16421561.


Hovav AH, Cayabyab MJ, Panas MW, Santra S, Greenland J, Geiben R, Haynes BF, Jacobs WR Jr, Letvin NL.Rapid memory CD8+ T-lymphocyte induction through priming with recombinant Mycobacterium smegmatis. J Virol. 2007 Jan;81(1):74-83. Epub 2006 Oct 18. PMID:17050608. PMCID: PMC1797252.


Sardi SP, Murtie J, Koirala S, Patten BA, Corfas G. Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. Cell. 2006 Oct 6;127(1):185-97. PMID: 17018285


Patten BA, Sardi SP, Koirala S, Nakafuku M, Corfas G. Notch1 signaling regulates radial glia differentiation through multiple transcriptional mechanisms. J Neurosci. 2006 Mar 22;26(12):3102-8.PMID: 16554461.


Born RT, Pack CC, Ponce CR, Yi S. Temporal evolution of 2-dimensional direction signals used to guide eye movements. J Neurophysiol. 2006 Jan;95(1):284-300. PubMed PMID: 16339508.


Poulin DL, DeCaprio JA. Is there a role for SV40 in human cancer? J Clin Oncol. 2006 Sep 10;24(26):4356-65. PMID: 16963733


Poulin DL, DeCaprio JA. The carboxyl-terminal domain of large T antigen rescues SV40 host range activity in trans independent of acetylation. Virology. 2006 May 25;349(1):212-21. Epub 2006 Feb 28. PMID: 16510165


Ramdya P, Reiter B, Engert F. Reverse correlation of rapid calcium signals in the zebrafish optic tectum in vivo. J Neurosci Methods. 2006 Oct 30;157(2):230-7. Epub 2006 Jun 12. PubMed PMID: 16765450.


Rivera-Feliciano J, Lee KH, Kong SW, Rajagopal S, Ma Q, Springer Z, Izumo S, Tabin CJ, Pu WT. Development of heart valves requires Gata4 expression in endothelial-derived cells. Development. 2006 Sep;133(18):3607-18. Epub 2006 Aug 16. PMID: 16914500 PMCID: PMC2735081 read article


Rivera-Feliciano J, Tabin CJ*. Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field. Dev Biol. 2006 Jul 15;295(2):580-8. Epub 2006 Apr 4. PMID: 16730346 PMCID: PMC2680002 read article


Cooper MP, Qu L, Rohas LM, Lin J, Yang W, Erdjument-Bromage H, Tempst P, Spiegelman BM. Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex. Genes Dev. 2006 Nov 1;20(21):2996-3009. Epub 2006 Oct 18. PMID: 17050673 PMCID: PMC1620022 read article


Butty V, Roy M, Sabeti P, Besse W, Benoist C, Mathis D. Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):570-5. Epub 2006 Dec 29. PubMed PMID: 17197413; PubMed Central PMCID: PMC1766426.


Voynov V, Verstrepen KJ, Jansen A, Runner VM, Buratowski S, Fink GR. Genes with internal repeats require the THO complex for transcription. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14423-8. Epub 2006 Sep 18. PMID: 16983072 PMCID: PMC1599979 read article


Safo PK, Cravatt BF, Regehr WG. Retrograde endocannabinoid signaling in the cerebellar cortex. Cerebellum. 2006;5(2):134-45. Review. PubMed PMID: 16818388.


Xie Z, Samuels BA, Tsai LH. Cyclin-dependent kinase 5 permits efficient cytoskeletal remodeling--a hypothesis on neuronal migration. Cereb Cortex. 2006 Jul;16 Suppl 1:i64-8. Review. PubMed PMID: 16766709.


Sandoval GM, Duerr JS, Hodgkin J, Rand JB, Ruvkun G. A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans. Nat Neurosci. 2006 May;9(5):599-601. Epub 2006 Apr 9. PubMed PMID: 16604067.


Schwabish MA, Struhl K. Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II. Mol Cell. 2006 May 5;22(3):415-22. PMID: 16678113


Scimone ML, Aifantis I, Apostolou I, von Boehmer H, von Andrian UH. A multistep adhesion cascade for lymphoid progenitor cell homing to the thymus. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7006-11. Epub 2006 Apr 25. PubMed PMID: 16641096; PubMed Central PMCID: PMC1459009.


Bonasio R, Scimone ML, Schaerli P, Grabie N, Lichtman AH, von Andrian UH. Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus. Nat Immunol. 2006 Oct;7(10):1092-100. Epub 2006 Sep 3. Erratum in: Nat Immunol. 2006 Nov;7(11):1234. PubMed PMID: 16951687.


Townsend M, Shankar GM, Mehta T, Walsh DM, Selkoe DJ. Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers. J Physiol. 2006 Apr 15;572(Pt 2):477-92. Epub 2006 Feb 9. PubMed PMID: 16469784; PubMed Central PMCID: PMC1779683.


Soler-Llavina GJ, Sabatini BL. Synapse-specific plasticity and compartmentalized signaling in cerebellar stellate cells. Nat Neurosci. 2006 Jun;9(6):798-806. Epub 2006 May 7. PubMed PMID: 16680164.


Balsara ZR, Roan NR, Steele LN, Starnbach MN. Developmental regulation of Chlamydia trachomatis class I accessible protein-1, a CD8+ T cell antigen. J Infect Dis. 2006 May 15;193(10):1459-63. Epub 2006 Apr 12. PubMed PMID: 16619195.


Swinburne IA, Meyer CA, Liu XS, Silver PA, Brodsky AS. Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription. Genome Res. 2006 Jul;16(7):912-21. Epub 2006 Jun 12. PMID: 16769980 PMCID: PMC1484458 read article


Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW. H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Mol Cell. 2006 Jan 20;21(2):201-14. PubMed PMID: 16427010.


Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, Fox E, Bronson R, De Girolami U, Lee C, Alt FW. XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7378-83. Epub 2006 May 2. PubMed PMID: 16670198.


Khan IA, Thomas SY, Moretto MM, Lee FS, Islam SA, Combe C, Schwartzman JD, Luster AD. CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection. PLoS Pathog. 2006 Jun;2(6):e49. Epub 2006 Jun 9. PMID: 16789839 PMCID: PMC1475660  read article


Thomas SY, Lilly CM, Luster AD. Invariant natural killer T cells in bronchial asthma. N Engl J Med. 2006 Jun 15;354(24):2613-6; author reply 2613-6. PMID: 16775244


Mikhak Z, Fleming CM, Medoff BD, Thomas SY, Tager AM, Campanella GS, Luster AD. STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells. J Immunol. 2006 Apr 15;176(8):4959-67. PMID: 16585592


Islam SA, Thomas SY, Hess C, Medoff BD, Means TK, Brander C, Lilly CM, Tager AM, Luster AD. The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans. Blood. 2006 Jan 15;107(2):444-53. Epub 2005 Sep 22. PMID: 16179368 PMCID: PMC1490027  read article


Tischfield MA, Chan WM, Grunert JF, Andrews C, Engle EC. HOXA1 mutations are not a common cause of Duane anomaly. Am J Med Genet A. 2006 Apr 15;140(8):900-2. Review. PubMed PMID: 16528738; PubMed Central PMCID: PMC2553396.


Tsao DY, Freiwald WA, Tootell RB, Livingstone MS. A cortical region consisting entirely of face-selective cells. Science. 2006 Feb 3;311(5761):670-4. PubMed PMID: 16456083; PubMed Central PMCID: PMC2678572.


Tsao DY, Freiwald WA. What's so special about the average face? Trends Cogn Sci. 2006 Sep;10(9):391-3. Epub 2006 Aug 8. PubMed PMID: 16899396.


Jones DC*, Wein MN*, Oukka M, Hofstaetter J, Glimcher M, Glimcher LH. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science. 2006 May 26;312(5777):1223-7. PMID: 16728642


Lu L, Werneck MB, Cantor H. The immunoregulatory effects of Qa-1. Immunol Rev. 2006 Aug;212:51-9. Review. PubMed PMID: 16903905.


Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H. Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol. 2006 May;7(5):498-506. Epub 2006 Apr 9. PubMed PMID: 16604075.


Daniels R, Rusan NM, Wilbuer AK, Norkin LC, Wadsworth P, Hebert DN. Simian virus 40 late proteins possess lytic properties that render them capable of permeabilizing cellular membranes. J Virol. 2006 Jul;80(13):6575-87. PMID: 16775344 PMCID: PMC1488938


Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH. Mitoferrin is essential for erythroid iron assimilation. Nature. 2006 Mar 2;440(7080):96-100. PMID: 16511496


Kamath A, Woodworth JS, Behar SM. Antigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection. J Immunol. 2006 Nov 1;177(9):6361-9. PubMed PMID: 17056567; PubMed Central PMCID: PMC3133654.


Woodworth JS, Behar SM. Mycobacterium tuberculosis-specific CD8+ T cells and their role in immunity. Crit Rev Immunol. 2006;26(4):317-52. Review. PubMed PMID: 17073557; PubMed Central PMCID: PMC3134450.


Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villén J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell TK, Bonni A. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell. 2006 Jun 2;125(5):987-1001. PubMed PMID: 16751106.


Kaneko S, Wang J, Kaneko M, Yiu G, Hurrell JM, Chitnis T, Khoury SJ, He Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J Neurosci. 2006 Sep 20;26(38):9794-804. PMID: 16988050.


Yiu G, He Z. Glial Inhibition of CNS Axon Regeneration. Nat Rev Neurosci. 2006 Aug; 7(8):617-27. PMID: 16858390. PMCID: PMC2693386.


Zhang T, Sun Y, Tian E, Deng H, Zhang Y, Luo X, Cai Q, Wang H, Chai J, Zhang H. RNA-binding proteins SOP-2 and SOR-1 form a novel PcG-like complex in C.elegans. Development. 2006 Mar;133(6):1023-33.


top

2005


Nibert ML, Odegard AL, Agosto MA, Chandran K, Schiff LA. Putative autocleavage of reovirus mu1 protein in concert with outer-capsid disassembly and activation for membrane permeabilization. J Mol Biol. 2005 Jan 21;345(3):461-74. PMID: 15581891


Dougan SK, Salas A, Rava P, Agyemang A, Kaser A, Morrison J, Khurana A, Kronenberg M, Johnson C, Exley M, Hussain MM, Blumberg RS. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. J Exp Med. 2005 Aug 15;202(4):529-39. PMID: 16087713 PMCID: PMC2212858


Li Z, Burrone J, Tyler WJ, Hartman KN, Albeanu DF, Murthy VN. Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6131-6. Epub 2005 Apr 18. PubMed PMID: 15837917; PubMed Central PMCID: PMC1087931.


Alvarez JV, Febbo PG, Ramaswamy S, Loda M, Richardson A, Frank DA. Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors. Cancer Res. 2005 Jun 15;65(12):5054-62. PMID: 15958548


Greulich H, Chen TH, Feng W, Jänne PA, Alvarez JV, Zappaterra M, Bulmer SE, Frank DA, Hahn WC, Sellers WR, Meyerson M. Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants. PLoS Med. 2005 Nov;2(11):e313. Epub 2005 Oct 4. PMID: 16187797 PMCID: PMC1240052 read article


Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, Pan Y, Simon MC, Thompson CB, Gottlieb E. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell. 2005 Jan;7(1):77-85. PMID: 15652751


Broering TJ, Arnold MM, Miller CL, Hurt JA, Joyce PL, Nibert ML. Carboxyl-proximal regions of reovirus nonstructural protein muNS necessary and sufficient for forming factory-like inclusions. J Virol. 2005 May;79(10):6194-206. PMID: 15858004 PMCID: PMC1091696 read article


Repik A, Pincus SE, Ghiran I, Nicholson-Weller A, Asher DR, Cerny AM, Casey LS, Jones SM, Jones SN, Mohamed N, Klickstein LB, Spitalny G, Finberg RW. A transgenic mouse model for studying the clearance of blood-borne pathogens via human complement receptor 1 (CR1). Clin Exp Immunol. (2005) 140:230-40.


Asher DR, Cerny AM, Weiler SR, Horner JW, Keeler ML, Neptune MA, Jones SN, Bronson RT, Depinho RA, Finberg RW. Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development. Genesis (2005) 42:77-85.


Asher DR, Cerny AM, Finberg RW. The erythrocyte viral trap: transgenic expression of viral receptor on erythrocytes attenuates coxsackievirus B infection. Proc Natl Acad Sci U S A. (2005) 102:12897-902.


Asthana S, Schmidt S, Sunyaev S. A limited role for balancing selection. Trends Genet. 2005 Jan;21(1):30-2. PMID: 15680511


Balibar CJ, Vaillancourt FH, Walsh CT. Generation of D amino acid residues in assembly of arthrofactin by dual condensation/epimerization domains. Chem Biol. 2005 Nov;12(11):1189-200. PMID: 16298298


Hernáindez-Falcón J, Basu AC, Govindasamy S, Kravitz EA. Changes in heart rate associated with contest outcome in agonistic encounters in lobsters. Cell Mol Neurobiol. 2005 Mar;25(2):329-43. PubMed PMID: 16047545.


Dieguez-Acuna FJ, Gerber SA, Kodama S, Elias JE, Beausoleil SA, Faustman D, Gygi SP. Characterization of mouse spleen cells by subtractive proteomics. Mol Cell Proteomics. 2005 Oct;4(10):1459-70. Epub 2005 Jul 21. PMID: 16037072


Bianchetta MJ, Betensky RA, Cohen JB. Cell-surface MuSK self-association: a crucial role for the putative signal sequence. Biochemistry. 2005 Dec
13;44(49):16229-38. PubMed PMID: 16331983.


Tolias KF, Bikoff JB, Burette A, Paradis S, Harrar D, Tavazoie S, Weinberg RJ, Greenberg ME. The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines. Neuron. 2005 Feb 17;45(4):525-38. PubMed PMID: 15721239.


Kraft S, Fleming T, Billingsley JM, Lin SY, Jouvin MH, Storz P, Kinet JP. Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo. J Exp Med. 2005 Feb 7;201(3):385-96. Epub 2005 Jan 31. PubMed PMID: 15684326; PubMed Central PMCID: PMC2213034.


Ngo-Anh TJ, Bloodgood BL, Lin M, Sabatini BL, Maylie J, Adelman JP. SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines. Nat Neurosci. 2005 May;8(5):642-9. Epub 2005 Apr 24. PubMed PMID: 15852011.


Bloodgood BL, Sabatini BL. Neuronal activity regulates diffusion across the neck of dendritic spines. Science. 2005 Nov 4;310(5749):866-9. PubMed PMID: 16272125.


Gauguet JM, Bonasio R and von Andrian UH. High endothelial venules. In: Endothelial Cells in Health and Disease. (2005) Aird WC (ed.). Taylor & Francis, Boca Raton, FL. pp. 77-103.


Mazo IB, Honczarenko M, Leung H, Cavanagh LL, Bonasio R, Weninger W, Engelke K, Xia L, McEver RP, Koni PA, Silberstein LE, von Andrian UH (2005). Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells. Immunity 22:259-70. PMID: 15723813.


Halin C*, Scimone ML*, Bonasio R, Gauguet JM, Mempel TR, Quackenbush E, Proia RL, Mandala S, von Andrian UH (2005). The S1P-analog FTY720 differentially modulates T cell homing via HEV: T cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer's patches. Blood 106:1314-22. PMID: 15870184; PMCID: PMC1895188.


Cavanagh LL***, Bonasio R***, Mazo IB, Halin C, Cheng G, van der Velden AW, Cariappa A, Chase C, Russell P, Starnbach MN, Koni PA, Pillai S, Weninger W, von Andrian UH (2005). Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells. Nature Immunology 6:1029-37. PMID: 16155571; PMCID: PMC1780273.


Mandal M, Borowski C, Palomero T, Ferrando AA, Oberdoerffer P, Meng F, Ruiz-Vela A, Ciofani M, Zuniga-Pflucker JC, Screpanti I, Look AT, Korsmeyer SJ, Rajewsky K, von Boehmer H, Aifantis I. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J Exp Med. 2005 Feb 21;201(4):603-14.


Oberdoerffer P, Kanellopoulou C, Heissmeyer V, Paeper C, Borowski C, Aifantis I, Rao A, Rajewsky K. Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages. Mol Cell Biol. 2005 May;25(10):3896-905.


Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science. 2005 Feb 11;307(5711):935-9. PMID: 15705855


Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol. 2005 Jul;1(2):112-9. Epub 2005 May 29. PMID: 16408008


Ibrahim AS, Bowman JC, Avanessian V, Brown K, Spellberg B, Edwards JE Jr, Douglas CM. Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob Agents Chemother. 2005 Feb;49(2):721-7. PubMed PMID: 15673756; PubMed Central PMCID: PMC547300.


Call ME, Wucherpfennig KW. The T cell receptor: critical role of the membrane environment in receptor assembly and function. Annu Rev Immunol. 2005;23:101-25. Review. PubMed PMID: 15771567.


Feng J, Garrity D, Call ME, Moffett H, Wucherpfennig KW. Convergence on a distinctive assembly mechanism by unrelated families of activating immune receptors. Immunity. 2005 Apr;22(4):427-38. PubMed PMID: 15845448.


O'Connor KC, Appel H, Bregoli L, Call ME, Catz I, Chan JA, Moore NH, Warren KG, Wong SJ, Hafler DA, Wucherpfennig KW. Antibodies from inflamed central nervous system tissue recognize myelin oligodendrocyte glycoprotein. J Immunol. 2005 Aug 1;175(3):1974-82. PubMed PMID: 16034142.


Garrity D, Call ME, Feng J, Wucherpfennig KW. The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7641-6. Epub 2005 May 13. PubMed PMID: 15894612; PubMed Central PMCID: PMC1140444.


Catic A, Ploegh HL. Ubiquitin--conserved protein or selfish gene? Trends Biochem. Sci. 2005 Nov;30(11):600-4.


Ohki K, Chung S, Ch'ng YH, Kara P, Reid RC. Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex. Nature. 2005 Feb 10;433(7026):597-603. Epub 2005 Jan 19. PubMed PMID: 15660108.


Chan B, Greenan G, McKeon F, Ellenberger T. Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13075-80. Epub 2005 Aug 30. PMID: 16131541 PMCID: PMC1201586 read article


Choi Y, Borghesani PR, Chan JA, Segal RA. Migration from a mitogenic niche
promotes cell-cycle exit.
J Neurosci. 2005 Nov 9;25(45):10437-45. PubMed PMID: 16280582.


Saper CB, Lu J, Chou TC, Gooley J. The hypothalamic integrator for circadian rhythms. Trends Neurosci. 2005 Mar;28(3):152-7. Review. PubMed PMID: 15749169.


Clatworthy AE, Valencia-Burton MA, Haber JE, Oettinger MA. The MRE11-RAD50-XRS2 complex, in addition to other non-homologous end-joining factors, is required for V(D)J joining in yeast. J Biol Chem. 2005 May 27;280(21):20247-52. Epub 2005 Mar 9. PubMed PMID: 15757898.


Stirling CM, Charleston B, Takamatsu H, Claypool S, Lencer W, Blumberg RS, Wileman TE. Characterization of the porcine neonatal Fc receptor-potential use for trans-epithelial protein delivery. Immunology. 2005 Apr;114(4): 542-53. PMCID: PMC1782108.


