PiN Faculty Members Listed by Research Area

Cell Biology of Neurons & Glia | Development & Plasticity | Gene Expression | Neuropathology & Disease | Neuropharmacology & Neurochemistry | Receptors & Ion Channels | Synapse Function & Plasticity | Systems & Integrative Neuroscience




Cell Biology of Neurons & Glia

Matthew Anderson

Molecular and Circuit Defects Underlying Human Genetic Forms of Autism and Epilepsy
 

Paola Arlotta

Investigation of the molecular mechanisms governing development and reprogramming of neuronal subtypes in the mammalian cerebral cortex.
 

Brian Bacskai

Optical imaging in animal models of Alzheimer’s disease
 

Sabina Berretta

Extracellular matrix/neuron/glia interactions in the pathophysiology of schizophrenia and bipolar disorder.
 

Xandra Breakefield

Genetic etiology, role of exosomes and gene therapy for neurologic diseases
 

William Carlezon

How experience affects the brain and behavior
 

Elena Chartoff

Molecular mechanisms and neural circuits of motivated behavior related to addiction in rodent models
 

Isaac Chiu

Neuro-immune Mechanisms of Pain and Inflammation
 

Adam Cohen

Optical electrophysiology and neuronal biophysics
 

Sandeep Robert Datta

Functional and Behavioral Interrogation of Neural Circuits in the Mammalian Olfactory System
 

Ulf Dettmer

Modeling protein dyshomeostasis in Parkinson's disease and exploring strategies to correct it
 

Michael Do

A Biophysical Approach to System Function
 

Min Dong

Molecular mechanisms of synaptic transmission and botulinum neurotoxins
 

Susan Dymecki

Specialization in the Serotonin System Shapes Behavior and Regulates Homeostasis
 

Elizabeth Engle

Cranial axon growth and guidance
 

Mel Feany

Genetics of neurodegenerative disease
 

Fishell, Gord

The genetics, biochemistry and physiology of forebrain inhibition.
 

John Flanagan

Cell-cell signaling in development and regeneration of axonal connections
 

Rachelle Gaudet

Structural biology of signaling and transport across cellular membranes
 

David Ginty

The functional organization of neural circuits underlying the perception of touch
 

Lisa Goodrich

Development and organization of neural circuits underlying hearing and vision
 

Jesse Gray

Genomic mechanisms of neuronal activity-regulated transcription and its regulation of neuronal plasticity
 

Chenghua Gu

Mechanisms of neuro-vascular interactions in the central nervous system
 

Penny Hallett

Mechanisms of neurodegeneration in Parkinson’s disease, and testing neuroprotective and neurorestorative therapies
 

Zhigang He

Cellular and Molecular Mechanisms in Axon Guidance and Regeneration
 

Maxwell Heiman

How neurons and glia pick their partners, using C. elegans as a model
 

Bradley Hyman

Neurobiology of neurodegenerative diseases using human, mouse, and culture systems, and employing advanced microscopy methods
 

Ole Isacson

Neuron and glia disease mechanisms of age-dependent degeneration and repair
 

Pascal Kaeser

Architecture and plasticity of neurotransmitter release sites
 

Joshua Kaplan

Genetic analysis of synaptic transmission
 

Vikram Khurana

Genome and Proteome-Scale Dissection of Neurodegenerative Proteinopathy in Human Stem Cell Models
 

Kwang-Soo Kim

Molecular and stem cell research of the dopamine system to study and treat human diseases
 

Matt LaVoie

The role of proteostasis deficits and mitochondrial dysfunction in neurodegenerative diseases
 

Maria Lehtinen

Mechanisms of brain development, with a focus on the choroid plexus-cerebrospinal fluid system
 

Stephen Liberles

Internal and External Sensory Systems
 

Jeff Lichtman

Studies of synaptic circuitry and their rearrangements
 

Jonathan Lipton

Circadian rhythms and translational control in neurological diseases of the developing brain
 

Kun Ping Lu

Molecular mechanisms and treatments of Alzheimer’s disease and cancer
 

Jeffrey Macklis

Mammalian cerebral cortex– fundamental molecular development, neuronal diversity, development-maintenance of specific circuitry, degenerative diseases, regeneration
 

Richard Masland

Functional Organization of the Retina
 

Sean Megason

Development of the spinal cord and inner ear using in toto imaging in zebrafish
 

Venkatesh Murthy

Algorithms and Neural Circuits in Olfaction
 

Lauren Orefice

Development, function and dysfunction of the somatosensory system
 

David Paul

Intercellular Communication
 

Matthew Pecot

Molecular mechanisms underlying the assembly of neural circuits.
 

