Completed Ph.D.s

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993

2014

Arora, Natasha - BBS
Developmental Maturation within the Hematopoietic System
Advisor: George Daley

Atkins, Benjamin - BBS
Inhibition of Cdc42 during mitotic exit is required for cytokinesis in Saccharomyces cerevisiae
Advisor: David Pellman

Bick, Alexander - BBS
At the Heart of the Genome: Rare Genetic Variation, Cardiovascular Disease, and Therapy
Advisor: Jonathan Seidman

Blain, Jonathan - BBS
Non-Enzymatic Copying of Nucleic Acid Templates
Advisor: Jack Szostak

Bonham, Kevin - IMM
Cellular and Biochemical Events in Toll-like Receptor Signaling
Advisor: Jon Kagan

Bowen, Margot - BBS
Applying Next Generation Sequencing to Skeletal Development and Disease
Advisor: Matthew Warman

Brust, Rachael - BBS
A specialized serotonergic neuron subtype transduces chemosensory signals and regulates breathing
Advisor: Susan Dymecki

Carroll, Kelli - BBS
The Role of Estrogen Signaling in the Induction, Specification, and Proliferation of Hematopoietic Stem Cells
Advisor: Trista North

Chan, Ying Leong - BBS
Leveraging genetic association data to investigate the polygenic architecture of human traits and diseases
Advisor: Joel Hirschhorn

Cherry, Anne - BBS
Reprogramming Pediatric Genetic Disorders: Pearson Syndrome, Ring 14 Syndrome, and Fanconi Anemia
Advisor: George Daley

Choi, Youngeun - BBS
Modulation of small RNA silencing by cross-generational signaling in C. elegans
Advisor: Susan Mango

Chu, Yunxiang - NSCI
The Role of Protein Kinase C in Short-Term Synaptic Plasticity
Advisor: Wade Regehr

Cong, Le - BBS
Genome Engineering Technology and Its Application in Mammalian Cells
Advisor: George Church

Durand, Ellen - BBS
Regulation of Hematopoietic Stem Cell Migration and Function
Advisor: Leonard Zon

Dwyer, Daniel - IMM
Effector roles of Granulocytes and B cells during Th2 Inflammation
Advisor: K. Frank Austen

Ellis, Laura - VIR
Investigating the roles of the JC virus agnogene and regulatory region using a naturally occurring, pathogenic viral isolate
Advisor: Igor Koralnik

Fisek, Mehmet - NSCI
Connectivity and computations in higher-order olfactory neurons in Drosophila
Advisor: Rachel Wilson

Ganis, Jared - BBS
Regulators of hemoglobin switching in zebrafish and human models
Advisor: Leonard Zon

Gardner, Matthew - VIR
TARGETING THE CD4- AND CORECEPTOR-BINDING SITES OF THE HIV-1 ENVELOPE GLYCOPROTEIN
Advisor: Michael Farzan

Garnaas, Maija - BBS
The Role of Nuclear Receptor Signaling in Vertebrate Liver Development
Advisor: Wolfram Goessling

Garst Orozco, Jonathan - NSCI
LEARNING-RELATED CHANGES IN THE FUNCTIONAL CONNECTIVITY WITHIN THE ZEBRA FINCH SONG-CONTROL CIRCUIT
Advisor: Bence Ölveczky

Gasser, Jessica - BBS
Serum and Glucocorticoid- Regulated Kinase Signaling in Breast Cancer
Advisor: Alex Toker

Gifford, Casey - BBS
Transcriptional and Epigenetic Dynamics Observed During Lineage Specification of Human Embryonic Stem Cells
Advisor: Alexander Meissner

Goodman, Brian - BBS
Investigating Cytoskeletal Motor Mechanisms using DNA Nanotechnology
Advisor: Samara Reck-Peterson

Guth, Charles - VIR
Contribution of PDZD8 to Stabilization of the Human Immunodeficiency Virus (HIV-1) Capsid
Advisor: Joseph Sodroski

Hall, Jessica - BBS
Thyroid Hormone and Insulin Metabolic Actions on Energy and Glucose Homeostasis
Advisor: Pere Puigserver

Herman, Jonathan - BBS
HALOFUGINONE: A STORY OF HOW TARGET IDENTIFICATION OF AN ANCIENT CHINESE MEDICINE AND MULTI-STEP EVOLUTION INFORMS MALARIA DRUG DISCOVERY
Advisor: Dyann Wirth

Hill, Sarah - BBS
New insights into BRCA1 function and its role in cancer development
Advisor: David Livingston

Ho, Brian - BBS
Characterization of the Antibacterial Activity of the Type VI Secretion System
Advisor: John Mekalanos

Hsu, Cynthia - BBS
In vitro Studies of Myofibers and Their Use in Analyzing the Differential Dynamics and Properties of α-Actinin Isoforms
Advisor: Alan Beggs

Ilter, Didem - BBS
The Role of ERK2 in Regulating Epithelial-Mesenchymal Transition
Advisor: John Blenis

Inniss, Mara - BBS
Tracking Cell Fate with Synthetic Memory and Pulse Detecting Transcriptional Circuits
Advisor: Pamela Silver

Kolodin, Dmitriy - IMM
Dynamics of Tissue-Resident Regulatory T Cell Populations
Advisor: Christophe Benoist

Kung, Johnny - BBS
Genome-wide Analysis of Ctcf-RNA Interactions
Advisor: Jeannie Lee

Lau, Allison - BBS
Characterization of lung tumor-propagating cells reveals a role for CD24 and Yap/Taz in lung cancer progression and metastasis
Advisor: Carla Kim

Lee, Daniel - BBS
Cellular Targets of Propranolol in Infantile Hemangioma
Advisor: Joyce Bischoff

Lehrman, Emily - NSCI
Innate immune molecules direct microglia-mediated developmental synaptic refinement
Advisor: Beth Stevens

Levasseur, Kathryn - BBS
Elucidating the virulence control network in Francisella tularensis
Advisor: Simon Dove

Lim, Teng Ting - BBS
Exploring the genetic landscape of complex diseases using the recessive model
Advisor: Mark Daly

Lin, Youshan Melissa - BBS
The role of Ppargc1αlpha in neuronal survival and myelination in the neocortex
Advisor: Paola Arlotta

Liu, Jue - BBS
Epigenetic shielding: 5-hydroxymethylcytosine and 5-carboxylcytosine modulate UV induction of DNA photoproducts
Advisor: David Fisher

Liu, Wendy - NSCI
Dissecting Olfactory Circuits in Drosophila
Advisor: Rachel Wilson

Loeliger, Erin - BBS
Structure-Function Analysis of the Conserved Histone Chaperone Spt6
Advisor: Fred Winston

Luth, Eric - NSCI
Physiological and Pathological Characterization of Alpha-Synuclein Oligomers
Advisor: Dennis Selkoe

Matreyek, Kenneth - VIR
HIV-1 capsid engages nucleoporin NUP153 to promote viral nuclear entry
Advisor: Alan Engelman

Naxerova, Kamila - BBS
Tracing human cancer evolution with hypermutable DNA
Advisor: Rakesh Jain

Netravali, Ilka - IMM
Elucidation of plasmacytoid dendritic cell development
Advisor: Shiv Pillai

Ng, Shyh Chang - BBS
Regulation of Stem Cell Metabolism by the Lin28/let-7 Axis
Advisor: George Daley

Nizza, Suzanne Josette - BBS
The Role of Dendritic Cell Subsets in Cross-presentation and Stimulation of Homing Marker Expression
Advisor: James Campbell

Olive, Andrew - BBS
Immunity to Chlamydia trachomatis and Host-Pathogen Interactions During Infection
Advisor: Michael Starnbach

Painter, Michio - IMM
Regeneration in the aging peripheral nervous system
Advisor: Clifford Woolf

Quan, Jie - BBS
The Roles of RNA-binding Proteins in the Developing Nervous System
Advisor: John Flanagan

Quinlan, Brian - VIR
Directed Evolution of Peptide Inhibitors of HIV-1 Entry
Advisor: Michael Farzan

Ratanasirintrawoot, Sutheera - BBS
Defining markers and mechanisms of human somatic cell reprogramming
Advisor: George Daley

Ray, Mridula - BBS
Long non-coding RNAs interact with PRC1 to impact Polycomb group protein recruitment and expression of Polycomb regulated genes
Advisor: Robert Kingston

Robinson, Kathleen - BBS
Cutaneous Biology and Endogenous Opioids: How the Skin Modulates Pain and Addiction
Advisor: David Fisher

Rosetti Sciutto, Florencia - IMM
Neutrophil human Fcg Receptor IIA and the b2 integrin Mac-1 cross-talk in autoimmune disease
Advisor: Tanya Mayadas

Rothchild, Alissa - IMM
Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection
Advisor: Samuel Behar

Schafer, Jamie - VIR
Rhesus macaque KIR recognition of MHC class I molecules: Ligand identification and modulation of interaction by SIV peptides
Advisor: David Evans

Sharifnia, Tanaz - BBS
Genetic and Chemical Modifiers of EGFR Dependence in Non-Small Cell Lung Cancer
Advisor: Matthew Meyerson

Stoppel, David - NSCI
Social Behavior and Gene Expression Disturbances in Mouse Models of Angelman Syndrome and Idic15 Autism
Advisor: Matthew Anderson

Teigler, Jeffrey - VIR
Differential Innate Immune Stimulation Elicited by Adenovirus and Poxvirus Vaccine Vectors
Advisor: Dan Barouch

Tepsuporn, Suprawee - IMM
Role of ATM in Suppressing Oncogenic Translocations and Mature B cell Lymphomas
Advisor: Frederick Alt

Thanawala, Monica - NSCI
Control of Neurotransmitter Release Properties by Presynaptic Calcium
Advisor: Wade Regehr

Tseng, Wen - BBS
LYSOSOMAL DESTABILIZATION IN RETINAL PIGMENT EPITHELIAL CELLS ACTIVATES THE NLRP3 INFLAMMASOME AND INDUCES IL-1β SECRETION
Advisor: Patricia D'Amore

Uygur, Aysu - BBS
Evolution of Morphology: Modifications to Size and Pattern
Advisor: Clifford Tabin

Valdez, Cammi - BBS
The Role of Pericyte Loss in Adult Retinal Microvascular Stability: Implications for Diabetic Retinopathy
Advisor: Patricia D'Amore

Vujovic, Nina - NSCI
Functional organization of the circadian timing system
Advisor: Clifford Saper

Wang, Ran - BBS
Optimizing rare variant association studies in theory and practice
Advisor: Joel Hirschhorn

Yanez, Adrienne - BBS
Regulation of microRNA activity by translation initiation factors in melanoma
Advisor: Carl Novina

Yang, Peter - BBS
Central role for Sonic hedgehog-triggered pericytes in hindbrain choroid plexus development
Advisor: Susan Dymecki

2013

Adamson, Brittany - BBS
A genome-wide study of homologous recombination in mammalian cells identifies RBMX, a novel component of the DNA damage response
Advisor: Stephen Elledge

Austin-Tse, Christina - BBS
Sensational propellers: novel protein functions in cilia assembly and motility
Advisor: Iain Drummond

Baca, Sylvan - BBS
The landscape of somatic mutations in primary prostate adenocarcinoma
Advisor: Levi Garraway

Bagchi, Mandrita - BBS
Role of Vascular Endothelial Growth Factor Signaling in Brown Adipocyte Survival, Proliferation and Function
Advisor: Patricia D'Amore

Bialas, Allison - NSCI
Initiating Complement-dependent Synaptic Refinement: Mechanisms of Neuronal C1q Regulation
Advisor: Beth Stevens

Bollman, Brooke - VIR
Role of the Capsid Helix 4-5 Loop in Equine Infectious Anemia Virus Infection
Advisor: Joseph Sodroski

Burrill, Devin - BBS
Tracking cell fate with synthetic memory circuits
Advisor: Pamela Silver

Cai, Xuyu - BBS
Single-Neuron Sequencing to Explore Somatic Genetic Variants in Normal and Pathological Human Brain Development
Advisor: Christopher Walsh

Choi, Eun Young - NSCI
The Organization of Corticostriatal Connectivity in the Human Brain
Advisor: Randy Buckner

Choi, Seungwon - BBS
Regulation of Behavioral Arousal in C.elegans
Advisor: Joshua Kaplan

Christodoulou, Danos - BBS
Methods for comprehensive transcriptome analysis using next-generation sequencing and application in hypertrophic cardiomyopathy
Advisor: Jonathan Seidman

Clark, Erin - BBS
New Mechanisms of Activation by Histone Demethylases in Gene Regulation
Advisor: Yujiang Shi

Clark, Margaret - VIR
Exploring Dengue Virus Entry Through Small Molecule Inhibition and Mutagenesis of the Envelope Protein
Advisor: Priscilla Yang

Daniels, Rachel - BBS
Genomic tools reveal changing Plasmodium falciparum populations
Advisor: Dyann Wirth

Davidowitz, Rachel - BBS
Mechanisms Governing Mesothelial Clearance by Ovarian Cancer Spheroids
Advisor: Joan Brugge

Deering, Raquel - IMM
The ALS-linked gene TDP-43 regulates IFNβ expression through a novel mechanism of 3’ UTR-mediated promoter cis-regulation
Advisor: Nir Hacohen

Dickson, John - BBS
The Role of the Human Tau 3’-Untranslated Region in Regulating Tau Expression
Advisor: Michael Wolfe

Edwards, Amanda - BBS
Dissecting and Targeting the PUMA and OLIG2 Control Points of Tumors of Neuroectodermal Origin with Stapled Peptides
Advisor: Loren Walensky

Eisner, Adriana - NSCI
Phosphatome RNAi Screen Identifies Eya1 as a Positive Regulator of Hedgehog Signal Transduction
Advisor: Rosalind Segal

Er, Ekrem - BBS
Discovering Novel Feedback and Crosstalk Mechanisms in Cellular Signaling Pathways
Advisor: John Blenis

Evrony, Gilad - BBS
Single-cell Sequencing Studies of Somatic Mutation in the Human Brain
Advisor: Christopher Walsh

Fankhauser, Sarah - BBS
Characterization of impaired CD8+ T cell responses to Chlamydia trachomatis
Advisor: Michael Starnbach

Feliu-Mojer, Monica - NSCI
Coupling the small GTPase Rab3 to the Synaptic Vesicle Cycle
Advisor: Joshua Kaplan

Ferrero, David - NSCI
Olfactory control of instinctive behaviors
Advisor: Stephen Liberles

Grady, Joshua - BBS
Adapting Quantitative Protein and Phosphorylation Analyses to a Proteome-Wide Scale
Advisor: Steven Gygi

Hrvatin, Sinisa - BBS
Exploring the use of human pluripotent stem cells to create functional pancreatic β cells
Advisor: Douglas Melton

Ibarra, Yessenia - NSCI
Characterization of human TRPA1 and TRPV1 channels in response to naturally occurring defensive compounds
Advisor: David Clapham

Keskin, Doruk - BBS
Functional Contribution of PDGFRbeta+ Cells in Angiogenesis and Metastatic Breast Cancer
Advisor: Raghu Kalluri

Konieczkowski, David - BBS
Systematic approaches to overcoming limitations of MAPK pathway inhibition in melanoma
Advisor: Levi Garraway

Kostic, Aleksandar - BBS
Deep sequencing and functional analyses identify a role of Fusobacterium species in colorectal tumorigenesis
Advisor: Matthew Meyerson

Kowalko, Johanna - BBS
The genetic basis of behavior in the blind Mexican cavefish, Astyanax mexicanus
Advisor: Clifford Tabin

LeBlanc, Jocelyn - NSCI
Critical period plasticity and sensory function in a neuroligin-3 model of autism
Advisor: Michela Fagiolini

Lee, Mark - IMM
Genomic approaches to dissect innate immune pathways
Advisor: Nir Hacohen

Lim, Hui Jun - VIR
Dynamic regulation of histone lysine methylation via the ubiquitin-proteasome system.
Advisor: Yang Shi

Lohmueller, Jason - BBS
Synthetic Biology Approaches to Engineering Human Cells
Advisor: Pamela Silver

Lopez, Lyle Vincent - BBS
Regulation of Gli proteins by the Hedgehog Signaling Pathway
Advisor: Adrian Salic

Lou, Shan - NSCI
DEVELOPMENT AND FUNCTIONS OF C-LOW-THRESHOLD MECHANORECEPTORS
Advisor: Qiufu Ma

Maeder, Morgan - BBS
Engineered DNA-Binding Proteins for Targeted Genome Editing and Gene Regulation
Advisor: Jae Joung

Malhotra, Deepali - IMM
Insights into the Transcriptional Identities of Lymph Node Stromal Cell Subsets Isolated from Resting and Inflamed Lymph Nodes
Advisor: Shannon Turley

Malik, Athar - NSCI
Genome-wide identification and characterization of stimulus-responsive enhancers in the nervous system
Advisor: Michael Greenberg

Mardinly, Alan - NSCI
Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons
Advisor: Michael Greenberg

McLaughlin, Sara - BBS
Identification and Analysis of a New Tumor and Metastasis Suppressor Gene, RASAL2
Advisor: Karen Cichowski

Mejia, Luis - NSCI
Interaction Proteomics of Autism Spectrum Disorder- and Intellectual Disability-Associated Proteins Identifies A Novel Hap1-Tsc1 Signaling Link That Controls Neuronal mTORC1 Signaling and Pyramidal Neuron Morphogenesis
Advisor: Azad Bonni

Montero Diez, Cristina - BBS
Functional characterization of a bacteriophage-encoded inhibitor of Staphylococcus aureus transcription
Advisor: Ann Hochschild

Moorjani, Priya - BBS
Genetic study of population mixture and its role in human history
Advisor: David Reich

Nedelcu, Daniel - BBS
Smoothened regulation in the Hedgehog signaling pathway
Advisor: Adrian Salic

O'Day, Elizabeth - BBS
Using NMR to identify structural features of Lin28-regulated miRNAs and mRNAs and as a tool for comparing differences in cellular metabolism
Advisor: Judy Lieberman

Orzalli, Megan - VIR
Inhibition of Nuclear DNA Sensing by Herpes Simplex Virus 1
Advisor: David Knipe

Pavlova, Natalya - BBS
A Role for PVRL4-driven Cell-Cell Interactions in Tumorigenesis
Advisor: Stephen Elledge

Quast, Kathleen - NSCI
Functional Development and Plasticity of Parvalbumin Cells in Visual Cortex: Role of Thalamocortical Input
Advisor: Takao Hensch

Reavey, Caitlin - BBS
Analysis of Transcription Activation Distance as a Polygenic Trait in Saccharomyces cerevisiae
Advisor: Fred Winston

Redwine, William - BBS
The Structural Basis for Microtubule Binding and Release by Dynein
Advisor: Andres Leschziner

Rhee, David - BBS
Transcription Factor Networks in Drosophila melanogaster
Advisor: Spyridon Artavanis-Tsakonas

Rice, Heather - NSCI
Regulation of the proteolytic processing and function of Amyloid Precursor Protein by candidate ligands
Advisor: Dennis Selkoe

Rosen, Jonathan - BBS
The function of the Heg-CCM pathway in zebrafish heart development
Advisor: John Mably

Ross, Leila - BBS
HARNESSING EVOLUTIONARY FITNESS IN PLASMODIUM FALCIPARUM FOR DRUG DISCOVERY AND SUPPRESSING RESISTANCE
Advisor: Dyann Wirth

Roy, Matthew - IMM
Development and application of a high-throughput RNAi screen to reveal novel components of the DNA sensing pathway
Advisor: Nir Hacohen

Sadegh, Cameron - NSCI
Directed differentiation of mouse embryonic stem cells into neocortical output neurons
Advisor: Jeffrey Macklis

Sage, Peter - IMM
Mechanisms of CD4 T cell antigen recognition and effector cell differentiation and function
Advisor: Arlene Sharpe

Salogiannis, John - NSCI
Regulation of excitatory synapse development by the RhoGEF Ephexin5
Advisor: Michael Greenberg

Sarraf, Shireen - BBS
Defining the landscape of the PARKIN- and PINK1-dependent ubiquitin-modified proteome in response to mitochondrial dysfunction
Advisor: J.Wade Harper

Shao, Diane - BBS
Functional Genomics Approaches to Identify and Characterize Oncogenic Signaling
Advisor: William Hahn

Shyer, Amy - BBS
The Role of Mechanical Forces in Patterning and Morphogenesis of the Vertebrate Gut
Advisor: Clifford Tabin

Tan, Meng Kwang Marcus - VIR
Deciphering the biological functions of F-box proteins through the use of Parallel Adaptor Capture (PAC) proteomics.
Advisor: J.Wade Harper

Tan, Min Jie Alvin - VIR
Identification of the Cellular Proteins and Pathways Engaged by the Bovine Papillomavirus Type 1 E6 and E7 Proteins
Advisor: Peter Howley

Terrell, Shariya - BBS
Importance of the Pre-NH2-Terminal Domain of HSV-1 DNA Polymerase for Viral Replication
Advisor: Don Coen

Thompson, Morgan - BBS
Evolutionarily Conserved Function of Huntingtin in Cellular Dynamics Related to Cell Adhesion and the Cytoskeleton
Advisor: Marcy MacDonald

Tukachinsky, Hanna - BBS
Mechanistic Studies of Vertebrate Hedgehog Signaling
Advisor: Adrian Salic

Van't Veer, Ashlee - NSCI
Role of Kappa-Opioid Receptors in Stress-Induced Behaviors
Advisor: William Carlezon

Vo, Annie - BBS
Glucose Metabolism in Cancer-Associated Fibroblasts
Advisor: Raghu Kalluri

Woodworth, Mollie - BBS
Transcriptional controls over neocortical projection neuron identity and connectivity
Advisor: Jeffrey Macklis

Wu, Melissa - BBS
Enhancing Myoblast Fusion for Therapy of Muscular Dystrophies
Advisor: Emanuela Gussoni

Wu, Zheng - NSCI
Molecular Dissection of Neural Circuits Underlying Parental Behavior in Mice
Advisor: Catherine Dulac

Xiang, Michael - BBS
Physiological and Pharmacological Regulation of the STAT3 Pathway in Cancer
Advisor: David Frank

Yang, Luhan - BBS
Development of Human Genome Editing Tools for the Study of Genetic Variations and Gene Therapies
Advisor: George Church

Yang, Yawei - BBS
ZNF335: A Novel Regulator of Stem Cell Proliferation and Cell Fate in the Cerebral Cortex
Advisor: Christopher Walsh

Yen, Po-Jen - VIR
SIV envelope glycoprotein determinants of macrophage tropism and their relationship to neutralization sensitivity and CD4-independent cell-to-cell transmission
Advisor: Dana Gabuzda

Yoo, Ronnie - BBS
Mechanisms of Stem Cell Regulation in Medulloblastoma
Advisor: Laurie Jackson-Grusby

Yu, Yueyang - BBS
Induction of Mitotic Alterations by the Human Papillomavirus Type 16 E7 Oncoprotein: Mechanistic Studies
Advisor: Karl Münger

2012

Albacker, Colleen - BBS
Chromatin-modifying factors in zebrafish models of rhabdomyosarcoma and hematopoiesis
Advisor: Leonard Zon

Alpert, Michael - VIR
Antibodies in Vaccine Protection against SIV and HIV-1 Infection
Advisor: David Evans

Alston, Jessica - BBS
Genetic and Functional Studies of Non-coding Variants in Human Disease
Advisor: David Altshuler

Beier, Kevin - BBS
Viral Tracing of Neuronal Circuitry
Advisor: Constance Cepko

Boyle, Patrick - BBS
Network-scale engineering: systems approaches to synthetic biology
Advisor: Pamela Silver

Brady, Daniel - NSCI
Mechanisms of Cross-Modal Refinement by Visual Experience
Advisor: Takao Hensch

Bruchez, Anna - VIR
Niemann-Pick C1 is essential for Ebola virus infection and a target of small molecule inhibitors
Advisor: Jim Cunningham

Burrows-Mazzucco, Anna - BBS
Genome-Wide Loss-of-Function Genetic Screens Identify Novel Senescence Genes and Putative Tumor Suppressors
Advisor: Stephen Elledge

Cenik, Can - BBS
Studies on the Evolution and Function of Introns in 5’Untranslated Regions
Advisor: Frederick Roth

Chevrier, Nicolas - IMM
Systems-Level Analysis of the Toll-like Receptor Network of Dendritic Cells
Advisor: Nir Hacohen

Cohen, Nicole - BBS
Selective Small Molecule Targeting of Anti-Apoptotic MCL-1
Advisor: Loren Walensky

De la Huerta, Irina - NSCI
Expression and Role of Cadherins in the Mammalian Visual System
Advisor: Joshua Sanes

DeGrace, Marciela - VIR
RNAi screens in primary human lung cells reveal Hermansky-Pudlak Syndrome proteins as influenza suppressors
Advisor: Nir Hacohen

Dempsey, Jamie - BBS
SRPK2 phosphorylation by the AGC kinases, and mTORC1 regulation of alternative splicing
Advisor: John Blenis

Draganov, Dobrin - IMM
MFG-E8 Blockade Enhances Tumor Immunity in a Murine Breast Cancer Model
Advisor: Glenn Dranoff

DuBoff, Brian - BBS
Disruption of mitochondrial dynamics in tauopathy
Advisor: Mel Feany

Eggert, Stacey - BBS
Identification and Characterization of Genetic Variants Conveying Risk to Develop Uterine Leiomyomata
Advisor: Cynthia Morton

Finley, Lydia - BBS
Regulation of metabolic reprogramming by sirtuins and calorie restriction
Advisor: Marcia Haigis

Follmer, Nicole - BBS
Investigation of the inheritance of Polycomb Group-dependent repression through mitosis
Advisor: Nicole Francis

Ganesh, Vijay - NSCI
Identification and Characterization of Genes Essential for Human Brain Development
Advisor: Christopher Walsh

Gelfand, Maria - NSCI
Characterization of the in vivo function of Neuropilin1 during development
Advisor: Chenghua Gu

Grau, Daniel - BBS
Mechanistic studies of Polycomb group proteins
Advisor: Robert Kingston

Han, Juliette - NSCI
The Role of TSC in Oligodendrocyte Differentiation and Myelination
Advisor: Mustafa Sahin

Hebert, Alan - BBS
Functional Relationship Between Merlin and the ERM Proteins
Advisor: Andrea McClatchey

Hong, Soyon - NSCI
Probing the in vivo economy of amyloid beta-protein during the development of Alzheimer’s disease-type pathology
Advisor: Dennis Selkoe

Hu, Jimmy - BBS
Diverse Roles of Cell Signaling during Early and Late phases of Limb Development
Advisor: Clifford Tabin

Huang, Hsuan-Ting - BBS
Epigenetic Regulation of Hematopoiesis in Zebrafish
Advisor: Leonard Zon

Huang, Kuo-Hua - NSCI
Control of Turning Behaviors by Spinal Projection Neurons in the Larval Zebrafish
Advisor: Florian Engert

Hung, Yin - BBS
Single Cell Imaging of Metabolism with Fluorescent Biosensors
Advisor: Gary Yellen

Janas, Maja - BBS
Novel regulation of microRNA biogenesis and function
Advisor: Carl Novina

Kaanta, Alice - BBS
Evidence for a novel multipotent mammary progenitor with pregnancy-specific activity
Advisor: Joan Brugge

Kane, Elizabeth - BBS
The sensory and behavioral basis of Drosophila larval phototaxis
Advisor: Aravinthan Samuel

Kawasaki, Jun - BBS
RASA1 Function in Vascular Development and Disease
Advisor: Joanne Chan

Kiely, Christine - BBS
Spt6 regulates transcription and chromatin structure in the fission yeast, Schizosaccharomyces pombe
Advisor: Fred Winston

Kim, Irene - VIR
Mechanisms of membrane disruption by viral entry proteins
Advisor: Stephen Harrison

Kim, Minsu - BBS
Regulatory Interaction of the Class III PI3 Kinase Complex and p53
Advisor: Junying Yuan

Kranzusch, Philip - VIR
Architecture and regulation of the arenavirus polymerase complex
Advisor: Sean Whelan

Kwiatkowski, Nicholas - BBS
Development of Mps1, Aurora and Cdk7 inhibitors and their application to the analysis of the cell cycle
Advisor: Nathanael Gray

Lapan, Ariya - BBS
Melanoma Cell Adhesion Molecule is Associated with Myogenicity in Multiple Progenitor Populations within Human Fetal Skeletal Muscle
Advisor: Emanuela Gussoni

Lee, Amy - VIR
Ribosome-mediated specificity in vesicular stomatitis virus mRNA translation defines a new role for rpL40 during initiation
Advisor: Sean Whelan

Lehnert, Brendan - NSCI
The role of TRP channels in auditory transduction and amplification in Drosophila
Advisor: Rachel Wilson

Li, Victor - BBS
The cell cycle and differentiation in stem cells
Advisor: Marc Kirschner

Lin, Chieyu - BBS
Developmental Origins of Aggressive Medulloblastoma
Advisor: Laurie Jackson-Grusby

Liu, Jianing - BBS
Molecular Modulators of Hematopoiesis and Leukemogenesis
Advisor: Amy Wagers

Markovski, Monica - BBS
Bacterial cell wall synthases require outer membrane lipoprotein cofactors
Advisor: Thomas Bernhardt

Mefford, Megan - VIR
MOLECULAR AND BIOINFORMATIC ANALYSIS OF NEUROTROPIC HIV ENVELOPE GLYCOPROTEINS
Advisor: Dana Gabuzda

Min, Lia - NSCI
Experience-Dependent Loss of Cross-Modal Plasticity in Mouse Visual Cortex
Advisor: Michela Fagiolini

Mitra, Devarati - BBS
THE ROLE OF PIGMENTATION AND ONCOGENIC BRAF IN MELANOMA
Advisor: David Fisher

Mizeracka, Karolina - BBS
Functional analysis of Notch signaling during vertebrate retinal development
Advisor: Constance Cepko

Moffett, Howell - IMM
MicroRNAs in normal and malignant lymphocytes
Advisor: Kai Wucherpfennig

Mooster, Jana - IMM
Mechanisms of immunodeficiency due to NFkappaB signaling defects
Advisor: Raif Geha

Morris-Singer, Corey - BBS
A Role for Nucleoporin Nup211 in Centromere Structure and Function in Schizosaccharomyces pombe
Advisor: Danesh Moazed

Mukerji, Joya - VIR
A NOVEL EXOCYST-BASED MECHANISM FOR HIV NEF-MEDIATED ENHANCEMENT OF INTERCELLULAR NANOTUBE FORMATION
Advisor: Dana Gabuzda

Ng, Mei - BBS
Mechanical Regulation of Epithelial Cell Collective Migration
Advisor: Joan Brugge

Ni, Amy - NSCI
Visual Attention and the Role of Normalization
Advisor: John Maunsell

O'Connell, Daniel - BBS
An Epithelial-Mesenchymal Gene Regulatory Network that Controls Tooth Organogenesis
Advisor: Richard Maas

Osuna-Gutierrez, Christa - IMM
Characterization of the Mamu-A*01-restricted CD8-positive T lymphocyte immunodominance hierarchy in simian immunodeficiency virus-infected rhesus monkeys
Advisor: Norman Letvin

Paik, Elizabeth - BBS
Caudal transcription factors in hematopoietic development
Advisor: Leonard Zon

Park, Eunyong - BBS
Mechanistic studies of SecY-mediated protein translocation in intact Escherichia coli cells
Advisor: Tom Rapoport

Price, Nathan - BBS
The role of SIRT1 in preventing mitochondrial dysfunction with obesity and aging
Advisor: David Sinclair

Rahman, Shaila - VIR
Molecular insight into function of the evolutionarily conserved Brd4 extraterminal domain (ET) and mechanism of Brd4 functions in human diseases
Advisor: Peter Howley

Ramirez, Cherie - BBS
Improving Zinc Finger Nucleases –Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects
Advisor: Jae Joung

Ramos, Alexis - BBS
Cancer Genome Characterization with SNP Array and Whole-Exome Sequencing Analysis
Advisor: Matthew Meyerson

