Cohen Lab Members' Journal Publication List

Ziebell MR, Nirthanan S, Husain SS, Miller KW, and  Cohen JB (2004) "Identification of binding sites in the nicotinic acetylcholine receptor for [3H]azietomidate, a photoactivatable general anesthetic."  Journal of Biological Chemistry  279(17) 17640-17649. abstract

Nirthanan S, Gwee MC (2004) "Three-Finger alpha-Neurotoxins and the Nicotinic Acetylcholine Receptor, Forty Years On." J Pharmacol Sci. 94(1):1-17.  abstract

Chiara DC
, Dangott LJ, Eckenhoff RG, and  Cohen JB (2003) "Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane." Biochemistry 42(46) 13457-13467. abstract

Nirthanan S, Charpantier E, Gopalakrishnakone P, Gwee MC, Khoo HE, Cheah LS, Kini MR, and Bertrand D (2003) "Neuromuscular effects of candoxin, a novel toxin from the venum of the Malayan krait (Bungarus candidus)" Br J Pharmacol 139(4) 832-844. abstract

Nirthanan S, Gopalakrishnakone P, Gwee MC, Khoo HE, and Kini MR (2003) "Non-conventional toxins from Elapid venom" Toxincon 41(4) 397-407. abstract

Paaventhan P, Joseph JS, Nirthanan S, Rajaseger G, Gopalakrishnakone P, Kini MR, and Kolatkar (2003) "Crystallization and preliminary X-ray analysis of candoxin, a novel reversible neurotoxin from the Malayan krait Bungarus candidus" Acta Crystallogr D Biol Crystallogr 59 584-586. abstract

Chiara DC
, Trinidad JC, Wang D, Ziebell MR, Sullivan D, and  Cohen JB (2003) "Identification of amino acids in the nicotinic acetylcholine receptor agonist binding site and ion channel photolabeled by 4-[(3-trifluoromethyl)-3H-diazirin-3-yl]benzoylcholine, a novel photoaffinity antagonist" Biochemistry 42(2) 271-283. abstract

Sawyer GW, Chiara DC, Olsen RW, and  Cohen JB (2002) "Identification of the Bovine Gamma-Aminobutyric Acid Type A Receptor Alpha Subunit Residues Photolabeled by the Imidazobenzodiazepine [3H]Ro15-4513" Journal of Biological Chemistry 277(51) 50036-50045. abstract

Watanabe L, Nirthanan S, Rajaseger G, Polikarpov I, Kini RM, Arni RK (2002) "Crystallization and preliminary X-ray analysis of bucain, a novel toxin from the Malayan krait Bungarus candidus" Acta Crystallogr D Biol Crystallogr 58 1879-81. abstract

Gwee MC, Nirthanan S, Khoo HE, Gopalakrishnakone P, Kini RM, and Cheah LS (2002) "Autonomic effects of some scorpion venoms and toxins" Clinical Experimental Pharmacology Physiology 29(9) 795-801. abstract

Nirthanan S
, Gao R, Gopalakrishnakone P, Gwee MC, Khoo HE, Cheah LS, and Manjunatha Kini R (2002) "Pharmacological characterization of mikatoxin, an alpha-neurotoxin isolated from the venom of the New-Guinean small-eyed snake Micropechis ikaheka" Toxicon 40(7) 863-871.  abstract

Nirthanan S
, Charpantier E, Gopalakrishnakone P, Gwee MC, Khoo HE, Cheah LS, Bertrand D, and Kini RM (2002) "Candoxin, a novel toxin from Bungarus candidus, is a reversible antagonist of muscle (alphabetagammadelta ) but a poorly reversible antagonist of neuronal alpha 7 nicotinic acetylcholine receptors" Journal of Biological Chemistry 277(20) 17811-17820.  abstract

Cheah LS, Gwee MC, and Nirthanan S (2002) "Characterization of the rat isolated retractor penis muscle as a model for the study of nitrergic transmission" Journal of Pharmacology and Toxicology Methods 47(2) 79-85. abstract

