Completed Dissertations

The principle focus of the curriculum is the doctoral dissertations. After selection of a dissertation advisor and completion of the Preliminary Examination, a Dissertation Advisory Committee is set up to advise and support the student. This committee meets with the student every 9 months until the dissertation is written. The dissertation is then defended and submitted to the University registrar in fulfillment of the Ph.D. degree requirements. The dissertation may substantially draw on research publications, but it must conform to the guidelines in The Form of the Doctoral Dissertation. Degrees are awarded in June, November, and March.

 

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993

2014

Chu, Yunxiang
The Role of Protein Kinase C in Short-Term Synaptic Plasticity
Advisor: Wade Regehr

Fisek, Mehmet
Connectivity and computations in higher-order olfactory neurons in Drosophila
Advisor: Rachel Wilson

Garst Orozco, Jonathan
LEARNING-RELATED CHANGES IN THE FUNCTIONAL CONNECTIVITY WITHIN THE ZEBRA FINCH SONG-CONTROL CIRCUIT
Advisor: Bence Ölveczky

Lehrman, Emily
Innate immune molecules direct microglia-mediated developmental synaptic refinement
Advisor: Beth Stevens

Liu, Wendy
Dissecting Olfactory Circuits in Drosophila
Advisor: Rachel Wilson

Luth, Eric
Physiological and Pathological Characterization of Alpha-Synuclein Oligomers
Advisor: Dennis Selkoe

Stoppel, David
Social Behavior and Gene Expression Disturbances in Mouse Models of Angelman Syndrome and Idic15 Autism
Advisor: Matthew Anderson

Thanawala, Monica
Control of Neurotransmitter Release Properties by Presynaptic Calcium
Advisor: Wade Regehr

Vujovic, Nina
Functional organization of the circadian timing system
Advisor: Clifford Saper

2013

Bialas, Allison
Initiating Complement-dependent Synaptic Refinement: Mechanisms of Neuronal C1q Regulation
Advisor: Beth Stevens

Choi, Eun Young
The Organization of Corticostriatal Connectivity in the Human Brain
Advisor: Randy Buckner

Eisner, Adriana
Phosphatome RNAi Screen Identifies Eya1 as a Positive Regulator of Hedgehog Signal Transduction
Advisor: Rosalind Segal

Feliu-Mojer, Monica
Coupling the small GTPase Rab3 to the Synaptic Vesicle Cycle
Advisor: Joshua Kaplan

Ferrero, David
Olfactory control of instinctive behaviors
Advisor: Stephen Liberles

Ibarra, Yessenia
Characterization of human TRPA1 and TRPV1 channels in response to naturally occurring defensive compounds
Advisor: David Clapham

LeBlanc, Jocelyn
Critical period plasticity and sensory function in a neuroligin-3 model of autism
Advisor: Michela Fagiolini

Lou, Shan
DEVELOPMENT AND FUNCTIONS OF C-LOW-THRESHOLD MECHANORECEPTORS
Advisor: Qiufu Ma

Malik, Athar
Genome-wide identification and characterization of stimulus-responsive enhancers in the nervous system
Advisor: Michael Greenberg

Mardinly, Alan
Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons
Advisor: Michael Greenberg

Mejia, Luis
Interaction Proteomics of Autism Spectrum Disorder- and Intellectual Disability-Associated Proteins Identifies A Novel Hap1-Tsc1 Signaling Link That Controls Neuronal mTORC1 Signaling and Pyramidal Neuron Morphogenesis
Advisor: Azad Bonni

Quast, Kathleen
Functional Development and Plasticity of Parvalbumin Cells in Visual Cortex: Role of Thalamocortical Input
Advisor: Takao Hensch

Rice, Heather
Regulation of the proteolytic processing and function of Amyloid Precursor Protein by candidate ligands
Advisor: Dennis Selkoe

Sadegh, Cameron
Directed differentiation of mouse embryonic stem cells into neocortical output neurons
Advisor: Jeffrey Macklis

Salogiannis, John
Regulation of excitatory synapse development by the RhoGEF Ephexin5
Advisor: Michael Greenberg

Van't Veer, Ashlee
Role of Kappa-Opioid Receptors in Stress-Induced Behaviors
Advisor: William Carlezon

Wu, Zheng
Molecular Dissection of Neural Circuits Underlying Parental Behavior in Mice
Advisor: Catherine Dulac

2012

Brady, Daniel
Mechanisms of Cross-Modal Refinement by Visual Experience
Advisor: Takao Hensch

De la Huerta, Irina
Expression and Role of Cadherins in the Mammalian Visual System
Advisor: Joshua Sanes

Ganesh, Vijay
Identification and Characterization of Genes Essential for Human Brain Development
Advisor: Christopher Walsh

Gelfand, Maria
Characterization of the in vivo function of Neuropilin1 during development
Advisor: Chenghua Gu

Han, Juliette
The Role of TSC in Oligodendrocyte Differentiation and Myelination
Advisor: Mustafa Sahin

Hong, Soyon
Probing the in vivo economy of amyloid beta-protein during the development of Alzheimer’s disease-type pathology
Advisor: Dennis Selkoe

