BBS Faculty

 

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z

 

Faculty Name Research Summary
Abzhanov, ArkhatOral Developmental Biology
Ahmad, KamiHistone variants and chromosome biology
Alt, FrederickLymphocyte Differentiation, Recombination, DNA repair, cancer
Altshuler, DavidGenomic approaches to human disease genetics
Anderson, PaulRNA granules
Arany, ZoltanGene Regulation of Metabolism in Cardiovascular Health and Disease
Arlotta, PaolaMolecular and Developmental Neurobiology
Arnaout, M. AminAdhesion, Integrins, hematopoiesis, kidney genetics
Artavanis-Tsakonas, SpyrosMolecular Genetics of Cell Interaction in Development
Aster, JonRole of Notch Signaling in Lymphoid Neoplasia
Ausiello, DennisMembrane Biology
Ausubel, FrederickMolecular Biology of Pathogenesis
Avidor-Reiss, TomerCentriole, Centrosome and Cilium: Biogenesis, Function and Evolution
Baron, RolandBone cells differentiation, function and signaling
Beggs, AlanMolecular genetics of human neuromuscular diseases
Beier, DavidMouse Models of Human Disorders
Bender, WelcomeDrosophila Molecular Genetics
Bernhardt, ThomasBacterial cell division and cell biology
Bernstein, BradleyEpigenetic mechanisms in mammalian development
Biddinger, SudhaMechanisms by which diabetes promotes atherosclerosis
Bischoff, JoyceEndothelial Progenitors in Health and Disease
Blacklow, StephenBiochemistry of transmembrane receptors and signaling
Blackwell, T. KeithAging, Stress Defenses, and Developmental Gene Regulation in C. elegans
Blenis, JohnMolecular Biology of Cell Growth Regulation and Transformation
Blower, MichaelMicrotubule associated RNAs during mitosis
Bonni, AzadCell-Intrinsic Regulation of Neuronal Connectivity in Brain Development and Disease
Bradner, JamesGene regulation studied with small molecules
Breault, DavidRegulation of tissue stem cells
Brenner, MichaelInnate - Adaptive Immunity and Autoimmunity
Brugge, JoanSignal transduction in normal and transformed cells
Bulyk, MarthaTranscription Factors and DNA Regulatory Elements
Buratowski, SteveBiochemical and Genetic Analysis of Eukaryotic Gene Expression
Burns, CarolineCardiovascular stem cell biology
Camargo, FernandoStem cells and organ size control
Campbell, JamesTissue-specific lymphocyte homing and diversity
Cantley, LewisSignal Transduction
Cantor, Alan Transcription factors in hematopoiesis and leukemogenesis
Carroll, MichaelGenetic Models of Human Disease
Cepko, ConnieMolecular genetics of neural development and gene therapy to prevent blindness
Chan, JoanneDissection of angiogenic signaling in zebrafish
Chien, KennethCardiovascular Stem Cells in Development and Disease
Chou, JamesProtein NMR Spectroscopy of Membrane Protein
Chowdhury, DipanjanDownregulating DNA Repair: Phosphatases & MicroRNAs
Church, GeorgeGenome Structure
Churchman, StirlingGlobal studies of transcription elongation
Cichowski, KarenCombining genetic and biochemical approaches to elucidate mechanisms underlying cancer
Clapham, DavidNew Biology through Physics: Molecular Discoveries with Light
Clardy, JonBiologically active small molecules
Coen, DonaldMolecular Genetics of Herpes Viruses
Cohen, DavidMechanisms of hepatic cholesterol elimination
Colaiácovo, MonicaMechanisms underlying accurate meiotic chromosome segregation
Corfas, GabrielMolecular Basis of Neuron Glia Interactions
Cowan, ChadStem Cells and Developmental biology
D'Amore, PatriciaRegulation of Vascular Development and Pathology
D'Andrea, AlanGenomic instability and cancer susceptibility
Daley, GeorgeStem cells in disease and development
Daly, MarkGenetics of common human disease
Danial, NikaIntegration of Metabolism and Stress Pathways
Danuser, GaudenzMechanochemical cell signaling
Datta, SandeepFunctional Characterization of Neural Circuits
De Jager, PhilipHuman genetics of neuroinflammatory and neurodegenerative disorders
DeCaprio, JamesCellular transformation by SV40
DePace, AngelaMechanism and evolution of gene expression in Drosophila