Colodner KJ, Montana RA, Anthony DC, Folkerth RD, Girolami UD, Feany MB. Proliferative potential of human astrocytes. Journal of Neuropathology and Experimental Neurology, 2005 Feb 64(2): 163-9. PMID: 15751231.


Maruo S, Johannsen E, Illanes D, Cooper A, Zhao B, Kieff E. Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical. J Virol. 2005 Aug;79(16):10171-9. PMID: 16051810 PMCID: PMC1182629. read article


Hua F, Cornejo MG, Cardone MH, Stokes CL, Lauffenburger DA. Effects of Bcl-2 levels on Fas signaling-induced caspase-3 activation: molecular genetic tests of computational model prediction. Journal of Immunology, 2005 Jul 15;175 (2):985-95.


Currier SC, Lee CK, Chang BS, Bodell AL, Pai GS, Job L, Lagae LG, Al-Gazali LI, Eyaid WM, Enns G, Dobyns WB, Walsh CA. Mutations in POMT1 are found in a minority of patients with Walker-Warburg syndrome. Am J Med Genet A. 2005 Feb 15;133A(1):53-7. PubMed PMID: 15637732.


Ramduth D, Chetty P, Mngquandaniso NC, Nene N, Harlow JD, Honeyborne I, Ntumba N, Gappoo S, Henry C, Jeena P, Addo MM, Altfeld M, Brander C, Day C, Coovadia H, Kiepiela P, Goulder P, Walker B. Differential immunogenicity of HIV-1 clade C proteins in eliciting CD8+ and CD4+ cell responses. J Infect Dis. 2005 Nov 1;192(9):1588-96. Epub 2005 Sep 30 .PMID: 16206073


Lauer GM, Lucas M, Timm J, Ouchi K, Kim AY, Day CL, Schulze Zur Wiesch J, Paranhos-Baccala G, Sheridan I, Casson DR, Reiser M, Gandhi RT, Li B, Allen TM, Chung RT, Klenerman P, Walker BD. Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy. J Virol. 2005 Oct;79(20):12979-88. PMID: 16189000 PMCID: PMC1235828 read article


Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol. 2005 Sep 15;175(6):3603-13. PMID: 16148104


Kosaka T, Deans MR, Paul DL, Kosaka K. Neuronal gap junctions in the mouse main olfactory bulb: morphological analyses on transgenic mice. Neuroscience. 2005;134(3):757-69. PubMed PMID: 15979807.


Dietz SB, Murthy VN. Contrasting short-term plasticity at two sides of the
mitral-granule reciprocal synapse in the mammalian olfactory bulb. J Physiol.
2005 Dec 1;569(Pt 2):475-88. Epub 2005 Sep 15. PubMed PMID: 16166156; PubMed Central PMCID: PMC1464232.


Dougan SK, Salas A, Rava P, Agyemang A, Kaser A, Morrison J, Khurana A, Kronenberg M, Johnson C, Exley M, Hussain MM, Blumberg RS. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. J Exp Med. 2005 Aug 15;202(4):529-39. Epub 2005 Aug 8. PubMed PMID: 16087713; PubMed Central PMCID: PMC2212858.


Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature. 2005 Jul 7;436(7047):117-22. PMID: 16001072


Dudley DD, Chaudhuri J, Bassing CH, Alt FW. Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences. Adv Immunol. 2005;86:43-112. PMID: 15705419.


Benes CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP. The C2 domain of PKCdelta is a phosphotyrosine binding domain. Cell. 2005 Apr 22;121(2):271-80. PMID: 15851033


Everley PA, Zetter BR. Proteomics in tumor progression and metastasis. Ann N Y Acad Sci. 2005 Nov;1059:1-10. PMID: 16382037


Li J, Fontaine-Rodriguez EC, Whelan SP. Amino acid residues within conserved domain VI of the vesicular stomatitis virus large polymerase protein essential for mRNA cap methyltransferase activity. J Virol. 2005 Nov;79(21):13373-84. PMID: 16227259 PMCID: PMC1262600 read article


Foster KA, Crowley JJ, Regehr WG. The influence of multivesicular release and postsynaptic receptor saturation on transmission at granule cell to Purkinje cell synapses. J Neurosci. 2005 Dec 14;25(50):11655-65. PubMed PMID: 16354924.


Wang D, Kennedy S, Conte D Jr, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G. Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature. 2005 Jul 28;436(7050):593-7. PubMed PMID: 16049496.


Kim JK, Gabel HW, Kamath RS, Tewari M, Pasquinelli A, Rual JF, Kennedy S, Dybbs M, Bertin N, Kaplan JM, Vidal M, Ruvkun G. Functional genomic analysis of RNA interference in C. elegans. Science. 2005 May 20;308(5725):1164-7. Epub 2005 Mar 24. PubMed PMID: 15790806.


Gadea BB, Ruderman JV. Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts. Mol Biol Cell. 2005 Mar;16(3):1305-18. Epub 2004 Dec 22. PMID: 15616188 PMCID: PMC551494 read article


van den Elzen P, Garg S, Leon L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 6;437(7060):906-10. PMID:16208376


Hong EJ, Villén J, Gerace EL, Gygi SP, Moazed D. A cullin E3 ubiquitin ligase complex associates with Rik1 and the Clr4 histone H3-K9 methyltransferase and is required for RNAi-mediated heterochromatin formation. RNA Biol. 2005 Jul-Sep;2(3):106-11. Epub 2005 Jul 30. PubMed PMID: 17114925.


Greenland JR, Liu H, Berry D, Anderson DG, Kim WK, Irvine DJ, Langer R, Letvin NL. Beta-amino ester polymers facilitate in vivo DNA transfection and adjuvant plasmid DNA immunization. Mol Ther. 2005 Jul;12(1):164-70. PMID: 15963932


Gregory BD, Nickels BE, Darst SA, Hochschild A. An altered-specificity DNA-binding mutant of Escherichia coli sigma70 facilitates the analysis of sigma70 function in vivo. Mol Microbiol. 2005 Jun;56(5):1208-19. PMID: 15882415


Gregory BD, Deighan P, Hochschild A. An artificial activator that contacts a normally occluded surface of the RNA polymerase holoenzyme. J Mol Biol. 2005 Oct 28;353(3):497-506. Epub 2005 Sep 2. PMID: 16185714


Griffin RS. An Epac-dependent pain pathway. J Neurosci. 2005 Sep 7;25(36):8113-4. Review. PubMed PMID: 16148218.


Sen J, Harpavat S, Peters MA, Cepko CL. Retinoic acid regulates the expression of dorsoventral topographic guidance molecules in the chick retina. Development. 2005 Dec;132(23):5147-59. Epub 2005 Oct 26. PubMed PMID: 16251210.


Tolias KF, Bikoff JB, Burette A, Paradis S, Harrar D, Tavazoie S, Weinberg RJ, Greenberg ME. The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines. Neuron. 2005 Feb 17;45(4):525-38. PubMed PMID: 15721239.


Li Z, Burrone J, Tyler WJ, Hartman KN, Albeanu DF, Murthy VN. Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6131-6. Epub 2005 Apr 18. PubMed PMID: 15837917; PubMed Central PMCID: PMC1087931.


Hass MR, Yankner BA. A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein. J Biol Chem. 2005 Nov 4;280(44):36895-904. Epub 2005 Aug 15. PubMed PMID: 16103124; PubMed Central PMCID: PMC1562327.


Schiller PH, Haushofer J. What is the coordinate frame utilized for the generation of express saccades in monkeys? Exp Brain Res. 2005 Nov;167(2):178-86. Epub 2005 Nov 15. PubMed PMID: 16041513.


Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ. Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein. Biochemistry. 2005 May 3;44(17):6513-25. PubMed PMID: 15850385.


Hemming ML, Selkoe DJ. Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor. J Biol Chem. 2005 Nov 11;280(45):37644-50. Epub 2005 Sep 9. PubMed PMID: 16154999; PubMed Central PMCID: PMC2409196.


Thompson MA, Stumph J, Henrickson SE, Rosenwald A, Wang Q, Olson S, Brandt SJ, Roberts J, Zhang X, Shyr Y, Kinney MC. Differential gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas. Hum Pathol. 2005 May;36(5):494-504. PMID: 15948116


Hershberger KL, Kurian J, Korber BT, Letvin NL. Killer cell immunoglobulin-like receptors (KIR) of the African-origin sabaeus monkey: evidence for recombination events in the evolution of KIR. Eur J Immunol. 2005 Mar;35(3):922-35. PMID: 15714591


Hong EJ, West AE, Greenberg ME. Transcriptional control of cognitive development. Curr Opin Neurobiol. 2005 Feb;15(1):21-8. Review. PubMed PMID: 15721740.


Pack CC, Hunter JN, Born RT. Contrast dependence of suppressive influences in cortical area MT of alert macaque. J Neurophysiol. 2005 Mar;93(3):1809-15. Epub 2004 Oct 13. PubMed PMID: 15483068.


Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW. High fidelity TNA synthesis by Therminator polymerase. Nucleic Acids Res. 2005 Sep 12;33(16):5219-25. Print 2005. PubMed PMID: 16157867; PubMed Central PMCID: PMC1214552.


Ichida JK, Zou K, Horhota A, Yu B, McLaughlin LW, Szostak JW. An in vitro selection system for TNA. J Am Chem Soc. 2005 Mar 9;127(9):2802-3. PubMed PMID: 15740086.


Jackson SS, Ilyinskii P, Philippon V, Gritz L, Yafal AG, Zinnack K, Beaudry KR, Manson KH, Lifton MA, Kuroda MJ, Letvin NL, Mazzara GP, Panicali DL. Role of genes that modulate host immune responses in the immunogenicity and pathogenicity of vaccinia virus. J Virol. 2005 May;79(10):6554-9. PubMed PMID: 15858042; PubMed Central PMCID: PMC1091706.


Jackson SS, Schmitz JE, Kuroda MJ, McKay PF, Sumida SM, Martin KL, Yu F, Lifton MA, Gorgone DA, Letvin NL. Evaluation of CD62L expression as a marker for vaccine-elicited memory cytotoxic T lymphocytes. Immunology. 2005 Dec;116(4):443-53. PubMed PMID: 16313358; PubMed Central PMCID: PMC1802447.


Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM. Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16055-9. Epub 2005 Oct 24. PMID: 16247011 PMCID: PMC1266038 read article


Chong JA, Moran MM, Teichmann M, Kaczmarek JS, Roeder R, Clapham DE. TATA-binding protein (TBP)-like factor (TLF) is a functional regulator of transcription: reciprocal regulation of the neurofibromatosis type 1 and c-fos genes by TLF/TRF2 and TBP. Mol Cell Biol. 2005 Apr;25(7):2632-43. PubMed PMID: 15767669; PubMed Central PMCID: PMC1061635.


Sakata Y, Koibuchi N, Xiang F, Youngblood JM, Kamei CN, Chin MT. The spectrum of cardiovascular anomalies in CHF1/Hey2 deficient mice reveals roles in endocardial cushion, myocardial and vascular maturation. J Mol Cell Cardiol. 2006 Feb;40(2):267-73. Epub 2005 Oct 19. PubMed PMID: 16242143.


Field SJ, Madson N, Kerr ML, Galbraith KA, Kennedy CE, Tahiliani M, Wilkins A, Cantley LC. PtdIns(4,5)P2 functions at the cleavage furrow during cytokinesis. Curr Biol. 2005 Aug 9;15(15):1407-12. PMID: 16085494


Khurana V, Fulga TA, Feany MB. Senseless makes sense for spinocerebellar ataxia-1. Nat Neurosci. 2005 Nov;8(11):1422-4. PubMed PMID: 16251977.


Kimberly WT, Zheng JB, Town T, Flavell RA, Selkoe DJ. Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. J Neurosci. 2005 Jun 8;25(23):5533-43. PubMed PMID: 15944381.


Chang H, Gwack Y, Kingston D, Souvlis J, Liang X, Means RE, Cesarman E, Hutt-Fletcher L, Jung JU. Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA. J Virol. 2005 Apr;79(8):4651-63. PMID: 15795251 PMCID: PMC1069543 read article


Koprivica V, Cho KS, Park JB, Yiu G, Atwal J, Gore B, Kim JA, Lin E, Tessier-Lavigne M, Chen DF, He Z. EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science. 2005 Oct 7;310(5745):106-10. PubMed PMID: 16210539.


Koralov SB, Novobrantseva TI, Hochedlinger K, Jaenisch R, Rajewsky K. Direct in vivo VH to JH rearrangement violating the 12/23 rule. J Exp Med. 2005. 7;201(3):341-8. PMCID: PMC1237122.


Murthy M, Ranjan R, Denef N, Higashi ME, Schupbach T, Schwarz TL. Sec6 mutations and the Drosophila exocyst complex. J Cell Sci. 2005. 118, 1139-1150. PubMed PMID: 15728258.


Kramer A, Yang FC, Kraves S, Weitz CJ. A screen for secreted factors of the suprachiasmatic nucleus. Methods Enzymol. 2005;393:645-63. PubMed PMID: 15817317.


Baker GL, Landis MW, Hinds PW. Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation. Cell Cycle. 2005 Feb;4(2):330-8. Epub 2005 Feb 21. PMID: 15684604


Monticelli S, Ansel KM, Lee DU, Rao A. Regulation of gene expression in mast cells: micro-rNA expression and chromatin structural analysis of cytokine genes. Novartis Found Symp. 2005;271:179-87; discussion 187-90, 198-9. Review. PubMed PMID: 16605135.


Monticelli S, Lee DU, Nardone J, Bolton DL, Rao A. Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells. Int Immunol. 2005 Nov;17(11):1513-24. Epub 2005 Sep 30. PubMed PMID: 16199489.


Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A. The transcription factor NFAT3 mediates neuronal survival. J Biol Chem. 2005 Jan 28;280(4):2818-25. Epub 2004 Nov 10. PubMed PMID: 15537643.


van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 6;437(7060):906-10. PubMed PMID: 16208376.


Weingart SN, Pagovich O, Sands DZ, Li JM, Aronson MD, Davis RB, Phillips RS, Bates DW. Patient-reported service quality on a medicine unit. Int J Qual Health Care. 2006 Apr;18(2):95-101. Epub 2005 Nov 10. PubMed PMID: 16282334.


Weingart SN, Pagovich O, Sands DZ, Li JM, Aronson MD, Davis RB, Bates DW, Phillips RS. What can hospitalized patients tell us about adverse events? Learning from patient-reported incidents. J Gen Intern Med. 2005 Sep;20(9):830-6. PubMed PMID: 16117751; PubMed Central PMCID: PMC1490203.


Li JM, Li Y, Elledge SJ. Genetic analysis of the kinetochore DASH complex reveals an antagonistic relationship with the ras/protein kinase A pathway and a novel subunit required for Ask1 association. Mol Cell Biol. 2005 Jan;25(2):767-78. PubMed PMID: 15632076; PubMed Central PMCID: PMC543429.


Lugo-Villarino G, Ito S, Klinman DM, Glimcher LH. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13248-53. Epub 2005 Aug 31. PubMed PMID: 16135562; PubMed Central PMCID: PMC1201626.


Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK. Mice lacking ghrelin receptors resist the development of diet-induced obesity. J Clin Invest. 2005 Dec;115(12):3564-72. PubMed PMID: 16322794; PubMed Central PMCID: PMC1297251.


McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14. PMID: 16033648 PMCID: PMC1199591 read article


LaVail JH, Tauscher AN, Hicks JW, Harrabi O, Melroe GT, Knipe DM. Genetic and molecular in vivo analysis of herpes simplex virus assembly in murine visual system neurons. J Virol. 2005 Sep;79(17):11142-50. PMID: 16103165 PMCID: PMC1193612  read article


Meyers JH, Chakravarti S, Schlesinger D, Illes Z, Waldner H, Umetsu SE, Kenny J, Zheng XX, Umetsu DT, DeKruyff RH, Strom TB, Kuchroo VK. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation. Nat Immunol. 2005 May;6(5):455-64. Epub 2005 Mar 27. PubMed PMID: 15793576.


Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R,Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. J Immunol. 2005 Aug 1;175(3):1558-65. PubMed PMID: 16034094.


Meyers JH, Sabatos CA, Chakravarti S, Kuchroo VK. The TIM gene family regulates autoimmune and allergic diseases. Trends Mol Med. 2005 Aug;11(8):362-9. Review. PubMed PMID: 16002337.


Miller AJ, Levy C, Davis IJ, Razin E, Fisher DE. Sumoylation of MITF and its related family members TFE3 and TFEB. J Biol Chem. 2005 Jan 7;280(1):146-55. Epub 2004 Oct 25. PMID: 15507434


Misaghi S, Galardy PJ, Meester WJ, Ovaa H, Ploegh HL, Gaudet R. Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate. J Biol Chem. 2005 Jan 14;280(2):1512-20. Epub 2004 Nov 5. PMID: 15531586


Molyneaux BJ***, Arlotta P***, Hirata T, Hibi M, Macklis JD. Fezl Is Required for the Birth and Specification of Corticospinal Motor Neurons. Neuron. 2005. 47: 817-831. ***Denotes equal contributions.


Arlotta P***, Molyneaux BJ***, Chen J, Inoue J, Kominami R, Macklis JD. Neuronal Subtype Specific Genes that Control Corticospinal Motor Neuron Development in vivo. Neuron. 2005. 45: 207-21. (With preview and cover). ***Denotes equal contributions.


Pillai S, Cariappa A, Moran ST. Marginal zone B cells. Annu Rev Immunol. 2005. 23:161-96. PMID:15771569.


Chong JA, Moran MM, Teichmann M, Kaczmarek JS, Roeder R, Clapham DE. TATA-binding protein (TBP)-like factor (TLF) is a functional regulator of transcription: reciprocal regulation of the neurofibromatosis type 1 and c-fos genes by TLF/TRF2 and TBP. Mol Cell Biol. 2005 Apr;25(7):2632-43. PubMed PMID: 15767669; PubMed Central PMCID: PMC1061635.


Olveczky BP, Andalman AS, Fee MS. Vocal experimentation in the juvenile songbird requires a basal ganglia circuit. PLoS Biol. 2005 May;3(5):e153. Epub 2005 Mar 29. PubMed PMID: 15826219; PubMed Central PMCID: PMC1069649.


Ayad NG, Rankin S, Ooi D, Rape M, Kirschner MW. Identification of ubiquitin ligase substrates by in vitro expression cloning. Methods Enzymol. 2005;399:404-14. PMID: 16338372


Clarke AS, Tang TT, Ooi DL, Orr-Weaver TL. POLO kinase regulates the Drosophila centromere cohesion protein MEI-S332. Dev Cell. 2005 Jan;8(1):53-64. PMID: 15621529


Pacholec M, Freel Meyers CL, Oberthür M, Kahne D, Walsh CT. Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway. Biochemistry. 2005 Mar 29;44(12):4949-56. PMID: 15779922


Pacholec M, Hillson NJ, Walsh CT. NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis. Biochemistry. 2005 Sep 27;44(38):12819-26. PMID: 16171397


Pacholec M, Tao J, Walsh CT. CouO and NovO: C-methyltransferases for tailoring the aminocoumarin scaffold in coumermycin and novobiocin antibiotic biosynthesis. Biochemistry. 2005 Nov 15;44(45):14969-76. PMID: 16274243


Paust S, Cantor H. Regulatory T cells and autoimmune disease. Immunol Rev. 2005 Apr;204:195-207. Review. PubMed PMID: 15790360.


