BIG Faculty Member - Scott Weiss, M.D.

Scott Weiss, M.D.

Physician, Brigham and Women's Hospital
Professor of Medicine, Harvard Medical School

Channing Laboratory
181 Longwood Ave.
Room 461
Boston, MA 02115
Tel: 617-525-2278
Visit my lab page here and here.

I am Professor of Medicine at Harvard Medical School and Director of Personalized Medicine (PPM) at Partners HealthCare System, where I am responsible for 15 faculty and ~100 staff that work in our Core Laboratories, the Partners Biobank, our CLIA-approved Laboratory for Molecular Medicine (LMM) and our IT and Education programs. In this capacity I help set priorities around personalized medicine for the Partners HealthCare system (MGH and BWH).

I am also Co-Leader of the Systems Genetics and Genomics Unit (SGGU) in and Associate Director of the Channing Division of Network Medicine (CDNM) at Brigham and Women’s Hospital (BWH). The research facilities I oversee use the state-of-the-art technologies and technological platforms and methods for genetic and genomic research. At the CDNM, I co-lead a 30-investigator, 110-person research group involved in examining the environmental exposures and genetic risk factors for the development of asthma and COPD. With the Division Chief, Dr. Edwin K. Silverman, I am responsible for the administrative aspects of this Unit, as well as my own research. My group at CDNM has close working relationships with the PPM, the Departments of Environmental Health and Biostatistics at the Harvard T.H. Chan School of Public Health (HSPH), where I am Professor of Environmental Health in the Respiratory Biology Program, and the Division of Pulmonary and Critical Care Medicine at BWH.

I have led multi-disciplinary cooperative studies of asthma and COPD and I have international research experience in China, Norway, Mexico, England/UK, Costa Rica and the Netherlands. I have served in leadership capacities in a variety of on cooperative and collaborative studies, such as CAMP, SHARE and EVE, and have served in administrative capacities in the NHLBI of the NIH for a variety of genetic epidemiologic programs including the SEP on the Use of NHLBI Specimens, the Oversight Committee for the Collaborative Study on the Genetics of Asthma, the NHLBI Genotyping Service Study Section and the oversight panel for the Genotyping and Sequencing Service.

I have authored or co-authored over 600 papers and co-written and co-edited 4 books, including a comprehensive textbook on Respiratory Genetics. I have been continuously funded by the NIH/NHLBI for 40 years and was recently identified as part of the top 0.004% of biomedical researchers in terms of the scientific impact of their work (Eur J Clin Invest. 2013;43(12):1339-65. PMID: 24134636).

My long-standing research interests have been in the area of environmental and genetic risk factors for the development of asthma and COPD and now include pharmacogenetics/pharmacogenomics of airway disease, the fetal and natural development of asthma, the role of vitamin D supplementation during the prenatal period on various outcomes, personalized medicine and the development and application of new technologies into clinical practice. I have a total of six NIH funded grants on which I am PI or Co-PI including a MERIT award.

I have personally mentored 41 post-doctoral trainees for nearly 30 years, all but two of whom continue to pursue academic research, and remain committed to mentoring new investigators and junior faculty. As an experienced and senior investigator, I have been the leader or co-leader of our T-32 training grant for the past 30 years and of our K-12 grant for the last 10 years.

Last Update: 11/27/2017


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