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Joanne Yew, Ph.D. Post-doctoral Fellow Email: joanne_yew@hms.harvard.edu Tel: 617-432-1042 |
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I am interested in the role of neuropeptides in modulating aggression in fruit flies. In collaboration with Dr. Yun Wang and Dr. Lingjun Li at the University of Wisconsin-Madison, we are using liquid chromatography coupled to tandem mass spectrometry (MS) to identify and sequence expressed neuropeptides in the adult fly central nervous system. I am also developing MS-based methods to identify neuropeptides that are expressed within populations of aminergic neurons. My other interests include experimental baked goods, experimental cello playing, a sisyphean quest for the perfect brownie recipe, and floating in the ocean, with or without a surfboard. |
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Recent Publications: 1. Yew JY, Davis R, Dikler S, Nanda J, Reinders B, Stretton AO. 2007. Peptide products of the afp-6 gene of the nematode Ascaris suum have different biological actions. J Comp Neurol 502(5):872-82. 2. Yew JY, Kutz KK, Dikler S, Messinger L, Li L, Stretton AO. 2005. Mass spectrometric map of neuropeptide expression in Ascaris suum. J Comp Neurol 488(4):396-413. 3. Yew JY, Dikler S, Stretton AO. 2003. De novo sequencing of novel neuropeptides directly from Ascaris suum tissue using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight. Rapid Commun Mass Spectrom 17(24):2693-8. 4. Hedrick AV, Perez D, Lichti N, Yew J. 2002. Temperature preferences of male field crickets ( Gryllus integer) alter their mating calls. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 188(10):799-805. 5. Gold BG, Yew JY, Zeleny-Pooley M. The immunosuppressant FK506 increases GAP-43 mRNA levels in axotomized sensory neurons. Neurosci Lett 241(1):25-8. |