Jon Aster

Brigham and Women's Hospital
75 Francis Street, Thorn 612
Boston, MA 02115
Tel: (617) 525-7329
Fax: (617) 264-5169
Email: jaster@rics.bwh.harvard.edu

References:

• Weng AP, Ferrando AA, Lee W, Morris IV JP, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC. Activating mutations of NOTCH1 in T cell acute lymphoblastic leukemia. Science 2004:306;269-71.
• Weng AP, Millholland JM, Yashiro-Ohtani Y, Laure Arcangeli M, Lau A, Wai C, del Bianco C, Rodriguez C, Sai H, Tobias J, Li Y, Wolfe MS, Shachaf C, Felsher D, Blacklow SC, Pear WS, Aster JC. c-Myc is an important direct target of Notch1 in T cell acute lymphoblastic leukemia/lymphoma. Genes Dev 2006:20;2096-2109.
• Aster JC, Pear WS, Blacklow SC. Notch signaling in leukemia. Annual Review of Pathology: epublished Oct 17