Paul Rosenberg

glutamate transporters, cell death, sleep/wake regulation
 

Bernardo Sabatini

Cellular and synaptic mechanisms of learning and development
 

Mustafa Sahin

Cellular Mechanisms of Neurodevelopmental Disorders and Epilepsy
 

Joshua Sanes

Assembly of neural circuits in the mammalian visual system
 

Thomas Schwarz

Genetics of Neuronal Cell Biology
 

Rosalind Segal

Molecular mechanisms of Proliferation and Survival in Neural development
 

Dennis Selkoe

Molecular Mechanisms of Neurodegeneration in Alzheimer's and Parkinsons Diseases
 

Khalid Shah

Therapeutic and diagnostic stem cells for neurological disorders
 

Jie Shen

Mechanisms of neurodegeneration in Alzheimer’s and Parkinson's Diseases and development of novel therapies
 

Rudolph Tanzi

Genetic, molecular and biochemical studies of Alzheimer's disease from gene discovery to model systems to novel therapeutics
 

Brian Wainger

How abnormal physiology contributes to motor and sensory diseases.
 

Christopher Walsh

Development and disorders of the human cerebral cortex
 

Bruce Yankner

Molecular Genetics of Aging and Neurodegenerative Disorders
 

Gary Yellen

Neuronal metabolism and excitability; Fluorescent biosensor imaging; K-ATP channels and anti-epilepsy mechanisms
 

Junying Yuan

Mechanisms of Programmed Cell Death
 
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Development & Plasticity

Mark Andermann

Circuit approaches to understanding selective processing of motivationally salient sensory stimuli
 

Todd E. Anthony

Genetic dissection of neural circuits that control stress-induced behavioral states
 

Paola Arlotta

Investigation of the molecular mechanisms governing development and reprogramming of neuronal subtypes in the mammalian cerebral cortex.
 

Larry Benowitz

Axonal development and reorganization
 

William Carlezon

How experience affects the brain and behavior
 

Constance Cepko

Retinal development and degeneration, development of transsynaptic tracing viruses and nanobody reagents
 

Sandeep Robert Datta

Functional and Behavioral Interrogation of Neural Circuits in the Mammalian Olfactory System
 

Benjamin de Bivort

Characterizing the molecular, neural circuit and ecological underpinnings of behavioral diversity in fruit flies.
 

Michael Do

A Biophysical Approach to System Function
 

Susan Dymecki

Specialization in the Serotonin System Shapes Behavior and Regulates Homeostasis
 

Elizabeth Engle

Cranial axon growth and guidance
 

Fishell, Gord

The genetics, biochemistry and physiology of forebrain inhibition.
 

John Flanagan

Cell-cell signaling in development and regeneration of axonal connections
 

Nadine Gaab

Developmental cognitive neuroscience and pediatric neuroimaging with a special focus on language-based learning disabilities
 

David Ginty

The functional organization of neural circuits underlying the perception of touch
 

Lisa Goodrich

Development and organization of neural circuits underlying hearing and vision
 

Jesse Gray

Genomic mechanisms of neuronal activity-regulated transcription and its regulation of neuronal plasticity
 

Michael E. Greenberg

Signaling networks that regulate synapse development
 

Chenghua Gu

Mechanisms of neuro-vascular interactions in the central nervous system
 

Corey Harwell

Cellular and Molecular Mechanisms of Cortical Circuit Assembly
 

Zhigang He

Cellular and Molecular Mechanisms in Axon Guidance and Regeneration
 

Maxwell Heiman

How neurons and glia pick their partners, using C. elegans as a model
 

Jun Huh

Bacteria, immune cells and neurodevelopment
 

Pascal Kaeser

Architecture and plasticity of neurotransmitter release sites
 

Talia Konkle

Cognitive and neural architecture of high-level vision
 

Maria Lehtinen

Mechanisms of brain development, with a focus on the choroid plexus-cerebrospinal fluid system
 