Huang, Kuo-Hua
Control of Turning Behaviors by Spinal Projection Neurons in the Larval Zebrafish
Advisor: Florian Engert

Lehnert, Brendan
The role of TRP channels in auditory transduction and amplification in Drosophila
Advisor: Rachel Wilson

Min, Lia
Experience-Dependent Loss of Cross-Modal Plasticity in Mouse Visual Cortex
Advisor: Michela Fagiolini

Ni, Amy
Visual Attention and the Role of Normalization
Advisor: John Maunsell

Ruff, Douglas
Neuronal Tuning and its Role in Attention
Advisor: Richard Born

Smolyanskaya, Alexandra
Dynamics of cortical decision circuits during changes in the fidelity of sensory representations
Advisor: Richard Born

Soskis, Michael
A chemical-genetic study of EphB receptor tyrosine kinase signaling in the developing nervous system
Advisor: Michael Greenberg

Wang, Alice
Neural substrates of choosing actions and motivational drive, a role for the striatum
Advisor: Naoshige Uchida

Wang, Oulu
Glucocorticoids regulate kisspeptin neurons during stress and contribute to infertility and obesity in leptin-deficient mice
Advisor: Joseph Majzoub

Zhou, Yi
Olfactory Transduction and Taste Processing in Drosophila
Advisor: Rachel Wilson

2011

Bock, Dravida
Network anatomy and in vivo physiology from a group of visual cortical neurons
Advisor: R. Clay Reid

Carter, Brett
Sodium Current during and between Action Potentials of GABAergic and Glutamatergic Neurons
Advisor: Bruce Bean

Cury, Kevin
The Role of Spike Timing in Odor Coding During Sniffing
Advisor: Naoshige Uchida

Dakin, Kelly
Novel Biological Functions of Hemoglobin in the Brain
Advisor: Bruce Yankner

Fitzgerald, Jamie
Generalized associative representations in parietal cortex
Advisor: John Assad

Kaczmarek, Jan
Novel activation mechanisms of TRPC5 reveal its participation in neuronal growth cone collapse
Advisor: David Clapham

Kerlin, Aaron
Response properties of inhibitory neuron subtypes in mouse visual cortex
Advisor: R. Clay Reid

Litterman, Nadia
A Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning
Advisor: Azad Bonni

Myoga, Michael
Calcium-Dependent Synaptic Plasticity in the Cerebellum
Advisor: Wade Regehr

2010

Abdel-Azim, Eiman
Molecular Controls over Neocortical Neuronal Diversity and Oligodendrocyte Development
Advisor: Jeffrey Macklis

Appler, Jessica
The Molecular and Morphological Development of Spiral Ganglion Neurons
Advisor: Lisa Goodrich

Bilimoria, Parizad
Signaling Mechanisms Regulating Neuronal Morphogenesis in the Cerebellar Cortex
Advisor: Azad Bonni

Bortnick, Rachel
Genetic Dissection of the Dscam Pathway
Advisor: Dietmar Schmucker

Buchman, Joshua
Roles of centrosome proteins associated with primary microcephaly in mammalian corticogenesis
Advisor: Li-Huei Tsai

Courchesne-Schlink, Stephanie
Spatial Aspects of Neuronal Survival Signaling in Sensory Neurons
Advisor: Rosalind Segal

de la Torre Ubieta, Luis
Transcriptional Regulation of Neuronal Polarity
Advisor: Azad Bonni

Giessel, Andrew
Local, Non-linear Regulation of Synaptic Signals at Dendritic Spines of CA1 Pyramidal Cells
Advisor: Bernardo Sabatini

Hong, Youn-Young
Structure and Development of Retinal Ganglion Cells
Advisor: Joshua Sanes

Knoll, Allison
Role of Kappa Opioid Receptors in Fear and Anxiety-like Behaviors in Rats
Advisor: William Carlezon

Kurshan, Peri
The Role of Alpha2delta-3 in Calcium-Channel Localization, Synaptic Function and Bouton Formation
Advisor: Thomas Schwarz

Magnotti, Laura
Gap Junctions Between Astrocytes and Oligodendrocytes are Critical for Normal Glial Function
Advisor: David Paul

Neal, Jason
Insights into the role of Filamin A and ARFGEF2 genes in periventricular heterotopia formation
Advisor: Christopher Walsh

Sadacca, Leigh
Circadian Clocks in Behavior and Physiology
Advisor: Charles Weitz

Sturgill, James
Activity-dependent Regulation of Synapse Structure and Function: Roles of PSD-95 and the Metabolic Sensor, AMPK
Advisor: Bernardo Sabatini

Witt, Rochelle
Of Structure and Function: The Nature of the Sonic Hedgehog-Heparan Sulfate Proteoglycan Interaction
Advisor: Rosalind Segal

Yang, Yue
A Cdc20-APC Ubiquitin Signaling Pathway Regulates Presynaptic Differentiation
Advisor: Azad Bonni

2009

Abraira, Victoria
Molecular Mechanisms of Inner Ear Morphogenesis
Advisor: Lisa Goodrich

Christensen, Adam
The Role of TRP Channels in Mechanosensation
Advisor: David Corey