Vincent MS, Xiong X, Grant EP, Peng W, Brenner MB. CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens. J Immunol. 2005 Nov 15;175(10):6344-51. PubMed PMID: 16272286.


Landsberg RL, Awatramani RB, Hunter NL, Farago AF, DiPietrantonio HJ, Rodriguez CI, Dymecki SM. Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6. Neuron. 2005 Dec 22;48(6):933-47. PubMed PMID: 16364898.


Song B, Diaz-Griffero F, Park DH, Rogers T, Stremlau M, Sodroski J. TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity. Virology. 2005 Dec 20;343(2):201-11. Epub 2005 Sep 22. PMID: 16183097


Rooney S, Alt FW, Sekiguchi J, Manis JP. Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2471-5. Epub 2005 Feb 7. PMID: 15699324.


Zucchelli S, Holler P, Yamagata T, Roy M, Benoist C, Mathis D. Defective central tolerance induction in NOD mice: genomics and genetics. Immunity. 2005 Mar;22(3):385-96. PMID: 15780994.


Ohmura K, Johnsen A, Ortiz-Lopez A, Desany P, Roy M, Besse W, Rogus J, Bogue M, Puech A, Lathrop M, Mathis D, Benoist C. Variation in IL-1beta gene expression is a major determinant of genetic differences in arthritis aggressivity in mice. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12489-94. Epub 2005 Aug 19. PubMed PMID: 16113081; PubMed Central PMCID: PMC1194932.


Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R, Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. J Immunol. 2005 Aug 1;175(3):1558-65. PubMed PMID: 16034094.


Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Tim-2 regulates T helper type 2 responses and autoimmunity. J Exp Med. 2005 Aug 1;202(3):437-44. Epub 2005 Jul 25. Erratum in: J Exp Med. 2005 Sep 19;202(6):877. PubMed PMID: 16043519; PubMed Central PMCID: PMC2213076.


Safo PK, Regehr WG. Endocannabinoids control the induction of cerebellar LTD. Neuron. 2005 Nov 23;48(4):647-59. PubMed PMID: 16301180.


Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. A genetic screen for candidate tumor suppressors identifies REST. Cell. 2005 Jun 17;121(6):837-48. PubMed PMID: 15960972.


Halin C, Scimone ML, Bonasio R, Gauguet JM, Mempel TR, Quackenbush E, Proia RL, Mandala S, von Andrian UH. The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches. Blood. 2005 Aug 15;106(4):1314-22. Epub 2005 May 3. PubMed PMID: 15870184; PubMed Central PMCID: PMC1895188.


Walsh DM, Klyubin I, Shankar GM, Townsend M, Fadeeva JV, Betts V, Podlisny MB, Cleary JP, Ashe KH, Rowan MJ, Selkoe DJ. The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention. Biochem Soc Trans. 2005 Nov;33(Pt 5):1087-90. Review. PubMed PMID: 16246051.


Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, Spooner ET, Jiang L, Anwyl R, Selkoe DJ, Rowan MJ. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med. 2005 May;11(5):556-61. Epub 2005 Apr 17. PubMed PMID: 15834427.


Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, El Agnaf O, Hartley DM, Selkoe DJ. Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation. J Neurosci. 2005 Mar 9;25(10):2455-62. Erratum in: J Neurosci. 2005 May 4;25(18):4658. PubMed PMID: 15758153.


Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, Ashe KH. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat Neurosci. 2005 Jan;8(1):79-84. Epub 2004 Dec 19. PubMed PMID: 15608634.


Shen J, Walsh CA. Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice. Mol Cell Biol. 2005 May;25(9):3639-47. PubMed PMID: 15831469; PubMed Central PMCID: PMC1084278.


Shen J, Eyaid W, Mochida GH, Al-Moayyad F, Bodell A, Woods CG, Walsh CA. ASPM mutations identified in patients with primary microcephaly and seizures. J Med Genet. 2005 Sep;42(9):725-9. PubMed PMID: 16141009; PubMed Central PMCID: PMC1736131.


Allan DW, Park D, St Pierre SE, Taghert PH, Thor S. Regulators acting in combinatorial codes also act independently in single differentiating neurons. Neuron. 2005 Mar 3;45(5):689-700. PubMed PMID: 15748845.


Stanford JS, Ruderman JV. Changes in regulatory phosphorylation of Cdc25C Ser287 and Wee1 Ser549 during normal cell cycle progression and checkpoint arrests. Mol Biol Cell. 2005 Dec;16(12):5749-60. Epub 2005 Sep 29. PMID: 16195348 PMCID: PMC1289418 read article


Stolt PC, Chen Y, Liu P, Bock HH, Blacklow SC, Herz J. Phosphoinositide binding by the disabled-1 PTB domain is necessary for membrane localization and Reelin signal transduction. J Biol Chem. 2005 Mar 11;280(10):9671-7. Epub 2005 Jan 4. PMID: 15632144


Lord GM, Rao RM, Choe H, Sullivan BM, Lichtman AH, Luscinskas FW, Glimcher LH. T-bet is required for optimal pro-inflammatoy CD4+ T cell trafficking. Blood. 106(10):3432-9, 2005.


Sullivan BM***, Jobe O***, Lazarevic V***, Vasquez K, Bronson R, Glimcher LH, Kramnik Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. J. Immunol. 175(7):4593-602, 2005.


Woodberry T, Suscovich TJ, Henry LM, Davis JK, Frahm N, Walker BD, Scadden DT, Wang F, Brander C. Differential targeting and shifts in the immunodominance of Epstein-Barr virus--specific CD8 and CD4 T cell responses during acute and persistent infection. J Infect Dis. 2005 Nov 1;192(9):1513-24. Epub 2005 Sep 26. PMID: 16206065


Woodberry T, Suscovich TJ, Henry LM, Martin JN, Dollard S, O'Connor PG, Davis JK, Osmond D, Lee TH, Kedes DH, Khatri A, Lee J, Walker BD, Scadden DT, Brander C. Impact of Kaposi sarcoma-associated herpesvirus (KSHV) burden and HIV coinfection on the detection of T cell responses to KSHV ORF73 and ORF65 proteins. J Infect Dis. 2005 Aug 15;192(4):622-9. Epub 2005 Jul 15. PMID: 16028131


Brodsky AS, Meyer CA, Swinburne IA, Hall G, Keenan BJ, Liu XS, Fox EA, Silver PA. Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells. PMID: 16086846 PMCID: PMC1273631 read article


Tolias KF, Bikoff JB, Burette A, Paradis S, Harrar D, Tavazoie S, Weinberg RJ, Greenberg ME. The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines. Neuron. 2005 Feb 17;45(4):525-38. PubMed PMID: 15721239.


Tavazoie SF, Alvarez VA, Ridenour DA, Kwiatkowski DJ, Sabatini BL. Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2. Nat Neurosci. 2005 Dec;8(12):1727-34. Epub 2005 Nov 6. PubMed PMID: 16286931.


Olesky M, McNamee EE, Zhou C, Taylor TJ, Knipe DM. Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins. Virology. 2005 Jan 5;331(1):94-105. PMID: 15582656


Medoff BD, Thomas SY, Banerji A, Wain JC, Zhang H, Lilly CM, Ginns LC, Luster AD. Pathogenic T-cell recruitment into the airway in human disease. Ann N Y Acad Sci. 2005 Dec;1062:220-41. PMID: 16461804


Bromley SK, Thomas SY, Luster AD. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat Immunol. 2005 Sep;6(9):895-901. Epub 2005 Aug 14. PMID: 16116469


Medoff BD, Seung E, Wain JC, Means TK, Campanella GS, Islam SA, Thomas SY, Ginns LC, Grabie N, Lichtman AH, Tager AM, Luster AD. BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation. J Exp Med. 2005 Jul 4;202(1):97-110. PMID: 15998790 PMCID: PMC2212891 read article


Tischfield MA, Bosley TM, Salih MA, Alorainy IA, Sener EC, Nester MJ, Oystreck DT, Chan WM, Andrews C, Erickson RP, Engle EC. Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development. Nat Genet. 2005 Oct;37(10):1035-7. Epub 2005 Sep 11. PubMed PMID: 16155570.


Conway BR, Tsao DY. Color architecture in alert macaque cortex revealed by FMRI. Cereb Cortex. 2006 Nov;16(11):1604-13. Epub 2005 Dec 28. Erratum in: Cereb Cortex. 2006 Dec;16(12):1820. PubMed PMID: 16400160.


Borodovsky A, Ovaa H, Meester WJ, Venanzi ES, Bogyo MS, Hekking BG, Ploegh HL, Kessler BM, Overkleeft HS. Small-molecule inhibitors and probes for ubiquitin- and ubiquitin-like-specific proteases. Chembiochem. 2005 Feb;6(2):287-91. PubMed PMID: 15651044.


Johnnidis JB, Venanzi ES, Taxman DJ, Ting JP, Benoist CO, Mathis DJ. Chromosomal clustering of genes controlled by the aire transcription factor. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7233-8. Epub 2005 May 9. PubMed PMID: 15883360; PubMed Central PMCID: PMC1129145.


Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. The cellular mechanism of Aire control of T cell tolerance. Immunity. 2005 Aug;23(2):227-39. PubMed PMID: 16111640.


Villaseñor J, Benoist C, Mathis D. AIRE and APECED: molecular insights into an autoimmune disease. Immunol Rev. 2005 Apr;204:156-64. Review. PubMed PMID: 15790357.


Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, Dupuy D, Rual JF, Hill DE, Vidal M, Ruvkun G, Kaplan JM. Systematic analysis of genes required for synapse structure and function. Nature. 2005 Jul 28;436(7050):510-7. PubMed PMID: 16049479.


Wang D, Kennedy S, Conte D Jr, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G. Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature. 2005 Jul 28;436(7050):593-7. PubMed PMID: 16049496.


Zheng G, Patolsky F, Cui Y, Wang WU, Lieber CM. Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat Biotechnol. 2005 Oct;23(10):1294-301. Epub 2005 Sep 18. PMID: 16170313


Wang WU, Chen C, Lin KH, Fang Y, Lieber CM. Label-free detection of small-molecule-protein interactions by using nanowire nanosensors. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3208-12. Epub 2005 Feb 16. PMID: 15716362 PMCID: PMC548960 read article


Wein MN, Jones DC, Glimcher LH. Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity. Immunol Rev. 2005 Dec;208:66-79. Review. PMID: 16313341


Shinohara ML, Jansson M, Hwang ES, Werneck MB, Glimcher LH, Cantor H.T-bet- dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17101-6. Epub 2005 Nov 14. PubMed PMID: 16286640; PubMed Central PMCID: PMC1288014.


Whalen BM, Selkoe DJ, Hartley DM. Small non-fibrillar assemblies of amyloid
beta-protein bearing the Arctic mutation induce rapid neuritic degeneration.
Neurobiol Dis. 2005 Nov;20(2):254-66. PubMed PMID: 16242634.


Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Dev Cell. 2005 Jan;8(1):109-16. PMID: 15621534


Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmid B, Paw BH, Shaw GC, Kingsley P, Palis J, Schubert H, Chen O, Kaplan J, Zon LI; Tübingen 2000 Screen Consortium. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature. 2005 Aug 18;436(7053):1035-39. PMID: 16110529


ian T, Woodworth J, Sköld M, Behar SM. In vivo depletion of CD11c+ cells delays the CD4+ T cell response to Mycobacterium tuberculosis and exacerbates the outcome of infection. J Immunol. 2005 Sep 1;175(5):3268-72. PubMed PMID: 16116218.


Kramer A, Yang FC, Kraves S, Weitz CJ. A screen for secreted factors of the
suprachiasmatic nucleus. Methods Enzymol. 2005;393:645-63. PubMed PMID: 15817317.


Koprivica V, Cho KS, Park JB, Yiu G, Atwal J, Gore B, Kim JA, Lin E, Tessier-Lavigne M, Chen DF, He Z. EGFR Activation Mediates Inhibition of Axon Regeneration by Myelin and Chondroitin Sulfate Proteoglycans. Science. 2005 Oct 7;310(5745):106-10. PMID: 16210539.


Park JB**, Yiu G**, Kaneko S, Wang J, Chang J, He Z. A TNF Receptor Family Member, TROY, Is a Coreceptor with Nogo Receptor in Mediating the Inhibitory Activity of Myelin Inhibitors. Neuron. 2005 Feb 3;45(3):345-51. Cover Article. PMID: 15694321. **Denotes equal contribution.


Zhang Y, Reid RC. Single-neuron responses and neuronal decisions in a vernier task. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3507-12. Epub 2005 Feb 22. PubMed PMID: 15728369; PubMed Central PMCID: PMC552948.


top

2004


Sklar PA, Agyemang AF, Monastra R, Kress DR, Metcalf JA, Robinson MR, Masur H, Polis MA.. Five-year follow-up of a cohort of profoundly immunosuppressed patients discontinuing therapy for cytomegalovirus retinitis. AIDS. 2004 Feb 20;18(3):567-9. PMID: 15090813


Altevogt BM, Paul DL. Four classes of intercellular channels between glial cells in the CNS. J Neurosci. 2004 May 5;24(18):4313-23. PubMed PMID: 15128845.


Nelson EA, Walker SR, Alvarez JV, Frank DA. Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification. J Biol Chem. 2004 Dec 24;279(52):54724-30. Epub 2004 Oct 20. PMID: 15498775


Alvarez JV, Frank DA. Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis. Cancer Biol Ther. 2004 Nov;3(11):1045-50. Epub 2004 Nov 22. PMID: 15539936


Loregian A, Appleton BA, Hogle JM, Coen DM. Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit. J Virol. 2004 Sep;78(17):9084-92. PMID: 15308704 PMCID: PMC506919  read article


Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM. The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer. Mol Cell. 2004 Jul 23;15(2):233-44. PMID: 15260974


Loregian A, Appleton BA, Hogle JM, Coen DM. Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44. J Virol. 2004 Jan;78(1):158-67. PMID: 14671097 PMCID: PMC303418 read article


Arnett KL, Harrison SC, Wiley DC. Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment. Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16268-73. Epub 2004 Nov 8. PubMed PMID: 15534202; PubMed Central PMCID: PMC528977.


Yin P, Keirstead ND, Broering TJ, Arnold MM, Parker JS, Nibert ML, Coombs KM. Comparisons of the M1 genome segments and encoded mu2 proteins of different reovirus isolates. Virol J. 2004 Sep 23;1:6. PMID: 15507160 PMCID: PMC524354 read article


Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, Bronson R, Arnold MM, Knipe DM, Finberg RW. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1315-20. Epub 2004 Jan 22. PMID: 14739339 PMCID: PMC337050 read article


Asthana S, King OD, Gibbons FD, Roth FP. Predicting protein complex membership using probabilistic network reliability. Genome Res. 2004 Jun;14(6):1170-5. Epub 2004 May 12. PMID: 15140827 PMCID: PMC419795 read article


Hillson NJ, Balibar CJ, Walsh CT. Catalytically inactive condensation domain C1 is responsible for the dimerization of the VibF subunit of vibriobactin synthetase. Biochemistry. 2004 Sep 7;43(35):11344-51. PMID: 15366944


Steele LN, Balsara ZR, Starnbach MN. Hematopoietic cells are required to initiate a Chlamydia trachomatis-specific CD8+ T cell response. J Immunol. 2004 Nov 15;173(10):6327-37. PMID: 15528372.


Rutishauser RL, Basu AC, Cromarty SI, Kravitz EA. Long-term consequences of agonistic interactions between socially naive juvenile American lobsters (Homarus americanus). Biol Bull. 2004 Dec;207(3):183-7. PubMed PMID: 15616347.


Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP. Phosphoproteomic analysis of the developing mouse brain. Mol Cell Proteomics. 2004 Nov;3(11):1093-101. Epub 2004 Sep 2. PMID: 5345747


Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP. Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12130-5. Epub 2004 Aug 9. PMID: 15302935 PMCID: PMC514446 read article


On M, Billingsley JM, Jouvin MH, Kinet JP. Molecular dissection of the FcRbeta signaling amplifier. J Biol Chem. 2004 Oct 29;279(44):45782-90. Epub 2004 Aug 30. PubMed PMID: 15339926.


Repasky J, Corbett E, Boboila C, Schatz DG. Mutational analysis of terminal ofdeoxynucleotidyl transferase-mediated N-nucleotide addition in V(D)J recombination, J Immunol. 2004;172(9):5478-88. J Immunol. 2004;172(9):5478-88.


Borowski C, Li X, Aifantis I, Gounari F, von Boehmer H. Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development. J Exp Med. 2004 Mar 1;199(5):607-15.


Boyce M, Degterev A, Yuan J. Caspases: an ancient cellular sword of Damocles. Cell Death Differ. 2004 Jan;11(1):29-37. PMID: 14647235


Chen J, Wall NR, Kocher K, Duclos N, Fabbro D, Neuberg D, Griffin JD, Shi Y, Gilliland DG. Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin. J Clin Invest. 2004 Jun;113(12):1784-91. PubMed PMID: 15199413; PubMed Central PMCID: PMC420507.


Call ME, Wucherpfennig KW. Molecular mechanisms for the assembly of the T cell receptor-CD3 complex. Mol Immunol. 2004 Apr;40(18):1295-305. Review. PubMed PMID: 15072848.


Call ME, Pyrdol J, Wucherpfennig KW. Stoichiometry of the T-cell receptor-CD3 complex and key intermediates assembled in the endoplasmic reticulum. EMBO J. 2004 Jun 16;23(12):2348-57. Epub 2004 May 20. PubMed PMID: 15152191; PubMed Central PMCID: PMC423287.


Carter AG, Sabatini BL. State-dependent calcium signaling in dendritic spines of striatal medium spiny neurons. Neuron. 2004 Oct 28;44(3):483-93. PubMed PMID: 15504328.


Catapano LA, Arlotta P, Cage TA, Macklis JD. Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry. Eur J Neurosci. 2004 May;19(9):2421-34. PubMed PMID: 15128396.


Chae TH, Kim S, Marz KE, Hanson PI, Walsh CA. The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004 Mar;36(3):264-70. Epub 2004 Feb 1. Erratum in: Nat Genet. 2004 Apr;36(4):427. PubMed PMID: 14758363.


Hamar P, Song E, Kokeny G, Chen A, Ouyang N, Lieberman J. Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14883-8.


Deng LW, Chiu I, Strominger JL. MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):757-62. Epub 2004 Jan 12. PMID: 14718661.


Zhang M, Austen WG Jr, Chiu I, Alicot EM, Hung R, Ma M, Verna N, Xu M, Hechtman HB, Moore FD Jr, Carroll MC. Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3886-91. Epub 2004 Mar 3. PMID: 14999103.


Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC. Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex. Nat Cell Biol. 2004 Oct;6(10):991-6. Epub 2004 Sep 26. PubMed PMID: 15448702.


Chou TC, Rotman SR, Saper CB. Lateral hypothalamic acetylcholinesterase-immunoreactive neurons co-express either orexin or melanin concentrating hormone. Neurosci Lett. 2004 Nov 11;370(2-3):123-6. PubMed PMID: 15488307.