Ramsdell, Talia - BBS
Molecular Motors of ESX-type Secretion Systems
Advisor: Sarah Fortune

Rossin, Elizabeth - BBS
The proteomic landscape of human disease: construction and evaluation of networks associated to complex traits
Advisor: Mark Daly

Ruff, Douglas - NSCI
Neuronal Tuning and its Role in Attention
Advisor: Richard Born

Schrock, Alexa - BBS
Signaling and Feedback Networks Underlying Sensitivity and Resistance to Kinase Inhibitors in Oncogene Addicted Cancers
Advisor: Jeffrey Engelman

Shore, David - BBS
Cytoprotective Pathways that Contribute to Lifespan Extension in C. elegans
Advisor: Gary Ruvkun

Sircar, Piya - IMM
Clonal analysis of mucosal SIV-specific CD8+ T cell responses
Advisor: Norman Letvin

Smolyanskaya, Alexandra - NSCI
Dynamics of cortical decision circuits during changes in the fidelity of sensory representations
Advisor: Richard Born

Soskis, Michael - NSCI
A chemical-genetic study of EphB receptor tyrosine kinase signaling in the developing nervous system
Advisor: Michael Greenberg

Spangle, Jennifer - VIR
Regulation of Growth Factor and Nutrient Sensing Pathways by Human Papillomavirus E6 Proteins
Advisor: Karl Münger

Su, Xiaolei - BBS
Regulation of Microtubule Dynamics by Molecular Motors
Advisor: David Pellman

Tajonar, Adriana - BBS
Genetic Approaches to Study Human Embryonic Stem Cell Self-Renewal and Survival
Advisor: Douglas Melton

Taylor, Alison - BBS
Ribosomal Protein Mutations in Hematopoiesis and Zebrafish Development
Advisor: Leonard Zon

Thompson-Peer, Katherine - BBS
Transcriptional Regulation of Synapse Remodeling in C. elegans
Advisor: Joshua Kaplan

Turner, Keith - BBS
Bistability in Pseudomonas aeruginosa
Advisor: Simon Dove

Vo, Thanh-Trang - BBS
Mitochondrial Priming Determines Chemotherapeutic Response in Acute Myeloid Leukemia
Advisor: Anthony Letai

Wang, Alice - NSCI
Neural substrates of choosing actions and motivational drive, a role for the striatum
Advisor: Naoshige Uchida

Wang, Charlotte - BBS
A ChIP-mass spectrometry approach to analysis of dosage compensation in Drosophila
Advisor: Mitzi Kuroda

Wang, Oulu - NSCI
Glucocorticoids regulate kisspeptin neurons during stress and contribute to infertility and obesity in leptin-deficient mice
Advisor: Joseph Majzoub

Wang, Xun - BBS
IRF3 is a Critical Regulator of Adipose Glucose and Energy Homeostasis
Advisor: Evan Rosen

Wheeler, Lee - IMM
CD4 aptamer-siRNA chimeras (CD4-AsiCs) knockdown gene expression in CD4+ cells and inhibit HIV transmission
Advisor: Judy Lieberman

Wivagg, Carl - BBS
Molecular Genetics of Beta-Lactam Sensitivity and Resistance in Mycobacterium tuberculosis
Advisor: Deborah Hung

Xu, Cong - BBS
Early Cell Fate Determination in Zebrafish
Advisor: Leonard Zon

Yang, Desiree - BBS
The ABC’s of Cell Division: Regulation of Peptidoglycan Amidase Activity During Cytokinesis in Escherichia coli
Advisor: Thomas Bernhardt

Yang, Kailin - BBS
Regulation of the Fanconi Anemia Pathway by Deubiquitination
Advisor: Alan D'Andrea

Zhang, Tingting - IMM
Elucidating Mechanisms of IgH Class Switch Recombination Involving Switch Regions and Double Strand Break Joining
Advisor: Frederick Alt

Zhou, Alicia - BBS
Elucidating the regulation and effectors of the breast cancer oncogene, IKKepsilon
Advisor: William Hahn

Zhou, Vicky - BBS
Methods for Global Characterization of Chromatin Regulators in Human Cells
Advisor: Bradley Bernstein

Zhou, Yi - NSCI
Olfactory Transduction and Taste Processing in Drosophila
Advisor: Rachel Wilson

Zwemer, Lillian - BBS
Allele-specific gene expression in the laboratory mouse
Advisor: Andrew Chess

2011

Agapakis, Christina - BBS
Biological design principles for synthetic biology
Advisor: Pamela Silver

Agyemang, Amma - IMM
Regulation of Self-Reactive B cells: Implications for Complement and Toll-like Receptors
Advisor: Michael Carroll

Albacker, Lee - IMM
The Phosphatidylserine Receptor TIM-4 Tunes the Adaptive Immune Response
Advisor: Dale Umetsu

Baughman, Joshua - BBS
Computational and Genetic Screens for Regulators of Oxidative Phosphorylation
Advisor: Vamsi Mootha

Billings, Nathan - BBS
Thyroid Hormone Signaling during Chick Retinal Development
Advisor: Constance Cepko

Boboila, Cristian - IMM
DNA Repair Pathways Involved in B Cell Class Switch Recombination and Chromosomal Translocations
Advisor: Frederick Alt

Bock, Dravida - NSCI
Network anatomy and in vivo physiology from a group of visual cortical neurons
Advisor: R. Clay Reid

Cale, Evan - IMM
Mechanisms used by simian immunodeficiency viruses to evade virus-specific CD8-positive T lymphocyte responses
Advisor: Norman Letvin

Carter, Brett - NSCI
Sodium Current during and between Action Potentials of GABAergic and Glutamatergic Neurons
Advisor: Bruce Bean

Cedeno Laurent, Filiberto - IMM
Galectin-1 – Galectin-1 Ligand Axis and Its Significance in Immunity
Advisor: Charles Dimitroff

Chao, Michael - BBS
Post-transcriptional control of the essential autolysin RipA in Mycobacterium tuberculosis
Advisor: Eric Rubin

Chen, An-Jou - BBS
Identification and Characterization of Genetic Targets in Gliomagenesis
Advisor: Ronald DePinho

Chiang, Charleston - BBS
Considerations of evolutionary conservation and genetic ancestry in human genetic association studies
Advisor: Joel Hirschhorn

Chou, Danny - BBS
The DNA Damage Response in Mammalian Cells
Advisor: Stephen Elledge

Christofferson, Dana - BBS
A study of necroptosis and its control by RIP1 kinase
Advisor: Junying Yuan

Chung, Hachung - BBS
Gut Immune Maturation Depends Upon Colonization with Host-Specific Microbiota
Advisor: Dennis Kasper

Clower- Purington, Cynthia - BBS
hnRNPs A1 and A2 Control Alternative Splicing of PK-M and Mediate Metabolic Programming of Cancer Cell Metabolism
Advisor: Lewis Cantley

Cohen, Nadia - IMM
Invariant Natural Killer T cell activation by fungi
Advisor: Michael Brenner

Cohen, Sonia - BBS
Activity-Dependent Phosphorylation of MeCP2 in Neural Development and Rett Syndrome
Advisor: Michael Greenberg

Cohick, Claudine - BBS
Protein Kinase D Signaling Through Substrate Phosphorylation in Endocytic Trafficking
Advisor: Alex Toker

Curtis, Stephen - BBS
Lung tumor-propagating cells: importance of genotype and a role in metastasis
Advisor: Carla Kim

Cury, Kevin - NSCI
The Role of Spike Timing in Odor Coding During Sniffing
Advisor: Naoshige Uchida

Dakin, Kelly - NSCI
Novel Biological Functions of Hemoglobin in the Brain
Advisor: Bruce Yankner

De Leon-Vazquez, Erika - VIR
Investigation of the Roles of the KSHV Latency Associated Nuclear Antigen Internal Regions in Episome Persistence.
Advisor: Ken Kaye

Feeney, Morgan - BBS
Rewiring thiol-redox pathways of electron transfer in Escherichia coli
Advisor: Jonathan Beckwith

Fitzgerald, Jamie - NSCI
Generalized associative representations in parietal cortex
Advisor: John Assad

Flusberg, Deborah - BBS
Life-Death Signaling and Sensitivity to Death Ligands in Subpopulations of Cells
Advisor: Peter Sorger

Ford, Knatokie - BBS
Role of VEGF in the Adult: A Tale of Two Epithelia
Advisor: Patricia D'Amore

Gerace, Erica - BBS
Regulation of RNA-mediated Heterochromatin Assembly in S. pombe
Advisor: Danesh Moazed

Giusti-Rodriguez, Paola - BBS
Assessing the roles of Cdk5/p25 in synaptic plasticity and neurodegeneration
Advisor: Li-Huei Tsai

Grassian, Alexandra - BBS
Extracellular Matrix and Oncogene Regulation of Growth Factor Signaling and Cellular Metabolism
Advisor: Joan Brugge

Herman, Daniel - BBS
Massively parallel, targeted DNA resequencing and cardiovascular disease
Advisor: Jonathan Seidman

Hite, Richard - BBS
Lipid-Protein Interactions in Two-Dimensional Crystals of Aquaporin-0
Advisor: Thomas Walz

Ho, Dennis - BBS
Discovery and Validation of Prognosis Determinants in Cancer Progression
Advisor: Ronald DePinho

Hom, Sabrina - BBS
Trans-Synaptic Signaling at C. elegans Neuromuscular Junctions
Advisor: Joshua Kaplan

Houser, Brandy - IMM
Macrophage populations at the human maternal-fetal interface
Advisor: Jack Strominger

Hu, Chi-Kuo - BBS
Spatiotemporal Regulation of Microtubules during Cytokinesis
Advisor: Timothy Mitchison

Hubbard, Basil - BBS
Mechanisms of Mammalian Sirtuin Regulation in Health and Disease
Advisor: David Sinclair

Ilic, Nina - BBS
The PI3K - pathway in tumorigenesis and cancer drug resistance
Advisor: Thomas Roberts

Jehl, Stephanie - BBS
The role of innate and adaptive immune mediators in the intracellular recognition of Shigella flexneri
Advisor: Michael Starnbach

Jun, Lucy - BBS
Mechanisms of obesity-induced insulin resistance: A possible role for Lipocalin 2
Advisor: Evan Rosen

Kaczmarek, Jan - NSCI
Novel activation mechanisms of TRPC5 reveal its participation in neuronal growth cone collapse
Advisor: David Clapham

Kerlin, Aaron - NSCI
Response properties of inhibitory neuron subtypes in mouse visual cortex
Advisor: R. Clay Reid

Kloimwieder, Anne - BBS
An investigation of sporulation and germination in Saccharomyces cerevisiae
Advisor: Fred Winston

Leon, Luis - IMM
Saposin B and C facilitate CD1 lipid loading by different mechanisms
Advisor: Michael Brenner

Litterman, Nadia - NSCI
A Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning
Advisor: Azad Bonni

Loya, Carlos - BBS
MicroRNA Control of Synapse Development
Advisor: David Van Vactor

Lukens, Amanda - BBS
The identification of novel variant surface antigens of Plasmodium falciparum
Advisor: Dyann Wirth

Madigan, Cressida - BBS
Lipidomic and genetic dissection of the M. tuberculosis iron scavenging response
Advisor: D. Branch Moody

Mahoney, Sarah - BBS
AGC kinases: new targets and crosstalk nodes
Advisor: John Blenis

McKenna, Elizabeth - BBS
Epigenetically driven tumor suppression by SNF5
Advisor: Charles Roberts

McLoon, Anna - BBS
Genetic studies on the regulation of biofilm formation and the domestication of the bacterium Bacillus subtilis
Advisor: Richard Losick

McManus, Heather - BBS
Genome-wide location analysis of H-NS family members and studies of the control of cupA gene expression in P. aeruginosa
Advisor: Simon Dove

Miller, Peter - IMM
Targeting Leukemia Stem Cells in the Hematopoietic Niche
Advisor: Benjamin Ebert

Mora-Blanco, Eva - BBS
Regulation of the Wnt and Hedgehog Signaling Pathways by the Swi/Snf Complex
Advisor: Charles Roberts

Morelli, Marco - VIR
The Role of HIV-1 Membrane in Neutralization by gp41 MPER-directed Broadly Neutralizing Antibodies
Advisor: Stephen Harrison

Moseman, Elliott - IMM
Antiviral functions of lymph node subcapsular sinus macrophages
Advisor: Ulrich von Andrian

Myoga, Michael - NSCI
Calcium-Dependent Synaptic Plasticity in the Cerebellum
Advisor: Wade Regehr

Nottke, Amanda - BBS
Investigations into the roles of a histone demethylase during meiosis
Advisor: Yang Shi

Olsen, Rachelle - BBS
Analysis of Antizyme Inhibitor Function in Prostate Tumor Growth and Centrosome Amplification
Advisor: Bruce Zetter

Panas, Michael - IMM
The identification and elimination of immunosuppressive Mycobacterium bovis BCG genes to create novel rBCG vectors that generate increased CD8+ T cell responses
Advisor: Norman Letvin

Pastor, William - BBS
Studies of 5.8S ribosomal RNA biogenesis and 5-hydroxymethylcytosine mapping
Advisor: Anjana Rao

Pielak, Rafal - BBS
The influenza M2 proton channel: mechanism of proton conductance, inhibition and resistance
Advisor: James Chou

Piskounova, Elena - BBS
Post-transcriptional regulation of let-7 microRNA expression in embryonic stem cells and cancer
Advisor: Richard Gregory

Plant, Joshua - BBS
ESCRT-II links RNA localization to endosomal trafficking
Advisor: Michael Blower

Puram, Sidharth - BBS
Calcium-Regulated Ubiquitin Signaling at the Centrosome Drives Dendrite Patterning in the Mammalian Brain
Advisor: Azad Bonni

Reynoso, Erika - IMM
Insights into the maintenance and regulation of CD8+ T cell tolerance to the small intestine
Advisor: Shannon Turley

Roush- Brown, Rebecca - BBS
Biosynthesis of N-P Bond Containing Peptide Natural Products
Advisor: Christopher T Walsh

Russel, Sascha - BBS
Genetic and functional genomic analysis of C. elegans molting
Advisor: Gary Ruvkun

Schmidt, Aaron - VIR
Inhibition by Small Molecules and Peptides of Dengue-virus Fusion and Entry
Advisor: Stephen Harrison

Schneiderman, Jonathan - BBS
‘Don’t worry, I’ve got it covered!’ – Replication-independent nucleosome assembly and the maintenance of chromatin
Advisor: Kami Ahmad

Senapedis, William - BBS
Forkhead at the Crossroads of Cancer and Healthy Lifespan
Advisor: Pamela Silver

Shrestha, Yashaswi - BBS
Deciphering Mechanisms of Cell Transformation through Functional Genomics
Advisor: William Hahn

Sikorski, Timothy - BBS
Identification of Promoter Associated Factors with Quantitative Proteomics
Advisor: Stephen Buratowski

Smurnyy, Yegor - BBS
Studying cytokinesis using small molecule tools
Advisor: Ulrike Eggert

Stewart, Michelle - BBS
Targeting the Anti-Apoptotic Protein MCL-1 in Human Cancer
Advisor: Loren Walensky

Storer, Narie - BBS
Characterization of the myogenic program in zebrafish rhabdomyosarcoma
Advisor: Leonard Zon

Sung, Jung Hwan - BBS
Chemokine Guidance of Anti-Viral Memory T Cell Responses in the Lymph Node
Advisor: Ulrich von Andrian

Terzi, Nihal - BBS
A Functional Connection between Noncoding RNA Polymerase II Transcription and Chromatin
Advisor: Stephen Buratowski

Trevino, Simon - BBS
Mosaic nucleic acids that bind purine nucleotides
Advisor: Jack Szostak

Tse, Joyce - BBS
Functional Heterogeneity of Fibroblasts in Cancer Progression and Metastasis
Advisor: Raghu Kalluri

Tubo, Noah - BBS
Molecular Requirements for the Tissue Specific Trafficking of T Cells
Advisor: James Campbell

Vong, Sylvia - BBS
The Functional Contribution of Alpha Smooth Muscle Actin-Positive Myofibroblasts in the Initiation of Lung Cancer
Advisor: Raghu Kalluri

Wilbuer, Anne-Kathrin - IMM
The mechanism of human leukocyte antigen DM action
Advisor: Kai Wucherpfennig

Woo, Janghee - BBS
Mesenchyme-epithelial interactions in gastrointestinal development and tumorigenesis
Advisor: Ramesh Shivdasani

Yan, Han - BBS
NETWORK PERSPECTIVES OF BIOLOGICAL SYSTEMS
Advisor: Marc Vidal

Zeng, Xing - BBS
Mechanism of Small Molecule Inhibitors of the Anaphase-Promoting Complex/Cyclosome
Advisor: Randall King

2010

Abdel-Azim, Eiman - NSCI
Molecular Controls over Neocortical Neuronal Diversity and Oligodendrocyte Development
Advisor: Jeffrey Macklis

Ahn, Sejin - BBS
Regulation of the inv1+ gene in Schizosaccharomyces pombe
Advisor: Fred Winston

Aoki, Scott - VIR
The Role of Outer Capsid Glycoprotein VP7 in Assembly, Neutralization, and Maturation of the Rotavirus Triple Layered Particle
Advisor: Stephen Harrison

Appler, Jessica - NSCI
The Molecular and Morphological Development of Spiral Ganglion Neurons
Advisor: Lisa Goodrich

Armour, Sean - BBS
Characterization of mammalian sirtuin regulators, targets, and complexes
Advisor: David Sinclair

Baca, Quentin - BBS
Adaptor proteins regulate cellular functions in the context of a dynamic membrane interface
Advisor: David Golan

Baltz- Adamo, Jennifer - BBS
Structural, Biochemical, and Biophysical Characterization of the KSHV DNA Polymerase Accessory Subunit, PF-8
Advisor: James Hogle

Bilimoria, Parizad - NSCI
Signaling Mechanisms Regulating Neuronal Morphogenesis in the Cerebellar Cortex
Advisor: Azad Bonni

Bolcome, Robert - BBS
Consequences of Anthrax Lethal Toxin Action on the Vasculature
Advisor: Joanne Chan

Bortnick, Rachel - NSCI
Genetic Dissection of the Dscam Pathway
Advisor: Dietmar Schmucker

Boyden, Steven - BBS
Genetics of Exceptional Human Longevity, Interstitial Cystitis, and Hereditary Myopathies
Advisor: Louis Kunkel

Bracha, Abigail - BBS
Metabolism-mediated Control of Cellular Differentiation
Advisor: Donald Ingber

Brown, Keturah - IMM
Characterizing the roles of the PD-1 ligands, PD-L1 and PD-L2, in regulating the T cell response to Influenza virus
Advisor: Arlene Sharpe

Bruckner, Raphael - BBS
Material properties of protocellular and biological membranes
Advisor: Jack Szostak

Buchman, Joshua - NSCI
Roles of centrosome proteins associated with primary microcephaly in mammalian corticogenesis
Advisor: Li-Huei Tsai

Carmona, Juan - BBS
Sirtuin-mediated mechanisms of homeostasis and aging in metazoans
Advisor: David Sinclair

Charity, James - BBS
Transcription regulation of virulence gene expression in Francisella tularensis
Advisor: Simon Dove

Courchesne-Schlink, Stephanie - NSCI
Spatial Aspects of Neuronal Survival Signaling in Sensory Neurons
Advisor: Rosalind Segal

de la Torre Ubieta, Luis - NSCI
Transcriptional Regulation of Neuronal Polarity
Advisor: Azad Bonni

Dufu, Kobina - BBS
Role of the human TREX complex in mRNA Export
Advisor: Robin Reed

Dutton, Rachel - BBS
Vitamin K epoxide reductase homologues provide an alternative pathway for bacterial disulfide bond formation
Advisor: Jonathan Beckwith

Elenko, Mark - BBS
Single-Molecule Studies of RNA Aptamer Binding
Advisor: Jack Szostak

Erwin, Jennifer - BBS
Regulation of Imprinted X-Chromosome Inactivation in Stem Cells and the Early Embryo
Advisor: Jeannie Lee

Fell, Gillian - BBS
The role of the endogenous opioid beta-endorphin in systemic and behavioral responses to radiation exposure
Advisor: David Fisher

Floyd, Daniel - BBS
Single particle studies of influenza viral membrane fusion
Advisor: Antoine van Oijen

Fry, Jessica - BBS
ADAM9 Metalloproteases and Breast Cancer Cell Migration
Advisor: Alex Toker

Garg, Salil - IMM
Arl8b directs lysosomal trafficking in antigen presentation and microbial defense
Advisor: Michael Brenner

Garrity, Sean - BBS
A bacteria-based experimental system for the study of prion proteins
Advisor: Ann Hochschild

Giessel, Andrew - NSCI
Local, Non-linear Regulation of Synaptic Signals at Dendritic Spines of CA1 Pyramidal Cells
Advisor: Bernardo Sabatini

Goldman, Joseph - BBS
Roles for histone H2A variants in gene regulation
Advisor: Robert Kingston

Gray, Andrew - BBS
Characterization of the role of YidC in Escherichia coli membrane protein biogenesis
Advisor: Marcia Goldberg

Greenblatt, Matthew - IMM
TAK1 in Skeletal Homeostasis
Advisor: Laurie Glimcher

Hartlerode, Andrea - BBS
Studies on Sister Chromatid Recombination in Mammalian Cells
Advisor: Ralph Scully

Heindl, Jason - BBS
Host Complicity in Intercellular Spread of Shigella flexneri
Advisor: Marcia Goldberg

Hong, Youn-Young - NSCI
Structure and Development of Retinal Ganglion Cells
Advisor: Joshua Sanes

Huynh, Mai Anh - BBS
Role of the Cdh1-APC/SnoN Pathway in Neuronal Morphogenesis
Advisor: Azad Bonni

Jang, Il Ho - BBS
The role of Notch signaling in hemogenic endothelial cell development
Advisor: George Daley

Jensen- Rajani, Danielle - BBS
Degradation of multiple hnRNPs during apoptosis
Advisor: Judy Lieberman

Kamei, Caramai - BBS
Patterning the Vertebrate Mesoderm: Functional Analysis of Bone Morphogenetic Protein-responsive Genes in Vasculogenesis and Kidney Development
Advisor: Clifford Tabin

Kamp, Heather - BBS
Regulatory mechanisms controlling temperature-dependent transcription of flagellar motility genes in Listeria monocytogenes
Advisor: Darren Higgins

Knoll, Allison - NSCI
Role of Kappa Opioid Receptors in Fear and Anxiety-like Behaviors in Rats
Advisor: William Carlezon

Knowlton, Melodie - BBS
Analysis of CSF-1R and SRC-induced tyrosine phosphorylation in breast epithelial cells
Advisor: Joan Brugge

Koh, Andrew - IMM
Aire’s histone-binding module in mediating immunological tolerance
Advisor: Diane Mathis

Kolokotrones, Thomas - BBS
Curvature in Metabolic Scaling
Advisor: Walter Fontana

Kurshan, Peri - NSCI
The Role of Alpha2delta-3 in Calcium-Channel Localization, Synaptic Function and Bouton Formation
Advisor: Thomas Schwarz

Le, Xiuning - BBS
RAS related cancer modeling and chemical genetics in the zebrafish
Advisor: Leonard Zon

Li, Geng - BBS
The Mechanism of Sir3-Nucleosome Interaction and its Implications in Silent Chromatin Assembly in Saccharomyces cerevisiae
Advisor: Danesh Moazed

Li, Linyu - BBS
TRPML3, an endosomal cation channel, regulates polarized membrane trafficking in epithelial cells
Advisor: David Clapham

Lucas, Carrie - BBS
Mechanisms of Deletional Tolerance of Peripheral CD8+ T Cells Induced by Anti-CD40L and Allogeneic Bone Marrow Transplantation
Advisor: Megan Sykes

Ma, Amy - BBS
Characterization of type VI secretion in Vibrio cholerae
Advisor: John Mekalanos

Magnotti, Laura - NSCI
Gap Junctions Between Astrocytes and Oligodendrocytes are Critical for Normal Glial Function
Advisor: David Paul

Mammarella, Nicole - BBS
The role of apoplastic peroxidases in the Arabidopsis thaliana defense response
Advisor: Frederick Ausubel

Marotta , Lauren - BBS
Investigations of intra-tumor heterogeneity in breast cancer
Advisor: Kornelia Polyak

McDonald, Rebecca - IMM
RNAi screening in dendritic cells identifies Fbxw11 as a regulator of interleukin-12/23
Advisor: Nir Hacohen

Mermel, Craig - BBS
The Analysis of Somatic Copy Number Alteration in Human Cancers
Advisor: Matthew Meyerson

Moore, Michael - BBS
Alternative Splicing Networks in Cell Differentiation and Programmed Cell Death
Advisor: Pamela Silver

Neal, Jason - NSCI
Insights into the role of Filamin A and ARFGEF2 genes in periventricular heterotopia formation
Advisor: Christopher Walsh

Nielsen, Corinne - BBS
Epithelial-vascular co-development in the hindbrain choroid plexus
Advisor: Susan Dymecki

Nowakowski, Dan - BBS
Novel Activities of Adenomatous Polyposis Coli (APC) Protein and Type III Neuregulin1 in the Developing Nervous System
Advisor: John Flanagan

Powell, Maria - BBS
A proteomic and functional analysis of the human papillomavirus E8^E2C protein
Advisor: Peter Howley

Rodgers, Mary - BBS
Hepatitis B and C viruses alter cholesterol metabolism by novel mechanisms
Advisor: Priscilla Yang

Rodriguez-Manzanet, Roselynn - IMM
The roles of TIM-4 in Innate and Adaptive Immunity
Advisor: Vijay Kuchroo

Rogers, Thomas - VIR
Intrinsic Immune Response to Viral Replication in Primates
Advisor: Norman Letvin

Rosenbaum, Abraham - BBS
Technologies for Sequencing and Interpreting Personal Genomes
Advisor: George Church

Sadacca, Leigh - NSCI
Circadian Clocks in Behavior and Physiology
Advisor: Charles Weitz

Schrum, Jason - BBS
Function and Properties of Phosphoramidate DNA as a Model Protocell Genome
Advisor: Jack Szostak

Schulman, Sol - BBS
Secretory Protein Biogenesis: From Membrane Translocation to Vitamin K-Dependent Disulfide Bridge Formation
Advisor: Tom Rapoport

Sheu, Shu-Hsien - BBS
Postnatal reorganization of axons that innervate a parasympathetic end-organ
Advisor: Jeff Lichtman

Shibata, Yoko - BBS
Mechanisms shaping the peripheral endoplasmic reticulum
Advisor: Tom Rapoport

Silva, Lindsey - BBS
Role for the nuclear lamina during early stages of herpes simplex virus 1 infection
Advisor: David Knipe

Spivey, Kristin - BBS
Analyses of collagen XXIII expression and function in non-small cell lung cancer
Advisor: Bruce Zetter

Sturgill, James - NSCI
Activity-dependent Regulation of Synapse Structure and Function: Roles of PSD-95 and the Metabolic Sensor, AMPK
Advisor: Bernardo Sabatini

Tanner, Nathan - BBS
Single-Molecule Studies of Escherichia coli DNA Replication
Advisor: Antoine van Oijen

Terashima, Alexandra - BBS
Negative feedback regulation of Nodal signaling in zebrafish mesendoderm patterning
Advisor: Iain Drummond

Tian, Meng - BBS
The molecular cloning and characterization of Fam46c RNA stability factor
Advisor: Mark Fleming

Umbarger, Mark - BBS
New Tools to Probe Bacterial Chromosome Folding
Advisor: George Church

Uzri, Dina - VIR
RIG-I-Dependent Innate Immune Signaling by Hepatitis C Virus RNAS
Advisor: Lee Gehrke

Vander Lugt, Bryan - IMM
Dendritic Cell Maturation and T Cell Immunosurveillance in Cutaneous Immunity
Advisor: James Campbell

Witt, Rochelle - NSCI
Of Structure and Function: The Nature of the Sonic Hedgehog-Heparan Sulfate Proteoglycan Interaction
Advisor: Rosalind Segal

Yang, Yue - NSCI
A Cdc20-APC Ubiquitin Signaling Pathway Regulates Presynaptic Differentiation
Advisor: Azad Bonni

Yuan, Tina - BBS
Contributions of Phosphoinositide-3-Kinase to Tumorigenesis both Inside and Outside the Tumor
Advisor: Lewis Cantley

2009

Abraira, Victoria - NSCI
Molecular Mechanisms of Inner Ear Morphogenesis
Advisor: Lisa Goodrich

Adamo, Luigi - BBS
Biomechanical Control of Hematopoiesis
Advisor: Guillermo Garcia-Cardeña

Ang Cambronne, Xiaolu - BBS
Substrates of the SCF-beta-TRCP E3 Ubiquitin Ligase Complex: Mechanisms of Recognition and Delivery to the Proteasome.
Advisor: J.Wade Harper

Arboleda-Velasquez, Joseph - BBS
NOTCH SIGNALING IN ISCHEMIC STROKE AND CADASIL
Advisor: Spyridon Artavanis-Tsakonas

Aw, Sherry - BBS
Potassium channel function as a regulator of developmental morphogenesis
Advisor: Michael Levin

Barker, Brianne - IMM
Critical Role for Interleukin-21 in Antiviral CD8-positive T Lymphocyte Responses
Advisor: Norman Letvin

Buker, Shane - BBS
Two Different Argonaute Complexes are Required for siRNA Generation and Heterochromatin Formation in Fission Yeast
Advisor: Danesh Moazed

Cameron, Douglas - BBS
An ordered mutant library and its use in defining flagellar biosynthesis and biofilm formation in Vibrio cholerae
Advisor: John Mekalanos

Chang, Jennifer - BBS
The histone regulatory proteins Spt10 and Spt21: roles in growth and silencing in Saccharomyces cerevisiae
Advisor: Fred Winston

Chen, Allen - BBS
Aph-1 functions as a substrate docking site within the Alzheimer’s disease relevant gamma-secretase complex
Advisor: Dennis Selkoe

Chen, Yao - BBS
Mechanism to Establish Graded Mapping Labels in the Embryonic Midbrain
Advisor: John Flanagan

Cherry, Timothy - BBS
An Analysis of Amacrine Cell Diversity and Development
Advisor: Constance Cepko

Chiu, Isaac - IMM
The Role of Innate and Adaptive Immunity in Amyotrophic Lateral Sclerosis
Advisor: Michael Carroll

Choo, Andrew - BBS
mTOR, Metabolism, and Cancer
Advisor: John Blenis

Chou, Michael - BBS
Algorithms for the analysis of biological sequence data
Advisor: George Church

Christensen, Adam - NSCI
The Role of TRP Channels in Mechanosensation
Advisor: David Corey

Cornejo, Melanie - IMM
Novel Roles of NOTCH and JAK3 During Normal and Malignant Hematopoiesis
Advisor: D. Gary Gilliland

Costantino, Cristina - IMM
The class II MHC processing and presentation pathway in human CD4+ T cells
Advisor: David Hafler

Dermody, Jessica - BBS
Identification of novel functions of the Paf1C and Npl3 during RNA polymerase II transcription elongation
Advisor: Stephen Buratowski

Djuretic, Ivana - IMM
Regulation of gene expression in T lymphocytes by the transcription factor Runx3
Advisor: Anjana Rao

Dong (Shore), Carolyn - BBS
The essential role of the mitochondrial electron transport chain in Plasmodium falciparum
Advisor: Dyann Wirth

Dougan, Michael - IMM
Balancing Oncogenic Inflammation and Anti-Tumor Immunity in the Development of Novel Immune Therapies for Cancer
Advisor: Glenn Dranoff

Dovey, Michael - BBS
Genetic analysis of vertebrate cell cycles and melanoma in zebrafish
Advisor: Leonard Zon

Erlandson, Karl - VIR
Interactions of the SecY Channel and the SecA ATPase with a Translocating Polypeptide
Advisor: Tom Rapoport

Farny, Natalie - BBS
REGULATING MRNA METABOLISM: ALTERNATIVE SPLICING, NUCLEAR MRNA EXPORT, AND TRANSLATIONAL CONTROL
Advisor: Pamela Silver