Jeff Lichtman

Studies of synaptic circuitry and their rearrangements
 

Mary Loeken

Molecular regulation of neural tube development and neural tube defects in diabetic pregnancy
 

Qiufu Ma

The coding of pain versus itch
 

Jeffrey Macklis

Mammalian cerebral cortex– fundamental molecular development, neuronal diversity, development-maintenance of specific circuitry, degenerative diseases, regeneration
 

Sean Megason

Development of the spinal cord and inner ear using in toto imaging in zebrafish
 

Victor Navarro

Neuroendocrine control of reproductive function and metabolism
 

Charles Nelson

Developmental cognitive neuroscience, with particular interests in experience-dependent development
 

Lauren Orefice

Development, function and dysfunction of the somatosensory system
 

Matthew Pecot

Molecular mechanisms underlying the assembly of neural circuits.
 

Daniel Polley

Neuromodulation and plasticity in the auditory system
 

Amar Sahay

Hippocampal circuit and plasticity mechanisms underlying memory processing and regulation of mood
 

Joshua Sanes

Assembly of neural circuits in the mammalian visual system
 

Rosalind Segal

Molecular mechanisms of Proliferation and Survival in Neural development
 

Jie Shen

Mechanisms of neurodegeneration in Alzheimer’s and Parkinson's Diseases and development of novel therapies
 

Beth Stevens

Neuron-Glia Interactions During Development and Disease; Synapse Development and Plasticity; Neuro-Immune Interactions
 

Hisashi Umemori

Synapse formation and refinement in the mammalian brain
 

Christopher Walsh

Development and disorders of the human cerebral cortex
 
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Gene Expression

Mark Albers

Systems/Molecular Approaches to Elucidate Mechanisms that Cause Neurodegenerative Disease; Develop/Validate Novel Therapeutic Approaches
 

Mark Andermann

Circuit approaches to understanding selective processing of motivationally salient sensory stimuli
 

Matthew Anderson

Molecular and Circuit Defects Underlying Human Genetic Forms of Autism and Epilepsy
 

Larry Benowitz

Axonal development and reorganization
 

Sabina Berretta

Extracellular matrix/neuron/glia interactions in the pathophysiology of schizophrenia and bipolar disorder.
 

William Carlezon

How experience affects the brain and behavior
 

Constance Cepko

Retinal development and degeneration, development of transsynaptic tracing viruses and nanobody reagents
 

Elena Chartoff

Molecular mechanisms and neural circuits of motivated behavior related to addiction in rodent models
 

Michael Crickmore

Neurobiology of motivational states
 

Sandeep Robert Datta

Functional and Behavioral Interrogation of Neural Circuits in the Mammalian Olfactory System
 

Benjamin de Bivort

Characterizing the molecular, neural circuit and ecological underpinnings of behavioral diversity in fruit flies.
 

Susan Dymecki

Specialization in the Serotonin System Shapes Behavior and Regulates Homeostasis
 

Elizabeth Engle

Cranial axon growth and guidance
 

Fishell, Gord

The genetics, biochemistry and physiology of forebrain inhibition.
 

John Flanagan

Cell-cell signaling in development and regeneration of axonal connections
 

Lisa Goodrich

Development and organization of neural circuits underlying hearing and vision
 

Jesse Gray

Genomic mechanisms of neuronal activity-regulated transcription and its regulation of neuronal plasticity
 

Michael E. Greenberg

Signaling networks that regulate synapse development
 

Anna Greka

Ion channels and calcium signaling in health and disease
 

Maxwell Heiman

How neurons and glia pick their partners, using C. elegans as a model
 

Bradley Hyman

Neurobiology of neurodegenerative diseases using human, mouse, and culture systems, and employing advanced microscopy methods
 

Kwang-Soo Kim

Molecular and stem cell research of the dopamine system to study and treat human diseases
 

Gabriel Kreiman

Visual object recognition: computational models and neurophysiological mechanisms
 

Matt LaVoie

The role of proteostasis deficits and mitochondrial dysfunction in neurodegenerative diseases
 

Maria Lehtinen

Mechanisms of brain development, with a focus on the choroid plexus-cerebrospinal fluid system
 

Mary Loeken

Molecular regulation of neural tube development and neural tube defects in diabetic pregnancy
 

Bradford Lowell

Neural regulation of hunger, other homeostatic motivational drives, autonomic nervous system, and the neuroendocrine system
 

Qiufu Ma

The coding of pain versus itch
 

Jeffrey Macklis

Mammalian cerebral cortex– fundamental molecular development, neuronal diversity, development-maintenance of specific circuitry, degenerative diseases, regeneration
 

Evan Macosko

Genomic analyses of brain cell function and dysfunction
 

Joseph Majzoub

Hypothalamic role in mammalian endocrine and behavioral responses to stress
 

Lauren Orefice

Development, function and dysfunction of the somatosensory system
 

Matthew Pecot

Molecular mechanisms underlying the assembly of neural circuits.
 