Gerashchenko D, Chou TC, Blanco-Centurion CA, Saper CB, Shiromani PJ. Effects of lesions of the histaminergic tuberomammillary nucleus on spontaneous sleep in rats. Sleep. 2004 Nov 1;27(7):1275-81. PubMed PMID: 15586780; PubMed Central PMCID: PMC1249486.


Chyung JH, Raper DM, Selkoe DJ. Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage. J Biol Chem. 2005 Feb 11;280(6):4383-92. Epub 2004 Nov 29. PubMed PMID: 15569674.


Ciccone DN, Morshead KB, Oettinger MA. Chromatin immunoprecipitation in the analysis of large chromatin domains across murine antigen receptor loci. Methods Enzymol. 2004;376:334-48. Review. PubMed PMID: 14975316.


Claypool SM, Dickinson BL, Wagner J, Johansen FE, Nanda Venu, Borawski J, Lencer WI, Blumberg RS. Bi-directional Transepithelial IgG Transport by a Strongly Polarized Basolateral Membrane Fcg-Receptor. Mol. Biol. Cell. 2004 Apr;15(4): 1746-59. PMCID: PMC379272.


Yoshida M, Claypool SM, Wagner JS, Mizoguchi E, Mizoguchi A, Roopenian DC, Lencer WI, Blumberg RS. Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity. 2004 Jun;20(6): 769-83. PMID: 1518974.


Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D*. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell. 2004 Dec 17;119(6):789-802. PubMed PMID: 15607976.


Cooper EM, Hudson AW, Amos J, Wagstaff J, Howley PM. Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. J Biol Chem. 2004 Sep 24;279(39):41208-17. Epub 2004 Jul 19. PubMed PMID: 15263005.


Cortés M, Georgopoulos K. Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity. J Exp Med. 2004 Jan 19;199(2):209-19. Epub 2004 Jan 12. PubMed PMID: 14718515; PubMed Central PMCID: PMC2211773.


Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, Rathnavalu P, Moore C, Pfafferott KJ, Hilton L, Zimbwa P, Moore S, Allen T, Brander C, Addo MM, Altfeld M, James I, Mallal S, Bunce M, Barber LD, Szinger J, Day C, Klenerman P, Mullins J, Korber B, Coovadia HM, Walker BD, Goulder PJ. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature. 2004 Dec 9;432(7018):769-75. PMID 15592417


Lauer GM, Barnes E, Lucas M, Timm J, Ouchi K, Kim AY, Day CL, Robbins GK, Casson DR, Reiser M, Dusheiko G, Allen TM, Chung RT, Walker BD, Klenerman P. High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. Gastroenterology. 2004 Sep;127(3):924-36. PMID: 15362047


Völgyi B, Deans MR, Paul DL, Bloomfield SA. Convergence and segregation of the multiple rod pathways in mammalian retina. J Neurosci. 2004 Dec
8;24(49):11182-92. PubMed PMID: 15590935; PubMed Central PMCID: PMC2834589.


Dekker JP, Fodor A, Aldrich RW, Yellen G. A perturbation-based method for calculating explicit likelihood of evolutionary co-variance in multiple sequence alignments. Bioinformatics. 2004 Jul 10;20(10):1565-72. Epub 2004 Feb 12. PubMed PMID: 14962924.


Webster SM, Del Camino D, Dekker JP, Yellen G. Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges. Nature. 2004 Apr 22;428(6985):864-8. PubMed PMID: 15103379.


Ansel KM, Greenwald RJ, Agarwal S, Bassing CH, Monticelli S, Interlandi J, Djuretic IM, Lee DU, Sharpe AH, Alt FW, Rao A. Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity. Nat Immunol. 2004 Dec;5(12):1251-9. Epub 2004 Oct 31. PubMed PMID: 15516924.


Do MT, Bean BP. Sodium currents in subthalamic nucleus neurons from Nav1.6-null mice. J Neurophysiol. 2004 Aug;92(2):726-33. Epub 2004 Mar 31. PubMed PMID: 15056687.


Miller AJ, Du J, Rowan S, Hershey CL, Widlund HR, Fisher DE. Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma. Cancer Res. 2004 Jan 15;64(2):509-16. PMID: 14744763


Vetrini F, Auricchio A, Du J, Angeletti B, Fisher DE, Ballabio A, Marigo V. The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis. Mol Cell Biol. 2004 Aug;24(15):6550-9. PMID: 15254223 PMCID: PMC444869 read article


Du J, Widlund HR, Horstmann MA, Ramaswamy S, Ross K, Huber WE, Nishimura EK, Golub TR, Fisher DE. Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF. Cancer Cell. 2004 Dec;6(6):565-76. PMID: 15607961


Bentires-Alj M, Paez JG, David FS, Keilhack H, Halmos B, Naoki K, Maris JM, Richardson A, Bardelli A, Sugarbaker DJ, Richards WG, Du J, Girard L, Minna JD, Loh ML, Fisher DE, Velculescu VE, Vogelstein B, Meyerson M, Sellers WR, Neel BG. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia. Cancer Res. 2004 Dec 15;64(24):8816-20. PMID: 15604238


Talukder SR, Dudley DD, Alt FW, Takahama Y, Akamatsu Y. Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice. Nucleic Acids Res. 2004 Aug 24;32(15):4539-49. Print 2004. PMID: 15328366.


Everley PA, Krijgsveld J, Zetter BR, Gygi SP. Quantitative cancer proteomics: stable isotope labeling with amino acids in cell culture (SILAC) as a tool for prostate cancer research. Mol Cell Proteomics. 2004 Jul;3(7):729-35. Epub 2004 Apr 21. PMID: 15102926


Fontaine-Rodriguez EC, Taylor TJ, Olesky M, Knipe DM. Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. Virology. 2004 Dec 20;330(2):487-92. PMID: 15567442


Foster KA, Regehr WG. Variance-mean analysis in the presence of a rapid antagonist indicates vesicle depletion underlies depression at the climbing fiber synapse. Neuron. 2004 Jul 8;43(1):119-31. PubMed PMID: 15233922.


Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science. 2004 Aug 27;305(5688):1292-5. PMID: 15333840


Li S, Armstrong CM, Bertin N, Ge H, Milstein S, Boxem M, Vidalain PO, Han JD, Chesneau A, Hao T, Goldberg DS, Li N, Martinez M, Rual JF, Lamesch P, Xu L, Tewari M, Wong SL, Zhang LV, Berriz GF, Jacotot L, Vaglio P, Reboul J, Hirozane-Kishikawa T, Li Q, Gabel HW, Elewa A, Baumgartner B, Rose DJ, Yu H, Bosak S, Sequerra R, Fraser A, Mango SE, Saxton WM, Strome S, Van Den Heuvel S, Piano F, Vandenhaute J, Sardet C, Gerstein M, Doucette-Stamm L, Gunsalus KC, Harper JW, Cusick ME, Roth FP, Hill DE, Vidal M. A map of the interactome network of the metazoan C. elegans. Science. 2004 Jan 23;303(5657):540-3. Epub 2004 Jan 2. PubMed PMID: 14704431; PubMed Central PMCID: PMC1698949.


Crane R, Gadea B, Littlepage L, Wu H, Ruderman JV. Aurora A, meiosis and mitosis. Biol Cell. 2004 Apr;96(3):215-29. PMID: 15182704


Giraud J, Leshan R, Lee YH, White MF. Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling. J Biol Chem. 2004 Jan 30;279(5):3447-54. Epub 2003 Nov 17. PMID: 14623899


Gregory BD, Nickels BE, Garrity SJ, Severinova E, Minakhin L, Urbauer RJ, Urbauer JL, Heyduk T, Severinov K, Hochschild A. A regulator that inhibits transcription by targeting an intersubunit interaction of the RNA polymerase holoenzyme. PMID: 15070756 PMCID: PMC384785 read article


Pineda M, Gregory BD, Szczypinski B, Baxter KR, Hochschild A, Miller ES, Hinton DM. A family of anti-sigma70 proteins in T4-type phages and bacteria that are similar to AsiA, a Transcription inhibitor and co-activator of bacteriophage T4. J Mol Biol. 2004 Dec 10;344(5):1183-97. PMID: 15561138


Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE. Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol. 2004 Aug;6(8):709-20. Epub 2004 Jul 18. PubMed PMID: 15258588.


Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. Genomic analysis of mouse retinal development. PLoS Biol. 2004 Sep;2(9):E247. Epub 2004 Jun 29. PubMed PMID: 15226823; PubMed Central PMCID: PMC439783.


Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):360-5. Epub 2003 Dec 22. PMID: 14691248 PMCID: PMC314190 read article


Heerssen HM, Pazyra MF, Segal RA. Dynein motors transport activated Trks to promote survival of target-dependent neurons. Nat Neurosci. 2004 Jun;7(6):596-604. Epub 2004 May 2. PubMed PMID: 15122257.


Mempel TR, Henrickson SE, Von Andrian UH. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature. 2004 Jan 8;427(6970):154-9. PMID: 14712275


Cahir-McFarland ED, Carter K, Rosenwald A, Giltnane JM, Henrickson SE, Staudt LM, Kieff E. Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells. J Virol. 2004 Apr;78(8):4108-19. PMID: 15047827 PMCID: PMC374271


Andres PG, Howland KC, Nirula A, Kane LP, Barron L, Dresnek D, Sadra A, Imboden J, Weiss A, Abbas AK. Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nat Immunol. 2004 Apr;5(4):435-42. Epub 2004 Mar 7.


Andres PG, Howland KC, Dresnek D, Edmondson S, Abbas AK, Krummel MF. CD28 signals in the immature immunological synapse. J Immunol. 2004 May 15;172(10):5880-6.


Jackson AC, Yao GL, Bean BP. Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons. J Neurosci. 2004 Sep 15;24(37):7985-98. PubMed PMID: 15371499.


Seaman MS, Peyerl FW, Jackson SS, Lifton MA, Gorgone DA, Schmitz JE, Letvin NL. Subsets of memory cytotoxic T lymphocytes elicited by vaccination influence the efficiency of secondary expansion in vivo. J Virol. 2004 Jan;78(1):206-15. PubMed PMID: 14671102; PubMed Central PMCID: PMC303428.


Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol. 2004 Mar;78(6):2666-73. PubMed PMID: 14990686; PubMed Central PMCID: PMC353774.


McKay PF, Barouch DH, Santra S, Sumida SM, Jackson SS, Gorgone DA, Lifton MA, Letvin NL. Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses. Eur J Immunol. 2004 Apr;34(4):1011-20. PubMed PMID: 15048711.


Sumida SM, McKay PF, Truitt DM, Kishko MG, Arthur JC, Seaman MS, Jackson SS, Gorgone DA, Lifton MA, Letvin NL, Barouch DH. Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines. J Clin Invest. 2004 Nov;114(9):1334-42. PubMed PMID: 15520866; PubMed Central PMCID: PMC524232.


Peacock JW, Nordone SK, Jackson SS, Liao HX, Letvin NL, Yafal AG, Gritz L, Mazzara GP, Haynes BF, Staats HF. Gender differences in human immunodeficiency virus type 1-specific CD8 responses in the reproductive tract and colon following nasal peptide priming and modified vaccinia virus Ankara boosting. J Virol. 2004 Dec;78(23):13163-72. PubMed PMID: 15542668; PubMed Central PMCID: PMC524967.


Sumida SM, Truitt DM, Kishko MG, Arthur JC, Jackson SS, Gorgone DA, Lifton MA, Koudstaal W, Pau MG, Kostense S, Havenga MJ, Goudsmit J, Letvin NL, Barouch DH. Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol. 2004 Mar;78(6):2666-73. PubMed PMID: 14990686; PubMed Central PMCID: PMC353774.


Sakata Y, Xiang F, Chen Z, Kiriyama Y, Kamei CN, Simon DI, Chin MT. Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro. Arterioscler Thromb Vasc Biol. 2004 Nov;24(11):2069-74. Epub 2004 Sep 2. PubMed PMID: 15345511.


Fraering PC, LaVoie MJ, Ye W, Ostaszewski BL, Kimberly WT, Selkoe DJ, Wolfe MS. Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex. Biochemistry. 2004 Jan 20;43(2):323-33. PubMed PMID: 14717586.


Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J. Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. J Neurosci. 2004 Feb 25;24(8):1897-906. PubMed PMID: 14985430.


Chylack LT Jr, Fu L, Mancini R, Martin-Rehrmann MD, Saunders AJ, Konopka G, Tian D, Hedley-Whyte ET, Folkerth RD, Goldstein LE. Lens epithelium-derived growth factor (LEDGF/p75) expression in fetal and adult human brain. Exp Eye Res. 2004 Dec;79(6):941-8. PubMed PMID: 15642333.


He Z, Koprivica V. The Nogo signaling pathway for regeneration block. Annu Rev Neurosci. 2004;27:341-68. Review. PubMed PMID: 15217336.


Morris JR, Petrov DA, Lee AM, Wu CT. Enhancer choice in cis and in trans in Drosophila melanogaster: role of the promoter. Genetics. 2004 Aug;167(4):1739-47. PubMed PMID: 15342512; PubMed Central PMCID: PMC1471007.


Kowalski MP, Pier GB. Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. J Immunol. 2004 Jan 1;172(1):418-25. PMID: 14688350


Labonte ML, Letvin NL. Variable NKG2 expression in the peripheral blood lymphocytes of rhesus monkeys. Clin Exp Immunol. 2004 Nov;138(2):205-12. PMID: 15498028 PMCID: PMC1809222 read article


LaBonte ML, Choi EI, Letvin NL. Molecular determinants regulating the pairing of NKG2 molecules with CD94 for cell surface heterodimer expression. J Immunol. 2004 Jun 1;172(11):6902-12. PMID: 15153509


Nardone J, Lee DU, Ansel KM, Rao A. Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA. Nat Immunol. 2004 Aug;5(8):768-74. Review. PubMed PMID: 15282556.


Lee DU, Rao A. Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):16010-5. Epub 2004 Oct 26. PubMed PMID: 15507491; PubMed Central PMCID: PMC528768.


Ansel KM, Greenwald RJ, Agarwal S, Bassing CH, Monticelli S, Interlandi J, Djuretic IM, Lee DU, Sharpe AH, Alt FW, Rao A. Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity. Nat Immunol. 2004 Dec;5(12):1251-9. Epub 2004 Oct 31. PubMed PMID: 15516924.


Yuan H, Liddle FJ, Mahajan S, Frank DA. IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor. Carcinogenesis. 2004 Nov;25(11):2247-55. Epub 2004 Jul 29. PMID: 15284182


Matthews AG, Elkin SK, Oettinger MA. Ordered DNA release and target capture in RAG transposition. EMBO J. 2004 Mar 10;23(5):1198-206. Epub 2004 Feb 26. PubMed PMID: 14988730; PubMed Central PMCID: PMC380985.


McKee AE, Silver PA. REF-ereeing the cytoplasmic fate of mRNA via nuclear export. Dev Cell. 2004 Jun;6(6):740-2. PMID: 15177019


Melroe GT, DeLuca NA, Knipe DM. Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J Virol. 2004 Aug;78(16):8411-20. PMID: 15280450 PMCID: PMC479070 read article


Misaghi S, Sun ZY, Stern P, Gaudet R, Wagner G, Ploegh H. Structural and functional analysis of human cytomegalovirus US3 protein. J Virol. 2004 Jan;78(1):413-23. PMID: 14671122 PMCID: PMC303419 read article


Hirsch C, Misaghi S, Blom D, Pacold ME, Ploegh HL. Yeast N-glycanase distinguishes between native and non-native glycoproteins. EMBO Rep. 2004 Feb;5(2):201-6. Epub 2004 Jan 9. PMID: 14726951 PMCID: PMC1298977 read article


Misaghi S, Pacold ME, Blom D, Ploegh HL, Korbel GA. Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. Chem Biol. 2004 Dec;11(12):1677-87. PMID: 15610852


Miyamoto DT, Perlman ZE, Burbank KS, Groen AC, Mitchison TJ. The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. J Cell Biol. 2004 Dec 6;167(5):813-8. PMID: 15583027 PMCID: PMC2172449 read article


Groen AC, Cameron LA, Coughlin M, Miyamoto DT, Mitchison TJ, Ohi R. XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Curr Biol. 2004 Oct 26;14(20):1801-11. PMID: 15498487


Natarajan A, Moerke N, Fan YH, Chen H, Christ WJ, Wagner G, Halperin JA. Synthesis of fluorescein labeled 7-methylguanosinemonophosphate. Bioorg Med Chem Lett. 2004 May 17;14(10):2657-60. PMID: 15109672


Norris PJ, Moffett HF, Brander C, Allen TM, O'Sullivan KM, Cosimi LA, Kaufmann DE, Walker BD, Rosenberg ES. Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells. AIDS Res Hum Retroviruses. 2004 Mar;20(3):315-25. PMID: 15117455.


SenGupta D, Norris PJ, Suscovich TJ, Hassan-Zahraee M, Moffett HF, Trocha A, Draenert R, Goulder PJ, Binder RJ, Levey DL, Walker BD, Srivastava PK, Brander C. Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II. J Immunol. 2004 Aug 1;173(3):1987-93. PMID: 15265933


Norris PJ, Moffett HF, Yang OO, Kaufmann DE, Clark MJ, Addo MM, Rosenberg ES. Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells. J Virol. 2004 Aug;78(16):8844-51. PMID: 15280492


Pillai S, Cariappa A, Moran ST. Positive selection and lineage commitment during peripheral B-lymphocyte development. Immunol Rev. 2004. Feb;197:206-18. PMID:14962197.


Moran MM, Xu H, Clapham DE. TRP ion channels in the nervous system. Curr Opin Neurobiol. 2004 Jun;14(3):362-9. Review. PubMed PMID: 15194117.


Ciccone DN, Morshead KB, Oettinger MA. Chromatin immunoprecipitation in the analysis of large chromatin domains across murine antigen receptor loci. Methods Enzymol. 2004;376:334-48. Review. PubMed PMID: 14975316.


Helander A, Miller CL, Myers KS, Neutra MR, Nibert ML. Protective immunoglobulin A and G antibodies bind to overlapping intersubunit epitopes in the head domain of type 1 reovirus adhesin sigma1. J Virol. 2004 Oct;78(19):10695-705. PMID: 15367636 PMCID: PMC516417 read article


Münger K, Baldwin A, Edwards KM, Hayakawa H, Nguyen CL, Owens M, Grace M, Huh K. Mechanisms of human papillomavirus-induced oncogenesis. J Virol. 2004 Nov;78(21):11451-60. Review. PMID: 15479788 PMCID: PMC523272 read article


Schratt GM, Nigh EA, Chen WG, Hu L, Greenberg ME. BDNF regulates the
translation of a select group of mRNAs by a mammalian target of
rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J Neurosci. 2004 Aug 18;24(33):7366-77. PubMed PMID: 15317862.


On M, Billingsley JM, Jouvin MH, Kinet JP. Molecular dissection of the FcRbeta signaling amplifier. J Biol Chem. 2004 Oct 29;279(44):45782-90. Epub 2004 Aug 30. PubMed PMID: 15339926.


Pi N, Meyers CL, Pacholec M, Walsh CT, Leary JA. Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10036-41. Epub 2004 Jun 24. PMID: 15218104 PMCID: PMC454160 read article


Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10398-403. Epub 2004 Jul 2. PubMed PMID: 15235129; PubMed Central PMCID: PMC478583.