Fassett, Marlys - IMM
The Nur77 family in T cell tolerance
Advisor: Christophe Benoist

Faulkner, Melinda - BBS
Functional plasticity of alkyl hydroperoxide reductase
Advisor: Jonathan Beckwith

Fixen, Kathryn - BBS
Characterization of factors mediating localization of the Shigella actin assembly protein IcsA to the bacterial pole
Advisor: Marcia Goldberg

Flavell, Steven - NSCI
Regulation of synapse development by the activity-regulated transcription factor MEF2
Advisor: Michael Greenberg

Gajdos, Zofia - BBS
Genetic analysis of the timing of human puberty
Advisor: Joel Hirschhorn

Ge, Xuecai - NSCI
Functions of the Centrosome in Embryonic Neurogenesis
Advisor: Li-Huei Tsai

Gonzalez, Mark - BBS
Interactions in a multi-protein complex required for bacterial cell division
Advisor: Jonathan Beckwith

Gouwens, Nathan - NSCI
Processing of Neural Signals in the Drosophila Olfactory System
Advisor: Rachel Wilson

Hollstein, Pablo - BBS
Proteasomal regulation of the NF1 tumor suppressor and Ras signaling
Advisor: Karen Cichowski

Hong, Elizabeth - NSCI
Functional Significance of Neuronal Activity-Dependent Transcriptional Regulation in the Nervous System
Advisor: Michael Greenberg

Hunter, John - NSCI
Spatial Integration of Motion Signals in Macaque MT
Advisor: Richard Born

Hurt, Jessica - BBS
SYSTEMS AND TARGETED ANALYSES OF mRNA EXPORT IN METAZOANS
Advisor: Pamela Silver

Iweala, Onyinye - BBS
The enterohepatic microenvironment modulates immune responses to vaccination
Advisor: Cathryn Nagler

Jeanson, Nathaniel - BBS
Metabolic Regulation of Hematopoietic Stem Cells
Advisor: David Scadden

Johnson, Karen - VIR
THE INHIBITION OF TYPE I INTERFERON SIGNALING BY HERPES SIMPLEX VIRUS 1
Advisor: David Knipe

Kennedy, Caleb - BBS
Multidimensional analysis of cellular regulation in perturbed metabolic systems
Advisor: Pamela Silver

Koo, Sumin - BBS
The Role of Caudal Genes in Adult Hematopoiesis and Leukemogenesis
Advisor: D. Gary Gilliland

Kovtun, Misao - NSCI
Characterization of an Importin beta11 Mutant at the Drosophila Neuromuscular Junction
Advisor: Thomas Schwarz

Kreslavskiy, Taras - IMM
Developmental divergence and functional convergence of alpha beta and gamma delta T cell lineages
Advisor: Harald von Boehmer

Laird, Melissa - VIR
HIV/SIV VARIABLE LOOPS AS TARGETS AND ELICITORS OF ANTIBODIES THAT NEUTRALIZE VIRAL INFECTIVITY
Advisor: Ronald Desrosiers

Lebensohn, Andres - BBS
Biochemical studies on the regulation of actin assembly by N-WASP and WAVE protein complexes
Advisor: Marc Kirschner

LeBleu, Valerie - BBS
The Pathobiochemistry of Alport Syndrome and Mechanism of Cell-Based Therapy
Advisor: Raghu Kalluri

Lee, Jennifer - BBS
Post-translational Modification and Regulation of Phosphoinositide 3-Kinase
Advisor: Lewis Cantley

Libedinsky, Camilo - NSCI
Neuronal Mechanisms of Visual Perception Role of Early Visual and Prefrontal Cortical Areas in Conscious Awareness
Advisor: Margaret Livingstone

Maliszewski, Laura - VIR
The Role of miRNAs in HIV Infection of Primary Macrophages
Advisor: Judy Lieberman

McLaughlin, Katherine - IMM
Antibodies to MOG in adult and pediatric demyelinating diseases
Advisor: Kai Wucherpfennig

Morris, Zachary - BBS
Regulation of EGFR by the NF2 Tumor Suppressor, Merlin
Advisor: Andrea McClatchey

Mosca, Timothy - NSCI
Nuclear Import and Synapse to Nucleus Signalling at the Drosophila Neuromuscular Junction
Advisor: Thomas Schwarz

Mowrer, Karen - BBS
Alternative Splicing Of BACE1 Pre-mRNA And Its Implications For Alzheimer Disease
Advisor: Michael Wolfe

Naveiras Torres-Quiroga, Olaia - BBS
Novel Determinants of the Hematopoietic Microenvironment in Development and Homeostasis
Advisor: George Daley

Naylor, Maria - BBS
Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork
Advisor: Stephen Elledge

Ng, Samuel - IMM
Ikaros and Mi-2beta mediated hematopoietic lineage determination
Advisor: Katia Georgopoulos

Nhek, Sokha - BBS
Protein Kinase D Signaling Through Substrate Phosphorylation
Advisor: Alex Toker

Nunes, Paula - BBS
Exploring Regulated Membrane Protein Trafficking of the Aquaporin-2 Water Channel in Renal Epithelial Cells
Advisor: Dennis Brown

Oh, Sungwhan - BBS
Life of Resolvins: Synthesis, bioactions and metabolic inactivation of novel anti-inflammatory and pro-resolving mediators
Advisor: Charles Serhan

Ozsolak, Fatih - BBS
Integrated Epigenomics Analyses to Understand MicroRNA Transcriptional Regulation
Advisor: David Fisher

Potenta, Scott - BBS
Endothelial-to-Mesenchymal Transition in Cancer Progression and Tissue Fibrosis
Advisor: Raghu Kalluri

Ramdya, Pavan - NSCI
Direction selectivity in the larval zebrafish optic tectum
Advisor: Florian Engert

Rappley, Irit - NSCI
Selective Effects of Alpha-Synuclein on Membrane Phospholipids and Mitochondrial Function
Advisor: Dennis Selkoe

Roberts, Kristina - BBS
Mutation of a Novel Non-Coding RNA Causes Vestibular Malformation in the Epistatic circler Mouse
Advisor: Nancy Andrews

Rompani, Santiago - BBS
Lineage tracing in the vertebrate CNS: neuronalsubtype specification and a shared lineage for astrocytes and oligodendrocytes
Advisor: Constance Cepko

Rud, Debrah - VIR
Identification of FAM111A as a Novel Simian Virus 40 Large T Antigen Binding Protein that Affects Viral Host Range
Advisor: James DeCaprio

Sankaran, Vijay - BBS
Molecular Mechanisms of Erythropoiesis and Globin Gene Regulation
Advisor: Stuart Orkin

Schlabach, Michael - BBS
High throughput genetic screens in mammalian cells
Advisor: Stephen Elledge

Sero, Julia - BBS
Integrated Mechanochemical Control of Directional Cell Migration Through Paxillin
Advisor: Donald Ingber

Silva, Laurie - VIR
The Roles of Phosphorylation and the Carboxy-terminus in the Function of the Human Cytomegalovirus Processivity Factor, UL44
Advisor: Don Coen

Sims, Jennifer - BBS
Transcriptional activity and regulation of gene expression during the intraerythrocytic developmental cycle of Plasmodium falciparum
Advisor: Dyann Wirth

Songnuan, Wisuwat - BBS
Studies of Pathogen Defense in Arabidopsis Roots
Advisor: Frederick Ausubel

Sullivan, Nora - BBS
Chromosome Dynamics in Bacillus subtilis
Advisor: David Rudner

Svendsen, Jennifer - BBS
The SLX4/BTBD12 complex: a molecular toolkit for DNA repair
Advisor: J.Wade Harper

Tahiliani, Mamta - IMM
Chromatin-modifying enzymes of the 2-oxoglutarate and Iron(II)-dependent oxygenase superfamily
Advisor: Anjana Rao

Tanner, Geoffrey - NSCI
K(ATP) Channels, Metabolism, and Neuronal Excitability
Advisor: Gary Yellen

Thompson, Cheryl - BBS
Signaling mechanisms that control presynaptic morphogenesis at the Drosophila neuromuscular junction
Advisor: David Van Vactor

Tischfield, Max - NSCI
Human eye movement disorders help identify molecular and genetic etiologies of novel neurological syndromes
Advisor: Elizabeth Engle

Troy, Erin - BBS
Microbial colonization shifts the Vbeta repertoire of intestinal T cells and polysaccharide expression in the microbiota
Advisor: Dennis Kasper

Turner, Devin - IMM
Biology of Fc(epsilon)RI expression on plasmacytoid dendritic cells
Advisor: Jean-Pierre Kinet

Viswanathan, Srinivas - BBS
Lin28: An Inhibitor of microRNA Biogenesis with Roles in Cancer and Development
Advisor: George Daley

West, Jason - BBS
Modeling Primordial Germ Cell Formation In Vitro
Advisor: George Daley

Yi, Caroline - BBS
Genetic and Biochemical Approaches Reveal Integration of Metabolism and Apoptosis
Advisor: Junying Yuan

Zappaterra, Mauro - BBS
Analysis of Cerebrospinal Fluid in Brain Development
Advisor: Christopher Walsh

Zhang, Dan (Phoebe) - BBS
Noncatalytic Effect of the Ubiquitin Ligase Hul5 on Proteasome Function
Advisor: Daniel Finley

2008

Adamovich, David - BBS
Activating Mutations of N-WASP Reveal Novel Roles for N-WASP During Shigella Infection
Advisor: Scott Snapper

Agosto, Melina - BBS
Reovirus outer-capsid disassembly and the mechanism of membrane penetration
Advisor: Max Nibert

Albeanu, Dinu - NSCI
Multimodal Imaging of Sensory Inputs and Neuronal Coding in the Rodent Olfactory Bulb
Advisor: Venkatesh Murthy

Arroyo, Jason - BBS
Protein phosphatase 2A complexes and human cell transformation
Advisor: William Hahn

Asthana, Saurabh - BBS
Rehabilitating Junk DNA
Advisor: Shamil Sunyaev

Bakalarski, Corey - BBS
Understanding Protein Regulation through Novel Computational Approaches to High-Throughput Proteome Analysis
Advisor: Steven Gygi

Balibar, Carl - BBS
Intercepting Intermediates in Amino Acid-Derived Natural Product Biosynthesis
Advisor: Christopher T Walsh

Berg, James - NSCI
Imaging Neuronal Metabolism
Advisor: Gary Yellen

Boutwell, Christian - VIR
INVESTIGATION OF THE ADAPTATION OF HIV-1C TO THE HOST CTL IMMUNE RESPONSE
Advisor: Myron Essex

Bowman, John - VIR
Characterization of Expression of the Herpes Simplex Virus Type-1 ICP22 and Us1.5 Proteins
Advisor: Priscilla Schaffer

Brown, Christopher - BBS
TRANSCRIPTIONAL REGULATION AT THE NUCLEAR PORE COMPLEX
Advisor: Pamela Silver

Brown, Kerry - BBS
Identification of Auditory Genes and Regulatory Elements Using a Cytogenetic Approach
Advisor: Cynthia Morton

Buchberger, Johannes - BBS
The role of Sir3 in spreading of silent chromatin in Saccharomyces cerevisiae
Advisor: Danesh Moazed

Burrack, Laura - BBS
Host cell factors involved in the vacuolar biology of Listeria monocytogenes infection
Advisor: Darren Higgins

Butler, Maurice - BBS
Negative Regulation of RNA Interference in Caenorhabditis elegans
Advisor: Gary Ruvkun

Butty, Vincent - IMM
A population genetics analysis of the human T cell costimulatory locus in Type 1 Diabetes
Advisor: Christophe Benoist

Ch'ng, Yeang - NSCI
Functional Imaging of Cellular and Vascular Activity in Visual Cortex
Advisor: R. Clay Reid

Cheung, Vanessa - BBS
Investigation of transcription initiation from cryptic promoter sites in Saccharomyces cerevisiae
Advisor: Fred Winston

Choi, Andrew - BBS
Dimer Stabilization and Aggregation of Superoxide Dismutase
Advisor: Peter Lansbury

Chun, Denise - BBS
Regulators of AMPA-Type Glutamate Receptor Trafficking in C. elegans
Advisor: Joshua Kaplan

Colodner, Kenneth - NSCI
Using Drosophila to investigate the glial contribution to neurodegenerative disorders
Advisor: Mel Feany

Cotner, Elizabeth - BBS
Structure and Mechanism of Human DNA Ligase III, An Essential Repair Enzyme
Advisor: Tom Ellenberger

Cruz-Guilloty, Fernando - BBS
Transcriptional and epigenetic regulation of CD8+ T cell differentiation and function
Advisor: Anjana Rao

Cureton, David - VIR
VIRAL AND CELLULAR DETERMINANTS OF VESICULAR STOMATITIS VIRUS ENTRY
Advisor: Sean Whelan

DiPietrantonio, Heather - BBS
Toward understanding how mossy fiber neuron diversity in the brain stem is generated
Advisor: Susan Dymecki

Do, Michael - NSCI
Generation and Regulation of Pacemaking in Subthalamic Neurons
Advisor: Bruce Bean

Dodson, Allen - BBS
Screening for Novel, Stage-Specific Inhibitors of Herpes Simplex Virus Replication
Advisor: Don Coen

Dudnik, Nina - BBS
Histone dimers on the move: Nucleosome assembly systems for H2A and H2AV in Drosophila
Advisor: Kami Ahmad

Fontaine Rider, Errin - VIR
HERPES SIMPLEX VIRUS IMMEDIATE EARLY PROTEINS AND EFFECTS ON TRANSLATION
Advisor: David Knipe

Frank, Christopher - BBS
Regulated ATF4 persistence in cell cycle control and neurogenesis
Advisor: Li-Huei Tsai

Gabel, Harrison - BBS
Genetic analysis of small RNA-mediated gene silencing in C. elegans
Advisor: Gary Ruvkun

Garcia, Maria - VIR
The molecular basis of Herpesvirus Saimiri oncogenicity
Advisor: Jae Jung

Gierahn, Todd - BBS
The T cell response to Chlamydia trachomatis: Identification of new antigens and characterization of their presentation
Advisor: Darren Higgins

Greer, Paul - BBS
Molecular mechanisms underlying synapse development: From axon guidance to synapse formation
Advisor: Michael Greenberg

Groen, Aaron - BBS
Chromatin Dependent Microtubule Assembly During Meiosis
Advisor: Timothy Mitchison

Haushofer, Johannes - NSCI
Cortical Object Representations
Advisor: Margaret Livingstone

Henrickson, Sarah - IMM
Dynamics of T cell activation in vivo
Advisor: Ulrich von Andrian

Hsu, Jeanne - BBS
Mechanisms Coupling Steps in Gene Expression
Advisor: Robin Reed

Huang, I-Chueh - VIR
ENZYMATIC REGULATION OF VIRAL ENTRY
Advisor: Michael Farzan

Hutti, Jessica - BBS
Characterization of Inflammatory Signaling Networks
Advisor: Lewis Cantley

Hyde, Rhonda - NSCI
Genetic Analysis of Protein Kinase C and MAPK in C. elegans mechanosensation
Advisor: Anne Hart

Ivanovic, Tijana - VIR
From Virion to Viral Factory: Reovirus Particle Transformations Leading to Cell Entry and Productive Infection
Advisor: Max Nibert

Johannessen, Cory - BBS
Exploiting neurofibromatosis type 1-associated cancer models to identify novel therapeutic targets
Advisor: Karen Cichowski

Kamberov, Yana - BBS
Mechanisms of Halofuginone Activity
Advisor: Malcolm Whitman

Kerr, Monica - BBS
Proteomic Screen Identifies Novel Phosphatidylinositol 3,4-bisphosphate Binding Protein
Advisor: Lewis Cantley

Korol, Oksana - BBS
Dkk1 domains in heart induction and axial development in Xenopus laevis
Advisor: Mark Mercola

Koundakjian, Edmund - NSCI
An analysis of the development of the cochlear-vestibular ganglion
Advisor: Lisa Goodrich

Kushnir, Anna - VIR
THE EFFECT OF CELLULAR STRESS-INDUCED FACTORS ON HSV-1 GENE EXPRESSION AND REPLICATION
Advisor: Priscilla Schaffer

Lamming, Dudley - BBS
The regulation of lifespan by sirtuins in Saccharomyces cerevisiae
Advisor: David Sinclair

Lan, Fei - BBS
Dynamic Regulation of Histone Lysine Methylation
Advisor: Yang Shi

Lee, Yang - BBS
Regulating the Ribonucleotide Reductase Pathway in S. cerevisiae Through Nuclear Retention and Import Mechanism
Advisor: Stephen Elledge

Leed, Alison - BBS
Structure Determination and Interaction Studies of the Human Gamma-Glutamylcysteine Synthetase Light Subunit by Nuclear Magnetic Resonance
Advisor: Gerhard Wagner

Li, Ju-Mei - BBS
Cellular responses that preserve genome stability in S. cerevisiae
Advisor: Stephen Elledge

Li, Qianru - BBS
SYSTEMATIC ANALYSES OF INTERACTOME NETWORKS
Advisor: Marc Vidal

Libuda, Diana - BBS
Identification and characterization of histone gene amplification as a method for dosage compensation in Saccharomyces cerevisiae
Advisor: Fred Winston

Lu, Alice - NSCI
Potential Roles for Ubiquilin 1 in Alzheimer's Disease Pathogenesis
Advisor: Rudolph Tanzi

Lu, Ju - NSCI
Connectomic Studies of the Mammalian Neuromuscular System
Advisor: Jeff Lichtman

Manuel, Edwin - VIR
Immunodominance in Primate Immunodeficiency Virus Infection
Advisor: Norman Letvin

McGillicuddy, Lauren - BBS
Regulation and function of the NF1 tumor suppressor
Advisor: Karen Cichowski

Mirchandani, Kanchan - VIR
A role for the Fanconi Anemia pathway in error-prone DNA damage tolerance
Advisor: Alan D'Andrea

Nguyen, Christine - VIR
CENTROSOMAL AND MITOTIC ABERRATIONS: MECHANISTIC INSIGHTS INTO HPV16 E7 ONCOPROTEIN-INDUCED GENOMIC DESTABILIZATION
Advisor: Karl Münger

Olsen, Shawn - NSCI
Synaptic and Circuit Mechanisms of Odor Processing in Drosophila
Advisor: Rachel Wilson

Onishi-Seebacher, Megumi - BBS
The Role of Nucleosomes in Heterochromatin Assembly in Saccharomyces cerevisiae
Advisor: Danesh Moazed

Ooi, Liang Yee - BBS
The role of microcephalin in cell cycle regulation and embryonic development
Advisor: Marc Kirschner

Parmar, Kush - BBS
Kruppel-like factor 2 as a Central Link Between Blood Flow and Vascular Endothelial Function
Advisor: Guillermo Garcia-Cardeña

Patel, Vishal - BBS
Small Molecule Inhibitors of Plasmodium falciparum
Advisor: Jon Clardy

Poling, Laura - BBS
Dysregulation of the MiT family of transcription factors in melanoma
Advisor: David Fisher

Pollington McGehee, Annette - BBS
Class II MHC trafficking and XBP-1 in immune cells
Advisor: Hidde Ploegh

Ponce, Carlos - NSCI
Integrating Visual Information Through Parallel Pathways
Advisor: Richard Born

Possemato, Richard - BBS
The interface between telomerase, the telomere and replicative senescence
Advisor: William Hahn

Radoshitzky, Sheli - VIR
CELL ENTRY OF NEW WORLD HEMORRHAGIC FEVER ARENAVIRUSES
Advisor: Michael Farzan

Runner, Vanessa - BBS
Function of the Rpb4 Subunit of RNA Polymerase II during Transcription
Advisor: Stephen Buratowski

Scott, Jamil - BBS
Tissue Interactions and Molecular Factors Involved in Indifferent Gonad Specification in the Avian Embryo
Advisor: Thomas Schultheiss

Shankar, Ganesh - NSCI
Soluble Abeta Oligomers and Synaptic Dysfunction in Alzheimer's Disease
Advisor: Dennis Selkoe

Shaw, Christine - BBS
T cell responses induced by bacterial toxin fusion proteins
Advisor: Michael Starnbach

Simon, David - NSCI
microRNA Regulation of Synapse Function in C.elegans
Advisor: Joshua Kaplan

Singh, Gitanjali - BBS
Examination of the final steps in the biosynthesis of Syringomycin E
Advisor: Christopher T Walsh

Sogah, Dodzie - BBS
Molecular Mechanisms of Crosstalk between Apoptotic and Metabolic Regulation
Advisor: Junying Yuan

Soohoo, Christina - BBS
Structure and Function of the Telomerase Inhibitor PinX1
Advisor: Kun Ping Lu

Spencer, Rebecca - BBS
Identification of an Xist RNA binding protein and a novel genetic element at the X inactivation center
Advisor: Jeannie Lee

Sural, Tuba - BBS
The role of MSL3 in Drosophila dosage compensation
Advisor: Mitzi Kuroda

Swinburne, Ian - BBS
Dynamic and Temporal Aspects of RNA Production and Processing
Advisor: Pamela Silver

Tam, Vincent - BBS
Characterization of the Type III Secretion System in non-O1, non-O139 strains of Vibrio cholerae
Advisor: John Mekalanos

Trask, Shane - VIR
The mechanism of membrane penetration by rotavirus
Advisor: Stephen Harrison

Tulpule, Asmin - BBS
Congenital disease-specific human embryonic stem cells reveal developmental defects in the hematopoietic lineage
Advisor: George Daley

Valencia, Patricia - BBS
Splicing promotes mRNA export in mammalian cells
Advisor: Robin Reed

Vashlishan, Amy - BBS
Identification and Characterization of Genes that Regulate GABA Synapses
Advisor: Joshua Kaplan

Wang, Jian - BBS
Characterization of the tumor suppressor PTEN in zebrafish
Advisor: Thomas Roberts

Wass, Amanda - VIR
BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF THE VPg URIDYLYLATION COMPLEX OF POLIOVIRUS
Advisor: James Hogle

Werneck, Miriam - IMM
Transcriptional regulation of normal and neoplastic leukocyte physiology: a closer look at Snf5 and T-bet in cancer
Advisor: Harvey Cantor

Williams, Benjamin - BBS
Somatic Homolog Pairing in Drosophila Cell Culture
Advisor: Chao-ting Wu

Williams, Grace - BBS
Identification and characterization of critical phosphorylations required for Bub1 function
Advisor: Thomas Roberts

Wojiski, Sarah - BBS
Regulation of self-renewal by leukemogenic mutations associated with acute promyelocytic leukemia
Advisor: D. Gary Gilliland

Woodworth, Joshua - IMM
Class I MHC-Restricted CD8+ T cells and Host Immunity to Mycobacterium tuberculosis
Advisor: Samuel Behar

Wu, Su - VIR
YY1 functions in homologous recombination DNA repair and mice spermatogenesis
Advisor: Yang Shi

Xu, Lai - BBS
FUNCTIONAL ANALYSIS OF CULLIN-BASED UBIQUITIN LIGASE AND A NOVEL UBC DOMAIN-CONTAINING PROTEIN
Advisor: J.Wade Harper

Xu, Lei - BBS
A study of the mechanism and method to control the degradation of Mad1 by regulating ubiquitin ligase activity of c-IAP1
Advisor: Junying Yuan

Zhou, Zhe - BBS
Carrier Protein Tailoring, Recognition, and Applications for Protein Labeling
Advisor: Christopher T Walsh

2007

Anderson, Sarah - BBS
Post-Translational Regulation of TGF-b Superfamily Ligands in Skeletal Muscle and During Xenopus Embryogenesis
Advisor: Malcolm Whitman

Arnold, Michelle - VIR
Roles of muNS in Reovirus Factory Formation
Advisor: Max Nibert

Bajmoczi, Milan - BBS
Internalization of Pseudomonas aeruginosa by Non-polarized and Polarized Epithelial Cells: a CFTR- and Caveolin-1-dependent Process
Advisor: David Golan

Beausoleil, Sean - BBS
Large-scale Analysis of Protein Phosphorylation
Advisor: Steven Gygi

Bikoff, Jay - NSCI
Molecular mechanisms regulating cortical development: From neurons to synapses
Advisor: Michael Greenberg

Boehm, Jesse - BBS
Experimental models of transformation as platforms for oncogene discovery
Advisor: William Hahn

Bryant, Kevin - VIR
REGULATION OF TRANSLATION DURING HERPES SIMPLEX VIRUS-1 INFECTION
Advisor: Don Coen

Call, Matthew - IMM
Intramembrane Organization of T Cell Receptor-CD3 Complex Assembly
Advisor: Kai Wucherpfennig

Campbell, Catarina - BBS
Implications of population structure and regulatory variation for genetic association studies
Advisor: Joel Hirschhorn

Chan, Betty - BBS
Functional Studies of the Calcineurin-DSCR1 Complex
Advisor: Tom Ellenberger

Chao, Wendy - BBS
IGF2: Epigenetic Regulation and Role in Development and Disease
Advisor: Patricia D'Amore

Chen, Adrienne - VIR
Epstein-Barr Virus Nuclear Antigen 3B- and 3C-regulated cellular genes in virus-immortalized B cells
Advisor: Fred Wang

Christofk, Heather - BBS
The M2 Splice Isoform of Pyruvate Kinase is a Phosphotyrosine Binding Protein Critical for Tumor Cell Metabolism and Proliferation
Advisor: Lewis Cantley

Chung, Eunju - NSCI
Axonal Transport of Synaptic Components and Synaptogenesis in Drosophila
Advisor: Thomas Schwarz

Ciccone, David - IMM
The epigenetic regulation of V(D)J recombination: chromatin architecture and the insulator protein, CTCF
Advisor: Marjorie Oettinger

Cole, Banumathi - BBS
Membrane Distribution of the Nf2 Tumor Suppressor, Merlin
Advisor: Andrea McClatchey

Colmenares, Serafin - BBS
The Mechanism of RNAi Assembly and siRNA Generation in Fission Yeast Centromeres
Advisor: Danesh Moazed

Cui, Can - BBS
Herpes Simplex Virus DNA Replication and MicroRNA Expression: Molecular Pharmacological, Computational, and Genetic Approaches
Advisor: Don Coen

Dobi, Krista - BBS
Upstream Activation Sequence Function in Saccharomyces cerevisiae: the Potential for Long Distance Transcriptional Activation and the Role of Sin4
Advisor: Fred Winston

Dougan, Stephanie - IMM
The role of MTP in CD1d antigen presentation and NKT cell development
Advisor: Richard Blumberg

Dunfee, Rebecca - VIR
ENVELOPE-RECEPTOR INTERACTIONS OF NEUROTROPIC HIV
Advisor: Dana Gabuzda

Elson-Schwab, Ilan - BBS
Mechanisms Underlying Ab- and Tau-Induced Neuronal Degeneration in Alzheimer's Disease
Advisor: Mel Feany

Field, Christine - BBS
Genetic and Biochemical Studies of Cytokinesis
Advisor: Marc Kirschner

Friedman, Adam - BBS
Genomic dissection of receptor tyrosine kinase activation of extracellular signal-regulated kinase in Drosophila
Advisor: Norbert Perrimon

Frietze, Seth - BBS
GENOME-WIDE ANALYSIS OF THE COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE CARM1 IN BREAST CANCER CELLS
Advisor: Pamela Silver

Garibyan, Lilit - BBS
The Role of TACI Mutations in Common Variable Immunodeficiency
Advisor: Raif Geha

Gopal, Raj - NSCI
Regulation of DNA Double-Strand Break Repair by Parkin
Advisor: Bruce Yankner

Gurtan, Allan - BBS
Characterization of a Novel E3 Ubiquitin Ligase in Fanconi Anemia
Advisor: Alan D'Andrea

Harrar, Dana - NSCI
An RNA Interference Screen Identifies New Molecules Required for Mammalian Synapse Development
Advisor: Michael Greenberg

Hass, Matthew - NSCI
Identification of Novel Roles of the Amyloid Precursor Protein in Signal Transduction
Advisor: Bruce Yankner

Hathaway, Nathaniel - BBS
Mechanism of APC Catalyzed Ubiquitination of Cyclin B1 and Analysis of Degradative Role of Ubiquitin Linkage
Advisor: Randall King

He, Xi - VIR
Regulation of SNF2h Chromatin Remodeling Activity
Advisor: Robert Kingston

Hemming, Matthew - NSCI
Regulation of Amyloid b-Protein Levels by Proteolytic Degradation and its Implications for Alzheimer's disease
Advisor: Dennis Selkoe

Herrington, Todd - NSCI
Attentional Shifts in Parietal Cortex and Behavior
Advisor: John Assad

Ho, Diana - BBS
The role and regulation of TGF-b signaling during Xenopus regeneration and development
Advisor: Malcolm Whitman

Hooks, Bryan - NSCI
Functional Development of the Retinogeniculate Synapse
Advisor: Gina Turrigiano

Huang, Franklin - BBS
The role of hemojuvelin in systemic iron homeostasis
Advisor: Nancy Andrews

Hughes, Michael - NSCI
A Genetic and Biochemical Analysis of Dscam Signaling in Dendrite Morphogenesis
Advisor: Dietmar Schmucker

Hunter, Nina - BBS
Redefining the dorsal hindbrain based on genetic lineage
Advisor: Susan Dymecki

Ichida, Justin - BBS
In Vitro Selection Systems for TNA
Advisor: Jack Szostak

Kattenhorn, Lisa - VIR
Identification and Characterization of a Novel Deubiquitinating Activity Conserved Within the Herpesvirus Large Tegument Proteins
Advisor: Hidde Ploegh

Khoo, Christine - BBS
Adaptive Responses of Oncogenic Cells to Dysfunctional Telomeres
Advisor: Ronald DePinho

Kim, Dohoon - BBS
Insights into Neurodegeneration from p25/cdk5
Advisor: Li-Huei Tsai

Kontopoulos, Eirene - NSCI
Mechanisms of a-synuclein Neurotoxicity in Parkinson's Disease
Advisor: Mel Feany

Koralov, Sergei - IMM
Role of Secondary IgH Rearrangements in B Cell Ab Repertoire
Advisor: Klaus Rajewsky

Koralova, Anne - BBS
Trans interactions at the yellow gene in Drosophila melanogaster
Advisor: Chao-ting Wu

Latorre-Esteves, Magda - BBS
Characterization of the Saccharomyces cerevisiae sirtuin family and their roles in lifespan regulation.
Advisor: David Sinclair

Leibman, Mark - BBS
Modulation of promoter escape by s-core interactions of the bacterial RNA polymerase holoenzyme
Advisor: Ann Hochschild

Leptos, Kyriacos - BBS
Computational Tools for Peptide Quantification Using Mass Spectrometry and Their Application to the Proteome of Prochlorococcus marinus MED4
Advisor: George Church

Li, Juying - BBS
Characterization of the Role of Caspase-11 in Regulating Actin Dynamics and Cell Migration
Advisor: Junying Yuan

Lichtenstein, Jamie - BPH
Mouse Strain Differences Influence Pulmonary Responses to Stachybotrys chartarum
Advisor: Joseph Brain

Link, Malen - VIR
MECHANISM OF EXPRESSION AND FUNCTIONAL ANALYSIS OF HERPES SIMPLEX VIRUS TYPE-1 PROTEINS OBPC-1 AND OBPC-2
Advisor: Priscilla Schaffer

Liou, Kwa - BBS
A chemical genetic screen to identify small molecule inhibitors of HPV E6-mediated p53 degradation.
Advisor: Peter Howley

Liu, Zhenning - BBS
The role of PI3K p110a and p110b isoforms in oncogenesis
Advisor: Thomas Roberts

Maharaj, Arindel - BBS
VEGF IS REQUIRED FOR VASCULAR AND TISSUE HOMEOSTASIS
Advisor: Patricia D'Amore

Malecki, Michael - BBS
The Notch Negative Regulatory Region: Mutations and Mechanisms
Advisor: Stephen Blacklow

Marcotte, Laura - BBS
STRUCTURAL AND BIOCHEMICAL STUDIES OF THE POLIOVIRUS PRECURSOR PROTEIN 3CD AND THE COMPONENTS OF THE VIRAL REPLICATION COMPLEX
Advisor: James Hogle