Joshua Sanes

Assembly of neural circuits in the mammalian visual system
 

Clifford Saper

Neural circuitry for hypothalamic functions, including wake-sleep, thermoregulation, drinking, feeding, and stress responses
 

Clemens Scherzer

Translational Genomics of Parkinson’s Disease: Cause, Cures, Diagnostics
 

Khalid Shah

Therapeutic and diagnostic stem cells for neurological disorders
 

Jie Shen

Mechanisms of neurodegeneration in Alzheimer’s and Parkinson's Diseases and development of novel therapies
 

Rudolph Tanzi

Genetic, molecular and biochemical studies of Alzheimer's disease from gene discovery to model systems to novel therapeutics
 

Christopher Walsh

Development and disorders of the human cerebral cortex
 

Charles Weitz

Molecular Biology of Mammalian Circadian Clocks
 

Clifford Woolf

Adaptive and maladaptive plasticity in sensory and motor systems
 

Bruce Yankner

Molecular Genetics of Aging and Neurodegenerative Disorders
 
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Neuropathology & Disease

Mark Albers

Systems/Molecular Approaches to Elucidate Mechanisms that Cause Neurodegenerative Disease; Develop/Validate Novel Therapeutic Approaches
 

Mark Andermann

Circuit approaches to understanding selective processing of motivationally salient sensory stimuli
 

Matthew Anderson

Molecular and Circuit Defects Underlying Human Genetic Forms of Autism and Epilepsy
 

Todd E. Anthony

Genetic dissection of neural circuits that control stress-induced behavioral states
 

Paola Arlotta

Investigation of the molecular mechanisms governing development and reprogramming of neuronal subtypes in the mammalian cerebral cortex.
 

Brian Bacskai

Optical imaging in animal models of Alzheimer’s disease
 

Justin Baker

Deep phenotyping in mental illness
 

Sabina Berretta

Extracellular matrix/neuron/glia interactions in the pathophysiology of schizophrenia and bipolar disorder.
 

Vadim Bolshakov

Cellular and network-level mechanisms of innate and learned fear
 

Xandra Breakefield

Genetic etiology, role of exosomes and gene therapy for neurologic diseases
 

Joshua Buckholtz

brain Circuit Mechanisms for Decision-Making in Health and Disease
 

Randy Buckner

Human neuroscience explorations of large-scale brain circuit function and dysfunction
 

William Carlezon

How experience affects the brain and behavior
 

Constance Cepko

Retinal development and degeneration, development of transsynaptic tracing viruses and nanobody reagents
 

Elena Chartoff

Molecular mechanisms and neural circuits of motivated behavior related to addiction in rodent models
 

Isaac Chiu

Neuro-immune Mechanisms of Pain and Inflammation
 

Sandeep Robert Datta

Functional and Behavioral Interrogation of Neural Circuits in the Mammalian Olfactory System
 

Ulf Dettmer

Modeling protein dyshomeostasis in Parkinson's disease and exploring strategies to correct it
 

Elizabeth Engle

Cranial axon growth and guidance
 

Mel Feany

Genetics of neurodegenerative disease
 

John Flanagan

Cell-cell signaling in development and regeneration of axonal connections
 

Nadine Gaab

Developmental cognitive neuroscience and pediatric neuroimaging with a special focus on language-based learning disabilities
 

Gwenaelle Geleoc

Functional development of sensory hair cells of the mammalian inner ear and gene therapy of Usher Syndrome
 

Anna Greka

Ion channels and calcium signaling in health and disease
 

Chenghua Gu

Mechanisms of neuro-vascular interactions in the central nervous system
 

Penny Hallett

Mechanisms of neurodegeneration in Parkinson’s disease, and testing neuroprotective and neurorestorative therapies
 

