BBS Faculty Member - Meromit Singer

Meromit Singer

Broad Institute of MIT and Harvard
415 Main Street, Room 6035

Cambridge, MA 02142
Email: msinger@broadinstitute.org
Visit my lab page here.



The Singer group focuses on elucidating gene networks that regulate T cell function in cancer and autoimmunity, as well as the mechanisms by which bi-directional interactions take place between the T cells and their environment.

We use statistics, machine learning and algorithmic design to analyze high-throughput data generated in our lab (e.g. single-cell RNA-Seq) and model T cell regulation and function in tissue. We follow up on our predictions with in vivo perturbations (e.g. with CRISPR-Cas9) to validate and improve our models.



Last Update: 1/30/2018



Publications

For a complete listing of publications click here.

 


 



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