Matthews, Adam - IMM
Regulatory mechanisms in V(D)J recombination
Advisor: Marjorie Oettinger

McEwen, Jason - BBS
Trafficking of Synaptic Proteins and Tomosyn inhibits Synaptic Vesicle Priming
Advisor: Joshua Kaplan

McKee, Adrienne - BBS
Systems analysis of RNA-binding proteins and regulated mRNA processing
Advisor: Pamela Silver

Meray, Robin - BBS
Biochemical and cell biological studies of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1
Advisor: Peter Lansbury

Ow, Yong-Ling - IMM
Investigating the metabolism of tumours with an in silico chemical genetics approach
Advisor: Stuart Schreiber

Paffett-Lugassy, Noëlle - BBS
Hematopoiesis and angiogenesis in the zebrafish
Advisor: Leonard Zon

Perron, Michel - VIR
TRIM5ahu: An Innate Cellular Defense Against N-tropic Murine Leukemia Virus Infection in Humans
Advisor: Joseph Sodroski

Porreca, Gregory - BBS
Multiplex Polony Sequencing for Analysis of Genomes, Transcriptomes, and Exonomes
Advisor: George Church

Redd, Andrew - VIR
Human Immunodeficiency Virus Type 1 Subtype C and Hematopoiesis
Advisor:

Rivera-Feliciano, José - BBS
Genetic regulation of heart-valve development
Advisor: Clifford Tabin

Roan, Nadia - BBS
Antigen-specific T cell responses to Chlamydia trachomatis
Advisor: Michael Starnbach

Rohas, Lindsay - BBS
A Fundamental System of Cellular Energy Homeostasis Regulated by PGC-1a
Advisor: Bruce Spiegelman

Safo, Patrick - NSCI
THE ROLE OF ENDOCANNABINOIDS IN SYNAPTIC PLASTICITY AT THE GRANULE CELL TO PURKINJE CELL SYNAPSE
Advisor: Wade Regehr

Schwabish, Marc - BBS
Asf1 and Swi/Snf Function in RNA Polymerase II Elongation and Histone Dynamics
Advisor: Kevin Struhl

Shakhnovich, Elizabeth - BBS
Small molecules as novel probes for understanding Vibrio cholerae virulence mechanisms and regulation in vitro and in vivo
Advisor: John Mekalanos

Shao, Yu - BBS
Regulation of axon guidance and dendritic spine development by Vav family GEFs
Advisor: Michael Greenberg

Shen, Aimee - BBS
Transcriptional repression, anti-repression, and glycosylation in the regulation of flagellar motility in Listeria monocytogenes
Advisor: Darren Higgins

Smith, Donald - BBS
The role of innate immune signaling in generating tolerance and immunity to orally administered antigens
Advisor: Cathryn Nagler

Soler-Llavina, Gilberto - NSCI
Compartmentalization and modulation of synaptic signaling in dendrites and spines
Advisor: Bernardo Sabatini

Soriano, Michelle - BBS
Regulation of STAT Signal Transduction by Posttranslational Modifications
Advisor: Michael Grusby

Stover, Elizabeth - BBS
FIP1L1-PDGFRalpha, a tyrosine kinase fusion protein involved in chronic eosinophilic leukemia
Advisor: D. Gary Gilliland

Teer, Jamie - BBS
Function of Replication Initiation Proteins ORC and Cdt1
Advisor: Anindya Dutta

Tomov, Vesselin - BBS
Codon-Optimized and Reporter-Packaging Strains of HIV-1
Advisor: Brian Seed

Tothova, Zuzana - BBS
The Role of Forkhead Transcription Factors in Hematopoiesis and Leukemogenesis
Advisor: D. Gary Gilliland

Vanderspurt, Cecily - BBS
Post-Transcriptional Control of Cholera Toxin and Factors Affecting the Virulence of V. cholerae
Advisor: Stephen Calderwood

Vijayan, Sujith - NSCI
Characterization of Activity in the Primary Somatosensory Cortex During Active Behavior and Sleep
Advisor: Emery Brown

Villaseñor, Jennifer - IMM
The repertoire of Aire-regulated peripheral tissue antigens in single thymic medullary epithelial cells
Advisor: Diane Mathis

Wai-Huang, Stephanie - BBS
Regulation of the Rho GTPase Cdc42 During Cell Polarization in Budding Yeast
Advisor: Rong Li

Wein, Marc - IMM
Regulation of Immunobiology and Skeletal Biology by the Zinc Finger Adaptor Protein Schnurri-3
Advisor: Laurie Glimcher

Wong, Jamie - IMM
The life of the regulatory T cell repertoire
Advisor: Christophe Benoist

Wrighting, Diedra - BBS
Transcriptional Regulation of Hepcidin, a hormone that maintains iron homeostasis
Advisor: Nancy Andrews

Xu, Na - BBS
The Mechanism of Homologous Interaction at the X-Inactivation Center
Advisor: Jeannie Lee

Xu, Qing - BBS
Discovery of modifiers and biomarkers for prostate cancer
Advisor: William Sellers

Yang, Annie - BBS
Transcriptional Targets and Functional Activities of the p53 Gene Family
Advisor: Kevin Struhl

Yoder, Joshua - VIR
Molecular Rearrangements of Recombinant and Authentic Rotavirus VP5*
Advisor: Phil Dormitzer

2006

Agopian, Kristin - VIR
Characterization of Primary HIV-1 NEF Alleles and Their Association with P21-Activated Kinase 2
Advisor: Dana Gabuzda

Ardayfio, Paul - NSCI
Behavioral Investigation of Cognitive Function in Mouse Models of Neurological and Psychiatric Disorders
Advisor: Kwang-Soo Kim

Arias- Foley, Emily - BBS
Replication-dependent destruction of Cdt1 restricts DNA replication to once per cell cycle
Advisor: Johannes Walter

Aron, Kathryn - BBS
Genetic and Genomic Studies of Ubiquitin-Proteasome System Activities
Advisor: Pamela Silver

Ayala, Ramses - BBS
Nudel, a multifaceted cytoskeleton-associated protein involved in neuronal development
Advisor: Li-Huei Tsai

Balazs, Alejandro - BBS
Purification and Characterization of Hematopoietic Stem Cells by Microarray Analysis
Advisor: Richard Mulligan

Balsara, Zarine - IMM
The interaction of Chlamydia trachomatis with mammalian host cells
Advisor: Michael Starnbach

Becker, Esther - BBS
Signaling Mechanisms Regulating Neuronal Apoptosis
Advisor: Azad Bonni

Bellovin, David - BBS
Impact of Epithelial-Mesenchymal Transition on the Regulation of Cell Motility and Colon Cancer Progression
Advisor: Arthur Mercurio

Bernstein-Hanley, Isaac - BBS
Genetic analysis of susceptibility to Chlamydia trachomatis in mouse
Advisor: William Dietrich

Billingsley, James - IMM
FceRI ubiquitylation negatively regulates receptor tyrosine phosphorylation and mast cell effector function
Advisor: Jean-Pierre Kinet

Bloodgood, Brenda - NSCI
Biochemical Compartmentalization and Synaptic Signaling in Spines
Advisor: Bernardo Sabatini

Bonasio, Roberto - IMM
MIGRATION AND FUNCTION OF CIRCULATING DENDRITIC CELLS
Advisor: Ulrich von Andrian

Borde, Madhuri - IMM
Novel roles for NFAT in T and B cell tolerance
Advisor: Anjana Rao

Boyden, Eric - BBS
Identification and characterization of a novel gene that controls mouse macrophage susceptibility to anthrax lethal toxin
Advisor: William Dietrich

Catic, Andre - IMM
Dynamic Evolution of Ubiquitin and of Ubiquitin-like Proteases
Advisor: Hidde Ploegh

Choi, Yoojin - NSCI
Mitogenic Niches in the Developing Cerebellum
Advisor: Rosalind Segal

Dandapani, Savita - BBS
Role of a-actinin-4 in the kidney
Advisor: Martin Pollak

de Vries, Saskia - NSCI
Modulation of Retinal Responses by Single Amacrine Cells
Advisor: Markus Meister

Dekker, John - NSCI
Molecular Analysis of Gating in Voltage-Dependent Ion Channels
Advisor: Gary Yellen

Dickman, Dion - BBS
A Genetic Screen for Mutants in Synaptic Transmission and an Analysis of Endocytosis at the Synapse
Advisor: Thomas Schwarz

Dietz, Shelby - NSCI
Plasticity and Development of the Mitral-Granule Reciprocal Synapse in the Mammalian Olfactory Bulb
Advisor: Venkatesh Murthy

Dimitri, Christopher - BBS
Analysis of the Ras-MAPK Pathway: Spatially Separate Docking Sites on ERK2 Regulate Distinct Signaling Events and Biological Processes
Advisor: John Blenis

Edson, Eleanore - NSCI
Contributions of Glutamate Transporters and Metabotropic Glutamate Receptors to Synaptic Transmission Over Development at the Retinogeniculate Synapse
Advisor: Chinfei Chen

Elias, Joshua - BBS
Proteome analysis by tandem mass spectrometry: Improvements and biological applications
Advisor: Steven Gygi

Everley, Patrick - BBS
The development of quantitative and functional proteomic technologies and their application to the study of prostate cancer
Advisor: Bruce Zetter

Fantana, Antoniu - NSCI
Odor Processing in the Olfactory Bulb: Structure of Mitral Cell Receptive Fields
Advisor: Markus Meister

Farago, Anna - BBS
Uncovering molecular and spatial predictors of brainstem neuron identity
Advisor: Susan Dymecki

Fredenburg, Ross - BBS
An Evaluation of the Molecular Model of alpha-Synuclein-mediated Cytotoxicity
Advisor: Peter Lansbury

Galloway, Jenna - BBS
Hematopoietic stem cell formation and differentiation in zebrafish
Advisor: Leonard Zon

Glater, Elizabeth - NSCI
The Mechanism for Axonal Transport of Mitochondria in Drosophila
Advisor: Thomas Schwarz

Goddard, Carson - NSCI
MHC Class I and the Homeostatic Regulation of CNS Synapses
Advisor: Carla Shatz

Goehring, Nathan - BBS
Assembly of the Bacterial Divisome
Advisor: Jonathan Beckwith

Goldman, Seth - BBS
The role of the shf operon in the biology of Shigella flexneri
Advisor: Marcia Goldberg

Gomila, Raúl - VIR
Identification and Characterization of Host Factors that Bind the Conserved 3' Terminal Stem Loop RNA of Flaviviruses
Advisor: Lee Gehrke

Goodman, Andrew - BBS
Regulation of acute and chronic virulence phenotypes in Pseudomonas aeruginosa
Advisor: Stephen Lory

Gooley, Joshua - NSCI
Entrainment of the Circadian Timing System by Light and Food
Advisor: Clifford Saper

Greenland, John - VIR
Vaccine antigen expression and immune responses
Advisor: Norman Letvin

Griffin, Robert - NSCI
Gene Expression Associated with Neuropathic Pain
Advisor: Clifford Woolf

Hafler, Brian - NSCI
Transcriptional Regulation of Olig2 in Motor Neuron Development
Advisor: David Rowitch

Hanna, John - BBS
Functional Analysis of Ubp6, a Proteasome-Associated Deubiquitinating Enzyme
Advisor: Daniel Finley

Hartman, Kenichi - NSCI
Regulation of Neuronal Morphology and Synaptic Development by Activity
Advisor: Venkatesh Murthy

Holz, Marina - BBS
Identification of Novel Binding Partners and Substrates of S6 Kinase 1 (S6K1)
Advisor: John Blenis

Horwitz, Andrew - BBS
Regulation of RNA Polymerase II by BRCA1, the breast cancer tumor suppressor
Advisor: Jeffrey Parvin

Huber, Damon - BBS
A Genetic Analysis of Protein Folding and Protein Translocation in Escherichia coli
Advisor: Jonathan Beckwith

Hughes, Christina - VIR
Menin is a Component of SET1-Like Histone Methyltransferase Complexes that Regulate Gene Expression
Advisor: Matthew Meyerson

Jackson, Alexander - NSCI
Subthreshold Currents Underlying the Spontaneous Firing of Hypothalamic Pacemaker Neurons
Advisor: Bruce Bean

Jagani, Zainab - BBS
The Regulation of the FOXO3a Transcription Factor in BCR-ABL-mediated Leukemogenesis
Advisor: Roya Khosravi-Far

Jung, David - BBS
Cis-acting elements controlling antigen receptor gene assembly
Advisor: Frederick Alt

Kelley-Clarke, Brenna - VIR
Characterization and functional assessment of the Kaposi's sarcoma herpesvirus latency-associated nuclear antigen C-terminal chromosome binding domain
Advisor: Ken Kaye

Kelly-Quintos, Casie - BBS
The contribution of epitope specificity in the human antibody response to the widely expressed bacterial surface polysaccharide PNAG
Advisor: Gerald Pier

Khurana, Vikram - NSCI
Mitogenic signaling and cell-cycle activation mediate neurodegeneration in Drosophila
Advisor: Mel Feany

Kollipara, Ramya - BBS
Genetic Analysis of the FoxO Transcription Factors in the Mouse
Advisor: Ronald DePinho

Koprivica, Vuk - NSCI
Mechanisms of Myelin Regeneration Inhibition
Advisor: Zhigang He

Kowalski, Jennifer - BBS
Regulation of Normal and Malignant Cellular Processes by the Cytoskeletal Scaffold, Cortactin
Advisor: Sheila Thomas

Lee, Jeff - BBS
Novel Activating EGFR Mutations in Human Cancers
Advisor: Matthew Meyerson

Lehtinen, Maria - NSCI
Survival and Death Signaling Pathways: From Single Cells to Organisms
Advisor: Azad Bonni

Liddle, Forrester - BBS
Mechanisms of STAT1 Activation and its Role in Colon Cancer
Advisor: David Frank

Lim, Jackie - BBS
Identifying and Characterizing a Mutation in Sec15l1, the Cause of Iron Deficiency Anemia in Hemoglobin Deficit (hbd) Mice
Advisor: Nancy Andrews

Liu, Chih Long - BBS
Dynamic high-resolution mapping of histone tail modifications in S. cerevisiae
Advisor: Stuart Schreiber

Love, Victoria - IMM
Cytotoxic T Lymphocyte Antigen-4 regulates cytotoxic T cells that cause myocarditis
Advisor: Andrew Lichtman

Lugo-Villarino, Geanncarlo - IMM
The Function of the Transcription Factor T-bet in Dendritic Cells
Advisor: Laurie Glimcher

Luo, Ji - BBS
Role of The Class IA Phosphoinositide 3-Kinase Regulatory Subunit p85 in Metabolism, Development and Cancer
Advisor: Lewis Cantley

Marcus, Jacob - NSCI
Orexin Receptors and the Central Autonomic System
Advisor: Joel Elmquist

McKellar, Claire - NSCI
A Program of New Gene Expression Induced by Synaptogenesis
Advisor: Carla Shatz

Medvedik, Oliver - BBS
Mechanisms of replicative lifespan extension during caloric restriction in Saacharomyces cerevisiae
Advisor: David Sinclair

Melroe, Gregory - VIR
Herpes Simplex Virus Inhibition of Innate Type-I Interferon Induction
Advisor: David Knipe

Moerke, Nathan John - BBS
Structural and Chemical Genetic Studies of Eukaryotic Translation Initiation Factors
Advisor: Gerhard Wagner

Molyneaux, Bradley - NSCI
Molecular Development of Corticospinal Motor Neurons
Advisor: Jeffrey Macklis

Murphey, Ryan - BBS
Chemical genetics and cancer models in zebrafish
Advisor: Leonard Zon

Myers, Kimberly - VIR
Membrane Perforation and Related Structural Transitions by Reovirus Particles
Advisor: Max Nibert

Nam, Yunsun - BBS
Structure and Function of Notch Transcription Complexes
Advisor: Stephen Blacklow

Ohgami, Robert - BBS
Identification and characterization of the Steap family of metalloreductases
Advisor: Mark Fleming

Osterfield, Miriam - BBS
Identification and characterization of binding partners for a cell surface receptor in chick brain development
Advisor: John Flanagan

Patten, Brooke - NSCI
Molecular Mechanisms of Radial Glia Formation in the Developing Cerebellum
Advisor: Gabriel Corfas

Paz, Carlos - BBS
Circadian Clock Function in the Mammalian Retina
Advisor: Charles Weitz

Peng, Wei - IMM
A Mutagenesis Approach to Study the Molecules Involved in CD1 Antigen Presentation
Advisor: Michael Brenner

Pfaff, Kathleen - BBS
Genetic analysis of the cell cycle and cancer in zebrafish
Advisor: Leonard Zon

Reiniger, Nina - BBS
Initiation of innate immunity to Pseudomonas aeruginosa lung infection: impact of wild type and mutant CFTR
Advisor: Gerald Pier

Rhee, James - BBS
Partnership of HNF4a with the transcriptional coactivator PGC-1a in the regulation of hepatic glucose and lipid homeostasis
Advisor: Bruce Spiegelman

Samuels, Benjamin - NSCI
Physiological Functions of Cdk5 in the Nervous System
Advisor: Li-Huei Tsai

Sánchez Irizarry, Cheryll - BBS
Functional and Biochemical Characterization of the Negative Regulatory Region of Mammalian Notch
Advisor: Stephen Blacklow

Sauer, Noel - BBS
Shigella Activation of the Actin Assembly Switch Protein N-WASP
Advisor: Marcia Goldberg

Schwartz, Daniel - BBS
Computational Algorithms for Spectral Prediction and Motif Discovery in Proteomic Sequence Data
Advisor: Steven Gygi

Simons, Amanda - BBS
Biochemical Functions of BRCA1 Protein Complexes
Advisor: Jeffrey Parvin

Skaar, Jeffrey - VIR
Biochemical and Genetic Characterization of Cullin 7- and PARC-containing Complexes
Advisor: James DeCaprio

Solimini, Nicole - BBS
Regulation of Mammary Epithelial Cell Survival and Acinar Morphogenesis by Proliferation Arrest
Advisor: Joan Brugge

Steffen, Leta - BBS
Zebrafish as a Model of Muscular Dystrophies and Insights into Titin's Role in Sarcomerogenesis
Advisor: Louis Kunkel

Stremlau, Matthew - BBS
TRIM5alpha: An Intracellular Defense Against Retroviruses
Advisor: Joseph Sodroski

Sun, Bryan - BBS
Mechanisms of Tsix-mediated repression of Xist
Advisor: Jeannie Lee

Taniguchi, Cullen - BBS
The Dissection of Insulin Signaling Isoforms In Vivo: Molecular Mechanisms of Hepatic Insulin Action
Advisor: C. Ronald Kahn

Ulm, Jacob Wesley - BBS
Elucidation of retroviral capsid residues involved in modulation of murine and human cell post-entry restriction
Advisor: Richard Mulligan

Venanzi, Emily - IMM
Mechanisms of aire control of immunological tolerance
Advisor: Diane Mathis

Vrabioiu, Alina - BBS
Structural and biochemical insights into yeast septin biology
Advisor: Timothy Mitchison

Walker, Sarah - BBS
Opposing Roles of STAT5 and STAT3 on Gene Regulation and Cancer
Advisor: David Frank

Wang, Jing - BBS
Exploring the mechanisms of axonal degeneration
Advisor: Zhigang He

Whitehead, Geoffrey - BBS
Genetic requirements for blastema formation and maintenance in zebrafish fin regeneration
Advisor: Mark Keating

Yiu, Glenn - NSCI
Signaling Mechanisms Limiting Axon Regeneration in the Adult Central Nervous System
Advisor: Zhigang He

2005

Aguirre, Andrew - BBS
Genetic Determinants of Pancreatic Ductal Adenocarcinoma
Advisor: Ronald DePinho

Alvarez, James - BBS
STAT3 signal transduction in human malignancy
Advisor: David Frank

Arnett, Kelly - IMM
Structural Studies of CD3, Signaling Molecules Associated With the T Cell Receptor
Advisor: Stephen Harrison

Auty, Roy - BBS
The purification and characterization of TFIID from Saccharomyces cerevisiae
Advisor: Stephen Buratowski

Barbera, Andrew - VIR
Role of the Latency Associated Nuclear Antigen N-terminus in Chromosome Association and Kaposi's Sarcoma-Associated Herpesvirus DNA Persistence
Advisor: Ken Kaye

Bassik, Michael - BBS
Regulation of ER Calcium Homeostasis and Apoptosis by Phosphorylation of BCL-2
Advisor: Stan Korsmeyer

Basu, Alo - NSCI
Characterization of an Amine-Modulated Stress Neuropeptide System in Homarus americanus
Advisor: Edward Kravitz

Bates, Emily Anne - BBS
Genetic analysis of neurodegeneration in Caenorhabditis elegans
Advisor: Anne Hart

Begun, Jakob - BBS
Investigating the host-pathogen interaction using a Staphylococcus-Caenorhabditis elegans model system
Advisor: Frederick Ausubel

Boyce, Michael - BBS
Chemical and cell biological approaches to study ER stress-induced apoptosis
Advisor: Junying Yuan

Bromley, Mary - BBS
Characterization of Cell Cycle and Morphology of an Avian Heart from Gastrulation through Looping and Chamber Outgrowth
Advisor: Clifford Tabin

Carothers, James - BBS
Experimental investigations of informational complexity and RNA functional activity
Advisor: Jack Szostak

Carthon, Brad - BBS
D-Type Cyclin Specificity in Murine Development
Advisor: Piotr Sicinski

Casolari, Jason - BBS
Coupling of Transcription and Nuclear Organization
Advisor: Pamela Silver

Chan, Amanda - VIR
The Role of Intramolecular Interactions in HHR23A Function in Ubiquitin-Mediated Protein Degradation
Advisor: Peter Howley

Cohen, Dena - BBS
Genetic and Molecular Analysis of X Chromosome Choice Elements at Tsix
Advisor: Jeannie Lee

Comander, Jason - BBS
Transcriptional and Functional Modulation of the Endothelial Cell Inflammatory Response by a Biomechanical Stimulus
Advisor: Michael Gimbrone

Custodio, Ángel - BBS
Analysis of Genetic Modifiers of Murine Iron Homesotasis
Advisor: Nancy Andrews

Dalkilic, Isin - BBS
Insights into the Role of FLNc in Muscle
Advisor: Louis Kunkel

Davis, Nicole - BBS
Molecular and Cellular Mechanisms of Left-Right Asymmetric Organ Morphogenesis
Advisor: Clifford Tabin

Devroe, Eric - BBS
Novel Interactions Between Human Cell Proteins and Human Immunodeficiency Virus Type 1
Advisor: Pamela Silver

Elia, Andrew - BBS
Proteomic Screen Reveals that the Polo-box Domain is a Phosphoserine/threonine-binding Module
Advisor: Lewis Cantley

Emerson, Mark - NSCI
A Misexpression Genetic Screen in Drosophila Identifies Candidate Axon Guidance Factors with Differential Expression
Advisor: David Van Vactor

Erwin, Phillip - BBS
Dynamic S-Nitrosylation of Endothelial Nitric Oxide Synthase in Vascular Endothelial Cells
Advisor: Thomas Michel

Farazi, Paraskevi - BBS
Modeling Liver Cancer in the Mouse
Advisor: Ronald DePinho

Frieden, Leslie - BBS
The role of a-actinin-2 in sarcomere development and function
Advisor: Alan Beggs

Gadea, Bedrick - BBS
Requirement of Aurora Kinases for M phase in Xenopus Egg Cycles
Advisor: Joan Ruderman

Gaudillière, Brice - BBS
Transcriptional Regulation of Neuronal Morphogenesis
Advisor: Azad Bonni

Gauguet, Jean-Marc - BBS
Normal and Malignant Lymphocyte Migration: Glycosyltransferases and Integrins in Lymphocyte Homing and CXCR4 Inhibition of Multiple Myeloma
Advisor: Ulrich von Andrian

Gregory, Brian - BBS
Molecular Interactions of E. coli s70 Region 4 Involved in Transcription Initiation
Advisor: Ann Hochschild

Harpavat, Sanjiv - NSCI
Roles of Thyroid Hormone in Chick Retinal Development
Advisor: Constance Cepko

Hayes, Gabriel - BBS
Control of developmental timing by microRNAs in C. elegans
Advisor: Gary Ruvkun

Hershey, Christine - BBS
The Role of the Microphthalmia Transcription Factor in Osteoclast Differentiation and Bone Development
Advisor: David Fisher

Hieronymus, Haley - BBS
Nuclear mRNA Export
Advisor: Pamela Silver

Hooper, Craig - BPH
Aspects of Helminth-associated T cell suppression: F4/80+ macrophage induction of T cell anergy via IL-6 and PD-L1
Advisor: Donald Harn, Jr

Huang, Julie - BBS
The role of ribosomal DNA silencing in the regulation of chromatin structure in Saccharomyces cerevisiae
Advisor: Danesh Moazed

Jackson, Shawn - VIR
Vaccine-Elicited Memory Cytotoxic T Lymphocytes
Advisor: Norman Letvin

Jadhav, Ashutosh - BBS
Regulation of vertebrate retinal development by the Notch signaling pathway
Advisor: Constance Cepko

James, Richard - BBS
Tissues and Molecules that Regulate Specification of the Avian Embryonic Kidney
Advisor: Thomas Schultheiss

Janse, Daniel - BBS
Pleiotropy in Saccharomyces cerevisiae and Small Molecule-Inducible Degradation of Proteins
Advisor: George Church

Jonsdottir, Gudrun - BBS
The Role of Myosin I in Actin Assembly and Endocytosis in Budding Yeast
Advisor: Rong Li

Kasper, Jocelyn - VIR
SV40 Large T Antigen Inactivates CUL7, a p53-Interacting Cullin
Advisor: James DeCaprio

Kau, Tweeny - BBS
Targeting the Nuclear Transport of a Forkhead Transcription Factor
Advisor: Pamela Silver

Kowalski, Michael - BBS
Cystic Fibrosis Transmembrane Conductance Regulator Signaling in Epithelial Cells in Response to Pseudomonas aeruginosa
Advisor: Gerald Pier

Kraves, Sebastián - NSCI
Molecular Analyses of the Circadian Control of Locomotor Activity in Mammals
Advisor: Charles Weitz

Landis, Mark - BBS
Function of Cyclin D1 in Development and Cancer
Advisor: Philip Hinds

Liang, Spencer - IMM
Elucidating the roles of PD-L1 and PD-L2 costimulation on T cell activation, differentiation and effector function
Advisor: Arlene Sharpe

Lilley, Brendan - BBS
Viral manipulation of endoplasmic reticulum protein degradation machinery
Advisor: Hidde Ploegh

Liu, Zhihua - BBS
The farnesylation of UCH-L1 enhances a-synuclein toxicity
Advisor: Peter Lansbury

Lu, Richard - VIR
Genetic Analyses of Human Immunodeficency Virus Type 1 Integrase Mutants
Advisor: Alan Engelman

Maimon, Gaby - NSCI
Cortex, Vision and Action
Advisor: John Assad

Manchanda, Nitasha - BBS
The role of the Neurofibromatosis 2 tumor suppressor merlin and the related ERM proteins in signaling to the actin cytoskeleton
Advisor: James Gusella

Mehta, Devangi - BPH
Regulation of Interleukin-21 expression and its biologic effects on B cells
Advisor: Michael Grusby

Meyers, Jennifer - IMM
Costimulation of effector T cells by Tim-4 and CD94/NKG2
Advisor: Vijay Kuchroo

Misaghi, Shahram - BBS
The Herpes virus US-region Gene Products and Glycoprotein turnover
Advisor: Hidde Ploegh

Moran III, Stewart - IMM
Molecular Mechanisms of Peripheral B Lymphocyte Development
Advisor: Shiv Pillai

Motyckova, Gabriela - BBS
Microphthalmia Transcription Factor Family Target Genes in Osteoclasts
Advisor: David Fisher

Munkittrick, Christin - BBS
The Roles of DNA Binding Specificity and ATPase Activity in Human Origin Recognition Complex Function
Advisor: Johannes Walter

Nissim, Sahar - BBS
Signaling Centers in Early Limb Development
Advisor: Clifford Tabin

Ou, Sharon - BBS
An Analysis of the Pairing Requirements for Transvection
Advisor: Chao-ting Wu

Pacholec, Michelle - BBS
Aminocoumarin Antibiotic Biosynthesis
Advisor: Christopher T Walsh

Paust, Silke - IMM
Molecular Target of regulatory T cells: Engagement of B7 on Effector T cells Inhibits Expansion and Autoimmune Disease
Advisor: Harvey Cantor

Pesola, Jean - BBS
Herpes Simplex Virus Gene Expression During Latency and Reactivation
Advisor: Don Coen

Petrillo, Jessica - VIR
Characterization of RNA and Protein Determinants of Alfalfa Mosaic Virus Replication
Advisor: Lee Gehrke

Petti, Allegra - BBS
Computational approaches to the inference of biological network connectivity
Advisor: George Church

Poulin- Porter, Danielle - VIR
The Carboxyl-Terminal Domain of Large T Antigen is Essential for the Simian Virus 40 Life Cycle
Advisor: James DeCaprio

Prather, Donald - BBS
Characterization of the transcription elongation factors Elf1 and TFIIS in S. cerevisiae
Advisor: Fred Winston

Protas, Meredith - BBS
The genetic basis of morphological evolution in Astyanax mexicanus, the Mexican cave tetra
Advisor: Clifford Tabin

Rana, Shalini - IMM
Alternative Splicing of FceRI b Subunit Pre-m RNA
Advisor: Jean-Pierre Kinet

Roberson, Christov - NSCI
G Protein Regulation of Inwardly Rectifying Potassium Channels
Advisor: David Clapham

Rutenberg, Joshua - BBS
Hairy-related transcription factors determine cardiac atrioventricular canal fate through Notch-dependent and -independent mechanisms
Advisor: Mark Mercola

Scherz, Paul - BBS
The Role of Descendants of Sonic Hedgehog-Expressing Cells in Limb Development
Advisor: Clifford Tabin

Scimone, Maria Lucila - IMM
From the bone marrow to the periphery: migratory pathways of T cells
Advisor: Ulrich von Andrian

Shalizi, Aryaman - BBS
MEF2 Functions in the Nervous System
Advisor: Azad Bonni

Shen, Jun - NSCI
Using Forward and Reverse Genetics to Study Genes That Control the Size of the Brain
Advisor: Christopher Walsh

Shendure, Jay - BBS
Multiplex Genome Sequencing and Analysis
Advisor: George Church

Starita, Lea - BBS
Substrates for the BRCA1/BARD1 ubiquitin ligase
Advisor: Jeffrey Parvin

Suscovich, Todd - VIR
Modulation of Tapasin Expression in Primary Effusion Lymphoma
Advisor: David Scadden

Takeda, David - BBS
Regulation of Mammalian Replication Initiators During the Cell Cycle
Advisor: Anindya Dutta

Tenney, Alan - BBS
Ligands for Receptor Tyrosine Phosphatases in Neural Development
Advisor: John Flanagan

Thomas, Seddon - VIR
The Role of Chemokine Receptors in CD1D-Restricted NK T Cell Trafficking
Advisor: Andrew Luster

Tran, Hien - NSCI
A Role for Forkheads in the Response to Stress
Advisor: Michael Greenberg

Wang, Duo - NSCI
Negative regulation of RNA interference in Caenorhabditis elegans
Advisor: Gary Ruvkun

Wang, Jing - BBS
Analysis of the Mixed Lineage Leukemia Protein in Transcriptional Regulation and Leukemogenesis
Advisor: Stan Korsmeyer

Whalen, Brian - NSCI
Early Events in Alzheimer's Disease: An Examination of Amyloid-Beta Protofibril Biology
Advisor: Dennis Selkoe

Williamson, Robin - BBS
Cytogenetic Approaches to Finding Auditory Genes
Advisor: Cynthia Morton

Winckler, Wendy - BBS
Human Genetic Variation in the Study of Recombination and Disease
Advisor: David Altshuler