Flavell, Steven
Regulation of synapse development by the activity-regulated transcription factor MEF2
Advisor: Michael Greenberg

Ge, Xuecai
Functions of the Centrosome in Embryonic Neurogenesis
Advisor: Li-Huei Tsai

Gouwens, Nathan
Processing of Neural Signals in the Drosophila Olfactory System
Advisor: Rachel Wilson

Hong, Elizabeth
Functional Significance of Neuronal Activity-Dependent Transcriptional Regulation in the Nervous System
Advisor: Michael Greenberg

Hunter, John
Spatial Integration of Motion Signals in Macaque MT
Advisor: Richard Born

Kovtun, Misao
Characterization of an Importin beta11 Mutant at the Drosophila Neuromuscular Junction
Advisor: Thomas Schwarz

Libedinsky, Camilo
Neuronal Mechanisms of Visual Perception Role of Early Visual and Prefrontal Cortical Areas in Conscious Awareness
Advisor: Margaret Livingstone

Mosca, Timothy
Nuclear Import and Synapse to Nucleus Signalling at the Drosophila Neuromuscular Junction
Advisor: Thomas Schwarz

Ramdya, Pavan
Direction selectivity in the larval zebrafish optic tectum
Advisor: Florian Engert

Rappley, Irit
Selective Effects of Alpha-Synuclein on Membrane Phospholipids and Mitochondrial Function
Advisor: Dennis Selkoe

Tanner, Geoffrey
K(ATP) Channels, Metabolism, and Neuronal Excitability
Advisor: Gary Yellen

Tischfield, Max
Human eye movement disorders help identify molecular and genetic etiologies of novel neurological syndromes
Advisor: Elizabeth Engle

2008

Albeanu, Dinu
Multimodal Imaging of Sensory Inputs and Neuronal Coding in the Rodent Olfactory Bulb
Advisor: Venkatesh Murthy

Berg, James
Imaging Neuronal Metabolism
Advisor: Gary Yellen

Ch'ng, Yeang
Functional Imaging of Cellular and Vascular Activity in Visual Cortex
Advisor: R. Clay Reid

Colodner, Kenneth
Using Drosophila to investigate the glial contribution to neurodegenerative disorders
Advisor: Mel Feany

Do, Michael
Generation and Regulation of Pacemaking in Subthalamic Neurons
Advisor: Bruce Bean

Haushofer, Johannes
Cortical Object Representations
Advisor: Margaret Livingstone

Hyde, Rhonda
Genetic Analysis of Protein Kinase C and MAPK in C. elegans mechanosensation
Advisor: Anne Hart

Koundakjian, Edmund
An analysis of the development of the cochlear-vestibular ganglion
Advisor: Lisa Goodrich

Lu, Alice
Potential Roles for Ubiquilin 1 in Alzheimer's Disease Pathogenesis
Advisor: Rudolph Tanzi

Lu, Ju
Connectomic Studies of the Mammalian Neuromuscular System
Advisor: Jeff Lichtman

Olsen, Shawn
Synaptic and Circuit Mechanisms of Odor Processing in Drosophila
Advisor: Rachel Wilson

Ponce, Carlos
Integrating Visual Information Through Parallel Pathways
Advisor: Richard Born

Shankar, Ganesh
Soluble Abeta Oligomers and Synaptic Dysfunction in Alzheimer's Disease
Advisor: Dennis Selkoe

Simon, David
microRNA Regulation of Synapse Function in C.elegans
Advisor: Joshua Kaplan

2007

Bikoff, Jay
Molecular mechanisms regulating cortical development: From neurons to synapses
Advisor: Michael Greenberg

Chung, Eunju
Axonal Transport of Synaptic Components and Synaptogenesis in Drosophila
Advisor: Thomas Schwarz

Gopal, Raj
Regulation of DNA Double-Strand Break Repair by Parkin
Advisor: Bruce Yankner

Harrar, Dana
An RNA Interference Screen Identifies New Molecules Required for Mammalian Synapse Development
Advisor: Michael Greenberg

Hass, Matthew
Identification of Novel Roles of the Amyloid Precursor Protein in Signal Transduction
Advisor: Bruce Yankner

Hemming, Matthew
Regulation of Amyloid b-Protein Levels by Proteolytic Degradation and its Implications for Alzheimer's disease
Advisor: Dennis Selkoe

Herrington, Todd
Attentional Shifts in Parietal Cortex and Behavior
Advisor: John Assad

Hooks, Bryan
Functional Development of the Retinogeniculate Synapse
Advisor: Chinfei Chen

Hughes, Michael
A Genetic and Biochemical Analysis of Dscam Signaling in Dendrite Morphogenesis
Advisor: Dietmar Schmucker

Kontopoulos, Eirene
Mechanisms of a-synuclein Neurotoxicity in Parkinson's Disease
Advisor: Mel Feany

Safo, Patrick
THE ROLE OF ENDOCANNABINOIDS IN SYNAPTIC PLASTICITY AT THE GRANULE CELL TO PURKINJE CELL SYNAPSE
Advisor: Wade Regehr

