Address and Contact Information
Harvard Graduate Program in Immunology
Harvard Medical School
Jeffrey Modell Immunology Center, Room 100D
Boston, MA 02115
view map of the Longwood Medical Area
For complete course listings, including syllabi, click here.
Immunology 201. Principles of Immunology
Thorsten Mempel, Michael Carroll, Ulrich H. Von Andrian-Werburg, and members of the Department
Half course (fall term). Tu., Th., 1:30-3, with section Tu., Th., 3-4.
As a comprehensive core course in immunology, the topics include a broad but intensive examination of the cells and molecules on the immune system. Special attention is given to the experimental approaches that led to the general principles of immunology.
Note: Background in genetics and biochemistry is strongly recommended. Prerequisite: this course is intended for students who have had prior exposure to immunology at the undergraduate level. In the absence of such exposure, students MUST obtain the permission of the Course Director.
Immunology 202. Advanced Principles of Immunology
Filip Swirski and Mikael Pittet
Half course (spring term). Tu., Th., 1:30-4:00pm.
IMM202 builds on IMM201 and explores fundamental principles of immunology in the context of immune and inflammatory diseases. Through a series of lectures and discussion, students will survey a broad range of diseases in which the immune system is essential. Topics will include not only diseases that mobilize classical immunity but also conditions to which we now know the immune systems contribute. Students will use oral and written exercises to learn how to evaluate and synthesize major concepts and tools germane to immunology’s relationship to bioscience.
Prerequisite: Immunology 201 or its equivalent.
Immunology 204. Critical Reading for Immunology
Half course (spring term). Th., 10am-1pm.
Original research articles from fields including immunology, biochemistry, genetics, and cell and developmental biology will be critically analyzed in an intensive small group format. Grading will be based on class participation and oral presentations.
Required for first-year immunology students; open to second-year students. No auditors allowed.
Immunology 301. Immunology Seminar Discussion Course
Michael Carroll and Nicholas Haining
Half course (fall and spring terms). Wed., 3:30-5pm.
Gives students exposure to research topics in immunology. Students prepare for the weekly seminar through readings and discussion with seminar speakers. These discussions are facilitated by members of the Committee on Immunology.
Note: Required for, and limited to, first-year Immunology graduate students.
Immunology 301qc. Autoimmunity
Kai Wucherpfennig and Francisco Quintana
Quarter course (spring term). M., 4–6.
This course will focus on basic immunological mechanisms of autoimmune diseases,
with an emphasis on recent advances in the field. At each session, we will focus on a
particular topic and discuss three important publications.
Immunology 302qc. Clinical Sessions in Immunology
Quarter Course (spring term).
Lectures by physician scientists and clinical exposure to patients with immunologically mediated diseases. The goal is to foster translational research into human immunologic disease. Formulate grant proposals that address critical questions for understanding or treatment of human immunologic disease.
Note: Limited to Immunology students. Hours for clinical visits to be arranged.
Immunology 303qc. The Warring Genomes: Innate Immunity and Host Defense
Jonathan C. Kagan
Quarter course (spring term). Tuesdays, 4-6 pm.
Focus on basic cellular and molecular aspects of innate immunity, with an emphasis on recent advances in the field. Each class will cover a specific topic, and supporting literature will be provided by the instructor.
Prerequisite: Students are expected to have already taken IMM 201.
Immunology 305qc. Neuro-immunology in development, regeneration and disease
Isaac Chiu, Michael Carroll, and Beth Stevens
Quarter course (spring term). Th., 4–6:30pm.
It is increasingly clear that the nervous system and immune system share parallel molecular pathways, and communication between neurons and immune cells play significant roles in homeostasis and disease. This course will investigate current topics in neuro-immunology: CNS development, chronic pain, neuro-degeneration, aging, axon regeneration, auto-immunity and infection. We will focus our discussions on molecular mechanisms shared by the immune and nervous systems and the molecular cross-talk between these two systems.
Each class will cover a specific topic in neuro-immunology. Students should be prepared to lead discussions on pre-selected papers for each session.
Immunology 307qc. Cancer Immunology
Kai W. Wucherpfennig, Catherine Wu, Stephanie Dougan and Michael Goldberg
Quarter course (fall term). M., 4–6.
There have been many exciting recent developments in the cancer immunology field, and multiple therapeutic approaches have shown efficacy against diverse types of cancer. This course will emphasize new mechanistic insights, in particular on the following topics: Mechanisms of spontaneous protective anti-tumor immunity; Key effector cell populations of anti-tumor immunity; Inflammation and tumor microenvironment; Immunosuppressive mechanisms in tumor immunity; Targeting of inhibitory receptors; Cancer vaccines; New approaches for delivery of immunotherapies into tumors.
Immunology 308QC Transformational Immunology – Research and Papers that Changed the Field
Laurence Turka and Shiv Pillai
Quarter course (fall term). Wednesday., 9:30-11:30 AM
This is a reading course with central themes on advances in immunology that created new paradigms and changed the field. There will be a reading requirement of 2-3 relevant papers on the topics of discussion for each week. Each session will consist of a student-led presentation of background on the topic (which will consist of a brief introduction followed by a discussion involving the whole class) followed by another student’s presentation of the key points of the papers and how the new findings transformed the field. Each student is expected to make two presentations during the seven-week course. Evaluation is based on presentations and class participation.
Course Prerequisite: Enrollment in the immunology PhD program. Other applicants need permission of the course director.
Immunology 328r. Introduction to Research
Michael Carroll and faculty members
Three required laboratory rotations in immunology each lasting 10-12 weeks per laboratory. To be arranged by students with investigators affiliated with the immunology program.