CURRENT POSITION

• Research Associate
• Harvard Medical School (2000-) Boston, Massachusetts
• Department of Neurobiology


EDUCATION
 

• Postdoc Fellowship
• Harvard Medical School (1997-2000) Boston, Massachusetts
• Principal Investigator: Jonathan B. Cohen, Ph.D., Professor of Neurobiology
• Ph.D.
• Washington University School of Medicine, St. Louis, Missouri
• Biomedical Sciences: Neuroscience (MSTP)
• Defended January, 1996, Awarded concurrent with M.D. May 1997
• Thesis Title: "Structural Studies of the Nicotinic Acetylcholine Receptor, a Ligand-Gated Ion Channel"
• Principal Investigator: Jonathan B. Cohen, Ph.D.
• M.D.
• Washington University School of Medicine, St. Louis, Missouri 1997
• B.S.
• University of California, Davis, California 1984
• Major: Mathematics, Minor: Biology
• A.A.
• Shasta College, Redding, California 1986
• General Education


PUBLICATIONS

MEETING ABSTRACTS

• Sawyer, G.W., Chiara, D.C., Cohen, J.B. and Olsen, R.W. "Characterization of the Site of Photoincorporation of [³H]Ro15-4513 into Affinity-Purified GABA_A Receptor a-Subunit"  Society for Neuroscience Abstracts, 2001 (pending)
• Chiara, D.C., Eckenhoff, R.G., Dangott, L.J., and Cohen, J.B. "A Binding Site for the Volatile Anesthetic Halothane within the Nicotinic Acetylcholine Receptor Identified By Photoaffinity Labeling" Biophysical Journal Abstracts, 2000, 78, 360A  Abstract.
• K.W. Miller, S.A. Forman, M.A. Kloczewaik, G.H. Addona, S.S. Husain, D.C. Chiara, M.B. Pratt, and J.B. Cohen. "Sites of Anesthetic Action on the Nicotinic Acetylcholine Receptor" Progress in Anesthetic Mechanism, 2000, 8.  Abstract.
• Chiara, D.C, Wang, D., Xie, Y., Trinidad, J.C., and Cohen, J.B. "Novel Photoreactive Choline Esters as Probes of the Structure of the Nicotinic Acetylcholine Receptor Agonist Binding Site" Protein Science, 1999, 8, p70, 82-M, Abstract.
• Miller, K.W., Addona, G.H., Chiara, D.C., Husain, S.S., Pratt, M.B., and Cohen, J.B. "Interactions of Anesthetics with the Nicotinic Acetylcholine Receptor and Other Proteins," Archives of Pharmacology, 1999, 359, R3.
• Chiara, D.C., Addona, G.H., Kloczewiak, M.A., Cohen, J.B., and Miller, K.W. "Time-Resolved Photolabeling of the Nicotinic Acetylcholine Receptor Identifies the Site of Action of a Resting State Inhibitor," Biophysical Journal Abstracts, 1999, 76, A372 Abstract.
• Chiara, D.C. and Cohen, J.B., "Desensitization of the Torpedo Nicotinic Acetylcholine Receptor (nAChR) Linked to Movement of the Agonist Site Residues Trp-55 and Trp-57," Biophysical Journal Abstracts, 1995, 68, A406 Abstract.
• Xie, Y., Chiara, D.C., and Cohen, J.B., "Mutational Analysis of Novel Residues Identified Within the Binding Site of d-Tubocurarine of Torpedo Acetylcholine Receptor," Society for Neuroscience Abstracts, 1994, 20, 466.5.
• Cohen, J.B., Blanton, M.B., Chiara, D.C., Sharp, S.D., and White, B.H. "Structural Organization of Functional Domains of the Nicotinic Acetylcholine Receptor," J. Cell Biochem., Keystone Symposia on Molecular and Cellular Biology, 1992, 16E, 217-T003.
• Chiara, D.C. and Cohen, J.B., " Identification of Amino Acids Contributing to High and Low Affinity d-Tubocurarine (dTC) Sites on the Torpedo Nicotinic Acetylcholine Receptor," Biophysical Journal Abstracts, 1992, 61, A106 & FASEB Journal Abstracts, 1992, 6, A106.
• Chiara, D.C., Sacchettini, J.C., Frazier, M.W., Banaszak, L,J., and Grant, G.A., "Structure of Porcine Heart Fumarase," The Protein Society Symposium, Program and Abstracts, 1988, 2, S104.