Soler-Llavina, Gilberto
Compartmentalization and modulation of synaptic signaling in dendrites and spines
Advisor: Bernardo Sabatini

Vijayan, Sujith
Characterization of Activity in the Primary Somatosensory Cortex During Active Behavior and Sleep
Advisor: Emery Brown

2006

Ardayfio, Paul
Behavioral Investigation of Cognitive Function in Mouse Models of Neurological and Psychiatric Disorders
Advisor: Kwang-Soo Kim

Bloodgood, Brenda
Biochemical Compartmentalization and Synaptic Signaling in Spines
Advisor: Bernardo Sabatini

Choi, Yoojin
Mitogenic Niches in the Developing Cerebellum
Advisor: Rosalind Segal

de Vries, Saskia
Modulation of Retinal Responses by Single Amacrine Cells
Advisor: Markus Meister

Dekker, John
Molecular Analysis of Gating in Voltage-Dependent Ion Channels
Advisor: Gary Yellen

Dietz, Shelby
Plasticity and Development of the Mitral-Granule Reciprocal Synapse in the Mammalian Olfactory Bulb
Advisor: Venkatesh Murthy

Edson, Eleanore
Contributions of Glutamate Transporters and Metabotropic Glutamate Receptors to Synaptic Transmission Over Development at the Retinogeniculate Synapse
Advisor: Chinfei Chen

Fantana, Antoniu
Odor Processing in the Olfactory Bulb: Structure of Mitral Cell Receptive Fields
Advisor: Markus Meister

Glater, Elizabeth
The Mechanism for Axonal Transport of Mitochondria in Drosophila
Advisor: Thomas Schwarz

Goddard, Carson
MHC Class I and the Homeostatic Regulation of CNS Synapses
Advisor: Carla Shatz

Gooley, Joshua
Entrainment of the Circadian Timing System by Light and Food
Advisor: Clifford Saper

Griffin, Robert
Gene Expression Associated with Neuropathic Pain
Advisor: Clifford Woolf

Hafler, Brian
Transcriptional Regulation of Olig2 in Motor Neuron Development
Advisor: David Rowitch

Hartman, Kenichi
Regulation of Neuronal Morphology and Synaptic Development by Activity
Advisor: Venkatesh Murthy

Jackson, Alexander
Subthreshold Currents Underlying the Spontaneous Firing of Hypothalamic Pacemaker Neurons
Advisor: Bruce Bean

Khurana, Vikram
Mitogenic signaling and cell-cycle activation mediate neurodegeneration in Drosophila
Advisor: Mel Feany

Koprivica, Vuk
Mechanisms of Myelin Regeneration Inhibition
Advisor: Zhigang He

Lehtinen, Maria
Survival and Death Signaling Pathways: From Single Cells to Organisms
Advisor: Azad Bonni

Marcus, Jacob
Orexin Receptors and the Central Autonomic System
Advisor: Joel Elmquist

McKellar, Claire
A Program of New Gene Expression Induced by Synaptogenesis
Advisor: Carla Shatz

Molyneaux, Bradley
Molecular Development of Corticospinal Motor Neurons
Advisor: Jeffrey Macklis

Patten, Brooke
Molecular Mechanisms of Radial Glia Formation in the Developing Cerebellum
Advisor: Gabriel Corfas

Samuels, Benjamin
Physiological Functions of Cdk5 in the Nervous System
Advisor: Li-Huei Tsai

Yiu, Glenn
Signaling Mechanisms Limiting Axon Regeneration in the Adult Central Nervous System
Advisor: Zhigang He

2005

Basu, Alo
Characterization of an Amine-Modulated Stress Neuropeptide System in Homarus americanus
Advisor: Edward Kravitz

Emerson, Mark
A Misexpression Genetic Screen in Drosophila Identifies Candidate Axon Guidance Factors with Differential Expression
Advisor: David Van Vactor

Harpavat, Sanjiv
Roles of Thyroid Hormone in Chick Retinal Development
Advisor: Constance Cepko

Kraves, Sebastián
Molecular Analyses of the Circadian Control of Locomotor Activity in Mammals
Advisor: Charles Weitz

Maimon, Gaby
Cortex, Vision and Action
Advisor: John Assad

Roberson, Christov
G Protein Regulation of Inwardly Rectifying Potassium Channels
Advisor: David Clapham

Shen, Jun
Using Forward and Reverse Genetics to Study Genes That Control the Size of the Brain
Advisor: Christopher Walsh

Tran, Hien
A Role for Forkheads in the Response to Stress
Advisor: Michael Greenberg

Wang, Duo
Negative regulation of RNA interference in Caenorhabditis elegans
Advisor: Gary Ruvkun

Whalen, Brian
Early Events in Alzheimer's Disease: An Examination of Amyloid-Beta Protofibril Biology
Advisor: Dennis Selkoe

Zakhary, Lisa
Anatomical and Functional Analysis of MicroRNAs in Mammalian Olfactory Neurogenesis
Advisor: Catherine Dulac

2004

Altevogt, Bruce
Analysis of connexins in myelination
Advisor: David Paul

Bianchetta, Michael
Self-Association of the Muscle-Specific Receptor Tyrosine Kinase MuSK
Advisor: Jonathan Cohen

