For a complete listing of publications click here.
Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Selkoe DJ. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity. Nature 1999; 398: 513-517.
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smth I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabataini L, Selkoe DJ. Amyloid ß-protein dimers isolated directly from Alzheimer brains impair synaptic plasticity and memory. Nat Med, 2008; 14: 837-842. PMCID: PMC2772133
Bartels T, Choi JG, Selkoe DJ. a-synuclein exists normally in cells and brain as a natively folded tetramer that resists aggregation compared to unfolded monomers. Nature, 2011 Aug 14;477(7362):107-10.
Li S, Jin M, Zhang D, Yang T, Koeglsperger T, Fu H, Selkoe DJ. Environmental novelty potently prevents impairment of hippocampal synaptic plasticity by human Aβ oligomers via a β2-adrenergic signaling pathway. Neuron, 2013; Mar 6;77(5):929-41.
Dettmer U, Newman AJ, Luth ES, Bartels T, Selkoe DJ. In vivo crosslinking reveals principally oligomeric forms of α-synuclein and b-synuclein in neurons and non-neural cells. J Biol Chem, 2013; Mar 1;288(9):6371-85.