Leder Medical Sciences
 DMS Home  /  About DMS  /  Current Student Resources  /  Contact Us  /  Search 

Leder Medical Sciences Program Summary

LMS Information Session

There will be an information session to introduce the Leder Medical Science Program for all first year HILS students. It will be held on Oct. 15, 5-6 PM, with light refreshments, in the NRB room number 350, on the medical school campus. This session will allow you to learn about the LMS Program, how to apply, and the time table for various aspects of the Program. Any first year HILS student is eligible for the Program. Members of our first two classes of LMS students will be in attendance so that you can meet and talk to them as well.

Applications are due Nov. 5, 2007. Download application here.

Introduction

The future success of translational research relies upon dedicated and talented individuals who are well versed in the science of human biology. To provide formal training in this area for Harvard life sciences PhD students, we are establishing the Leder Medical Sciences (LMS) Program, honoring Dr. Phillip Leder, outgoing Chair of the Department of Genetics at Harvard Medical School. This Program is for HILS PhD students and will be initiated in the spring semester of 2006. An outline of the Program is given below. The Program Administration, with contact information, is listed below.

Outline of LMS Program

The LMS Program has two goals. First, it will provide PhD students with a working knowledge of the fundamentals of human biology and disease, primarily through a series of courses, to enrich their basic science training and broaden their research interests. Second, it will demystify the culture and practice of medicine, facilitating future collaborations with clinicians and physician-scientists, through activities designed to bring students into a hospital environment into direct contact with physicians, patients, medical students, and physician-scientists. The full program runs for one and one half years, beginning in Spring of the G1 Year, and it will be interdigitated with a student’s other graduate program requirements. Students who successfully complete the LMS Program will receive a certificate of distinction with their PhDs. Students who do not enter the LMS program but wish to learn about human biology will have access to all LMS courses on an ad hoc basis. After the formal LMS Program is completed, students will be encouraged to continue to develop careers in human biology through ongoing mentoring and extracurricular activities throughout their time at Harvard. However, there is no requirement that a student undertake thesis research in a laboratory that is working on human biology or disease as any type of basic science is considered to be vital and fundamental for the goal of understanding and treating human disease.

Application

Students in Year 1 of any HILS program are invited to apply. A short application and an interview with members of the LMS Admissions Committee will be required. Evidence of a commitment to this type of training and good academic standing will be the criteria upon which applicants will be judged. If there is a greater number of qualified applicants than slots available, a lottery will be held. An application will be distributed in late October/early November and decisions will be made by the holiday break in December 2007.

Course Requirement

The curriculum does not replicate the pre-clinical coursework taken by medical students; rather, it focuses on knowledge and concepts of particular use to biomedical investigators. To this end, there are 3 full semester courses and one quarter course that are required. BCMP 234. Metabolism (a course taught for the first time in Spring 2007), HT 035. Principles and Practice of Human Pathology (offered at MIT), and Med Sci 220. Human Pathophysiology are the full semester courses. BCMP 234 and HT 035 are taken in the Spring semester of Year 1. MedSci 220 is taken in Fall of Year 2. MedSci 220 was being offered for the first time in the Fall of 2006 and is a course designed for PhD students. It introduces fundamental homeostatic mechanisms and organ systems, covering both normal and disease states. Several longitudinal themes (immunology, cancer, genetics, and developmental abnormalities) integrate concepts across organ systems. Students observe physiology in practice through field trips to clinical outpatient units (e.g., a dialysis unit, an exercise physiology lab, a cardiac function lab) and the operating room. The one required quarter course is BCMP300. Translational Pharmacology. This is a 9 day course in January which will be taken in Year 2. It is taken with physicians of the Clinical Scholars Program, with projects developed by small groups of LMS students and physicians.

In addition to the above courses, one full semester and one quarter elective course are required. These will be chosen in consultation with an LMS Program Advisor to allow students to broaden their exposure to human biology and to study selected topics (e.g., immunology, neuroscience, human genetics, infectious disease, epidemiology) in greater depth. Electives include a subset of courses currently available to medical and graduate students. They can include quarter courses or nanacourses. A list of some of the courses that satisfy elective requirements is available, and many more courses can be chosen for this requirement.

All courses taken for the LMS Program can be counted towards a student’s requirements for their PhD Program, as allowed by each individual PhD Program.

Clinical Experiences

In parallel with formal courses, LMS students will have structured opportunities to learn about the culture of medicine and explore roles for basic scientists in clinical settings. LMS students will attend pre-selected clinical conferences at the major teaching hospitals and meet with physicians to discuss conference topics in a journal club format. In Year 2 of the Program, they will engage in the Mentored Clinical Case Book Project (MCCB or MR700). In this course, each LMS student will follow a patient longitudinally and develop their observations into a written case. They will be introduced to the patient by the patient’s physician, and will meet in small groups with medical students and a faculty mentor to develop the case. In addition to these activities, LMS students will have seminar sessions with hospital fellows and junior faculty to learn about translational investigation. Each LMS student will also be assigned a clinical mentor, chosen according to the student’s research interests.

Links:

Coming Soon.

LMS Program Administration

Director

Connie Cepko

Professor of Genetics
HMS, Genetics
NRB 360
cepko@genetics.med.harvard.edu
617-432-7618
NRB 360

Associate Directors

Frank Bunn

Professor of Medicine
Brigham & Womens Hospital
hfbunn@rics.bwh.harvard.edu
617-355-9068
Karp Building, Room 5215

Jim Adelstein

Paul C. Cabot Distinguished Professor of Medical Biophysics
HMS, Pathology
TMEC 145
james_adelstein@hms.harvard.edu
617-432-3997

Thomas Michel

Professor of Medicine
Brigham and Women’s Hospital
Thorn Building 1210A
617-732-7376
tmichel@research.bwh.harvard.edu
Thorn Building 1210A

Steering Committee

David Altshuler

Assoc. Prof. of Genetics
MGH, Genetics
altshuler@molbio.mgh.harvard.edu
617-726-5940
Richard B. Simches Research Bldg
185 Cambridge St, CPZN-6818

Pat D’Amore

Prof. of Ophthalmology
Schepens Eye Institute
pdamore@vision.eri.harvard.edu
617-912-2559
Opthalmology, 20 Stanford St., 2 West

Elizabeth Engle

Assoc. Prof. of Neurology
CHB, Neurology
engle@enders.tch.harvard.edu
617-919-4030
Enders 560.2, Div. of Genetics

Randy King

Assist. Prof. of Cell Biology
HMS, Cell Biology
randy_king@hms.harvard.edu
617-432-3629
Seeley G. Mudd Bldg. 604

Elio Raviola

Bullard Prof. of Neurobiology
HMS, Neurobiology
elio_raviola@hms.harvard.edu
617-432-1742
B2-201

Heidi Rehm

Instructor in Pathology/Markey Alumnus
Harvard-Partners Ctr. for Genetics & Genomics
rehm@helix.mgh.harvard.edu
617-768-8291
65 Landsdowne Street
Cambridge, MA

David Reich

Assist. Prof. of Genetics
HMS, Genetics
reich@receptor.med.harvard.edu
617-432-6548
NRB 336

Jeffery Tong

Vice President/Markey Alumnus
Infinity Pharmaceuticals
Jeffrey.Tong@ipi.com
617-453-1198
780 Memorial Dr.
Cambridge, MA