For a complete listing of publications click here.
Giorgio Gaglia and Galit Lahav. Constant rate of p53 tetramerization in response to DNA damage controls the p53 response. Molecular Systems Biology, 2014, 10:753:1
Liu JC, Lerou PH and Lahav G (2014) Stem Cells: Balancing resistance and sensitivity to DNA damage. Trends in Cell Biology 24(5):268-274.
Loewer A, Karanam K, Mock C and Lahav G (2013)The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold. BMC Biology; 11:114.
Liu JC, Guan X, Ryan JA, Rivera AG, Mock C, Agrawal V, Letai A, Lerou PH and Lahav G (2013) High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis. Cell Stem Cell 13(4):483-91.
Gaglia G, Guan Y, Shah JV and Lahav G (2013) Activation and control of p53 tetramerization in individual living cells. Proc Natl Acad Sci USA 110(38):15497-501.
Purvis JE and Lahav G (2013) Encoding and decoding cellular information through signaling dynamics. Cell 152(5):945-56.
Karanam K, Kafri R, Loewer A & Lahav G (2012) Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Molecular Cell 47(2):320-9.
Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A and Lahav G (2012) p53 dynamics control cell fate. Science 336(6087):1440-4.
Batchelor E, Loewer A, Mock C and Lahav G (2011) Stimulus-dependent dynamics of p53 in single cells. Mol Syst Biol 7:488.
Loewer A, Batchelor E, Gaglia G and Lahav G (2010) Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. Cell 142 (1):89-100.