Donahoe, PatriciaDevelopmental Biology / Genetics (congenital anomalies, cancer)
Dove, SimonThe regulation of gene expression in pathogenic bacteria
Drapkin, RonnyCancer pathogenesis: models, mechanisms, and biomarkers
Drummond, IainGenetic analysis of zebrafish kidney organogenesis
Dulac, CatherineMolecular and Development Neurobiology
Dymecki, SusanDevelopmental Neurobiology and Genetics
Dyson, NicholasControl of Cell Proliferation by RB/E2F
Ebert, BenjaminResearch in hematology and oncology
Eck, MichaelStructure Biology of Cytoplasmic Signal Transduction
Eggan, KevinMechanisms of Epigenetic Reprogramming
Elion, ElaineMolecular Mechanisms of Signal Transduction
Elledge, StephenCell Cycle Control and Genomic Integrity
Engelman, AlanRetroviral DNA Integration
Engle, ElizabethGenetic disorders of axon growth and guidance
Evans, DavidPrimate lentiviral immunology and pathogenesis
Extavour, CassandraComparative and evolutionary invertebrate developmental biology
Farzan, MichaelHIV-1 and Other Viruses
Feany, MelGenetics of neurodegenerative disease
Finley, DanielThe ubiquitin-proteasome pathway
Fisher, DavidEukaryotic survival decisions
Flanagan, JohnCell-cell signaling in neural development and regeneration
Fleming, MarkMolecular genetics of erythroid iron metabolism
Fontana, WalterSystems Biology Research
Francis, NicoleBiochemistry of Epigenetics
Frank, DavidIntracellular signaling pathways in the regulation of cell growth and differentiation
Garcia-Cardeña, GuillermoControl of Endothelial cell fate and vascular development by fluid mechanical forces
Garraway, LeviIntegrated and functional genomic studies of human cancer
Gaudet, SuzanneSystems biology of mammalian cell fate decisions
Gehrke, LeeRNA Structure, RNA-protein Interactions, and Translation-level Gene Regulation in RNA Viruses
Gilmore, MichaelMolecular biology multi-drug resistant pathogens
Gimbrone, MichaelTopics in Vascular Biology
Gimelbrant, AlexanderEpigenomics of allele-specific expression
Gladyshev, VadimRedox biology, trace elements and aging
Goessling, WolframLiver development, regeneration and carcinogenesis
Golan, DavidRegulation of Membrane Protein and Lipid Dynamics: Molecular Mechanisms and Biological Implications
Goldberg, Alfred Mechanism and Function of Intracellular Protein Turnover
Goldberg, MarciaPathogen-host interactions
Goodrich, LisaMolecular genetic dissection of circuit assembly and morphogenesis
Goodyear, LaurieEffects of diabetes, exercise, and skeletal muscle metabolism
Gray, JesseHow transcriptional networks rewire neuronal circuits
Gray, NathanaelFunctional small molecules for biological discovery
Greenberg, MichaelNeurological Control of Cell Growth and Differentiation
Gregory, RichardMechanisms of RNAi in stem cells
Gu, ChenghuaThe molecular mechanisms of how neural and vascular networks are coordinately developed
Gusella, JamesMolecular Genetics of Inherited Disorders
Gussoni, EmanuelaMuscle stem cell commitment and differentiation
Gygi, StevenMass Spectrometry and Proteomics
Haber, DanielCharacterization of molecular targets of cancer therapy
Hahn, WilliamMolecular approaches to cell immortalization and transformation
Haigis, KevinRas signaling and colon cancer
Haigis, MarciaMitochondria in aging and metabolism
Harper, J. WadeMechanism and biology of ubiquitin-like protein conjugation cascades
Harris, MatthewGenetic basis of skeletal development and evolution
Harrison, StephenStructure of Viruses, Viral Proteins, Receptors, Transcription Factors
Hazra, AditiGenomic and epigenomic susceptibility to cancer
He, XiMolecular mechanism of signal transduction
Heiman, MaxwellCell shape
Henske, ElizabethTuberous sclerosis and LAM: Pathogenic Mechanisms
Higgins, Darren Molecular Determinants of Intracellular Bacterial Pathogenesis
Higgins, JonathanMitotic kinases, chromatin and chromosome segregation
Hirschhorn, JoelHuman genetics, Genomics and Complex Traits