Sullivan D
, Chiara DC, and Cohen JB (2002) "Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: antagonist footprint and secondary structure prediction." Molecular Pharmacology 61(2) 463-472. abstract

Nirthanan S
, Joseph JS, Gopalakrishnakone P, Khoo HE, Cheah LS, and Gwee MC (2002) "Biochemical and pharmacological characterization of the venom of the black scorpion Heterometrus spinifer" Biochemical Pharmacology 63(1) 49-55. abstract

Torres AM, Kini RM, Selvanayagam N, Kuchel PW (2001) "NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait (Bungarus candidus)" Biochemical Journal 360 539-48. abstract

Gallagher MJ, Chiara DC, and Cohen JB (2001) "Interactions Between 3-(trifluoromethyl)-3-(m-[ 125I]iodophenyl)diazirine and Tetracaine, Phencyclidine, or Histrionicotoxin in the Torpedo Nicotinic Acetylcholine Receptor Ion Channel" Molecular Pharmacology 59(6) 1514-1522. abstract

Ramarao MK, Bianchetta MJ, Lanken J, and Cohen JB (2001) "Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering" Journal of Biological Chemistry 276(10) 7475-7483. abstract

Srinivasan KN, Nirthanan S, Sasaki T, Sato K, Cheng B, Gwee MC, Kini RM, and Gopalakrishnakone P (2001) "Functional site of bukatoxin, an alpha-type sodium channel neurotoxin from the Chinese scorpion (Buthus martensi Karsch) venom: probable role of the (52)PDKVP(56) loop" FEBS Letters 494(3) 145-149. abstract

Chiara DC
, Kloczewiak MA, Addona GH, Yu J-A, Cohen JB, and Miller KW (2001) "Site of Resting State Inhibition of the Nicotinic Acetylcholine Receptor by a Hydrophobic Inhibitor" Biochemistry 40(1) 296-304.

Wang, D, Chiara, DC, Xie, Y, and Cohen JB (2000) "Probing the Structure of the Nicotinic Acetylcholine Receptor with 4-Benzoylbenzoylcholine, a Novel Photoaffinity Competitive Antagonist" Journal of Biological Chemistry 275(37) 28666-28674. abstract

Sullivan, DA
and Cohen JB (2000) "Mapping the agonist binding site of the nicotinic acetylcholine receptor: Orientation requirements for activation by covalent agonist." Journal of Biological Chemistry 275(17):12651-60 abstract

Chiara DC, Xie Y, and Cohen JB (1999) "Structure of the agonist binding sites of the Torpedo nicotinic acetylcholine receptor: affinity labeling and mutational analyses identify gTyr-111/ dArg-113 as antagonist affinity determinants " Biochemistry 38 6689-6698. abstract

Chiara DC, Middleton RE, and Cohen JB (1998) "Identification of tryptophan 55 as the primary site of [3H]nicotine photoincorporation in the g -subunit of the Torpedo nicotinic acetylcholine receptor." FEBS Letters 423(2):223-6. abstract

Chiara DC
and Cohen JB (1997) "Identification of amino acids contributing to high and low affinity d-tubocurarine sites in the Torpedo nicotinic acetylcholine receptor." Journal of Biological Chemistry 272(52) :32940-50. abstract

Sullivan DA
, Holmqvist MH, and Levitan IB (1997) "Characterization of gating and peptide block of mSlo, a cloned calcium-dependent potassium channel." Journal of Neurophysiology 78(6):2937-50. abstract

Salih E, Chishti SB, Vicedomine P, Cohen SG, Chiara DC, and Cohen JB (1994) "Active-site peptides of acetylcholinesterase of Electrophorus electricus : labelling of His-440 by 1-bromo-[2-14C]pinacolone and Ser-200 by tritiated diisopropyl fluorophosphate." Biochimica et Biophysica Acta 1208(2) :324-31. abstract

Sacchettini, JC, Frazier, MW, Chiara DC , Banaszak, LJ, and Grant, GA (1988) "Amino Acid Sequence of Porcine Heart Fumarase." Biochemical and Biophysical Research Communications 153 , 435-440. abstract



Last updated on August 30, 2004

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