McCarty N, Paust S, Ikizawa K, Dan I, Li X, Cantor H. Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes. Nat Immunol. 2005 Jan;6(1):65-72. Epub 2004 Dec 19. Erratum in: Nat Immunol. 2005 Feb;6(2):219. PubMed PMID: 15608642.


Poulin DL, Kung AL, DeCaprio JA. p53 targets simian virus 40 large T antigen for acetylation by CBP. J Virol. 2004 Aug;78(15):8245-53. PMID: 15254196 PMCID: PMC446111 read article


Radosevich M, Song Z, Gorga JC, Ksander B, Ono SJ. Epigenetic silencing of the CIITA gene and posttranscriptional regulation of class II MHC genes in ocular melanoma cells. Invest Ophthalmol Vis Sci. 2004 Sep;45(9):3185-95. PMID: 15326139


Radosevich M, Ono SJ. MHC class II gene expression is not induced in HPIV3-infected respiratory epithelial cells. Immunol Res. 2004;30(2):125-38. PMID: 15477655.


Kraft S, Rana S, Jouvin MH, Kinet JP. The role of the FcepsilonRI beta-chain in allergic diseases. Int Arch Allergy Immunol. 2004 Sep;135(1):62-72. Epub 2004 Aug 13. Review. PMID: 15316148.


Ghosh AK, Reddi AL, Rao NL, Duan L, Band V, Band H. Biochemical basis for the requirement of kinase activity for Cbl-dependent ubiquitinylation and degradation of a target tyrosine kinase. J Biol Chem. 2004 Aug 20;279(34):36132-41. Epub 2004 Jun 18. PubMed PMID: 15208330.


Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jäger S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell. 2004 Oct 1;119(1):121-35. PMID: 15454086


Rooney S, Sekiguchi J, Whitlow S, Eckersdorff M, Manis JP, Lee C, Ferguson DO, Alt FW. Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2410-5. PMID: 14983023.


Rooney S, Chaudhuri J, Alt FW. The role of the non-homologous end-joining pathway in lymphocyte development. Immunol Rev. 2004 Aug;200:115-31. Review. PMID: 15242400.


Brown SP, Safo PK, Regehr WG. Endocannabinoids inhibit transmission at granule cell to Purkinje cell synapses by modulating three types of presynaptic calcium channels. J Neurosci. 2004 Jun 16;24(24):5623-31. PubMed PMID: 15201335.


Samuels BA, Tsai LH. Nucleokinesis illuminated. Nat Neurosci. 2004 Nov;7(11):1169-70. PubMed PMID: 15508010.


Schwabish MA, Struhl K. Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II. Mol Cell Biol. 2004 Dec;24(23):10111-7. PMID: 15542822 PMCID: PMC529037 read article


Scimone ML, Felbinger TW, Mazo IB, Stein JV, Von Andrian UH, Weninger W. CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes. J Exp Med. 2004 Apr 19;199(8):1113-20. PubMed PMID: 15096537; PubMed Central PMCID: PMC2211897.


Smith JG, Mothes W, Blacklow SC, Cunningham JM. The mature avian leucosis virus subgroup A envelope glycoprotein is metastable, and refolding induced by the synergistic effects of receptor binding and low pH is coupled to infection. J Virol. 2004 Feb;78(3):1403-10. PubMed PMID: 14722295; PubMed Central PMCID: PMC321377.


Monticelli S, Solymar DC, Rao A. Role of NFAT proteins in IL13 gene transcription in mast cells. J Biol Chem. 2004 Aug 27;279(35):36210-8. Epub 2004 Jun 30. PMID: 15229217.


Steele LN, Balsara ZR, Starnbach MN. Hematopoietic cells are required to initiate a Chlamydia trachomatis-specific CD8+ T cell response. J Immunol. 2004 Nov 15;173(10):6327-37. PubMed PMID: 15528372.


Stolt PC, Vardar D, Blacklow SC. The dual-function disabled-1 PTB domain exhibits site independence in binding phosphoinositide and peptide ligands. Biochemistry. 2004 Aug 31;43(34):10979-87. PMID: 15323557


Su MW, Pyarajan S, Chang JH, Yu CL, Jin YJ, Stierhof YD, Walden P, Burakoff SJ. Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing. Eur J Immunol. 2004 Sep;34(9):2459-70. PMID: 15307178.


Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J. Exp. Med. 200(1):79-87, 2004.


INVITED PUBLICATIONS (non-peer reviewed): Glimcher LH, Townsend MJ, Sullivan BM, Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells. Nat. Rev. Immunol. 4(11):900-11, 2004.


Lu Q, Sun EE, Flanagan JG. Analysis of PDZ-RGS3 function in ephrin-B reverse signaling. Methods Enzymol. 2004;390:120-8. PMID: 15488174


Suscovich TJ, Paulose-Murphy M, Harlow JD, Chen Y, Thomas SY, Mellott TJ, Walker BD, Scadden DT, Zeichner S, Brander C. Defective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles. Leuk Lymphoma. 2004 Jun;45(6):1223-38. PMID: 15360006


Fontaine-Rodriguez EC, Taylor TJ, Olesky M, Knipe DM. Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. Virology. 2004 Dec 20;330(2):487-92. PMID: 15567442


Taylor TJ, Knipe DM. Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. J Virol. 2004 Jun;78(11):5856-66. PMID: 15140983 PMCID: PMC415816 read article


Hess C, Altfeld M, Thomas SY, Addo MM, Rosenberg ES, Allen TM, Draenert R, Eldrige RL, van Lunzen J, Stellbrink HJ, Walker BD, Luster AD. HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication. Lancet. 2004 Mar 13;363(9412):863-6. PMID: 15031033


Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 2004 Mar 26;303(5666):2011-5. Epub 2004 Feb 19. PubMed PMID: 14976264.
"


Trinidad JC, Cohen JB. Neuregulin inhibits acetylcholine receptor aggregation in myotubes. J Biol Chem. 2004 Jul 23;279(30):31622-8. Epub 2004 May 20. PubMed PMID: 15155732.


Tseng CC, McLoughlin SM, Kelleher NL, Walsh CT. Role of the active site cysteine of DpgA, a bacterial type III polyketide synthase. Biochemistry. 2004 Feb 3;43(4):970-80.


Tseng CC, Vaillancourt FH, Bruner SD, Walsh CT. DpgC is a metal- and cofactor-free 3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase in the vancomycin biosynthetic pathway. Chem Biol. 2004 Sep;11(9):1195-203. PMID: 15380180


Perron MJ, Stremlau M, Song B, Ulm W, Mulligan RC, Sodroski J. TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11827-32. Epub 2004 Jul 27. PMID: 15280539 PMCID: PMC511059 read article


Venanzi ES, Benoist C, Mathis D. Good riddance: Thymocyte clonal deletion prevents autoimmunity. Curr Opin Immunol. 2004 Apr;16(2):197-202. PubMed PMID: 15023413.


Kennedy S, Wang D, Ruvkun G. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature. 2004 Feb 12;427(6975):645-9. PubMed PMID: 14961122.


Wang D, Ruvkun G. Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway. Cold Spring Harb Symp Quant Biol. 2004;69:429-31. PubMed PMID: 16117677.


Sivasankaran R, Pei J, Wang KC, Zhang YP, Shields CB, Xu XM, He Z. PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration. Nat Neurosci. 2004 Mar;7(3):261-8. Epub 2004 Feb 8. PubMed PMID: 14770187.


Webster SM, Del Camino D, Dekker JP, Yellen G. Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges. Nature. 2004 Apr 22;428(6985):864-8. PubMed PMID: 15103379.


Oukka M, Wein MN, Glimcher LH. Schnurri-3 (KRC) Interacts with c-Jun to Regulate the IL-2 Gene in T Cells. J Exp Med. 2004 Jan 5;199(1):15-24.PMID: 14707112 PMCID: PMC1887724


Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X, Zhou Y, Zon LI. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development. 2004 Dec;131(24):6225-35. PMID: 15563524


Kamath AB, Woodworth J, Xiong X, Taylor C, Weng Y, Behar SM. Cytolytic CD8+ T cells recognizing CFP10 are recruited to the lung after Mycobacterium tuberculosis infection. J Exp Med. 2004 Dec 6;200(11):1479-89. Epub 2004 Nov 22. PubMed PMID: 15557351; PubMed Central PMCID: PMC2211947.


top

2003


Miller CL, Broering TJ, Parker JS, Arnold MM, Nibert ML. Reovirus sigma NS protein localizes to inclusions through an association requiring the mu NS amino terminus. J Virol. 2003 Apr;77(8):4566-76. PMID: 12663763 PMCID: PMC152138 read article


Basu AC, Kravitz EA. Morphology and monoaminergic modulation of Crustacean Hyperglycemic Hormone-like immunoreactive neurons in the lobster nervous system. J Neurocytol. 2003 Mar;32(3):253-63. PubMed PMID: 14724388.


Blair NT, Bean BP. Role of tetrodotoxin-resistant Na+ current slow inactivation in adaptation of action potential firing in small-diameter dorsal root ganglion neurons. J Neurosci. 2003 Nov 12;23(32):10338-50. PubMed PMID: 14614093.


Schott E, Bonasio R, Ploegh HL (2003). Elimination in vivo of developing T cells by natural killer cells. Journal of Experimental Medicine 198:1213-24. PMID: 14568980; PMCID: PMC2194238.


Sicinska E, Aifantis I, Le Cam L, Swat W, Borowski C, Yu Q, Ferrando AA, Levin SD, Geng Y, von Boehmer H, Sicinski P. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell. 2003 Dec;4(6):451-61.


Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene. 2003 Nov 24;22(53):8543-67. PMID: 14634618


Mitra RD, Butty VL, Shendure J, Williams BR, Housman DE, Church GM. Digital genotyping and haplotyping with polymerase colonies. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5926-31. Epub 2003 May 2. PMID: 12730373.


Butty VL, Roux-Lombard P, Garbino J, Dayer JM, Ricou B; Geneva Sepsis Network. Anti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis. Eur Cytokine Netw. 2003 Jan-Mar;14(1):15-9. PMID:12799209.


Carter AR, Berry EM, Segal RA. Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning. Mol Cell Neurosci. 2003 Jan;22(1):1-13. PubMed PMID: 12595234.


Traver D, Herbomel P, Patton EE, Murphey RD, Yoder JA, Litman GW, Catic A, Amemiya CT, Zon LI, Trede NS. The zebrafish as a model organism to study development of the immune system. Adv. Immunol. 2003;81:253-330. Review.


Chan B, Lanyi A, Song HK, Griesbach J, Simarro-Grande M, Poy F, Howie D, Sumegi J, Terhorst C, Eck MJ. SAP couples Fyn to SLAM immune receptors. Nat Cell Biol. 2003 Feb;5(2):155-60. PMID: 12545174


Chamberlin NL, Arrigoni E, Chou TC, Scammell TE, Greene RW, Saper CB. Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons. Neuroscience. 2003;119(4):913-8. PubMed PMID: 12831851.


Chou TC, Scammell TE, Gooley JJ, Gaus SE, Saper CB, Lu J. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci. 2003 Nov 19;23(33):10691-702. PubMed PMID: 14627654.


Chyung JH, Selkoe DJ. Inhibition of receptor-mediated endocytosis demonstrates generation of amyloid beta-protein at the cell surface. J Biol Chem. 2003 Dec 19;278(51):51035-43. Epub 2003 Oct 2. PubMed PMID: 14525989.


Ng HH, Ciccone DN, Morshead KB, Oettinger MA, Struhl K. Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1820-5. Epub 2003 Feb 6. PubMed PMID: 12574507; PubMed Central PMCID: PMC149917.


Morshead KB, Ciccone DN, Taverna SD, Allis CD, Oettinger MA. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11577-82. Epub 2003 Sep 19. PubMed PMID: 14500909; PubMed Central PMCID: PMC208800.


Clatworthy AE, Valencia MA, Haber JE, Oettinger MA. V(D)J recombination and RAG-mediated transposition in yeast. Mol Cell. 2003 Aug;12(2):489-99. PubMed PMID: 14536087.


Maruo S, Johannsen E, Illanes D, Cooper A, Kieff E. Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth. J Virol. 2003 Oct;77(19):10437-47. PMID: 12970429 PMCID: PMC228516 read article


Cooper A, Johannsen E, Maruo S, Cahir-McFarland E, Illanes D, Davidson D, Kieff E. EBNA3A association with RBP-Jkappa down-regulates c-myc and Epstein-Barr virus-transformed lymphoblast growth. J Virol. 2003 Jan;77(2):999-1010. PMID: 12502816 PMCID: PMC140836. read article


Subbramanian RA, Kuroda MJ, Charini WA, Barouch DH, Costantino C, Santra S, Schmitz JE, Martin KL, Lifton MA, Gorgone DA, Shiver JW, Letvin NL. Magnitude and diversity of cytotoxic-T-lymphocyte responses elicited by multiepitope DNA vaccination in rhesus monkeys. J Virol. 2003 Sep;77(18):10113-8. PubMed PMID: 12941922; PubMed Central PMCID: PMC224609.


Day CL, Walker BD. Progress in defining CD4 helper cell responses in chronic viral infections. J Exp Med. 2003 Dec 15;198(12):1773-7. PMID: 14676292 PMCID: PMC2194149  read article


Day CL, Seth NP, Lucas M, Appel H, Gauthier L, Lauer GM, Robbins GK, Szczepiorkowski ZM, Casson DR, Chung RT, Bell S, Harcourt G, Walker BD, Klenerman P, Wucherpfennig KW. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J Clin Invest. 2003 Sep;112(6):831-42. PMID: 12975468 PMCID: PMC193667 read article


Somsouk M, Lauer GM, Casson D, Terella A, Day CL, Walker BD, Chung RT. Spontaneous resolution of chronic hepatitis C virus disease after withdrawal of immunosuppression. Gastroenterology. 2003 Jun;124(7):1946-9. PMID: 12806627


Do MT, Bean BP. Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation. Neuron. 2003 Jul 3;39(1):109-20. PubMed PMID: 12848936.


Zhou P, Fernandes N, Dodge IL, Reddi AL, Rao N, Safran H, DiPetrillo TA, Wazer DE, Band V, Band H. ErbB2 degradation mediated by the co-chaperone protein CHIP. J Biol Chem. 2003 Apr 18;278(16):13829-37. Epub 2003 Feb 6. PubMed PMID:12574167.


Dodge IL, Carr MW, Cernadas M, Brenner MB. IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. J Immunol. 2003 May 1;170(9):4457-64. PubMed PMID: 12707321.


Duan L, Miura Y, Dimri M, Majumder B, Dodge IL, Reddi AL, Ghosh A, Fernandes N, Zhou P, Mullane-Robinson K, Rao N, Donoghue S, Rogers RA, Bowtell D, Naramura M, Gu H, Band V, Band H. Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis. J Biol Chem. 2003 Aug 1;278(31):28950-60. Epub 2003 May 18. PubMed PMID: 12754251.


Du J, Miller AJ, Widlund HR, Horstmann MA, Ramaswamy S, Fisher DE. MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. Am J Pathol. 2003 Jul;163(1):333-43. PMID: 12819038 PMCID: PMC1868174 read article


Huber WE, Price ER, Widlund HR, Du J, Davis IJ, Wegner M, Fisher DE. A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes. J Biol Chem. 2003 Nov 14;278(46):45224-30. Epub 2003 Aug 27. PMID: 12944398


Akamatsu Y, Monroe R, Dudley DD, Elkin SK, Gartner F, Talukder SR, Takahama Y, Alt FW, Bassing CH, Oettinger MA. Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1209-14. Epub 2003 Jan 16. PMID: 12531919.


Dudley DD, Sekiguchi J, Zhu C, Sadofsky MJ, Whitlow S, DeVido J, Monroe RJ, Bassing CH, Alt FW. Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice. J Exp Med. 2003 Nov 3;198(9):1439-50. Epub 2003 Oct 27. PMID: 14581608.


Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell. 2003 Oct 3;115(1):83-95.PMID: 14532005


Elia AE, Cantley LC, Yaffe MB. Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science. 2003 Feb 21;299(5610):1228-31. PMID: 12595692


Fragoso R, Ren D, Zhang X, Su MW, Burakoff SJ, Jin YJ. Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. J Immunol, 170(2):913-21. 2003.


Furman MH, Loureiro J, Ploegh HL, Tortorella D. Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum. J Biol Chem. 2003 Sep 12;278(37):34804-11. Epub 2003 Jun 27. PubMed PMID: 12832421.


Tirosh B, Furman MH, Tortorella D, Ploegh HL. Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation. J Biol Chem. 2003 Feb 28;278(9):6664-72. Epub 2002 Dec 12. PubMed PMID: 12482753.


Chou TC, Scammell TE, Gooley JJ, Gaus SE, Saper CB, Lu J. Critical role of
dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms.J Neurosci. 2003 Nov 19;23(33):10691-702. PubMed PMID: 14627654.


Chou TC, Scammell TE, Gooley JJ, Gaus SE, Saper CB, Lu J. Critical role of
dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci. 2003 Nov 19;23(33):10691-702. PubMed PMID: 14627654.


Lee YH, Giraud J, Davis RJ, White MF. c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade. J Biol Chem. 2003 Jan 31;278(5):2896-902. Epub 2002 Nov 1. PMID: 12417588


Cruz JC, Tseng HC, Goldman JA, Shih H, Tsai LH. Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron. 2003 Oct 30;40(3):471-83. PubMed PMID: 14642273.


Lu C, Huang X, Ma HF, Gooley JJ, Aparacio J, Roof DJ, Chen C, Chen DF, Li T. Normal retinal development and retinofugal projections in mice lacking the retina-specific variant of actin-binding LIM domain protein. Neuroscience. 2003;120(1):121-31. PubMed PMID: 12849746.q


Gooley JJ, Lu J, Fischer D, Saper CB. A broad role for melanopsin in nonvisual photoreception. J Neurosci. 2003 Aug 6;23(18):7093-106. PubMed PMID: 12904470.


Chou TC, Scammell TE, Gooley JJ, Gaus SE, Saper CB, Lu J. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci. 2003 Nov 19;23(33):10691-702. PubMed PMID: 14627654.


Greka A, Navarro B, Oancea E, Duggan A, Clapham DE. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nat Neurosci. 2003 Aug;6(8):837-45. PubMed PMID: 12858178.


Oancea E, Bezzerides VJ, Greka A, Clapham DE. Mechanism of persistent protein kinase D1 translocation and activation. Dev Cell. 2003 Apr;4(4):561-74. PubMed PMID: 12689594.


Griffin RS, Mills CD, Costigan M, Woolf CJ. Exploiting microarrays to reveal differential gene expression in the nervous system. Genome Biol. 2003;4(2):105. Epub 2003 Jan 29. PubMed PMID: 12620110; PubMed Central PMCID: PMC151293.


Harpavat S, Cepko CL. Thyroid hormone and retinal development: an emerging field. Thyroid. 2003 Nov;13(11):1013-9. Review. PubMed PMID: 14651785.


Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J. Computational and experimental identification of C. elegans microRNAs. Mol Cell. 2003 May;11(5):1253-63. PMID: 12769849


Chaput JC, Ichida JK, Szostak JW. DNA polymerase-mediated DNA synthesis on a TNA template. J Am Chem Soc. 2003 Jan 29;125(4):856-7. PubMed PMID: 12537469.


Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA, Lifton MA, Chakrabarti BK, Xu L, Nabel GJ, Letvin NL. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol. 2003 Aug;77(16):8729-35. PubMed PMID: 12885892; PubMed Central PMCID: PMC167238.


Kessler JC, Rochet JC, Lansbury PT Jr. The N-terminal repeat domain of alpha-synuclein inhibits beta-sheet and amyloid fibril formation. Biochemistry. 2003 Jan 28;42(3):672-8. PMID: 12534279


Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. FASEB J. 2003 Jan;17(1):79-81. Epub 2002 Nov 1. PubMed PMID: 12424225.


Kimberly WT, Esler WP, Ye W, Ostaszewski BL, Gao J, Diehl T, Selkoe DJ, Wolfe MS. Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s). Biochemistry. 2003 Jan 14;42(1):137-44. PubMed PMID: 12515548.


Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6382-7. Epub 2003 May 9. PubMed PMID: 12740439; PubMed Central PMCID: PMC164455.


Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ. gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry. 2003 Jun 10;42(22):6664-73. PubMed PMID: 12779321.


LaVoie MJ, Fraering PC, Ostaszewski BL, Ye W, Kimberly WT, Wolfe MS, Selkoe DJ. Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin. J Biol Chem. 2003 Sep 26;278(39):37213-22. Epub 2003 Jul 11. PubMed PMID: 12857757.


Baulac S, LaVoie MJ, Kimberly WT, Strahle J, Wolfe MS, Selkoe DJ, Xia W. Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates. Neurobiol Dis. 2003 Nov;14(2):194-204. PubMed PMID: 14572442.


Kimberly WT, Wolfe MS. Identity and function of gamma-secretase. J Neurosci Res. 2003 Nov 1;74(3):353-60. Review. PubMed PMID: 14598311.


Konopka G, Bonni A. Signaling pathways regulating gliomagenesis. Curr Mol Med. 2003 Feb;3(1):73-84. Review. PubMed PMID: 12558076.


Cannon CL, Kowalski MP, Stopak KS, Pier GB. Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol. 2003 Aug;29(2):188-97. PMID: 12878584


Kaufmann C, Yoshida T, Perotti EA, Landhuis E, Wu P, Georgopoulos K. A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis. EMBO J. 2003 May 1;22(9):2211-23. PubMed PMID: 12727887; PubMed Central PMCID: PMC156063.


Ansel KM, Lee DU, Rao A. An epigenetic view of helper T cell differentiation. Nat Immunol. 2003 Jul;4(7):616-23. Review. PubMed PMID: 12830136.


Lee DU, Avni O, Chen L, Rao A. A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison. J Biol Chem. 2004 Feb 6;279(6):4802-10. Epub 2003 Nov 8. PubMed PMID: 14607827.


Shalizi A, Lehtinen M, Gaudilliere B, Donovan N, Han J, Konishi Y, Bonni A.
Characterization of a neurotrophin signaling mechanism that mediates neuron survival in a temporally specific pattern. J Neurosci. 2003 Aug
13;23(19):7326-36. PubMed PMID: 12917366.


Major DE, Rodman HR, Libedinsky C, Karten HJ. Pattern of retinal projections in the California ground squirrel (Spermophilus beecheyi): anterograde tracing study using cholera toxin. J Comp Neurol. 2003 Aug 25;463(3):317-40. PubMed PMID: 12820165.


Kircher MF, Allport JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R. In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors. Cancer Res. 2003 Oct 15;63(20):6838-46.


Grabie N, Delfs MW, Westrich JR, Love VA, Stavrakis G, Ahmad F, Seidman CE, Seidman JG, Lichtman AH. IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis. J Clin Invest. 2003 Mar;111(5):671-80. PubMed PMID: 12618521; PubMed Central PMCID: PMC151896.


Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH. T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7749-54. Epub 2003 Jun 11. PubMed PMID: 12802010; PubMed Central PMCID: PMC164659.


Llewellyn-Smith IJ, Martin CL, Marcus JN, Yanagisawa M, Minson JB, Scammell TE. Orexin-immunoreactive inputs to rat sympathetic preganglionic neurons. Neurosci Lett. 2003 Nov 13;351(2):115-9. PubMed PMID: 14583395.


Willie JT, Chemelli RM, Sinton CM, Tokita S, Williams SC, Kisanuki YY, Marcus JN, Lee C, Elmquist JK, Kohlmeier KA, Leonard CS, Richardson JA, Hammer RE, Yanagisawa M. Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron. 2003 Jun 5;38(5):715-30. PubMed PMID: 12797957.


Elmquist JK, Marcus JN. Rethinking the central causes of diabetes. Nat Med. 2003 Jun;9(6):645-7. PubMed PMID: 12778157.


Martin CH, Aifantis I, Scimone ML, von Andrian UH, Reizis B, von Boehmer H, Gounari F. Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat Immunol. 2003 Sep;4(9):866-73. Epub 2003 Aug 17. PubMed PMID: 12925850.


Elkin SK, Matthews AG, Oettinger MA. The C-terminal portion of RAG2 protects against transposition in vitro. EMBO J. 2003 Apr 15;22(8):1931-8. PubMed PMID: 12682025; PubMed Central PMCID: PMC154476.


Montalbano A, Ogwaro KM, Tang A, Matthews AG, Larijani M, Oettinger MA, Feeney AJ. V(D)J recombination frequencies can be profoundly affected by changes in the spacer sequence. J Immunol. 2003 Nov 15;171(10):5296-304. PubMed PMID: 14607931.


Du J, Miller AJ, Widlund HR, Horstmann MA, Ramaswamy S, Fisher DE. MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma. Am J Pathol. 2003 Jul;163(1):333-43. PMID: 12819038 PMCID: PMC1868174 read article


Gupta A, Sanada K, Miyamoto DT, Rovelstad S, Nadarajah B, Pearlman AL, Brunstrom J, Tsai LH. Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration. Nat Neurosci. 2003 Dec;6(12):1284-91. Epub 2003 Nov 9. PMID: 14608361


Miyamoto DT, Perlman ZE, Mitchison TJ, Shirasu-Hiza M. Dynamics of the mitotic spindle--potential therapeutic targets. Prog Cell Cycle Res. 2003;5:349-60. PMID: 14593729


Gross JD, Moerke NJ, von der Haar T, Lugovskoy AA, Sachs AB, McCarthy JE, Wagner G. Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell. 2003 Dec 12;115(6):739-50. PMID: 14675538


Moran ST, Haider K, Ow Y, Milton P, Chen L, Pillai S. Protein kinase C-associated kinase can activate NFkappaB in both a kinase-dependent and a kinase-independent manner. J Biol Chem. 2003. Jun 13;278(24):21526-33. PMID:12676934.


Cariappa A, Chen L, Haider K, Tang M, Nebelitskiy E, Moran ST, Pillai S. A catalytically inactive form of protein kinase C-associated kinase/receptor interacting protein 4, a protein kinase C beta-associated kinase that mediates NF-kappa B activation, interferes with early B cell development. J Immunol. 2003. Aug 15;171(4):1875-80. PMID:12902489.


Ng HH, Ciccone DN, Morshead KB, Oettinger MA, Struhl K. Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1820-5. Epub 2003 Feb 6. PubMed PMID: 12574507; PubMed Central PMCID: PMC149917.


Morshead KB, Ciccone DN, Taverna SD, Allis CD, Oettinger MA. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11577-82. Epub 2003 Sep 19. PubMed PMID: 14500909; PubMed Central PMCID: PMC208800.


Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 2003 Oct 23;425(6960):851-6. Epub 2003 Sep 14. PubMed PMID: 14520413.


Olveczky BP, Baccus SA, Meister M. Segregation of object and background motion in the retina. Nature. 2003 May 22;423(6938):401-8. Epub 2003 May 11. PubMed PMID: 12754524.


Smallwood PM, Olveczky BP, Williams GL, Jacobs GH, Reese BE, Meister M, Nathans J. Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11706-11. Epub 2003 Sep 19. PubMed PMID: 14500905; PubMed Central PMCID: PMC208822.


Tao J, Hu S, Pacholec M, Walsh CT. Synthesis of proposed oxidation-cyclization-methylation intermediates of the coumarin antibiotic biosynthetic pathway. Org Lett. 2003 Sep 4;5(18):3233-6. PMID: 12943395


Patten BA, Peyrin JM, Weinmaster G, Corfas G. Sequential signaling through Notch1 and erbB receptors mediates radial glia differentiation. J Neurosci. 2003 Jul 9;23(14):6132-40. PMID: 12853432.


Radosevich M, Ono SJ. Novel mechanisms of class II major histocompatibility complex gene regulation. Immunol Res. 2003;27(1):85-106. Review. PMID: 12637770.


Lleó A, Berezovska O, Ramdya P, Fukumoto H, Raju S, Shah T, Hyman BT. Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression. J Biol Chem. 2003 Nov 28;278(48):47370-5. Epub 2003 Sep 5. PubMed PMID: 12960155.


Berezovska O, Ramdya P, Skoch J, Wolfe MS, Bacskai BJ, Hyman BT. Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging. J Neurosci. 2003 Jun 1;23(11):4560-6. PubMed PMID: 12805296.


Ramdya P, Skoch J, Bacskai BJ, Hyman BT, Berezovska O. Activated Notch1 associates with a presenilin-1/gamma-secretase docking site. J Neurochem. 2003 Nov;87(4):843-50. PubMed PMID: 14622115.


Donnadieu E, Jouvin MH, Rana S, Moffatt MF, Mockford EH, Cookson WO, Kinet JP. Competing functions encoded in the allergy-associated F(c)epsilon RI beta gene. Immunity. 2003 May;18(5):665-74. PMID: 12753743.


Miura-Shimura Y, Duan L, Rao NL, Reddi AL, Shimura H, Rottapel R, Druker BJ, Tsygankov A, Band V, Band H. Cbl-mediated ubiquitinylation and negative regulation of Vav. J Biol Chem. 2003 Oct 3;278(40):38495-504. Epub 2003 Jul 24. PubMed PMID: 12881521.


Awatramani R, Soriano P, Rodriguez C, Mai JJ, Dymecki SM. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat Genet. 2003 Sep;35(1):70-5. Epub 2003 Aug 17. PubMed PMID: 12923530.


Rooney S, Alt FW, Lombard D, Whitlow S, Eckersdorff M, Fleming J, Fugmann S, Ferguson DO, Schatz DG, Sekiguchi J. Defective DNA repair and increased genomic instability in Artemis-deficient murine cells. J Exp Med. 2003 Mar 3;197(5):553-65. PMID: 12615897.


Sánchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, Sabatos CA, Manlongat N, Bender O, Kamradt T, Kuchroo VK, Gutiérrez-Ramos JC, Coyle AJ, Strom TB. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol. 2003 Nov;4(11):1093-101. Epub 2003 Oct 12. PubMed PMID: 14556005.


Sabatos CA, Chakravarti S, Cha E, Schubart A, Sánchez-Fueyo A, Zheng XX, Coyle AJ, Strom TB, Freeman GJ, Kuchroo VK. Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol. 2003 Nov;4(11):1102-10. Epub 2003 Oct 12. PubMed PMID: 14556006.


Samuels BA, Tsai LH. Cdk5 is a dynamo at the synapse. Nat Cell Biol. 2003 Aug;5(8):689-90. PubMed PMID: 12894171.


Xie Z, Sanada K, Samuels BA, Shih H, Tsai LH. Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Cell. 2003 Aug 22;114(4):469-82. PubMed PMID: 12941275.


Martin CH, Aifantis I, Scimone ML, von Andrian UH, Reizis B, von Boehmer H, Gounari F. Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat Immunol. 2003 Sep;4(9):866-73. Epub 2003 Aug 17. PubMed PMID: 12925850.


Soler-Llavina GJ, Holmgren M, Swartz KJ. Defining the conductance of the closed state in a voltage-gated K+ channel. Neuron. 2003 Apr 10;38(1):61-7. PubMed PMID: 12691664.


Allan DW, St Pierre SE, Miguel-Aliaga I, Thor S. Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code. Cell. 2003 Apr 4;113(1):73-86. PubMed PMID: 12679036.


Stanford JS, Lieberman SL, Wong VL, Ruderman JV. Regulation of the G2/M transition in oocytes of xenopus tropicalis. Dev Biol. 2003 Aug 15;260(2):438-48. PMID: 12921744


Stolt PC, Jeon H, Song HK, Herz J, Eck MJ, Blacklow SC. Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes. Structure. 2003 May;11(5):569-79. PMID: 2737822


Fragoso R, Ren D, Zhang X, Su MW, Burakoff SJ, Jin YJ. Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. J Immunol. 2003 Jan 15;170(2):913-21. PMID: 12517957.


Sullivan BM, Juedes A, Szabo SJ, von Herrath M, Glimcher LH. Antigen-driven effector CD8 T cell function regulated by T-bet. PNAS 100(26):15818-23, 2003.


INVITED PUBLICATIONS (non-peer reviewed): Szabo SJ, Sullivan BM, Peng SL, Glimcher LH. Molecular mechanisms regulating Th1 immune responses. Annnu. Rev. Immunol. 21:713-58, 2003.


Thomas SM, Zeng Q, Dyer KF, Suscovich TJ, Kanter PM, Whalen JD, Watkins SF, Grandis JR. Tissue distribution of liposome-mediated epidermal growth factor receptor antisense gene therapy. Cancer Gene Ther. 2003 Jul;10(7):518-28. PMID: 12833132


Field SJ, Madson N, Kerr M, Galbraith K, Kennedy C, Tahiliani M, Cantley L. Functions at the Cleavage Furrow During Cytokinesis. Current Biology (2003) 15 (15): 1407-12.


Taylor TJ, McNamee EE, Day C, Knipe DM. Herpes simplex virus replication compartments can form by coalescence of smaller compartments. Virology. 2003 May 10;309(2):232-47. PMID: 12758171


Taylor TJ, Knipe DM. C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization. Virology. 2003 May 10;309(2):219-31. PMID: 12758170


Thomas SY, Hou R, Boyson JE, Means TK, Hess C, Olson DP, Strominger JL, Brenner MB, Gumperz JE, Wilson SB, Luster AD. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. J Immunol. 2003 Sep 1;171(5):2571-80. PMID: 12928408


Tran H, Brunet A, Griffith EC, Greenberg ME. The many forks in FOXO's road.
Sci STKE. 2003 Mar 4;2003(172):RE5. Review. PubMed PMID: 12621150.


Chiara DC, Trinidad JC, Wang D, Ziebell MR, Sullivan D, Cohen JB. Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist. Biochemistry. 2003 Jan 21;42(2):271-83. PubMed PMID: 12525154.


Tsao DY, Conway BR, Livingstone MS. Receptive fields of disparity-tuned simple cells in macaque V1. Neuron. 2003 Apr 10;38(1):103-14. PubMed PMID: 12691668.


Tsao DY, Vanduffel W, Sasaki Y, Fize D, Knutsen TA, Mandeville JB, Wald LL, Dale AM, Rosen BR, Van Essen DC, Livingstone MS, Orban GA, Tootell RB. Stereopsis activates V3A and caudal intraparietal areas in macaques and humans. Neuron. 2003 Jul 31;39(3):555-68. PubMed PMID: 12895427.


Tsao DY, Freiwald WA, Knutsen TA, Mandeville JB, Tootell RB. Faces and objects in macaque cerebral cortex. Nat Neurosci. 2003 Sep;6(9):989-95. PubMed PMID: 12925854.


Berzins SP, Venanzi ES, Benoist C, Mathis D. T-cell compartments of prediabetic NOD mice. Diabetes. 2003 Feb;52(2):327-34. PubMed PMID: 12540604.


Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J. The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell. 2003 Jul 11;114(1):99-111. PubMed PMID: 12859901.


Chiara DC, Trinidad JC, Wang D, Ziebell MR, Sullivan D, Cohen JB. Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist. Biochemistry. 2003 Jan 21;42(2):271-83. PubMed PMID: 12525154.


He XL, Bazan JF, McDermott G, Park JB, Wang K, Tessier-Lavigne M, He Z, Garcia KC. Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron. 2003 Apr 24;38(2):177-85. PubMed PMID: 12718853.


McAlpine MC, Friedman RS, Jin S, Lin K, Wang WU, Lieber CM, High-Performance Nanowire Electronics and Photonics on Glass and Plastic Substrates. Nano Lett. 2003. 3, 1531-1535.


Cui Y, Zhong Z, Wang D, Wang WU, Lieber CM. High Performance Silicon Nanowire Field Effect Transistors. Nano Lett. 2003. 3, 149-152.


Kramer A, Yang FC, Snodgrass P, Li X, Scammell TE, Davis FC, Weitz CJ.
Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor
signalling. Novartis Found Symp. 2003;253:250-62; discussion 102-9, 263-6, 281-4. PubMed PMID: 14712926.


Yiu G, He Z. Signaling mechanisms of the myelin inhibitors of axon regeneration. Curr Opin Neurobiol. 2003 Oct;13(5):545-51. PMID: 14630216.


Teillon SM, Yiu G, Walsh CA. Reelin is expressed in the accessory olfactory system, but is not a guidance cue for vomeronasal axons. Brain Res Dev Brain Res. 2003 Feb 16;140(2):303-7. PMID: 12586436.


Tietjen I, Rihel JM, Cao Y, Koentges G, Zakhary L, Dulac C. Single-cell transcriptional analysis of neuronal progenitors. Neuron. 2003 Apr 24;38(2):161-75. PubMed PMID: 12718852.


top

2002


Altevogt BM, Kleopa KA, Postma FR, Scherer SS, Paul DL. Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems. J Neurosci. 2002 Aug 1;22(15):6458-70. PubMed PMID: 12151525.


Blair NT, Bean BP. Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons. J Neurosci. 2002 Dec 1;22(23):10277-90. PubMed PMID: 12451128.


Borowski C, Martin C, Gounari F, Haughn L, Aifantis I, Grassi F, von Boehmer H. On the brink of becoming a T cell. Curr Opin Immunol. 2002 Apr;14(2):200-6. Review.


Aifantis I, Borowski C, Gounari F, Lacorazza HD, Nikolich-Zugich J, von Boehmer H. A critical role for the cytoplasmic tail of pTalpha in T lymphocyte development. Nat Immunol. 2002 May;3(5):483-8.


Gozani O, Boyce M, Yoo L, Karuman P, Yuan J. Life and death in paradise. PMID: 12042835


Brittis PA, Lu Q, Flanagan JG. Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell. 2002 Jul 26;110(2):223-35. PubMed PMID: 12150930.


Call ME, Pyrdol J, Wiedmann M, Wucherpfennig KW. The organizing principle in the formation of the T cell receptor-CD3 complex. Cell. 2002 Dec 27;111(7):967-79. PubMed PMID: 12507424.


Carter AG, Vogt KE, Foster KA, Regehr WG. Assessing the role of calcium-induced calcium release in short-term presynaptic plasticity at excitatory central synapses. J Neurosci. 2002 Jan 1;22(1):21-8. PubMed PMID: 11756484.


Kreitzer AC, Carter AG, Regehr WG. Inhibition of interneuron firing extends the spread of endocannabinoid signaling in the cerebellum. Neuron. 2002 May 30;34(5):787-96. PubMed PMID: 12062024.


Carter AG, Regehr WG. Quantal events shape cerebellar interneuron firing. Nat Neurosci. 2002 Dec;5(12):1309-18. PubMed PMID: 12411959.


