For a complete listing of publications click here.
Ryan JA, Brunelle JK, Letai A. 2010. Heightened mitochondrial priming is the basis for apoptotic hypersensitivity of CD4+ CD8+ thymocytes. Proceedings of the National Academy of Science (USA), 107:12895-900. (PMCID: PMC2919900)
Brunelle JK, Ryan JA, Yeceis D, Opferman J, Letai A. 2009. MCL-1 dependent leukemia cells are more sensitive to chemotherapy than BCL-2 dependent counterparts. J Cell Biol 187:429-42.
Letai A. 2008. Diagnosing and exploiting cancer's addiction to blocks in apoptosis. Nature Reviews Cancer, 8: 121-132.
Deng J, Carlson N, Takeyama K, Dal Cin P, Shipp M, Letai A. 2007. BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents. Cancer Cell, 12: 171-185.