Peter H. Schur

Department of Rheumatology/Immunology
Brigham and Women's Hospital
PBB-B2, 75 Francis Street
Boston, MA 02115
Tel: 617-732-5350
Fax: 617-732-5505
e-mail:pschur@partners.org
1 postdoctoral fellow

My research revolves around the following: Genetics of Systemic Lupus Erythematosus (SLE): In collaboration with Dr. Patricia Fraser (Dept. of Medicine/Div. of rheumatology BWH) we are continuing to explore the role of genetics in SLE, in particular genes in the MHC as well as T cell receptor genes. Neuropsychiatric aspects of SLE: In collaboration with Drs. Shah Khoshbin and Dr. Bonnie Glanz (Dept . of Neurology, BWH) we are conducting a long-term study of cognitive defects in patients with SLE. Long term studies of neuropsych testing are being correlated with EEG, MRI, and immunological abnormalities. Anti-phospholipid antibodies: We have developed two new assays for the detection of antibodies to prothrombin and to beta (2) glycoprotein 1. The presence of these antibodies, as well as other anti-phospholipid antibodies (e.g. anti-cardiolipin antibodies and lupus anticoagulant) is being associated with clinical and laboratory parameters in these patients. We have added a new diagnostic assay for rheumatoid arthritis, Anti-CCP, and one evaluating it.

Papers & Publications:

Schur PH and Kammer GM. Treatment of Systemic Lupus Erythematosus. In Modern Treatment of Rheumatic Diseases. Ed by GC Tsokos. Humana Press, Totowa NJ, 2002, pp 259-296.

Schur PH. Recognizing and treating chronic fatigue. Women1s Health in Primary Care 2002; 5:288-313.

Kowal K, Schacterele RS, Schur PH et al. Prevalence of allergen-specific IgE among patients with chronic fatigue syndrome. Allergy and Asthma Proc 2002; 23:35-39.

Glanz BI, Laoprasert P, Schur PH, Robertson-Thompson A, Khoshbin S. Lateralized EEG findings in patients with neuropsychiatric manifestations of systemic lupus erythematosus. Clinical Electroencephalography 2001: 32: 14-19.

Karlson EW, Tanasijevic M, Hankison SE, et al. Monoclonal gammopahty of unde termined significance and exposure to breast implants. Arch Int Med 2001; 161:864-867.