Borghesani PR, Peyrin JM, Klein R, Rubin J, Carter AR, Schwartz PM, Luster A, Corfas G, Segal RA. BDNF stimulates migration of cerebellar granule cells. Development. 2002 Mar;129(6):1435-42. PubMed PMID: 11880352.


Carter AR, Chen C, Schwartz PM, Segal RA. Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. J Neurosci. 2002 Feb 15;22(4):1316-27. PubMed PMID: 11850459.


Fricker-Gates RA, Shin JJ, Tai CC, Catapano LA, Macklis JD. Late-stage immature neocortical neurons reconstruct interhemispheric connections and form synaptic contacts with increased efficiency in adult mouse cortex undergoing targeted neurodegeneration. J Neurosci. 2002 May 15;22(10):4045-56. PubMed PMID: 12019324.


Catapano LA, Magavi SS, Macklis JD. Neuroanatomical tracing of neuronal projections with Fluoro-Gold. Methods Mol Biol. 2002;198:299-304. PubMed PMID: 11951632.


Chackerian AA, Alt JM, Perera TV, Dascher CC, Behar SM. Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity. Infect Immun. 2002 Aug;70(8):4501-9. PubMed PMID: 12117962; PubMed Central PMCID: PMC128141.


Chackerian A, Alt J, Perera V, Behar SM. Activation of NKT cells protects mice from tuberculosis. Infect Immun. 2002 Nov;70(11):6302-9. PubMed PMID: 12379709; PubMed Central PMCID: PMC130331.


Chae TH, Allen KM, Davisson MT, Sweet HO, Walsh CA. Mapping of the mouse hyh gene to a YAC/BAC contig on proximal Chromosome 7. Mamm Genome. 2002 May;13(5):239-44. PubMed PMID: 12016511.


Froy O, Chang DC, Reppert SM. Redox potential: differential roles in dCRY and mCRY1 functions. Curr Biol. 2002 Jan 22;12(2):147-52. PubMed PMID: 11818067.


Ye H, Arron JR, Lamothe B, Cirilli M, Kobayashi T, Shevde NK, Segal D, Dzivenu OK, Vologodskaia M, Yim M, Du K, Singh S, Pike JW, Darnay BG, Choi Y, Wu H. Distinct molecular mechanism for initiating TRAF6 signalling. Nature. 2002 Jul 25;418(6896):443-7. PubMed PMID: 12140561.


Rubin JB, Choi Y, Segal RA. Cerebellar proteoglycans regulate sonic hedgehog responses during development. Development. 2002 May;129 9):2223-32. PubMed PMID: 11959830.


Saper CB, Chou TC, Elmquist JK. The need to feed: homeostatic and hedonic control of eating. Neuron. 2002 Oct 10;36(2):199-211. Review. PubMed PMID: 12383777.


Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, Monroe BC, Ciccone DN, Yan C, Vlasakova K, Livingston DM, Ferguson DO, Scully R, Alt FW. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8173-8. Epub 2002 May 28. PubMed PMID: 12034884; PubMed Central PMCID: PMC123040.


Claypool SM, Dickinson BL, Yoshida M, Lencer WI, Blumberg RS. Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulin. J. Biol. Chem. 2002 Aug 2; 277(31):28038-50. PMID: 12023961.


Harker N, Naito T, Cortes M, Hostert A, Hirschberg S, Tolaini M, Roderick K, Georgopoulos K, Kioussis D. The CD8alpha gene locus is regulated by the Ikaros family of proteins. Mol Cell. 2002 Dec;10(6):1403-15. PubMed PMID: 12504015.


Lauer GM, Ouchi K, Chung RT, Nguyen TN, Day CL, Purkis DR, Reiser M, Kim AY, Lucas M, Klenerman P, Walker BD. Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities. J Virol. 2002 Jun;76(12):6104-13. PMID: 12021343 PMCID: PMC136241 read article


Lauer GM, Nguyen TN, Day CL, Robbins GK, Flynn T, McGowan K, Rosenberg ES, Lucas M, Klenerman P, Chung RT, Walker BD. Human immunodeficiency virus type 1-hepatitis C virus coinfection: intraindividual comparison of cellular immune responses against two persistent viruses. J Virol. 2002 Mar;76(6):2817-26. PMID: 11861849 PMCID: PMC135971 read article


Landisman CE, Long MA, Beierlein M, Deans MR, Paul DL, Connors BW. Electrical synapses in the thalamic reticular nucleus. J Neurosci. 2002 Feb 1;22(3):1002-9. PubMed PMID: 11826128.


Deans MR, Volgyi B, Goodenough DA, Bloomfield SA, Paul DL. Connexin36 is
essential for transmission of rod-mediated visual signals in the mammalian
retina. Neuron. 2002 Nov 14;36(4):703-12. PubMed PMID: 12441058; PubMed Central PMCID: PMC2834592.


Long MA, Deans MR, Paul DL, Connors BW. Rhythmicity without synchrony in the electrically uncoupled inferior olive. J Neurosci. 2002 Dec 15;22(24):10898-905. PubMed PMID: 12486184; PubMed Central PMCID: PMC2834587.


Desai BN, Myers BR, Schreiber SL. FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4319-24. PubMed PMID: 11930000; PubMed Central PMCID: PMC123646.


Corbo JC, Deuel TA, Long JM, LaPorte P, Tsai E, Wynshaw-Boris A, Walsh CA. Doublecortin is required in mice for lamination of the hippocampus but not the neocortex. J Neurosci. 2002 Sep 1;22(17):7548-57. PubMed PMID: 12196578.


Rao N, Miyake S, Reddi AL, Douillard P, Ghosh AK, Dodge IL, Zhou P, Fernandes ND, Band H. Negative regulation of Lck by Cbl ubiquitin ligase. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3794-9. PubMed PMID: 11904433; PubMed Central PMCID: PMC122603.


Rao N, Dodge I, Band H. The Cbl family of ubiquitin ligases: critical negative regulators of tyrosine kinase signaling in the immune system. J Leukoc Biol. 2002 May;71(5):753-63. Review. PubMed PMID: 11994499.


Dascher CC, Hiromatsu K, Xiong X, Sugita M, Buhlmann JE, Dodge IL, Lee SY, Roura-Mir C, Watts GF, Roy CJ, Behar SM, Clemens DL, Porcelli SA, Brenner MB. Conservation of CD1 intracellular trafficking patterns between mammalian species. J Immunol. 2002 Dec 15;169(12):6951-8. PubMed PMID: 12471129.


Du J, Fisher DE. Identification of Aim-1 as the underwhite mouse mutant and its transcriptional regulation by MITF. J Biol Chem. 2002 Jan 4;277(1):402-6. Epub 2001 Nov 7. PMID: 11700328


McGill GG, Horstmann M, Widlund HR, Du J, Motyckova G, Nishimura EK, Lin YL, Ramaswamy S, Avery W, Ding HF, Jordan SA, Jackson IJ, Korsmeyer SJ, Golub TR, Fisher DE. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. Cell. 2002 Jun 14;109(6):707-18. PMID: 2086670


Baksh S, Widlund HR, Frazer-Abel AA, Du J, Fosmire S, Fisher DE, DeCaprio JA, Modiano JF, Burakoff SJ. NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Mol Cell. 2002 Nov;10(5):1071-81. PMID: 12453415


Dudley DD, Manis JP, Zarrin AA, Kaylor L, Tian M, Alt FW. Internal IgH class switch region deletions are position-independent and enhanced by AID expression. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9984-9. Epub 2002 Jul 11. PMID: 12114543.


Wills Z, Emerson M, Rusch J, Bikoff J, Baum B, Perrimon N, Van Vactor D. A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron. 2002 Nov 14;36(4):611-22. PubMed PMID: 12441051.


Carter AG, Vogt KE, Foster KA, Regehr WG. Assessing the role of calcium-induced calcium release in short-term presynaptic plasticity at excitatory central synapses. J Neurosci. 2002 Jan 1;22(1):21-8. PubMed PMID: 11756484.


Foster KA, Kreitzer AC, Regehr WG. Interaction of postsynaptic receptor saturation with presynaptic mechanisms produces a reliable synapse. Neuron. 2002 Dec 19;36(6):1115-26. PubMed PMID: 12495626.


Halamay KE, Kirkman RL, Sun L, Yamada A, Fragoso RC, Shimizu K, Mitchell RN, McKay DB. CD8 T cells are sufficient to mediate allorecognition and allograft rejection. Cell Immunol, 216(1-2): 6-14. 2002.


Furman MH, Ploegh HL. Lessons from viral manipulation of protein disposal pathways. J Clin Invest. 2002 Oct;110(7):875-9. Review. PubMed PMID: 12370262; PubMed Central PMCID: PMC151163.


Furman MH, Dey N, Tortorella D, Ploegh HL. The human cytomegalovirus US10 gene product delays trafficking of major histocompatibility complex class I molecules. J Virol. 2002 Nov;76(22):11753-6. PubMed PMID: 12388737; PubMed Central PMCID: PMC136774.


Vugmeyster Y, Borodovsky A, Maurice MM, Maehr R, Furman MH, Ploegh HL. The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP). Mol Immunol. 2002 Nov;39(7-8):431-41. PubMed PMID: 12413694.


Chou TC, Bjorkum AA, Gaus SE, Lu J, Scammell TE, Saper CB. Afferents to the ventrolateral preoptic nucleus. J Neurosci. 2002 Feb 1;22(3):977-90. PubMed PMID: 11826126.


Chou TC, Bjorkum AA, Gaus SE, Lu J, Scammell TE, Saper CB. Afferents to the ventrolateral preoptic nucleus. J Neurosci. 2002 Feb 1;22(3):977-90. PubMed PMID: 11826126.


Lu J, Bjorkum AA, Xu M, Gaus SE, Shiromani PJ, Saper CB. Selective activation of the extended ventrolateral preoptic nucleus during rapid eye movement sleep. J Neurosci. 2002 Jun 1;22(11):4568-76. PubMed PMID: 12040064.


Gaus SE, Strecker RE, Tate BA, Parker RA, Saper CB. Ventrolateral preoptic
nucleus contains sleep-active, galaninergic neurons in multiple mammalian
species. Neuroscience. 2002;115(1):285-94. PubMed PMID: 12401341.


Gewurz, BE, Ploegh, HL, Tortorella, D. US2, a Human Cytomegalovirus-Encoded Type I Membrane Protein, Contains a Non-cleavable Amino-terminal Signal Peptide. J. Biological Chemistry. 2002 277(13): 11306-13. PMID: 11790769.


Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem. 2002 Jan 11;277(2):1531-7. Epub 2001 Oct 17. PMID: 11606564


Costigan M, Befort K, Karchewski L, Griffin RS, D'Urso D, Allchorne A, Sitarski J, Mannion JW, Pratt RE, Woolf CJ. Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci. 2002 Oct 25;3:16. Epub 2002 Oct 25. PubMed PMID: 12401135; PubMed Central PMCID: PMC139981.


Renger JJ, Hartman KN, Tsuchimoto Y, Yokoi M, Nakanishi S, Hensch TK. Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):1041-6. PubMed PMID: 11805343; PubMed Central PMCID: PMC117426.


Heerssen HM, Segal RA. Location, location, location: a spatial view of neurotrophin signal transduction. Trends Neurosci. 2002 Mar;25(3):160-5. Review. PubMed PMID: 11852149.


Koipally J, Heller EJ, Seavitt JR, Georgopoulos K. Unconventional potentiation of gene expression by Ikaros. J Biol Chem. 2002 Apr 12;277(15):13007-15. Epub 2002 Jan 17. PMID: 11799125


Barouch DH, Santra S, Tenner-Racz K, Racz P, Kuroda MJ, Schmitz JE, Jackson SS, Lifton MA, Freed DC, Perry HC, Davies ME, Shiver JW, Letvin NL. Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. J Immunol. 2002 Jan 15;168(2):562-8. PubMed PMID: 11777947.


Sakata Y, Kamei CN, Nakagami H, Bronson R, Liao JK, Chin MT. Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16197-202. Epub 2002 Nov 26. PubMed PMID: 12454287; PubMed Central PMCID: PMC138588.


Esler WP, Kimberly WT, Ostaszewski BL, Ye W, Diehl TS, Selkoe DJ, Wolfe MS. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2720-5. Epub 2002 Feb 26. PubMed PMID: 11867728; PubMed Central PMCID: PMC122414.


Esler WP, Das C, Campbell WA, Kimberly WT, Kornilova AY, Diehl TS, Ye W, Ostaszewski BL, Xia W, Selkoe DJ, Wolfe MS. Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase. Nat Cell Biol. 2002 May;4(5):E110-1; author reply E111-2. PubMed PMID: 11988746.


Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulation. J Biol Chem. 2002 Sep 20;277(38):35113-7. Epub 2002 Jul 18. PubMed PMID: 12130643.


He Z, Wang KC, Koprivica V, Ming G, Song HJ. Knowing how to navigate: mechanisms of semaphorin signaling in the nervous system. Sci STKE. 2002 Feb 12;2002(119):re1. Review. PubMed PMID: 11842242.


Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, He Z. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature. 2002 Jun 27;417(6892):941-4. Epub 2002 Jun 16. PubMed PMID: 12068310.


Lee DU, Agarwal S, Rao A. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity. 2002 May;16(5):649-60. PubMed PMID: 12049717.


Avni O, Lee D, Macian F, Szabo SJ, Glimcher LH, Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol. 2002 Jul;3(7):643-51. Epub 2002 Jun 10. PubMed PMID: 12055628.


Konishi Y, Lehtinen M, Donovan N, Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell. 2002 May;9(5):1005-16. PubMed PMID: 12049737.


Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Activation of central melanocortin pathways by fenfluramine. Science. 2002 Jul 26;297(5581):609-11. PubMed PMID: 12142539.


Yamamoto H, Lee CE, Marcus JN, Williams TD, Overton JM, Lopez ME, Hollenberg AN, Baggio L, Saper CB, Drucker DJ, Elmquist JK. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest. 2002 Jul;110(1):43-52. PubMed PMID: 12093887; PubMed Central PMCID: PMC151031.


Gounari F, Aifantis I, Martin C, Fehling HJ, Hoeflinger S, Leder P, von Boehmer H, Reizis B. Tracing lymphopoiesis with the aid of a pTalpha-controlled reporter gene. Nat Immunol. 2002 May;3(5):489-96. Epub 2002 Apr 1. PubMed PMID: 11927910.


Mundy CL, Patenge N, Matthews AG, Oettinger MA. Assembly of the RAG1/RAG2 synaptic complex. Mol Cell Biol. 2002 Jan;22(1):69-77. PubMed PMID: 11739723; PubMed Central PMCID: PMC134220.


Meyers JH, Ryu A, Monney L, Nguyen K, Greenfield EA, Freeman GJ, Kuchroo VK. Cutting edge: CD94/NKG2 is expressed on Th1 but not Th2 cells and costimulates Th1 effector functions. J Immunol. 2002 Nov 15;169(10):5382-6. PubMed PMID: 12421909.


McDonald WH, Ohi R, Miyamoto DT, Mitchison TJ, and Yates JR 3rd. Comparison of three directly coupled HPLC MS/MS strategies for identification of proteins from complex mixtures: single-dimensional LC-MS/MS, 2-phase MudPIT, and 3-phase MudPIT. International Journal of Mass Spectrometry. 2002; 219, 245-251.


Pillai S, Moran ST. Tec kinase pathways in lymphocyte development and transformation. Biochim Biophys Acta. 2002 Jun 21;1602(2):162-7. PMID:12020802.


Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature. 2002 Jul 11;418(6894):181-6. Epub 2002 Jun 23. PubMed PMID: 12077604.


Reppas JB, Usrey WM, Reid RC. Saccadic eye movements modulate visual responses in the lateral geniculate nucleus. Neuron. 2002 Aug 29;35(5):961-74. PubMed PMID: 12372289.


Dymecki SM, Rodriguez CI, Awatramani RB. Switching on lineage tracers using site-specific recombination. Methods Mol Biol. 2002;185:309-34. Review. PubMed PMID: 11768998.


Rooney S, Sekiguchi J, Zhu C, Cheng HL, Manis J, Whitlow S, DeVido J, Foy D, Chaudhuri J, Lombard D, Alt FW. Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol Cell. 2002 Dec;10(6):1379-90. PMID: 12504013.


Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S,Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 2002 Jan 31;415(6871):536-41. PubMed PMID: 11823861.


Sauvageot CM, Stiles CD. Molecular mechanisms controlling cortical
gliogenesis. Curr Opin Neurobiol. 2002 Jun;12(3):244-9. Review. PubMed PMID: 12049929.


Solymar DC, Agarwal S, Bassing CH, Alt FW, Rao A. A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity. 2002 Jul;17(1):41-50. PMID: 12150890.


St Pierre SE, Galindo MI, Couso JP, Thor S. Control of Drosophila imaginal disc development by rotund and roughened eye: differentially expressed transcripts of the same gene encoding functionally distinct zinc finger proteins. Development. 2002 Mar;129(5):1273-81. PubMed PMID: 11874922.


Duckworth BC, Weaver JS, Ruderman JV. G2 arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16794-9. Epub 2002 Dec 11. PMID: 12477927 PMCID: PMC139223 read article


Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, Blumberg RS. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med. 2002 May 6;195(9):1129-43. Erratum in: J Exp Med 2002 Jun 3;195(11):1513. PubMed PMID: 11994418; PubMed Central PMCID: PMC2193714.


Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP, Glimcher LH. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295(5553):338-42, 2002.


Taddese A, Bean BP. Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons. Neuron. 2002 Feb 14;33(4):587-600. PubMed PMID: 11856532.


Taylor TJ, Brockman MA, McNamee EE, Knipe DM. Herpes simplex virus. Front Biosci. 2002 Mar 1;7:d752-64. PMID: 11861220


Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, DiStefano PS, Chiang
LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science. 2002 Apr 19;296(5567):530-4. PubMed PMID: 11964479.


Tseng CC, Bruner SD, Kohli RM, Marahiel MA, Walsh CT, Sieber SA. Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase. Biochemistry. 2002 Nov 12;41(45):13350-9. PMID: 12416979


Hoyer KK, French SW, Turner DE, Nguyen MT, Renard M, Malone CS, Knoetig S, Qi CF, Su TT, Cheroutre H, Wall R, Rawlings DJ, Morse HC 3rd, Teitell MA. Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14392-7. Epub 2002 Oct 14. PubMed PMID: 12381789; PubMed Central PMCID: PMC137894.


Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science. 2002 Nov 15;298(5597):1395-401. Epub 2002 Oct 10. PubMed PMID: 12376594.


Caplan D, Vijayan S, Kuperberg G, West C, Waters G, Greve D, Dale AM. Vascular responses to syntactic processing: event-related fMRI study of relative clauses. Hum Brain Mapp. 2002 Jan;15(1):26-38. PubMed PMID: 11747098.


Domeniconi M, Cao Z, Spencer T, Sivasankaran R, Wang K, Nikulina E, Kimura N, Cai H, Deng K, Gao Y, He Z, Filbin M. Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth. Neuron. 2002 Jul 18;35(2):283-90. PubMed PMID: 12160746.


Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, He Z. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature. 2002 Jun 27;417(6892):941-4. Epub 2002 Jun 16. PubMed PMID: 12068310.