Hochedlinger, KonradEmbryonic stem cells, Nuclear Transfer, Cancer, Reprogramming
Hochschild, AnnGene Regulation of Prokaryotes
Hock, HannoTranscriptional control of hematopoiesis and leukemia
Hogle, JamesX-Ray Crystallographic Studies of Viruses and Proteins
Howley, PeterViral Pathogenic and Tranformation Mechanisms
Hsu, VictorBasic and applied mechanisms of intracellular transport
Hung, DeborahChemical genetics approach to bacterial pathogenesis
Hunter, CraigGenetics and Development
Hur, SunInnate immunity against RNA viruses
Husson, RobertMycobacterial signal transduction and transcription regulation
Iliopoulos, DimitriosMolecular Links between Inflammation and Oncogenesis
Ingber, DonResearch in Integrin Signaling, Cytoskeleton, and Control of Angiogenesis
Italiano, JosephCytoskeletal mechanics of blood platelet production
Jackson-Grusby, LaurieEpigenetic regulation in development and disease
Jain, RakeshTumor microenvironment, Angiogenesis and Metastasis: from Bench-to-Bedside-to-Biomarkers
Janne, PasiTranslational research on kinase inhibitors
Jensen, FrancesAge-Dependent Mechanisms of Perinatal Brain Injury
Joung, J. KeithMolecular recognition and protein engineering
Kagan, JonathanToll-like Receptors and Innate Immunity
Kahn, C. RonaldCellular and Molecular Aspects of Insulin Action
Kahne, DanielMechanisms of action of antibiotics
Kalluri, RaghuMatrix biology, cell-matrix interactions in health and disease
Kaplan, JoshuaGenetic analysis of synaptic transmission
Karnoub, AntoineEpithelial:stromal interactions in the formation and progression of carcinomas
Kasper, DennisBacterial / Host Interactions in symbiosis and pathogenesis
Kazlauskas, AndriusMolecular basis of human disease
Khosravi-Far, RoyaSignal transduction pathways involved in cellular proliferation and apoptosis
Kieff, ElliottMolecular biology of Epstein Barr Virus infection and transformation of B Lymphocytes
Kim, CarlaLung stem cell biology and cancer
King, RandyChemical Approaches to Cell Division and Cancer
Kingston, RobertMolecular Mechanisms of Transcription Regulation in Mammals
Kirchhausen, TomasSingle-molecule biology and visualization of cellular dynamics
Kirschner, MarcCell Morphogenesis and Regulation
Klagsbrun, MichaelGrowth Factor Structure and Function
Knipe, DavidMolecular Biology of Herpes Viruses
Kohane, IsaacIntegrative genomics of cancer and autism
Kontaridis, MariaSignal Transduction and Phosphorylation in Heart Disease
Kreidberg, JordanSignaling networks in development and disease
Kucherlapati, RajuGenetics and genomics of human disease
Kuhn, BernhardMyocardial regeneration, heart muscle cell proliferation
Kulkarni, RohitIslet cell signaling mechanisms, Stem cells, iPS Cells in diabetes
Kunkel, LouisNeurogenetics of Disease
Kupper, ThomasSkin Immunology T cell Trafficking Lymphoma
Kuroda, MitziMolecular genetics of chromosome organization and gene expression
Kwiatkowski, DavidHuman molecular and cancer genetics
Lahav, GalitProtein dynamics in single living cells
Langenau, DavidSelf-Renewal and Cancer
Lassar, AndrewRegeneration of cartilage and skeletal muscle
Lee, CharlesStudying human diseases through structural genomic variation
Lee, JeannieMechanism of X-inactivation in Mammals
Lehtinen, MariaNeural stem cells and cerebrospinal fluid
Lencer, WayneBacterial toxin entry and immunoglobulin transport in mucosal epithelial cells
Lesser, CammieModeling mechanisms of bacterial pathogenesis
Letai, AnthonyTargeting apoptosis regulation in cancer
Letvin, NormanImmunopathogenesis of Viral Diseases
Levy, BruceResolution of lung inflammation and injury
Levy, OferTranslational immunology in immunocompromised hosts
Li, ZheDevelopmental oncobiology and cancer stem cells
Liao, RonglihCardiac repair and regeneration
Liberles, StephenMolecular Biology of Instinctive Animal Behavior
Lieberman, JudyCytotoxic T Lymphocytes
Liu, X. ShirleyComputational biology of transcriptional and epigenetic regulation.
