PROGRAM 

 

Complete program of the Meeting can be downloaded in .pdf format here.

 

 

Thursday 5th July 2007

 

 

15:00 – 18:00          REGISTRATION/RECEPTION

 

  

Friday 6th July 2007

 

 

09:00 – 10:20           OPENNING SESSION        

 

 

Time                      Speaker                                          Title of Presentation

 

09:00 – 09:10          WELCOME – Amin I. Kassis

                             

09:10 – 10:00          CONFERENCE LECTURE                Auger Processes in the 21st Century

                              Speaker:        Roger W. Howell

                              Introducer:     S. James Adelstein

 

10:00 – 10:20          COFFEE

 

 

10:20 – 12:20          SESSION I – MOLECULAR EFFECTS        

                              Chair:  Roger F. Martin

 

Time                      Speaker                                       Title of Presentation

10:20 – 11:00          Thomas Winters       

                              (Invited Lecture)

                              Introducer:   Roger F. Martin

 Understanding 125I decay-induced DNA DSB molecular structure: Possible roles of such structures in cytotoxicity 
 

11:00 – 11:20          Balagurumoorthy, P
DNA DSB Induced by decay of 123I-labeled Hoechst 33342: Role of DNA topology.
 


 
11:20 – 11:40          Lobachevsky, PN
DNA Breakage from decay of iodine-124.
 
11:40 – 12:00          Martin, RF
Plasmid breakage by 125I-labelled DNA ligands: Effect of DNA–iodine atom distance on breakage efficiency.
 
12:00 – 12:20          Gaynutdinov, TI

Iodine-125 radioprobing of intramolecular quadruplex conformation of human telomeric DNA: Effects of flanking sequences, ionic conditions, and quadruplex-specific drugs.
 

 

12:20 – 13:30          LUNCH

 

 

13:30 – 14:30          POSTER VIEWING
 

 

Friday 6th July 2007

 

14:30 – 16:30          SESSION II – FUNDAMENTAL PROPERTIES, PHYSICS & DOSIMETRY

                              Chair:  Ekkehard Pomplun

 

 

Time                      Speaker                                    Title of Presentation

 
The Auger effect and radiationless transitions in physical and biological research.
                             

14:30 – 15:15          Hooshang Nikjoo

                              (Invited Lecture)

                              Introducer: Michel Terrissol

15:15 – 15:35          Terrissol, M


DNA Damage in plasmid pBR322 after
iodine-123 and iodine-125 decay.
 
 
15:35 – 15:55          Girard, PM


Simulation of radioprobing experiments to study DNA quadruplex structure and topology.
 
 

15:55 – 16:30          COFFEE

 

16:30 – 17:55          SESSION III – SYNCHROTRON RADIATION INDUCED AUGER PROCESSES

                              Chair: Michel Terrissol

 

 

Time                      Speaker                                    Title of Presentation

16:30 – 17:15          Akinari Yokoya

                              (Invited Lecture)

                              Introducer: Hooshang Nikjoo

 Studies of soft-x-ray-induced Auger effect on the induction of DNA damage.
 
17:15 – 17:35          Fujii, K

 
 

Induction of strand breaks, base lesions, and clustered damage in dry plasmid DNA films induced by carbon, nitrogen, and oxygen KLL Auger process.
 
17:35 – 17:55          Akamatsu, K

Auger and photo-electron effects on strand breaks and base lesions in plasmid DNA irradiated with ultrasoft x-rays.

  
 


 

 

19:00 – 22:00          CONFERENCE DINNER

                              Veronique Restaurant

                              20 Chapel Street

                              Brookline

 

  

 

Saturday 7th  July 2007

 

 

9:00 – 12:30            SESSION IV – CELLULAR EFFECTS

                              Chair: Linda Yasui

 

 

Time                      Speaker                                    Title of Presentation

09:00 – 09:20          Schomaecker, K Radiation Damage to keratinocytes, tumour cells and human embryo stem cells by 125I-labelled deoxyuridine (dU).
 
09:20 – 09:40          Neti, PVSV Intercellular Communication in Testicular Responses to DNA-incorporated 125I.
 
09:40 – 10:00          Fischer, T Diethylstilbestrol (DES) labeled with Auger emitters: Potential radiopharmaceutical for therapy of estrogen receptor-positive tumours and their metastases?
 

10:00 – 10:30          COFFEE

10:30 – 10:50          Costantini, DL 111In-Labeled trastuzumab (Herceptin) modified with nuclear localization sequences: Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer.
 
10:50 – 11:10          Cai, Z DNA damage produced by 111In-DTPA-hEGF correlates with EGFR expression level and radiosensitivity in breast cancer cell lines.
 
11:10 – 11:30          Yasui, LS

Gadolinium neutron capture in glioblastoma multiforme cells.
 
 

11:30 – 12:30          POSTER VIEWING

 

 

12:30 – 14:00          LUNCH

 

 

 

 

14:00 – 16:15          SESSION V – CANCER THERAPY 

                              Chair:  R. Howell

 

 

Time                      Speaker                                    Title of Presentation

14:00 – 14:20          Rousseau, J

Iodine-enhanced synchrotron stereotactic radiotherapy.
 
 
14:20 – 14:40          Mattes, MJ

 
Therapy of carcinoma xenografts with 111In-conjugated Abs to EGFr and HER-2.
 
14:40 – 15:00          Pouget, JP

 
Biological Efficiency of 125I in radioimmuno-therapy of small solid tumors: In vitro and in vivo Studies.
 
15:00 – 15:20          Kassis, AI

 
First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus 125IUdR.
 
15:20 – 15:40           SUMMARY                   S. James Adelstein

 
 
 


  

15:40                      CLOSE OF MEETING    Amin I. Kassis