My research revolves around the following: Genetics of Systemic Lupus Erythematosus (SLE): In collaboration with Dr. Patricia Fraser and Karen Costenbader (Dept. of Medicine/Div. of Rheumatology BWH); we are continuing to explore the role of antibodies to acute phase reactants such as C-reactive protein (CRP) and tissue necrosis factor (TNF) as well as to citrullinated proteins (e.g. CCP) in patients with SLE, rheumatoid arthritis (RA) and related rheumatic and immune disorders; as well as the continued collaboration with Dr Shah Khoshbin (Dept Neurology, BWH) on Neuropsychiatric aspects of SLE; in collaboration with Dr E Massarotti (Rheumatology BWH) we are performing therapeutic trials of new medications for the treatment of SLE.
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Papers & Publications:
Glanz B, Schur PH, Law RA, Khoshbin S. Laterized cognitive dysfunction in patients with systemic lupus erythematosus. Lupus 2005; 14:896-902.
Rosenau BJ, Schur PH. Antibodies to C reactive protein. Ann Rhuem Dis 2006; 65:674-676.
Costenbader KH, Chibnik LB, Schur PH. Discordance between erythrocyte sedimentation rate and C-reactive protein measurements; clinical significance. Clin Exp Rheumatol 2007; 25: 746-9.
Rosenau BJ, Costenbader KH, Schur PH. C-reactive protein, anti C-reeactive protein antibodies and clinical atherosclerosis. Vascular Medicine 2008; 13:25-28.
Lee DM, Phillips R, Hagan EM, Chibnik LB, Costenbader KH, Schur PH. Quantifying anti-CCP titer: clinical utility and association with tobacco exposure in patients with rheumatoid arthritis. Ann Rheum Dis 2008 In press. |
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