Livingston, DavidMolecular biology and genetics of Cancer
Look, A. ThomasGenetic models of Leukemogenesis
Loparo, JosephSingle-molecule studies of DNA repair
Lory, StephenHost Pathogen interactions
Loscalzo, JosephEndothelial cell, nitric oxide, proteomic redox regulation
Losick, RichardMicrobial Development
Lu, Kun PingCell Growth Regulation, Telomere Maintenance, cancer and Alzheimer's disease
Luo, HongboCell signaling in innate immunity
Maas, RichardGenetic regulation of organogenesis and organ regeneration
Mably, JohnModels of cardiac development and disease
MacDonald, MarcyMolecular Genetic Approaches to Human Disease Mechanisms
Macklis, JeffreyNeo-Cortical Development and Cellular Transplantation
MacRae, CalumCardiovascular Biology in Human and Zebrafish
Majzoub, JosephHypothalamic gene function and regulation
Malley, RichardAcquired and innate immunity to pneumococci
Mango, SusanEnvironmental Signaling, Plasticity and Fate Specification during Development
Marasco, WaynePrinciples/Practices of Developing Human Antibody Therapies
Marto, JarrodQuantitative proteomics of cancer progression
Mayadas, TanyaPhagocyte-endothelial cell responses in inflammation
McAllister, SandraMolecular and cellular regulators of cancer progression
McCarroll, StevenHuman genome structural and regulatory variation
McClatchey, AndreaMembrane:cytoskeleton interface in morphogenesis and tumorigenesis/metastasis
McKeon, FrankThe Structure of the Nucleus and the Dynamics of Nuclear Transport
Megason, SeanSystems Biology Research
Meissner, AlexanderEpigenetic modifications and cellular identity
Mekalanos, JohnMolecular Mechanisms in Pathogenesis
Melton, DouglasVertebrate Development Biology
Meselson, MatthewBiology of Aging
Meyerson, MatthewBiology and genetics of human cancers
Michel, ThomasCardiovascular signal transduction
Mitchell, RichardMechanisms of acute and chronic allograft rejection
Mitchison, TimothyCytoskeletal Dynamics
Moazed, DaneshGene Silencing and Chromosome Structure
Mootha, VamsiSystems Biology Research
Mora, JorgeTissue-specific leukocyte trafficking in health and disease.
