BIG Faculty Member - Edwin Silverman, M.D., Ph.D.

Edwin Silverman, M.D., Ph.D.

Brigham and Women's Hospital
181 Longwood Ave
5th Floor, Room 537
Boston, MA 02115
Tel: 617-525-0856
Visit my lab page here.

I am a pulmonologist and genetic epidemiologist. I am the Principal Investigator of multiple studies of COPD genetics, including an extended pedigree study designed to identify novel genetic determinants of severe, early-onset COPD (Boston Early-Onset COPD Study) and the Genetic Epidemiology of COPD Study (COPDGene; I am one of two Principal Investigators), which has created a large cohort of COPD cases and controls with comprehensive pulmonary phenotyping (including chest CT scans) for genetic studies. I am also collaborating on several other studies of COPD genetics, including the International COPD Genetics Network and the ECLIPSE Study. I am also the Chief of the Channing Division of Network Medicine at the Brigham and Women’s Hospital, where we are using network science approaches to analyze genetic, genomic, and phenotypic data in complex diseases. I am the co-director of the Channing T32 and K12 training programs, and I have mentored 22 post-doctoral fellows. Since its inception, I have been the Principal Investigator of the Functional Genetics of COPD Program Project Grant, which is focused on integrating genetic, gene expression, and epigenetic data to provide insight into the biological mechanisms of COPD genetic determinants.

Last Update: 11/27/2017


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