Blair, Nathaniel
Contributions of Voltage-gated Sodium, Calcium and Potassium Currents to the Excitability of Nociceptive Sensory Neurons
Advisor: Bruce Bean

Brittis, Perry
RNA Based Mechanisms for Locally Regulating Axon Guidance Decisions
Advisor: John Flanagan

Chae, Teresa
Genetic and Phenotypic Analysis of the hyh Mouse Mutant
Advisor: Christopher Walsh

Chyung, Jay
Cell Surface Events in the Amyloidogenic Processing of the Amyloid Precursor Protein
Advisor: Dennis Selkoe

Currier, Sophie
Genetics of Walker-Warburg Syndrome A Disorder of Brain, Muscle and Eye Development
Advisor: Christopher Walsh

Deuel, Thomas
Doublecortin and the Doublecortin-like Kinase in CNS Development and Plasticity
Advisor: Christopher Walsh

Foster, Kelly
Mechanisms and Functional Consequences of Short-Term Plasticity at Excitatory Synapses in the Cerebellum
Advisor: Wade Regehr

Greka, Anna
TRP Channels and the Cytoskeleton: Implications for Neuronal Growth and Cellular Motility
Advisor: David Clapham

Heerssen, Heather
Mechanisms of Trk Receptor Retrograde Transport and Signaling
Advisor: Rosalind Segal

Kimberly, William
Intramembrane Proteolysis and Signal Transduction: The g-Secretase Complex and its Connection to Alzheimer's Disease
Advisor: Dennis Selkoe

Ko, Jane
CDK5 in Neuronal Development and Potential Regulation of Kinesins
Advisor: Li-Huei Tsai

Konopka, Genevieve
Regulation of STAT3 Signaling in Astrocyte Transformation
Advisor: Azad Bonni

Sandoval, Gisela
Molecular Genetic Analysis of an Interaction between the Vesicular Acetylcholine Transporter and Synaptobrevin in Caenorhabditis Elegans
Advisor: Gary Ruvkun

Sauvageot, Claire
Genomic Analysis of Fate Choice in Cortical Progenitor Cells
Advisor: Charles Stiles

St. Pierre, Susan
Neuronal specification in Drosophila: the roles of rotund and squeeze, two related zinc finger genes
Advisor: Stefan Thor

Webster, Sarah
Structures and mechanisms of gating in Shaker voltage-dependent potassium channels
Advisor: Gary Yellen

Yang, Fu-Chia
The Potential Role for the EGF Receptor System in the Circadian Regulation of Locomotor Activity
Advisor: Charles Weitz

2003

Carter, Alexandre
Neurotrophin Modulation of Cerebellar Development and Synaptic Plasticity
Advisor: Rosalind Segal

Catapano, Lisa
Stage-Specific Control over Neocortical Callosal Projection Neuron Survival and Differentiation
Advisor: Jeffrey Macklis

Chang, Dennis
Circadian Clock Molecules of a Lepidopteran Insect, Antheraea pernyi, and Comparisons with the Fruit Fly, Drosophila melanogaster
Advisor:

Chou, Thomas
Regulation of Sleep-Wake Timing: Circadian Rhythms and Bistability of Sleep-Wake States
Advisor: Clifford Saper

Griffin, Edmund
Light, Cryptochrome, and Circadian Clocks
Advisor: Charles Weitz

Moran, Magdalene
TLF is a Functional Regulator or Transcription with Targets that are Distinct from the TATA-Box Binding Protein (TBP)
Advisor: David Clapham

Nadal-Vicens, Mireya
Signaling Mechanisns that Govern the Switch from Neuronal to Astrocyte Differentiation in Neocortical Progenitors
Advisor: Michael Greenberg

Nigh, Elizabeth
The Control of Protein Expression During Adaptive Neuronal Responses
Advisor: Michael Greenberg

Olveczky, Bence
Retinal Processing of Natural Motion
Advisor: Markus Meister

Rodriguez, Carolyn
Innovating Genetic Technology to Map the Origin of the Precerebellar System
Advisor: Susan Dymecki

Taddese, Abraha
Electrophysiology of Spontaneously Active Tuberomammillary Nucleus Neurons
Advisor: Bruce Bean

Tavazoie, Sohail
The Development of Neural Connections from Retina to Thalamus: Maturation and Plasticity of Receptive Fields
Advisor: R. Clay Reid

Trinidad, Jonathan
The Localization and Function of Neuregulin and the ErbB Receptors at the Neuromuscular Junction
Advisor: Jonathan Cohen

Wang, Kevin
Signaling Mechanisms Underlying Inhibition of Axonal Regeneration by CNS Myelin
Advisor: Zhigang He

Zhang, Ying
Where is it? Deriving Stimulus Location from the Responses of Visual Neurons
Advisor: R. Clay Reid

2002

Carter, Adam
Synaptic Transmission at Cerebellar Stellate Cells
Advisor: Wade Regehr

Deans, Michael
Connexin 36 Localization and Function within the Rod Pathways of the Mouse Retina
Advisor: David Paul