Jeffrey Holt

Sensory Transduction in Hair Cells of the Mammalian Inner Ear
 

Jun Huh

Bacteria, immune cells and neurodevelopment
 

Bradley Hyman

Neurobiology of neurodegenerative diseases using human, mouse, and culture systems, and employing advanced microscopy methods
 

Artur Indzhykulian

Hair cell mechanotransduction, stereocilia bundle morphology and ultrastructure, AAV gene therapy for Usher Syndrome
 

Ole Isacson

Neuron and glia disease mechanisms of age-dependent degeneration and repair
 

Pascal Kaeser

Architecture and plasticity of neurotransmitter release sites
 

Rakesh Karmacharya

Neurobiology of disease: Chemical biology approaches in huan iPSC-derived neurons
 

Vikram Khurana

Genome and Proteome-Scale Dissection of Neurodegenerative Proteinopathy in Human Stem Cell Models
 

Matt LaVoie

The role of proteostasis deficits and mitochondrial dysfunction in neurodegenerative diseases
 

Maria Lehtinen

Mechanisms of brain development, with a focus on the choroid plexus-cerebrospinal fluid system
 

Jeff Lichtman

Studies of synaptic circuitry and their rearrangements
 

Jonathan Lipton

Circadian rhythms and translational control in neurological diseases of the developing brain
 

Mary Loeken

Molecular regulation of neural tube development and neural tube defects in diabetic pregnancy
 

Kun Ping Lu

Molecular mechanisms and treatments of Alzheimer’s disease and cancer
 

Jeffrey Macklis

Mammalian cerebral cortex– fundamental molecular development, neuronal diversity, development-maintenance of specific circuitry, degenerative diseases, regeneration
 

Evan Macosko

Genomic analyses of brain cell function and dysfunction
 

Lauren Orefice

Development, function and dysfunction of the somatosensory system
 

Diego Pizzagalli

Clinical neuroscience and neurobiology of depression
 

Paul Rosenberg

glutamate transporters, cell death, sleep/wake regulation
 

Mustafa Sahin

Cellular Mechanisms of Neurodevelopmental Disorders and Epilepsy
 

Joshua Sanes

Assembly of neural circuits in the mammalian visual system
 

Clifford Saper

Neural circuitry for hypothalamic functions, including wake-sleep, thermoregulation, drinking, feeding, and stress responses
 

Thomas Scammell

Neural circuitry of sleep and sleep disorders
 

Clemens Scherzer

Translational Genomics of Parkinson’s Disease: Cause, Cures, Diagnostics
 

Dennis Selkoe

Molecular Mechanisms of Neurodegeneration in Alzheimer's and Parkinsons Diseases
 

Khalid Shah

Therapeutic and diagnostic stem cells for neurological disorders
 

Jie Shen

Mechanisms of neurodegeneration in Alzheimer’s and Parkinson's Diseases and development of novel therapies
 

Kristina Simonyan

Neurobiology of Speech Motor Control
 

Stelios Smirnakis

Principles of Neural Circuit Function and Malfunction in Disease States such as Epilepsy, Autism and Stroke
 

Rudolph Tanzi

Genetic, molecular and biochemical studies of Alzheimer's disease from gene discovery to model systems to novel therapeutics
 

Christopher Walsh

Development and disorders of the human cerebral cortex
 

Ziv Williams

Human and primate social decision making, executive functioning and memory
 

Gary Yellen

Neuronal metabolism and excitability; Fluorescent biosensor imaging; K-ATP channels and anti-epilepsy mechanisms
 

Junying Yuan

Mechanisms of Programmed Cell Death
 
top

 

Neuropharmacology & Neurochemistry

Mark Albers

Systems/Molecular Approaches to Elucidate Mechanisms that Cause Neurodegenerative Disease; Develop/Validate Novel Therapeutic Approaches
 

Joshua Buckholtz

brain Circuit Mechanisms for Decision-Making in Health and Disease
 

William Carlezon

How experience affects the brain and behavior
 

Elena Chartoff

Molecular mechanisms and neural circuits of motivated behavior related to addiction in rodent models
 

Kathryn Commons

Understanding the contribution of central serotonin neurotransmission to behavior and psychopathology.
 