Morton, CynthiaResearch in Molecular Cytogenetics
Moses, MarshaBiochemical and molecular regulation of vascular growth
Mostoslavsky, RaulChromatin Dynamics in metabolism and DNA repair
Mulligan, RichardDevelopment Applications of Mammalian Vectors
Münger, KarlViral Oncoproteins as Probes to Study the Regulation of Cell Growth and Differentiation
Näär, AndersMolecular mechanisms of transcriptional control
Newton-Cheh, ChristopherComplex trait genetics of blood pressure and QT interval variation
North, TristaBlood stem cell development and regeneration
Novina, CarlMechanisms and Applications of Mammalian RNA interference
Oettinger, MarjorieMolecular Biology of V(D)J Recombination
Olsen, BjornMolecular Biology of Extracellular Matrix
Orkin, StuartHuman Molecular Genetics
Ozcan, UmutMolecular Biology of Insulin and Leptin Receptor Signaling Systems in Obesity
Pandolfi, Pier PaoloThe molecular genetics of human cancer
Park, PeterComputational Genomics
Paw, BarryGenetics of Blood Development
Pellman, DavidNormal cell division mechanisms and cell division defects in cancer
Perelman, LevBioimaging and Optical Spectroscopy: Detection of Early Disease with Light
Perrimon, NorbertGenetic analysis of growth and homeostasis
Pier, GeraldBacterial pathogenesis and vaccine development
Pollak, MartinKidney disease, genetics, cytoskeleton
Polyak, KorneliaMolecular Basis of Breast Cancer Initiation and Progression
Puigserver, PereNutrient Sensing and Metabolic Control
Rabkin, SamuelHSV Vectors for Cancer Therapy
Rajagopal, JayarajLung Regeneration and Lung Disease
Rapoport, TomProtein Transport Across the Endoplasmic Reticulum Membrane
Raychaudhuri, SoumyaDisease-oriented computational genomics and bioinformatics
Reck-Peterson, SamaraMolecular Mechanism of Microtubule-Based Motility
Reich, DavidApplying population genetics to find disease genes
Richardson, CharlesStructure and Replication of DNA
Rinn, JohnThe RNA World
Roberts, CharlesChromatin and Cancer
Roberts, ThomasControl of Gene Expression Tumorgenesis and Differentiation
Rosen, EvanMolecular Approaches to Metabolism and Energy Balance
Rosen, VickiBMP signaling in organogenesis
Rosenberg, PaulGlutamate transporters, cell death, sleep/wake regulation
Rosenzweig, AnthonyMechanisms of heart growth, regeneration, and failure
Rossi, DerrickHematopoietic stem cell biology and aging
Rubin, EricBacterial genetics of tuberculosis and tularemia
Rubin, LeeStem Cells and Neurodegenerative Disease
Rudner, DavidBacterial chromosome dynamics and cell biology
Ruvkun, GaryMolecular Genetics of Development
Sahin, MustafaCellular Mechanism(s) of Axon Guidance
Salic, AdrianMechanisms of vertebrate Hedgehog signaling
Sanes, JoshuaSynapse Formation
Saper, Cliffordhypothalamic circuitry controlling sleep and circadian rhythms
Scadden, DavidHematopoietic stem cells and their niche
Schier, AlexanderDevelopmental Genetics and Neurobiology
Schwarz, ThomasGenetics of Neuronal Cell Biology
Scully, RalphRecombination functions of the BRCA genes
Seed, BrianMolecular Biology of Signal Transduction
Segal, RosalindNeurotrophic factors in development: Functions and mechanisms of action
Seidman, ChristineMolecular genetics basis of human disease, particularly cardiovascular pathogenesis
Seidman, JonathanInherited human disorders
Selkoe, DennisMolecular Mechanisms of Neurodegeneration in Alzheimer's and Parkinsons Diseases
Serhan, CharlesChemical mediators in inflammation and resolution
Shah, JageshSystems Biology Research
Sharpe, ArleneRegulation of T-cell Mediated Immune Response
Sheen, JenMolecular Mechanisms of Plant Signal Transduction
Shi, YangTranscriptional control in differentiation/development & tumorigenesis
Shi, Yujiang GenoEpigenomics and Chromatin Systems Biology
Shih, WilliamBiomolecular nanotechnology
Shivdasani, RameshCancer and development, thrombopoiesis, intestinal development