Wingert, Rebecca - BBS
Genetic analysis of vertebrate hemoglobin synthesis: Characterization of the zebrafish hypochromic mutants chianti and shiraz
Advisor: Leonard Zon

Wong, Sharyl - VIR
Prediction and Characterization of Genetic Interactions
Advisor: Frederick Roth

Wood, Jason - BBS
Regulation of yeast and metazoan lifespan by sirtuins and the NAD+ salvage pathway
Advisor: David Sinclair

Wrobel, Carolyn - BBS
An Analysis of the Consequences of Colony-Stimulating Factor Receptor Hyperstimulation to Mammary Epithelial Cell Behavior and Morphogenesis
Advisor: Joan Brugge

Zakhary, Lisa - NSCI
Anatomical and Functional Analysis of MicroRNAs in Mammalian Olfactory Neurogenesis
Advisor: Catherine Dulac

Zhang, Lan - BBS
Functional Inference and Pattern Discovery from Integrated S. cerevisiae Networks
Advisor: Frederick Roth

Zhu, Zhou - BBS
Deciphering Gene Regulatory Networks via Integrative Genomic Approaches
Advisor: George Church

2004

Altevogt, Bruce - NSCI
Analysis of connexins in myelination
Advisor: David Paul

Appleton, Brent - VIR
The Three-Dimensional Structure and Functional Studies of the Human Cytomegalovirus DNA Polymerase Subunit, UL44
Advisor: James Hogle

Asher, Damon - IMM
Characterization of the Coxsackievirus and Adenovirus Receptor (CAR)
Advisor: Robert Finberg

Bianchetta, Michael - NSCI
Self-Association of the Muscle-Specific Receptor Tyrosine Kinase MuSK
Advisor: Jonathan Cohen

Bitterman, Kevin - BBS
Regulation of the Sir2 Family of Deacetylases
Advisor: David Sinclair

Blair, Nathaniel - NSCI
Contributions of Voltage-gated Sodium, Calcium and Potassium Currents to the Excitability of Nociceptive Sensory Neurons
Advisor: Bruce Bean

Borowski, Christine - IMM
Does the Pre-TCRa Chain Function as a Surrogate TCRa Chain?
Advisor: Harald von Boehmer

Brent, Ava - BBS
Developmental Regulation of Somitic Tendon Progenitors
Advisor: Clifford Tabin

Brittis, Perry - NSCI
RNA Based Mechanisms for Locally Regulating Axon Guidance Decisions
Advisor: John Flanagan

Brock, Amy - BBS
Control of Directional Extension of Lamellipodia by Extracellular Matrix and Mechanical Forces
Advisor: Donald Ingber

Chae, Teresa - NSCI
Genetic and Phenotypic Analysis of the hyh Mouse Mutant
Advisor: Christopher Walsh

Cho, Glen - BBS
In Vitro Selection to Create New Protein Libraries and Directed Evolution of New ATP-Binding Proteins from a Zinc Finger Scaffold Using mRNA-Display
Advisor: Jack Szostak

Chyung, Jay - NSCI
Cell Surface Events in the Amyloidogenic Processing of the Amyloid Precursor Protein
Advisor: Dennis Selkoe

Clatworthy, Anne - IMM
V(D)J Recombination and RAG-Mediated Transposition in Yeast
Advisor: Marjorie Oettinger

Cooper, Eric - IMM
Biochemical Analysis of the E6AP Ubiquitin Ligase and its Role in Angelman Syndrome
Advisor: Peter Howley

Currier, Sophie - NSCI
Genetics of Walker-Warburg Syndrome A Disorder of Brain, Muscle and Eye Development
Advisor: Christopher Walsh

Datta, Sandeep Robert - BBS
Coupling Growth Factors to the Apoptotic Machinery: Biochemical and Genetic Elucidation of the PI-3-Kinase/Akt/BAD Survival Signaling Cascade
Advisor: Michael Greenberg

Deuel, Thomas - NSCI
Doublecortin and the Doublecortin-like Kinase in CNS Development and Plasticity
Advisor: Christopher Walsh

Dodge, Matthew - BBS
The Localization and Action of an Intracellular MultiDrug Resistance Gene Product in Leishmania Parasites
Advisor: Dyann Wirth

Du, Jinyan - BBS
Identification and Characterization of MITF Target Genes in Melanocytes and Melanomas
Advisor: David Fisher

Elkin, Sheryl - BBS
The Role of the Carboxy Terminus of RAG2 in V(D)J Recombination
Advisor: Marjorie Oettinger

Fan, Melina - BBS
Regulation of the metabolic coactivator PGC-1a by p160 myb binding protein and by the anaphase promoting complex
Advisor: Bruce Spiegelman

Foster, Kelly - NSCI
Mechanisms and Functional Consequences of Short-Term Plasticity at Excitatory Synapses in the Cerebellum
Advisor: Wade Regehr

Fragoso, Ruben - IMM
Reconstitution of CD8 Single Positive T Cells Using a Chimeric CD8a-Lck Co-receptor Chain
Advisor: Steve Burakoff

Fukuto, Hana - BBS
Genetic Analysis of Chemosensation in C. elegans: the Role of G Protein-Coupled Receptor Kinase
Advisor: Anne Hart

Ge, Hui - BBS
Integrating Functional Genomic Information for Caenorhabditis elegans Early Embryonic Development
Advisor: Marc Vidal

Giraud, Jodel - BBS
Identification of Serine and Threonine Phosphorylation Sites in Insulin Receptor Substrate-1 and 2 that Regulate Insulin Signaling
Advisor: Morris White

Goodwin, Anne - BBS
Characterization of the Expression and Function of Wnt Signaling Components in Vascular Cells
Advisor: Patricia D'Amore

Grad, Yonatan - BBS
Computational Analysis and Prediction of Regulatory Sequences in Bilaterians
Advisor: George Church

Greka, Anna - NSCI
TRP Channels and the Cytoskeleton: Implications for Neuronal Growth and Cellular Motility
Advisor: David Clapham

Guogas, Laura - BBS
Structural and Biochemical Studies of RNA-Protein Interactions in Alfalfa Mosaic Virus
Advisor: Lee Gehrke

Gupta, Amitabh - BBS
Molecular and Cellular Mechanisms of the Cyclin-Dependent Kinase 5 (Cdk5) in Neocortical Migration and Layer Formation
Advisor: Li-Huei Tsai

Heerssen, Heather - NSCI
Mechanisms of Trk Receptor Retrograde Transport and Signaling
Advisor: Rosalind Segal

Heller, Elizabeth - BBS
Targeting Chromatin Remodeling through Ikaros
Advisor: Katia Georgopoulos

Hershberger, Karen - VIR
Diverse Killer-cell Ig-like Receptors (KIRs) of Rhesus and Sabaeus Monkeys: Evidence for Recombination Events in the Evolution of KIRs
Advisor: Norman Letvin

Hess, David - BBS
Genetic and molecular analysis of Spt10 and Spt21 of Saccharomyces cerevisiae: Roles in Histone Gene Transcription and other Chromatin-Related Processes
Advisor: Fred Winston

Ho, Hsin-Yi - BBS
Regulatory mechanisms of Cdc42-mediated actin assembly
Advisor: Marc Kirschner

Holm, Geoffrey - VIR
Mechanisms of Bystander T Cell Apoptosis in HIV-1 Infection
Advisor: Dana Gabuzda

Kao, Wynn - BBS
Degradation of E6AP in the Absence and Presence of HPV E6
Advisor: Peter Howley

Katz, Samuel - BBS
Regulation of Hematopoietic and Cardiac Development Mediated by the GATA Transcription Cofactor FOG-1
Advisor: Stuart Orkin

Kessler, Jeffrey - BBS
alpha-Synuclein Sequence Variants: Secondary Structure Formation and Aggregation
Advisor: Peter Lansbury

Kim, Sonia - BBS
Antizyme Inhibitor: A Novel Efector of Cell Growth and Proliferation
Advisor: Bruce Zetter

Kimberly, William - NSCI
Intramembrane Proteolysis and Signal Transduction: The g-Secretase Complex and its Connection to Alzheimer's Disease
Advisor: Dennis Selkoe

King, Ian - BBS
Transcriptional Repression by Polycomb-Group Proteins: in vitro Analysis and Correlation to in vivo Function
Advisor: Robert Kingston

Ko, Jane - NSCI
CDK5 in Neuronal Development and Potential Regulation of Kinesins
Advisor: Li-Huei Tsai

Kohli , Rahul - BBS
Macrocyclization Catalysis by Excised Thioesterase Domains from Natural Product Synthetases
Advisor: Christopher T Walsh

Konopka, Genevieve - NSCI
Regulation of STAT3 Signaling in Astrocyte Transformation
Advisor: Azad Bonni

Kwan, Kristen - BBS
Developmental and Cytoskeletal Control of Xenopus Cell Motility
Advisor: Marc Kirschner

Langenau, David - BBS
Transgenic Models of T-cell Acute Lymphoblastic Leukemia in the Zebrafish
Advisor: A. Thomas Look

Larschan, Erica - BBS
Coactivator function during Gal14-activation in S. cerevisiae
Advisor: Fred Winston

Leautaud, Veronica - BPH
Post-transcriptional regulation of mammalian heme oxygenase-1 mRNA: mechanistic studies of HO-1 mRNA stabilization in response to nitric oxide
Advisor: Bruce Demple

Lee, Dong - IMM
Cytokine Gene Regulation During T Helper Cell Differentiation
Advisor: Anjana Rao

Levine, Stuart - BBS
Purification and Characterization of Silencing Complexes in Humans
Advisor: Robert Kingston

Lieberman, Soyan - BBS
Regulation of Mos Kinase by CK2b
Advisor: Joan Ruderman

Lorenzo, Mayra - VIR
Downregulation of MHC Class I Molecules by Herpesviruses: Usurpation of Intracellular Trafficking Pathways
Advisor: Hidde Ploegh

Majewski, Michael - BBS
Molecular Characterization and Dynamic Properties of the PSD-95/d-catenin Interaction
Advisor: Kenneth Kosik

Martin, Colin - IMM
Tracing lymphopoiesis and thymic immigration with a pT_-controlled reporter gene
Advisor: Harald von Boehmer

Mehle, Andrew - VIR
HIV-1 VIF: A Novel SOCS-Box Protein that Targets APOBEC3G for Proteasomal Degradation
Advisor: Dana Gabuzda

Miller, Arlo - BBS
The Regulation of Melanoma Antigens by the Microphthalmia Transcription Factor
Advisor: David Fisher

Mills-Shaw, Kenna - BBS
Bim and TRAIL control two distinct death processes that mediate lumen formation during mammary morphogenesis
Advisor: Joan Brugge

Miyamoto, David - BBS
Probing the Functions of Kinesins in Mitosis
Advisor: Timothy Mitchison

Morshead, Katrina - IMM
Regulating V(D)J Recombination: Linking Chromatin Structure and Accessibility
Advisor: Marjorie Oettinger

Owens, Christopher - BBS
Viral Determinants of Post-Entry Restrictions on HIV-1/SIV Replication in Monkey Cells
Advisor: Joseph Sodroski

Peyerl, Friedrich - VIR
Structural Constraints on Primate Immunodeficiencey Virus Escape from Cytotoxic T Lymphocytes
Advisor: Norman Letvin

Roehrl, Michael - BBS
Structural and Chemical Genetic Insights into Protein-Protein Interactions of Phosphate-Dependent Cell Signaling: The Cases of Calcineurin and Protein Kinase C lota
Advisor: Gerhard Wagner

Sabatos-Peyton, Catherine - IMM
Tim-3 Regulation of the T Helper 1 (Th1) Immune Response
Advisor: Vijay Kuchroo

Sandoval, Gisela - NSCI
Molecular Genetic Analysis of an Interaction between the Vesicular Acetylcholine Transporter and Synaptobrevin in Caenorhabditis Elegans
Advisor: Gary Ruvkun

Sauvageot, Claire - NSCI
Genomic Analysis of Fate Choice in Cortical Progenitor Cells
Advisor: Charles Stiles

Seton-Rogers, Sarah - BBS
Cooperation of ErbB2 and TGF-beta in Mammary Epithelial Cell Migration and Invasion
Advisor: Joan Brugge

Shepard, Jennifer - BBS
Genetic Control of Cell Proliferation and Cancer Susceptibility in Zebrafish
Advisor: Leonard Zon

Smith, Jason - VIR
Thiol-dependent Activation of Alpharetrovirus Infection
Advisor: Jim Cunningham

Srinivasan, Dayalan - BBS
Identification and Characterization of Regulators of Mitotic Division and Spindle Position in Caenorhabditis elegans
Advisor: Sander van den Heuvel

St. Pierre, Susan - NSCI
Neuronal specification in Drosophila: the roles of rotund and squeeze, two related zinc finger genes
Advisor: Stefan Thor

Stanford, Jennifer - BBS
Regulation of Cdc25 and Wee1 in Xenopus Egg Cell Cycles
Advisor: Joan Ruderman

Steele, Lisa - IMM
Processing and Presentation of a Chlamydia trachomatis Antigen to CD8+ T Cells
Advisor: Michael Starnbach

Stolt, Peggy - BBS
The Structure and Function of the Phosphotyrosine Binding Domain of the Disabled-1 Adaptor Protein
Advisor: Stephen Blacklow

Su, Michael - IMM
Characterization of Signaling Pathways Induced by Agonist and Altered Peptide Ligands in the Fratricide of CD8+ Cytotoxic T Lymphocytes
Advisor: Steve Burakoff

Sullivan, Brandon - IMM
T-bet Regulation of Effector T Cell Differentiation
Advisor: Laurie Glimcher

Sun, Edna - BBS
Ephrin-B reverse signaling and cellular guidance
Advisor: John Flanagan

Tsai, Judy - BPH
The Role of GATA Transcription Factors in Adipogenesis
Advisor: Gokhan Hotamisligil

Tseng, Claire - BBS
Diversity-Generating Mechanisms of Non-Ribosomal Peptide Synthetases: I. Enzymes in the Biosynthesis of 3,5-Dihydroxy-L-phenylglycine II. Thioesterase Domain of the Surfactin Synthetase
Advisor: Christopher T Walsh

Van Dellen, Katrina - BPH
Novel Chitin-Binding Lectins and Chitin Synthases Involved in Entamoeba Cyst Wall Formation
Advisor:

Volles, Michael - BBS
The Aggregation and Membrane Permeabilizing Activity of alpha-Synuclein
Advisor: Peter Lansbury

Weaver, Valerie - BBS
Molecular Analyses of the Interactions Between Pseudomonas aeruginosa and Burkholderia spp.
Advisor: Roberto Kolter

Webster, Sarah - NSCI
Structures and mechanisms of gating in Shaker voltage-dependent potassium channels
Advisor: Gary Yellen

Willmann, Matthew - BBS
Calcium Sensor Kinases in Arabidopsis Innate Immunity: A Functional Genomics Approach
Advisor: Jen Sheen

Woo, Michele - BBS
Ribosomal S6 Kinase (RSK) Phosphorylates Filamin A on an Important Regulatory Site: Implications for RSK in the Control of Cell Migration
Advisor: John Blenis

Woolsey, Aaron - BBS
Characterization of a Novel Mechanism for Trypanosoma cruzi Invasion of Non-Phagocytic Mammalian Cells
Advisor: Barbara Burleigh

Wu, Pei-Yun Jenny - BBS
Functional and Structural Analysis of the S. cerevisiae SAGA Coactivator Complex
Advisor: Fred Winston

Yang, Fu-Chia - NSCI
The Potential Role for the EGF Receptor System in the Circadian Regulation of Locomotor Activity
Advisor: Charles Weitz

Yarrow, Justin - BBS
The Use and Discovery of Small Molecules that Affect the Actin Cytoskeleton
Advisor: Timothy Mitchison

Young-Pearce, Tracy - BBS
Taurine and Ligand Ion Channels in Photoreceptor Development
Advisor: Constance Cepko

2003

Baur, Scott - BBS
Developmental Genetics of the Distal Limb Skeleton
Advisor: Susan Dymecki

Carter, Alexandre - NSCI
Neurotrophin Modulation of Cerebellar Development and Synaptic Plasticity
Advisor: Rosalind Segal

Catapano, Lisa - NSCI
Stage-Specific Control over Neocortical Callosal Projection Neuron Survival and Differentiation
Advisor: Jeffrey Macklis

Cayabyab, Mark - BPH
The Role of HIV-1 Envelope Glycoproteins in the Pathogenesis of HIV/AIDS: A Study in a Nonhuman Primate Model
Advisor: Joseph Sodroski

Chackerian, Alissa - IMM
Susceptibility and Resistance to Mycobacterium tuberculosis: Lessons from the Mouse
Advisor: Samuel Behar

Chang, Dennis - NSCI
Circadian Clock Molecules of a Lepidopteran Insect, Antheraea pernyi, and Comparisons with the Fruit Fly, Drosophila melanogaster
Advisor: Steven Reppert

Chang, Tammy - IMM
The Role of B7 Costimulation in the Development of Experimental Autoimmune Encephalomyelitis
Advisor: Arlene Sharpe

Chen, Wen - BBS
Activation and Repression of Activity-Dependent Expression of Brain-Derived Neurotrophic Factor (BDNF)
Advisor: Michael Greenberg

Chou, Thomas - NSCI
Regulation of Sleep-Wake Timing: Circadian Rhythms and Bistability of Sleep-Wake States
Advisor: Clifford Saper

Claypool, Steven - IMM
Development and Characterization of an In Vitro Model to Study the Cell Biology of the Human Neonatal Fc Receptor, FcRn, in Polarized Epithelial Cells
Advisor: Richard Blumberg

Cowley, Glenn - BBS
A Molecular and Genetic Analysis of Neurofibromatosis Type 1
Advisor: James Gusella

Day, Cheryl - VIR
CD4+ T-Helper Cell Responses in Hepatitis C Virus Infection
Advisor: Bruce Walker

Dodge-Scully, Ingrid - IMM
Modulating the Immune Response: The Role of CD103 Expression and Tissue Origin in Dendritic Cell Function
Advisor: Hamid Band

Dudley, Darryll - IMM
Studies of the Mechanisms Directing Recombination in B and T Lymphocytes
Advisor: Frederick Alt

Fisher, Tracey - BBS
In Vitro Characterization of p90 Ribosomal S6 Kinase Domains and In Vivo Analysis of Insulin Receptor Substrate-2 Hepatic Function
Advisor: Morris White

Fisk, Ridgely - BBS
Identification and Characterization of Proteins Interacting with the C. elegans Spindle Component LIN-5
Advisor: Sander van den Heuvel

Fujikawa, Shelly - BBS
Possible Role of Membrane Compartments in the Origin of Life
Advisor: Jack Szostak

Gewurz, Benjamin - IMM
Viral Immune Evasion: A Structural Approach
Advisor: Hidde Ploegh

Griffin, Edmund - NSCI
Light, Cryptochrome, and Circadian Clocks
Advisor: Charles Weitz

Hansen, Michael - BBS
Ephrins as Positional Mapping Cues and Their Topographically Specific Effects on Retinal Axon Growth
Advisor: John Flanagan

Haslett, Judith - BBS
Molecular Pathology of Muscle Disease
Advisor: Louis Kunkel

Hickman, Mark - BPH
Apoptosis Induced by DNA Damage: Regulation of the Response to Specific Alkylated Bases
Advisor:

Hitchcock- Camp, Amy - BBS
Regulation of Ubiquitinated Membrane Proteins
Advisor: Pamela Silver

Hongay, Cintia - BBS
Mot3 is a Transcriptional Repressor of Ergosterol Biosynthetic Genes in Saccharomyces cerevisiae
Advisor: Fred Winston

Howland, Kimberly - IMM
Function of CD28 Costimulation in T Lymphocyte Activation
Advisor: Abul Abbas

Kaplan, Craig - BBS
Spt6, a Conserved, Essential Regulator of Chromatin Structure and Transcription Elongation by RNA Polymerase II
Advisor: Fred Winston

Klucking, Sara - VIR
Cytopathic Avian Retroviruses and the Death Receptor TVB
Advisor: John Young

LaBonte, Jason - VIR
HIV-1 Single Round Vector Systems for the Expression of Envelope Glycoproteins in Primary Cells
Advisor: Joseph Sodroski

Landhuis, Esther - IMM
Identification and Characterization of Ikaros Gene Regulatory Elements
Advisor: Katia Georgopoulos

Larvie, Mykol - BBS
X-ray Crystallography and Electron Microscopy of Cell Surface Receptors I. CD46 II.Transferrin Receptor
Advisor: Stephen Harrison

Leader, Benjamin - BBS
Identification and Characterization of Formin-2, a Gene Required for Meiosis in the Oocyte
Advisor: Philip Leder

Lee, Michelle - BBS
Endogenous Activin-like Signals in the Early Xenopus Embryo: Regional Specification and Timing of Smad2 Phosphorylation
Advisor: Malcolm Whitman

Lei, Elissa - BBS
Messenger RNA Nuclear Export
Advisor: Pamela Silver

Li, Hanjun - BBS
Application and Development of Multi-Dimensional NMR Spectroscopic Techniques to Study Protein Structure in Solution
Advisor: Gerhard Wagner

Lin, Jeffrey - VIR
Epstein-Barr Virus Nuclear Antigen 3C (EBNA3C) Regulates Transcription through Viral and Cellular Factors
Advisor: Elliott Kieff

Littlepage, Laurie - BBS
Regulation of the Mitotic Kinase Aurora-A
Advisor: Joan Ruderman

Losey, Heather - BBS
Glycosyltransferases Involved in the Biosynthesis of Glycopeptide Antibiotics
Advisor: Christopher T Walsh

Luftig, Micah - VIR
Characterization of Epstein-Barr Virus Latent Membrane Protein 1 Mediated NFkB Activation
Advisor: Elliott Kieff

Makowski Hayes, Liza - BPH
The Role of Fatty Acid Binding Protein aP2 in Atherosclerosis and Macrophage Biology
Advisor: Gokhan Hotamisligil

Martinez Gakidis, Maria Angelica - BBS
Vav Guanine Nucleotide Exchange Factors are Required for Integrin-Dependent Functions of Leukocytes
Advisor: Joan Brugge

Moran, Magdalene - NSCI
TLF is a Functional Regulator or Transcription with Targets that are Distinct from the TATA-Box Binding Protein (TBP)
Advisor: David Clapham

Myrick, Alissa - BPH
Mapping and Characterization of the pfmdr1 5' Upstream Region, and Analysis of the Transcriptional Response to Chloroquine in Plasmodium falciparum.
Advisor: Dyann Wirth

Nadal-Vicens, Mireya - NSCI
Signaling Mechanisns that Govern the Switch from Neuronal to Astrocyte Differentiation in Neocortical Progenitors
Advisor: Michael Greenberg

Ned, Renée - BBS
Characterization of the in vivo Requirement for Transferrin Receptor (TfR) in Tissue Development and Immune Function
Advisor: Nancy Andrews

Nigh, Elizabeth - NSCI
The Control of Protein Expression During Adaptive Neuronal Responses
Advisor: Michael Greenberg

Olveczky, Bence - NSCI
Retinal Processing of Natural Motion
Advisor: Markus Meister

On, Marina - IMM
Mechanism of FceRIb Mediated Signal Amplification
Advisor: Jean-Pierre Kinet

Palmer, Rachel - BBS
Transcriptional Targets of the Wilms Tumor Suppressor WT1 and Its Tumor-Associated Variants
Advisor: Daniel Haber

Patel, Hiten - BBS
Biosynthesis of the Pseudomonas aeruginosa Siderophore Pyochelin: Peptide Synthesis and Tailoring
Advisor: Christopher T Walsh

Paulding, Charles - BBS
Representational Difference Analysis (RDA) of Human and Mouse Cancers, and the Identification of the Tre2 (USP6) Oncogene as a Hominoid-Specific Gene.
Advisor: Daniel Haber

Powelka, Aimee - BBS
Arf6 Regulates Endocytic Trafficking in Two Examples of Polarized Cells
Advisor: Victor Hsu

Randell, John - VIR
Processivity of the Herpes Simplex Virus DNA Polymerase: Role of High-Affinity DNA Binding by the Processivity Subunit
Advisor: Don Coen

Rodriguez, Carolyn - NSCI
Innovating Genetic Technology to Map the Origin of the Precerebellar System
Advisor: Susan Dymecki

Rooney, Sean - IMM
The Role of Artemis in V(D)J Recombination, Class Switch Recombination and Tumor Suppression
Advisor: Frederick Alt

Rowan, Sheldon - BBS
Regulation and function of the retinal homeoprotein Chx10
Advisor: Constance Cepko

Schierle, Clark - BBS
Protein Targeting in Escherichia coli
Advisor: Jonathan Beckwith

Selinger, Douglas - BBS
High-resolution Microarray Analysis of RNA Degradation in Escherichia coli
Advisor: George Church

Solymar, Deborah - IMM
Lineage Specificity of Gene Expression: An Analysis of IL-4 and IL-13 Cytokine Production in Mast Cells and Th2 Cells
Advisor: Anjana Rao

Stavropoulos, Nicholas - BBS
Gain-of-Function Manipulation and Expression Analysis of the Xist Antisense GeneTsix
Advisor: Jeannie Lee

Swilling, Nathan - BBS
Functional Analysis of the RBCK Proteins
Advisor: Philip Hinds

Taddese, Abraha - NSCI
Electrophysiology of Spontaneously Active Tuberomammillary Nucleus Neurons
Advisor: Bruce Bean

Tanny, Jason - BBS
The mechanism of NAD-dependent deacetylation and its role in gene silencing in Saccharomyces cerevisiae
Advisor: Danesh Moazed

Tavazoie, Sohail - NSCI
The Development of Neural Connections from Retina to Thalamus: Maturation and Plasticity of Receptive Fields
Advisor: R. Clay Reid

Trinidad, Jonathan - NSCI
The Localization and Function of Neuregulin and the ErbB Receptors at the Neuromuscular Junction
Advisor: Jonathan Cohen

Tseng, Ai-Sun - BBS
Regulators of Growth and Cell Proliferation in Drosophila melanogaster
Advisor: Iswar Hariharan

Wang, Kevin - NSCI
Signaling Mechanisms Underlying Inhibition of Axonal Regeneration by CNS Myelin
Advisor: Zhigang He

Wensel, David - VIR
A Virus-Virus Interaction Circumvents the Virus Receptor Requirement for Infection by Pathogenic Retroviruses
Advisor: Jim Cunningham

Wong, Donny - BPH
Coordination of Mammalian Base Excision Repair of DNA by AP endonuclease 1 and DNA Polymerase b
Advisor: Bruce Demple

Yu, Channing - BBS
Genetics and Genomics of GATA-1 Function in Hematopoiesis
Advisor: Stuart Orkin

Zhang, Ying - NSCI
Where is it? Deriving Stimulus Location from the Responses of Visual Neurons
Advisor: R. Clay Reid

2002

Aguirre, Vincent - BBS
Identification of Serine Phosphorylation Sites in IRS1 that Inhibit Insulin Action
Advisor: Morris White

Borodovsky, Anna - BBS
Development and Application of Novel Inhibitors of Deubiquitinating Enzymes.
Advisor: Hidde Ploegh

Bradley, Kenneth - BBS
The Use of Somatic Cell Genetics to Identify Cellular Factors Involved in Host-Pathogen Interactions
Advisor: John Young

Brown, Sherine - BPH
The APOA1-CIII-AIV Gene Cluster: Effects on Acute and Long-Term Lipoprotein Responses to High Saturated Fat Diets
Advisor:

Carter, Adam - NSCI
Synaptic Transmission at Cerebellar Stellate Cells
Advisor: Wade Regehr

Chang, Aaron - BBS
Genetic Dissection of the Zinc Finger Transcription Factor GATA-2 in Mouse Development
Advisor: Stuart Orkin

Cooper, Andrew - VIR
Epstein-Barr Virus Nuclear Antigen 3A (EBNA-3A) Can Inhibit c-myc Expression and Lymphoblastoid Cell Growth
Advisor: Elliott Kieff

Corey, Laura - BBS
Chromatin Remodeling in the Mammalian Heat Shock Response
Advisor: Robert Kingston

Cortes-Cros, Marta - IMM
Aiolos and Ikaros as Regulators of B and T Cell Development and Effector Function
Advisor: Katia Georgopoulos

Deans, Michael - NSCI
Connexin 36 Localization and Function within the Rod Pathways of the Mouse Retina
Advisor: David Paul

Desai, Bimal - IMM
MITOCHONDRIA-ASSOCIATED FRAP: COORDINATING tHE GROWTH-REGULATORY SIGNALS WITH MITOCHONDRIAL ACTIVITY
Advisor: Stuart Schreiber

Dhavan, Rani - BBS
The Function and Regulation of Cyclin-Dependent Kinase 5
Advisor: Li-Huei Tsai

Doling, Amy - BBS
The Role of Antigen Compartmentalization in the Priming of CD8+ T Cells
Advisor: Michael Starnbach

Evans, Sarah - BBS
Analysis of the Rad3 and Cds1 Fission Yeast Checkpoint Kinases
Advisor: Tamar Enoch

Frantsve, Julie - BBS
Characterization of the Transformation and Signal Transduction Properties of TEL/JAK2 Fusion Proteins Associated with Human Leukemias
Advisor: D. Gary Gilliland

Furman, Margo - IMM
Immune Evasion in the Endoplasmic Reticulum: Dissecting the Strategies of Human Cytomegalovirus
Advisor: Hidde Ploegh

Gaus, Stephanie - NSCI
Neuroanatomic Substrates for Circadian Control of Sleep
Advisor: Clifford Saper

Gonzalez-Razzetti, Sonia - BPH
Degradation of the Human Papillomavirus Type 16 E7 Oncoprotein and E7-mediated Degradation of the Retinoblastoma Tumor Suppressor
Advisor: Karl Münger

Huang, Chris - BPH
Bc1-2 Proteins in Human Lung Cancer: Molecular Heterogeneity and Prognostic Value
Advisor:

Judson, Nicholas - BBS
Identification and Characterization of Essential Genes in Vibrio cholerae
Advisor: John Mekalanos

Kim, Peter - BBS
Refolding and NMR Structures of CD4-Lck and CD8a-Lck Complexes: A Novel Zinc-Mediated Dimerization Motif
Advisor: Michael Eck

Koontz, Jason - BBS
Frequent Fusion of JAZF1 and JJAZ1 Genes in Endometrial Stromal Tumors
Advisor: Jeffrey Sklar

Kurtz, Josef - IMM
Mechanisms of CD4+ T Cell Tolerance in Mixed Allogeneic Bone Marrow Chimeras Prepared with CD40L Blockade
Advisor: Megan Sykes

LaBonte, Michelle - VIR
Characterization of the CD94/NKG2 Family of Molecules in the Rhesus Monkey
Advisor: Norman Letvin

Lee, Ming-Sum - BBS
The Role of Cyclin-Dependent Kinase 5 in Alzheimer's Disease Pathogenesis
Advisor: Li-Huei Tsai

Liao, Chienwei - BBS
Genetic Analysis of Hematopoiesis in Zebrafish: Hemangioblast, Stem Cell, and Erythroid Differentiation in the cloche, bloodless, and riesling Mutants
Advisor: Leonard Zon

Lin, Jerry - NSCI
I. Characterization of an NMDA Receptor- Associated Complex Centered around NR1 II. The Role of AMPA Receptor Trafficking in Synaptic Plasticity
Advisor: Morgan Sheng

Lin, Michael - BBS
EphA Regulation of Rho GTPases through the Exchange Factor Ephexin during Axon Guidance
Advisor: Michael Greenberg

McGill, Gael-Christophe - BBS
Regulatory Pathways in Melanoma Cell Apoptosis
Advisor: David Fisher

McNamee, Elizabeth - VIR
Regulation of HSV Gene Expression: Two Viral Functions Implicated in the Stimulation of Late Gene Transcription
Advisor: David Knipe

Miller, Deborah - BBS
Biosynthesis of the Plague Iron Chelator Yersiniabactin and Characterization of its NRPS/PKS/NRPS Hybrid System
Advisor: Christopher T Walsh