Gaus, Stephanie
Neuroanatomic Substrates for Circadian Control of Sleep
Advisor: Clifford Saper

Lin, Jerry
I. Characterization of an NMDA Receptor- Associated Complex Centered around NR1 II. The Role of AMPA Receptor Trafficking in Synaptic Plasticity
Advisor: Morgan Sheng

Reppas, John
Saccadic Eye Movements and Early Vision
Advisor: R. Clay Reid

Seth, Kim
A Molecular Genetic Investigation of the Role of RE-1/REST in the Transcriptional Regulation of the Corticotropin-Releasing Hormone (CRH) Gene
Advisor: Joseph Majzoub

Tsao, Doris
Stereopsis
Advisor: Margaret Livingstone

Vedantham, Vasanth
Moving Parts of Voltage-Gated Sodium Channels
Advisor: Stephen Cannon

2001

Atluri, Pradeep
The Role of Presynaptic Calcium in Short-Term Synaptic Plasticity
Advisor: Wade Regehr

Awobuluyi, Marc
Translational Control of N-Methyl-D-Aspartate Subunit 1 (NMDAR1) Expression
Advisor:

Borghesani, Paul
Neuronal Migration in Development and Degeneration
Advisor: Rosalind Segal

Brown, Solange
Local Circuits in the Retina: Spatial Sensitivity, Contrast Adaptation and Direction Selectivity of Retinal Ganglion Cells
Advisor: Richard Masland

Chao, Steven
GAP-43: Regulation and Function
Advisor: Larry Benowitz

Christie, Richard
In vivo Imaging of Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
Advisor: Bradley Hyman

Chua, Katrin
Remodeling of the Spliceosome for Catalysis of Exon Ligation
Advisor: Robin Reed

Conway, Bevil
Mechanisms of Color and Motion in Monkey Visual Cortex
Advisor: Margaret Livingstone

Garcia, Jesus
Activation and Regulation of Mechanosensitive Ion Channels
Advisor: David Corey

Kang, Shin Jung
A Dual Role of Capase-11 under Pathological and Physiological Conditions
Advisor: Junying Yuan

Kreitzer, Anatol
Activity-Dependent Modulation of Synaptic Strength in the Central Nervous System
Advisor: Wade Regehr

Magavi, Sanjay
Induction of Neurogenesis in the Neocortex of Adult Mice and Assessment of the Functional Integration of Adult-born Neurons
Advisor: Jeffrey Macklis

Mason, Heather
Cellular and Molecular Mechanisms of Neuronal Chain Migration
Advisor: Gabriel Corfas

Morrill, James
Biophysical Properties of the Skeletal Muscle L-Type Calcium Channel in Health and Disease
Advisor: Stephen Cannon

Orlando, Lianna
Metabotropic Glutamate Receptors in Rat Striatum: Interactions with NMDA Receptors
Advisor:

Scharf, Jeremiah
Comparative Genomic Analysis of the Spinal Muscular Atrophy (SMA) Region in Mouse and Man: Applications for Understanding Disease Pathogenesis
Advisor: Louis Kunkel

2000

Aghi, Manish
Improving the Efficacy of Chemosensitizing Brain Tumor Gene Therapies
Advisor: Xandra Breakefield

Choi, Yun-Beom
Molecular Analysis of Modulatory Sites on the NMDA Receptor: Redox, Zn2+, and Nitric Oxide-Related Species
Advisor:

Day, Michelle
The Effects of Serotonin 5-HT2A Agonists and Antagonists on High-Voltage-Activated Calcium Currents in Prefrontal Pyramidal Neurons
Advisor:

Dittman, Jeremy
Presynaptic Modulation of Transmitter Release in the Central Nervous System
Advisor: Wade Regehr

Horowitz, Lisa
Connectivity in the Mouse Olfactory System
Advisor: Linda Buck

Malick, Amy
On Trigeminohypothalamic Pain Pathways and How they Contribute to Anorexic Behavior
Advisor: Rami Burstein

Nadeau, Philip
An Investigation of the Role of Apolipoproteins, Lipoproteins and the Presenilin Proteins in Amyloid Beta Metabolism and Alzheimer's Disease
Advisor: Bruce Yankner

Naisbitt, Scott
The Molecular Organization of the Postsynaptic Density by GKAP and Shank
Advisor: Morgan Sheng

Ware, Marcus
Cellular and Molecular Events in the Development of the Cerebral Cortex
Advisor: Christopher Walsh

1999

Allwardt, Brenda
Ultrastructural Analysis of Photoreceptors in Wildtype and Mutant Zebrafish Larvae
Advisor: John Dowling

Barnes-Weninger, Stacie
Role of Corticotropin-Releasing Hormone (CRH) and CRH-Like Molecules in Stress-Induced Behavior
Advisor: Joseph Majzoub

Das, Saumya
Identification and Characterization of a Novel N-Methyl-D-Aspartate Receptor Subunit NR3A
Advisor: Nobuki Nakanishi

Gonzalez, Jorge Luis
Cellular and Biochemical Analysis of Mutations That Affect Cerebral Cortical Development
Advisor: Christopher Walsh