Shoelson, Steven Signal transduction and related molecular pathophysiology
Sicinski, PeterCell cycle proteins in development and cancer
Silver, PamelaSystems Biology Research
Sinclair, DavidMolecular mechanisms of aging and age related diseases
Slaugenhaupt, SusanGenetics of human disease
Snapper, ScottSignal Transduction, Host-Microbial Interactions and Immunology
Sorger, PeterSystems biology of mammalian signal transduction
Spiegelman, BruceMechanisms of Mammalian Cell Differentiation and Gene Expression
Springer, MichaelEvolution of signaling pathway; quantitative techniques
Springer, TimothyMolecular Basis of cell adhesion and migration
Starnbach, MichaelT-Lymphocyte Responses to Bacterial Pathogens
Stranger, BarbaraPopulation genomics of human transcriptional variation
Struhl, KevinGene regulation in yeast and cancer
Sunyaev, ShamilComputational analysis of sequence variation and divergence
Szostak, JackStructure and Activities of Ribozymes
Tabin, Clifford Vertebrate Pattern Formation
Toker, AlexSignaling Pathways in Cancer Cell Biology
Van Vactor, DavidNeuronal Pathfinding and Synaptogenesis
Vasudevan, ShobhamicroRNA functions in cancers and quiescence
Verdine, GregoryApproaches Toward Understanding and Treating Human Disease
Vidal, MarcFunctional genomics and proteomics
von Andrian, UlrichMolecular Mechanisms of Leukocyte Trafficking
Wagers, AmyBiology and function of tissue-specific stem cells
Wagner, GerhardNMR spectroscopy of proteins and metabolites
Waldor, MatthewBiology and virulence of enteric pathogens
Walensky, LorenTargeting deregulated apoptotic and transcriptional pathways in cancer
Walker, SuzanneChemical biology, enzymology, antibiotics, glycosyltransferases, inhibitors
Walsh, ChristopherMolecular Genetics of Cerebral Cortical Development
Walter, JohannesMaintenance of genome stability in S phase
Walz, ThomasElectron microscopic structure determination
Wang, Da-ZhiCardiovascular development and disease, muscle biology
Warman, MatthewDevelopment and homeostasis of the skeleton
Watnick, PaulaGenetics of bacterial adhesion and pathogenesis
Wei, WenyiCell cycle, Ubiquitination and protein degradation, cancer research
Weinstock, DavidCancer genetics and DNA repair
Weitz, Charles Molecular Biology of Mammalian Circadian Clocks
Wessels, MichaelMolecular pathogenesis of streptococcal infection
Wessling-Resnick, MarianneRegulation of the Cellular uptake of Macromolecular Nutrients
Whelan, SeanTranscriptional Regulation of Viral and Mammalian Genes
Whetstine, JohnathanImpact of Epigenetics on Cellular Homeostasis
White, KristinGenetic control of apoptosis in Drosophila
White, MorrisMolecular and Cellular Mechanisms of Insulin Action
Whitman, MalcolmSignal Transduction During Early Development
Williams, DavidBiology of hematopoietic stem cells
Winston, FredGene Expression in Yeast
Wirth, DyannMolecular Biology of Parasites
Wolfe, MichaelBiochemistry and biology of neurodegenerative diseases
Wong, WesleySingle-molecule Biophysics and Force Spectroscopy
Wu, Ting (C.-ting)Genetics, epigenetics, gene regulation, evolution, disease
Wucherpfennig, KaiMolecular mechanisms of T cell activation
Xavier, RamnikSignaling networks in immunity, Functional analysis of genetic variants associated with autoimmune disease.
Yan, CatherineStem cells, Cancer, and Hematological Disorders
Yang, PriscillaChemistry and biology of Host-virus interactions
Yankner, BruceThe Neurobiology of Alzheimer's disease and related neurodegenerative disorders
Yuan, JunyingMechanisms of Programmed Cell Death
Yusufzai, TimurChromatin and DNA Dynamics
Zetter, BruceMechanisms of Tumor Metastasis
Zhao, JeanKinase signaling in cancer
Zhou, JingCentrosomes, Cilia, Cysts and Diseases
Zhou, QiaoAdult mammalian regeneration
Zon, LeonardDevelopmental Biology of Hematopoiesis
Zou, LeeDNA damage responses and genomic stability