Moy, Terence - BBS
Assembly and Nuclear Export of Ribosomal Subunits in Saccharomyces cerevisiae
Advisor: Pamela Silver

Munasinghe, Anusha - BPH
Exploring the Malarial Transcriptome by the application of Serial Analysis of Gene Expression to Plasmodium falciparum
Advisor: Dyann Wirth

Murray, Rose - BPH
Role of SPI1 in Salmonella typhimurium Pathogenesis
Advisor: Cathy Lee

Nickels, Bryce - BBS
The Interactions of Transcription Regulators with the s70 Subunit of RNA Polymerase
Advisor: Ann Hochschild

O'Brien, Kristine - BBS
Insights into the Role of Sarcospan in the Dystrophin-Associated Protein Complex
Advisor: Louis Kunkel

Peters, Maureen - BBS
Patterning the Dorsal-Ventral Axis of the Vertebrate Retina
Advisor: Constance Cepko

Piscopo, Denise - BBS
Characterization and Functional Analysis of the Cyclin G1 Protein
Advisor: Philip Hinds

Posey Morley, Sharon Celeste - IMM
The Actin Cytoskeleton and the Actin-Binding Protein Gelsolin in T Cell Signal Transduction
Advisor:

Radosevich, Michael - IMM
New Insights on the Regulation of Major Histocompatibility Complex Class II Genes
Advisor:

Rao, Navin - IMM
The Role of Ubiquitination in Cbl-mediated Negative Regulation of the Src-family and Syk/ZAP-70 Tyrosine Kinases
Advisor:

Reppas, John - NSCI
Saccadic Eye Movements and Early Vision
Advisor: R. Clay Reid

Rohatgi, Rajat - BBS
Biochemical Dissection of a Signaling Pathway that Controls Actin Assembly
Advisor: Marc Kirschner

Sarraf, Pasha - BBS
A Role for the Nuclear Receptor PPARg in Cancer
Advisor: Bruce Spiegelman

Serluca, Fabrizio - BBS
Genetic Dissection of Kidney Development: Distinct Pathways for Glomerulus and Tubule
Advisor: Mark Fishman

Seth, Kim - NSCI
A Molecular Genetic Investigation of the Role of RE-1/REST in the Transcriptional Regulation of the Corticotropin-Releasing Hormone (CRH) Gene
Advisor: Joseph Majzoub

Shaywitz, Adam - BBS
Role of the Phosphorylation-Dependent CREB/CBP Interaction in Transcriptional Activation by CREB
Advisor: Michael Greenberg

Smith, Jodi - BBS
Abl: Mechanism of Activation by Nck
Advisor: Bruce Mayer

Smith, Kristen - BBS
Activation of the Abl Tyrosine Kinase by Oligomerization
Advisor: Rick Van Etten

Stein, Pascal - BBS
A Visual Screen to Identify Proteins Based on Subcellular Localization: Characterization of Nurim and MIR1
Advisor: Tom Rapoport

Syken-Tolliday, Nicola - BBS
Assembly and Function of a Cytokinetic Ring in Saccharomyces cerevisiae
Advisor: Rong Li

Takasu- Scheiffele, Mari - BBS
Regulation of Excitatory Synapse Development by EphB Receptors
Advisor: Michael Greenberg

Taylor, Travis - VIR
Intranuclear Localization of the Herpes Simplex Virus ICP8 Protein
Advisor: David Knipe

Tsao, Doris - NSCI
Stereopsis
Advisor: Margaret Livingstone

Vedantham, Vasanth - NSCI
Moving Parts of Voltage-Gated Sodium Channels
Advisor: Stephen Cannon

Woda, Juliana - BBS
Regulation of Neural Plate Border Formation by Distal-less Proteins
Advisor: Mark Mercola

Wohlschlegel, James - BBS
Regulated Assembly of Protein Complexes at Origins of Replication
Advisor: Anindya Dutta

Wong, Jenise - BBS
Indentification and Functional Analysis of EWS-WT1 Target Genes in Desmoplastic Small Round Cell Tumor
Advisor: Daniel Haber

Yang, Hong - BBS
Molecular Inquiries into the Functions of the Retinoblastoma Protein
Advisor: David Livingston

Yoon, Clifford - BBS
Transcriptional Regulation of Metabolism by PPARg and PPARg coactivator-1
Advisor: Bruce Spiegelman

2001

Aalfs, Jeffery - BBS
A Biochemical Comparison of the Human ATP-dependent Nucleosome Remodeling Proteins SNF2 Homolog, SNF2-Like, and Brahma-Related Gene 1
Advisor: Robert Kingston

Agarwal, Suneet - IMM
Regulation of Cytokine Gene Expression during T Cell Differentiation
Advisor: Anjana Rao

Alexander, Kamilah - BBS
The Role of the Retinoblastoma Protein in Senescent Cell Cycle Exit, Survival, and Morphological Alteration
Advisor: Philip Hinds

Atluri, Pradeep - NSCI
The Role of Presynaptic Calcium in Short-Term Synaptic Plasticity
Advisor: Wade Regehr

Awobuluyi, Marc - NSCI
Translational Control of N-Methyl-D-Aspartate Subunit 1 (NMDAR1) Expression
Advisor:

Ballif, Bryan - BBS
Molecular Mechanisms Regulating MEK-MAP Kinase Cell Survival: A Critical Role for RSK and PDK1
Advisor: John Blenis

Bateman, Jack - BBS
Genetic Analysis of the Guanine Nucleotide Exchange Factor Trio and the Receptor Tyrosine Phosphatase Dlar in Drosophila melanogaster
Advisor: David Van Vactor

Best, Jennifer - BBS
Identification and Characterization of a Novel SUMO-1 Protease, SuPr-1, that Regulates Transcription
Advisor: Leonard Zon

Borghesani, Paul - NSCI
Neuronal Migration in Development and Degeneration
Advisor: Rosalind Segal

Brockman, Mark - VIR
Mechanisms of the Humoral Immune Response to Herpes Simplex Virus Infection
Advisor: David Knipe

Brown, Solange - NSCI
Local Circuits in the Retina: Spatial Sensitivity, Contrast Adaptation and Direction Selectivity of Retinal Ganglion Cells
Advisor: Richard Masland

Chao, Steven - NSCI
GAP-43: Regulation and Function
Advisor: Larry Benowitz

Chen, Andy - BBS
The Role of Ox40-Ligand in Costimulation
Advisor: Arlene Sharpe

Chen, Clark - BBS
Replication Accessory Factors and Genome Stability
Advisor: Richard Kolodner

Chen, Joseph - BBS
The Role of an Essential Membrane Protein (FtsQ) in Escherichia coli Cell Division
Advisor: Jonathan Beckwith

Christie, Richard - NSCI
In vivo Imaging of Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
Advisor: Bradley Hyman

Chua, Katrin - NSCI
Remodeling of the Spliceosome for Catalysis of Exon Ligation
Advisor: Robin Reed

Conway, Bevil - NSCI
Mechanisms of Color and Motion in Monkey Visual Cortex
Advisor: Margaret Livingstone

Coston, Wanda - IMM
Compartmentalized CD8+ T Cell Repertoires of the Male Genital Tract in Chronic HIV Infection
Advisor:

Criss, Alison - BBS
Mechanisms of Salmonella typhimurium Invasion and Signaling in Polarized Epithelial Cells
Advisor: James Casanova

Emerson, Lyndal - BPH
Genetic and Transcriptional Profile Analysis in Saccharomyces cerevisiae Reveal Role for Quinoline-Ring Antimalarial Drugs in Iron Uptake
Advisor: Dyann Wirth

Estep, Preston - BBS
Genomic Approaches to Connecting the Transcriptional Regulatory Network of Saccharomyces cerevisiae Stress Responses
Advisor: George Church

Fitzgerald, Daniel - BBS
Mechanism of Polycomb Repression in Drosophila Melanogaster
Advisor: Welcome Bender

Furman, Craig - VIR
DEF-1: An ARF Gap that Localizes to Focal Adhesions and Regulates Cell Attachment and Motility
Advisor: Thomas Roberts

Garcia, Jesus - NSCI
Activation and Regulation of Mechanosensitive Ion Channels
Advisor: David Corey

Growney, Joseph - BBS
Genomic Analysis of the Mouse Legionella pneumophila Susceptibility Locus
Advisor: William Dietrich

Johnson Hamlet, Michelle - BBS
Genetic Analysis of the Nonreceptor Protein Tyrosine Phosphatase corkscrew throughout Drosophila Development
Advisor: Lizabeth Perkins

Kang, Shin Jung - NSCI
A Dual Role of Capase-11 under Pathological and Physiological Conditions
Advisor: Junying Yuan

Karpova, Alla - BBS
Fine-tuning the Cellular Antiviral Response through the Regulation of Interferon Regulatory Factor-3
Advisor: Peter Howley

Karuman, Philip - BBS
Functional Analysis of LKB1, the Tumor Suppressor Found in Peutz-Jegher's Syndrome
Advisor: Junying Yuan

Kaufmann, Nancy - BBS
Genetic Analysis of Dlar in Axon Guidance and Synaptic Development in Drosophila melanogaster
Advisor: David Van Vactor

Kleijnen, Mauritius - VIR
Ubiquitin-like hPLIC Proteins: A Link between Ubiquitination and Proteasomal Degradation
Advisor: Peter Howley

Kolchinsky, Peter - VIR
CD4-Independence of a CCR5-Using HIV-1 Primary Isolate
Advisor: Joseph Sodroski

Korey, Christopher - BBS
A Screen for New Motor Axon Guidance Mutants: The Genetic and Molecular Analysis of small bristles
Advisor: David Van Vactor

Kreitzer, Anatol - NSCI
Activity-Dependent Modulation of Synaptic Strength in the Central Nervous System
Advisor: Wade Regehr

Langdon, Robert - BBS
Transcriptional Activation by Natural and Artificial cAMP Receptor Proteins in Escherichia coli
Advisor: Ann Hochschild

Lechler, Terry - BBS
Generation and Polarization of the Yeast Actin Cytoskeleton
Advisor: Rong Li

Lee, Sung-Joon - BPH
ApoB Lipoproteins Containing Apoc3 and Recurrent Coronary Events in Diabetic Patients
Advisor:

Lin, Chin-Yo - BPH
Functional Analysis of the Conserved Carboxyl-terminal Domain of the Mitotic Polo-like Kinase Plk
Advisor: Raymond Erikson

Lostroh, Candi Phoebe - BBS
Activation of the invF and prgH Promoters by HilA, a Virulence Factor from S. enterica sv. Typhimurium
Advisor: Cathy Lee

Lucas- Orwant, Robin - BBS
Regulation of hilA Expression in Salmonella typhimurium
Advisor: Cathy Lee

Magavi, Sanjay - NSCI
Induction of Neurogenesis in the Neocortex of Adult Mice and Assessment of the Functional Integration of Adult-born Neurons
Advisor: Jeffrey Macklis

Mason, Heather - NSCI
Cellular and Molecular Mechanisms of Neuronal Chain Migration
Advisor: Gabriel Corfas

Million, Ryan - BBS
Study of Oncogenic Abl Translocations in a Murine Model of Leukemogenesis
Advisor: Rick Van Etten

Mittler, Ellis Stewart - VIR
Mechanisms and Pathways of Picornaviral Entry into HeLa Cells
Advisor: James Hogle

Monroe, Robert - BBS
Developmental Regulation of the RAG2 Gene and the T Cell Receptor Delta Locus
Advisor: Frederick Alt

Morehouse Ettinger, Heather - BBS
Analysis of Nucleocytoplasmic Transport Receptors
Advisor: Pamela Silver

Morrill, James - NSCI
Biophysical Properties of the Skeletal Muscle L-Type Calcium Channel in Health and Disease
Advisor: Stephen Cannon

Morrow, Eric - BBS
The Function of Crx and NeuroD Transcription Factors in the Development of the Neural Retina in Rodent
Advisor: Constance Cepko

Mundy, Cynthia - BBS
Initiation of V(D)J Recombination by the Recombination Activating Genes, RAG1 and RAG2
Advisor: Marjorie Oettinger

Ndung'u, Peter - BPH
Human Immunodeficiency Virus Type 1 Subtype C: Molecular Characterization and Development of an Animal Model
Advisor: Myron Essex

Orlando, Lianna - NSCI
Metabotropic Glutamate Receptors in Rat Striatum: Interactions with NMDA Receptors
Advisor:

Purcell, Patricia - BBS
Genes Involved in Early Development of the Mouse Cranial Sensory Placodes
Advisor: Richard Maas

Rengarajan, Jyothi - BPH
NFAT Transcription Factors in T Helper Cell Differentiation and Homeostasis
Advisor: Laurie Glimcher

Rolls, Melissa - BBS
Establishing Domains within the Continuous Endoplasmic Reticulum Membrane
Advisor: Tom Rapoport

Rones, Melissa - BBS
Patterning of the Heart and Kidney Fields by Notch Signaling
Advisor: Mark Mercola

Scharf, Jeremiah - NSCI
Comparative Genomic Analysis of the Spinal Muscular Atrophy (SMA) Region in Mouse and Man: Applications for Understanding Disease Pathogenesis
Advisor: Louis Kunkel

Schneider, Valerie - BBS
Head and Heart Induction in Xenopus laevis
Advisor: Mark Mercola

Schuyler, Scott - BBS
Ase1p is a Dynamic Microtubule Crossbridge Essential for Anaphase B
Advisor: David Pellman

Stevenson, Lauren - BBS
Identification and Analysis of S. cerevisiae Genes that Affect Cell Cycle when Overexpressed
Advisor: Ed Harlow

Sturm-Ramirez, Katharine - BPH
Biological Cofactors of HIV Transmission in Women
Advisor: Phyllis Kanki

Sullivan, Eileen Kelly - BBS
Transcriptional Control by Human Heat Shock Factor One
Advisor: Robert Kingston

Tian, Hongping - BBS
A Genetic Study of Membrane Protein Insertion and Disulfide Bond Formation in Escherichia coli K-12
Advisor: Jonathan Beckwith

Weiss, Valerie - BBS
The Function and Three-Dimensional Structure of the Oligomeric Yeast Arginine Methyltransferase, Hmt1
Advisor: James Hogle

Wilcox, Heather - IMM
Structure/Function Analysis of the Tyrosine Kinase Itk in Signal Transduction through the T Cell Antigen Receptor
Advisor: Leslie J. Berg

Yeo, Chang-Yeol - BBS
Mechanisms of TGFb Family Signaling During Early Vertebrate Embryogenesis
Advisor: Malcolm Whitman

Zinser, Erik - BBS
A Genetic Analysis of the Physiological Basis of Microbial Evolution during Prolonged Starvation
Advisor: Roberto Kolter

2000

Adams, Amy - BBS
Identification of the Hormone Contact Domains and Early Signaling Events of the Human Parathyroid Hormone 1 (hPTH1) Receptor
Advisor: Michael Rosenblatt

Adkins- Huet, Heather - VIR
Indentification and Characterization of TNFR-like Receptors for Subgroups B, D and E Avian Leukosis Viruses: Two Isoforms of a Common Receptor Explain Non-reciprocal Receptor Interference between Cytopathic and Non-cytopathic Avian Retroviruses
Advisor: John Young

Aghi, Manish - NSCI
Improving the Efficacy of Chemosensitizing Brain Tumor Gene Therapies
Advisor: Xandra Breakefield

Bagley, Jessamyn - IMM
T Cell Mediated Rejection of MHC class I Mismatched Skin Allografts
Advisor: John Iacomini

Baker, Gregory - BBS
Characterization of the Functional Domains of the D-Type Cyclins
Advisor: Philip Hinds

Beck, Laurence - BBS
Cell-Cell Interactions and Microenvironmental Influences in Vascular Development and Pathology
Advisor: Patricia D'Amore

Blackard, Jason - BPH
Genetic Variation of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat
Advisor: Myron Essex

Boerger, Adrienne - BBS
The Use of Retroviral Vectors Preloaded with a Retroviral Receptor-Ligand Bridge Protein for Cell-Type Specific Viral Targeting and as a System for Studying Avian Leukosis Virus Entry
Advisor: John Young

Brasher, Bradley - BBS
Mechanism of Regulation of the c-Abl Tyrosine Kinase: Mutagenic and Enzymological Studies
Advisor: Rick Van Etten

Chen, Hsiuchen - BBS
A Transgenic Approach to Studying Prostate Growth Regulation
Advisor: Philip Leder

Choi, Yun-Beom - NSCI
Molecular Analysis of Modulatory Sites on the NMDA Receptor: Redox, Zn2+, and Nitric Oxide-Related Species
Advisor: Stuart Lipton

Csejtey Olland, Andrea - VIR
Structure of the Reovirus Outer Capsid Protein Sigma 3
Advisor: Stephen Harrison

Das, Ananya - BBS
Evolutionary Analysis of in vitro Selected Ligase Ribozymes
Advisor: Jack Szostak

Davidson, John - BPH
The Involvement of Oxygen in Heat Toxicity in Saccharomyces cerevisiae
Advisor: Robert Schiestl

Day, Michelle - NSCI
The Effects of Serotonin 5-HT2A Agonists and Antagonists on High-Voltage-Activated Calcium Currents in Prefrontal Pyramidal Neurons
Advisor:

DeTulleo, Louis - VIR
Viral Usage of the Clathrin Endocytic Pathway
Advisor: Tomas Kirchhausen

Dittman, Jeremy - NSCI
Presynaptic Modulation of Transmitter Release in the Central Nervous System
Advisor: Wade Regehr

Donovan, Adriana - BBS
A Genetic Analysis of Vertbrate Iron Metabolism: Characterization of the Zebrafish Blood Mutants weissherbst and chardonnay
Advisor: Leonard Zon

Ehmann, David - BBS
Enzymology of Domains of Non-ribosomal Peptide Synthetases Involved in Lysine and Enterobactin Biosynthesis
Advisor: Christopher T Walsh

Field, Jessica - BPH
Evolutionary Origins of Entamoeba histolytica Inferred from Biochemical, Cellular, and Molecular Data
Advisor:

Fitzgerald, Marilyn - BBS
Regulation of Syndecan Ectodomain Shedding
Advisor: Merton Bernfield

Garcia, Claudia - BBS
Development of the Blood-Brain Barrier: Investigations of the Role of Astrocyte-Endothelial Cell Interactions Using an in Vitro Coculture Model
Advisor: Patricia D'Amore

Harper, Jay - BBS
Expression of VEGF and the VEGF Receptor Neurophilin-1 during Endochondral Ossification
Advisor: Michael Klagsbrun

Healy, Vicki - BBS
Investigation of the Mechanism and Specificity of D-Ala-D-Ala Ligases in Bacterial Cell Wall Biosynthesis and the VanA (D-Ala-D-Lac Ligase) and VanC2 (D-Ala-D-Ser Ligase) Variants that Underlie Vancomycin Resistance
Advisor: Christopher T Walsh

Heanue, Tiffany - BBS
Vertebrate Dachshund Genes Function in Evolutionarily Conserved Regulatory Cassettes to Control Developmental Fate
Advisor: Clifford Tabin

Hood, Jennifer - BBS
Studies of Nuclear Trafficking in Saccharomyces cerevisiae
Advisor: Pamela Silver

Horowitz, Lisa - NSCI
Connectivity in the Mouse Olfactory System
Advisor:

Huber, Tara - BBS
Studies of the Induction of Hematopoietic Mesoderm in Xenopus
Advisor: Leonard Zon

Jun, Helen (Toni) - VIR
Analysis of Cellular Signaling Pathways Activated by Polyomavirus Middle T Antigen
Advisor: Thomas Roberts

Kass, Jamie - BBS
Genetic Analysis of a Polymodal Sensory Neuron in C. elegans
Advisor: Joshua Kaplan

Kim, James - IMM
The In Vivo Function of the Transcription Factor c-maf
Advisor: Laurie Glimcher

Lin, Robert - BBS
The Roles of the T-box Transcription Factor Genes TBX3 and TBX5 in Limb and Cardiac Development
Advisor: Jonathan Seidman

Lippincott, John - BBS
Identification and Characterization of an Actomyosin Contractile Ring Involved in S. cerevisiae Cytokinesis
Advisor: Rong Li

Malick, Amy - NSCI
On Trigeminohypothalamic Pain Pathways and How they Contribute to Anorexic Behavior
Advisor: Rami Burstein

Martin, III, Glover - BBS
Regulation of Selenocysteine Insertion in Eukaryotes: Functional Parameters of the SECIS Element and in vivo Efficiency of Selenoprotein Synthesis
Advisor:

Murtaugh, Lewis - BBS
Molecular Mechanisms Regulating Cartilage Formation and Maturation
Advisor: Andrew Lassar

Nadeau, Philip - NSCI
An Investigation of the Role of Apolipoproteins, Lipoproteins and the Presenilin Proteins in Amyloid Beta Metabolism and Alzheimer's Disease
Advisor: Bruce Yankner

Naisbitt, Scott - NSCI
The Molecular Organization of the Postsynaptic Density by GKAP and Shank
Advisor: Morgan Sheng

Ng, Yin-Shan - BBS
Differential Roles of Vascular Endothelial Growth Factor (VEGF) Isoforms in Vascular Development
Advisor: Patricia D'Amore

Nolan, Katherine - BBS
Characterization of Rac Signaling Pathways in Drosophila melanogaster
Advisor: Jeffrey Settleman

Patrick, Gentry - BBS
Regulation of the p35/cdk5 Kinase in Neuronal Development and Neurodegenerative Disease
Advisor: Li-Huei Tsai

Pfleger, Cathie - BBS
Regulation and Substrate Specificity of the Anaphase Promoting Complex
Advisor: Marc Kirschner

Phillips, Dereth - BBS
Competitive Growth Analysis of E. coli In-Frame Deletion Mutants across a Spectrum of Environmental Conditions
Advisor: George Church

Pollard, Jack - BBS
Surveying Functional Nucleic Acid Sequence Space
Advisor: Jack Szostak

Porro, Elena - BBS
Characterization of cfap, a Novel cdk5 Associated Protein
Advisor: Li-Huei Tsai

Rehm, Heidi - BBS
Toward an Understanding of Norrie Disease and the Putative Growth Factor Norrin
Advisor: Cynthia Morton

Salic, Adrian - BBS
Biochemical and Developmental Studies of the Wnt Signaling Pathway
Advisor: Marc Kirschner

Schechter, Lisa - BBS
Indentification of Transcription Factors and DNA Elements that Control hilA Expression in Salmonella typhimurium
Advisor: Cathy Lee

Shannon, Katie - BBS
Regulation of Actomyosin Ring Assembly and Contraction in Budding Yeast
Advisor: Rong Li

Shen, Elisa - BBS
The Role of RNA-binding Proteins in mRNA Metabolism in Saccharomyces cerevisiae
Advisor: Pamela Silver

Silvey, Katherine - IMM
Reovirus Type 1 Lang: A Model to Study M Cell Specific Pathogen Interactions and Secretory IgA Function in the Intestine
Advisor:

Smith, Devyn - BBS
Patterning and Evolution of the Vertebrate Gut
Advisor: Clifford Tabin

Snitkovsky, Sophie - VIR
Targeting of Retroviral Vectors to Specific Cell Types Mediated by Soluble Retroviral Receptor-Ligand Bridge Proteins
Advisor: John Young

Syken, Josh - BBS
TID1 Encodes Two Mitochondrial Modulators of Apoptosis
Advisor: Karl Münger

Taraszka Hastings, Karen - IMM
Molecular Basis of Integrin aEb7 Recognition of E-cadherin
Advisor: Michael Brenner

Ware, Marcus - NSCI
Cellular and Molecular Events in the Development of the Cerebral Cortex
Advisor: Christopher Walsh

Wawersik, Stefan - BBS
A Role for the Growth Factor Bone Morphogenetic Protein 7 in Early Development of the Murine Eye
Advisor: Richard Maas

Weinstein, Edward - BBS
Involvement of the Heregulin/Neu Axis in Breast Cancer Growth and Development
Advisor: Philip Leder

Wills, Zachary - BBS
Signaling Components Regulating Motor Axon Guidance in the Fruitfly Drosophila melanogaster
Advisor: David Van Vactor

Winter, Dirk - BBS
Indentification and Characterization of the Budding Yeast Arp2/3 Complex
Advisor: Rong Li

Wong, Guang - IMM
Molecular Analysis of the Complexities and Functions of Mast Cell Proteases and Proteoglycans
Advisor: Richard Stevens

Xu, Haiyan - BPH
Spatial Regulation of TNFa Action in Adipocytes and Adipose Tissue
Advisor: Gokhan Hotamisligil

Yballe, Claudine - BBS
Roles of Phosphoinositide 3-Kinase (PI3K) p85 Regulatory Subunits in Development and Physiology
Advisor: Lewis Cantley

1999

Accola, Molly - IMM
Molecular Interactions in Primate Immunodeficiency Virus Assembly
Advisor: Heinrich Gottlinger

Allwardt, Brenda - NSCI
Ultrastructural Analysis of Photoreceptors in Wildtype and Mutant Zebrafish Larvae
Advisor: John Dowling

Anderson, Ana - IMM
T Cell Cross-reactivity in the Selection and Expansion of the Autoreactive T Cell Repertoire
Advisor: Vijay Kuchroo

Anderson, David - IMM
The B7:CD28/CTLA-4 Costimulatory Pathway in Human T cell Activation and Multiple Sclerosis
Advisor: David Hafler

Barnes-Weninger, Stacie - NSCI
Role of Corticotropin-Releasing Hormone (CRH) and CRH-Like Molecules in Stress-Induced Behavior
Advisor: Joseph Majzoub

Barrett, Peter - BBS
tkr-1, a C. elegans tachykinin receptor homolog
Advisor:

Beauregard- Garber, Kathryn - BBS
Interactions of Anthrax Toxin with Mammalian Cells
Advisor: R. John Collier

Behar, Vered - BBS
Insights into the Bimolecular Interactions in the Parathyroid Hormone--Receptor System
Advisor: Michael Rosenblatt

Brown, Julia - IMM
T Cell Priming and TH Subset Differentiation in B7-Deficient Mice: Immunization with TNP-KLH and Infection with Leishmania Major
Advisor: Arlene Sharpe

Brownlie, Alison - BBS
Characterization of the hypochromic blood mutants zinfandel, chianti and sauternes: A genetic analysis of hemoglobin synthesis in the zebrafish, Danio rerio.
Advisor: Leonard Zon

Chapman, Carolyn - BBS
Analysis of the Fission Yeast Cell Cycle Checkpoint Gene rad3+
Advisor: Tamar Enoch

Chou, Susanna - BBS
Mechanisms of Accessibility and Activation at Eukaryotic Promoters: the Role of TFIIA, TFIIB and Promoter Accessibility in Yeast
Advisor: Kevin Struhl

Das, Saumya - NSCI
Identification and Characterization of a Novel N-Methyl-D-Aspartate Receptor Subunit NR3A
Advisor: Nobuki Nakanishi

Dudley, Aimée - BBS
The SAGA Complex and Spt-dependent Promoter Function in Saccharomyces cerevisiae
Advisor: Fred Winston

Elliott, Jennifer - BBS
Assembly and Translocation of Anthrax Toxin
Advisor: R. John Collier

Fanning, Paul - BBS
Regulation of Endochondral Bone Growth in Mice by the Gene for Osteochondrodystrophy (ocd)
Advisor: Bjorn Olsen

Forbes, Kristi - BBS
Regulation of Cdc25p in the Fission Yeast DNA Replication Checkpoint
Advisor: Tamar Enoch

Fox, Jeremy - BBS
Identification of Genes Required for Neuronal Migration in the Developing Mammalian Cerebral Cortex
Advisor: Christopher Walsh

Garber, David - BBS
Phenotypic Analysis of Latency-Associated Transcript Mutants of Herpes Simplex Virus Type 1
Advisor: David Knipe

Garraway, Levi - BBS
Genetic Studies of Oxidant Resistance Determinants in the Leishmania Parasite
Advisor: Stephen Beverley

Gonzalez, Jorge Luis - NSCI
Cellular and Biochemical Analysis of Mutations That Affect Cerebral Cortical Development
Advisor: Christopher Walsh

Gozani, Or Pinchas - BBS
Functional Analysis of RNA-Protein and Protein-Protein Interactions during Spliceosomal Assembly
Advisor: Robin Reed

Green, Donnella - NSCI
Functional Consequences of Sodium Channel Mutations in Human Neuromuscular Disease and a Novel Mechanism for Acetazolamide Therapy
Advisor: Stephen Cannon

Irie, Yoko - IMM
Role of CD8b in T Cell Activation and Development
Advisor:

Juo, Peter - BBS
Characterization of Signaling Pathways Involved in Fas-Mediated Apoptosis
Advisor: John Blenis

Kahana, Jason - BBS
Mitotic Spindle Positioning and Microtubule Dynamics in Saccharomyces cerevisiae
Advisor: Pamela Silver

Kostrub, Corwin - BBS
Analysis of the Fission Yeast Cell Cycle Checkpoint Gene hus1+
Advisor: Tamar Enoch

Kwon, Young - BBS
The role of the p35/cdk5 kinase in cortical development
Advisor: Li-Huei Tsai

London, Cheryl - IMM
Immunologic Memory: Generation and Properties of Memory T Lymphocytes
Advisor: Abul Abbas

Lu, Yu - BBS
Cloning and Functional Characterization of Drosophila Pkn, a Rho/Rac Effector Target Kinase, Required for Embryogenesis
Advisor: Jeffrey Settleman

Ma, Le - BBS
Regulation of the Actin Cytoskeleton by Cell Signaling
Advisor: Marc Kirschner

Manilay, Jennifer - IMM
Environmental Determinants of Natural Killer Cell Recognition and LY-49 Receptor Expression in Mixed Allogeneic Bone Marrow Chimeras
Advisor: Megan Sykes

Marquis, John - BPH
Human Cell Response to Subtoxic Levels of Nitric Oxide
Advisor: Bruce Demple

Means, Robert - VIR
Factors Affecting the Antigenicity and Immunogenicity of SIVmac Envelope
Advisor: Ronald Desrosiers

Moore Rodriguez, Christine - BBS
Characterization of mRNA Capping Enzyme and its Recruitment to RNA Polymerase II
Advisor: Stephen Buratowski

Morris, James - BBS
A Genetic and Molecular Analysis of Transvection at the yellow Locus of Drosophila melanogaster
Advisor: Chao-ting Wu

Moynihan, Elizabeth - BBS
The Identification and Characterization of Fission Yeast Genes Required for Normal Cell Division When Ribonucleotide Reductase Is Inhibited
Advisor: Tamar Enoch

Nguyen-Huynh, Anh - BBS
The Roles of Origin-Flanking Sequences and Cellular Transcription Factors in Herpes Simplex Virus OriS-Dependent DNA Replication
Advisor: Priscilla Schaffer

Pagan Westphal, Sylvia - BBS
The Transfer of Left-Right Positional Information During Chick Embryogenesis and Situs-Specific Morphogenesis
Advisor: Clifford Tabin

Paradis, Suzanne - BBS
Molecular and Genetic Analysis of an Insulin Receptor-like Signaling Pathway in C. elegans
Advisor: Gary Ruvkun

Powell, Christina - VIR
Role of the Mammalian Transcription Factor LSF at the G1/S Transition of the Cell Cycle
Advisor: Ulla Hansen

Pratt, Megan - NSCI
Mapping Noncompetitive Antagonist Binding Sites in the Nicotinic Acetylcholine Receptor
Advisor: Jonathan Cohen

Provoda, Chester - BBS
Biogenesis of Synaptic Vesicles
Advisor: Kathleen Buckley

Refaeli, Yosef - IMM
Regulation of Apoptosis in CD4+T cells
Advisor: Abul Abbas

Reinhart, Brenda - BBS
The Regulation of Developmental Timing in Caenorhabditis elegans
Advisor: Gary Ruvkun

Rieff, Heather - NSCI
The Role of Neuregulin and erbB Receptors in Cerebellar Development
Advisor: Gabriel Corfas

Rizzuto, Carlo - VIR
Molecular Interactions in HIV-1 Entry
Advisor: Joseph Sodroski

Sabatini, Bernardo - NSCI
Calcium Control of Neurotransmitter Release at a Cerebellar Synapse
Advisor: Wade Regehr