Ulf Dettmer

Modeling protein dyshomeostasis in Parkinson's disease and exploring strategies to correct it
 

Bradley Hyman

Neurobiology of neurodegenerative diseases using human, mouse, and culture systems, and employing advanced microscopy methods
 

Pascal Kaeser

Architecture and plasticity of neurotransmitter release sites
 

Rakesh Karmacharya

Neurobiology of disease: Chemical biology approaches in huan iPSC-derived neurons
 

Bernat Kocsis

Forebrain oscillations in rodent models of psychiatric diseases
 

Matt LaVoie

The role of proteostasis deficits and mitochondrial dysfunction in neurodegenerative diseases
 

Stephen Liberles

Internal and External Sensory Systems
 

Lauren Orefice

Development, function and dysfunction of the somatosensory system
 

Diego Pizzagalli

Clinical neuroscience and neurobiology of depression
 

Mustafa Sahin

Cellular Mechanisms of Neurodevelopmental Disorders and Epilepsy
 

Rudolph Tanzi

Genetic, molecular and biochemical studies of Alzheimer's disease from gene discovery to model systems to novel therapeutics
 

Naoshige Uchida

Neurobiology of decision-making
 
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Receptors & Ion Channels

Matthew Anderson

Molecular and Circuit Defects Underlying Human Genetic Forms of Autism and Epilepsy
 

John Assad

Cognitive processing in mammalian brain
 

Bruce Bean

Neuronal excitability and ion channel pharmacology
 

Nicholas Bellono

Sensory biology and cell physiology
 

Vadim Bolshakov

Cellular and network-level mechanisms of innate and learned fear
 

William Carlezon

How experience affects the brain and behavior
 

Elena Chartoff

Molecular mechanisms and neural circuits of motivated behavior related to addiction in rodent models
 

Chinfei Chen

Synaptic Plasticity in the CNS
 

Adam Cohen

Optical electrophysiology and neuronal biophysics
 

Sandeep Robert Datta

Functional and Behavioral Interrogation of Neural Circuits in the Mammalian Olfactory System
 

Michael Do

A Biophysical Approach to System Function
 

Rachelle Gaudet

Structural biology of signaling and transport across cellular membranes
 

Gwenaelle Geleoc

Functional development of sensory hair cells of the mammalian inner ear and gene therapy of Usher Syndrome
 

David Ginty

The functional organization of neural circuits underlying the perception of touch
 

Anna Greka

Ion channels and calcium signaling in health and disease
 

Jeffrey Holt

Sensory Transduction in Hair Cells of the Mammalian Inner Ear
 

Artur Indzhykulian

Hair cell mechanotransduction, stereocilia bundle morphology and ultrastructure, AAV gene therapy for Usher Syndrome
 

Pascal Kaeser

Architecture and plasticity of neurotransmitter release sites
 

Maria Lehtinen

Mechanisms of brain development, with a focus on the choroid plexus-cerebrospinal fluid system
 

Stephen Liberles

Internal and External Sensory Systems
 

Joseph Majzoub

Hypothalamic role in mammalian endocrine and behavioral responses to stress
 

David Paul

Intercellular Communication
 

Matthew Pecot

Molecular mechanisms underlying the assembly of neural circuits.
 

Bernardo Sabatini

Cellular and synaptic mechanisms of learning and development
 

Thomas Schwarz

Genetics of Neuronal Cell Biology
 

Brian Wainger

How abnormal physiology contributes to motor and sensory diseases.
 

Gary Yellen

Neuronal metabolism and excitability; Fluorescent biosensor imaging; K-ATP channels and anti-epilepsy mechanisms
 
top

 

Synapse Function & Plasticity

Mark Andermann

Circuit approaches to understanding selective processing of motivationally salient sensory stimuli
 

Matthew Anderson

Molecular and Circuit Defects Underlying Human Genetic Forms of Autism and Epilepsy
 

Paola Arlotta

Investigation of the molecular mechanisms governing development and reprogramming of neuronal subtypes in the mammalian cerebral cortex.
 

Sabina Berretta

Extracellular matrix/neuron/glia interactions in the pathophysiology of schizophrenia and bipolar disorder.
 

