For a complete listing of publications click here.
Weng AP, Ferrando AA, Lee W, Morris IV JP, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC. Activating mutations of NOTCH1 in T cell acute lymphoblastic leukemia. Science 2004; 306:269-71.
Chiang MY, Xu L, Shestova O, Histen G, L'Heureux S, Aster JC*, Pear WS*. Leukemia-associated Notch1 alleles are weak tumor initiators, but impose Notch addiction on K-ras initiated leukemia. J Clin Invest 2008; 118:3181-94.
Ashworth TD, Pear WS, Chiang MY, Blacklow SC, Mastio J, Xu L, Kelliher M, Kastner P, Chan S, Aster JC. Deletion-based mechanisms of Notch1 activation in T-ALL: Key roles for RAG recombinase and a conserved internal translational start site in Notch1. Blood 2010; 116:5455-5464.
Wang H, Zou JY, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC. Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. PNAS, epublished July 7, 2011.