Senatus, Patrick - NSCI
Electrophysiological and Cytochemical Properties of Rat Neostriatal Neurons in Microculture
Advisor: David Potter

Sincich, Lawrence - NSCI
Local Circuits in Primary Visual Cortex
Advisor:

Smith, Paula - NSCI
Voltage-dependent Gating of HERG Potassium Channels
Advisor: Gary Yellen

Stewart, Eric - BBS
The Role of Two Thiol-Disulfide Redox Pathways in Escherichia coli.
Advisor: Jonathan Beckwith

Stillwell, Ross - IMM
Signaling Through the CD7 T Lympocyte Receptor
Advisor:

Sudarsanam, Priya - BBS
Transcriptional Control by Snf/Swi in S. cerevisiae
Advisor: Fred Winston

Tsang, Alice - BBS
Identification of Friend of GATA-1 (FOG), an Essential Cofactor for Transcription Factor GATA-1 in Hematopoiesis
Advisor: Stuart Orkin

Van Koughnet, Kelly - NSCI
Proenkephalin Transgene Regulation in the Paraventricular Nucleus of the Hypothalamus by Lipopolysaccharide and Interleukin-1b: a Model for the Study of Neuro-immune Communication
Advisor:

Watson, Fiona - NSCI
Retrograde Signaling by Neurotrophins
Advisor: Rosalind Segal

Zeitzer, Jamie - NSCI
Physiology and Anatomy of Human Circadian Photoreception and Melatonin Regulation
Advisor: Charles Czeisler

Zhou, Heng - BBS
A Study of Transcriptional Regulation of the SUC2 Gene of S. cerevisiae : Promoter Analysis and Characterization of a New Repressor, Nrg1
Advisor: Fred Winston

Zylka, Mark - NSCI
Characterization of a Mammalian Circadian Feedback Loop
Advisor:

1998

Aggarwal, Sanjay - NSCI
Analysis of the Voltage Sensor in a Voltage-Activated Potassium Channel
Advisor:

Arany, Zoltan - BBS
E1A Oncoprotein-Targeted Transcriptional Coactivators
Advisor: David Livingston

Bader, Debra - BBS
A Molecular and Genetic Analysis of Imprinting and Methylation in the Mouse
Advisor: Philip Leder

Belliveau, Michael - NSCI
Intrinsic and Extrinsic Regulation of Cell Fate Choices in the Vertebrate Neural Retina
Advisor: Constance Cepko

Benson, Ericka - BBS
Pore Formation and Translocation by Anthrax Protective Antigen
Advisor: R. John Collier

Berger, Allison - BBS
Genetic Analysis of G Protein-Induced Neuronal Degeneration in C. elegans
Advisor: Joshua Kaplan

Berke, Joshua - NSCI
A Complex Program of Dopamine-Induced Gene Expression Identified Using Differential-Display PCR: Discovery of a Novel Inducible Cyclin
Advisor:

Brook, Adam - BBS
E2F Functions and Pathways
Advisor: Nick Dyson

Brown, Jennifer Ruth - BBS
The Role of fos Family Genes in Adaptive Neuronal Responses and Cell Proliferation
Advisor: Michael Greenberg

Buggs, Colleen - BBS
Novel Aspects of Gene Regulation by the SRY Family of DNA-Binding Proteins
Advisor:

Cheatham, Lynn - BBS
Structural and Functional Analysis of p70S6k and its Role in the Control of Cell Proliferation
Advisor: John Blenis

Chiang, Su - BBS
Genetic Analysis of the Colonization Mechanisms of Vibrio cholerae
Advisor: John Mekalanos

Clark, Rachael Ann - IMM
Lymphocyte Trafficking: Adhesive Interactions in Secondary Lymphoid Organs
Advisor: Timothy Springer

Cohen, Barak - BBS
Selection of Peptide Aptamers that Recognize and Inhibit Intracellular Proteins
Advisor: Roger Brent

Esler, William - BBS
Alzheimer's Disease b-Amyloid Peptide Assembly and Deposition in vitro
Advisor: John Maggio

Finger, Erik - BBS
Regulation of Selectin-mediated Leukocyte Adhesion
Advisor: Timothy Springer

Frank, Scott - IMM
Cloning and Characterization of ARNO, a Guanine Nucleotide Exchange Factor for the Small GTPase ARF6
Advisor: James Casanova

Garrity, Lynne - BBS
The Identification of Virulence Genes of Leishmania major by Functional Rescue
Advisor: Stephen Beverley

Gehring, Amy - BBS
Phosphopantetheinyl Transferase Catalyzed Activation of Polyketide and Nonribosomal Peptide Synthases and Deconvolution of Enterobactin and Yersiniabactin Siderophore Biosyntheses
Advisor: Christopher T Walsh

Genova, Lisa - NSCI
Amphetamine-Induced Adaptations in Striatal Neurons: Roles of Serotonin and Conditioned Stimuli
Advisor: Steven Hyman

Huang, Hsueh-Cheng - BBS
Mechanism of ATP-dependent Proteases and Role of Molecular Chaperones in Protein Degradation in Escherichia coli
Advisor: Alfred Goldberg

Hurford, Jr., Robert Kenneth - BBS
Analysis of E2F Activity in Primary Cells Deficient for pRB Family Member Proteins
Advisor: Nick Dyson

Jackman, Robin - IMM
Intracellular Trafficking of CD1 and its Consequences for Lipid Antigen Presentation
Advisor:

Jenner, Annette - NSCI
The Connectivity of Ectopic Neurons in the Neocortex and their Effects on Neuronal Size in the Thalamus: Implications for Developmental Dyslexia
Advisor: Gordon Sherman

Jones, Dana - BBS
The Human Papillomavirus E7 Oncoprotein Utilizes Multiple Mechanisms to Overcome Cellular Growth Arrest Signals
Advisor: Karl Münger

Jordan, Thomas - NSCI
Network Dynamics and their Neuromodulation: Dopaminergic Effects on Retinal Receptive Fields
Advisor: John Dowling

Kadosh, David - BBS
Evidence for Targeted Histone Deacetylation as a Mechanism of Transcriptional Repression
Advisor: Kevin Struhl

Koepp, Deanna - BBS
Analysis of Nuclear Transport Factors in Saccharomyces cerevisiae
Advisor: Pamela Silver

Kwon, David - BBS
Enzymology of the Bifunctional Glutathionylspermidine Synthetase/Amidase from Eshcerichia coli
Advisor: Christopher T Walsh

Lin, Chia-Yang - BBS
Lineage and Molecular Analysis of the Developing Chick Cerebellum
Advisor: Constance Cepko

Lin, Huamao - IMM
CD2-Mediated Signal Transduction in Human T Lymphocyte Activation
Advisor: Barbara Bierer

Liu, Karen (Qianye) - IMM
Role of ITK in T Cell Activation and Signal Transduction
Advisor: Leslie J. Berg

Lu, Wange - VIR
Pak1 Kinase: A Nck Adaptor Interacting Protein
Advisor: Bruce Mayer

Luo, Daniel Biao - BBS
Isolation and Functional Analysis of a cDNA for Human Jagged2, a Gene Encoding a Ligand for the Notch Receptor
Advisor: Jeffrey Sklar

Lupher, Jr., Mark - IMM
Identification and Characterization of the Cbl Phosphotyrosine-Binding Domain and Its Role in Negative Regulation of the ZAP-70/Syk Family of Tyrosine Kinases
Advisor:

Nelson, Heather - BPH
Somatic Mutation in Lung Cancer
Advisor:

Niethammer, Martin - NSCI
Organization of an NMDA Receptor-Associated Complex via the PDZ Domains of PSD-95
Advisor: Morgan Sheng

Novitch, Bennett - BBS
Regulation of Skeletal Muscle Differentiation by the Retinoblastoma Tumor Suppressor Protein and Cyclin-Dependent Kinase Inhibitors
Advisor: Andrew Lassar

O'Reilly, Alana - BBS
The Role of the Protein Tyrosine Phosphatase SHP-2 in bFGF Signaling in Xenopus Animal Caps
Advisor: Benjamin Neel

Petrovick, Martha - BBS
Regulation of Myeliod-Specific Genes: Analysis of Protein-Protein Interactions Involving the Transcription Factors PU.1, AML1 and C/EBPa
Advisor: Daniel Tenen

Prahalad, Murali - BBS
The Induction of Vancomycin Resistance and Crosstalk Among Bacterial Two-Component Systems
Advisor: Christopher T Walsh

Puder, Mark - VIR
Intracellular Movement and Binding of Leukotriene C4 and Glutathione Conjugates
Advisor:

Ranger, Ann - IMM
The Role of the B7 and NFAT Family Members in T Helper Cell Differentiation
Advisor: Laurie Glimcher

Reid, Russell - IMM
Complement-Immunoglobulin Interactions: A Three-Case Study
Advisor: Michael Carroll

Rietsch, Arne - BBS
Disulfide Bond Formation and Isomerization in Escherichia coli
Advisor: Jonathan Beckwith

Rohrwild, Markus - BBS
The ATP-dependent HsIVU Protease Complex from Escherichia coli
Advisor: Alfred Goldberg

Sadler, Kirsten - BBS
Components of the Signaling Pathway Leading to Cell Cycle Activation and Meiotic Maturation in Starfish Oocytes
Advisor: Joan Ruderman

Sadoulet-Puccio, Helene - BBS
Cloning and Characterization of Dystrobrevins, Dystrophin Related and Associated Proteins
Advisor: Louis Kunkel

Schwartz, Phillip - NSCI
Neurotrophins in the Regulation of Cerebellar Development
Advisor: Rosalind Segal

Sewack, Gerald - BBS
Chromatin Structure of the pS2 Promoter and its Influence on Transcription Factor Binding
Advisor: Ulla Hansen

Sholas, Maurice G. - NSCI
Changes in Primary Somatosensory Cortex Processing of Nociceptive Information Induced by Inflammation
Advisor:

Slavik, Jacqueline - IMM
Signaling through CD28 Family Receptors: An Analysis of CD80- and CD86-dependent Pathways
Advisor:

Smith, Laura - BBS
A Model for Neutrophil Differentiation Involving Synergistic Upregulation of the G-CSFR Promoter by Ras and C/EBPa
Advisor: Daniel Tenen

Stevens, Lisa - BBS
Analysis of Virulence of Pseudomonas syringae on Arabidopsis thaliana
Advisor: Frederick Ausubel

Talis, Andrea - BBS
Functions of the E6AP Ubiquitin Protein Ligase
Advisor: Peter Howley

Thompson, David Alan - BPH
HPV-16 E6 and E7 Disrupt Cell Proliferation and Apoptosis Control Mechanisms in Normal Human Cells
Advisor: Karl Münger

Tolias, Kimberley - BBS
Role of Lipid Kinases in Rac1 GTPase Signaling to the Actin Cytoskeleton
Advisor: Lewis Cantley

Tramo, Mark - NSCI
Neural Representations of Acoustic Information in Relation to Music and Voice Perception
Advisor:

Volker, Janet - BBS
Regulation of the Mammalian Transcription Factor LSF at the G0/G1 Boundary
Advisor: Ulla Hansen

Wang, Cindy Chi-Wen - BBS
Molecular Analysis of the Mouse formin Gene
Advisor: Philip Leder

West, Anne Elizabeth - NSCI
Protein Targeting in Neurons
Advisor: Kathleen Buckley

Westphal, Christoph - BBS
Ataxia-telangiectasia: A Disease of Defective Signaling
Advisor: Philip Leder

Yenush, Lynne - BBS
Essential Elements in Insulin-Stimulated Cell Growth and Survival
Advisor: Morris White

Yoder, Jeffrey - BBS
DNA Methyltransferases in Mammalian Development and Host Defense
Advisor: Timothy Bestor

Yu, Jianming - BPH
Functional and Structural Characterization of SFT, a Stimulator of Fe Transport
Advisor: Marianne Wessling-Resnick

1997

Alexiades-Armenakas, Macrene - BBS
Retinal Progenitor Cells Are Heterogeneous in Antigen Expression and the Fate of their Progeny
Advisor: Constance Cepko

Ausubel, Lara Jane - IMM
Activation of Autoreactive T Cells by Altered Peptide Ligands
Advisor: David Hafler

Bajaj, Vivek - BBS
HilA-a Transcriptional Activator of Salmonella typhimurium Invasion Genes
Advisor: Cathy Lee

Benson- Berkenblit, Gail - BBS
The Role of Hoxa-10 in Reproductive Tract Morphogenesis and Uterine Implantation
Advisor: Richard Maas

Borras-Rodriquez, Ana María - VIR
Analysis of the Promoter Elements in the Epstein-Barr Virus Lytic Switch Gene, BZLF1
Advisor: Jack Strominger

Bortvin, Aleksey - BBS
Genetic and Biochemical Analysis of SPT6 Function in the Control of Chromatin Structure in S. cerevisiae
Advisor: Fred Winston

Bricker, Angela Lowry - BBS
Control of mRNA Stability in Escherichia coli: Structure and Function of Two 5' Untranslated Regions
Advisor: Joel Belasco

Brown, Steven Andrew - BBS
Roles for Activators and Chromatin in the Regulation of Transcriptional Elongation
Advisor: Robert Kingston

Bruce, Ashley - NSCI
Characterization of an orthodenticle Homolog in the Leech and Investigation of Ectopic Gene Expression Techniques
Advisor: Marty Shankland

Campbell, Kathryn - BBS
Functional Analysis of Conserved Sequence Motifs in Polyomavirus Tumor Antigens Required for Interactions with Cellular Proteins
Advisor: Thomas Roberts

Chen, Haiyan - BBS
Regulation of Signaling Pathways in Macrophages by the Protein Tyrosine Phosphatase SHP1
Advisor: Benjamin Neel

Chen, Xin - BBS
Composition and Assembly of an Activin Response Factor during Early Xenopus Development
Advisor: Malcolm Whitman

Chiang, Ming-Ko - BBS
Identification and Characterization of Novel Extracellular Signaling Molecules in Embryonic Development
Advisor: John Flanagan

Chow, Connie Shui-Yi - VIR
Structure/Function Analysis of the Herpes Simplex Virus DNA Polymerase Subunit UL42: A Novel Processivity Factor
Advisor: Don Coen

Craiu, Abie - IMM
Analysis of the Proteolytic Steps Involved in MHC Class I Presentation of the Ovalbumin epitope SIINFEKL
Advisor: Kenneth L. Rock

Crawford, Keith Dwain - IMM
Human Peripheral Blood Dendritic Cells: Phenotype, Morphology, and Function
Advisor: Chester Alper

Elkes, Daniel Arthur - BBS
Genetic Analysis of Serotonin Regulated Behaviors in C. elegans
Advisor: Joshua Kaplan

Encinas, Jeffrey - IMM
An Analysis of the Genetic Basis for Susceptibility to Murine Experimental Autoimmune Encephalomyelitis
Advisor: Howard Weiner

Ezzeddine, Zahra Diala - BBS
Cell Type Specification in the Mammalian Retina: Developmental Plasticity of Postmitotic Progenitors Revealed by CNTF
Advisor: Constance Cepko

Farzan, Michael - IMM
The Role of Chemokine Receptors in HIV-1 and SIV Infection
Advisor: Joseph Sodroski

Fazeli, Pooya - BBS
Role of Non Receptor Tyrosine Kinases in Fcg Receptor Mediated Phagocytosis: Studies in a Heterologous System
Advisor: Brian Seed

Field, Seth Joel - BBS
Genetic Analysis of Two Mammalian Oncogenic Transcription Factors: c-fos and E2F1
Advisor: Michael Greenberg

Galvin, Katherine Margaret - BBS
Transcriptional Repression by YY1
Advisor: Yang Shi

Goff, Deborah Jeanne - BBS
Functional Analysis of the Roles of Hoxd-13 and Hoxd-11 During Chick Limb Development
Advisor: Clifford Tabin

Gorman, James - IMM
The Role of the Immunoglobulin 3'k Enhancer Element in Rearrangement and Expression of the Immunoglobulin k Light Chain Locus
Advisor: Frederick Alt

Grammer, Timothy - BBS
Characterization of the Regulation of pp70 S6 Kinase and the MAP Kinases, ERK1 and ERK2
Advisor: John Blenis

Gueiros Filho, Frederico - BBS
Genetic Studies of Leishmania
Advisor: Stephen Beverley

Halachmi, Shlomit - BBS
Characterization and Cloning of an Estrogen Receptor Coactivator
Advisor: Myles Brown

Hendrickson, Erik - BBS
Role of the rpoN-Encoded Alternative Sigma Factor in Pseudomonas syringae and Pseudomonas aeruginoas Pathogenesis
Advisor: Frederick Ausubel

Ho Pao, Chrystal L. - BBS
Generation and Analysis of Mice Deficient in a Calcium-Sensing Receptor
Advisor: Jonathan Seidman

Hoock, Thomas Carl - BBS
Lysosomal Ankyrins: Characterization of Unique Isoforms of Ankyrin-3 in the Mouse Macrophage
Advisor: Samuel Lux

Huizenga, David Everett - BBS
Isolation and Analysis of Novel Functional Single Stranded DNAs
Advisor: Jack Szostak

Jost, Christine Arlette - BBS
Functional Analysis of the p53-like Gene, NBS-1
Advisor:

Kantor, Jason - BBS
Inhibition of Tumor Cell Motility by the Metastasis Supressor Gene, NM23
Advisor: Bruce Zetter

Kim, Dennis - BBS
Enzyme Mechanism, Inhibition, and Antibiotic Resistance in the First Step of Bacterial Peptidoglycan Biosynthesis Catalyzed by MurA
Advisor: Christopher T Walsh

Konzak, Kristin Elaine - BBS
Functional Analysis of Pit-1 Isoforms
Advisor: David Moore

Koweek, Allison - BBS
Analysis of Maternal Effect Genes and daf-3 in C. elegans dauer Formation
Advisor: Gary Ruvkun

Krauss, Raul - NSCI
Studies of Nicotinic Acetylcholine Receptor Gene Expression in the Central Nervous System
Advisor: Gerald Fischbach

Lazar, Sara Whitney - BBS
Survival of Ecscherichia coli in Stationary Phase
Advisor: Roberto Kolter

Lee, Mark - BBS
The Role of the TATA-binding Protein in Transcriptional Activation
Advisor: Kevin Struhl

Lee-Fruman, Kay - IMM
Molecular Mechanisms of Lck Function in CD4 Signaling
Advisor:

Lien, Lester - BBS
Regulation of the Myeloid-cell Expressed Human gp91-phox Gene as Studied by Transfer of Yeast Artificial Chromosome Clones into Embryonic Stem Cells
Advisor: Stuart Orkin

Madison, Jon Morrow - BBS
Analysis of SPT3, a Conserved Transcription Factor, in the Control of Promoter-Specific Transcription in S. cerevisiae
Advisor: Fred Winston

Madison, Lara L. - BBS
Oxazole and Thiazole Moieties in Peptides: Post-translational Modification of Serines and Cisteines
Advisor: Roberto Kolter

McKinney, Patricia Ansel - BBS
A Specific RNA-Protein Interaction in Alfalfa Mosaic Virus: Identification of an RNA Binding Consensus Sequence and Conserved RNA Determinants
Advisor: Lee Gehrke

Moqtaderi, Zarmik - BBS
TBP-associated Factors in Saccharomyces cerevisiae
Advisor: Kevin Struhl

Morris, Jason - BBS
Cloning and Characterization of age-1, a Phosphatidylinositol 3-OH Kinase Family Member that Regulates Life Span and Life Cycle in C. elegans
Advisor: Gary Ruvkun

Morris, Mary - NSCI
Entrainment of the Mammalian Circadian Clock: Identification of Light-Induced Genes in the SCN
Advisor: Charles Weitz

Myers, Martin - BBS
The Function of Insulin Receptor Substrate-1 in Insulin Signal Transmission
Advisor: Morris White

Nascone, Nanette - BBS
The Induction and Left-Right Patterning of the Heart in Xenopus laevis
Advisor: Mark Mercola

Nelson, Craig Emory - BBS
Hox Genes and the Development and Evolution of Tetrapod Limbs
Advisor: Clifford Tabin

Peng, Cheng-Yuan - VIR
Regulation of Human Cdc25C Phosphatase
Advisor: Helen Piwnica-Worms

Phelan, Shelley - BBS
A Role for Pax-3 in Maternal Diabetes-Induced Neural Tube Defects, and Characterization of DNA Sequences which Mediate Pax-3 Binding and Transactivation
Advisor: Mary Loeken

Prinz, William - BBS
Studies on Protein Folding and Protein Export in Escherichia coli
Advisor: Jonathan Beckwith

Reid, Christopher Brian - NSCI
Cell Lineage in Mammalian Cerebral Cortex
Advisor: Christopher Walsh

Ressler, Kerry - NSCI
Odorant Receptor Organization and Information Coding in the Mouse Olfactory System
Advisor: Linda Buck

Roberts, Shannon - BBS
Identification and Analysis of Spt20: Connections to Histone Acetyltransferases and Large Transcription Complexes
Advisor: Fred Winston

Rogers, Elizabeth - BBS
Genetic Analyses of the Arabidopsis thaliana - Pseudomonas syringae Interaction
Advisor: Frederick Ausubel

Rosania, Gustavo Rafael - BBS
Spatial Control of Protrusive Activity and Cell Shape by Microtubules
Advisor: Joel Swanson

Rosen, Laura - BBS
Calcium Activation of the Ras/MAP Kinase Signaling Pathway
Advisor: Michael Greenberg

Saltsman, Kirstie Ann - BBS
The Regulation of Heat Shock Factor in the Fission Yeast, Schizosaccharomyces pombe
Advisor: Robert Kingston

Sethna, Michael - IMM
Functions of Costimulators in Humoral Immunity
Advisor: Abul Abbas

Sheen, Volney - NSCI
Transplantation Strategies for Reconstruction of Complex Neocortical Circuitry
Advisor: Jeffrey Macklis

Sodickson, Deborah Lynn - NSCI
Control of Inwardly Rectifying Potassium Channels and Voltage-Dependent Calcium Channels by G-Protein Coupled Tansmitter Receptors in Hippocampal Neurons
Advisor: Bruce Bean

Sorra, Karin Elena - NSCI
Synapse Structure, Function and Plasticity in Hippocampal Area CA1
Advisor:

Stanger, Ben - BBS
Molecular Characterization of the Cell Death Inducers Fas/APO-1 and RIP
Advisor: Philip Leder

Stubdal, Hilde - VIR
Novel Mechanism for Inactivation of the pRB-related Proteins p130 and p107 Mediated by the J-domain of SV40 large T Antigen
Advisor: James DeCaprio

Tissenbaum, Heidi - BBS
Genetic and Molecular Analysis of Genes Controlling Diapause and Longevity in Caenorhabditis elegans
Advisor: Gary Ruvkun

Tolentino, Paul - NSCI
Transcriptional and Post-Transcriptional Regulation of VIP mRNA Expression
Advisor: Lydia Villa-Komaroff

Tsai, Chin-Shaw - BPH
Transition Metals and Chemokine Gene Expression in Pulmonary Inflammation
Advisor:

Tung, Rosann - BBS
Cloning and Functional Characterization of KHS, a Novel SPS1/STE20 Homologue
Advisor: John Blenis

Uprichard, Susan L. - VIR
Expression and Assembly of the HSV DNA Replication Proteins
Advisor: David Knipe

Van Parijs, Luk - IMM
Mechanisms of Peripheral CD4+ T Cell Tolerance
Advisor: Abul Abbas

Vines, Charlotte Mary - BBS
Cloning, Localization and Expression of Rat Brain Cytoplasmic Dynein Heavy Chain
Advisor: Frank McKeon

Watson, Deborah - NSCI
Effects of the HCHWA-D Mutation on bAPP Processing, Heterogeneity of Ab Deposits, and Heparin/HSPG Binding: Implications for Alzheimer's Disease
Advisor: Dennis Selkoe

Weiger, Wendy - NSCI
Serotonergic Neurons in the Lobster: Excitatory and Inhibitory Inputs
Advisor: Edward Kravitz

Welsh, David - NSCI
Circadian Clock Neurons in Culture
Advisor:

Wen, Shih-Te - BBS
Regulation and Function of the c-Abl Tyrosine Kinase
Advisor: Rick Van Etten

Wietasch, Kristina - NSCI
Regulation of Neuronal Nicotinic Acetylcholine Receptors in the Interpeduncular Nucleus
Advisor:

Wilker, Nancy - IMM
Early Signaling Events in T Cell Activation
Advisor: Brian Seed

Xing, Jun - BBS
Regulation of CREB Activation by Nerve Growth Factor
Advisor: Michael Greenberg

Yeh, Lily - BBS
The L/S Junction-Spanning Transcripts (L/STs) of Herpes Simplex Virus Type 1
Advisor: Priscilla Schaffer

Zinkl, Gregory Martin - BBS
Cell-Laminin Interactions in the Polarization of Madin-Darby Canine Kidney (MDCK) Epithelial Cells
Advisor: Karl Matlin

1996

Ahn, Andrew - NSCI
The Membrane Cytoskeleton in Muscular Dystrophy
Advisor: Louis Kunkel

Benson, Timothy - BBS
Mechanistic and Structural Studies of UDP-N-Acetylenolpyruvylglucosamine Reductase Catalyzing the Synthesis of UDP-N-Acetylmuramic Acid
Advisor: Christopher T Walsh

Bonni, Azad - NSCI
Neurotrophic Factor Regulation of Immediate Early Gene Expression
Advisor: Michael Greenberg

Brown, Eric Jason - IMM
Mechanism of Immunosuppression by Rapamycin
Advisor: Stuart Schreiber

Chan, David - BBS
Molecular Analysis of Two Mouse Limb Mutants: Limb Deformity and Strong's Luxoid
Advisor: Philip Leder

Chang, Ted Hung-Tse - BBS
Disregulation of Mitotic Checkpoints and Regulatory Proteins by SV40 T Antigen in Human Diploid Cells
Advisor: Robert Schlegel

Cole, Rebecca Leah - NSCI
Neurotransmitter Regulation of CRE- and AP-1-Mediated Gene Expression in Rat Striatum
Advisor: Steven Hyman

Cuomo, Christina Ann - BBS
The Role of the Recombination Activating Genes, RAG1 and RAG2, in V(D)J Recombination
Advisor: Marjorie Oettinger

Dohrmann, Cord E. - BBS
The Role of TGF-b Molecules in the Establishment of the Dorsal-ventral Axis and Mesoderm Induction in Xenopus laevis and Brachydanio rerio.
Advisor: Douglas Melton

Donovan, John William - BBS
Rad51 Protein Interactions in DNA Repair and Recombination
Advisor: David Weaver

Douhan, III, John - IMM
Noncoordinate Regulation of the Human and Murine Major Histocompatibility Complex Class II Genes
Advisor: Laurie Glimcher

Frazier, David - BBS
Regulation of Herpes Simplex Virus Type 1 Latency-Associated Transcript Promoter Activity by Nerve Growth Factor and Sodium Butyrate
Advisor: Priscilla Schaffer

Gastier, Julie - BBS
Anatomy of a Pericentric Inversion and other Instances of Genomic Instability
Advisor: Geoffrey Duyk

Hanna-Rose, Wendy - BBS
Molecular Analysis and Functional Characterization of Two Transcriptional Repression Regions in Drosophila Krüppel
Advisor: Ulla Hansen

Haqq, Christopher M. - BBS
Mammalian Sexual Dimorphism: Regulation of Müllerian Inhibiting Substance Gene Expression by SRY
Advisor: Patricia Donahoe

Heng, John Edward - BBS
Ca2+ Channel Modulation of Neuronal Viability and Outgrowth
Advisor:

Himawan, Jeff - BBS
Genetic and Biochemical Analysis of the Interaction between Bacteriophage T7 DNA Polymerase and Escherichia coli Thioredoxin
Advisor: Charles Richardson

Houser-Scott, Felicia - BBS
Identification of Nucleotide Sequence and Structural Elements Required for Specific RNA-Protein Interactions in Alfalfa Mosaic Virus
Advisor: Lee Gehrke

Iyer, Vishwanath - BBS
Studies on the Constitutive Transcription of HIS3 in Saccharomyces cerevisiae
Advisor: Kevin Struhl

Jackson, Paul - NSCI
VSOAC: A Volume Sensitive Anion Channel with a Novel Function.
Advisor: Larry Benowitz

Jander, Georg - BBS
Genetic Studies on Protein Folding and Protein Secretion in Escherichia coli
Advisor: Jonathan Beckwith

Joung, Jae - BBS
Studies of Prokaryotic Transcriptional Activator Synergy and Dimerization Specificity
Advisor: Ann Hochschild

Keller, Tracy - BBS
Study of Lyme Neuroborreliosis using Polymerase Chain Reaction
Advisor: Thomas Roberts

Kim, Jae Bum - BBS
Cloning and Characterization of ADD1: Role in Adipocyte Differentiation and Fatty Acid Metabolism
Advisor: Bruce Spiegelman

Knowles, Roger - NSCI
Translocation of RNA Granules in Living Neurons
Advisor: Kenneth Kosik

LaBonne, Carole B. - BBS
FGF Generated Signals During Mesoderm Formation in Xenopus
Advisor: Malcolm Whitman

Lekutis, Christine Aldona - IMM
Human Immunodeficiency Virus Type 1 Envelope-Specific CD4+ T Lymphocyte Responses of Rhesus Monkeys
Advisor: Norman Letvin

Levin, Michael - BBS
The Molecular Basis of Left-Right Asymmetry in Embryonic Development
Advisor: Clifford Tabin

Li, Zhiying - IMM
The XRCC4 Gene Encodes a Novel Protein Involved in DNA Double-Strand Break Repair and V(D)J Recombination
Advisor: Frederick Alt

Liu, Dong - BBS
The Crystal Structure of the Zeta Isoform of the 14-3-3 Protein
Advisor: Robert Liddington

Loh, Christine - IMM
Regulation of the Cyclosporin A-Sensitive Transcription Factor NFAT1
Advisor: Anjana Rao

MacBeth, Kyle James - BBS
Identification and Characterization of an Endoribomuclease Activity of Leishmaniavirus Capsids
Advisor: Jean Patterson

Macknik, Stephen L. - NSCI
The Physiology and Perception of Visibility and Visual Masking
Advisor: Margaret Livingstone

Milne, George - BBS
The Role of Rad52 in DNA Double-Strand Break Repair and Recombination
Advisor: David Weaver

Moghal, Nadeem - BBS
Regulation of RARb Expression in Normal and Neoplastic Lung
Advisor: Benjamin Neel

Monroe-Gonzalez, James Joseph - BBS
Mechanism of Palytoxin Action on Human Osteoblast-like Cells: Studies on the Molecular Physiology of the Na+, K+-ATPase
Advisor: Armen Tashjian

Nam O, Hyun-Joo - BBS
Three Dimensional Structures of SH2 and SH3 Domains of the Abl and Shc Oncoproteins
Advisor: Christin Frederick

Newton, Elizabeth Marguerite - BBS
Regulation of Transcriptional Activation by Human Heat Shock Factor 1
Advisor: Robert Kingston

Ord, David Charles - IMM
Analysis of the Genes that Encode the CD19 and CD62L Cell Surface Proteins
Advisor:

Overly, Caroline Cannon - NSCI
Organelle Motility and Endocytic Pathways in Cultured Neurons
Advisor: Peter Hollenbeck

Peters, Bruce Nathan - NSCI
Responses to Light of Starburst Amacrine Cells in the Retina of the Rabbit
Advisor: Richard Masland

Petosa, Carlo - BBS
Crystal Structure of the Anthrax Protective Antigen
Advisor: Robert Liddington

Pogliano, Joseph Anthony - BBS
Genetic Studies on the Localization and Regulation of Escherichia coli Cell Envelope Proteins
Advisor: Jonathan Beckwith

Puglielli, Maryann Theresa - VIR
Regulation of EBNA Gene Promoters in Epstein-Barr Virus Immortalized B Cells
Advisor:

Reedquist, Kris Alan - IMM
The Fyn/Lck SH3 Domain-Binding Protein p120: Identity with the c-cbl Protooncogene Product and Participation in T Cell Receptor Signalling
Advisor:

Roca, Alfred Luis - NSCI
The Mouse Mel1a Melatonin Receptor Gene
Advisor:

Schleyer, Siew Cheng - IMM
Interaction of the chaperone calnexin with immunoglobulin heavy Chains
Advisor: Shiv Pillai

Shieh, Chi-Chang Kichiong - IMM
A Novel Adhesion Molecule on Epithelium and Endothelium Mediating Binding to Lymphocytes
Advisor: Michael Brenner

Shirra, Margaret - BBS
Characterization of DNA-Binding and Oligomerization Properties of the Mammalian Transcription Factor LSF
Advisor: Ulla Hansen

Solomon, Keith Randall - IMM
Glycosylphosphatidylinositol (GPI)-Anchored Proteins Expressed on Lymphocytes
Advisor: Robert Finberg

Spiro, David Jonathan - BBS
Regulation of Early Endosomal Sorting by ADP-Ribosylation Factors and Phosphatidylinositol 3-Kinases
Advisor: Marianne Wessling-Resnick

Tontonoz, Peter - BBS
PPARg: A Dominant Regulator of Adipocyte Gene Expression and Differentiation
Advisor: Bruce Spiegelman

Zavacki, Ann Marie - BBS
Defining Mechanisms of Thyroid Hormone Action
Advisor: P. Reed Larsen

1995

Akhtar, Irfan - PATH
Biology of Ia-restricted Autoreactive T cell clones that inhibit Insulin Dependent Diabetes Mellitus (IDDM) in NOD mice
Advisor:

Bachelder, Robin - VIR
Characterization of the CD4-Specific Antibody Response of a Recombinant Soluble CD4-Immunized, HIV-1-Infected Human through the Construction of a Combinatorial Fab Library
Advisor: Norman Letvin

Baradaran, Khandan - VIR
Identification and Characterization of a Novel HSV-1 Origin Binding Protein
Advisor: Priscilla Schaffer

Bunker, Christopher - BBS
Transcriptional Activator Functions in Genomic Chromatin and Repressor Functions of Polycomb Group Proteins
Advisor: Robert Kingston

Carr, Michelle - IMM
The Role of C-C Chemokines in Transendothelial Migration of T Lymphocytes
Advisor: Timothy Springer

Chang, Belinda - NSCI
Opsin Phylogeny and Evolution
Advisor: N.E. Pierce

Cheng, Hwai-Jong - BBS
Identification, Cloning and Characterization of ELF-1, a Member of a New Ligand Family Implicated in Development of the Topographic Retinotectal Projection Map
Advisor: John Flanagan

Chiang, Anne - BBS
The Interaction of Polycomb Protein with the Bithorax Complex in Drosophila melanogaster
Advisor: Welcome Bender

Chicurel, Marina - NSCI
RNA Localization and RNA-Cytoskeletal Interactions in Neurons
Advisor: Huntington Potter

Curtin, Kathryn - VIR
Regulated Nuclear Entry of the period Protein Contributes to a Circadian Clock in Drosophila
Advisor:

Epperson, Diane - IMM
Direct Activation of Human CD8 T Lymphocytes by Allogenic Endothelial Cells
Advisor:

Fingar, Diane - BBS
Identification of Signal Transduction Pathways Involved in Insulin Regulated Glucose Transport
Advisor: Morris Birnbaum

Freeman, Robert - VIR
Molecular Cloning and Characterization of the SH2 Domain-containing Protein Tyrosine Phosphatase SH-PTP2
Advisor: Benjamin Neel

Fruman, David - IMM
Molecular Mechanisms of Action of the Immunosuppressive Drugs Cyclosporin A, FK506 and Rapamycin
Advisor:

Fulwiler, Carl - NSCI
Genetic Analysis of Retinal Development in Zebrafish
Advisor: John Dowling

Gansheroff, Lisa - BBS
Characterization of SPT7, a Gene Important for Transcription in S. cerevisiae
Advisor: Fred Winston

Gillette, Michael - NSCI
Gamma-Aminobutyric Acid- and Glycine-Activated Currents and their Modulation in the Rod Bipolar Cell of the Rabbit Retina
Advisor: Raymon Dacheux

Goad, Dale - BBS
Down-Regulation of Parathyroid Hormone Receptor Expression in SaOS-2 Human Osteoblast-like Cells by Insulin-like Growth Factor-I
Advisor: Armen Tashjian

Grant, Ethan - IMM
The Involvement of Exogenous Antigen, Ubiquitin, and the Proteasome in MHC Class I Antigen Presentation
Advisor: Kenneth L. Rock

Han, Bomie - BBS
Identification of Ligand Binding Sites in the Thyrotropin-Releasing Hormone Receptor
Advisor: Armen Tashjian

Hann, Louane - BBS
The Roles of 5'- and 3'- Untranslated Regions in Alfalfa Mosaic Virus RNA Translation
Advisor: Lee Gehrke

Hirschhorn, Joel - BBS
Genetic and Molecular Analysis of Histones and SNF/SWI Proteins: Effects on Chromatin Structure and Transcription in S. cerevisiae
Advisor: Fred Winston

Hooper, Jay - VIR
Analysis of the Mechanism of Reovirus Entry into Cells
Advisor: Bernie Fields

Hudson, Amy - BBS
Insulin-Responsive Glucose Transport and Regulated Secretion
Advisor: Morris Birnbaum

Hung, Albert - NSCI
Regulation of Expression and Processing of the b-Amyloid Precursor Protein of Alzheimer's Disease
Advisor: Dennis Selkoe

Johnson, Mark - NSCI
Electrophysiological and Cytochemical Properties of Rat Mesopontine Serotonergic Neurons in Culture
Advisor: David Potter

Kaushal, Sunjay - BBS
Regulatory Networks of Muscle Gene Activation
Advisor: Nadia Rosenthal

Kelley, Clair - BBS
The Induction of Hematopoiesis in the Early Xenopus Embryo
Advisor: Leonard Zon

Klein, Charles - BBS
Mechanisms of Transcriptional Induction in Yeast
Advisor: Kevin Struhl

Kramer, Martha - VIR
Quantification of Herpes Simplex Virus DNA and Transcripts during Latent Infection in Mouse Trigeminal Ganglia by Reverse Transcriptase PCR
Advisor: Don Coen

Kundra, Vikas - BBS
Signal Transduction Pathways Involved in Platelet Derived Growth Factor-BB Mediated Chemotaxis
Advisor: Bruce Zetter

Langston, Alexander - BBS
Regulation of Vertebrate Hox Genes by Retinoic Acid
Advisor:

Laning, Joseph - IMM
Biochemical and Functional Characterization of the Murine b-chemokine, TCA3
Advisor: Martin Dorf

Lee, Frederick - BBS
Analysis of pregnancy-dependent mammary neoplasia in MMTV int-2/FGF-3 transgenic mice
Advisor: Philip Leder

Lee, Jeng-Shin - VIR
Transcriptional Regulation by Yin-Yang 1 and Adenovirus E1A
Advisor: Yang Shi

Lee, Jie-Oh - BBS
Crystal Structure of the I Domain from the a Subunit of Integrin CR3 (CD11b/CD18)
Advisor: Robert Liddington

Li, John - VIR
Construction and Characterization of Recombinant Simian/Human Immunodeficiency Virus (SHIV) Expressing the HIV-1 Envelope Glycoproteins
Advisor: Joseph Sodroski

Liu, Vivian - BBS
G1 and S phase DNA Damage Checkpoints Induced by Ionizing Radiation in Normal Human and Ataxia Telangiectasia Cells
Advisor: David Weaver

Martinez, Camilo - NSCI
Molecular Regulation of Corticotropin Releasing Hormone Gene Expression by the Protein Kinase A Pathway and Glucocorticoids
Advisor: Joseph Majzoub

McCall, Kimberly - BBS
Analysis of Regulatory Mechanisms in the Drosophila Bithorax Complex
Advisor: Welcome Bender

McNamee, Helen - BBS
Control of Inositol Lipid Signaling by Extracellular Matrix and Integrins
Advisor: Donald Ingber

Melnick, Michael - BBS
Structure/Function Analysis of Drosophila-raf and corkscrew
Advisor: Norbert Perrimon

Merzdorf, Christa - BBS
Formation of Functional Tight Junctions in Early Embryonic Development of Xenopus
Advisor: Daniel Goodenough

Milne, Jill - BBS
Entry of Anthrax Toxin into Mammalian Cells: Structure and Role of Protective Antigen
Advisor: R. John Collier

Miranti, Cynthia - BBS
How Signaling Pathways Regulate c-fos Transcription
Advisor: Michael Greenberg

Morris, Robert - BBS
Axonal Transport of Mitochondria
Advisor: Peter Hollenbeck

Nadeau, Kari - BCMP
Biochemical Studies on Protein Folding Chaperones: Hsp90 and Cyclophilin and on Trypanosomal Enzymes: Trypanothione and Glutathionylspermidine Synthetases
Advisor: Christopher T Walsh

Navia, Bradford - NSCI
Molecular Analysis of the Region Surrounding the X-Linked Retinitis Pigmentosa (RP3) Locus in Xp21.1
Advisor:

Price, Edward Royden - BBS
Cyclophilin B: Cloning, Trafficking and Interactions with Calcineurin
Advisor: Frank McKeon

Ralph, Walter - BBS
Regulation of Herpes Simplex Virus Type 1 Gene Expression by Viral and Cellular Factors
Advisor: Priscilla Schaffer

Reinertsen, Kerry - BBS
Characterization of a Role for Platelet-Derived Growth Factor in Early Mammalian Development
Advisor: Charles Stiles

Renjifo, Boris - VIR
Human T-cell Leukemia Virus Type I (HTLV-I): Pathogenesis of Tropical Spastic Paraparesis/HTLV-I-associated Myelopathy (TSP/HAM)
Advisor: Myron Essex

Rivera-Gonzalez, Ramon - BBS
Temporal Regulation of Herpes Simplex Virus Type 1 Gene Expression
Advisor: Neal DeLuca

Rooney, John - BBS
Regulation of the Interleukin 2 and Interleukin 4 Genes in Murine T Helper 1 and T Helper 2 Cell Clones
Advisor: Laurie Glimcher

Saez, Enrique - BBS
Characterization of the Role of c-fos in Cancer Development
Advisor: Bruce Spiegelman

Schaefer, Brian - IMM
Control of Restricted Epstein-Barr Virus Latency in Burkitt's Lymphoma Cell Lines
Advisor: Jack Strominger

Schoenberg Fejzo, Marlena - BBS
Cytogenic and Molecular Analysis of Chromosomal Translocations in Uterine Leiomyoma
Advisor: Cynthia Morton

Shaw, Sunil - IMM
Molecular Cloning and Functional Studies of aE, a Novel Mucosal Lymphocyte Integrin Subunit
Advisor: Michael Brenner

Shepherd, Gordon - NSCI
Components of Adaptation in Saccular Hair Cells of the Bullfrog, Rana catesbeiana
Advisor: David Corey

Shifrin, Victor - BBS
Post-transcriptional and Post-translational Modifications of Non-transmembrane Protein Tyrosine Phosphatase PTP-1B
Advisor: Benjamin Neel

Shima, David - BBS
Identification of Vascular Endothelial Growth Factor (VEGF) as an Oxygen-Regulated Mediator of Ocular Angiogenesis
Advisor: Patricia D'Amore

Soto, Martha - BBS
Characterization of the Distal Bithorax Complex and Phenotypic Studies of Polycomb Group Genes
Advisor: Welcome Bender

Staknis, David - BBS
Protein-pre-mRNA Interactions during Mammalian Spliceosome Assembly
Advisor: Robin Reed

Sydor, Anne - NSCI
The Role of Cytoskeletal Proteins Talin and Vinculin in Neuronal Growth Cone Motility.
Advisor: Daniel Jay

Telfer, Janice - IMM
A GTP-binding Protein Associated with CD4
Advisor: Christopher Rudd

Tong, Xiao - BBS
Genetic and Biochemical Study of Epstein-Barr Virus Nuclear Protein 2 and Associated Cellular Proteins
Advisor: Elliott Kieff

Valentine, Doreen - NSCI
Spatial Perception and Sensorimotor Integration: The Role of the Superior Colliculus in the Echolocating Bat, Eptesicus fuscus
Advisor:

van Heeckeren, Willem - BBS
Two Studies Related to Transcriptional Regulation in the Budding Yeast and the Fission Yeast
Advisor: Kevin Struhl

Verhey, Kristen - BBS
Subcellular Trafficking of the GLUT4 Glucose Transporter in Fibroblasts and Adipocytes
Advisor: Morris Birnbaum

Vincent, Alice - BBS
ATF/CREB Proteins in Saccharomyces cerevisiae
Advisor: Kevin Struhl

Yaglom, Julia - BBS
Studies of the degradation pathway of Cln3, a G1 cyclin from Saccharomyces cerevisiae
Advisor: Daniel Finley

Yeh, Jih-I - BBS
Studies on the Physiology of Glucose Transporter Proteins
Advisor: Morris Birnbaum

Yoffee, Kenneth - BBS
Examination of wingless Signaling and Regulation in Drosophila
Advisor: Norbert Perrimon

Zhang, Wei - IMM
Generation and Analysis of Calcineurin Aa Deficient Mice
Advisor: Jonathan Seidman

1994

Agarwal, Sadhana - VIR
Regulation of Post-Translational Modifications of c-fos and c-jun
Advisor: Thomas Roberts

Altshuler, David - BBS
Endogenous Retinal Activities that Influence the Development of Rod Photoreceptors in vitro
Advisor: Constance Cepko

Bennett, Maria - BBS
Identification, Characterization and Cloning of Mammalian Spliceosomal Components
Advisor: Robin Reed

Binari, Richard - BBS
Analysis of a Unique Segmentation Phenotype in Drosophila melanogaster
Advisor: Norbert Perrimon

Blotnick, Srully - BBS
T Lymphocytes Synthesize and Export Heparin-Binding Epidermal Growth Factor-Like Growth Factor and Basic Fibroblast Growth Factor, Mitogens for Vascular Cells and Fibroblasts: Differential Production and Release by CD4+ and CD8+ T Cells
Advisor: Michael Klagsbrun

Bradbury, Laura - IMM
The CD19 Signal Transduction Complex in B Cells
Advisor:

Burstein, Harold - IMM
Regulation and Functions of Interleukin-4 During In Vivo Immune Responses
Advisor: Abul Abbas

Cadd, Tamarra - BBS
Identification, Characterization and Expression of the Capsid Protein of Leishmania RNA Virus LRV1-4
Advisor: Jean Patterson

Cepek, Karen - IMM
Characterization of T Lymphocyte Adhesion to Mucosal Epithelial Cells: Role of Integrin aEb7 and E-cadherin
Advisor: Michael Brenner

Chi, Nai-Wen - BCMP
Biochemical and Genetic Characterization of MSH1, a Mitochondrial Protein of Saccharomyces cerevisiae that Binds to DNA Mismatches.
Advisor: Richard Kolodner

Choy Tomlinson, Lisa - BBS
Investigation of the Alternative Pathway of Complement in the Biology of white and brown adipocytes
Advisor: Bruce Spiegelman

Chung, Richard - NSCI
p53, A Bifunctional Transcriptional Regulatory Protein Inactivated in Human Astrocytic Tumors
Advisor: Bernd Seizinger

Collazo, Diana - BCMP
Role of Neurotrophin-3 and TrkC in Rat Hippocampal Development in vitro
Advisor:

Collins, Tassie - IMM
Analysis of the Role of Lck in CD4 Functions
Advisor:

Derman, Alan - MICRO
Escherichia coli Alkaline Phosphatase Lacking its Signal Sequence: Folding in the Cytoplasm and Export to the Periplasm
Advisor: Jonathan Beckwith

Diamond, Michael - BBS
The Structure, Function, and Regulation of the Leukocyte Integrin Mac-1 (CD11b/CD18)
Advisor: Timothy Springer

Dunn, Michael - BCMP
Mechanism of Action of Cyclopamine, A Steroidal Vertebrate Teratogen
Advisor: David Moore

Edmonson, Paul - VIR
Development of a Simian Immunodeficiency Virus (SIV) Pathogen
Advisor:

Finch, Elizabeth - NSCI
Inositol Trisphosphate-Mediated Calcium Release: Kinetics and Regulation by IP3, Calcium, and ATP
Advisor: Stan Goldin

Hahn, William - IMM
The Role of the CD2 Glycoprotein in T Cell Activation and Adhesion
Advisor:

Hall, Kathryn - BBS
Complementation and Chromosomal Localization of Mutants of V(D)J Recombination and Double-Strand Break Repair
Advisor: David Weaver

Harbury, Pehr - BCMP
Protein Design of Coiled Coils
Advisor:

Heyeck, Stephanie - IMM
Isolation, cloning, and characterization of a novel developmentally regulated T cell-specific tyrosine kinase, TSK
Advisor: Leslie J. Berg

Hotamisligil, Gökhan - BCMP
Tumor Necrosis Factor-a: A Key Component of the Obesity-Diabetes Link
Advisor: Bruce Spiegelman

Jean, Serge - MICRO
Activation of Herpes Simplex Virus Type 1 Late Gene Expression during Lytic Infection
Advisor: David Knipe

Jesaitis, Lynne - BBS
Molecular Characterization and Tissue Distribution of the Tight Junction Protein ZO-2
Advisor: Daniel Goodenough

Kassner, Paul - IMM
Analysis of the Integrin a4 Cytoplasmic Domain: Role in Adhesion and Post-Ligand Binding Events
Advisor: Martin Hemler

Krueger, Neil - IMM
Molecular and Genetic Analysis of the Protein Tyrosine Phosphatase Gene Family
Advisor: Haruo Saito

Ku, Po - BBS
Regulation and Role of Basic Fibroblast Growth Factor in Subleathal Injury in Vitro and in Vivo
Advisor: Patricia D'Amore

Kuldell, Natalie - BBS
Molecular Mechanisms of Transcriptional Regulation at the Phage l Promoter, PRM
Advisor: Ann Hochschild

Laham, Lorraine - BBS
The Regulation of Gelsolin and Actin Interactions by Adenine Nucleotides
Advisor: Paul Janmey

Larson, Jeffrey - BBS
Mechanism of Activation of Human Heat Shock Factor
Advisor: Robert Kingston

Lewis, Susan - NSCI
Cytokine Regulation of Neuronal Gene Expression in Sympathetic Neurons and a Neuroblastoma Cell Line
Advisor: Steven Hyman

Lin, Chung-Wu - MICRO
Guanosine-RNA Interactions
Advisor: Jack Szostak

Link, Andrew - BBS
Experimental Tools for the Analysis of Genomes: Applications to Escherichia coli
Advisor: George Church

Magovcevic- Liebisch, Ivana - BBS
Characterization, Localization and Expression of G Proteins, and their Potential Role in the Human Inner Ear
Advisor: Cynthia Morton

Marsh-Armstrong, Nicholas - NSCI
Retinoic Acid and the Patterning of the Zebrafish Retina and Trunk
Advisor:

Musacchio, Michele - BBS
Identification of a New Group of Immunoglobulin Superfamily Genes Expressed in the Central Nervous System of Drosophila melanogaster
Advisor: Norbert Perrimon

Myrick, Kyl - BBS
Molecular Genetic Analyses of the Replication of Primate Immunodeficiency Viruses
Advisor: Joseph Sodroski

Ofori-Darko, Ernest - BBS
Biochemical and Cellular Actions of Thrombin on Human Osteoblast-Like SaOS-2 Cells
Advisor: Armen Tashjian

Ottemann, Karen - MICRO
Structure-Function Analysis of the ToxR Transmembrane Regulatory Protein
Advisor: John Mekalanos

Ozelius, Laurie - BBS
Definition of the region of human chromosome 9q containing a dystonia gene
Advisor: Xandra Breakefield

Potrebic, Sonja - NSCI
The Role of Serotonin in the Modulation of Nociception by the Rostral Ventromedial Medulla of the Rat
Advisor:

Qin, Xiao-Qiang - BBS
The Role of RB-E2F Complexes in the RB-Mediated Growth Suppression
Advisor: David Livingston

Ruiz, Maria - BBS
The Cloning of an Olfactory Channel from Mouse Heart
Advisor:

Satterberg, Brett - BCMP
G1 cell cycle arrest in S. cerevisiae
Advisor: Elaine Elion

Schott, Eric - BBS
Mutliple Genes Regulate Pathogenicity Determinants in Pseudomonas cichorii
Advisor: Frederick Ausubel

Shamah, Steven - BCMP
Functional Analysis of Platelet-Derived Growth Factor Using Dominant-Negative Mutations
Advisor: Charles Stiles

Shaw, Leslie - BBS
Regulation of a6b1 Integrin Function by the Cytoplasmic Domains of the a6 Subunit
Advisor: Arthur Mercurio

Shirodkar, Suman - VIR
Functional Interactions of the Transcription Factor E2F with Cellular Proteins
Advisor: David Livingston

Smiley, Stephen - BBS
Analysis of Transgenic Mice Expressing MHC Class II Ab Molecules with Truncated Cytoplasmic Domains
Advisor: Laurie Glimcher

Staunton, Jane - MICRO
Non-V(D)J Recombination and DNA Repair Processes in the Scid Mouse
Advisor: David Weaver

Tang, Terry - BBS
Signal Transduction by the SH2-containing Protein Tyrosine Phosphatase SH-PTP2
Advisor: Benjamin Neel

Wagner, Kimberly - BBS
Mechanisms Controlling Cytosolic Free Calcium Concentration in Single GH4C1 Rat Pituitary Cells
Advisor: Armen Tashjian

White, Thomas - BBS
Molecular Cloning and Functional Analysis of Connexins Expressed in the Vertebrate Lens
Advisor: Daniel Goodenough

Williams, Nidhi - BCMP
Signal Transduction Pathways Involving the Raf-1 Kinase
Advisor: Thomas Roberts

Winkler, David - BBS
Regulation of p56lck N-Terminal Seryl Phosphorylation Regulates the p56lck Kinase and Src Homology Two Domains
Advisor: Christopher T Walsh

Xu, Yang - IMM
Developmental Regulation and Function of a Tissue Specific LIM-Homeobox Gene
Advisor: Frederick Alt

Zhang, Jue Jillian - BBS
Studies of a Germline Promoter in the Murine IgH Constant Region and Its Involvement in Class Switch Recombination
Advisor: Frederick Alt

Zhu, Zhimin - BCMP
Intracellular Localization of HSV-1 Immediate-Early Regulatory Proteins: Cooperativity among ICP0, ICP4 and ICP27
Advisor: Priscilla Schaffer

1993

Alberta, Julia - BBS
Selective Degradation of an Immediate Early mRNA
Advisor: Charles Stiles

Barondess, James - BBS
Envelope Proteins Involved in Cell Division and Lysogenic Conversion
Advisor: Jonathan Beckwith

Bartel, David - VIR
RNA Recognition and Catalysis: I. The HIV Rev-RRE Interaction II. New Ribozymes from Random Sequences
Advisor: Jack Szostak

Birch, Kimberly - BCMP
The Signal Transduction Mechanism of Thrombin-Stimulated von Willebrand Factor Secretion in Human Umbilical Vein Endothelial Cells
Advisor:

Bishop, Amy - BBS
The Role of Methoxatin (PQQ) in the Respiratory Burst of Phagocytes
Advisor: Paul Gallop

Brightman, Shannon - BBS
Molecular Cloning and Characterization of IC47: An Inducible Membrane-Associated Protein
Advisor: Bruce Zetter

Cardozo, David - NSCI
Electrophysiology of Dissociated Midbrain Dopamine Neurons
Advisor: David Potter

Casaz, Paul - VIR
Regulation of Transcription by Simian Virus 40 Large Tumor Antigen
Advisor: Ulla Hansen

Chen, Rey-Huei - CMP
Signal Transduction from Cytoplasm to Nucleus by MAP Kinase and RSK
Advisor: John Blenis

Chung, Jongkyeong - CMP
Characterization of two families of growth-regulated S6 kinases, 70kd S6 kinase and RSK
Advisor: John Blenis

Cormack, Brendan - BBS
The TATA-Binding Protein: A Mutational Analysis
Advisor: Kevin Struhl

de Fougerolles, Antonin - IMM
Characterization of Leukocyte Integrin LFA-1 (CD11a/CD18) Counter-receptors: Intercellular Adhesion Molecules (ICAM) -2, and -3
Advisor: Timothy Springer

Dewdney, Julia - BBS
Light Regulation of Glyceraldehyde-3-phosphate Dehydrogenase Genes of Arabidopsis thaliana
Advisor: Howard Goodman

Fath, Michael - MICRO
Studies on the Secretion of Colicin V
Advisor: Roberto Kolter

Feany, Mel - NSCI
Molecular Analyses of Synaptic Vesicle Proteins/Genetic and Molecular Studies of Drosophila Learning Mutants
Advisor: Kathleen Buckley

Frangioni, John - CMP
Structure and Function of the Nontransmembrane Protein Phosphotyrosine Phosphatase 1B (PTP-1B)
Advisor: Benjamin Neel

Guevara, Pablo - MICRO
Cloning and characterization of the rpoN gene of the phytopathogen Pseudomonas syringae pv. maculicola
Advisor: Frederick Ausubel

Hall, Sharynn - BCMP
Homologous Pairing Proteins Involved in RecE Pathway Recombination of Escherichia coli Biochemical Characterization of ExoVIII and RecT Recombination Activities
Advisor: Richard Kolodner

Heald, Rebecca - CMP
Regulation of Nuclear Lamina Disassembly in Mitosis
Advisor: Frank McKeon

Heginbotham, Lise - NSCI
Identification and Molecular Characterization of a Potassium Channel Pore
Advisor: Roderick MacKinnon

Hosler, Betsy - BCMP
Characterization of the Zinc Finger Gene Rex-1 (Zfp-42) whose Expression is Reduced in Murine F9 Embryonal Carcinoma Cells Treated with Retinoic Acid
Advisor:

Huertas, Pedro - BBS
Modulation of Signal Transduction of the Insulin Receptor by the Lipid Membrane Environment
Advisor: C. Ronald Kahn

Johnson, Randall - BBS
Genetic Analyses of AP-1 Factors: Gene Targeting of c-fos and c-jun
Advisor: Bruce Spiegelman

Klingensmith, John - BBS
Genetic Dissection of an Intercellular Signalling Pathway in Drosophila Pattern Formation
Advisor: Norbert Perrimon

Kobierski, Linda - NSCI
Proenkephalin Gene Expression: Mechanisms of cAMP Regulation
Advisor: Michael Comb

LaSalle, Janine - IMM
The Induction of T Cell Clonal Anergy by T Cell Presentation of a Human Autoantigen
Advisor: David Hafler

Levinson, Douglas - BBS
Molecular Characterization of Transgene-Induced Immunodeficiency in B-less Transgenic Mice
Advisor: Philip Leder

Lien, Lyndon - BBS
Characterization of Human Microtubule-Associated Protein 1B and Analysis of it as a Candidate Gene for Spinal Muscular Atrophy
Advisor: Louis Kunkel

Lo, Su-Hao - BBS
Molecular Cloning and Functional Studies of the Actin-binding and SH2 Domain-containing Protein Tensin
Advisor:

Marquardt, John - BCMP
Studies of the Enzymes Involved in UDP-N-acetylmuramic Acid Biosynthesis
Advisor: Christopher T Walsh

McClatchey, Andrea - BBS
The Role of the Voltage-Gated Skeletal Muscle Sodium Channel in Inherited Neuromuscular Disease
Advisor: James Gusella

McMorrow, Isabel - BBS
Structural and Functional Studies of a Human Nuclear Pore Complex Protein
Advisor: Brian Burke

Michaud, Susan - BBS
Characterization of the Early Steps in Mammalian Spliceosome Assembly
Advisor: Robin Reed

Morin, Merribeth - VIR
Pathogenesis of Reovirus Infection in the Lungs
Advisor: Bernie Fields

Nardone, Julie - NSCI
Site-Directed Mutagenesis of a B2 Bradykinin Receptor
Advisor: David Potter

Nibert, Max - MICRO
Structure and Function of Reovirus Outer Capsid Proteins as they Relate to Early Steps in Infection
Advisor: Bernie Fields

Nirenberg, Sheila - NSCI
Targeted Ablation of Diverse Cell Types in the Nervous System: a Method for Blocking Cell-Cell Interactions in Vivo
Advisor: Constance Cepko

Oh, Suk - BBS
Structure and Expression of Non-Fibrillar Collagens XII and XVIII in Mice
Advisor: Bjorn Olsen

Papoulas, Ophelia - BBS
Biochemical Characterization of the c-Myc Oncoprotein
Advisor: Robert Kingston

Plopper, George - BBS
Isolation of Focal Adhesion Complexes that Retain Chemical Signalling Activity
Advisor: Donald Ingber

Pogliano, Kit - MICRO
A Genetic Analysis of Protein Export in Escherichia coli
Advisor: Jonathan Beckwith

Prentice, Holly - VIR
Characteriztion of Heat Shock Factor and Mammalian Promoter Elements in the Fission Yeast Schizosaccharomyces pombe
Advisor: Robert Kingston

Racoosin, Esther - BBS
Characterization of Macropinocytosis in Mouse Macrophages
Advisor: Joel Swanson

Ryder, Elizabeth - BBS
Migration patterns of clonally related granule cells and their progenitors in the developing chick cerebellum
Advisor: Constance Cepko

Satterthwaite, Anne - BBS
Structure and Regulation of the Human CD34 Gene
Advisor: Daniel Tenen

Saunders, Kim - BBS
An In Vitro Model for the Study of Cell-Cell Interactions: Application to the Blood Vessel Wall
Advisor: Patricia D'Amore

Silverman, Jared - MICRO
Mutational Analysis of the Diphtheria Toxin Translocation Domain
Advisor: R. John Collier

Swartz, Kenton - NSCI
Regulation of Neuronal Ca Channels by Neurotransmitters, G Proteins and Kinase C
Advisor: Bruce Bean

Thompson, Margaret - NSCI
Regulation of c-fos Transcription by Calcium
Advisor: David Potter

Tishkoff, Daniel - BBS
Genetic Analysis of Sep1, a Gene Required for Meiotic Recombination and Cell-Cycle Progression in Saccharomyces cerevisiae
Advisor: Richard Kolodner

Wurgler-Murphy, Susannah - BCMP
Deoxyguanosine Triphosphate Triphosphohydrolase of Escherichia coli
Advisor: Charles Richardson

Xia, Kai - VIR
Phosphorylation of the HSV-1 Major Regulatory Protein ICP4
Advisor: David Knipe

Yan, WenLiang - BBS
Genetic and Biochemical Analyses of Neuronal Ceroid Lipofuscinoses
Advisor: James Gusella

Yang, Junping - BCMP
Molecular Cloning and Regulation of the Thyrotropin-Releasing Hormone Receptor in Rat Pituitary Lactotrope Cells
Advisor: Armen Tashjian

Yorgey, Peter - MICRO
The Biosynthesis and Structure of Microcin B17, A Novel DNA Gyrase Inhibitor
Advisor: Roberto Kolter

Zambrano, Maria - BBS
Escherichia coli with a Growth Advantage in Stationary Phase
Advisor: Roberto Kolter

Zheng, Xiao-Feng - BCMP
Regulation of Cyclin B/cdc2 Kinase Activity
Advisor: Joan Ruderman

DMS Student Body

2014-2015 - 655 students

 

Women: 331 (51%)

Men: 324 (49%)

 

Underrepresented Minority: 61 (9%)

 

Domestic: 512 (78%)

International: 143 (22%)

 

PhD: 600 (92%)

MD-PhD: 55 (8%)

 

BIG*: 15 (2%)

BBS: 358 (55%)
Immunology: 72 (11%)

Neuroscience: 123 (19%)

SHBT*: 20 (3%)

Virology: 67 (10%)

 

*These programs became a part of DMS in the Fall 2012. The number of students listed are DMS students only, students that are enrolled before the program became part of DMS are not included.


© 2013 by the President and Fellows of Harvard 
College