Green, Donnella
Functional Consequences of Sodium Channel Mutations in Human Neuromuscular Disease and a Novel Mechanism for Acetazolamide Therapy
Advisor: Stephen Cannon

Pratt, Megan
Mapping Noncompetitive Antagonist Binding Sites in the Nicotinic Acetylcholine Receptor
Advisor: Jonathan Cohen

Rieff, Heather
The Role of Neuregulin and erbB Receptors in Cerebellar Development
Advisor: Gabriel Corfas

Sabatini, Bernardo
Calcium Control of Neurotransmitter Release at a Cerebellar Synapse
Advisor: Wade Regehr

Senatus, Patrick
Electrophysiological and Cytochemical Properties of Rat Neostriatal Neurons in Microculture
Advisor: David Potter

Sincich, Lawrence
Local Circuits in Primary Visual Cortex
Advisor:

Smith, Paula
Voltage-dependent Gating of HERG Potassium Channels
Advisor: Gary Yellen

Van Koughnet, Kelly
Proenkephalin Transgene Regulation in the Paraventricular Nucleus of the Hypothalamus by Lipopolysaccharide and Interleukin-1b: a Model for the Study of Neuro-immune Communication
Advisor:

Watson, Fiona
Retrograde Signaling by Neurotrophins
Advisor: Rosalind Segal

Zeitzer, Jamie
Physiology and Anatomy of Human Circadian Photoreception and Melatonin Regulation
Advisor: Charles Czeisler

Zylka, Mark
Characterization of a Mammalian Circadian Feedback Loop
Advisor:

1998

Aggarwal, Sanjay
Analysis of the Voltage Sensor in a Voltage-Activated Potassium Channel
Advisor:

Belliveau, Michael
Intrinsic and Extrinsic Regulation of Cell Fate Choices in the Vertebrate Neural Retina
Advisor: Constance Cepko

Berke, Joshua
A Complex Program of Dopamine-Induced Gene Expression Identified Using Differential-Display PCR: Discovery of a Novel Inducible Cyclin
Advisor:

Genova, Lisa
Amphetamine-Induced Adaptations in Striatal Neurons: Roles of Serotonin and Conditioned Stimuli
Advisor:

Jenner, Annette
The Connectivity of Ectopic Neurons in the Neocortex and their Effects on Neuronal Size in the Thalamus: Implications for Developmental Dyslexia
Advisor:

Jordan, Thomas
Network Dynamics and their Neuromodulation: Dopaminergic Effects on Retinal Receptive Fields
Advisor: John Dowling

Niethammer, Martin
Organization of an NMDA Receptor-Associated Complex via the PDZ Domains of PSD-95
Advisor: Morgan Sheng

Schwartz, Phillip
Neurotrophins in the Regulation of Cerebellar Development
Advisor: Rosalind Segal

Sholas, Maurice G.
Changes in Primary Somatosensory Cortex Processing of Nociceptive Information Induced by Inflammation
Advisor:

Tramo, Mark
Neural Representations of Acoustic Information in Relation to Music and Voice Perception
Advisor:

West, Anne Elizabeth
Protein Targeting in Neurons
Advisor: Kathleen Buckley

1997

Bruce, Ashley
Characterization of an orthodenticle Homolog in the Leech and Investigation of Ectopic Gene Expression Techniques
Advisor:

Krauss, Raul
Studies of Nicotinic Acetylcholine Receptor Gene Expression in the Central Nervous System
Advisor:

Morris, Mary
Entrainment of the Mammalian Circadian Clock: Identification of Light-Induced Genes in the SCN
Advisor: Charles Weitz

Reid, Christopher Brian
Cell Lineage in Mammalian Cerebral Cortex
Advisor: Christopher Walsh

Ressler, Kerry
Odorant Receptor Organization and Information Coding in the Mouse Olfactory System
Advisor: Linda Buck

Sheen, Volney
Transplantation Strategies for Reconstruction of Complex Neocortical Circuitry
Advisor: Jeffrey Macklis

Sodickson, Deborah Lynn
Control of Inwardly Rectifying Potassium Channels and Voltage-Dependent Calcium Channels by G-Protein Coupled Tansmitter Receptors in Hippocampal Neurons
Advisor: Bruce Bean

Sorra, Karin Elena
Synapse Structure, Function and Plasticity in Hippocampal Area CA1
Advisor:

Tolentino, Paul
Transcriptional and Post-Transcriptional Regulation of VIP mRNA Expression
Advisor: Lydia Villa-Komaroff

Watson, Deborah
Effects of the HCHWA-D Mutation on bAPP Processing, Heterogeneity of Ab Deposits, and Heparin/HSPG Binding: Implications for Alzheimer's Disease
Advisor: Dennis Selkoe

Weiger, Wendy
Serotonergic Neurons in the Lobster: Excitatory and Inhibitory Inputs
Advisor: Edward Kravitz

Welsh, David
Circadian Clock Neurons in Culture
Advisor:

Wietasch, Kristina
Regulation of Neuronal Nicotinic Acetylcholine Receptors in the Interpeduncular Nucleus
Advisor:

1996

Ahn, Andrew
The Membrane Cytoskeleton in Muscular Dystrophy
Advisor: Louis Kunkel

