BBS Faculty Member - Emanuela Gussoni

Emanuela Gussonie

Department of Genetics

Boston Children's Hospital
Center for Life Sciences Building 15021
3 Blackfan Circle
Boston, MA 02115
Tel: 617-919-2152
Fax: 617-730-0253
Visit my lab page here.

The laboratory focuses on studying tissue-specific stem cells derived from human skeletal muscle. These cells are characterized for biological properties, in vivo interactions with one another, and for mechanisms of specification towards the myogenic lineage. Lastly, muscle stem cells are used in cell-based therapy models. We have interests in designing efficient ways to deliver unaffected cells to mouse models of muscular dystrophy, in particular Duchenne muscular dystrophy.

Another important focus of the laboratory is to identify genes that are regulated during differentiation of human muscle cells, which results in formation of multinucleated myotubes via cell fusion. A better understanding of these processes may reveal important clues on designing successful cell-based therapy of muscle disorders.

Last Update: 5/30/2013


For a complete listing of publications click here.



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