Vadim Bolshakov

Cellular and network-level mechanisms of innate and learned fear
 

William Carlezon

How experience affects the brain and behavior
 

Chinfei Chen

Synaptic Plasticity in the CNS
 

Sandeep Robert Datta

Functional and Behavioral Interrogation of Neural Circuits in the Mammalian Olfactory System
 

Benjamin de Bivort

Characterizing the molecular, neural circuit and ecological underpinnings of behavioral diversity in fruit flies.
 

Michael Do

A Biophysical Approach to System Function
 

Min Dong

Molecular mechanisms of synaptic transmission and botulinum neurotoxins
 

Fishell, Gord

The genetics, biochemistry and physiology of forebrain inhibition.
 

David Ginty

The functional organization of neural circuits underlying the perception of touch
 

Jesse Gray

Genomic mechanisms of neuronal activity-regulated transcription and its regulation of neuronal plasticity
 

Corey Harwell

Cellular and Molecular Mechanisms of Cortical Circuit Assembly
 

Bradley Hyman

Neurobiology of neurodegenerative diseases using human, mouse, and culture systems, and employing advanced microscopy methods
 

Ole Isacson

Neuron and glia disease mechanisms of age-dependent degeneration and repair
 

Joshua Kaplan

Genetic analysis of synaptic transmission
 

Wei-Chung Allen Lee

Structure, function, and development of neuronal networks
 

Jeff Lichtman

Studies of synaptic circuitry and their rearrangements
 

Bradford Lowell

Neural regulation of hunger, other homeostatic motivational drives, autonomic nervous system, and the neuroendocrine system
 

Venkatesh Murthy

Algorithms and Neural Circuits in Olfaction
 

Lauren Orefice

Development, function and dysfunction of the somatosensory system
 

Pehlevan, Cengiz

Theoretical neuroscience
 

Wade Regehr

Synaptic Transmission and Dendritic Processing
 

Kerry Ressler

Molecular Biology, Genetics, and Neural Circuitry of Fear in Animals and Human Fear-Related Disorders
 

Dragana Rogulja

The genetic and neural basis of sleep in Drosophila
 

Amar Sahay

Hippocampal circuit and plasticity mechanisms underlying memory processing and regulation of mood
 

Jie Shen

Mechanisms of neurodegeneration in Alzheimer’s and Parkinson's Diseases and development of novel therapies
 

Beth Stevens

Neuron-Glia Interactions During Development and Disease; Synapse Development and Plasticity; Neuro-Immune Interactions
 

Rudolph Tanzi

Genetic, molecular and biochemical studies of Alzheimer's disease from gene discovery to model systems to novel therapeutics
 

Hisashi Umemori

Synapse formation and refinement in the mammalian brain
 

Christopher Walsh

Development and disorders of the human cerebral cortex
 
top

 

Systems & Integrative Neuroscience

Mark Albers

Systems/Molecular Approaches to Elucidate Mechanisms that Cause Neurodegenerative Disease; Develop/Validate Novel Therapeutic Approaches
 

Mark Andermann

Circuit approaches to understanding selective processing of motivationally salient sensory stimuli
 

Matthew Anderson

Molecular and Circuit Defects Underlying Human Genetic Forms of Autism and Epilepsy
 

Todd E. Anthony

Genetic dissection of neural circuits that control stress-induced behavioral states
 

John Assad

Cognitive processing in mammalian brain
 

Brian Bacskai

Optical imaging in animal models of Alzheimer’s disease
 

Justin Baker

Deep phenotyping in mental illness
 

Nicholas Bellono

Sensory biology and cell physiology
 

Richard Born

Neural Circuitry of Primate Visual Cortex
 

Emery N. Brown

Neural Signal Processing and Mechanisms of General Anesthesia
 

Joshua Buckholtz

brain Circuit Mechanisms for Decision-Making in Health and Disease
 

Randy Buckner

Human neuroscience explorations of large-scale brain circuit function and dysfunction
 

William Carlezon

How experience affects the brain and behavior
 

Elena Chartoff

Molecular mechanisms and neural circuits of motivated behavior related to addiction in rodent models
 

Kathryn Commons

Understanding the contribution of central serotonin neurotransmission to behavior and psychopathology.
 

Michael Crickmore

Neurobiology of motivational states
 

Charles Czeisler

Physiology of the human circadian timing system and its relationship to the sleep-wake cycle
 

Benjamin de Bivort

Characterizing the molecular, neural circuit and ecological underpinnings of behavioral diversity in fruit flies.
 