Bonni, Azad
Neurotrophic Factor Regulation of Immediate Early Gene Expression
Advisor: Michael Greenberg

Cole, Rebecca Leah
Neurotransmitter Regulation of CRE- and AP-1-Mediated Gene Expression in Rat Striatum
Advisor:

Jackson, Paul
VSOAC: A Volume Sensitive Anion Channel with a Novel Function.
Advisor: Larry Benowitz

Knowles, Roger
Translocation of RNA Granules in Living Neurons
Advisor: Kenneth Kosik

Macknik, Stephen L.
The Physiology and Perception of Visibility and Visual Masking
Advisor: Margaret Livingstone

Overly, Caroline Cannon
Organelle Motility and Endocytic Pathways in Cultured Neurons
Advisor: Peter Hollenbeck

Peters, Bruce Nathan
Responses to Light of Starburst Amacrine Cells in the Retina of the Rabbit
Advisor: Richard Masland

Roca, Alfred Luis
The Mouse Mel1a Melatonin Receptor Gene
Advisor:

1995

Chang, Belinda
Opsin Phylogeny and Evolution
Advisor:

Chicurel, Marina
RNA Localization and RNA-Cytoskeletal Interactions in Neurons
Advisor: Huntington Potter

Fulwiler, Carl
Genetic Analysis of Retinal Development in Zebrafish
Advisor:

Gillette, Michael
Gamma-Aminobutyric Acid- and Glycine-Activated Currents and their Modulation in the Rod Bipolar Cell of the Rabbit Retina
Advisor:

Hung, Albert
Regulation of Expression and Processing of the b-Amyloid Precursor Protein of Alzheimer's Disease
Advisor: Dennis Selkoe

Johnson, Mark
Electrophysiological and Cytochemical Properties of Rat Mesopontine Serotonergic Neurons in Culture
Advisor: David Potter

Martinez, Camilo
Molecular Regulation of Corticotropin Releasing Hormone Gene Expression by the Protein Kinase A Pathway and Glucocorticoids
Advisor: Joseph Majzoub

Navia, Bradford
Molecular Analysis of the Region Surrounding the X-Linked Retinitis Pigmentosa (RP3) Locus in Xp21.1
Advisor:

Shepherd, Gordon
Components of Adaptation in Saccular Hair Cells of the Bullfrog, Rana catesbeiana
Advisor: David Corey

Sydor, Anne
The Role of Cytoskeletal Proteins Talin and Vinculin in Neuronal Growth Cone Motility.
Advisor: Daniel Jay

Valentine, Doreen
Spatial Perception and Sensorimotor Integration: The Role of the Superior Colliculus in the Echolocating Bat, Eptesicus fuscus
Advisor:

1994

Chung, Richard
p53, A Bifunctional Transcriptional Regulatory Protein Inactivated in Human Astrocytic Tumors
Advisor:

Finch, Elizabeth
Inositol Trisphosphate-Mediated Calcium Release: Kinetics and Regulation by IP3, Calcium, and ATP
Advisor:

Lewis, Susan
Cytokine Regulation of Neuronal Gene Expression in Sympathetic Neurons and a Neuroblastoma Cell Line
Advisor:

Marsh-Armstrong, Nicholas
Retinoic Acid and the Patterning of the Zebrafish Retina and Trunk
Advisor:

Potrebic, Sonja
The Role of Serotonin in the Modulation of Nociception by the Rostral Ventromedial Medulla of the Rat
Advisor:

1993

Cardozo, David
Electrophysiology of Dissociated Midbrain Dopamine Neurons
Advisor: David Potter

Feany, Mel
Molecular Analyses of Synaptic Vesicle Proteins/Genetic and Molecular Studies of Drosophila Learning Mutants
Advisor: Kathleen Buckley

Heginbotham, Lise
Identification and Molecular Characterization of a Potassium Channel Pore
Advisor:

Kobierski, Linda
Proenkephalin Gene Expression: Mechanisms of cAMP Regulation
Advisor: Michael Comb

Nardone, Julie
Site-Directed Mutagenesis of a B2 Bradykinin Receptor
Advisor: David Potter

Nirenberg, Sheila
Targeted Ablation of Diverse Cell Types in the Nervous System: a Method for Blocking Cell-Cell Interactions in Vivo
Advisor: Constance Cepko

Swartz, Kenton
Regulation of Neuronal Ca Channels by Neurotransmitters, G Proteins and Kinase C
Advisor: Bruce Bean

Thompson, Margaret
Regulation of c-fos Transcription by Calcium
Advisor: David Potter

Student Body

2013-2014 Enrollment

 

Total Enrollment: 116

Average Size of Incoming Class: 19

Average Time to Degree:

Ph.D. Students: 5.86 years

M.D./Ph.D. Students: 4.86 years

 

Women: 51 (44%)

Men: 65 (56%)

 

Underrepresented Minority: 7 (6%)

 

Domestic: 98 (84%)

International: 18 (16%)

 

PhD: 100 (86%)

MD-PhD: 16 (14%)

 


© 2014 by the President and Fellows of Harvard College