Croker BA, Tarlinton DM, Cluse LA, Tuxen AJ, Light A, Yang FC, Williams DA,
Roberts AW. The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes. J Immunol. 2002 Apr 1;168(7):3376-86. PubMed PMID: 11907095.


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2001


Ramarao MK, Bianchetta MJ, Lanken J, Cohen JB. Role of rapsyn
tetratricopeptide repeat and coiled-coil domains in self-association and
nicotinic acetylcholine receptor clustering. J Biol Chem. 2001 Mar
9;276(10):7475-83. Epub 2000 Nov 21. PubMed PMID: 11087759.


Degterev A, Boyce M, Yuan J. The channel of death. J Cell Biol. 2001 Nov 26;155(5):695-8. Epub 2001 Nov 26. PMID: 11724809 PMCID: PMC2150877 read article


Brittis PA, Flanagan JG. Nogo domains and a Nogo receptor: implications for axon regeneration. Neuron. 2001 Apr;30(1):11-4. Review. PubMed PMID: 11343640.


Catapano LA, Arnold MW, Perez FA, Macklis JD. Specific neurotrophic factors support the survival of cortical projection neurons at distinct stages of development. J Neurosci. 2001 Nov 15;21(22):8863-72. PubMed PMID: 11698598.


Chackerian AA, Perera TV, Behar SM. Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis. Infect Immun. 2001 Apr;69(4):2666-74. PubMed PMID: 11254633; PubMed Central PMCID: PMC98205.


Chang DC, Reppert SM. The circadian clocks of mice and men. Neuron. 2001 Mar;29(3):555-8. Review. PubMed PMID: 11301014.


Estabrooke IV, McCarthy MT, Ko E, Chou TC, Chemelli RM, Yanagisawa M, Saper CB, Scammell TE. Fos expression in orexin neurons varies with behavioral state. J Neurosci. 2001 Mar 1;21(5):1656-62. PubMed PMID: 11222656.


Lu J, Zhang YH, Chou TC, Gaus SE, Elmquist JK, Shiromani P, Saper CB. Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. J Neurosci. 2001 Jul 1;21(13):4864-74. PubMed PMID: 11425913.


Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper CB, Scammell TE. Orexin (hypocretin) neurons contain dynorphin. J Neurosci. 2001 Oct 1;21(19):RC168. PubMed PMID: 11567079.


Gooley JJ, Lu J, Chou TC, Scammell TE, Saper CB. Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci. 2001 Dec;4(12):1165. PubMed PMID: 11713469.


Saper CB, Chou TC, Scammell TE. The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci. 2001 Dec;24(12):726-31. Review. PubMed PMID: 11718878.


Schweitzer R, Chyung JH, Murtaugh LC, Brent AE, Rosen V, Olson EN, Lassar A, Tabin CJ. Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments. Development. 2001 Oct;128(19):3855-66. PubMed PMID: 11585810.


Murtaugh LC, Zeng L, Chyung JH, Lassar AB. The chick transcriptional repressor Nkx3.2 acts downstream of Shh to promote BMP-dependent axial chondrogenesis. Dev Cell. 2001 Sep;1(3):411-22. PubMed PMID: 11702952.


Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, Chang S, Hai H, Ahearn IM, Livingston DM, Resnick I, Rosen F, Seemanova E, Jarolim P, DePinho RA, Weaver DT. Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit. Curr Biol. 2001 Jun 26;11(12):962-6. PubMed PMID: 11448772.


Blumberg RS, van de Wal Y, Claypool S, Corazza N, Dickinson B, Nieuwenhuis E, Pitman R, Spiekermann G, Zhu X, Colgan S, Lencer WI. The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function. Acta Odontol. Scand. 2001 Jun; 59(3): 139-44. PMID: 11501882.


Kelley, C., Koipally, J., Cortés, M. and Georgopoulos, K. 2001. Role of Ikaros Proteins in Lymphocyte Development and Function. In: Hematopoiesis, A Developmental Approach, Leonard I. Zon, ed. (Oxford University Press New York, NY).


Day CL, Shea AK, Altfeld MA, Olson DP, Buchbinder SP, Hecht FM, Rosenberg ES, Walker BD, Kalams SA. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J Virol. 2001 Jul;75(14):6279-91. PMID: 11413294 PMCID: PMC114350  read article


Deans MR, Gibson JR, Sellitto C, Connors BW, Paul DL. Synchronous activity of inhibitory networks in neocortex requires electrical synapses containing
connexin36. Neuron. 2001 Aug 16;31(3):477-85. PubMed PMID: 11516403.


Deans MR, Paul DL. Mouse horizontal cells do not express connexin26 or
connexin36. Cell Commun Adhes. 2001;8(4-6):361-6. PubMed PMID: 12064619; PubMed Central PMCID: PMC2834531.


Nghiem P, Park PK, Kim Ys YS, Desai BN, Schreiber SL. ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint. J BiolChem. 2002 Feb 8;277(6):4428-34. Epub 2001 Nov 15. PubMed PMID: 11711532.


Wong DK, Dudley DD, Dohrenwend PB, Lauer GM, Chung RT, Thomas DL, Walker BD. Detection of diverse hepatitis C virus (HCV)-specific cytotoxic T lymphocytes in peripheral blood of infected persons by screening for responses to all translated proteins of HCV. J Virol. 2001 Feb;75(3):1229-35. PMID: 11152496.


Chiu HT, Hubbard BK, Shah AN, Eide J, Fredenburg RA, Walsh CT, Khosla C. Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8548-53. Epub 2001 Jul 10. PMID: 11447274 PMCID: PMC37473 read article


Furman MH, Ploegh HL, Tortorella D. Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules. J Biol Chem. 2002 Feb 1;277(5):3258-67. Epub 2001 Nov 20. PubMed PMID: 11717308.


Gewurz, BE, Wang, EW, Tortorella, D, Schust, DJ, Ploegh, HL. The Human Cytomegalovirus US2 Endoplasmic Reticulum-lumenal Domain Dictates Association with Major Histocompatibility Complex Class I in a Locus-specific Manner. J. Virology. 2001 75(11): 5197-204. PMID: 11333901.


Gewurz, BE, Gaudet, R, Tortorella, D, Wang, EW, Ploegh, HL. Virus Immune-evasion: a Structural Perspective. Current Opinion in Immunology. 2001 13(4):442-50. PMID 11498300.


Gewurz, BE, Gaudet, R, Tortorella, D, Wang, EW, Ploegh, HL, Wiley, DC. Antigen Presentation Subverted: Structure of the Human Cytomegalovirus Protein US2 Bound to the Class I Molecule HLA-A2. Proc Natl Acad Sci USA. 2001 98(12): 6794-6799. PMID: 11391001.


Gooley JJ, Lu J, Chou TC, Scammell TE, Saper CB. Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci. 2001 Dec;4(12):1165. PubMed PMID: 11713469.


Watson FL, Heerssen HM, Bhattacharyya A, Klesse L, Lin MZ, Segal RA. Neurotrophins use the Erk5 pathway to mediate a retrograde survival response. Nat Neurosci. 2001 Oct;4(10):981-8. Erratum in: Nat Neurosci 2002 Oct;5(10):1017. PubMed PMID: 11544482.


LaBonte ML, Hershberger KL, Korber B, Letvin NL. The KIR and CD94/NKG2 families of molecules in the rhesus monkey. Immunol Rev. 2001 Oct;183:25-40. PMID: 11782245


Hershberger KL, Shyam R, Miura A, Letvin NL. Diversity of the killer cell Ig-like receptors of rhesus monkeys. J Immunol. 2001 Apr 1;166(7):4380-90. PMID: 11254692


Kane LP, Andres PG, Howland KC, Abbas AK, Weiss A. Akt provides the CD28 costimulatory signal for the up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nat Immunol. 2001 Jan;2(1):37-44.


Staats HF, Bradney CP, Gwinn WM, Jackson SS, Sempowski GD, Liao HX, Letvin NL, Haynes BF. Cytokine requirements for induction of systemic and mucosal CTL after nasal immunization. J Immunol. 2001 Nov 1;167(9):5386-94. PubMed PMID: 11673557.


Sun J, Kamei CN, Layne MD, Jain MK, Liao JK, Lee ME, Chin MT. Regulation of myogenic terminal differentiation by the hairy-related transcription factor CHF2. J Biol Chem. 2001 May 25;276(21):18591-6. Epub 2001 Feb 22. PubMed PMID: 11279181.


Volles MJ, Lee SJ, Rochet JC, Shtilerman MD, Ding TT, Kessler JC, Lansbury PT Jr. Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry. 2001 Jul 3;40(26):7812-9. PMID: 11425308


Kimberly WT, Zheng JB, Guénette SY, Selkoe DJ. The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner. J Biol Chem. 2001 Oct 26;276(43):40288-92. Epub 2001 Sep 5. PubMed PMID: 11544248.


Ko J, Humbert S, Bronson RT, Takahashi S, Kulkarni AB, Li E, Tsai LH. p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci. 2001 Sep 1;21(17):6758-71. PubMed PMID: 11517264.


Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol. 2001 Oct;3(10):905-12. PubMed PMID: 11584272.


LaBonte ML, Hershberger KL, Korber B, Letvin NL. The KIR and CD94/NKG2 families of molecules in the rhesus monkey. Immunol Rev. 2001 Oct;183:25-40. PMID: 11782245


Marcus JN, Aschkenasi CJ, Lee CE, Chemelli RM, Saper CB, Yanagisawa M, Elmquist JK. Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol. 2001 Jun 18;435(1):6-25. PubMed PMID: 11370008.


Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell. 2001 Feb 9;104(3):365-76. PubMed PMID: 11239394.


Karuman P, Gozani O, Odze RD, Zhou XC, Zhu H, Shaw R, Brien TP, Bozzuto CD, Ooi D, Cantley LC, Yuan J. The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death. Mol Cell. 2001 Jun;7(6):1307-19. PMID: 11430832


Seth KA, Majzoub JA. Repressor element silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) can act as an enhancer as well as a repressor of corticotropin-releasing hormone gene transcription. J Biol Chem. 2001 Apr 27;276(17):13917-23. Epub 2001 Feb 1. PubMed PMID: 11278361.


Fling SP, Sutherland RA, Steele LN, Hess B, D'Orazio SE, Maisonneuve J, Lampe MF, Probst P, Starnbach MN. CD8+ T cells recognize an inclusion membrane-associated protein from the vacuolar pathogen Chlamydia trachomatis. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1160-5. PubMed PMID: 11158611; PubMed Central PMCID: PMC14725.


Su MW, Yu CL, Burakoff SJ, Jin YJ. Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation. J Immunol. 2001 Mar 15;166(6):3975-82. PMID: 11238643.


Lu Q, Sun EE, Klein RS, Flanagan JG. Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 2001 Apr 6;105(1):69-79. PMID: 11301003


Brander C, O'Connor P, Suscovich T, Jones NG, Lee Y, Kedes D, Ganem D, Martin J, Osmond D, Southwood S, Sette A, Walker BD, Scadden DT. Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein. J Infect Dis. 2001 Jul 15;184(2):119-26. Epub 2001 Jun 18. PMID: 11424007


Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol. 2001 Feb;21(3):952-65. PubMed PMID: 11154281; PubMed Central PMCID: PMC86685.


Suo Z, Tseng CC, Walsh CT. Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):99-104. PMID: 11134531 PMCID: PMC14551 read article


Chen H, Tseng CC, Hubbard BK, Walsh CT. Glycopeptide antibiotic biosynthesis: enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14901-6. PMID: 11752437 PMCID: PMC64956 read article


Kramer A, Yang FC, Snodgrass P, Li X, Scammell TE, Davis FC, Weitz CJ.
Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor
signaling. Science. 2001 Dec 21;294(5551):2511-5. PubMed PMID: 11752569.


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2000


Carter AG, Regehr WG. Prolonged synaptic currents and glutamate spillover at the parallel fiber to stellate cell synapse. J Neurosci. 2000 Jun 15;20(12):4423-34. PubMed PMID: 10844011.


Wu X, Ranganathan V, Weisman DS, Heine WF, Ciccone DN, O'Neill TB, Crick KE, Pierce KA, Lane WS, Rathbun G, Livingston DM, Weaver DT. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature. 2000 May 25;405(6785):477-82. PubMed PMID: 10839545.


Melián A, Watts GF, Shamshiev A, De Libero G, Clatworthy A, Vincent M, Brenner MB, Behar S, Niazi K, Modlin RL, Almo S, Ostrov D, Nathenson SG, Porcelli SA. Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs. J Immunol. 2000 Oct 15;165(8):4494-504. PubMed PMID: 11035089.


Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL. Viral subversion of the immune system. Annu Rev Immunol. 2000;18:861-926. Review. PubMed PMID: 10837078.


Furman MH, Ploegh HL, Schust DJ. Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface? Hum Immunol. 2000 Nov;61(11):1169-76. Review. PubMed PMID: 11137223.


McAdam AJ, Farkash EA, Gewurz BE, Sharpe AH. B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus. J. Virology. 2000 74(1): 203-8. PMID: 10590107.


McAdam, AJ, Gewurz BE, Farkash, EA, Sharpe, AH. Either B7 costimulation or IL-2 can elicit generation of primary alloreactive CTL. J. Immunology. 2000 165(6): 3088-93. PMID: 10975820.


Tortorella D, Gewurz BE, Schust DJ, Furman MH, Ploegh HL. Down-regulation of MHC Class I Antigen Presentation by HCMV; Lessons for Tumor Immunology. Immunol. Invest. 2000. 29(2): 97-100. PMID 10854174.


Tortorella, D, Gewurz, BE, Furman, MH, Schust, DJ and Ploegh, HL. Viral Subversion of the Immune System. Ann Rev Immunology. 2000 18: 861-926. PMID 10837078.


Etemad-Moghadam B, Sun Y, Nicholson EK, Fernandes M, Liou K, Gomila R, Lee J, Sodroski J. Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo. J Virol. 2000 May;74(9):4433-40. PMID: 10756060 PMCID: PMC111962 read article


Howland KC, Ausubel LJ, London CA, Abbas AK. The roles of CD28 and CD40 ligand in T cell activation and tolerance. J Immunol. 2000 May 1;164(9):4465-70.


Santra S, Barouch DH, Jackson SS, Kuroda MJ, Schmitz JE, Lifton MA, Sharpe AH, Letvin NL. Functional equivalency of B7-1 and B7-2 for costimulating plasmid DNA vaccine-elicited CTL responses. J Immunol. 2000 Dec 15;165(12):6791-5. PubMed PMID: 11120800.


Kimberly WT, Xia W, Rahmati T, Wolfe MS, Selkoe DJ. The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation. J Biol Chem. 2000 Feb 4;275(5):3173-8. PubMed PMID: 10652302.


Esler WP, Kimberly WT, Ostaszewski BL, Diehl TS, Moore CL, Tsai JY, Rahmati T, Xia W, Selkoe DJ, Wolfe MS. Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1. Nat Cell Biol. 2000 Jul;2(7):428-34. PubMed PMID: 10878808.


Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling. J Neurochem. 2000 Aug;75(2):583-93. PubMed PMID: 10899933.


Xia W, Ray WJ, Ostaszewski BL, Rahmati T, Kimberly WT, Wolfe MS, Zhang J, Goate AM, Selkoe DJ. Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9299-304. PubMed PMID: 10922078; PubMed Central PMCID: PMC16862.


Xia W, Ostaszewski BL, Kimberly WT, Rahmati T, Moore CL, Wolfe MS, Selkoe DJ. FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex. Neurobiol Dis. 2000 Dec;7(6 Pt B):673-81. PubMed PMID: 11114265


Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711. PubMed PMID: 11163260.


Chen Z, Koralov SB, Gendelman M, Carroll MC, Kelsoe G. Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence . J Immunol. 2000. 164(9):4522-32.


Review Article: Chen Z, Koralov SB, Kelsoe G. Regulation of humoral immune responses by CD21/CD35. Immunol Rev. 2000;176:194-204. PMID: 11043778.


LaBonte ML, Levy DB, Letvin NL. Characterization of rhesus monkey CD94/NKG2 family members and identification of novel transmembrane-deleted forms of NKG2-A, B, C, and D. Immunogenetics. 2000 May;51(6):496-9. PMID: 10866118


Lin JW, Ju W, Foster K, Lee SH, Ahmadian G, Wyszynski M, Wang YT, Sheng M. Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization. Nat Neurosci. 2000 Dec;3(12):1282-90. PubMed PMID: 11100149.


Man HY, Lin JW, Ju WH, Ahmadian G, Liu L, Becker LE, Sheng M, Wang YT. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron. 2000 Mar;25(3):649-62. Erratum in: Neuron 2001 Jan;29(1):307. PubMed PMID: 10774732.


Haggarty SJ, Mayer TU, Miyamoto DT, Fathi R, King RW, Mitchison TJ, Schreiber SL. Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis. Chem Biol. 2000 Apr;7(4):275-86. PMID: 10780927


Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell. 2000 Nov;6(5):1037-48. PubMed PMID: 11106743.


Rodriguez CI, Dymecki SM. Origin of the precerebellar system. Neuron. 2000 Sep;27(3):475-86. PubMed PMID: 11055431.


Brander C, Suscovich T, Lee Y, Nguyen PT, O'Connor P, Seebach J, Jones NG, van Gorder M, Walker BD, Scadden DT. Impaired CTL recognition of cells latently infected with Kaposi's sarcoma-associated herpes virus. J Immunol. 2000 Aug 15;165(4):2077-83. PMID: 10925292


Tavazoie SF, Reid RC. Diverse receptive fields in the lateral geniculate nucleus during thalamocortical development. Nat Neurosci. 2000 Jun;3(6):608-16. PubMed PMID: 10816318.


Jones CA, Taylor TJ, Knipe DM. Biological properties of herpes simplex virus 2 replication-defective mutant strains in a murine nasal infection model. Virology. 2000 Dec 5;278(1):137-50. PMID: 11112490


McNamee EE, Taylor TJ, Knipe DM. A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: effects on DNA replication and late gene expression. J Virol. 2000 Nov;74(21):10122-31. PMID: 11024141 PMCID: PMC102051 read article


Trinidad JC, Fischbach GD, Cohen JB. The Agrin/MuSK signaling pathway is spatially segregated from the neuregulin/ErbB receptor signaling pathway at the neuromuscular junction. J Neurosci. 2000 Dec 1;20(23):8762-70. PubMed PMID: 11102484.


Vedantham V, Cannon SC. Rapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channels. Biophys J. 2000 Jun;78(6):2943-58. PubMed PMID: 10827974; PubMed Central PMCID: PMC1300879.


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DMS Student Body

2014-2015 - 655 students

 

Women: 331 (51%)

Men: 324 (49%)

 

Underrepresented Minority: 61 (9%)

 

Domestic: 512 (78%)

International: 143 (22%)

 

PhD: 600 (92%)

MD-PhD: 55 (8%)

 

BIG*: 15 (2%)

BBS: 358 (55%)
Immunology: 72 (11%)

Neuroscience: 123 (19%)

SHBT*: 20 (3%)

Virology: 67 (10%)

 

*These programs became a part of DMS in the Fall 2012. The number of students listed are DMS students only, students that are enrolled before the program became part of DMS are not included.


© 2013 by the President and Fellows of Harvard 
College