Michael Do

A Biophysical Approach to System Function
 

Jan Drugowitsch

Statistical computations and neuronal mechanisms underlying complex decisions and behavior under uncertainty
 

Susan Dymecki

Specialization in the Serotonin System Shapes Behavior and Regulates Homeostasis
 

Florian Engert

To build a multi-scale model that describes how a living brain interacts with its environment
 

Elizabeth Engle

Cranial axon growth and guidance
 

Samuel Gershman

Computational cognitive neuroscience of learning and memory.
 

David Ginty

The functional organization of neural circuits underlying the perception of touch
 

Christopher Harvey

Neural circuits underlying cognitive behaviors in mice
 

Bradley Hyman

Neurobiology of neurodegenerative diseases using human, mouse, and culture systems, and employing advanced microscopy methods
 

Ole Isacson

Neuron and glia disease mechanisms of age-dependent degeneration and repair
 

Bernat Kocsis

Forebrain oscillations in rodent models of psychiatric diseases
 

Talia Konkle

Cognitive and neural architecture of high-level vision
 

Gabriel Kreiman

Visual object recognition: computational models and neurophysiological mechanisms
 

Wei-Chung Allen Lee

Structure, function, and development of neuronal networks
 

Maria Lehtinen

Mechanisms of brain development, with a focus on the choroid plexus-cerebrospinal fluid system
 

Stephen Liberles

Internal and External Sensory Systems
 

Margaret Livingstone

Visual perception, object recognition, higher cognitive functions, vision and art
 

Bradford Lowell

Neural regulation of hunger, other homeostatic motivational drives, autonomic nervous system, and the neuroendocrine system
 

Kun Ping Lu

Molecular mechanisms and treatments of Alzheimer’s disease and cancer
 

Joseph Majzoub

Hypothalamic role in mammalian endocrine and behavioral responses to stress
 

Richard Masland

Functional Organization of the Retina
 

Venkatesh Murthy

Algorithms and Neural Circuits in Olfaction
 

Victor Navarro

Neuroendocrine control of reproductive function and metabolism
 

Bence Ölveczky

Neural circuit mechanisms underlying the acquisition and control of complex motor sequences
 

Pehlevan, Cengiz

Theoretical neuroscience
 

Diego Pizzagalli

Clinical neuroscience and neurobiology of depression
 

Daniel Polley

Neuromodulation and plasticity in the auditory system
 

Kerry Ressler

Molecular Biology, Genetics, and Neural Circuitry of Fear in Animals and Human Fear-Related Disorders
 

Dragana Rogulja

The genetic and neural basis of sleep in Drosophila
 

Amar Sahay

Hippocampal circuit and plasticity mechanisms underlying memory processing and regulation of mood
 

Aravinthan Samuel

Sensory and Behavioral Neuroscience
 

Clifford Saper

Neural circuitry for hypothalamic functions, including wake-sleep, thermoregulation, drinking, feeding, and stress responses
 

Thomas Scammell

Neural circuitry of sleep and sleep disorders
 

Clemens Scherzer

Translational Genomics of Parkinson’s Disease: Cause, Cures, Diagnostics
 

Kristina Simonyan

Neurobiology of Speech Motor Control
 

Stelios Smirnakis

Principles of Neural Circuit Function and Malfunction in Disease States such as Epilepsy, Autism and Stroke
 

Naoshige Uchida

Neurobiology of decision-making
 

Ziv Williams

Human and primate social decision making, executive functioning and memory
 

Rachel Wilson

Neural computations and biophysical mechanisms underlying sensory processing and sensorimotor integration
 

Clifford Woolf

Adaptive and maladaptive plasticity in sensory and motor systems
 
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Current PiN Faculty

Total Number of Faculty: 135


Men: 102 (76%)

Women: 33 (24%)

 

Locations:

Beth Israel Deaconess Medical Center: 8

Boston Children's Hospital: 26

Brigham & Women's Hospital: 7

Dana Farber Cancer Institute: 2

Harvard Institutes of Medicine: 2

Harvard Medical School: 39

Harvard University: 19

Joslin Diabetes Center: 1

Massachusetts Eye and Ear Infirmary: 4

Massachusetts General Hospital: 14

MIT: 1

McLean Hospital: 11

Schepens Eye Research Institute: 1


 


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of Harvard College